Osanai Makoto 小山内誠

… Alternative Names

小山内誠オサナイマコト

OSANAI Makoto 小山内誠

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Researcher Number	60381266
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 札幌医科大学, 医学部, 教授 2018 – 2019: 札幌医科大学, 医学部, 教授 2017: 札幌医科大学, 医学部, 准教授 2013: 高知大学, 教育研究部・医療学系, 准教授 2011 – 2013: 高知大学, 医歯学系, 准教授 … More 2009 – 2010: Kochi University, 教育研究部・医療学系, 准教授 2008: Kochi University, 教育研究部医療学系, 准教授 2006: Sapporo Medical University, School of Medicine, Assistant Professor, 医学部, 講師 2005: 札幌医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Basic Section 49020:Human pathology-related / Human pathology Except Principal Investigator Basic Section 49020:Human pathology-related / Human pathology / Cancer epidemiology and prevention
Keywords	Principal Investigator レチノイン酸 / ビタミンA / 糖尿病腎症 / 糖尿病 / 腎メサンギウム細胞 / 星細胞 / レチノイン酸代謝酵素CYP26 / HNF-4α / claudin / アポトーシス … More / 腎 / 実験病理学 / 腎不全 / 糖尿病性腎症 / Ca absorption / diabetic retinopathv / glial cell / retinoic acid / tight junction / human nasal mucosa / 上皮細胞極性 / フェンス機能 / シグナル伝達 / occludin / クローディン / オクルジン / Toll-like receptor / TSLP / 鼻アレルギー / Ca吸収 / 糖尿病網膜症 / グリア細胞 / タイト結合 / ヒト鼻粘膜 / CYP26A1 / 癌 / 癌遺伝子 / 発癌 / 腫瘍 … More Except Principal Investigator oncostatin M / claudin-2 / トランスクリプトーム / 舌癌 / 膵癌 / がん悪性化 / ビタミンA / CYP26A1 / 口腔がん / 膵がん / レチノイン酸 / bile canaliculi formation / hepatic cell polarity / tight junction / hepatocyte / cholestasis / 毛細胆管形成 / 肝細胞極性 / タイト結合 / 肝細胞 / 黄疸 / RAR / PPARG / VDR / フコキサンチノール / ビタミンＤ / がん幹細胞標的分子 / 薬物代謝酵素 / がん遺伝子 / 分子イメージング / カロテノイド / ビタミンD / 分子標的治療 / がん化学予防 / 核内受容体 / 大腸がん幹細胞 Less

レチノイン酸欠乏状態の腎メサンギウム細胞を起点に理解する新しい糖尿病性腎症の病理Principal Investigator
- Principal Investigator
  
  小山内誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University
レチノイン酸特異的代謝酵素CYP26のレチノイン酸非依存性がん悪性化機構の解明
- Principal Investigator
  
  小野佑輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University
Retinoic acid-deficient renal mesangial cells are responsible for the development of diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  Osanai Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University
Nuclear receptors as molecular regulator and chemopreventive targets of colon cancer stem cells.
- Principal Investigator
  
  MASUDA Sonoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cancer epidemiology and prevention
- Research Institution
  Health Sciences University of Hokkaido
Retinoic acid metabolizing enzyme CYP26A1 is a candidate oncogene, and a possible therapeutic target for cancers.Principal Investigator
- Principal Investigator
  
  OSANAI Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kochi University
Biological barrier and human diseasesPrincipal Investigator
- Principal Investigator
  
  KOJIMA Takashi, 小山内誠
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Sapporo Medical University
Regulation of bile canalicular barrier by a novel tight junction protein claudin-2 during cholestasis
- Principal Investigator
  
