akagawa hiroyuki 赤川浩之

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AKAGAWA Hiroyuki 赤川浩之

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Researcher Number	60398807
Other IDs
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 東京女子医科大学, 医学部, 准教授 2016 – 2023: 東京女子医科大学, 医学部, 准教授 2011 – 2015: 東京女子医科大学, 医学部, テニュアトラック准教授 2013: 東京女子医科大学, 医学部, 准教授 2012 – 2013: 東京女子医科大学, 医学部, テニｭアトラｯク准教授 2007 – 2010: Tokyo Women's Medical University, 医学部, 助教 2005 – 2006: 東京女子医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Cerebral neurosurgery / Basic Section 45010:Genetics-related / Basic Section 56010:Neurosurgery-related / Neurosurgery / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 感受性遺伝子 / もやもや病 / 脳動脈瘤 / 類もやもや病 / 遺伝子 / ハプロタイプ / LIMK1 / ELN / プロスタサイクリン合成酵素 / 遺伝性疾患 … More / 特発性頚部内頚動脈攣縮症 / 遺伝的修飾因子 / RNF213 / 全エクソームシーケンシング / もやもや症候群 / 脳神経疾患 / 次世代シーケンサー / レアバリアント / CCER2遺伝子 / RNF213遺伝子 / 連鎖不平衡 / rare variant / gene-gene interaction / COL1A2 / LOXL family genes / LOX family genes / 一塩基多型 / プロモーター / くも膜下出血 … More Except Principal Investigator 脳動脈瘤 / aneurysm / 遺伝子 / 次世代シーケンサー / 感受性遺伝子 / 網羅的 / 機能解析 / 若年発症糖尿病 / monogenic diabetes / レアバリアント / RNF213 / 遺伝解析 / もやもや病 / くも膜下出血 / subarachnoid hemorrhage / 腎動脈狭窄症 / 冠動脈狭窄症 / 末梢性肺動脈狭窄症 / 肺動脈性肺高血圧症 / 全ゲノム解析 / CDKN2A/B欠失 / TERTプロモーター変異 / 1p/19q欠失 / IDH変異 / リアルタイムPCR / 神経膠種 / 術中遺伝子診断 / WES / MODY / 発症機序 / シーケンス / genetics / RNF213遺伝子 / RN213 / 脳腫瘍学 / 再発 / 腫瘍幹細胞 / myc / エピジェネティクス / 膠芽腫 / anti tumor effect / cMyc / stem cell / glioblastoma / 多発性のう胞腎 / 家族性 / familial / gene / subarachnoid hemorrhge / genome / microarray / gene expression / ゲノム / マイクロアレイ / 遺伝子発現 / 高速ｼｰｹﾝｻｰ / ターゲットリシーケンス / ハプロタイプ / ゲノムワイド連鎖解析 / SNP / Identity-by-descent / 遺伝子解析 / 脳血管 / 脳動脈 / 腎動脈 / イヌ / 高血圧 / rupture / development / initiation / model / canine / cerebral aneurysm Less

A comprehensive genomic investigation of monogenic diabetes via whole-genome sequencing
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Tokyo Women's Medical University
PTGIS遺伝子異常がもたらす、中小動脈疾患の病態解明
- Principal Investigator
  
  永井礼子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hokkaido University
特発性頚部内頚動脈攣縮症の遺伝子改変モデルラットを用いた病態解明研究Principal Investigator
- Principal Investigator
  
  赤川浩之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Women's Medical University
システマチックアプローチによるMonogenic diabetes発症機序の解明
- Principal Investigator
  
  岩崎直子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  Tokyo Women's Medical University
リアルタイムPCRを用いた術中迅速遺伝子診断による新たな神経膠腫手術戦略の確立
- Principal Investigator
  
  新田雅之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Women's Medical University
Next-generation sequencing of moyamoya syndromePrincipal Investigator
- Principal Investigator
  
  Hiroyuki Akagawa
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Women's Medical University
Analysis of rare variants in RNF213 in patients of cerebral aneurysm
- Principal Investigator
  
  Kasuya Hidetoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Tokyo Women's Medical University
Identification of novel susceptibility genes associated with moyamoya disease without pathogenic variants in RNF213Principal Investigator
- Principal Investigator
  
  Akagawa Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Women's Medical University
Development of new therapeutic strategies to prevent stem cell formation of glioblastoma by epigenetics control
- Principal Investigator
  
