sakai norihiko 坂井宣彦

… Alternative Names

SAKAI NORIHIKO 坂井宣彦

坂井宣彦サカイノリヒコ

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Researcher Number	60377421
Other IDs
External Links
Affiliation (Current)	2022: 金沢大学, 附属病院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 金沢大学, 附属病院, 准教授 2016 – 2018: 金沢大学, 附属病院, 助教 2014 – 2015: 金沢大学, 大学病院, 助教 2010: Kanazawa University, 大学病院, 助教 2009: Kanazawa University, 附属病院, 助教
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Complex systems / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 線維化 / 慢性腎臓病 / 腎臓 / エピジェネティクス / Fibrocyte / ケモカイン / ヒストンアセチル化 / クルクミン / NF-κB / LPA１ / LPA / LPA1 / 腎不全 … More Except Principal Investigator … More 腎臓病 / 慢性炎症 / 感染症 / 細菌 / ゲノム / シングルセル / 腎臓 / 糖尿病性腎症 / 糖尿病性腎臓病 / キラルアミノ酸 / バイオマーカー Less

線維化組織微小環境の制御による慢性腎臓病進展機序の解明と臨床応用Principal Investigator
- Principal Investigator
  
  坂井宣彦
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kanazawa University
キラルアミノ酸による糖尿病性腎症の病態解明と新規バイオマーカー開発
- Principal Investigator
  
  和田隆志
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kanazawa University
Involvement of cytoskeleton-dependent signaling in renal fibrosisPrincipal Investigator
- Principal Investigator
  
  Sakai Norihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa University
Inflammation and related molecular preventive medicine in kidney diseases
- Principal Investigator
  
  Wada Takashi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kanazawa University
Involvement of LPA1-MRTF-SRF in renal fibrosisPrincipal Investigator
- Principal Investigator
  
  SAKAI NORIHIKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa University
慢性腎臓病(CKD)および腎心相関にはたすエピジェネティクスをかいした新規機序Principal Investigator
- Principal Investigator
  
  坂井宣彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2009

All Journal Article Presentation Book Patent

[Book] 薬剤性腎障害診療Q&A2017
- Author(s)
  坂井宣彦、和田隆志
- Total Pages
  4
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26461218
[Journal Article] Intestinal Bacterial Translocation Contributes to Diabetic Kidney Disease2022
- Author(s)
  Linh HT, Iwata Y, Senda Y, Sakai-Takemori Y, Nakade Y, Oshima M, Nakagawa-Yoneda S, Ogura H, Sato K, Minami T, Kitajima S, Toyama T, Yamamura Y, Miyagawa T, Hara A, Shimizu M, Furuichi K, Sakai N, Yamada H, Asanuma K, Matsushima K, Wada T.
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: -
- DOI
  10.1681/asn.2021060843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-21K08224, KAKENHI-PROJECT-21K16188, KAKENHI-PROJECT-20KK0191
[Journal Article] Protective effect of <scp>d</scp>-alanine against acute kidney injury2022
- Author(s)
  Iwata Y, Nakade Y, Kitajima S, Yoneda-Nakagawa S, Oshima M, Sakai N, Ogura H, Sato K, Toyama T, Yamamura Y, Miyagawa T,Yamazaki H, Hara A, Shimizu M, Furuichi K, Mita M, Hamase K, Tanaka T, Nishida M, Muramatsu W, Yamamoto H, Shichino S, Ueha S, Matsushima K, Wada T.
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 322
- DOI
  10.1152/ajprenal.00198.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PLANNED-17H06394
[Journal Article] Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene2022
- Author(s)
  Takemori-Sakai Y, Satou K, Senda Y, Nakamura Y, Otani H, Maekawa A, Oe H, Oshima M, Yoneda-Nakagawa S, Miyagawa T, Sato K, Ogura H, Mori M, Wada T, Sakai Y, Yutani M, Matsumura T, Fujinaga Y, Gabata T, Wada T, Iwata Y.
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 28 Pages: 651-656
- DOI
  10.1016/j.jiac.2022.01.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-21K07021
[Journal Article] Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice2021
- Author(s)
  Makiishi Shohei、Furuichi Kengo、Yamamura Yuta、Sako Keisuke、Shinozaki Yasuyuki、Toyama Tadashi、Kitajima Shinji、Iwata Yasunori、Sakai Norihiko、Shimizu Miho、Hirose-Sugiura Tomoko、Kaneko Shuichi、Kato Yukio、Wada Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 9093-9093
- DOI
  10.1038/s41598-021-88724-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-20KK0191
[Journal Article] Impact of the relationship between hemoglobin levels and renal interstitial fibrosis on long-term outcomes in type 2 diabetes with biopsy-proven diabetic nephropathy2021
- Author(s)
  Shimizu Miho、Furuichi Kengo、Kitajima Shinji、Toyama Tadashi、Oshima Megumi、Ogura Hisayuki、Sato Koichi、Nakagawa Shiori、Yamamura Yuta、Miyagawa Taro、Hara Akinori、Iwata Yasunori、Sakai Norihiko、Kitagawa Kiyoki、Yoshimura Mitsuhiro、Yokoyama Hitoshi、Wada Takashi
- Journal Title
  
