Iwata Shigeru 岩田慈

… Alternative Names

岩田慈イワタシゲル

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Researcher Number	60389434
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 准教授 2025: 産業医科大学, 医学部, 非常勤医師
Affiliation (based on the past Project Information) *help	2025: 和歌山県立医科大学, 医学部, 准教授 2022 – 2023: 和歌山県立医科大学, 医学部, 准教授 2020 – 2021: 産業医科大学, 医学部, 講師 2016 – 2019: 産業医科大学, 医学部, 助教 2012: 産業医科大学, 医学部, 助教 2005 – 2006: 産業医科大学, 医学部, 専門修練医
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator SLE / B細胞 / 免疫代謝 / mTORC1 / 免疫細胞代謝 / B cell / モノアミン / HVA / SDF-1α / SCGF-1β … More / NPSLE / 全身性エリテマトーデス / 必須アミノ酸 / RA / mTOR / 自己免疫疾患 / 細胞内代謝システム / リンパ球 / IFN / 解糖系 / AMPK / T-bet / T細胞 / STAT1 / IL-21 / Btk / 線維芽細胞 / FGF-2 / ヘパラン硫酸プロテオグリカン / 関節リウマチ … More Except Principal Investigator 全身性エリテマトーデス / CD73 / アデノシン / Bリンパ球 / ANCA関連血管炎 / シェーグレン症候群 / 補体 / B細胞 / 機能的磁気共鳴画像法 / 液性因子 / 自己抗体 / 神経精神ループス / モノアミン / 核磁気共鳴画像 / サイトカイン / 中枢神経障害 Less

SLEにおけるCD73シグナル異常とBリンパ球分化への影響～新規治療層別化因子の解明～
- Principal Investigator
  
  永安敦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Differentiation of age-associated B cells through ZEB2, immunometabolism, and immunosenescence in SLEPrincipal Investigator
- Principal Investigator
  
  岩田慈
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Wakayama Medical University
全身性エリテマトーデスにおけるB細胞-補体連関の機序解明と病態制御への展開
- Principal Investigator
  
  松宮遼
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Wakayama Medical University
Effects of autoantibodies and inflammatory mediators in cerebrospinal fluid on brain activity in patients with neuropsychiatric systemic lupus erythematosus
- Principal Investigator
  
  藤井隆夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Wakayama Medical University
神経精神ループスにおける生理活性物質不均衡、B細胞分化異常を介した病態機構の解明Principal Investigator
- Principal Investigator
  
  岩田慈
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Wakayama Medical University
Mechanism of human B cell differentiation via amino-acid metabolism -Development of novel therapy for systemic lupus erythematosus-Principal Investigator
- Principal Investigator
  
  Iwata Shigeru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The regulation of metabolic system by IFN and its involvement in B cell and T cell differentiation: new therapeutic strategy for SLEPrincipal Investigator
- Principal Investigator
  
  Iwata Shigeru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Occupational and Environmental Health, Japan
Btkを標的としたSLEの新規治療開発および同分子による分子生物学的評価法の確立Principal Investigator
- Principal Investigator
  
  岩田慈
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
ヘパラン硫酸糖鎖伸長を標的とした関節リウマチ治療の新戦略Principal Investigator
- Principal Investigator
  
  岩田慈
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2023 2022 2021 2020 2019 2018 2017 2016 2012

All Journal Article Presentation Book

[Book] 臨床免疫・アレルギー科2012
- Author(s)
  岩田慈
- Total Pages
  596
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24791016
[Journal Article] Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus2023
- Author(s)
  Yuya Fujita
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 62 Issue: 10 Pages: 3490
- DOI
  10.1093/rheumatology/kead091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08525, KAKENHI-PROJECT-22K08574
[Journal Article] B cell activation via immunometabolism in systemic lupus erythematosus2023
- Author(s)
  Shigeru Iwata, Maiko Hajime Sumikawa, Yoshiya Tanaka
- Journal Title
  