  KOJIMA Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University

[Book] The tight junction, intercellular seal as a cell-signaling player - Protocols for examination for its status.(Turksen K (Ed.))2010
- Author(s)
  Osanai M. Springer.
- Publisher
  Claudins : Methods and Protocols (Methods in Molecular Biology).
- Data Source
  KAKENHI-PROJECT-20590402
[Book] Tight junctions.(Schwab M (Ed.))2009
- Author(s)
  Osanai M. Springer.
- Publisher
  Encyclopedia of Cancer, Second edition.
- Data Source
  KAKENHI-PROJECT-20590402
[Book] Encyclopedia of Cancer2007
- Author(s)
  Osanai M
- Publisher
  Springer (in press)
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas2024
- Author(s)
  Aoki Hironori、Takasawa Akira、Yamamoto Eiichiro、Niinuma Takeshi、Yamano Hiro-o、Harada Taku、Kubo Toshiyuki、Yorozu Akira、Kitajima Hiroshi、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Shinohara Toshiya、Nakase Hiroshi、Sugai Tamotsu、Osanai Makoto、Suzuki Hiromu
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 24 Issue: 1 Pages: 24-24
- DOI
  10.1186/s12876-024-03175-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420, KAKENHI-PROJECT-23K24186
[Journal Article] Invasive pulmonary aspergillosis with candidiasis: usefulness of molecular and ultrastructural morphological analysis on FFPE tissue for invasive fungal infections2023
- Author(s)
  Kubota Yusaku、Takasawa Akira、Ono Yusuke、Aoyama Tomoyuki、Takasawa Kumi、Tada Akinori、Magara Kazufumi、Murakami Taro、Daimon Fuminori、Yamamoto Soh、Sato Shota、Hiratsuka Yutaro、Kyuno Daisuke、Osanai Makoto
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 56 Issue: 2 Pages: 144-151
- DOI
  10.1007/s00795-023-00349-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-22K06944, KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series2023
- Author(s)
  Daisuke Kyuno 1 , Masatoshi Tateno 2 , Yusuke Ono 1 , Kazufumi Magara 1 , Kumi Takasawa 1 , Akira Takasawa 1 , Makoto Osanai 1
- Journal Title
  
  Heliyon .
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983
[Journal Article] Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers.2023
- Author(s)
  Yoshido A, Sudo G, Takasawa A, Aoki H, Kitajima H, Yamamoto E, Niinuma T, Harada T, Kubo T, Sasaki H, Ishiguro K, Yorozu A, Kai M, Katanuma A, Yamano HO, Osanai M, Nakase H, Suzuki H.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 38 Issue: 2 Pages: 301-310
- DOI
  10.1111/jgh.16055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-21K15556, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420
[Journal Article] A novel approach to diagnosing crystal-storing histiocytosis: utility of scanning electron microscopy for formalin-fixed paraffin-embedded tissue specimens2023
- Author(s)
  Kazufumi Magara 1 , Akira Takasawa 2 , Keisuke Kikuchi 3 , Taro Sugawara 4 , Taro Murakami 1 , Daisuke Kyuno 1 , Yusuke Ono 1 , Kumi Takasawa 1 , Yasunao Numata 5 , Shigeru Sasaki 5 , Hiroshi Nakase 5 , Tadashi Hasegawa 4 , Makoto Osanai 1
- Journal Title
  
  Med Mol Morphol .
  
  Volume: 56 Issue: 4 Pages: 297-302
- DOI
  10.1007/s00795-023-00363-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] Retinoic acid metabolism in cancer: potential feasibility of retinoic acid metabolism blocking therapy2023
- Author(s)
  Osanai Makoto、Takasawa Akira、Takasawa Kumi、Kyuno Daisuke、Ono Yusuke、Magara Kazufumi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 56 Issue: 1 Pages: 1-10
- DOI
  10.1007/s00795-022-00345-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K06445
[Journal Article] TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells2023
- Author(s)
  Kitajima Hiroshi、Maruyama Reo、Niinuma Takeshi、Yamamoto Eiichiro、Takasawa Akira、Takasawa Kumi、Ishiguro Kazuya、Tsuyada Akihiro、Suzuki Ryo、Sudo Gota、Kubo Toshiyuki、Idogawa Masashi、Toyota Mutsumi、Yoshido Ayano、Kumegawa Kohei、Kai Masahiro、Tokino Takashi、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 7 Pages: 424-424
- DOI
  10.1038/s41419-023-05953-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07173, KAKENHI-PROJECT-23K06426, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24186
[Journal Article] ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma2023
- Author(s)
  Sekiguchi Shohei、Yorozu Akira、Okazaki Fumika、Niinuma Takeshi、Takasawa Akira、Yamamoto Eiichiro、Kitajima Hiroshi、Kubo Toshiyuki、Hatanaka Yui、Nishiyama Koyo、Ogi Kazuhiro、Kai Masahiro、Hirohashi Yoshihiko、Torigoe Toshihiko、Kojima Takashi、Osanai Makoto、Takano Kenichi、Miyazaki Akihiro、Suzuki Hiromu
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 17 Pages: 4303-4303
- DOI
  10.3390/cancers15174303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-23K24186
[Journal Article] Emerging roles of transmembrane‐type tight junction proteins in cancers2023
- Author(s)
  Takasawa Akira、Takasawa Kumi、Murata Masaki、Osanai Makoto、Sawada Norimasa
- Journal Title
  
