Hayashi Kanehiro 林周宏

Researcher Number	60373354
Other IDs
Affiliation (Current)	2020: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2016 – 2018: 慶應義塾大学, 医学部(信濃町), 講師 2015: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Basic Section 48010:Anatomy-related
Keywords	Principal Investigator 発生 / 大脳新皮質 / 層構造 / 細胞凝集 / 細胞接着 / Reelin / N-cadherin / 神経細胞凝集 / リーリン / Dbnl

発生期にリーリンにより誘導される神経細胞凝集は大脳新皮質層構造の起点となるか？Principal InvestigatorOngoing
- Principal Investigator
  
  林周宏
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Keio University
Molecular mechanism of Reelin-induced neuronal aggregation in the developing mouse cereberal cortexPrincipal Investigator
- Principal Investigator
  
  Hayashi Kanehiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Keio University

All 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Encyclopedia of Signaling Molecules second edition 'Reelin'2018
- Author(s)
  Hayashi K, Inoue S, Nakajima K
- Publisher
  Springer International Publishing
- ISBN
  9783319672007
- Data Source
  KAKENHI-PROJECT-15K06745
[Journal Article] Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex.2019
- Author(s)
  Inoue Seika、Hayashi Kanehiro、Fujita Kyota、Tagawa Kazuhiko、Okazawa Hitoshi、Kubo Ken-ichiro、Nakajima Kazunori
- Journal Title
  
  J Neurosci.
  
  Volume: 39 Pages: 678-691
- DOI
  10.1523/jneurosci.1634-18.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06842, KAKENHI-PROJECT-18K07855, KAKENHI-PROJECT-18K19379, KAKENHI-PROJECT-15H02355, KAKENHI-PROJECT-16K07040
[Journal Article] Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex.2019
- Author(s)
  Shin Minkyung、Kitazawa Ayako、Yoshinaga Satoshi、Hayashi Kanehiro、Hirata Yukio、Dehay Colette、Kubo Ken‐ichiro、Nakajima Kazunori
- Journal Title
  
  J Comp Neurol.
  
  Volume: 527 Pages: 1577-1597
- DOI
  10.1002/cne.24634
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06842, KAKENHI-PROJECT-18K07855, KAKENHI-PROJECT-18K19379, KAKENHI-PROJECT-15H02355
[Journal Article] The brain-specific RasGEF very-KIND is required for normal dendritic growth in dcerebellar granule cells and proper motor coordination.2017
- Author(s)
  Hayashi K, Furuya A, Sakamaki Y, Akagi T, Shinoda Y, Sadakata T, Hashikawa T, Shimizu K, Minami H, Sano Y, Nakayama M, and Furuichi T.
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0173175
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290026, KAKENHI-PROJECT-15K14356, KAKENHI-PROJECT-15K21013, KAKENHI-PROJECT-15K06745, KAKENHI-PROJECT-15K08192, KAKENHI-PROJECT-17H03563
[Journal Article] Reelin transiently promotes N-cadherin?dependent neuronal adhesion during mouse cortical development2017
- Author(s)
  Yuki Matsunaga, Mariko Noda, Hideki Murakawa, Kanehiro Hayashi, Arata Nagasaka, Seika Inoue, Takaki Miyata, Takashi Miura, Ken-ichiro Kubo, and Kazunori Nakajima
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A.
  