  BMC Nephrology
  
  Volume: 22 Pages: 319-319
- DOI
  10.1186/s12882-021-02510-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-20KK0191
[Journal Article] D-Serine inhibits the attachment and biofilm formation of methicillin-resistant Staphylococcus aureus.2021
- Author(s)
  Iwata Y, Sakai N, Yoneda I, Senda Y, Sakai-Takemori Y, Oshima M, Nakagawa-Yoneda S, Ogura H, Sato K, Minami T, Kitajima S, Toyama T, Yamamura Y, Miyagawa T, Hara A, Shimizu M, Furuichi K, Matsushima K, Wada T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 22 Pages: 50-56
- DOI
  10.1016/j.bbrc.2020.12.078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PLANNED-17H06394
[Journal Article] Two-year longitudinal trajectory patterns of albuminuria and subsequent rates of end-stage kidney disease and all-cause death: a nationwide cohort study of biopsy-proven diabetic kidney disease2021
- Author(s)
  Yamanouchi Masayuki、Iwata Yasunori、et al.
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 9
- DOI
  10.1136/bmjdrc-2021-002241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-20KK0191
[Journal Article] Combined changes in albuminuria and kidney function and subsequent risk for kidney failure in type 2 diabetes2021
- Author(s)
  Oshima Megumi、ToyaIwata Yasunori、et. al
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 9
- DOI
  10.1136/bmjdrc-2021-002311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-20K20309, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-20K11654, KAKENHI-PROJECT-20KK0191
[Journal Article] Serum hemoglobin concentration and risk of renal function decline in early stages of diabetic kidney disease: a nationwide, biopsy-based cohort study2021
- Author(s)
  Yamanouchi M,Furuichi K,Shimizu M,Toyama T,Yamamura Y,Oshima M,Kitajima S,Hara A,Iwata Y,Sakai N,Oba Y,Matsuoka S,Ikuma De,Mizuno H,Suwabe T,Hoshino J Sawa N,Yuzawa Y,Kitamura H,Suzuki Y,Sato H,Uesugi N,Ueda Y,Nishi S,Yokoyama H,Nishino T,Samejima K Kohagura K,Shibagaki Y,Makino H,Matsuo S,Ubara Y,Wada
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 37 Pages: 489-497
- DOI
  10.1093/ndt/gfab185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08715, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-20KK0191
[Journal Article] Relationship between autoantibodies to erythropoietin receptor and renal outcome in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis2020
- Author(s)
  Tran Trang Thi Thu、Hara Akinori、Kitagawa Kiyoki、Kitajima Shinji、Toyama Tadashi、Iwata Yasunori、Sakai Norihiko、Shimizu Miho、Kaneko Shuichi、Furuichi Kengo、Wada Takashi
- Journal Title
  
