IWAKI SOICHIRO 岩城壮一郎

… Alternative Names

IWAKI Soichiro 岩城壮一郎

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Researcher Number	60399962
Other IDs
Affiliation (Current)	2025: 岐阜医療科学大学, 薬学部, 准教授 2025: 名古屋市立大学, 医薬学総合研究院(薬学), 講師
Affiliation (based on the past Project Information) *help	2016: 名古屋市立大学, 大学院薬学研究科, 講師 2015: 名古屋市立大学, 薬学研究科, 講師 2012 – 2015: 名古屋市立大学, 薬学研究科(研究院), 講師 2012: 名古屋市立大学, 大学院・薬学研究科, 講師 2010 – 2011: 名古屋市立大学, 大学院・薬学研究科, 助教 … More 2009: Nagoya City University, 薬学研究科(研究院), 助教 2007: Nagoya City University, Pharmaceutical Sciences, Assistant 2006: 大学院薬学研究院, 博士研究員 Less
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Medical pharmacy / Functional biochemistry
Keywords	Principal Investigator miRNA / バイオマーカー / 動脈硬化 / 動脈硬化症 / エクソソーム / スフィンゴシン1-リン酸 / PAI-1 Except Principal Investigator 脂質 / 生理活性 / immunusupressant … More / mast cell / ceramide / C1P / Sphingosine 1-phosphate (S1P) / bioactive / biomolecule / sphingolipid / 血漿 / 生理活性脂質 / セミラド1-リン酸 / セミラド / スフィンゴ脂質 / 免疫抑制剤 / マスト細胞 / セラミド / セラミド1-リン酸 / スフィンゴシン1-リン酸 / 生体分子 / バイオマーカー / 分泌型miRNA / 糖尿病 / 褥瘡 / 皮膚潰瘍 / 高齢者 / HDL / ナノ粒子 / 動脈硬化症 / 内皮前駆細胞 / 臨床 / 薬学 Less

The development of novel biomarker for arteriosclerosis using circulating miRNAs.Principal Investigator
- Principal Investigator
  
  Iwaki Soihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Establishment and application of the new treatment method of evaluation method of pressure ulcers, diabetic skin ulcers by secreted miRNA
- Principal Investigator
  
  Fujii Satoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Asahikawa Medical College
  Nagoya City University
Evaluation of circulating miRNA in exosomes for novel biomarker of arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  IWAKI Soichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Development of pioneering therapy for early atherosclerosis using novel S1P donor
- Principal Investigator
  
  FUJII Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Exploration of novel biomarker for diagnosis of early stage of arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  IWAKI Soichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Biological functions of Sphingolipids and their relevance to pathological phenomena
- Principal Investigator
  
  YASUYUKI Igarashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hokkaido University

All 2016 2015 2014 2013 2012 2011 2010 2009 2007 2006 Other

All Journal Article Presentation

[Journal Article] Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.2016
- Author(s)
  Suzuki M, et al.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 126 Issue: 1 Pages: 254-265
- DOI
  10.1172/jci79775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-15K12527, KAKENHI-PUBLICLY-26110717, KAKENHI-PROJECT-26889060, KAKENHI-PROJECT-25460217, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25289299, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-25250017, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-16H04767
[Journal Article] Sphingosine 1-phosphate induced by hypoxia increases the expression of PAI-1 in HepG2 cells via HIF-1α2016
- Author(s)
  Akimasa Sanagawa, Soichiro Iwaki, Moyoko Asai, Daisuke Sakakibara, Hiroaki Norimoto, Burton E. Sobel, Satoshi Fujii
- Journal Title
  
  Mol Med Rep.
  
