Uzawa Hirotaka 鵜沢浩隆

… Alternative Names

Researcher Number	60356566 … More / 30656566 Less
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Affiliation (Current)	2021: 国立研究開発法人産業技術総合研究所, 材料・化学領域, 上級主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2019: 国立研究開発法人産業技術総合研究所, 材料・化学領域, 上級主任研究員 2015: 国立研究開発法人産業技術総合研究所, ナノ材料研究部門, 上級主任研究員 2015: 国立研究開発法人産業技術総合研究所, ナノシステム研究部門, 上級主任研究員 2012 – 2014: 独立行政法人産業技術総合研究所, ナノシステム研究部門, 上級主任研究員 2005 – 2006: 独立行政法人産業技術総合研究所, バイオニクス研究センター, 研究チーム長 2005 – 2006: 産業技術総合研究所, バイオニクス研究センター, チーム長 2004: 産業技術総合研究所, バイオニクス, チーム長
Review Section/Research Field	Principal Investigator Applied molecular and cellular biology / Basic Section 38040:Bioorganic chemistry-related Except Principal Investigator Social systems engineering/Safety system / Polymer chemistry
Keywords	Principal Investigator 糖鎖 / チップ / 有害蛋白質 / センシング / ベロ毒素 / 生体機能利用 / sugar / carbohydrate / Shiga toxins / chip … More Except Principal Investigator BSE / テロ対策 / 分子認識 / 機器分析 / 生物毒素 / 吸着 / グリコサミノグリカン / 糖鎖 / 硫酸化糖 / プリオン / ヘパラン硫酸 / グライコミクス / モジュール合成 / 糖鎖医薬 / ライブラリー合成 / 糖鎖モジュール化法 / アルツハイマー / 光反応性プローブ / モジュール化 / 糖鎖ライブラリー / glycosaminoglycans / module synthesis / sulfated sugars / prion / oligosaccharide / glycomics / heparan sulfate Less

クロストリジウム細菌生産毒素の分子認識機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  鵜沢浩隆
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Creation of molecular recognition tool against biological toxins and development of effective decontamination techniques
- Principal Investigator
  
  Seto Yasuo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Social systems engineering/Safety system
- Research Institution
  National Research Institute of Police Science
Development of carbohydrate chipsfor high-sensitive analysis targeting biohazard proteinsPrincipal Investigator
- Principal Investigator
  
  UZAWA Hirotaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  National Institute of Advanced Industrial Science and Technology (AIST)
Module Assembly and Evaluation of Artificial Glycosaminoglycans
- Principal Investigator
  
  NISHIDA Yoshihiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Polymer chemistry
- Research Institution
  Chiba University
  Nagoya University

All 2019 2013 2012 2007 2006 2005 2004

All Journal Article Presentation Book Patent

[Book] バイオセンサ・ケミカルセンサ事典「糖鎖」2007
- Author(s)
  鵜沢浩隆
- Publisher
  株式会社テクノシステム(近日刊行)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Silicon nitride sugar chips for detection of Ricinus communis proteins and Escherichia coli O157 Shiga toxins2019
- Author(s)
  Daiki Tanaka, Hirotaka Uzawa, Takehiro Nagatsuka, Yuki Oba, Atsunori Hiratsuka, Ken-ichi Tayama, Toshio Yoshida, Yasuo Seto, Hirofumi Dohi, Yoshihiro Nishida
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 580 Pages: 42-48
- DOI
  10.1016/j.ab.2019.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05469
[Journal Article] Glycotechnology for decontamination of biological agents : A model study using ricin and biotin-tagged synthetic glycopolymers2012
- Author(s)
  T. Nagatsuka, H. Uzawa, K. Sato, I. Ohsawa。Y. Seto and Y. Nishida
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 4 Pages: 832-837
- DOI
  10.1021/am201493q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310125
[Journal Article] Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and anlyasis of their interactions with lectins2007
- Author(s)
  X.Zeng, Sun H, J Liu, X iang, B Zhou, J.Uzawa
- Journal Title
  
  Carbohydrate Research (印刷中)
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Substrate specificity of N-acetylhexosaminidase from Aspergillus oryzae to artificial glycosyl acceptors having various substituents at the reducing ends2007
- Author(s)
  Makoto Ogata, Xiaoxiong Zeng, Taichi Usui, Hirotaka Uzawa
- Journal Title
  