  Pathology International
  
  Volume: 73 Issue: 8 Pages: 331-340
- DOI
  10.1111/pin.13349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06426, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-21K06890
[Journal Article] CXCL12 is expressed by skeletal muscle cells in tongue oral squamous cell carcinoma.2023
- Author(s)
  Yorozu A, Sekiguchi S, Takasawa A, Okazaki F, Niinuma T, Kitajima H, Yamamoto E, Kai M, Toyota M, Hatanaka Y, Nishiyama K, Ogi K, Dehari H, Obata K, Kurose M, Kondo A, Osanai M, Miyazaki A, Takano K, Suzuki H.
- Journal Title
  
  Cancer Med.
  
  Volume: 12 Issue: 5 Pages: 5953-5963
- DOI
  10.1002/cam4.5392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445
[Journal Article] Vitamin D metabolism in cancer: potential feasibility of vitamin D metabolism blocking therapy2023
- Author(s)
  Kamiya Sakura、Nakamori Yuna、Takasawa Akira、Takasawa Kumi、Kyuno Daisuke、Ono Yusuke、Magara Kazufumi、Osanai Makoto
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 7 Issue: 2 Pages: 85-93
- DOI
  10.1007/s00795-023-00348-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K06445
[Journal Article] Establishment and characterization of a novel dedifferentiated chondrosarcoma cell line, SMU-DDCS, harboring an IDH1 mutation2023
- Author(s)
  Emori Makoto、Nakahashi Naoya、Takasawa Akira、Murata Kenji、Murahashi Yasutaka、Shimizu Junya、Tsukahara Tomohide、Sugita Shintaro、Takada Kohichi、Hasegawa Tadashi、Osanai Makoto、Iba Kosuke
- Journal Title
  
  Human Cell
  
  Volume: 36 Issue: 6 Pages: 2195-2203
- DOI
  10.1007/s13577-023-00944-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-23K06445
[Journal Article] Suppression of the vitamin D metabolizing enzyme CYP24A1 provides increased sensitivity to chemotherapeutic drugs in breast cancer2023
- Author(s)
  Kamiya Sakura、Nakamori Yuna、Takasawa Akira、Takasawa Kumi、Kyuno Daisuke、Ono Yusuke、Magara Kazufumi、Osanai Makoto
- Journal Title
  
  Oncology Reports
  
  Volume: 49 Issue: 5 Pages: 85-85
- DOI
  10.3892/or.2023.8522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K06445
[Journal Article] Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series2023
- Author(s)
  Kyuno Daisuke, Tateno Masatoshi, Ono Yusuke, Magara Kazufumi, Takasawa Kumi, Takasawa Akira, Osanai Makoto
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 10 Pages: e20564-e20564
- DOI
  10.1016/j.heliyon.2023.e20564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06445
[Journal Article] Elevated expression of endocan in the development of cervical squamous neoplasia of the uterus2023
- Author(s)
  Sato M, Inoue A, Takasawa A, Takasawa K, Kyuno D, Ono Y, Magara K, Osanai M.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 56 Issue: 3 Pages: 187-193
- DOI
  10.1007/s00795-023-00353-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] COVID-19-associated disseminated mucormycosis: An autopsy case report2022
- Author(s)
  Kyuno Daisuke、Kubo Terufumi、Tsujiwaki Mitsuhiro、Sugita Shintaro、Hosaka Michiko、Ito Hazuki、Harada Keisuke、Takasawa Akira、Kubota Yusaku、Takasawa Kumi、Ono Yusuke、Magara Kazufumi、Narimatsu Eichi、Hasegawa Tadashi、Osanai Makoto
- Journal Title
  
