Ikoma Yoko 生駒洋子

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IKOMA Yoko 生駒洋子

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Researcher Number	60339687
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所分子イメージング診断治療研究部, 主幹研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所分子イメージング診断治療研究部, 主幹研究員 2022: 国立研究開発法人量子科学技術研究開発機構, 量子生命・医学部門量子医科学研究所分子イメージング診断治療研究部, 主幹研究員 2021: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所分子イメージング診断治療研究部, 主幹研究員 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所分子イメージング診断治療研究部, 主幹研究員(定常) 2017 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所分子イメージング診断治療研究部, 主任研究員(定常) … More 2015: 国立研究開発法人放射線医学総合研究所, 分子イメージング研究センター, 主任研究員 2012 – 2014: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 主任研究員 2009: 奈良先端科技大, 情報科学研究科, 助教 2008: Nara Institute of Science and Technology, 情報科学研究科, 特任助教 2006 – 2007: 独立行政法人放射線医学総合研究所, 分子イメージング研究センター, 研究員 2005: 独立行政法人放射線医学総合研究所, 重粒子医科学センター脳機能イメージング研究開発推進室, 研究員 2004: 独立行政法人放射線医学総合研究所, 脳機能イメージング研究開発推進室, 研究員 Less
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52040:Radiological sciences-related / Medical Physics and Radiological Technology Except Principal Investigator Radiation science
Keywords	Principal Investigator 血行動態 / ダイナミック造影MRI / 薬物動態解析 / PET / 機械学習 / 結合能 / 乳腺腫瘍 / 深層学習 / 生体生命情報学 / 特徴量抽出 … More / 前立腺腫瘍 / クラスタリング / 放射線 / 脳神経疾患 / セロトニン / 受容体結合能 / [^<11>C]racloride / 複数回投与法 / [^<11>C]raclopride / 受容体 / ドーパミン / 分布容積 / [^<11>C]DAA1106 / 末梢性ベンゾジアゼピン受容体 / 活性型ミクログリア … More Except Principal Investigator PET / Dopamine / Radiology / Brain / ドーパミン / 放射線 / 脳・神経 Less

Quantitative evaluation of blood circulation using a machine learning generated blood input function in dynamic contrast-enhanced breast MRIPrincipal Investigator
- Principal Investigator
  
  生駒洋子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Quantitative evaluation of blood circulation by deep learning in short time DCE-MRIPrincipal Investigator
- Principal Investigator
  
  生駒洋子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Mapping of tumor circulatory function using time course pattern in DCE-MRIPrincipal Investigator
- Principal Investigator
  
  IKOMA Yoko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical Physics and Radiological Technology
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
PET measurement of serotonin release in brain for investigation into effect of SSRI in depressionPrincipal Investigator
- Principal Investigator
  
  IKOMA Yoko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  National Institute of Radiological Sciences
Development of shortened PET measurement method for investigation of the dopamine function in psychiatric disordersPrincipal Investigator
- Principal Investigator
  
  IKOMA Yoko
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Institute of Science and Technology
Construction of Normal Database of Neurotransmission System in the Human Brain using Positron emission tomography
- Principal Investigator
  
  ITO Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
PETによる[^<11>C]DAA1106を用いた脳内活性型ミクログリアの非侵襲的定量Principal Investigator
- Principal Investigator
  
  生駒洋子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  National Institute of Radiological Sciences

All 2023 2022 2020 2018 2017 2016 2015 2014 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-2007
- Author(s)
  生駒洋子
- Publisher
  エヌ・ティー・エス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Reference region extraction by clustering for the pharmacokinetic analysis of dynamic contrast-enhanced MRI in prostate cancer2020
- Author(s)
  Yoko Ikoma, Riwa Kishimoto, Yasuhiko Tachibana, Tokuhiko Omatsu, Goro Kasuya, Hirokazu Makishima, Tatsuya Higashi, Takayuki Obata, Hiroshi Tsuji
- Journal Title
  
  Magnetic Resonance Imaging
  
  Volume: 66 Pages: 185-192
- DOI
  10.1016/j.mri.2019.08.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09077
[Journal Article] Quantitative analysis for estimating billding potential of the peripheral benzodiazepine receptor with[11C]DAA11062007
- Author(s)
  Ikoma Y
- Journal Title
  
  J Cereb Blood Flow Metab 27
  
  Pages: 173-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [^<11>C]DAA11062007
- Author(s)
  Ikoma Y
- Journal Title
  
  J Cereb Blood Flow Metab 27
  
  Pages: 173-184
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [11C] DAA11062007
- Author(s)
  Ikoma Y
- Journal Title
  
  J Cereb Blood Flow Metab 27
  
  Pages: 173-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis of 11C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function2006
- Author(s)
  Ikoma Y
- Journal Title
  