  Nitta Masayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Women's Medical University
Identification of susceptible genes by genome-wide genetic analysis in patients with familial aneurysms
- Principal Investigator
  
  Kasuya Hidetoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Women's Medical University
Resequencing analysis of the 19q25.3 locus associated with Moyamoya disease in JapanPrincipal Investigator
- Principal Investigator
  
  Akagawa Hiroyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  Tokyo Women's Medical University
Next generation sequencing of a large pedigree with intracranial aneurysms
- Principal Investigator
  
  KASUYA HIDETOSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
Genetic analysis of familial moyamoya disease using next generation sequencer
- Principal Investigator
  
  ONDA HIDEAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
Next generation sequencing of susceptibility loci for intracranial aneurysms to identify disease-causal mutationsPrincipal Investigator
- Principal Investigator
  
  AKAGAWA Hiroyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
Mechanism of initiation and development of cerebral aneurysm : Using cerebral aneurysm model
- Principal Investigator
  
  KASUYA Hidetoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
Association of LOXL3 single nucleotide polymorphisms with susceptibility to intracranial aneurysms.Principal Investigator
- Principal Investigator
  
  AKAGAWA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
脳動脈瘤感受性遺伝子Elastin、LIM kinaselからの責任変異同定Principal Investigator
- Principal Investigator
  
  赤川浩之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University
Microarray analysis for cerebral aneurysm-by using the information of genome
- Principal Investigator
  
  KASUYA Hidetoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Tokyo Women's Medical University

[Book] 医学と薬学2018
- Author(s)
  赤川　浩之
- Total Pages
  8
- Publisher
  【日常診療でよく目にする脳外科疾患(II)】脳神経外科領域の遺伝子診断
- Data Source
  KAKENHI-PROJECT-18K08953
[Book] 医学と薬学【日常診療でよく目にする脳外科疾患(II)】脳神経外科領域の遺伝子診断2018
- Author(s)
  赤川浩之
- Total Pages
  8
- Publisher
  (株)自然科学社
- Data Source
  KAKENHI-PROJECT-16K10740
[Book] 第6章．脳動脈瘤の遺伝解析、『未破裂脳動脈瘤 Japan standard』2015
- Author(s)
  広田健吾, 赤川浩之, 糟谷英俊．
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K10316
[Journal Article] Identification of Prostaglandin I2 Synthase Rare Variants in Patients With Williams Syndrome and Severe Peripheral Pulmonary Stenosis2024
- Author(s)
  Chida‐Nagai Ayako、Akagawa Hiroyuki、Sawai Saori、Ma Yue‐Jiao、Yakuwa Satoshi、Muneuchi Jun、Yasuda Kazushi、Yamazawa Hirokuni、Yamamoto Toshiyuki、Takakuwa Emi、Tomaru Utano、Furutani Yoshiyuki、Kato Tatsuya、Harada Gen、Inai Kei、Nakanishi Toshio、Manabe Atsushi、Takeda Atsuhito、Jing Zhi‐Cheng
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 13 Issue: 9
- DOI
  10.1161/jaha.123.032872
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08576
[Journal Article] A novel pathogenic variant in the glucokinase gene found in two Japanese siblings with maturity-onset diabetes of the young 22023
- Author(s)
  Satoshi Tanaka, Hiroyuki Akagawa, Kenkou Azuma, Kaoru Watanabe, Sayaka Higuchi, Naoko Iwasaki
- Journal Title
  
  Endocr J
  
  Volume: 70 Issue: 6 Pages: 629-634
- DOI
  10.1507/endocrj.EJ22-0541
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06281
[Journal Article] Triple bypass for multisystem smooth muscle dysfunction syndrome due to Arg179His ACTA2 mutation2022
- Author(s)
  Morita Shuhei、Yamaguchi Koji、Akagawa Hiroyuki、Ishikawa Tatsuya、Funatsu Takayuki、Eguchi Seiichirou、Ishikawa Tomomi、Niwa Akihiro、Nonaka Taku、Kawamata Takakazu
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 31 Issue: 9 Pages: 106402-106402
- DOI
  10.1016/j.jstrokecerebrovasdis.2022.106402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09537
[Journal Article] Absence of the RNF213 p.R4810K variant may indicate a severe form of pediatric moyamoya disease in Japanese patients2022
- Author(s)
  Hara Shoko、Mukawa Maki、Akagawa Hiroyuki、Thamamongood Thiparpa、Inaji Motoki、Tanaka Yoji、Maehara Taketoshi、Kasuya Hidetoshi、Nariai Tadashi
- Journal Title
  