  World Journal of Clinical Cases
  
  Volume: 10 Issue: 28 Pages: 10358-10365
- DOI
  10.12998/wjcc.v10.i28.10358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409
[Journal Article] Claudin-18.2 as a therapeutic target in cancers: cumulative findings from basic research and clinical trials2021
- Author(s)
  Kyuno Daisuke、Takasawa Akira、Takasawa Kumi、Ono Yusuke、Aoyama Tomoyuki、Magara Kazufumi、Nakamori Yuna、Takemasa Ichiro、Osanai Makoto
- Journal Title
  
  Tissue Barriers
  
  Volume: 10 Issue: 1 Pages: 1967080-1967080
- DOI
  10.1080/21688370.2021.1967080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-21K08715, KAKENHI-PROJECT-20K16196, KAKENHI-PROJECT-22K06983
[Journal Article] Identification of Coiled-Coil Domain-Containing Protein 180 and Leucine-Rich Repeat-Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue.2019
- Author(s)
  Aoyama T, Takasawa A, Takasawa K, Ono Y, Emori M, Murata M, Hayasaka T, Fujitani N, Osanai M, Yamashita T, Hasegawa T, Sawada N.
- Journal Title
  
  Am J Pathol.
  
  Volume: in press Issue: 5 Pages: 1015-1028
- DOI
  10.1016/j.ajpath.2019.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-19K16588, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K10974
[Journal Article] Elevated expression of G protein-coupled receptor 30 (GPR30) is associated with poor prognosis in patients with uterine cervical adenocarcinoma2019
- Author(s)
  Ino Y, Akimoto T, Takasawa A, Takasawa K, Aoyama T, Ueda A, Ota M, Magara K, Tagami Y, Murata M, Hasegawa T, Saito T, Sawada N, Osanai M
- Journal Title
  
  Histol Histopathol
  
  Volume: 18157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08697
[Journal Article] Immunoreactivity patterns of tight junction proteins are useful for differential diagnosis of human salivary gland tumors.2019
- Author(s)
  Aoyama T, Takasawa A, Murata M, Osanai M, Takano K, Hasagawa T, Sawada N.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 52 Issue: 1 Pages: 23-35
- DOI
  10.1007/s00795-018-0199-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698
[Journal Article] Retinoic acid-metabolizing enzyme CYP26A1 promotes skin carcinogenesis induced by DMBA2018
- Author(s)
  Osanai M, Takasawa A, Takasawa K, Murata M, Sawada N
- Journal Title
  
  Oncol Letter
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08697
[Journal Article] Cytotoxicity of Clostridium perfringens enterotoxin depends on the conditions of claudin-4 in ovarian carcinoma cells2018
- Author(s)
  Tanaka S, Aoyama T, Ogawa M, Takasawa A, Murata M, Osanai M, Saito T, Sawada N
- Journal Title
  
  Exp Cell Res
  
  Volume: 371 Issue: 1 Pages: 278-286
- DOI
  10.1016/j.yexcr.2018.08.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-17K08735, KAKENHI-PROJECT-16K08693
[Journal Article] Retinoic acid-metabolizing enzyme CYP26A1 promotes skin carcinogenesis induced by DMBA2018
- Author(s)
  Osanai M, Takasawa A, Takasawa K, Murata M, Sawada N
- Journal Title
  
  Oncol Lett
  
  Volume: 15 Pages: 9987-9993
- DOI
  10.3892/ol.2018.8599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693
[Journal Article] Estrogen/GPR30 signaling contributes to the malignant potentials of ER-negative cervical adenocarcinoma via regulation of claudin-1 expression2018
- Author(s)
  Akimoto T, Takasawa A, Takasawa K, Aoyama T, Murata M, Osanai M, Saito T, Sawada N
- Journal Title
  