  J Nucl Med 47
  
  Pages: 1531-1537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analyses of ^<18>F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain2006
- Author(s)
  Fujimura Y, Ikoma Y, Yasuno F, Suhara T, Ota M, Matsumoto R, Nozaki S, Takano A, Kosaka J, Zhang MR, Nakano R, Suzuki K, Kato N, Ito H
- Journal Title
  
  J Nucl Med 47
  
  Pages: 43-50
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis of ^<11>C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function2006
- Author(s)
  Ikoma Y
- Journal Title
  
  J Nucl Med 47
  
  Pages: 1531-1537
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis of dopamine synthesis in human brain using positron emission tomography with L-〔β-^11C〕DOPA2006
- Author(s)
  Ito H, Ota M, Ikoma Y, Seki C, Yasuno F, Takano A, Maeda J, Nakano R, Suzuki K, Suhara T
- Journal Title
  
  Nucl Med Commun 27
  
  Pages: 723-731
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Effects of image reconstruction algorithm on neurotransmission PET studies in humans : comparison between filtered backprojection and orderdsubsets expectation maximization2006
- Author(s)
  Morimoto T, Ito H, Takano A, Ikoma Y, Seki C, Okauchi T, Tanimoto K, Ando A, Shiraishi T, Yamaya T, Suhara T
- Journal Title
  
  Ann Nucl Med 20
  
  Pages: 237-243
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Evaluation of in vivo P-glycoprotein function at the blood-brain barrier Among MDR1 gene polymorphisms by using ^<11>C-verapamil2006
- Author(s)
  Takano A, Kusuhara H, Suhara T, Ieiri I, Morimoto T, Lee YJ, Maeda J, Ikoma Y, Ito H, Suzuki K, Sugiyama Y
- Journal Title
  
  J Nucl Med 47
  
  Pages: 1427-1433
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative analysis of ^<11>C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function2006
- Author(s)
  Ikoma Y, Takano A, Ito H, Kusuhara H, Sugiyama Y, Arakawa R, Fukumura T, Nakao R, Suzuki K, Suhara T
- Journal Title
  
  J Nucl Med 47
  
  Pages: 1531-1537
- Data Source
  KAKENHI-PROJECT-18591372
[Journal Article] Quantitative Analysis for Estimation Binding Potential of the Peripheral Benzodiazepine Receptor with [^<11>C]DAA1106
- Author(s)
  Yoko Ikoma
- Journal Title
  