  Volume: 14 Issue: 2 Pages: 1841-1848
- DOI
  10.3892/mmr.2016.5451
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-16H00574
[Journal Article] Circulating Level of MicroRNA-126 may be a Potential Biomarker for Recovery from Smoking-Related Vascular Damage in Middle-Aged Habitual Smokers.2015
- Author(s)
  Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Soichiro Iwaki, Shiori Ito, Akimasa Sanagawa, Nobuyuki Ohte, Satoshi Fujii
- Journal Title
  
  IJC Heart & Vasculature
  
  Volume: 印刷中 Pages: 83-87
- DOI
  10.1016/j.ijcha.2015.02.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-24790559
[Journal Article] Increased Acid Ceramidase Expression depends on Upregulation of Androgen-dependent Deubiquitinases, USP2, in a Human Prostate Cancer Cell Line, LNCaP.2015
- Author(s)
  Naoki Mizutani, Minami Inoue, Yukari Omori, Hiromi Ito, Keiko Tamiya-Koizumi, Akira Takagi, Tetsuhito Kojima, Mitsuhiro Nakamura, Soichiro Iwaki, Masahiro Nakatochi, Motoshi Suzuki, Yoshinori Nozawa, Takashi Murate
- Journal Title
  
  J. Biochem.
  
  Volume: 印刷中 Issue: 4 Pages: 309-319
- DOI
  10.1093/jb/mvv039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460203, KAKENHI-PROJECT-26460674, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-26290051
[Journal Article] Circulating level of microRNA-126 may be a potential biomarker for recovery from smoking-related vascular damage in middle-aged habitual smokers.2015
- Author(s)
  Sugiura T, Dohi Y, Yamashita S, Iwaki S, Ito S, Sanagawa A, Ohte N, Fujii S.
- Journal Title
  
  Int J Cardiol: Heart and Vasculature
  
  Volume: 7 Pages: 83-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460217
[Journal Article] TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis.2014
- Author(s)
  Ito S, Iwaki S, Kondo R, Satoh M, Iwabuchi K, Ohkawa R, Mishima Y, Yatomi Y, Furumoto T, Tsutsui H, Fujii S.
- Journal Title
  
  Coronary Artery Disease
  
  Volume: 25 Pages: 311-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460217
[Journal Article] TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: Ramifications of correlation between plasma S1P levels and metabolic syndrome2014
- Author(s)
  Shiori Ito
- Journal Title
  
  Coron. Artery Dis.
  
  Volume: 25 Issue: 4 Pages: 311-320
- DOI
  10.1097/mca.0000000000000082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790164, KAKENHI-PROJECT-25460502, KAKENHI-PROJECT-25870708
[Journal Article] スフィンゴシン1-リン酸のヒト皮膚線維芽細胞におけるコラーゲン産生に及ぼす影響2013
- Author(s)
  岩城壮一郎
- Journal Title
  
  日本褥瘡学会誌
  
  Volume: 15 Pages: 8-14
- NAID
  40019799975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790164
[Journal Article] スフィンゴシン1-リン酸のヒト皮膚線維芽細胞におけるコラーゲン産生に及ぼす影響2013
- Author(s)
  岩城壮一郎、松井恵利華、藤井聡
- Journal Title
  
  日本褥瘡学会誌
  
  Volume: 15巻 Pages: 8-14
- NAID
  40019799975
- URL
  http://mol.medicalonline.jp/library/journal/abstract?GoodsID=du9jokso/2013/001501/002&name=0008-0014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790164
[Journal Article] Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.2013
- Author(s)
  Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S,Fujii S,Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  Biochimica et Biophysica Acta -Molecular Cell Research
  
  Volume: 1833 Issue: 5 Pages: 1006-16
- DOI
  10.1016/j.bbamcr.2013.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-24790164
[Journal Article] Increased Plasma Sphingosine-1-Phosphate in Obese Subjects and Its Capacity to Increase Expression of Plasminogen Activator Inhibitor-1 in Adipocytes2013
- Author(s)
  Shiori Ito, Soichiro Iwaki, Keiko Koike, Yuichiro Yuda, Ayako Nagasaki, Ryunosuke Ohkawa, Yutaka Yatomi, Tomoo Furumoto, Hiroyuki Tsutsui, Burton E Sobel, Satoshi Fujii
- Journal Title
  
  Coron. Artery Dis
  
  Volume: 24 Issue: 8 Pages: 642-650
- DOI
  10.1097/mca.0000000000000033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790164, KAKENHI-PROJECT-25460217, KAKENHI-PROJECT-26460203
[Journal Article] Role of down-regulated neutral ceramidase during all-trans retinoic acid induced neuronal differentiation in SH-SY5Y neuroblastoma cells2012
- Author(s)
  Kouji Tanaka
- Journal Title
  
  J.Biochem.
  