  Journal of Neurosurgery: Pediatrics
  
  Volume: 29 Issue: 1 Pages: 48-56
- DOI
  10.3171/2021.7.peds21250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09341, KAKENHI-PROJECT-19K09537
[Journal Article] RNF213 Gene Variants in Moyamoya Disease: Questions Remain Unanswered2022
- Author(s)
  Hara Shoko、Akagawa Hiroyuki、Nariai Tadashi
- Journal Title
  
  World Neurosurgery
  
  Volume: 162 Pages: 18-20
- DOI
  10.1016/j.wneu.2022.03.040
- Data Source
  KAKENHI-PROJECT-19K09537
[Journal Article] Can Moyamoya Disease Susceptibility Gene Affect Extracranial Systemic Artery Stenosis?2020
- Author(s)
  Nomura Shunsuke、Aihara Yasuo、Akagawa Hiroyuki、Chiba Kentaro、Yamaguchi Koji、Kawashima Akitsugu、Okada Yoshikazu、Kawamata Takakazu
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 29 Issue: 2 Pages: 104532-104532
- DOI
  10.1016/j.jstrokecerebrovasdis.2019.104532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09537
[Journal Article] Radiofrequency ablation for DYT‐28 dystonia: short term follow‐up of three adult cases2020
- Author(s)
  Horisawa Shiro、Azuma Kenkou、Akagawa Hiroyuki、Nonaka Taku、Kawamata Takakazu、Taira Takaomi
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 7 Issue: 10 Pages: 2047-2051
- DOI
  10.1002/acn3.51170
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09537, KAKENHI-PROJECT-20K17942, KAKENHI-PROJECT-18K16575
[Journal Article] Surgical Options and Genetic Screening of a Patient With Moyamoya Disease Harboring the RNF213 p.R4180 K Homozygous Variant2020
- Author(s)
  Nomura Shunsuke、Akagawa Hiroyuki、Yamaguchi Koji、Kawashima Akitsugu、Kawamata Takakazu
- Journal Title
  
  Journal of Child Neurology
  
  Volume: 35 Issue: 9 Pages: 621-622
- DOI
  10.1177/0883073820913373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09537
[Journal Article] Genotype-Phenotype Correlation in Long-Term Cohort of Japanese Patients with Moyamoya Disease2019
- Author(s)
  Nomura Shunsuke、Yamaguchi Koji、Akagawa Hiroyuki、Kawashima Akitsugu、Moteki Yosuke、Ishikawa Tatsuya、Aihara Yasuo、Saito Taiichi、Okada Yoshikazu、Kawamata Takakazu
- Journal Title
  
  Cerebrovascular Diseases
  
  Volume: In press Issue: 3-4 Pages: 1-7
- DOI
  10.1159/000499699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10740, KAKENHI-PROJECT-19K09537
[Journal Article] Rare and Low-Frequency Variants in RNF213 Confer Susceptibility to Moyamoya Syndrome Associated with Hyperthyroidism2019
- Author(s)
  Nomura Shunsuke、Akagawa Hiroyuki、Yamaguchi Koji、Ishikawa Tatsuya、Kawashima Akitsugu、Kasuya Hidetoshi、Mukawa Maki、Nariai Tadashi、Maehara Taketoshi、Okada Yoshikazu、Kawamata Takakazu
- Journal Title
  
  World Neurosurgery
  
  Volume: In press Pages: e460-e466
- DOI
  10.1016/j.wneu.2019.03.172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10740, KAKENHI-PROJECT-17K16629
[Journal Article] Rare and low-frequency variants in RNF213 confer susceptibility to moyamoya syndrome associated with hyperthyroidism.2019
- Author(s)
  Nomura S, Akagawa H, Kasuya H, et al.
- Journal Title
  
  World Neurosurgery
  
  Volume: pii: 1878-8750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08953
[Journal Article] Novel and recurrent RNF213 variants in Japanese pediatric patients with moyamoya disease2018
- Author(s)
  Akagawa Hiroyuki、Mukawa Maki、Nariai Tadashi、Nomura Shunsuke、Aihara Yasuo、Onda Hideaki、Yoneyama Taku、Kudo Takumi、Sumita Kazutaka、Maehara Taketoshi、Kawamata Takakazu、Kasuya Hidetoshi
- Journal Title
  
