WAKITA Ryo 脇田亮

… Alternative Names

脇田亮ワキタリョウ

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Researcher Number	60376712
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2015: 東京医科歯科大学, 医歯学総合研究科(歯), 准教授 2014 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2009 – 2012: Tokyo Medical and Dental University, 歯学部附属病院, 助教 2008 – 2009: Tokyo Medical and Dental University, 歯学部・附属病院, 助教 2007: Tokyo Medical and Dental University, 歯学部附属病院, 助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related / Surgical dentistry
Keywords	Principal Investigator カルシウムイオン / 気管支平滑筋 / カルシウムチャネル / フィトケミカル / 局所麻酔 / リドカイン / イオントフォレーシス / 代替医療 / 喘息 / 甘草 … More / 気管支喘息 / 気管上皮 / kushenol / Trifolrhizin / Caチャンネル / ホスホキナーゼ / trifolirhizin / 漢方薬 / duty cycle / 無痛 / マイクロダイアリシス / 交流 / 歯科麻酔学 / イオンとフォレーシス / von Frey test / エピネフリン … More Except Principal Investigator 喘息 / 細胞増殖 / 気管支平滑筋 / 気管支喘息 / 炎症性副作用 / ビスホスホネート / ぜんそく / 血小板 / タキキニン受容体 / Neurokinin receptor / AC-IOP / アルギン酸ゲル / リドカイン / 浸透効率 / 矩形波 / 交流通電 / イオントフォレーシス Less

甘草由来フィトケミカルによる気管支調節機構の分子機序解明Principal Investigator
- Principal Investigator
  
  脇田亮
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
ビスホスホネートの投与経路による細胞内取込機構解明と副作用を克服した投与法の開発
- Principal Investigator
  
  船山ひろみ
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tsurumi University
Regulatory Mechanisms of Bronchial Asthma and Tracheal Epithelial Stabilization by PhytochemicalsPrincipal Investigator
- Principal Investigator
  
  Wakita Ryo
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
The role of platelets in the mechanism of pathogenesis of bronchial asthma
- Principal Investigator
  
  Funayama Hiromi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tsurumi University
Airway smooth muscle relaxation by crosstalk with tracheal epitheliumPrincipal Investigator
- Principal Investigator
  
  Wakita Ryo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
Neurokinin receptor signaling in Asthma
- Principal Investigator
  
  FUNAYAMA Hiromi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tsurumi University
The new painless local application of antibiotics by use of iontophoresis with alternative currentPrincipal Investigator
- Principal Investigator
  
  WAKITA Ryo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
Lidocaine iontophoresis using alternating current Development of the device for patient controlled analgesia-
- Principal Investigator
  
  ANDO Shizuka
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
The anesthetic effect at lidocaine iontophoresis using alternating currents with duty cyclePrincipal Investigator
- Principal Investigator
  
  WAKITA Ryo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University

All 2022 2019 2018 2017 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] pH-Responsive Release of Anesthetic Lidocaine Derivative QX-OH from Mesoporous Silica Nanoparticles Mediated by Ester Bonds2022
- Author(s)
  Takahashi Ken、Nakagawa Yasuhiro、Sato Yu、Wakita Ryo、Maeda Shigeru、Ikoma Toshiyuki
- Journal Title
  
  SSRN Electronic Journal
  
  Volume: 78 Pages: 103977-103977
- DOI
  10.2139/ssrn.4183237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10108
[Journal Article] Effects of Zoledronate on Local and Systemic Production of IL-1β, IL-18, and TNF-α in Mice and Augmentation by Lipopolysaccharide2019
- Author(s)
  Funayama Hiromi、Tashima Itaru、Okada Satoru、Ogawa Takuya、Yagi Hideki、Tada Hiroyuki、Wakita Ryo、Asada Yoshinobu、Endo Yasuo
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 6 Pages: 929-936
- DOI
  10.1248/bpb.b18-00923
- NAID
  130007657675
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11899, KAKENHI-PROJECT-17K11976, KAKENHI-PROJECT-19K07171, KAKENHI-PROJECT-16K08409
[Journal Article] Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility.2014
- Author(s)
  Bernstein K, Vink JY, Fu XW, Wakita H, Danielsson J, Wapner R, Gallos G.
- Journal Title
  
  Am J Obstet Gynecol.
  