  Volume: (印刷中) Issue: 6 Pages: 611-620
- DOI
  10.1093/jb/mvs033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139, KAKENHI-PUBLICLY-23107712, KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-23659664, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-24790164
[Journal Article] Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells. Biochimica et Biophysica Acta2012
- Author(s)
  Iwaki S
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1819 Pages: 1132-1141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139
[Journal Article] Expression of circulating microRNA-126 in patients with coronary artery disease: correlation with LDL cholesterol.2012
- Author(s)
  Sun X, Zhang M, Sanagawa A, Mori C, Ito S, Iwaki S, Satoh H, Fujii S.
- Journal Title
  
  Thromb J
  
  Volume: 10(1) Issue: 1 Pages: 16-16
- DOI
  10.1186/1477-9560-10-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-24790164
[Journal Article] Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells.2012
- Author(s)
  Iwaki S, Yamamura S, Asai M, Sobel BE, Fujii S.
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1819 Pages: 1132-1141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139
[Journal Article] Role of down-regulated neutral ceramidase during all-trans retinoic acid induced neuronal differentiation in SH-SY5Y neuroblastoma cells.2012
- Author(s)
  Kouji Tanaka, Keiko Tamiya-Koizumi, Kazumi Hagiwara, Hiromi Ito, Akira Takagi, Tetsuhito Kojima, Motoshi Suzuki, Soichiro Iwaki, Satoshi Fujii, Mitsuhiro Nakamura, Yoshiko Banno, Reiji Kannagi, Tatsuya Tsurumi, Mamoru Kyogashima, Takashi Murate.
- Journal Title
  
  J. Biochem.
  
  Volume: (in press)
- NAID
  10031166103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis2012
- Author(s)
  Tomonori Sugiura
- Journal Title
  
  Coron.Artery Dis.
  
  Volume: (印刷中) Issue: 4 Pages: 234-238
- DOI
  10.1097/mca.0b013e328351ab0a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139, KAKENHI-PROJECT-24790164
[Journal Article] Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells2012
- Author(s)
  Soichiro Iwaki, Shuhei Yamamura, Moyoko Asai, Burton E. Sobel, Satoshi Fujii
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1819 Issue: 11-12 Pages: 1132-1141
- DOI
  10.1016/j.bbagrm.2012.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790164
[Journal Article] Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis.2012
- Author(s)
  Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Nobuyuki Ohte, Shiori Ito, Soichiro Iwaki, Yuji Hirowatari, Ryunosuke Ohkawa, Yuko Mishima, Yutaka Yatomi, Genjiro Kimura, Satoshi Fujii.
- Journal Title
  
  Coron. Artery Dis.
  
  Volume: 23 Pages: 234-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] Modulators of induction of plasminogen activator inhibitor type-1 in HepG2 cells by transforming growth factor-β2011
- Author(s)
  Naomi Nakayama
- Journal Title
  
  Coron.Artery Dis.
  
  Volume: 22 Issue: 7 Pages: 468-478
- DOI
  10.1097/mca.0b013e32834a3817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139
[Journal Article] Modulators of induction of plasminogen activator inhibitor type-1 in HepG2 cells by transforming growth factor-β2011
- Author(s)
  Naomi Nakayama, Tomomi Nakamura, Hiromi Okada, Soichiro Iwaki, Burton E. Sobel, Satoshi Fujii
- Journal Title
  
  Coron. Artery Dis
  
  Volume: 22 Pages: 468-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by cAMP in HepG2 liver cells2011
- Author(s)
  Takefumi Asakura
- Journal Title
  
  J.Biochem.
  