  Biomarkers
  
  Volume: 25 Pages: 194-200
- DOI
  10.1080/1354750x.2020.1727014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09691
[Journal Article] Propagermanium administration for patients with type 2 diabetes and nephropathy: A randomized pilot trial2020
- Author(s)
  Hara Akinori、Shimizu Miho、Hamaguchi Erika、Kakuda Hirokazu、Ikeda Kenzo、Okumura Toshiya、Kitagawa Kiyoki、Koshino Yoshitaka、Kobayashi Motoo、Takasawa Kazuya、Hisada Yukimasa、Toyama Tadashi、Iwata Yasunori、Sakai Norihiko、Wada Takashi
- Journal Title
  
  Endocrinology, Diabetes & Metabolism
  
  Volume: 3
- DOI
  10.1002/edm2.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03557
[Journal Article] Collagen Adhesion Gene Is Associated With Bloodstream Infections Caused by Methicillin-Resistant Staphylococcus Aureus2020
- Author(s)
  Iwata Y, Satou K, Furuichi K, Yoneda I, Matsumura T, et al.
- Journal Title
  
  International Journal of Infectious Diseases
  
  Volume: 91 Pages: 22-31
- DOI
  10.1016/j.ijid.2019.11.003
- NAID
  120006842044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07107, KAKENHI-PROJECT-18K08426, KAKENHI-PLANNED-17H06394, KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-17K09691, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392
[Journal Article] Clinicopathological features of fast eGFR decliners among patients with diabetic nephropathy2020
- Author(s)
  Furuichi Kengo、Shimizu Miho、Yamanouchi Masayuki、Hoshino Junichi、Sakai Norihiko、Iwata Yasunori、Toyama Tadashi、Kitajima Shinji、Hara Akinori、Wada Takashi　et.al.
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 8
- DOI
  10.1136/bmjdrc-2019-001157
- NAID
  120006892782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0191, KAKENHI-PROJECT-19H03557
[Journal Article] The Increased Frequency of Methicillin-Resistant Staphylococcus Aureus With Low MIC of Beta-Lactam Antibiotics Isolated From Hospitalized Patients2020
- Author(s)
  Iwata Y、Sakai N、Yoneda I、Satou K、Furuichi K、Senda Y、Sakai-Takemori Y、Wada T、Fujita S、Ogura H、Sato K、Minami T、Yamaguchi K、Kitajima S、Toyama T、Yamamura Y、Miyagawa T、Hara A、Shimizu M、Sakai Y、Ikeo K、Shichino S、Ueha S、Nakajima T、Matsushima K、Wada T
- Journal Title
  
  J Infect Chemother
  
  Volume: 26 Pages: 604-610
- DOI
  10.1016/j.jiac.2020.01.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06392, KAKENHI-PLANNED-17H06399, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394
[Journal Article] Relationship between anti-erythropoietin receptor autoantibodies and responsiveness to erythropoiesis-stimulating agents in patients on hemodialysis: a multi-center cross-sectional study.2020
- Author(s)
  Hara A, Koshino Y, Kurokawa Y, Shinozaki Y, Miyake T, Kitajima S, Toyama T, Iwata Y, Sakai N, Shimizu M, Furuichi K, Nakamura H, Wada T.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 24 Pages: 88-95
- DOI
  10.1007/s10157-019-01787-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03557
[Journal Article] Pathogenicity Characterization of Prevalent-Type Streptococcus dysgalactiae subsp. equisimilis Strains.2020
- Author(s)
  Matsue Miki、Ogura Kohei、Sugiyama Hironori、Miyoshi-Akiyama Tohru、Takemori-Sakai Yukiko、Iwata Yasunori、Wada Takashi、Okamoto Shigefumi
- Journal Title
  
  Front Microbiol.
  