  Neoplasia
  
  Volume: 10 Issue: 10 Pages: 1083-1093
- DOI
  10.1016/j.neo.2018.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693
[Journal Article] Cellular retinoic acid bioavailability in various pathologies and its therapeutic implication2017
- Author(s)
  Osanai M
- Journal Title
  
  Pathol Int
  
  Volume: 67 Issue: 6 Pages: 281-291
- DOI
  10.1111/pin.12532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08697
[Journal Article] Prognostic significance of the co-expression of EGFR and HER2 in adenocarcinoma of the uterine cervix2017
- Author(s)
  Ueda A. Takasawa A. Akimoto T, Takasawa K, Aoyama T, Ino Y, Nojima N, Ono Y, Murata M, Osanai M, Hasegawa T, Sawana N
- Journal Title
  
  PLoS ONE
  
  Volume: 12 Issue: 8 Pages: e0184123-e0184123
- DOI
  10.1371/journal.pone.0184123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698
[Journal Article] Claudin-18 coupled with EGFR/ERK signaling contributes to the malignant potentials of bile duct cancer.2017
- Author(s)
  Takasawa K, Takasawa A, Osanai M, Aoyama T, Ono Y, Kono T, Hirohashi Y, Murata M, Sawada N.
- Journal Title
  
  Cancer Lett.
  
  Volume: 403 Pages: 66-73
- DOI
  10.1016/j.canlet.2017.05.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-16K21250
[Journal Article] Prognostic significance of the co-expression of EGFR and HER2 in adenocarcinoma of the uterine cervix.2017
- Author(s)
  Ueda A, Takasawa A, Akimoto T, Takasawa K, Aoyama T, Ino Y, Nojima M, Ono Y, Murata M, Osanai M, Hasegawa T, Saito T, Sawada N.
- Journal Title
  
  PLoS One
  
  Volume: 12(8) Issue: 2 Pages: 172-180
- DOI
  10.1016/j.yexcr.2018.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-16K21250, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084
[Journal Article] Elevated expression of JAM-A promotes neoplastic properties of lung adenocarcinoma.2017
- Author(s)
  Magara K, Takasawa A, Osanai M, Ota M, Tagami Y, Ono Y, Takasawa K, Murata M, Hirohashi Y, Miyajima M, Yamada G, Hasegawa T, Sawada N.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108(11) Issue: 11 Pages: 2306-2314
- DOI
  10.1111/cas.13385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698
[Journal Article] Claudins in cancer: bench to bedside2016
- Author(s)
  Makoto Osanai, Akira Takasawa, Masaki Murata, Norimasa Sawada
- Journal Title
  
  Pflugers Archiv
  
  Volume: - Issue: 1 Pages: 55-67
- DOI
  10.1007/s00424-016-1877-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460421, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K08698
[Journal Article] The error-prone DNA polymerase ι provides quantitative resistance to lung tumorigenesis and mutagenesis in mice2013
- Author(s)
  Iguchi M, Osanai M, Hayashi Y, Koentgen F, Lee GH
- Journal Title
  
  Oncogene advance online publication
  
  Volume: 33 Issue: 27 Pages: 3612-3617
- DOI
  10.1038/onc.2013.331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501324, KAKENHI-PROJECT-26460473
[Journal Article] Emerging novel treatment strategies for diabetic eye diseases.2010
- Author(s)
  Osanai M, Lee GH, Sawada N
- Journal Title
  
  Current Diabetic Reviews
  
  Volume: 6 Pages: 35-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Emerging novel treatment strategies for diabetic eye diseases.2010
- Author(s)
  Osanai M, Lee GH, Sawada N.
- Journal Title
  
  Current Diabetic Reviews 6
  
  Pages: 35-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Insulin-independent promotion of chemically induced hapatocellular tumor development in genetically diebetic mice.2010
- Author(s)
  Yamasaki K, Hayashi Y, Okamoto S, Osanai M, Lee GH.
- Journal Title
  