  Volume: 211 Issue: 6 Pages: 688.e1-688.e10
- DOI
  10.1016/j.ajog.2014.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463203
[Journal Article] In vitro evaluation of calcium alginate gels as matrix for iontophoresis electrodes2012
- Author(s)
  Haida H, Ando S, Ogami S, Wakita R, Kohase H, Saito N, Yoshioka T, Ikoma T, Tanaka J, Umino M, and Fukayama H
- Journal Title
  
  Journal of Medical and Dental Sciences
  
  Volume: 59(1) Pages: 9-16
- NAID
  130006943990
- Data Source
  KAKENHI-PROJECT-22791958
[Journal Article] The relation between the duty cycle and anesthetic effect in lidocaine iontophoresis using alternating current2011
- Author(s)
  Wakita R, Nakajima A, Haida Y, Umino M, Fukayama H
- Journal Title
  
  Pain Practice
  
  Volume: 11(3) Pages: 261-6
- Data Source
  KAKENHI-PROJECT-22791958
[Journal Article] The relation between epinephrine concentration and anesthetic effect at lidocaine iontonhoresis2009
- Author(s)
  Ryo Wakita, Yuka Ohno, Saori Ohgami, Shizuka Hayashi, Masahiro Umino
- Journal Title
  
  Pain Practice 9
  
  Pages: 115-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791488
[Journal Article] The relation between epinephrine concentration and the anesthetic effect of lidocaine iontophoresis.2009
- Author(s)
  Wakita R, Oono Y, Oogami S, Hayashi S, Umino M.
- Journal Title
  
  Pain Practice 9(2)
  