  Human Genome Variation
  
  Volume: 5 Issue: 1 Pages: 17060-17060
- DOI
  10.1038/hgv.2017.60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10740, KAKENHI-PROJECT-17K16629
[Journal Article] Letter to the Editor. Influence of rare RNF213 variants other than p.R4810K on the clinical outcomes of moyamoya disease2018
- Author(s)
  Shunsuke Nomura, Akitsugu Kawashima, Hiroyuki Akagawa, Takakazu Kawamata
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10740
[Journal Article] Letter to the Editor. Influence of rare RNF213 variants other than p.R4810K on the clinical outcomes of moyamoya disease2018
- Author(s)
  Nomura Shunsuke、Kawashima Akitsugu、Akagawa Hiroyuki、Kawamata Takakazu
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 129 Issue: 2 Pages: 563-565
- DOI
  10.3171/2018.1.jns173211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10740
[Journal Article] Exome Sequencing Identified CCER2 as a Novel Candidate Gene for Moyamoya Disease.2017
- Author(s)
  Mukawa M, Nariai T, Onda H, Yoneyama T, Aihara Y, Hirota K, Kudo T, Sumita K, Maehara T, Kawamata T, Kasuya H, Akagawa H.
- Journal Title
  
  J Stroke Cerebrovasc Dis.
  
  Volume: 26 Issue: 1 Pages: 150-161
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.09.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26305031, KAKENHI-PROJECT-16K10740
[Journal Article] Association of rare nonsynonymous variants in PKD 1 and PKD2 with familial intracranial aneurysms in a Japanese population2016
- Author(s)
  Hirota K, Akagawa H, Onda H, Yoneyama T, Kawamata T, Kasuya H
- Journal Title
  
  J Stroke Cerbrovasc Dis
  
  Volume: 12 Issue: 12 Pages: 2900-2906
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.08.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10316
[Journal Article] Network-based gene expression analysis of vascular wall of juvenile Moyamoya disease.2015
- Author(s)
  Nobuya Okami, Yasuo Aihara, Hiroyuki Akagawa, Koji Yamaguchi, Akitsugu Kawashima, Toshiyuki Yamamoto, Yoshikazu Okada
- Journal Title
  
  Child's Nervous System
  
  Volume: 31 Issue: 3 Pages: 399-404
- DOI
  10.1007/s00381-014-2605-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670649
[Journal Article] Systematic validation of RNF213 coding variants in Japanese patients with Moyamoya disease2015
- Author(s)
  Yosuke Moteki, Hideaki Onda, Hidetoshi Kasuya, Taku Yoneyama, Yoshikazu Okada, Kengo Hirota, Maki Mukawa, Tadashi Nariai, Shohei Mitani, Hiroyuki Akagawa
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 4 Issue: 5 Pages: 1-10
- DOI
  10.1161/jaha.115.001862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670649, KAKENHI-PROJECT-26305031, KAKENHI-PROJECT-24390053
[Journal Article] Association of the Jun dimerization protein 2 gene with intracranial aneurysms in Japanese and Korean cohorts as compared to a Dutch cohort2010
- Author(s)
  Krischek B, Tajima A, Akagawa H, Narita A, Ruigrok Y, Rinkel G, Wijmenga C, Feigl GC, Kim CJ, Hori T, Tatagiba M, Kasuya H, Inoue I
- Journal Title
  
  Neuroscience
  
  Volume: 169(1) Pages: 339-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791359
[Journal Article] 脳動脈瘤の遺伝解析2008
- Author(s)
  恩田英明、米山琢、赤川浩之、糟谷英俊
- Journal Title
  
  BRAIN a nd NERVE 60巻11号
  
  Pages: 1245-1260
- NAID
  10024937396
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] 脳動脈瘤の遺伝解析2008
- Author(s)
  恩田英明、米山琢、赤川浩之糟谷英俊
- Journal Title
  
  BRAIN and NERVE 60巻11号
  
  Pages: 1245-1260
- NAID
  10024937396
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] Gene-expression in a canine basilar artery vasospasm model: a genome-wide network-based analysis.2008
- Author(s)
  Sasahara A, Kasuya H, Krischek B, Tajima A, Onda H, Sasaki T, Akagawa H, Hori T, Inoue I
- Journal Title
  