  Volume: 150 Issue: 6 Pages: 687-694
- DOI
  10.1093/jb/mvr110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156, KAKENHI-PROJECT-22590139
[Journal Article] Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by cAMP in HepG2 liver cells2011
- Author(s)
  Takefumi Asakura, Soichiro Iwaki, Hiromi Okada, Burton E. Sobel, Satoshi Fujii
- Journal Title
  
  J. Biochem.
  
  Volume: 150 Pages: 687-694
- NAID
  10030589369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] Increased expression of PAI-1 in HepG2 cells induced by insulin mediated by the 3'-untranslated region of the PAI-1 gene and its pharmacologic implications.2010
- Author(s)
  Miyagawa R, Asakura T, Nakamura T, Okada H, Iwaki S, Sobel B, Fujii S.2010
- Journal Title
  
  Coronary Artery Disease
  
  Volume: 21 Pages: 144-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139
[Journal Article] Increased expression of plasminogen activator inhibitor type-1 (PAI-1) in HEPG2 cells induced by insulin mediated by the 3'-untranslated region of the PAI-1 gene and its pharmacologic implications.2010
- Author(s)
  Miyagawa R, Asakura T, Nakamura T, Okada H, Iwaki S, Sobel, B, Fujii S.
- Journal Title
  
  Cor Art Dis
  
  Volume: 21 Issue: 3 Pages: 144-50
- DOI
  10.1097/mca.0b013e328335790e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590139
[Journal Article] Increased expression of plasminogen activator inhibitor type-1(PAI-1) in HepG2 cells induced by insulin mediated by the 3'-untranslated region of the PAI-1 gene and its pharmacologic implications2010
- Author(s)
  Ryu Miyagawa, Takefumi Asakura, Tomomi Nakamura, Hiromi Okada, Soichiro Iwaki, Burton E. Sobel, Satoshi Fujii
- Journal Title
  
  Coron. Artery Dis.
  
  Volume: 21 Pages: 144-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] HepG2細胞におけるインスリンと酸化ストレスのPAI-1産生に対する影響の解析:メタボリックシンドロームの易血栓性の病態解明を指向して2010
- Author(s)
  宮川隆, 朝倉健文, 中村友美, 佐藤由樹, 岡田浩美, 岩城壮一郎, 藤井聡
- Journal Title
  
  心臓
  
  Volume: 42 Pages: 1153-1158
- NAID
  130002146949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790156
[Journal Article] Regulation of the transport and protein levels of the inositol phosphoryl ceramide mannosyltransferases Csg1 and Csh1 by the Ca2+-binding protein Csg2.2007
- Author(s)
  Uemura S, Kihara A, Iwaki S, Inokuchi JI, Igarashi Y.
- Journal Title
  
  J Biol Chem. 23;282(12)
  
  Pages: 8613-8621
- NAID
  120000969952
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Intracellular trafficking pathway of yeast long-chain base kinase Lcb4, from its sythesis to its degradation.2007
- Author(s)
  Iwaki S, Sano T, Takagi T, Osumi M, Kihara A, and Igarashi Y.
- Journal Title
  
  J. Biol. Chem 282(39)
  
  Pages: 28485-28492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Intracellular trafficking pathway of yeast long-chain base kinase Lcb4, from its sythesis to its degradation.2007
- Author(s)
  Iwaki S, Sano T, Takagi T, Osumi M, Kihara A, and Igarashi Y
- Journal Title
  
  J. Biol. Chem. vol.282 no.39
  
  Pages: 28485-28492
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Regulation of the transport and protein levels of the inositol phosphorylceramide mannosyltransferases Csgl and Cshl by the Ca2+-binding protein Csg2.2007
- Author(s)
  Uemura S, Kihara A, Iwaki S, Inokuchi JI, Igarashi Y.
- Journal Title
  