  Pages: 115-21
- Data Source
  KAKENHI-PROJECT-19791488
[Patent] イオントフォレシス用電極組成物2010
- Inventor(s)
  田中順三、吉岡朋彦、征矢大、海野雅浩、脇田亮、安藤寧
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Patent Publication Number
  2010-137048
- Acquisition Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21791979
[Patent] イオントフォレシス用電極組成物2009
- Inventor(s)
  脇田亮、林寧、海野雅浩、田中順三、吉岡朋彦、征矢大
- Industrial Property Rights Holder
  脇田亮、林寧、海野雅浩、田中順三、吉岡朋彦、征矢大
- Industrial Property Number
  2009-260161
- Filing Date
  2009-11-13
- Acquisition Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] Iontophoretic administration of bisphosphonates: a trial for establishing a method to prevent their side effects and to retain their potent anti-bone resorptive effects2018
- Author(s)
  Hiromi Funayama, Takaaki Munemasa, Ryo Wakita, Haruhisa Fukayama, Yasuo Endo, Yoshinobu Asada
- Organizer
  11th Biennial Conference of the Pediatric Dentistry Association of Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11976
[Presentation] 生姜辛味成分による気管支拡張作用の分子機序解明2017
- Author(s)
  脇田　亮
- Organizer
  第25回スパイス＆ハーブ研究成果セミナー
- Place of Presentation
  学士会館（東京都千代田区）
- Invited
- Data Source
  KAKENHI-PROJECT-26463058
[Presentation] Selective Pharmacologic Targeting of the GABAA α4 Subunit in Airway Smooth Muscle to Alleviate Bronchospasm.2015
- Author(s)
  Gene T. Yocum, Ryo Wakita, Michael R Stephen, James M. Cook, Charles W. Emala, George Gallos
- Organizer
  AUA 62nd Annual Meeting
- Place of Presentation
  Nashville, TN, USA
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26463058
[Presentation] Selective Pharmacologic Targeting of the GABAA α4 Subunit in Airway Smooth Muscle to Alleviate Bronchospasm2015
- Author(s)
  GT. Yocum, R Wakita, MR Stephen, JM. Cook, CW. Emala, G Gallos
- Organizer
  AUA 62nd Annual Meeting
- Place of Presentation
  Nashville, TN, USA
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-26463058
[Presentation] THE EFFICACY OF IONTOPHORESIS USING THE BIPOLAR SQUARE WAVE WITH DUTY CYCLE2011
- Author(s)
  R.Wakita, A.Nakajima, H.Haida, H.Fukayama
- Organizer
  the 30th Annual ESRA Congress
- Place of Presentation
  Dresden, Germany
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] THE EFFICACY OF IONTOPHORESIS USING THE BIPOLAR SQUARE WAVE WITH DUTYCYCLE2011
- Author(s)
  R. Wakita, A. Nakajima, H. Haida, H. Fukayama
- Organizer
  the 30th Annual ESRA Congress
- Place of Presentation
  Germany
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] 交流イオントフォレーシスを用いたリドカイン送達における波形の影響2010
- Author(s)
  中島淳, 脇田亮, 灰田悠, 安藤寧, 深山治久
- Organizer
  第38回日本歯科麻酔学会総会
- Place of Presentation
  横須賀、神奈川
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] 交流イオントフォレーシスを用いたリドカイン送達における波形の影響2010
- Author(s)
  中島淳、脇田亮、灰田悠、安藤寧、深山治久
- Organizer
  第38回日本歯科麻酔学会
- Place of Presentation
  横須賀芸術劇場(神奈川県)
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21791979
[Presentation] 交流イオントフォレーシスを用いたリドカイン送達における波形の影響2010
- Author(s)
  中島淳、脇田亮、灰田悠、安藤寧、深山治久
- Organizer
  第38回日本歯科麻酔学会
- Place of Presentation
  横須賀
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21791979
[Presentation] Electrochemical Deposition of Alginic Acid on Metal Surfaces for the Development of Iontophoresis Electrode2010
- Author(s)
  N.Saito, T.Yoshioka, T.Ikoma, N.Ohashi, H.Haida, S.Ogami, R.Wakita, H.Kohase, M.Umino, J.Tanaka
- Organizer
  Fourth international conference on the science and technology for advanced ceramics (STAC-4)
- Place of Presentation
  横浜、神奈川
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] Electrochemical Deposition of Alginic Acid on Metal Surfaces for theDevelopment of Iontophoresis Electrode2010
- Author(s)
  N. Saito, T. Yoshioka, T. Ikoma, N.Ohashi, H. Haida, S. Ogami, R. Wakita, H. Kohase, M.Umino and J. Tanaka
- Organizer
  Fourth international conference on the science and technology for advanced ceramics (STAC-4)
- Place of Presentation
  神奈川
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] 交流イオントフォレーシスを用いたリドカイン送達における波形の影響2010
- Author(s)
  中島淳,脇田亮,灰田悠,安藤寧,深山治久
- Organizer
  第38回日本歯科麻酔学会総会
- Place of Presentation
  神奈川
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22791958
[Presentation] リドカイン担持アルギン酸電極を用いた交流イオントフォレーシスの有用性の検討2009
- Author(s)
  灰田悠, 大上沙央理, 脇田亮, 海野雅浩, 吉岡朋彦, 田中順三, 小長谷光
- Organizer
  日本歯科麻酔学会総会
- Place of Presentation
  愛知県名古屋
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] リドカイン担持アルギン酸電極を用いた交流イオントフォレーシスの有用性の検討.2009
- Author(s)
  灰田悠, 大上沙央理, 脇田亮, 海野雅浩, 吉岡朋彦, 田中順三, 小長谷光
- Organizer
  第37回日本歯科麻酔学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] リドカイン担持アルギン酸電極を用いた交流イオントフォレーシスの有用性の検討2009
- Author(s)
  灰田悠, 大上沙央理, 脇田亮, 安藤寧, 海野雅浩, 吉岡朋彦, 田中順三, 小長谷光
- Organizer
  第37回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21791979
[Presentation] リドカイン担持アルギン酸電極を用いた交流イオントフォレーシス-移送効率と電圧との関係-2009
- Author(s)
  灰田悠、大上沙央理、安藤寧、脇田亮、小長谷光、斎藤典生、吉岡朋彦、田中順三、海野雅浩
- Organizer
  第2回医歯工学イノベーションシンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21791979
[Presentation] リドカイン担持アルギン酸電極を用いた交流イオントフォレーシス-移送効率と電圧との関係-2009
- Author(s)
  灰田悠、大上沙央理、安藤寧、脇田亮、小長谷光、斎藤典生、吉岡朋彦、田中順三、海野雅浩
- Organizer
  第2回医歯工学イノベーション・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21791979
[Presentation] 交流イオントフォレーシスを用いた局所麻酔薬の送達2008
- Author(s)
  脇田亮・林寧・芝地貴夫・海野雅浩
- Organizer
  日本歯科麻酔学会総会
- Place of Presentation
  大阪府吹田
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] 矩形波交流通電drug delivery装置の試作.2008
- Author(s)
  林寧, 脇田亮, 芝地貴夫, 海野雅浩
- Organizer
  第36回日本歯科麻酔学会総会
- Place of Presentation
  大阪
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] 矩形波交流通電drug delivery装置を用いた局所麻酔薬の送達.2008
- Author(s)
  脇田亮, 林寧, 芝地貴夫, 海野雅浩
- Organizer
  第36回日本歯科麻酔学会総会
- Place of Presentation
  大阪
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] イオントフォレーシスによる局所麻酔薬の送達〜血管収縮薬添加の影響〜2007
- Author(s)
  脇田亮, 他
- Organizer
  日本臨床麻酔学会
- Place of Presentation
  東京都
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] イオントフォレーシスによる皮下への局所麻酔薬の送達. 血管収縮薬添加の影響.2007
- Author(s)
  脇田亮, 林寧, 大上沙央理, 海野雅浩
- Organizer
  第27回日本臨床麻酔学会誌
- Place of Presentation
  東京
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19791488
[Presentation] 副作用軽減を目的とするイオントフォレーシスを用いたビスフォスフォネート製剤の新しい投与方法．
- Author(s)
  船山ひろみ, 宗正隆明, 脇田亮, 深山治久, 朝田芳信．
- Organizer
  第52回日本小児歯科学会大会
- Place of Presentation
  きゅりあん（東京都、品川区）
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25463203