  Cancer Sci 101
  
  Pages: 65-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Insulin-independent promotion of chemically induced hapatocellular tumor development in genetically diebetic mice.2010
- Author(s)
  Yamasaki K, Hayashi Y, Okamoto S, Osanai M, Lee GH
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 65-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Oncogenic and cell survival properties of the retinoic acid metabolizing enzyme, CYP26A1.2010
- Author(s)
  Osanai M, Sawada N, Lee GH
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 1135-1144
- NAID
  120002187918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Oncogenic and cell survival properties of the retinoic acid metabolizing enzyme2010
- Author(s)
  Osanai M, Sawada N, Lee GH.
- Journal Title
  
  CYP26A1. Oncogene 29
  
  Pages: 1135-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] The tight junction, intercellular seal as a cell-signaling player-Protocols for examination for its status2009
- Author(s)
  Osanai M
- Journal Title
  
  Methods in Molecular Biology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca^<2+> absorption between enterocytes.2008
- Author(s)
  Fujita H, Sugimoto K, InatomiS, Maeda T, Osanai M, Uchiyama Y, Yamamoto Y, Sawada N, Chiba H.
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 1912-1921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation.2008
- Author(s)
  Koizumi J, Kojima T, Ogasawara N, Murata M, kamekura R, Kurose M, Go M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N.
- Journal Title
  
  Mol Pharmacol 74
  
  Pages: 432-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Expression of fascin-1, an actin-binding protein, in migrating hepatoblasts during rat liver development.2008
- Author(s)
  Hayashi Y, Toda K, Saibara T, Okamoto S, Osanai M, Enzan H, Lee GH.
- Journal Title
  
  Cell Tissue Res 334
  
  Pages: 219-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes.2008
- Author(s)
  Kojima T, Takano K, Yamaguchi H, Murata M, Son S, Imamura M, Yamaguchi H, Osanai M, Chiba H, Himi T, Sawada N.
- Journal Title
  
  Liver Int 28
  
  Pages: 534-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy.2008
- Author(s)
  Nishikiori N, Osanai M, Chiba H, Kojima T, Inatomi S, Ohguro H, Sawada N.
- Journal Title
  
  Clinical Ophthalmol 2
  
  Pages: 233-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Transmembrane proteins of tight junctions.2008
- Author(s)
  Chiba H, Osanai M, Murata M, Kojima T, Sawada N.
- Journal Title
  
  Biochim Biophys Acta 1778
  
  Pages: 588-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway.2008
- Author(s)
  Hatakeyama N, Kojima T, Iba K, Murata M, Thi MM, Spray DC, Osanai M, Chiba H, Ishiai S, Yamashita T, Sawada N.
- Journal Title
  
  Cell Tissue Res 334
  
  Pages: 243-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590402
[Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity : Role of retinoic acid receptor alpha agonists in colitis.2007
- Author(s)
  Osanai M et al.
- Journal Title
  
  Mol Pharmacol. 71
  
  Pages: 250-258
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity : Role of retinoic acid receptor alpha agonists in colitis.2007
- Author(s)
  Osanai M et al.
- Journal Title
  
  Mol Pharmacol. 71
  
  Pages: 250-258
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1557-1562
- NAID
  10019997370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.2007
- Author(s)
  Osanai, M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1027-1034
- NAID
  120002187916
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1557-1562
- NAID
  10019997370
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity : Role of retinoic acid receptor alpha agonists in colitis.2007
- Author(s)
  Osanai, M, et. al.
- Journal Title
  
  Mol Pharmacol 71
  
  Pages: 250-258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells.2007
- Author(s)
  Osanai, M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1557-1562
- NAID
  10019997370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1027-1034
- NAID
  120002187916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1027-1034
- NAID
  120002187916
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis.2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Mol Pharmacol 71
  
  Pages: 250-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Cellular retinoic acid bioavailabilily determines epithelial integrity:Role of retinoic acid receptor alpha agonists in colitis2007
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Mol Pharmacol 71
  
  Pages: 250-258
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Cellular retinoic acid bioavailability determines epithelial integrity : Role of retinoic acid receptor alpha agonists in colitis.2007
- Author(s)
  Osanai M et al.
- Journal Title
  