  Frontiers in immunology
  
  Volume: 14 Pages: 1155421-1155421
- DOI
  10.3389/fimmu.2023.1155421
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08574
[Journal Article] Association of Viral Infection With the Development and Pathogenesis of Systemic Lupus Erythematosus2022
- Author(s)
  Iwata Shigeru、Tanaka Yoshiya
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9
- DOI
  10.3389/fmed.2022.849120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] A Case of Simultaneous Onset of Highly Active Systemic Lupus Erythematosus and IgG4-Related Renal Disease2022
- Author(s)
  Fujita Yuya、Iwata Shigeru、Nakano Kazuhisa、Nakayamada Shingo、Miyazaki Yusuke、Kawabe Akio、Korekoda-Yoshinari Hiroko、Nawata Aya、Tanaka Yoshiya
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: - Issue: 2 Pages: 178-182
- DOI
  10.1093/mrcr/rxac002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] An enhanced mitochondrial function through glutamine metabolism in plasmablast differentiation in systemic lupus erythematosus2022
- Author(s)
  Maiko Hajime Sumikawa, Shigeru Iwata, Mingzeng Zhang, Hiroko Miyata, Masanobu Ueno, Yasuyuki Todoroki, Atsushi Nagayasu, Ryuichiro Kanda, Koshiro Sonomoto, Keiichi Torimoto, Seunghyun Lee, Shingo Nakayamada, Kazuo Yamamoto, Yosuke Okada, Yoshiya Tanaka
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 7 Pages: 1-11
- DOI
  10.1093/rheumatology/keab824
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-20K17524, KAKENHI-PROJECT-21K20884
[Journal Article] Efficacy and safety of high-dose of mycophenolate mofetil compared with cyclophosphamide pulse therapy as induction therapy in Japanese patients with proliferative lupus nephritis2021
- Author(s)
  Ohkubo Naoaki、Iwata Shigeru、Nakano Kazuhisa、Miyagawa Ippei、Hanami Kentaro、Fukuyo Shunsuke、Miyazaki Yusuke、Kawabe Akio、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 6 Pages: 1077-1085
- DOI
  10.1093/mr/roab113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-19K08926
[Journal Article] 自己免疫疾患におけるB細胞の役割と新規治療戦略2021
- Author(s)
  岩田　慈, 田中　良哉
- Journal Title
  
  医学のあゆみ
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors2021
- Author(s)
  Zhang Mingzeng、Iwata Shigeru、Sonomoto Koshiro、Ueno Masanobu、Fujita Yuya、Anan Junpei、Miyazaki Yusuke、Ohkubo Naoaki、Sumikawa Maiko Hajime、Todoroki Yasuyuki、Miyata Hiroko、Nagayasu Atsushi、Kanda Ryuichiro、Hao He、Trimova Gulzhan、Lee Seunghyun、Nakayamada Shingo、Sakata Kei、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 7 Pages: 3010-3022
- DOI
  10.1093/rheumatology/keab834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis.2021
- Author(s)
  Iwata S, Zhang M, Hajime M, Ohkubo N, Sonomoto K, Torimoto K, Kitanaga Y, Trimova G, Todoroki Y, Miyata H, Ueno M, Nagayasu A, Kanda R, Nakano K, Nakayamada S, Sakata K, Tanaka Y.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: in press Issue: 11 Pages: 5452-5462
- DOI
  10.1093/rheumatology/keab229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Therapeutic perspectives on the metabolism of lymphocytes in patients with rheumatoid arthritis and systemic lupus erythematosus2021
- Author(s)
  Shigeru Iwata, Yoshiya Tanaka
- Journal Title
  
  Expert Rev Clin Immunol.
  