1. FUNAYAMA Hiromi (00359530)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
2. ANDO Shizuka (20516306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. UMINO Masahiro (90014125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. ENDO Yasuo (50005039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 生駒俊之 (20370306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. FUKAYAMA Haruhisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

WAKITA Ryo 脇田 亮

脇田 亮 ワキタ リョウ

Research Projects

Research Products

Co-Researchers

甘草由来フィトケミカルによる気管支調節機構の分子機序解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビスホスホネートの投与経路による細胞内取込機構解明と副作用を克服した投与法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory Mechanisms of Bronchial Asthma and Tracheal Epithelial Stabilization by PhytochemicalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of platelets in the mechanism of pathogenesis of bronchial asthma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Airway smooth muscle relaxation by crosstalk with tracheal epitheliumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neurokinin receptor signaling in Asthma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The new painless local application of antibiotics by use of iontophoresis with alternative currentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lidocaine iontophoresis using alternating current Development of the device for patient controlled analgesia-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The anesthetic effect at lidocaine iontophoresis using alternating currents with duty cyclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] pH-Responsive Release of Anesthetic Lidocaine Derivative QX-OH from Mesoporous Silica Nanoparticles Mediated by Ester Bonds2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Zoledronate on Local and Systemic Production of IL-1β, IL-18, and TNF-α in Mice and Augmentation by Lipopolysaccharide2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro evaluation of calcium alginate gels as matrix for iontophoresis electrodes2012

Author(s)

WAKITA Ryo 脇田亮

脇田亮ワキタリョウ