Ninomiya Itasu 二宮致

… Alternative Names

二宮致ニノミヤイタス

NINOMIYA Itasu 二宮致

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Researcher Number	60345618
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022: 金沢大学, 医学系, 協力研究員 2020: 金沢大学, 附属病院, 准教授 2016 – 2018: 金沢大学, 附属病院, 准教授 2012 – 2015: 金沢大学, 大学病院, 准教授 2010 – 2011: 金沢大学, 附属病院, 助教 … More 2008: Kanazawa University, 附属病院, 助教 2007: Kanazawa University, 医学部附属病院, 助教 2003: 金沢大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery
Keywords	Principal Investigator HDAC阻害剤 / バルプロ酸 / 食道癌 / Na+/H+交換輸送体5 / 遊走抑制効果 / 浸潤抑制効果 / 殺細胞活性 / UTX-143 / アミロライド / がん幹細胞 … More / 放射線照射 / 上皮間葉移行 / 放射線 / 上皮間葉転換 / ヒストン脱アセチル化阻害剤 / 放射線感受性 / 放射線耐性 / 放射線治療 / DNA二重鎖切断修復酵素 / ドセタキセル / DNA二重鎖切断 / 化学放射線療法 / 放射線治療学 / 微少転移 / 樹状細胞 / 微小転移 / リンパ節転移 / 胃癌 / 癌 / Na+/H+交換輸送体 / 大腸癌 … More Except Principal Investigator Function-preserving radical surgery / Navigation surgery / Rectal cancer / Early gastric cancer / Sentinel node / 食道癌 / 胃癌 / 縮小手術 / 機能温存根治手術 / ナビゲーションサージェリー / 直腸癌 / 早期胃癌 / センチネルリンパ節 Less

Development of a selective inhibitor against Na+/H+ exchange transporter 5 (NHE5), which is a target candidate molecule for gastrointestinal cancer.Principal Investigator
- Principal Investigator
  
  Ninomiya Itasu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kanazawa University
Development of novel colon cancer treatment by Na+/H+ exchanger inhibitorPrincipal Investigator
- Principal Investigator
  
  Ninomiya Itasu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Itasu Ninomiya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Effect of valproic acid and low dose docetaxel for radiosensitivity in esophageal squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  NINOMIYA Itasu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Evaluation of immune response and metastatic status in regional lymph nodes in patients with gastric carcinomaPrincipal Investigator
- Principal Investigator
  
  NINOMIYA Itasu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Extended application of sentinel node navigation surgery to gastric cancer
- Principal Investigator
  
  MIWA Koichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University

All 2016 2015 2012 2011 2008 2004 Other

All Journal Article Presentation

[Journal Article] Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells.2015
- Author(s)
  Makita N, Ninomiya I, Tsukada T, Okamoto K, Harada S, Nakanuma S, Sakai S, Makino I, Kinoshita J, Hayashi H, Oyama K, Nakagawara H, Miyashita T, Tajima H, Takamura H, Fushida S, Ohta T
- Journal Title
  
  Oncol Rep.
  
  Volume: 34(3) Issue: 3 Pages: 1185-1192
- DOI
  10.3892/or.2015.4089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430068, KAKENHI-PROJECT-25461909, KAKENHI-PROJECT-25462107
[Journal Article] Valproic acid,a histone deacetylase inhibitor,enhances radiosensitivity in esophageal squamous cell carcinoma2012
- Author(s)
  Shoji M
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 2140-2146
- DOI
  10.3892/ijo.2012.1416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249051, KAKENHI-PROJECT-22591380
[Journal Article] Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum2004
- Author(s)
  Ninomiya I, Fujimura T, Miwa K, et al.
- Journal Title
  