  Volume: 17 Issue: 10 Pages: 1121-1130
- DOI
  10.1080/1744666x.2021.1964957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] ヒトB細胞分化におけるアミノ酸を介した免疫代謝機構の解明～SLE新規治療の創出～2021
- Author(s)
  岩田　慈, 田中　良哉
- Journal Title
  
  アレルギーの臨床.
  
  Volume: 41(2) Pages: 50-54
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Neuropsychiatric systemic lupus erythematosus detected using extravascular spillage signal on dynamic magnetic resonance imaging (Ktrans)2021
- Author(s)
  Fujita Yuya、Iwata Shigeru、Nakano Kazuhisa、Adachi Hiroaki、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: 61 Issue: SI Pages: SI102-SI104
- DOI
  10.1093/rheumatology/keab757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Methionine commits cells to differentiate into plasmablasts through epigenetic regulation of BTB and CNC homolog 2 by the methyltransferase enhancer of zeste homolog 2.2020
- Author(s)
  Zhang M, Iwata S, Hajime M, Ohkubo N, Todoroki Y, Miyata H, Ueno M, Hao H, Zhang T, Fan J, Nakayamada S, Yamagata K, Tanaka Y.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: － Issue: 7 Pages: 1143-1153
- DOI
  10.1002/art.41208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-19K08925
[Journal Article] Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-γ Overproduction in T Helper 1 Cells2020
- Author(s)
  Iwata Shigeru、Zhang Mingzeng、Hao He、Trimova Gulzhan、Hajime Maiko、Miyazaki Yusuke、Ohkubo Naoaki、Satoh Kanda Yurie、Todoroki Yasuyuki、Miyata Hiroko、Ueno Masanobu、Nagayasu Atsushi、Nakayamada Shingo、Sakata Kei、Tanaka Yoshiya
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 593103-593103
- DOI
  10.3389/fimmu.2020.593103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Metabolic Reprogramming Commits Differentiation of Human CD27+IgD+ B Cells to Plasmablasts or CD27-IgD- Cells.2017
- Author(s)
  9.Torigoe M, Iwata S, Nakayamada S, Sakata K, Zhang M, Hajime M, Miyazaki Y, Narisawa M, Ishii K, Shibata H, Tanaka Y.
- Journal Title
  
  The Journal of immunology
  
  Volume: 199 Issue: 2 Pages: 425-434
- DOI
  10.4049/jimmunol.1601908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09928
[Journal Article] Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation.2012
- Author(s)
  岩田慈
- Journal Title
  