  Journal of Cerebral Blood Flow and Metabolism (in press)
- Data Source
  KAKENHI-PROJECT-16790709
[Presentation] ダイナミック造影MRIにおけるwashout速度の簡易定量法と汎用ソフトウェアの開発2023
- Author(s)
  生駒洋子、岸本理和、尾松徳彦、立花泰彦、小畠隆行
- Organizer
  第51回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-20K08041
[Presentation] 乳腺ダイナミック造影MRIにおける血行動態の簡易指標マッピングと汎用ソフトウェア開発2022
- Author(s)
  生駒洋子、尾松徳彦、岸本理和、立花泰彦、小畠隆行
- Organizer
  第50回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-20K08041
[Presentation] ダイナミック造影MRIにおける血行動態マッピングのための汎用ソフトウェア開発2020
- Author(s)
  生駒洋子，立花泰彦，岸本理和，尾松徳彦，東達也，辻比呂志，小畠隆行
- Organizer
  第48回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-17K09077
[Presentation] ダイナミック造影MRIによる循環動態定量化における参照領域の自動抽出法の検討2018
- Author(s)
  生駒洋子、小畠隆行、立花泰彦、尾松徳彦、岸本理和、東達也、辻比呂志
- Organizer
  第57回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-17K09077
[Presentation] ダイナミック造影MRIにおける濃度変化パターンに基づいた参照領域抽出法の検討2017
- Author(s)
  生駒洋子、小畠隆行、立花泰彦、尾松徳彦、岸本理和、東達也、辻比呂志
- Organizer
  第36回日本医用画像工学会大会
- Data Source
  KAKENHI-PROJECT-17K09077
[Presentation] PET動態解析によるシナプス間隙におけるセロトニン濃度変化の定量評価2016
- Author(s)
  生駒洋子, 田桑弘之, 西野明日香, 関千江, 前田純
- Organizer
  JAMITフロンティア2016
- Place of Presentation
  ぶんかテンブス館（沖縄県・那覇市）
- Year and Date
  2016-01-19
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] [18F]altanserin-PETを用いた覚醒下マウスにおける内因性セロトニン変化の測定2015
- Author(s)
  生駒洋子, 田桑弘之, 西野明日香, 前田純
- Organizer
  第55回日本核医学会学術総会
- Place of Presentation
  ハイアットリージェンシー東京（東京都・新宿区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] 小動物PETにおける[11C]racloprideを用いたドーパミン放出測定の精度評価2014
- Author(s)
  生駒洋子、田桑弘之、関千江、徳永正希、木村泰之、伊藤浩
- Organizer
  第54回日本核医学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] Measurement of dopamine release by a single PET scan with multiple injections of [11C]raclopride: Evaluation of reproducibility in binding potential under rest conditions2014
- Author(s)
  Ikoma Y, Kimura Y, Takano H, Kodaka F, Yamada M, Suhara T, Ito H
- Organizer
  Neuroreceptor Mapping 2014
- Place of Presentation
  オランダ、アムステルダム
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] [^<11>C]raclopride複数回投与によるPETを用いた受容体結合能変化の短時間測定2008
- Author(s)
  生駒洋子
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉市
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20790839
[Presentation] Quantitative assessment of changes in binding potential with reference tissue model and multiple injection of [^<11>C]raclopride2008
- Author(s)
  Ikoma Y, Watabe H, Hayashi T, Iida H
- Organizer
  Neuroreceptor Mapping 2008
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-20790839
[Presentation] Quantitative assessment of changes in binding potential with reference tissue model and multiple injection of [^<11>C]radopride2008
- Author(s)
  Ikoma Yoko
- Organizer
  Neuroreceptor Mapping 2008
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-20790839
[Presentation] [^<11>C]raclopride複数回投与によるPETを用いた受容体結合能変化の短時間測定2008
- Author(s)
  生駒洋子, 渡部浩司, 林拓也, 湊小太郎, 飯田秀博
- Organizer
  第48回日本核医学会
- Place of Presentation
  千葉
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20790839
[Presentation] [11C]racloprideを用いたドーパミンD2受容体測定における画像位置合わせ体動補正法の確立
- Author(s)
  生駒洋子，木村泰之，白石貴博，山谷泰賀，須原哲也，伊藤浩
- Organizer
  第52回日本核医学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] PET動態計測によるドーパミンD2受容体結合能の定量評価における画像位置合わせ体動補正法の検討
- Author(s)
  生駒洋子、木村泰之、白石貴博、須原哲也、伊藤浩
- Organizer
  第53回日本核医学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] Reproducibility of binding potential in a single PET scan with multiple injections of [11C]raclopride to evaluate dopamine release
- Author(s)
  Yoko Ikoma, Yasuyuki Kimura, Harumasa Takano, Hironobu Fujiwara, Fumitoshi Kodaka, Makiko Yamada, Tetsuya Suhara, Hiroshi Ito
- Organizer
  Society of Nuclear Medicine and Molecular Imaging
- Place of Presentation
  バンクーバー、カナダ
- Data Source
  KAKENHI-PROJECT-24791250
[Presentation] [11C]raclopride連続ボーラス投与法を用いたドーパミン放出量測定における安静時結合能の再現性の検討
- Author(s)
  生駒洋子、木村泰之、高野晴成、小高文聰、藤原広臨、山田真希子、須原哲也、伊藤浩
- Organizer
  第53回日本核医学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24791250

1. 小畠隆行 (00285107)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. ITO Hiroshi (20360357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. SUHARA Tetsuya (90216490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. TAKAHASHI Hidehiko (60415429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ikoma Yoko 生駒 洋子

IKOMA Yoko 生駒 洋子

Research Projects

Research Products

Co-Researchers

Quantitative evaluation of blood circulation using a machine learning generated blood input function in dynamic contrast-enhanced breast MRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Quantitative evaluation of blood circulation by deep learning in short time DCE-MRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mapping of tumor circulatory function using time course pattern in DCE-MRIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PET measurement of serotonin release in brain for investigation into effect of SSRI in depressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of shortened PET measurement method for investigation of the dopamine function in psychiatric disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of Normal Database of Neurotransmission System in the Human Brain using Positron emission tomography

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PETによる[^<11>C]DAA1106を用いた脳内活性型ミクログリアの非侵襲的定量Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 非侵襲・可視化技術ハンドブック-ナノ・バイオ・医療から情報システムまで-2007

Author(s)

Publisher

Description

Data Source

[Journal Article] Reference region extraction by clustering for the pharmacokinetic analysis of dynamic contrast-enhanced MRI in prostate cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative analysis for estimating billding potential of the peripheral benzodiazepine receptor with[11C]DAA11062007

Author(s)

Journal Title

Data Source

[Journal Article] Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [^<11>C]DAA11062007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [11C] DAA11062007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Quantitative analysis of 11C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Quantitative analyses of ^<18>F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain2006

Author(s)

Journal Title

Data Source

Ikoma Yoko 生駒洋子

IKOMA Yoko 生駒洋子