  Volume: 11 Pages: 97-97
- DOI
  10.3389/fmicb.2020.00097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07133, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-17H04428, KAKENHI-ORGANIZER-17H06391
[Journal Article] Association of renal arteriosclerosis and hypertension with renal and cardiovascular outcomes in Japanese type 2 diabetes patients with diabetic nephropathy2019
- Author(s)
  Shimizu M, et al
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 印刷中 Pages: 1041-1049
- DOI
  10.1111/jdi.12981
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08979, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-19H03557
[Journal Article] The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage2019
- Author(s)
  Sakai Norihiko、Bain Gretchen、Furuichi Kengo、Iwata Yasunori、Nakamura Miki、Hara Akinori、Kitajima Shinji、Sagara Akihiro、Miyake Taito、Toyama Tadashi、Sato Koichi、Nakagawa Shiori、Shimizu Miho、Kaneko Shuichi、Wada Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 7414-7414
- DOI
  10.1038/s41598-019-43576-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09691
[Journal Article] Erythropoietin Signal Protected Human Umbilical Vein Endothelial Cells From High Glucose-Induced Injury2019
- Author(s)
  Yasuda Haruka、Iwata Yasunori、Nakajima Satoshi、Furuichi Kengo、Miyake Taito、Sakai Norihiko、Kitajima Shinji、Toyama Tadashi、Shinozaki Yasuyuki、Sagara Akihiro、Miyagawa Taro、Hara Akinori、Shimizu Miho、Kamikawa Yasutaka、Sato Kouichi、Oshima Megumi、Yoneda-Nakagawa Shiori、Kaneko Shuichi、Wada Takashi
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: in press Pages: 767-774
- DOI
  10.1111/nep.13518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09691, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-16K09608, KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19H03557
[Journal Article] Development of novel diagnostic system for pancreas cancer including early stages measuring mRNA of whole blood cells2019
- Author(s)
  Sakai Yoshio、Honda Masao、Matsui Shigeyuki、Komori Osamu、Murayama Toshinori、Fujiwara Tadami、Mizuno Masaaki、Imai Yasuhito、Yoshimura Kenichi、Nasti Alessandro、Wada Takashi、Iida Noriho、Kitahara Masaaki、Horii Rika、Toshikatsu Tamai、Nishikawa Masashi、Okafuji Hirofumi、Mizukoshi Eishiro、et al
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Pages: 1364-1388
- DOI
  10.1111/cas.13971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-15H01678, KAKENHI-PROJECT-16H02668, KAKENHI-PROJECT-18H03211, KAKENHI-PROJECT-16H06299, KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K09413, KAKENHI-PROJECT-17K15934
[Journal Article] Adipose tissue-derived stem cells prevent fibrosis in murine steatohepatitis by suppressing IL-17-mediated inflammation.2019
- Author(s)
  Yamato Masatoshi、Sakai Yoshio、Mochida Hatsune、Kawaguchi Kazunori、Takamura Masayuki、Usui Soichiro、Seki Akihiro、Mizukoshi Eishiro、Yamashita Taro、Yamashita Tatsuya、Ishida Kousuke、Nasti Alessandro、Tuyen Ho Thuy Bich、Komura Takuya、Yoshida Keiko、Wada Takashi、Honda Masao、Kaneko Shuichi
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Pages: 1432-1440
- DOI
  10.1111/jgh.14647
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-16K09425, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17K09413
[Journal Article] The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage.2019
- Author(s)
  Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, Kitajima S, Sagara A, Miyake T, Toyama T, Sato K, Nakagawa S, Shimizu M, Kaneko S, Wada T.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Pages: 7414-7414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03557
[Journal Article] Gut microbiota?derived D-serine protects against acute kidney injury2018
- Author(s)
  Yusuke Nakade, Yasunori Iwata, Takashi Wada, et al.
- Journal Title
  
  JCI Insight.
  