  The journal of allergy and clinical immunology
  
  Volume: 129 Pages: 1594-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791016
[Presentation] 間質性肺疾患を合併した関節リウマチ患者の病態と治療戦略2023
- Author(s)
  岩田　慈
- Organizer
  日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08574
[Presentation] 自己免疫疾患におけるB細胞の役割と最近の話題～関節リウマチ、全身性エリテマトーデスを中心に～2023
- Author(s)
  岩田　慈
- Organizer
  日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08574
[Presentation] RA患者におけるmTOR活性化CD8+細胞の病態への関与と生物学的製剤が与える影響2021
- Author(s)
  岩田慈、張明増、上野匡庸、藤田悠哉、隅川舞子、大久保直紀、轟泰幸、宮田寛子、永安敦、神田龍一郎、中野和久、中山田真吾、阪田圭、田中良哉
- Organizer
  第65回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Neuropsychiatric Systemic Lupus Erythematosus (NPSLE)の新規評価法確立に向けた取り組み～LOOPS registryから～2021
- Author(s)
  岩田慈, 藤田悠哉, 秀瀬真輔, 石渡小百合, 園本格士朗, 大久保直紀中野和久, 中山田真吾, 服部功太郎, 功刀浩, 吉村玲児, 田中良哉
- Organizer
  2021年日本生物学的精神医学会/日本神経精神薬理学会(合同年会)
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] The relevance of mTOR activation in CD8+ cells to disease activity and therapeutic response to TNF inhibitor in patients with rheumatoid arthritis2021
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Koshiro Sonomoto, Masanobu Ueno, Yuya Fujita, Naoaki Ohkubo, Maiko Hajime, Yasuyuki Todoroki, Hiroko Miyata, Atsushi Nagayasu, Ryuichiro Kanda, Gulzhan Trimova, Shingo Nakayamada, and Yoshiya Tanaka
- Organizer
  第49回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] 自己免疫疾患における免疫代謝機構を介したリンパ球分化・機能発現と病態への関与2021
- Author(s)
  岩田慈、田中良哉
- Organizer
  第49回臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] 全身性エリテマトーデス (SLE)におけるリンパ球免疫代謝異常と病態への関与2020
- Author(s)
  岩田慈、田中良哉
- Organizer
  第48回日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Role of amino acid cystine in cytotoxic effects of CD8+ cells and the relevance to pathological processes of rheumatoid arthritis2020
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Kazuhisa Nakano, Shingo Nakayamada, Kaoru Yamagata, Kei Sakjata and Yoshiya Tanaka
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] The relevance of mTORC1-phosphorylated CXCR3+ memory B cells to the pathogenesis of rheumatoid arthritis2020
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Yukihiro Kitanaga, Gulzhan Torimova, Kazuhisa Nakano, Shingo Nakayamada, Kaoru Yamagata, Kei Sakata and Yoshiya Tanaka
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Methionine commits immunometabolism and epigenetic regulation of BACH2 loci in B cells, resulting in biases toward plasmablast differentiation in the pathogenesis of SLE2019
- Author(s)
  Mingzeng Zhang, Shigeru Iwata, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Jie Fan, Shingo Nakayamada, Kaoru Yamagata and Yoshiya Tanaka
- Organizer
  American college of rheumatology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] 必須アミノ酸メチオニンによるEZH2発現を介した形質芽細胞分化誘導とSLE病態への関与2019
- Author(s)
  張明増、岩田慈、元舞子、大久保直紀、轟泰幸、宮田　寛子、中山田真吾、山形薫、田中良哉
- Organizer
  日本臨床免疫学会 2019
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Role of methionine and its transporter CD98 in human B cell differentiation and the relevance to pathological processes of SLE2019
- Author(s)
  Mingzeng Zhang, Shigeru Iwata, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Jie Fan, Shingo Nakayamada, Kaoru Yamagata and Yoshiya Tanaka
- Organizer
  EAGOR 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Role of methionine in human B cell differentiation and the relevance to pathological processes of SLE2019
- Author(s)
  張明増、岩田慈、元舞子、大久保直紀、轟泰幸、宮田　寛子、中山田真吾、山形薫、田中良哉
- Organizer
  日本免疫毒性学会 2019
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] ヒトB細胞分化における免疫代謝の役割と自己免疫病態への関与2018
- Author(s)
  岩田慈、田中良哉
- Organizer
  日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] mTORC1 phosphorylation in CXCR3+ memory B cells and its relevance to the pathogenesis of rheumatoid arthritis2018
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Maiko Hajime, Jie Fan, Kei Sakata, Naoaki Ohkubo, Kazuhisa Nakano, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] IFN-γ-T-betを介したCD4+T細胞代謝変容とSLE病態への関与2018
- Author(s)
  岩田慈、張明増、元舞子、阪田圭、山形薫、中山田真吾、田中良哉
- Organizer
  日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] Metabolic reprogramming in CD4+CD28-CXCR3intT-bethi cells and its relevance to pathogenesis in patients with SLE2017
- Author(s)
  Shigeru Iwata, Kei Sakata, Maiko Hajime, Masataka Torigoe, Naoaki Ohkubo, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  LUPUS2017
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] IFN-γ-T-betを介したTh1細胞代謝変容とSLE病態への関与2017
- Author(s)
  岩田慈、菅野由香、阪田圭、元舞子、張明増、中山田真吾、John J. O’Shea, 田中良哉
- Organizer
  第45回　日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] IFN-γ-T-bet mediated metabolic reprograming in T helper 1 cells and its relevance to pathogenesis of SLE2017
- Author(s)
  Shigeru Iwata, Yuka Kanno, Kei Sakata, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Shingo Nakayamada, John J O’Shea and Yoshiya Tanaka
- Organizer
  第46回免疫学会
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] ABNORMAL B CELL ACTIVATION THROUGH CELLULAR METABOLIC REPROGRAMMING AND ITS RELEVANCE TO THE PATHOGENESIS OF SLE.2016
- Author(s)
  Masataka Torigoe, Shigeru Iwata, Kei Sakata, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  EULAR2016
- Place of Presentation
  London, UK
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] IFNsのT-betを介したT細胞代謝リプログラミングと自己免疫疾患への関与2016
- Author(s)
  岩田慈、菅野由香、阪田圭、中山田真吾、John J. O’Shea, 田中良哉
- Organizer
  第44回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル、東京都新宿区
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] 自己免疫疾患におけるB細胞代謝リプログラミングと病態への関与2016
- Author(s)
  岩田慈、鳥越雅隆、阪田圭、元舞子、中山田真吾、田中良哉
- Organizer
  第44回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル、東京都新宿区
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] Metabolic reprogramming in CD4+CD28-CXCR3intT-bethi cells and its relevance to pathogenesis of SLE2016
- Author(s)
  Shigeru Iwata, Masataka Torigoe, Naoaki Ohkubo, Maiko Hajime, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、沖縄県宜野湾市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K09928
[Presentation] 難治性SLEに対する抗CD20および抗CD22抗体療法2012
- Author(s)
  岩田慈
- Organizer
  日本リウマチ学会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)(招待講演)
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-24791016