  Carbohydrate Research 342
  
  Pages: 23-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and analysis of their interactions with lectins2007
- Author(s)
  Xiaoxiong Zeng, Yi Sun, Hong Ye, Jun Liu, Xiaoli Xiang, Bei Zhou, Hirotaka Uzawa
- Journal Title
  
  Carbohydrate Research 342
  
  Pages: 1244-1248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Synthesis of p -nitrophenyl sulfated disaccharides with β-D-(6-sulfo)-GlcNAc units using β- N -acetylhexosaminidase from Aspergillus oryzae in a transglycosylation reaction2007
- Author(s)
  Xiaoxiong Zeng, Yi Sun, Hong Ye, Jun Liu, Hirotaka Uzawa
- Journal Title
  
  Biotechnology Letters 29
  
  Pages: 1105-1110
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Synthesis of p-nitrophenyl sulfated disaccharides with B-D-(6-sulfo)-G1cNAc units using 6- N-acetylhexosaminidase from Aspergillus oryzae in a transglycosylation reaction2007
- Author(s)
  Xiaoxiong Zeng, Yi Sun, Hong Ye, Jun Liu, Hirotaka Uzawa
- Journal Title
  
  Biotechnology Letters 29
  
  Pages: 1105-1110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-O-sulfo-β-D-gluco- and galacto-pyranosyl linkages2006
- Author(s)
  Hirotaka Uzawa, Takehiro Nagatsuka, Hideo Hiramatsu, Yoshihiro Nishida
- Journal Title
  
  Chemical Communications (印刷中)
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-0-sulfo-β-D-gluco-and galacto-pyranosyl linkages2006
- Author(s)
  Hirotaka Uzawa, Takehiro Nagatsuka, Hideo Hiramatsu, Yoshihiro Nishida
- Journal Title
  
  Chemical Communications
  
  Pages: 1381-1383
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-O-sulfo-β-D-gluco- and galactopyranosyl linkages2006
- Author(s)
  H.Uzawa, T.Nagatsuka, H.Hiramatsu, Y.Nishida
- Journal Title
  
  Chemical Communication (印刷中)
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] A bovine glucuronidase for assembly of D-D-glucuronyl-(1-3)-6-O-sulfo-D-D-gluco- and galacto-pyranosyl linkages2006
- Author(s)
  Hirotaka Uzawa, Takehiro Nagatsuka, Hideo Hiramatsu, Yoshihiro Nishida
- Journal Title
  
  Chemical Communications
  
  Pages: 1381-1383
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] A bovine glucuronidase for assembly of beta-D-glucuronyl-(1-3)-6-O-sulfo-beta-D-gluco- and galactopyranosyl linkages2006
- Author(s)
  H.Uzawa, T.Nagatsuka, H.Hiramatsu, Y.Nishida
- Journal Title
  
  Chemical Communications.
  
  Pages: 1381-1383
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] 糖鎖で毒素を捕らえるテロ対策の新技術2006
- Author(s)
  鵜沢浩隆
- Journal Title
  
  化学 61
  
  Pages: 18-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] A bovine glucuronidase for assembly of beta-D-glucuronyl-(1-3)-6-O-sulfo-beta-D-gluco- and galactopyranosyl linkages2006
- Author(s)
  H.Uzawa, T.Nagatsuka, H.Hiramatsu, Y.Nishida
- Journal Title
  
  Chemical Communication
  
  Pages: 1381-1383
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] A bovine glucuronidase for assembly of beta-D-glucuronyl-(1-3)-6-0-sulfo-beta-D-gluco- and galactopyranosyl linkages2006
- Author(s)
  H.Uzawa, T.Natatsuka, H.Hiramatsu, Y.Nishida
- Journal Title
  
  Chemical Communication
  
  Pages: 1381-1383
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] Inhibition of PrP^<Sc> formation by synthetic O-sulfated glycopyranosides and their polymers2006
- Author(s)
  S.Yamaguchi, Y.Nishida, M.Kambara, C.-L.Kim, N.Ishiguro, T.Nagatsuka, H.Uzawa, M.Horiuchi
- Journal Title
  