  Internatoinal Journal of Cancer 112・1
  
  Pages: 135-142
- Data Source
  KAKENHI-PROJECT-15390390
[Presentation] 食道癌細胞におけるvalproic acid の放射線照射後DNA二重鎖切断修復阻害効果2016
- Author(s)
  牧田直樹、二宮　致
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪（大阪府・大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-25461909
[Presentation] Valproic acid, a histone deacetylase inhibitor,enhances radiosensitivity in esophageal squamous cell carcinoma2012
- Author(s)
  Ninomiya I, Shoji M, Fujimura T
- Organizer
  International Symposium on Biochemistry & Biophysics
- Place of Presentation
  Sheraton ottawa hotel (Canada)
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] 他食道癌細胞に対するドセタキセルの放射線感受性増強効果2012
- Author(s)
  二宮致、宮永章平、藤村隆
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  Royton sapporo(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] バルプロ酸はヒストン脱アセチル化酵素阻害によって、食道癌細胞株の放射線感受性を増強させる2011
- Author(s)
  二宮致
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] 他バルプロ酸はヒストン脱アセチル化酵素阻害によって、食道癌細胞株の放射線感受性を増強させる2011
- Author(s)
  二宮致、正司正寿
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] 胃癌リンパ節転移による所属リンパ節内免疫応答の検討2008
- Author(s)
  中村慶史, 二宮致他
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591533
[Presentation] 胃癌リンパ節転移による所属リンパ節内免疫応答の検討2008
- Author(s)
  中村慶史, 二宮致, 他
- Organizer
  第67回日本癌学会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591533
[Presentation] 食道癌細胞におけるvalproic acidの上皮間葉転換抑制効果の検討
- Author(s)
  金本斐子、二宮致
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール（石川県金沢市）
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25461909
[Presentation] Valproic acid, a histone deacetylase inhibitor,enhances radiosensitivity in esophageal squamous cell carcinoma
- Author(s)
  Ninomiya I
- Organizer
  International Symposium on Biochemistry & Biophysics
- Place of Presentation
  Sheraton　Ottawa hotel（Canada）
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] 食道癌細胞に対するドセタキセルの放射線感受性増強効果
- Author(s)
  二宮　致
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  Royton sapporo(北海道）
- Data Source
  KAKENHI-PROJECT-22591380
[Presentation] 食道癌細胞におけるvalproic acid Epithelial to Mesenchymal Transition(EMT)とcancer stem like cell feature抑制効果の検討
- Author(s)
  金本斐子、二宮致
- Organizer
  第12回日本消化器外科学会大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25461909

1. FUJIMURA Takashi (50262580)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. 宇都義浩 (20304553)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 遠藤良夫 (30211783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OHTA Tetsuo (40194170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIWA Koichi (80019968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NISHIMURA Genichi (90208215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 滝野隆久 (40322119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 原田真市

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ninomiya Itasu 二宮 致

二宮 致 ニノミヤ イタス

NINOMIYA Itasu 二宮 致

Research Projects

Research Products

Co-Researchers

Development of a selective inhibitor against Na+/H+ exchange transporter 5 (NHE5), which is a target candidate molecule for gastrointestinal cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel colon cancer treatment by Na+/H+ exchanger inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Valproic acid inhibits irradiation-induced epithelial-mesenchymal transition and stem cell-like characteristics in esophageal squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of valproic acid and low dose docetaxel for radiosensitivity in esophageal squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of immune response and metastatic status in regional lymph nodes in patients with gastric carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Extended application of sentinel node navigation surgery to gastric cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Valproic acid,a histone deacetylase inhibitor,enhances radiosensitivity in esophageal squamous cell carcinoma2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-metastatic effect of capecitabine on human colon cancer xenografts in nude mouse rectum2004

Author(s)

Journal Title

Data Source

[Presentation] 食道癌細胞におけるvalproic acid の放射線照射後DNA二重鎖切断修復阻害効果2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Valproic acid, a histone deacetylase inhibitor,enhances radiosensitivity in esophageal squamous cell carcinoma2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 他 食道癌細胞に対するドセタキセルの放射線感受性増強効果2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] バルプロ酸はヒストン脱アセチル化酵素阻害によって、食道癌細胞株の放射線感受性を増強させる2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Ninomiya Itasu 二宮致

二宮致ニノミヤイタス

NINOMIYA Itasu 二宮致

[Presentation] 他食道癌細胞に対するドセタキセルの放射線感受性増強効果2012