  Neurosurg Rev 31
  
  Pages: 283-290
- Data Source
  KAKENHI-PROJECT-19591705
[Journal Article] Network-based gene expression analysis of intracranial aneurysm tissue reveals role of antigen presenting cells2008
- Author(s)
  Krischek B, Kasuya H, Tajima A, Akagawa H, et.al.
- Journal Title
  
  Neuroscience Jul 17 ; 154(4)
  
  Pages: 1398-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptible gene to intracranial aneurysms.2007
- Author(s)
  Akagawa H, Narita A, Yamada H, Tajima A, Krischek B, Kasuya H, Hori T, Kubota M, Saeki N, Hata A, Mizutani T, Inoue I
- Journal Title
  
  Hum Genet 121
  
  Pages: 377-387
- Data Source
  KAKENHI-PROJECT-19591705
[Journal Article] Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms2007
- Author(s)
  Akagawa H, Narita A, Yamada H, Tajima A, Krischek B, Kasuya H, Hori T, Kubota M, Saeki N, Hata A, Mizutani T, Inoue I
- Journal Title
  
  Hum Genet 121(3-4)
  
  Pages: 377-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] Systematic screening of lysyl oxidase-like (LOXL) family genes demonst-rates that LOXL2 is a susGeptibility gene to intracranial aneurysms.2007
- Author(s)
  Akagawa H, Narita A, et. al.
- Journal Title
  
  Human Genetics 121(3-4)
  
  Pages: 377-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] 脳動脈瘤と遺伝子2007
- Author(s)
  米山琢、赤川浩之、恩田英明、糟谷英俊
- Journal Title
  
  東京女子醫科大學雑誌 77(5)
  
  Pages: 219-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791013
[Journal Article] Using endothelial nitric oxide synthase gene polymorphisms to identify intracranial aneurysms that are more prone to rupture in Japanese patients.2006
- Author(s)
  Krisheck B, Kasuya H, H Akagawa 他
- Journal Title
  
  J Neurosurg 105
  
  Pages: 717-722
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Is there any evidence for linkage on chromosome 17cen in affected Japanese sib-pairs with an intracranial aneurysm?2006
- Author(s)
  Krischek B, Narita A, Akagawa H, Kasuya H 他
- Journal Title
  
  J Hum Genet 51
  
  Pages: 491-494
- NAID
  10019168190
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.2006
- Author(s)
  Akagawa H, Tajima A, Sakamoto Y, 他
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 1722-1734
- Data Source
  KAKENHI-PROJECT-17790985
[Journal Article] Is there any evidence for linkage on chromosome 17cen in affected Japanese sib-pairs with an intracranial aneurysm?2006
- Author(s)
  Krischek B, Narita A, Akagawa H, Kasuya H, 他
- Journal Title
  
  J Hum Genet 51
  
  Pages: 491-494
- NAID
  10019168190
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Is there any evidence for linkage on chromosome 17cen in affected Japanese sib-pairs with an intracranial aneurysm?2006
- Author(s)
  Krischek B, Narita A, Akagawa H, Kasuya H, Tajima A, Onda H, Yoneyama T, Hori T, Inoue I
- Journal Title
  
  J Hum Genet 51
  
  Pages: 491-494
- NAID
  10019168190
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.2006
- Author(s)
  Akagawa H, Tajima A, Sakamoto Y, Krischek B, Yoneyama T, Kasuya H, Onda H, Hori T, Kubota M, Machida T, Saeki N, Hata A, Hashiguchi K, Kimura E, Kim CJ, Yang TK, Kimm K, Inoue I
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 1722-1734
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Using endothelial nitric oxide synthase gene polymorphisms to identify intracranial aneurysms that are more prone to rupture in Japanese patients.2006
- Author(s)
  Krisheck B, Kasuya H, H Akagawa, 他
- Journal Title
  
  J Neurosurg 105
  
  Pages: 717-722
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.2006
- Author(s)
  Akagawa H, Tajima A, Sakamoto Y, H Kasuya, 他
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 1722-1734
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Using endothelial nitric oxide synthase gene polymorphisms to identify intracranial aneurysms that are more prone to rupture in Japanese patients.2006
- Author(s)
  Krisheck B, Kasuya H, H Akagawa, Onda H, Hori T, Inoue I
- Journal Title
  
