HIDEYUKI Ohtake 大竹秀幸

Researcher Number	60336237
External Links
Affiliation (based on the past Project Information) *help	2007 – 2009: Kumamoto University, 医学部附属病院, 助教 2008: Kumamoto University, 医学部・附属病院, 助教 2006: 熊本大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 腫瘍免疫 / colosoric acid / STAT3 / 腹腔マクロファージ / 腹膜播種 / 卵巣癌 / 婦人科腫瘍学 / 卵巣表層上皮細胞 / hCG受容体 / LH … More / βサブニット / 絨毛ゴナドトロピン / 上皮性卵巣癌 / 癌 / 遺伝子 / 細胞・組織 / 組織 / 細胞 … More Except Principal Investigator 上皮性卵巣癌 / 卵巣表層上皮 / 癌 / 遺伝子 / 細胞・組織 / 卵巣癌モデル / 卵巣癌治療 / 癌幹細胞 / 卵巣表層上皮細胞 / βサブニット / hCG受容体 / LH / βサブユニット / 絨毛ゴナドトロピン / 婦人科腫瘍学 / K-ras / Wint / PI3K / 上皮生卵巣癌 / hTERT導入 / HPV E7 / 不死化ヒト卵巣表層上皮細胞株 / k-ras / β-catenin / Wnt / Pten / PI3 / 明細胞腺癌 / 類内膜腺癌 / 不死化 Less

The development of novel therapeutic strategies for targeting ovarian cancer stem cells
- Principal Investigator
  
  KATABUCHI Hidetaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kumamoto University
Novel strategy to control the differentiation of macrophages in ascites for the suppression of ovarian cancer disseminationPrincipal Investigator
- Principal Investigator
  
  TASHIRO Hironori, 大竹秀幸
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kumamoto University
Investigation for ovarian cancer therapy focusing on production of human chorionic gonadotropin beta subunit
- Principal Investigator
  
  TASHIRO Hironori
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kumamoto University
An ovarian carcinoma model using immortalized human ovarian surface epithelial cells without chromosomal instability
- Principal Investigator
  
  KATABUCHI Hidetaka
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kumamoto University
Cell transformation of the immortalized ovarian surface epithelial cells co-cultured with endometrial stromal cellsPrincipal Investigator
- Principal Investigator
  
  OHTAKE Hideyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kumamoto University

All 2011 2010 2009 2008 2006

All Journal Article Presentation

[Journal Article] Mutual contribution of Pten and estrogen to endometrial carcinogenesis in a PtenloxP/loxP mouse model2011
- Author(s)
  F. Saito, H. Tashiro, Y. To, H. Ohtake, T. Ohba, A. Suzuki, H. Katabuchi
- Journal Title
  
  Int J Gynecol Cancer
  
  Volume: 21 Pages: 1343-1349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390454
[Journal Article] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies : a novel insight to the molecular pathogenesis of ovarian epithelial carcinoma.2010
- Author(s)
  Motohara T., Tashiro H., Miyahara Y., Sakaguchi I., Ohtake H., Katabuchi H.
- Journal Title
  
  Cancer Science 101
  
  Pages: 1550-1556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591938
[Journal Article] Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation2010
- Author(s)
  Kiyomi Takaishi, Yoshihiro Komohara, Hironori Tashiro, Hideyuki Ohtake, Takenobu Nakagawa, Hidetaka Katabuchi, and Motohiro Takeya
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2128-2136
- NAID
  10027832147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592137
[Journal Article] Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation2010
- Author(s)
  K. Takaishi, Y. Komohara, H. Tashiro, H. Ohtake, T. Nakagawa, H. Katabuchi, M. Takeya
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2128-2136
- NAID
  10027832147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390454
[Journal Article] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies : A novel insight into the molecular pathogenesis of ovarian epithelial carcinoma2010
- Author(s)
  T. Motohara, H. Tashiro, Y. Miyahara, I. Sakaguchi, H. Ohtake, H. Katabuchi
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1550-1556
- NAID
  10026594146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390454
[Journal Article] Structural changes and cell properties of human ovarian surface epithelium in ovarian pathophysiology2006
- Author(s)
  Okamura H, Katabuchi H, Nitta M, Ohtake H
- Journal Title
  
  Microsc Res Tech 69
  
  Pages: 469-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390450
[Journal Article] 当科で経験した外科的切除を行った腸管あるいは尿路子宮内膜症12例の臨床病理学的検討2006
- Author(s)
  角田みか, 斎藤文誉, 岡村佳則, 大竹秀幸
- Journal Title
  
  エンドメトリオーシス研究会誌 27
  
  Pages: 137-141
- Data Source
  KAKENHI-PROJECT-18591838
[Journal Article] Structural changes and properties of human ovarian surface epithelium in ovarian pathophysiology2006
- Author(s)
  H.Okamura, H.Katabuchi, M.Nitta, H.Ohtake
- Journal Title
  