1. 田中良哉 (30248562)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. 藤井隆夫 (70255462)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 金桶吉起 (20280589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 藏本伸生 (70444461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 松宮遼 (20795372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 井上徳光 (80252708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 永安敦 (40768561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Iwata Shigeru 岩田 慈

岩田 慈 イワタ シゲル

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SLEにおけるCD73シグナル異常とBリンパ球分化への影響～新規治療層別化因子の解明～

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Differentiation of age-associated B cells through ZEB2, immunometabolism, and immunosenescence in SLEPrincipal Investigator

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全身性エリテマトーデスにおけるB細胞-補体連関の機序解明と病態制御への展開

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Effects of autoantibodies and inflammatory mediators in cerebrospinal fluid on brain activity in patients with neuropsychiatric systemic lupus erythematosus

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神経精神ループスにおける生理活性物質不均衡、B細胞分化異常を介した病態機構の解明Principal Investigator

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Mechanism of human B cell differentiation via amino-acid metabolism -Development of novel therapy for systemic lupus erythematosus-Principal Investigator

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The regulation of metabolic system by IFN and its involvement in B cell and T cell differentiation: new therapeutic strategy for SLEPrincipal Investigator

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Btkを標的としたSLEの新規治療開発および同分子による分子生物学的評価法の確立Principal Investigator

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ヘパラン硫酸糖鎖伸長を標的とした関節リウマチ治療の新戦略Principal Investigator

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[Book] 臨床免疫・アレルギー科2012

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[Journal Article] Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus2023

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[Journal Article] B cell activation via immunometabolism in systemic lupus erythematosus2023

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[Journal Article] Association of Viral Infection With the Development and Pathogenesis of Systemic Lupus Erythematosus2022

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[Journal Article] A Case of Simultaneous Onset of Highly Active Systemic Lupus Erythematosus and IgG4-Related Renal Disease2022

Iwata Shigeru 岩田慈

岩田慈イワタシゲル

[Presentation] 自己免疫疾患におけるB細胞の役割と最近の話題～関節リウマチ、全身性エリテマトーデスを中心に～2023