  J Neurosurg 105
  
  Pages: 717-722
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms.2006
- Author(s)
  Akagawa H, Tajima A, Sakamoto Y, Krischek B, Yoneyama T, Kasuya H 他
- Journal Title
  
  Hum Mol Genet 15
  
  Pages: 1722-1734
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Endothelial nitric oxide synthase T-786C single nucleotide polymorphism is not a factor influencing the aneurysm size.2005
- Author(s)
  Akagawa H, Kasuya H, Onda H, 他
- Journal Title
  
  J Neurosurg 102
  
  Pages: 68-71
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Endothelial nitric oxide synthase T-786C single nucleotide polymorphism is not a factor influencing the aneurysm size.2005
- Author(s)
  Akagawa H, Kasuya H, Onda H, Yoneyama T, Sasahara A, Kim CJ, Lee JC, Yang TK, Hori T, Inoue I
- Journal Title
  
  J Neurosurg 102
  
  Pages: 68-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591533
[Journal Article] Endothelial nitric oxide synthase T-786C single nucleotide polymorphism is not a factor influencing the aneurysm size.2005
- Author(s)
  Akagawa H, Kasuya H, et al.
- Journal Title
  
  J Neurosurg 102
  
  Pages: 68-71
- Data Source
  KAKENHI-PROJECT-17591533
[Presentation] 全エクソームシークエンシングで診断に至った日本人MODY1患者5家系についての検討2024
- Author(s)
  田中　慧、赤川浩之、岩﨑直子
- Organizer
  第67回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 遺伝子異常による糖尿病15症例に対するGLP1-RAの血糖コントロール改善効果2023
- Author(s)
  岩﨑直子, 田中慧, 赤川浩之, 大澤真里, 長谷美智代, 尾形真規子
- Organizer
  第66回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Next Generation Sequencing in Japanese patients with Maturity-Onset Diabetes of the Young.2023
- Author(s)
  Satoshi Tanaka,. Naoko Iwasaki, Kenko Azuma, Hiroyuki Akagawa, Shohei Mitani
- Organizer
  Human Genectics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] MODY5疑い症例のスクリーニングにより同定された15例のMODY5症例におけるgenotype-phenotypeの検討2022
- Author(s)
  岩崎直子, 田中　慧, 赤川浩之, 尾形真規子, 井出理沙, 馬場園哲也, 齋藤加代子
- Organizer
  第65回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] もやもや症候群の全エクソーム解析2022
- Author(s)
  中村彰一、赤川浩之、野村俊介、成相直、原祥子、Thamamongood Thiparpa、川俣貴一
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09537
[Presentation] 次世代シークエンサーを用いたMonogenic diabetesのスクリーニング2022
- Author(s)
  岩崎直子, 田中慧, 赤川浩之
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 日本人MODY1患者の全エクソームシーケンシング解析2022
- Author(s)
  田中慧, 赤川浩之, 岩崎直子
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 成人期に診断された新規バリアントによるMODY2の姉妹例2022
- Author(s)
  田中　慧、赤川浩之、馬場園哲也、岩崎直子
- Organizer
  第65回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] Genetic screening for monogenic diabetes using whole exome sequencing in a single hospital cohort in Japan2022
- Author(s)
  Tanaka Satoshi, Akagawa Hiroyuki, Ogata Makiko, Iwasaki Naoko
- Organizer
  58th European Association for the Study of Diabetes Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 全エクソームシークエンスによるMODY遺伝子のゲノム構造異常の解析2021
- Author(s)
  岩崎直子, 赤川浩之, 東剣虹
- Organizer
  日本人類遺伝学会　第66回大会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] 全エクソームシーケンシングによるMODY27症例の網羅的遺伝子解析2021
- Author(s)
  岩崎直子、赤川浩之、長谷美智代、尾形真規子、斎藤加代子
- Organizer
  第64回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-21K06281
[Presentation] RNF213 p.R4810K変異遺伝子変異と小児もやもや病の臨床像2021
- Author(s)
  原祥子 , 成相直 , 矢藤優一 , タンマモングッド・ティプアーパー , 赤川浩之 , 糟谷英俊 , 前原健寿
- Organizer
  第49回日本小児神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09537
[Presentation] もやもや病患者における甲状腺抗体とRNF213遺伝子型2020
- Author(s)
  Thamamongood Thiparpa, 赤川浩之, 原祥子, 前原健寿, 成相直
- Organizer
  第79回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09537
[Presentation] もやもや病・もやもや症候群の遺伝子解析2019
- Author(s)
  赤川浩之, 野村俊介, Boris Krischek, 武川麻紀, 前原健寿, 成相直, 糟谷英俊, 川俣貴一
- Organizer
  Stroke2019第44回日本脳卒中学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] Exome Sequencing Identified CCER2 as a Novel Candidate Gene for Moyamoya Disease.2018
- Author(s)
  Hiroyuki Akagawa
- Organizer
  5th International Moyamoya meeting (Seoul, Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] Exome sequencing identified CCER2 as a novel candidate gene for Moyamoya disease2018
- Author(s)