  Microscopy Research and Technique 69
  
  Pages: 469-481
- Data Source
  KAKENHI-PROJECT-18390450
[Journal Article] Structural changes and properties of human ovarian surface epithelium in ovarian pathophysiology2006
- Author(s)
  H.Okamura, H.Katabuchi, M.Nitta, H.Ohtake
- Journal Title
  
  Microscopy Research and Technique 69
  
  Pages: 469-481
- Data Source
  KAKENHI-PROJECT-18591838
[Presentation] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies2011
- Author(s)
  T. Motohara, H. Tashiro, H. Ohtake, R. Honda, T. Ohba, H. Katabuchi
- Organizer
  The 50th annual congress of Taiwan Association of Obstetrics and Gynecology
- Place of Presentation
  Kaohsiung
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-21390454
[Presentation] 進行卵巣癌腹水中のM2マクロファージは転写因子STAT3を介して卵巣癌細胞を増殖させる2010
- Author(s)
  高石清美, 田代浩徳, 大竹秀幸, 片渕秀隆
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] The 2010 Annual Meeting of Taiwan Association of Obstetrics and Gynecology-the International Young Doctors Session2010
- Author(s)
  Kiyomi Takaishi, Hironori Tashiro, Hideyuki Ohtake, Takashi Ohba, and Hidetaka Katabuchi
- Organizer
  The effect of macrophage on cancer cell in ascitic fluid of advanced epithelial ovarian cancers
- Place of Presentation
  台中台湾Windsor Hotel
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] 進行卵巣癌腹水中のM2マクロファージは転写因子STAT3を介して卵巣癌細胞を増殖させる2010
- Author(s)
  高石清美, 田代浩徳, 大竹秀幸, 他
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム,東京
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] 進行卵巣癌の腹腔マクロファージと癌細胞の細胞相互作用2009
- Author(s)
  高石清美, 田代浩徳, 大竹秀幸, 大場隆, 片渕秀隆
- Organizer
  第24回日本生殖免疫学会総会・学術集会
- Place of Presentation
  東京京王プラザホテル
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] 卵巣癌進行期の腹腔内微小環境におけるM2マクロファージの関与2009
- Author(s)
  高石清美, 田代浩徳, 大竹秀幸, 他
- Organizer
  第8回日本婦人科がん分子標的研究会学術集会
- Place of Presentation
  福岡市博多エクセルホテル東急
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] 進行卵巣癌の腹腔マクロファージと癌細胞の細胞相互作用2009
- Author(s)
  高石清美, 田代浩徳大竹秀幸, 他
- Organizer
  第24回日本生殖免疫学会学術集会
- Place of Presentation
  東京都京王プラザホテル
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21592137
[Presentation] ヒト正常卵巣表層上皮細胞を用いた上皮性卵巣癌の発癌機構の解析2008
- Author(s)
  佐々木瑠美、田代浩徳、大竹秀幸、片渕秀隆
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-18591838

1. HIRONORI Tashiro (70304996)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
2. KATABUCHI Hidetaka (90224451)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
3. MOTOHARA Takeshi (10457591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. TAKAISHI Kiyomi (00601303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

HIDEYUKI Ohtake 大竹 秀幸

Research Projects

Research Products

Co-Researchers

The development of novel therapeutic strategies for targeting ovarian cancer stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel strategy to control the differentiation of macrophages in ascites for the suppression of ovarian cancer disseminationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for ovarian cancer therapy focusing on production of human chorionic gonadotropin beta subunit

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An ovarian carcinoma model using immortalized human ovarian surface epithelial cells without chromosomal instability

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell transformation of the immortalized ovarian surface epithelial cells co-cultured with endometrial stromal cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mutual contribution of Pten and estrogen to endometrial carcinogenesis in a PtenloxP/loxP mouse model2011

Author(s)

Journal Title

Data Source

[Journal Article] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies : a novel insight to the molecular pathogenesis of ovarian epithelial carcinoma.2010

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies : A novel insight into the molecular pathogenesis of ovarian epithelial carcinoma2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Structural changes and cell properties of human ovarian surface epithelium in ovarian pathophysiology2006

Author(s)

Journal Title

Data Source

[Journal Article] 当科で経験した外科的切除を行った腸管あるいは尿路子宮内膜症12例の臨床病理学的検討2006

Author(s)

Journal Title

Data Source

[Journal Article] Structural changes and properties of human ovarian surface epithelium in ovarian pathophysiology2006

Author(s)

Journal Title

Data Source

[Journal Article] Structural changes and properties of human ovarian surface epithelium in ovarian pathophysiology2006

Author(s)

Journal Title

Data Source

[Presentation] Long-term oncological outcomes of ovarian serous carcinomas with psammoma bodies2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 進行卵巣癌腹水中のM2マクロファージは転写因子STAT3を介して卵巣癌細胞を増殖させる2010

HIDEYUKI Ohtake 大竹秀幸