  Volume: 114 Pages: 2048-2053
- DOI
  10.1073/pnas.1615215114
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01293, KAKENHI-PLANNED-16H06482, KAKENHI-PROJECT-15H02355, KAKENHI-PROJECT-15H03635, KAKENHI-PROJECT-16J05704, KAKENHI-PROJECT-26287025, KAKENHI-PROJECT-26400205, KAKENHI-PROJECT-15K06745, KAKENHI-PROJECT-15K09723, KAKENHI-PROJECT-26430075, KAKENHI-PROJECT-17K16315, KAKENHI-PROJECT-16H02457
[Journal Article] The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon- derived GABAergic neurons in the developing mouse brain.2015
- Author(s)
  Shigeaki Kanatani, Takao Honda, Michihiko Aramaki, Kanehiro Hayashi, Ken-ichiro Kubo, Mami Ishida, Daisuke H. Tanaka, Takeshi Kawauchi, Katsutoshi Sekine, Sayaka Kusuzawa, Takahiko Kawasaki, Tatsumi Hirata, Hidenori Tabata, Per Uhlen and Kazunori Nakajima
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112(36)
- DOI
  10.1073/pnas.1420701112
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06745, KAKENHI-PROJECT-15K06746, KAKENHI-PROJECT-25430046, KAKENHI-PROJECT-26430075, KAKENHI-PROJECT-15K14323, KAKENHI-PUBLICLY-25123727, KAKENHI-PUBLICLY-15H01293, KAKENHI-PUBLICLY-15H01453, KAKENHI-ORGANIZER-22111001, KAKENHI-PUBLICLY-26110718, KAKENHI-PROJECT-25430045, KAKENHI-PROJECT-24700357, KAKENHI-PROJECT-25290010, KAKENHI-PROJECT-26290015, KAKENHI-PROJECT-15H02355
[Journal Article] Cellular dynamics of neuronal migration in the hippocampus2015
- Author(s)
  Hayashi K, Kubo K, Kitazawa A and Nakajima K
- Journal Title
  
  Front Neurosci.
  
  Volume: in press Pages: 135-135
- DOI
  10.3389/fnins.2015.00135
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111004, KAKENHI-PROJECT-15K06745, KAKENHI-PROJECT-26430075, KAKENHI-PROJECT-15K18363, KAKENHI-PUBLICLY-15H01293, KAKENHI-PROJECT-15H02355
[Presentation] 発生中の大脳新皮質において辺縁帯直下に認める比較的未成熟な神経細胞の凝集構造についての知見2019
- Author(s)
  久保健一郎、シンミンギョン、北澤彩子、吉永怜史、林周宏、仲嶋一範
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] 異所移植による発生期のマウス海馬CA1及び大脳新皮質の移動についての解析2019
- Author(s)
  北澤彩子、シンミンギョン、林周宏、久保健一郎、仲嶋一範
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing mouse cerebral neocortex2018
- Author(s)
  Seika Inoue, Kanehiro Hayashi, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Ken-ichiro Kubo, and Kazunori Nakajima
- Organizer
  2018 The American Society for Cell Biology (ASCB) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] Reelin-DBNL signaling regulates neuronal migration via N-cadherin/α-N-catenin complex in the intermediate zone and multipolar cell accumulation zone of the developing mouse cerebral neocortex2018
- Author(s)
  Seika Inoue, Kanehiro Hayashi, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Ken-ichiro Kubo, and Kazunori Nakajima
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会合同年会
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] Reelin controls N-cadherin-dependent neuronal adhesion by a couple of mechanisms in the developing mouse cortex2018
- Author(s)
  Kanehiro Hayashi, Nobuhiko Nakao, Seika Inoue, Taiji Adachi, Ken-ichiro Kubo, and Kazunori Nakajima
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会合同年会
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] 発生期哺乳類大脳皮質における神経細胞移動は癌細胞の間葉上皮転換と同じ仕組みを持つか？2018
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第37回分子病理学研究会はがくれシンポジウム
- Data Source
  KAKENHI-PROJECT-18K06842
[Presentation] マウス大脳新皮質形成におけるreelin-Nck2シグナルの役割2017
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第40回日本分子生物学会年会・第90回日本生化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Molecular mechanisms of Reelin-induced neuronal aggregation in the developing mouse neocortex2017
- Author(s)
  Inoue S, Hayashi K, Kubo KI, and Nakajima K
- Organizer
  18th International Congress of Developmental Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Molecular mechanisms of neuronal aggregation caused by Reelin in the developing mouse neocortex2017
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] The Role of Nck as a downstream effector of the Reelin signaling2017
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Region-dependent differences in the migratory capacity of hippocampal CA1 and neocortical neurons during brain development2017
- Author(s)
  北澤彩子、シンミンギョン、林周宏、久保健一郎、仲嶋一範
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Structural analyses of radial glial fibers in the developing reeler neocortex2017
- Author(s)
  Shin MK, Kitazawa A, Matsunaga Y, Hayashi K, Kubo KI, and Nakajima K.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] マウス大脳新皮質発生におけるReelin-Nckシグナル経路の役割2016
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Investigation of the molecular mechanisms that regulate Reelin-induced neuronal aggregation in the mouse neocortex2016
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Analysis of Reelin-Nck signaling in mouse neocortex2016
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Investigation of the molecular mechanisms underlying Reelin-induced neuronal aggregation in the mouse neocortex2016
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  2016 The American Society for Cell Biology (ASCB) Annual Meeting
- Place of Presentation
  サンフランシスコ(アメリカ)
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] 大脳新皮質においてリーリン分子により誘導される神経細胞凝集を担うシグナル伝達経路の探索”2016
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Analysis of the molecular mechanisms that underlie Reelin-induced neuronal aggregation in the mouse neocortex2016
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  第９回神経発生討論会・難治疾患共同研究拠点共同開催学術集会
- Place of Presentation
  東京医科歯科大学(東京都文京区)
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] 大脳新皮質においてリーリン分子により引き起こされる神経細胞凝集のシグナル伝達経路の探索2016
- Author(s)
  井上聖香、林周宏、久保健一郎、仲嶋一範
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Function of the Reelin-Nck signaling pathway during mouse neocortical development2016
- Author(s)
  林周宏、井上聖香、久保健一郎、仲嶋一範
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K06745
[Presentation] Morphological analyses of radial glial cells in the developing mouse neocortex2016
- Author(s)
  シン・ミンギョン、北澤彩子、松永友貴、林周宏、久保健一郎、仲嶋一範
- Organizer
  Society for Neuroscience, Neuroscience 2016 meeting
- Place of Presentation
  サンディエゴ(アメリカ)
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06745