  Hiroyuki Akagawa
- Organizer
  5th International Moyamoya Meeting (IMM 2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] 次世代シーケンサーによる類もやもや病の遺伝子解析2018
- Author(s)
  野村俊介, 赤川浩之, 川島明次, 山口浩司, 石川達也, 武川麻紀, 成相直, 糟谷英俊, 川俣貴一
- Organizer
  第47回日本脳卒中の外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] もやもや病の病態と治療：感受性遺伝子解析の観点から2018
- Author(s)
  赤川浩之、野村俊介、Boris Krischek、武川麻紀、前原健寿、成相直、糟谷英俊、川俣貴一
- Organizer
  第77回日本脳神経外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] 次世代シーケンサーによるもやもや病の感受性遺伝子解析2017
- Author(s)
  野村俊介, 赤川浩之, 山口浩司, 石川達也, 川島明次, 武川麻紀, 成相直, 糟谷英俊, 川俣貴一
- Organizer
  日本脳神経外科学会第76回学術総会
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] Genetics of Moyamoya disease2017
- Author(s)
  Hiroyuki Akagawa
- Organizer
  5th International Neurosurgical Conference on MoyaMoya Disease（煙台市、中国）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10740
[Presentation] もやもや病の病態に迫る：新規感受性遺伝子の検索2016
- Author(s)
  赤川浩之、恩田英明、米山琢、藍原康雄、Boris Krischek、武川麻紀、成相直、前原健寿、川俣貴一、糟谷英俊
- Organizer
  第41回日本脳卒中学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26670649
[Presentation] もやもや病感受性遺伝子のアレル異質性と座位異質性2015
- Author(s)
  赤川浩之、恩田英明、米山琢、茂木陽介、広田健吾、Roder Constantin、Krischek Boris、武川麻紀、成相直、前原健寿、川俣貴一、糟谷英俊
- Organizer
  日本脳神経外科学会第74回学術総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26670649
[Presentation] 次世代シーケンサーによる家族性脳動脈瘤の多発性嚢胞腎遺伝子ターゲットリシーケンス2015
- Author(s)
  広田健吾、赤川浩之、恩田英明、糟谷英俊
- Organizer
  日本脳神経外科学会第74回学術総会
- Place of Presentation
  ロイトン札幌(北海道・　札幌市）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K10316
[Presentation] Systematic Validation of RNF213 Coding Variants in Japanese Patients With Moyamoya Disease2015
- Author(s)
  赤川浩之、恩田英明、米山琢、茂木陽介、武川麻紀、成相直、岡田芳和、糟谷英俊
- Organizer
  第16回日本分子脳神経外科学会
- Place of Presentation
  アクトシティー浜松コングレスセンター（静岡県浜松市）
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-26670649
[Presentation] R4859K陰性もやもや病家系における新たな原因変異の検索2013
- Author(s)
  茂木陽介、赤川浩之、恩田英明、糟谷英俊、岡田芳和
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-16
- Data Source
  KAKENHI-PROJECT-23592109
[Presentation] もやもや病の遺伝解析2013
- Author(s)
  恩田英明、赤川浩之、茂木陽介、成相直、岡田芳和、糟谷英俊
- Organizer
  第21回河田町脳神経外科懇話会
- Place of Presentation
  京王プラザホテル43階スターライト
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-23592109
[Presentation] もやもや病の遺伝解析2013
- Author(s)
  恩田英明、赤川浩之、茂木陽介、成相直、岡田芳和、糟谷英俊
- Organizer
  第21回河田町脳神経外科懇話会
- Place of Presentation
  京王ﾌﾟﾗｻﾞﾎﾃﾙ43階ｽﾀｰﾗｲﾄ
- Data Source
  KAKENHI-PROJECT-23592109
[Presentation] Confirmation of an association of TNFRSF13B sequence variants with intracranial aneurysms in Japanese patients2011
- Author(s)
  Hiroyuki Akagawa, Taku Yoneyama, Hideaki Onda, Boris Krischek, Tsutomu Nishizawa, Hidetoshi Kasuya
- Organizer
  2011 AANS 79th Annual Scientific Meeting
- Place of Presentation
  Colorado Convention Center, Denver, Colorado
- Data Source
  KAKENHI-PROJECT-22791359
[Presentation] Confirmation of an association of TNFRSF13B sequence variants with intracranial aneurysms in Japanese patients2011
- Author(s)
  Hiroyuki Akagawa
- Organizer
  2011 American Association of Neurological Surgeons (AANS) 79^<th> Annual Meeting
- Place of Presentation
  Colorado Convention Center, Denver, Colorado
- Data Source
  KAKENHI-PROJECT-22791359
[Presentation] 脳動脈瘤候補遺伝子のrare variantを用いた関連解析2010
- Author(s)
  赤川浩之
- Organizer
  第11回日本分子脳神経外科学会
- Place of Presentation
  艮陵会館記念ホール(仙台市)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22791359
[Presentation] 脳動脈瘤候補遺伝子のRare Variantを用いた関連解析2010
- Author(s)
  赤川浩之、米山琢、恩田英明、西澤勉、岡田芳和、糟谷英俊
- Organizer
  第11回日本分子脳神経外科学会
- Place of Presentation
  仙台
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22791359
[Presentation] 家族性脳動脈瘤患者におけるTNFRSF13B遺伝子の変異解析2008
- Author(s)
  赤川浩之、竹原弥生、米山琢、恩田英明、糟谷英俊、堀智勝
- Organizer
  第9回日本分子脳神経外科学会
- Place of Presentation
  京都
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19791013
[Presentation] Lysyl oxidase-like (LOXL) family遺伝子群と脳動脈瘤のSNPs関連解析2007
- Author(s)
  赤川浩之、成田暁、田嶋敦、米山琢、Boris Krische、恩田英明、糟谷英俊、堀智勝、井ノ上逸朗
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  東京
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19791013