  Mol Pharmacol 71
  
  Pages: 250-258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes.2006
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes2006
- Author(s)
  Osanai M, et. al.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes.2006
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Res 66
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes.2006
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 9125-9133
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes.2006
- Author(s)
  Osanai, M, et. al.
- Journal Title
  
  Cancer Res 66
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Sci. (in press)
- NAID
  120002187916
- Data Source
  KAKENHI-PROJECT-17390117
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Sci (in press)
- NAID
  120002187916
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Sci. in press
- NAID
  120002187916
- Data Source
  KAKENHI-PROJECT-17590308
[Journal Article] Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells.
- Author(s)
  Osanai M et al.
- Journal Title
  
  Cancer Sci. (in press)
- NAID
  120002187916
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590308
[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、舌癌の悪性化に関与する。2023
- Author(s)
  桑原未羽黒田睦喜小野佑輔髙澤啓及能大輔真柄和史青山智志髙澤久美小山内誠
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06983
[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、膵癌細胞の悪性形質の促進に関与する。2022
- Author(s)
  井上彩乃小野佑輔高澤啓及能大輔真柄和史青山智志高澤久美小山内誠
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06983
[Presentation] 平滑筋肉腫の FFPE 組織標本を用いた新規バイオマーカー探索の試み2019
- Author(s)
  高澤啓，小山内誠（共同演者，他6名）
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] レチノイン酸代謝を起点として理解する多彩な病態と新しい治療戦略の創出2019
- Author(s)
  小山内誠
- Organizer
  第52回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] Claudin-18 はEGFR/ERK 経路を介して胆道癌悪性化に関与する2019
- Author(s)
  高澤啓，小山内誠（共同演者，他4名）
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 子宮頸部腺癌におけるJAM-Aの発現とその臨床病理学的意義2019
- Author(s)
  村上太郎，小山内誠（共同演者，他8名）
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] CYP24A1-induced Vitamin D Insufficiency Promotes Breast Cancer Growth2019
- Author(s)
  小山内誠（共同演者，他6名）
- Organizer
  2019年　アメリカ癌学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] タイト結合分子Claudin-18の乳癌における発現意義2019
- Author(s)
  小野佑介，小山内誠（共同演者，他6名）
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] Vasculogenic mimicry in gastrointestinal stromal tumor of the stomach2019
- Author(s)
  佐藤みどり，小山内誠（共同演者，他7名）
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 平滑筋肉腫の FFPE 組織標本を用いた新規バイオマーカー探索の試み2019
- Author(s)
  高澤啓，小山内誠（共同演者，他4名）
- Organizer
  第52回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 子宮頸部腺癌におけるJAM-Aの発現とその臨床病理学的意義2018
- Author(s)
  村上太郎，小山内誠（共同演者，他5名）
- Organizer
  2018年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] Claudin-18 はEGFR/ERK 経路を介して胆道癌悪性化に関与する2018
- Author(s)
  高澤啓，小山内誠（共同演者）
- Organizer
  2018年　日本癌学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 平滑筋肉腫の FFPE 組織標本を用いた新規バイオマーカー探索の試み2018
- Author(s)
  高澤啓，小山内誠（共同演者，他4名）
- Organizer
  2018年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 子宮頸部腺癌におけるALDOAの発現解析2018
- Author(s)
  斎藤佑樹，小山内誠（共同演者，他4名）
- Organizer
  2018年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 平滑筋肉腫の FFPE 組織標本を用いた新規バイオマーカー探索の試み2017
- Author(s)
  高澤啓，小山内誠（共同演者，他5名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] CYP24A1-indiced vitamin D insufficiency promotes breast cancer growth2017
- Author(s)
  Osanai M, Takasawa A, Takasawa K, Murata M, Sawada N
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 慢性膿胸を背景に発症した両側副腎原発 NK/T 細胞性リンパ腫の一剖検例2017
- Author(s)
  河田由香，小山内誠（共同演者，他5名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] Claudin-18 はEGFR/ERK 経路を介して胆道癌悪性化に関与する2017
- Author(s)
  高澤啓，小山内誠，澤田典均
- Organizer
  2017年　日本癌学会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 乳癌におけるタイト結合関連タンパク質 LSR の発現とその意義2017
- Author(s)
  太田未咲，小山内誠（共同演者，他5名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] ランゲルハンス細胞肉腫を含む五重癌の一例2017
- Author(s)
  山本晃匡，小山内誠（共同演者，他6名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 子宮頸部腺癌における ALDOA の発現とその臨床病理学的意義2017
- Author(s)
  齋藤裕己，小山内誠（共同演者，他6名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] 原因蛋白質同定に難渋した心アミロイドーシスの 1 剖検例2017
- Author(s)
  上田朝子，小山内誠（共同演者，他5名）
- Organizer
  2017年　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08697
[Presentation] ニコチンはレチノイン酸代謝酵素CYP26A1の発現を低下させ乳癌の進行を抑制する2013
- Author(s)
  小山内誠、李康弘
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23501324
[Presentation] レチノイン酸代謝酵素CYP26A1は乳癌で高発現している2010
- Author(s)
  小山内誠、李康弘
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-20590402
[Presentation] レチノイン酸代謝酵素CYP26A1の癌遺伝子としての役割2010
- Author(s)
  小山内誠
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590402
[Presentation] レチノイン酸代謝酵素CYP26A1は乳癌で高発現している2010
- Author(s)
  小山内誠
- Organizer
  日本病理学会総会
- Place of Presentation
  東京都新宿区京王プラザホテル
- Year and Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-20590402
[Presentation] レチノイン酸代謝酵素CYP26A1の癌遺伝子としての役割2010
- Author(s)
  小山内誠、李康弘
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590402