1. Inoue Seika

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
2. KUBO Ken-Ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
3. OKAZAWA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. FUJITA Keita

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SHINODA Yo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MURAKAWA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. MATSUNAGA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NODA Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 仲嶋一範

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
10. 田川一彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 本田岳夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田畑秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 平田たつみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 川内健史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 川崎能彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 古市貞一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 佐野良威

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 林茂生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 北澤彩子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井上健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 宮田卓樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Kanehiro 林 周宏

Research Projects

Research Products

Co-Researchers

発生期にリーリンにより誘導される神経細胞凝集は大脳新皮質層構造の起点となるか？Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of Reelin-induced neuronal aggregation in the developing mouse cereberal cortexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Encyclopedia of Signaling Molecules second edition 'Reelin'2018

Author(s)

Publisher

ISBN

Data Source

[Journal Article] Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Both excitatory and inhibitory neurons transiently form clusters at the outermost region of the developing mammalian cerebral neocortex.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The brain-specific RasGEF very-KIND is required for normal dendritic growth in dcerebellar granule cells and proper motor coordination.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reelin transiently promotes N-cadherin?dependent neuronal adhesion during mouse cortical development2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon- derived GABAergic neurons in the developing mouse brain.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular dynamics of neuronal migration in the hippocampus2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 発生中の大脳新皮質において辺縁帯直下に認める比較的未成熟な神経細胞の凝集構造についての知見2019

Author(s)

Organizer

Data Source

[Presentation] 異所移植による発生期のマウス海馬CA1及び大脳新皮質の移動についての解析2019

Author(s)

Organizer

Data Source

[Presentation] Drebrin-like (Dbnl) controls neuronal migration via regulating N-cadherin expression in the developing mouse cerebral neocortex2018

Author(s)

Organizer

Data Source

[Presentation] Reelin-DBNL signaling regulates neuronal migration via N-cadherin/α-N-catenin complex in the intermediate zone and multipolar cell accumulation zone of the developing mouse cerebral neocortex2018

Author(s)

Organizer

Data Source

[Presentation] Reelin controls N-cadherin-dependent neuronal adhesion by a couple of mechanisms in the developing mouse cortex2018

Author(s)

Organizer

Data Source

[Presentation] 発生期哺乳類大脳皮質における神経細胞移動は癌細胞の間葉上皮転換と同じ仕組みを持つか？2018

Author(s)

Organizer

Data Source

[Presentation] マウス大脳新皮質形成におけるreelin-Nck2シグナルの役割2017

Author(s)

Organizer

Data Source

[Presentation] Molecular mechanisms of Reelin-induced neuronal aggregation in the developing mouse neocortex2017

Hayashi Kanehiro 林周宏