  Biochem. Biophys. Res. Commun. 349
  
  Pages: 485-491
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] Synthesis of polyanionic glycopolymers for the facile assembly of glycosyl arrays2005
- Author(s)
  Hirotaka Uzawa, Hiroki Ito, Masayuki Izumi, Hideo Tokuhisa, Kazuhiro Taguchi, Norihiko Minoura
- Journal Title
  
  Tetrahedron 61
  
  Pages: 5895-5905
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Efficient Enzymatic Synthesis of 4-methylumbelliferyl N-acetyllactosaminide and 4-methylumbelliferyl sialyl N-acetyllactosaminides Employing β-D-galactosidase and Sialyltransferases2005
- Author(s)
  Xiaoxiong Zeng, Yi Sun, Hirotaka Uzawa
- Journal Title
  
  Biotechnology Letters 27
  
  Pages: 1461-1465
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Convenient enzymatic synthesis of a p-nitrophenyl oligosaccharide series of sialyl N-acetyllactosamine, sialyl Lex and relevant compounds2005
- Author(s)
  Xiaoxiong Zeng, Hirotaka Uzawa
- Journal Title
  
  Carbohydrate Research 340
  
  Pages: 2469-2475
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Convenient enzymatic synthesis of a p-nitrophenyl oligosaccharide series of sialyl N-acetyllactosamine, sialyl Le^x and relevant compounds2005
- Author(s)
  Xiaoxiong Zeng, Hirotaka Uzawa
- Journal Title
  
  Carbohydrate Research 340
  
  Pages: 2469-2475
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Efficient Enzymatic Synthesis of 4-methylumbelliferyl N-acetyllactosaminide and 4-methylumbelliferyl sialyl N-acetyllactosaminides Employing B-D-galactosidase and Sialyltransferases2005
- Author(s)
  Xiaoxiong Zeng, Yi Sun, Hirotaka Uzawa
- Journal Title
  
  Biotechnology Letters 27
  
  Pages: 1461-1465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Journal Article] Sulfatase-catalyzed assembly of regioselectively O-sulfated p-nitrophenyl α-D-gluco- and α-D-mannopyranosides2004
- Author(s)
  Uzawa, H., Nishida, Y.他4名
- Journal Title
  
  Carbohydrate. Research 339
  
  Pages: 1597-1602
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] Design of N-acetyl-6-sulfo-beta-D-glucosaminide based inhibitors of influenza virus sialidase2004
- Author(s)
  K.Sasaki, Y.Nishida, M.Kambara, H.Uzawa, T.Takahashi, T.Suzuki, Y.Suzuki, K.Kobayashi
- Journal Title
  
  Bioorg. Med. Chem. 12
  
  Pages: 1367-1375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] Sulfatase-catalyzed assembly of regioselectively O-sulfated p-nitrophenyl α-D-gluco- and α-D-mannopyranosides2004
- Author(s)
  Uzawa, H., Nishida, Y.他 4名
- Journal Title
  
  Carbohydrate.Research 339
  
  Pages: 1597-1602
- Data Source
  KAKENHI-PROJECT-16350063
[Journal Article] Sulfatase-catalyzed assembly of regioselectively O-sulfated p-nitrophenyl alpha-D-gluco- and alpha-D-mannonyranosides2004
- Author(s)
  H.Uzawa, Y.Nishida, K.Sasaki, T.Nagatsuka, H.Hiramatsu, K.Kobayashi
- Journal Title
  