1. KOJIMA Takashi (30260764)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. LEE Gang-Hong (10261405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. MASUDA Sonoko (90157206)

# of Collaborated Projects: 1 results

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4. TANAKA Takuji (40126743)

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5. TERASAKI Masaru (10391195)

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6. CHIBA Hideki (00295346)

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7. TOBIOKA Hrotoshi (90291559)

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8. MURATA Masaki (10404592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 澤田典均 (30154149)

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# of Collaborated Products: 0 results
10. 小野佑輔 (90812355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. 高澤啓 (00593021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
12. TAKASAWA KUMI

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# of Collaborated Products: 4 results
13. AKIMOTO TAISHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 沢田典均

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
15. 青山智志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 山本英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
17. 須藤豪太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 畠中柚衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 高澤久美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 高田弘一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Osanai Makoto 小山内 誠

小山内 誠 オサナイ マコト

OSANAI Makoto 小山内 誠

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レチノイン酸欠乏状態の腎メサンギウム細胞を起点に理解する新しい糖尿病性腎症の病理Principal Investigator

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レチノイン酸特異的代謝酵素CYP26のレチノイン酸非依存性がん悪性化機構の解明

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Retinoic acid-deficient renal mesangial cells are responsible for the development of diabetic nephropathyPrincipal Investigator

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Nuclear receptors as molecular regulator and chemopreventive targets of colon cancer stem cells.

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Retinoic acid metabolizing enzyme CYP26A1 is a candidate oncogene, and a possible therapeutic target for cancers.Principal Investigator

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Biological barrier and human diseasesPrincipal Investigator

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Regulation of bile canalicular barrier by a novel tight junction protein claudin-2 during cholestasis

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[Book] The tight junction, intercellular seal as a cell-signaling player - Protocols for examination for its status.(Turksen K (Ed.))2010

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[Book] Tight junctions.(Schwab M (Ed.))2009

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[Book] Encyclopedia of Cancer2007

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[Journal Article] Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas2024

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[Journal Article] Invasive pulmonary aspergillosis with candidiasis: usefulness of molecular and ultrastructural morphological analysis on FFPE tissue for invasive fungal infections2023

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[Journal Article] Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series2023

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[Journal Article] Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers.2023

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[Journal Article] A novel approach to diagnosing crystal-storing histiocytosis: utility of scanning electron microscopy for formalin-fixed paraffin-embedded tissue specimens2023

Osanai Makoto 小山内誠

小山内誠オサナイマコト

OSANAI Makoto 小山内誠