  Volume: 18;3(20) Pages: 97957-97957
- DOI
  10.1172/jci.insight.97957
- NAID
  120006733372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08978, KAKENHI-PROJECT-17K09691, KAKENHI-PROJECT-18K06117, KAKENHI-PROJECT-18K08426, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-17K18082
[Journal Article] Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood2018
- Author(s)
  Komura T, Yano M, Miyake A, Takabatake H, Miyazawa M, Ogawa N, Seki A, Honda M, Wada T, Matsui S, Kaneko S, Sakai Y.
- Journal Title
  
  Canadian Journal of Gastroenterology and Hepatology
  
  Volume: 7436205 Pages: 7436205-7436205
- DOI
  10.1155/2018/7436205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09413, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-18H02793
[Journal Article] Clinical and Pathological Significance of Autoantibodies to Erythropoietin Receptor in Type 2 Diabetic Patients With CKD.2018
- Author(s)
  Hara A, Furuichi K, Koshino A, Yasuda H, Tran T, Iwata Y, Sakai N, Shimizu M, Kaneko S, Nakamura H, Wada T.
- Journal Title
  
  Kidney International Reports
  
  Volume: 3 Pages: 133-141
- DOI
  10.1016/j.ekir.2017.08.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09608, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-17K09691
[Journal Article] Evaluation of renal oxygen saturation using photoacoustic imaging for the early prediction of chronic renal function in a model of ischemia-induced acute kidney injury.2018
- Author(s)
  Okumura Kenichiro、Matsumoto Junichi、Iwata Yasunori、Yoshida Kotaro、Yoneda Norihide、Ogi Takahiro、Kitao Azusa、Kozaka Kazuto、Koda Wataru、Kobayashi Satoshi、Inoue Dai、Sakai Norihiko、Furuichi Kengo、Wada Takashi、Gabata Toshifumi
- Journal Title
  
  PLoS One.
  
  Volume: 13
- DOI
  10.1371/journal.pone.0206461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09691, KAKENHI-PROJECT-18K07669, KAKENHI-PROJECT-16K10343, KAKENHI-PROJECT-16K19811, KAKENHI-PROJECT-16K19813
[Journal Article] Involvement of p38MAPK in Impaired Neutrophil Bactericidal Activity of Hemodialysis Patients.2018
- Author(s)
  Kamikawa Yasutaka、Sakai Norihiko、Miyake Taito、Sagara Akihiro、Shinozaki Yasuyuki、Kitajima Shinji、Toyama Tadashi、Hara Akinori、Iwata Yasunori、Shimizu Miho、Furuichi Kengo、Imamura Ryu、Suda Takashi、Kaneko Shuichi、Wada Takashi
- Journal Title
  
  Therapeutic Apheresis and Dialysis
  
  Volume: - Pages: 345-354
- DOI
  10.1111/1744-9987.12651
- NAID
  120006498382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06394, KAKENHI-PLANNED-26110002, KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-17K09691
[Journal Article] Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease.2017
- Author(s)
  Shinozaki Yasuyuki、Furuichi Kengo、Toyama Tadashi、Kitajima Shinji、Hara Akinori、Iwata Yasunori、Sakai Norihiko、Shimizu Miho、Kaneko Shuichi、Isozumi Noriyoshi、Nagamori Shushi、Kanai Yoshikatsu、Sugiura Tomoko、Kato Yukio、Wada Takashi
- Journal Title
  
  Kidney Int.
  
  Volume: 92 Pages: 1356-1369
- DOI
  10.1016/j.kint.2017.04.032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-15H04664, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-17H04190, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-16K15326
[Journal Article] Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus2017
- Author(s)
  Iwata Y.、Satou K.、Tsuzuku H.、Furuichi K.、Senda Y.、Sakai-Takemori Y.、Wada T.、Fujita S.、Miyake T.、Yasuda H.、Sakai N.、Kitajima S.、Toyama T.、Shinozaki Y.、Sagara A.、Miyagawa T.、Hara A.、Shimizu M.、Kamikawa Y.、Kaneko S.、Wada T.
- Journal Title
  
  Eur J Clin Microbiol Infect Dis.
  