  Carbohydr. Res. 339
  
  Pages: 1597-1602
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350063
[Patent] シアル酸含有3糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出2005
- Inventor(s)
  鵜沢浩隆, 曽暁雄
- Industrial Property Rights Holder
  産業技術総合研究所理事長
- Industrial Property Number
  2005-173183
- Filing Date
  2005-06-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Patent] 硫酸基含有糖化合物、それを用いるサーズウイルスまたはインフルエンザウイルスの検出2005
- Inventor(s)
  鵜沢浩隆, 曽暁雄
- Industrial Property Rights Holder
  産業技術総合研究所理事長
- Industrial Property Number
  2005-173184
- Filing Date
  2005-06-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380202
[Presentation] ケモエンザイム法による糖脂質ライブラリーの構築2019
- Author(s)
  鵜沢浩隆、平塚淳典
- Organizer
  第18回　産総研・産技連　LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-18K05469
[Presentation] Silicon Nitride Chips Modified with Gb3 Trisaccharide for Rapid Detection of Verotoxins2019
- Author(s)
  Hirotaka Uzawa, Atsunori Hiratsuka, Yasuo Seto, Ken-ichi Tayama, Toshio Yoshida, Yoshihiro Nishida
- Organizer
  10th International Conference on Molecular Electronics and Bioelectronics (M&BE10)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05469
[Presentation] DEVELOPMENT OF ON-SITE DECONTAMINATION TECHNOLOGIES – PHOTOCATALYTIC DEGRADATION FOR CHEMICAL WARFARE AGENTS AND MOLECULAR RECOGNITION ADSORPTION FOR BIOLOGICAL TOXINS2013
- Author(s)
  Yasuo Seto, Takeshi Ohmori, Mieko Kanamori-Kataoka, Kouichiro Tsuge, Isaac Ohsawa, Shintaro Kishi, Yuji Urushibata, Keita Sato, Asuka Komano, Hirotaka Uzawa, Takehiro Nagatsuka, Koji Takeuchi, Nobuaki Negishi, Tsutomu Hirakawa and Masahiro Furuno
- Organizer
  11th International symposium on Protection against Chemical and Biological Warfare agents
- Place of Presentation
  Stockholm
- Data Source
  KAKENHI-PROJECT-24310125

1. Seto Yasuo (10154668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. OHSAWA Isaku (30370886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. MIYAGUCHI Hajime (10370884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NISHIDA Yoshihiro (80183896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. MIURA Yoshiko (00335069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HORIUCHI Motohiro (30219216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. UZAWA Hirotaka (30656566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IZUMI Masayuki (80332641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 柘浩一郎 (90356204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小林一清 (10023483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 平塚淳典 (70392652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Uzawa Hirotaka 鵜沢 浩隆

鵜沢 浩隆 ウザワ ヒロタカ

UZAWA Hirotaka 鵜沢 浩隆

Research Projects

Research Products

Co-Researchers

クロストリジウム細菌生産毒素の分子認識機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of molecular recognition tool against biological toxins and development of effective decontamination techniques

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of carbohydrate chipsfor high-sensitive analysis targeting biohazard proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Module Assembly and Evaluation of Artificial Glycosaminoglycans

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] バイオセンサ・ケミカルセンサ事典 「糖鎖」2007

Author(s)

Publisher

Description

Data Source

[Journal Article] Silicon nitride sugar chips for detection of Ricinus communis proteins and Escherichia coli O157 Shiga toxins2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycotechnology for decontamination of biological agents : A model study using ricin and biotin-tagged synthetic glycopolymers2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and anlyasis of their interactions with lectins2007

Author(s)

Journal Title

Data Source

[Journal Article] Substrate specificity of N-acetylhexosaminidase from Aspergillus oryzae to artificial glycosyl acceptors having various substituents at the reducing ends2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effective chemoenzymatic synthesis of p-aminophenyl glycosides of sialyl N-acetyllactosaminide and analysis of their interactions with lectins2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Synthesis of p -nitrophenyl sulfated disaccharides with β-D-(6-sulfo)-GlcNAc units using β- N -acetylhexosaminidase from Aspergillus oryzae in a transglycosylation reaction2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Synthesis of p-nitrophenyl sulfated disaccharides with B-D-(6-sulfo)-G1cNAc units using 6- N-acetylhexosaminidase from Aspergillus oryzae in a transglycosylation reaction2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-O-sulfo-β-D-gluco- and galacto-pyranosyl linkages2006

Author(s)

Journal Title

Data Source

[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-0-sulfo-β-D-gluco-and galacto-pyranosyl linkages2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] A bovine glucuronidase for assembly of β-D-glucuronyl-(1-3)-6-O-sulfo-β-D-gluco- and galactopyranosyl linkages2006

Author(s)

Uzawa Hirotaka 鵜沢浩隆

鵜沢浩隆ウザワヒロタカ

UZAWA Hirotaka 鵜沢浩隆

[Book] バイオセンサ・ケミカルセンサ事典「糖鎖」2007