IGARASHI Shuichi 五十嵐修一

Researcher Number	60345519
External Links
Affiliation (based on the past Project Information) *help	2007: 新潟大, 医歯学総合病院, 講師 2004 – 2006: Niigata University, Medical and Dental Hospital, Lecture, 医歯学総合病院, 講師 2003: 新潟大学, 脳研究所, 助手
Review Section/Research Field	Principal Investigator Neurology / Biological Sciences Except Principal Investigator Neurology
Keywords	Principal Investigator SSBR / ataxia / EAOH / aprataxin / APTX / DNA repair / phosphatase / degeneration / exonuclease / DAN repair … More / cerebelllum / oxidative stress / XRCC 1 / SCA … More Except Principal Investigator poly(ADP-ribose)polymerase / XRCC1 / APTX / UPS / quantitative RT-PCR / regulatory T cell / lymphocyte subpopulation / immunological background / paraneoplastic neurological syndrome / 定量的PCR / 調節性T細胞 / リンパ球表面マーカー / 宿主要因 / 傍腫瘍性神経症候群 / DNA repair / CREB mediated transcription / spinocerebellar ataxia / polyglutamine / DNA修復 / CREB依存性転写 / 脊髄小脳変性症 / ポリグルタミン Less

アプラタキシン欠失による一本鎖核酸損傷修復障害と神経変性の関連についての解析Principal Investigator
- Principal Investigator
  
  五十嵐修一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Immunological background in paraneoplastic neurological syndrome and its therapeutic approach
- Principal Investigator
  
  TANAKA Keiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
中枢神経系におけるDNA修復機構障害と神経変性機構の解明Principal Investigator
- Principal Investigator
  
  五十嵐修一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Molecular mechanism of Neuronal cell death and transcriptional suppression associated with oxidative DNA stress.Principal Investigator
- Principal Investigator
  
  IGARASHI Shuichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
中枢神経系におけるDNA修復機構障害と神経変性機構の解明-アプラタキシン(APTX)の生理機能の検討-Principal Investigator
- Principal Investigator
  
  五十嵐修一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Transcriptional disturbance and Neurodegeneration.
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  NIIGATA UNIVERSITY

All 2007 2006 2005 2004

All Journal Article

[Journal Article] A case of Toxocara canis myelitis.2007
- Author(s)
  Ishihara T, Ozawa T, Nemoto M, Shinbo J, Igarashi S, Tanaka K, Nisizawa M.
- Journal Title
  
  Int Med 96(1)
  
  Pages: 141-143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590868
[Journal Article] New HSN2 mutation in Japanese patient with hereditary sensory and autonomic2006
- Author(s)
  Takagi M, Ozawa T, Hara K, Naruse S, Ishihara T, Shimbo J, Igarashi S, Tanaka K, Onodera 0, Nishizawa M.
- Journal Title
  
  neuropathy type 2. Neurology 66
  
  Pages: 1251-1252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590868
[Journal Article] Long-term therapeutic efficacy and safety of low-dose tacrolimus (FK506) for myasthenia gravis.2006
- Author(s)
  Tada M, Shimohata T, Tada M, Oyake M, Igarashi S, Onodera O, Naruse S, Tanaka K, Tsuji S, Nishizawa M.
- Journal Title
  
  J Neurol Sci 247
  
  Pages: 17-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590868
[Journal Article] A family with Charcot-Marie-Tooth disease type 4F (Periaxin mutation)2005
- Author(s)
  Shimohata M, Hirahara K, Igarashi S, Hara K, Kijima K, Onodera O, Tanaka K, Nishizawa M, Tsuji S, Hayasaka K.
- Journal Title
  
  Clin Neurol 45
  
  Pages: 221-225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590868
[Journal Article] Interference of CREB-dependent transcriptional activation by expanded polyglutamine stretches--augmentation of transcriptional activation as a potential therapeutic strategy for polyglutamine diseases.2005
- Author(s)
  Shimohata M, Shimohata M, Igarashi S, Naruse S, Tsuji S
- Journal Title
  
  J Neurochem 93(3)
  
  Pages: 654-663
- Data Source
  KAKENHI-PROJECT-16590817
[Journal Article] Selective silencing of a mutant transthyretin allele by small interfering RNAs.2005
- Author(s)
  Kurosawa T, Igarashi S, Nishizawa M, Onodera O
- Journal Title
  
  Biochem Biophys Res Commun. 25;337(3)
  
  Pages: 1012-1018
- Data Source
  KAKENHI-PROJECT-16590817
[Journal Article] The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.2004
- Author(s)
  Date H, Igarashi S, Sano Y, Takahashi T, Takahashi T, Takano H, Tsuji S, Nishizawa M, Onodera O.
- Journal Title
  
  Biochem Biophys Res Commun. 325(4)
  
  Pages: 1279-1285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.2004
- Author(s)
  Sano Y, Date H, Igarashi S, Onodera O, Oyake M, Takahashi T, Hayashi S, Morimatsu M, Takahashi H, Makifuchi T, Fukuhara N, Tsuji S.
- Journal Title
  
  Ann Neurol. 55(2)
  
  Pages: 241-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272

1. ONODERA Osamu (20303167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. OYAKE Mutsuo (70313559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. TANAKA Keiko (30217020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

IGARASHI Shuichi 五十嵐 修一

Research Projects

Research Products

Co-Researchers

アプラタキシン欠失による一本鎖核酸損傷修復障害と神経変性の関連についての解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological background in paraneoplastic neurological syndrome and its therapeutic approach

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

中枢神経系におけるDNA修復機構障害と神経変性機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of Neuronal cell death and transcriptional suppression associated with oxidative DNA stress.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

中枢神経系におけるDNA修復機構障害と神経変性機構の解明-アプラタキシン(APTX)の生理機能の検討-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transcriptional disturbance and Neurodegeneration.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A case of Toxocara canis myelitis.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] New HSN2 mutation in Japanese patient with hereditary sensory and autonomic2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Long-term therapeutic efficacy and safety of low-dose tacrolimus (FK506) for myasthenia gravis.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] A family with Charcot-Marie-Tooth disease type 4F (Periaxin mutation)2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Interference of CREB-dependent transcriptional activation by expanded polyglutamine stretches--augmentation of transcriptional activation as a potential therapeutic strategy for polyglutamine diseases.2005

Author(s)

Journal Title

Data Source

[Journal Article] Selective silencing of a mutant transthyretin allele by small interfering RNAs.2005

Author(s)

Journal Title

Data Source

[Journal Article] The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.2004

Author(s)

Journal Title

Description

Data Source

IGARASHI Shuichi 五十嵐修一