  Volume: 36 Pages: 1839-1845
- DOI
  10.1007/s10096-017-2999-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06394
[Journal Article] Lysophosphatidic acid signaling through its receptor initiates pro-fibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor2017
- Author(s)
  Sakai N, Chun J, Duffield JS, Lagares D, Wada T, Luster AD, Tager AM.
- Journal Title
  
  Kidney International
  
  Volume: 91 Pages: 628-641
- DOI
  10.1016/j.kint.2016.09.030
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293127, KAKENHI-PROJECT-26461218
[Journal Article] Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis.2017
- Author(s)
  Sakai Norihiko、Nakamura Miki、Lipson Kenneth E.、Miyake Taito、Kamikawa Yasutaka、Sagara Akihiro、Shinozaki Yasuyuki、Kitajima Shinji、Toyama Tadashi、Hara Akinori、Iwata Yasunori、Shimizu Miho、Furuichi Kengo、Kaneko Shuichi、Tager Andrew M.、Wada Takashi
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 5392-5392
- DOI
  10.1038/s41598-017-05624-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09691, KAKENHI-PLANNED-17H06394, KAKENHI-PROJECT-15K09251
[Journal Article] Inhibition of NLRP3 inflammasome as a therapeutic intervention in crystal-induced nephropathy2016
- Author(s)
  Sakai N, Furuichi K, Wada T.
- Journal Title
  
  Kidney International
  
  Volume: 90 Pages: 466-468
- DOI
  10.1016/j.kint.2016.05.003
- NAID
  120005899106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293127, KAKENHI-PROJECT-26461218
[Journal Article] 免疫抑制薬による腎障害2016
- Author(s)
  坂井宣彦、和田隆志
- Journal Title
  
  日本腎臓学会雑誌
  
  Volume: 58 Pages: 1073-1078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461218
[Journal Article] Revisiting inflammation in diabetic nephropathy: the role of the Nlrp3 inflammasome in glomerular resident cells.2015
- Author(s)
  Sakai N, Wada T
- Journal Title
  
  Kidney Int
  
  Volume: 87 Pages: 12-14
- DOI
  10.1038/ki.2014.322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670269, KAKENHI-PROJECT-26461218, KAKENHI-PROJECT-26293127
[Journal Article] Relationship between Serum Uric Acid Levels and Chronic Kidney Disease in a Japanese Cohort with Normal or Mildly Reduced Kidney Function.a2015
- Author(s)
  Toyama T, Furuichi K, Shimizu M, Hara A, Iwata Y, Sakai N, Perkovic V, Kobayashi M, Mano T, Kaneko S, Wada T.
- Journal Title
  
  PLOS ONE
  
  Volume: 10
- DOI
  10.1371/journal.pone.0137449
- NAID
  120005680030
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-26461218, KAKENHI-PROJECT-26870218, KAKENHI-PROJECT-26253046
[Journal Article] Association of PAX2 and Other Gene Mutations with the Clinical Manifestations of Renal Coloboma Syndrome.2015
- Author(s)
  Okumura T, Furuichi K, Higashide T, Sakurai M, Hashimoto S, Shinozaki Y, Hara A, Iwata Y, Sakai N, Sugiyama K, Kaneko S, Wada T.
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0142843
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09251, KAKENHI-PROJECT-26461218, KAKENHI-PROJECT-15K15328, KAKENHI-PROJECT-26293126
[Journal Article] Risk factors associated with relapse or infectious complications in Japanese patients with microscopic polyangiitis.2015
- Author(s)
  Kitagawa K, Furuichi K, Sagara A, Shinozaki Y, Kitajima S, Toyama T, Hara A, Iwata Y, Sakai N, Shimizu M, Kaneko S, Wada T
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461218
[Journal Article] T Helper 2 Cytokine Signaling in Bone Marrow-Derived Fibroblasts: A Target for Renal Fibrosis.2015
- Author(s)
  Sakai N, Wada T
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 26 Pages: 2896-2898
- DOI
  10.1681/asn.2015040469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461218
[Journal Article] 血栓性微小血管症（thrombotic microangiopathy）における血漿交換の意義2014
- Author(s)
  坂井宣彦，和田隆志
- Journal Title
  