1. KASUYA Hidetoshi (50169455)

# of Collaborated Projects: 8 results

# of Collaborated Products: 28 results
2. ONDA Hideaki (60185692)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
3. YONEYAMA Taku (90318105)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. NARIAI Tadashi (00228090)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. Nitta Masayuki (70588269)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 広田健吾 (10532690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 増井憲太 (60747682)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 都築俊介 (90746794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 岩崎直子 (70203370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. INOUE Tatsuya (70398808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MUKAWA Maki (90463918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. INOUE Ituro (00192500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SASAHARA atsushi (40287371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOSEKI Hirokazu (10766546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤田俊之 (40718095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 丸山隆志 (40301543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 安田崇之 (70725366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 青木友浩 (40633144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 齋藤太一 (40457247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 福井敦 (80746800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 郡山峻一 (10793979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 茂木陽介 (30649405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 新井直幸 (70868736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 永井礼子 (10622160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 岡本孝之 (70636349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小西崇夫 (80849117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 佐藤弘樹 (40531306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TAKAHASHI yuichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Muragaki Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 稲次基希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 井ノ上逸朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

akagawa hiroyuki 赤川 浩之

AKAGAWA Hiroyuki 赤川 浩之

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特発性頚部内頚動脈攣縮症の遺伝子改変モデルラットを用いた病態解明研究Principal Investigator

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Next-generation sequencing of moyamoya syndromePrincipal Investigator

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Identification of novel susceptibility genes associated with moyamoya disease without pathogenic variants in RNF213Principal Investigator

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Resequencing analysis of the 19q25.3 locus associated with Moyamoya disease in JapanPrincipal Investigator

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Next generation sequencing of susceptibility loci for intracranial aneurysms to identify disease-causal mutationsPrincipal Investigator

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akagawa hiroyuki 赤川浩之

AKAGAWA Hiroyuki 赤川浩之