  日本腎臓学会雑誌
  
  Volume: 56 Pages: 1082-1089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461218
[Patent] 腎障害の予防又は治療用の医薬組成物2018
- Inventor(s)
  和田隆志、古市賢吾、坂井宣彦ら
- Industrial Property Rights Holder
  和田隆志、古市賢吾、坂井宣彦ら
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] The involvement of cytoskeleton-dependent signaling pathway mediated by bioactive substances in the pathogenesis of organ fibrosis.2019
- Author(s)
  Norihiko Sakai, Takashi Wada
- Organizer
  The 62nd Annual Meeting of the Japanese Society of Nephrology
- Invited
- Data Source
  KAKENHI-PLANNED-17H06394
[Presentation] The involvement of cytoskeleton-dependent signaling pathway mediated by biological substances in the pathogenesis of organ fibrosis2019
- Author(s)
  Norihiko Sakai, Takashi Wada
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] Regulation of renal fibroblast function by MRTF-focal adhesion in response to TGF-b12019
- Author(s)
  Norihiko Sakai, Koichi Sato, Hisayuki Ogura, Taro Miyagawa, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Takashi Wada
- Organizer
  アメリカ腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] The involvement of cytoskeleton-dependent signaling pathway mediated by bioactive substances in the pathogenesis of organ fibrosis.2019
- Author(s)
  坂井宣彦・和田隆志
- Organizer
  第62回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06394
[Presentation] がん治療による薬剤性腎障害－２つのガイドラインをふまえて－2019
- Author(s)
  坂井宣彦、和田隆志
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] ANCA関連血管炎における抗エリスロポエチン受容体抗体の臨床的意義2018
- Author(s)
  原章規・北川清樹・北島信治・遠山直志・岩田恭宜・坂井宣彦・清水美保・古市賢吾・和田隆志
- Organizer
  第62回日本リウマチ学会総会・学術総会
- Data Source
  KAKENHI-PLANNED-17H06394
[Presentation] Regulation of renal fibroblast migration, proliferation and myofibroblast differentiation by LPA-LPA1 signaling via specific G proteins2018
- Author(s)
  Norihiko Sakai, Koichi Sato, Taito Miyake, Akihiro Sagara, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Takashi Wada.
- Organizer
  米国腎臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] リゾフォスファチジン酸シグナルの腹膜中皮細胞遊走能および筋線維芽細胞分化にはたす意義2018
- Author(s)
  坂井宣彦・佐藤晃一・三宅泰人・北島信治・遠山直志・原章規・岩田恭宜・清水美保・古市賢吾・和田隆志
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] マウス腹膜線維化モデルにおけるトレハロースの線維化抑制効果の検討2017
- Author(s)
  三宅泰人・坂井宣彦・古市賢吾・和田隆志
- Organizer
  第23回日本腹膜透析学会学術集会・総会
- Data Source
  KAKENHI-PLANNED-17H06394
[Presentation] マウス腎線維化モデルにおけるリゾフォスファチジン酸シグナルの意義2017
- Author(s)
  坂井宣彦，上川康貴，三宅泰人，相良明宏，北島信治，遠山忠志原章規，岩田恭宜，清水美保，古市賢吾，和田隆志
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] Peritoneal mesothelial cell migration and myofibroblast differentiation are dependent on LPA-LPA12017
- Author(s)
  Norihiko Sakai, Taito Miyake, Koichi Sato, Akihiro Sagara, Shinji Kitajima, Tadashi Toyama, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Takashi Wada
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] コレステロール塞栓症の病態からみたLDLアフェレシス療法の可能性2017
- Author(s)
  坂井宣彦、古市賢吾、和田隆志
- Organizer
  日本アフェレシス学会総会
- Data Source
  KAKENHI-PROJECT-17K09691
[Presentation] 臓器線維化進展機序における生理活性脂質の意義2016
- Author(s)
  坂井宣彦、和田隆志
- Organizer
  日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] 腹膜中皮細胞の遊走能および筋線維芽細胞分化にはたすlysophosphatidic acid (LPA)-LPA1の意義2015
- Author(s)
  坂井宣彦、和田隆志
- Organizer
  日本透析医学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] LPA-LPA1 signaling regulates fibroblast proliferation and myofibroblast differentiation dependent on epithelial cell-fibroblast interaction.2015
- Author(s)
  Norihiko Sakai, Taito Miyake, Yasutaka Kamikawa, Akihiro Sagara, Yasuyuki Shinozaki, Shinji Kitajima, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Takashi Wada
- Organizer
  米国腎臓学会
- Place of Presentation
  サンディエゴ（米国）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] 臓器線維化機序におけるリゾフォスファチジン酸の意義2015
- Author(s)
  坂井宣彦、和田隆志
- Organizer
  日本臨床分子形態学会
- Place of Presentation
  長崎大学（長崎県長崎市）
- Year and Date
  2015-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] マウス腎線維化モデルにおけるlysophosphatidic acid (LPA)-LPA1の意義2014
- Author(s)
  坂井宣彦，Andrew M. tager，和田隆志
- Organizer
  日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-07-06
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] LPA-LPA1 signaling directs peritoneal mesothelial cell migration and myofibroblast differentiation in the pathogenesis of peritoneal fibrosis2014
- Author(s)
  Norihiko Sakai, Takashi Wada, Andrew M. Tager
- Organizer
  米国腎臓学会総会
- Place of Presentation
  フィラデルフィアコンベンションセンター（フィラデルフィア）
- Year and Date
  2014-11-13
- Data Source
  KAKENHI-PROJECT-26461218
[Presentation] 腎間質線維化機序におけるfibrocyteを介したエピジェネティクスの意義2009
- Author(s)
  坂井宣彦
- Organizer
  第15回分子腎臓研究会
- Place of Presentation
  メルパルク京都(京都市)
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790802

1. WADA TAKASHI (40334784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
2. 古市賢吾 (50432125)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
3. 岩田恭宜 (90432137)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
4. Tager Andrew M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. Sakai Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NAGAMORI Shushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. HARA Akinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
8. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. KOMORI Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. ITO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. MURAYAMA Toshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MATSUMURA Takuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. GABATA Toshifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. OGURA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. OGURA Kohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SATOH Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. YUZAWA Yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 遠山直志

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
19. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 加藤将夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 金井好克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 金子一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 清水美保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 松島綱治

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
25. 大島恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
26. 中出祐介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 片根真澄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 宮本哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 酒井佳夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
31. 七野成之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 松井秀俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 松井茂之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 高村雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 山下竜也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 池尾一穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 小林聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 香田渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 吉田耕太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 井上大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 奥村健一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 須田貴司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 岡本成史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 中村裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sakai norihiko 坂井 宣彦

SAKAI NORIHIKO 坂井 宣彦

坂井 宣彦 サカイ ノリヒコ

Research Projects

Research Products

Co-Researchers

線維化組織微小環境の制御による慢性腎臓病進展機序の解明と臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

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キラルアミノ酸による糖尿病性腎症の病態解明と新規バイオマーカー開発

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Involvement of cytoskeleton-dependent signaling in renal fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Inflammation and related molecular preventive medicine in kidney diseases

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Involvement of LPA1-MRTF-SRF in renal fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性腎臓病(CKD)および腎心相関にはたすエピジェネティクスをかいした新規機序Principal Investigator

Principal Investigator

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Research Institution

[Book] 薬剤性腎障害診療Q&A2017

Author(s)

Total Pages

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Data Source

[Journal Article] Intestinal Bacterial Translocation Contributes to Diabetic Kidney Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective effect of <scp>d</scp>-alanine against acute kidney injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of the relationship between hemoglobin levels and renal interstitial fibrosis on long-term outcomes in type 2 diabetes with biopsy-proven diabetic nephropathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] D-Serine inhibits the attachment and biofilm formation of methicillin-resistant Staphylococcus aureus.2021

Author(s)

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DOI

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[Journal Article] Two-year longitudinal trajectory patterns of albuminuria and subsequent rates of end-stage kidney disease and all-cause death: a nationwide cohort study of biopsy-proven diabetic kidney disease2021

Author(s)

Journal Title

sakai norihiko 坂井宣彦

SAKAI NORIHIKO 坂井宣彦

坂井宣彦サカイノリヒコ