  J Biol Chem 282(12)
  
  Pages: 8613-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Regulation of the transport and protein levels of the inositol phosphoryl ceramide mannosyltransferases Csg1 and Csh1 by the Ca2+-binding protein Csg22007
- Author(s)
  Uemura S, Kihara A, Iwaki S, Inokuchi JI, Igarashi Y.
- Journal Title
  
  J Biol Chem. 23;282(12)
  
  Pages: 8613-8621
- NAID
  120000969952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Presentation] The role of the HIF-1α/HuR pathway in increased expression of PAI-1 induced by sphingosine 1-phosphate in HepG2 cells rendered hypoxic2016
- Author(s)
  Satoshi Fujii, Akimasa Sanagawa, Soichiro Iwaki, Moyoko Asai, Daisuke Sakakibara, Hiroaki Norimoto
- Organizer
  XXlllrd International Congress on Fibrinolysis & Proteolysis and XVlth International Workshop on Molecular and Cellular Biology of Plasminogen Activation
- Place of Presentation
  静岡市
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] 低酸素環境が血管内皮細胞由来miRNAと血管内皮機能に与える影響の解析2015
- Author(s)
  藤井聡, 小笠原美沙, 岩城壮一郎
- Organizer
  第37回日本血栓止血学会学術集会
- Place of Presentation
  甲府市総合市民会館
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] Hypoxia Induces Dysregulation of miR-126 and Affects VEGF and MMP-9 Expression in Endothelial Cells.2015
- Author(s)
  Satoshi Fujii, Misa Ogasawara, Soichiro Iwaki.
- Organizer
  2015 Congress of International Society on Thrombosis and Haemostasis.
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460217
[Presentation] スフィンゴ脂質が線溶系に与える影響の分子機構2014
- Author(s)
  岩城壮一郎
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] Blood Pressure Reduction and Increase of Circulating MicroRNA-126 Indicate Improvement of Vascular Endothelial Damage After Smoking Cessation Intervention in Middle-Aged Habitual Smokers2014
- Author(s)
  Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Akimasa Sanagawa, Soichiro Iwaki, Nobuyuki Ohte, Satoshi Fujii
- Organizer
  American Heart Association's 2014 Scientific Sessions and Resuscitation Science Symposium
- Place of Presentation
  シカゴ、アメリカ
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] スフィンゴシン1 リン酸/アポリポタンパクA1 含有金ナノ粒子による炎症性動脈硬化に対する新規ドラッグデリバリーシステムの開発2014
- Author(s)
  田上辰秋、高橋朋弘、岩城壮一郎、藤井聡、尾関哲也
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋市立大学
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] 転写因子CREBによるSphingosine kinase 2発現調節機序2014
- Author(s)
  水谷直貴、大森由佳里、小泉恵子、鈴木元、高木明、小嶋哲人、岩城壮一郎、藤井聡、中村光浩、野澤義則、村手隆
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] NKTハイブリドーマにおけるGLP-1によるS1Pを介したTNF-α発現制御機構2014
- Author(s)
  長谷川諒、伊藤史織、岩城壮一郎、岩渕和也、佐藤雅、藤井聡
- Organizer
  第36回日本血栓止血学会学術集会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] スフィンゴ脂質が線溶系に与える影響の分子機構2014
- Author(s)
  岩城壮一郎
- Organizer
  第15回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  名古屋市立大学
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460203
[Presentation] NKT細胞ハイブリドーマにおけるS1P受容体を介したTNF-α発現調節機構および遊走制御の解析2013
- Author(s)
  伊藤史織,岩城壮一郎,岩渕和也,藤井聡
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] The Expression of Plasminogen Activator Inhibitor Type-1 Is Post-transcriptionally Regulated By Sphingosine-1-phosphate And SERPINE1 mRNA binding protein.2013
- Author(s)
  Yamamura S, Iwaki S, Sanagawa A, Fujii S.
- Organizer
  The XXIVth Congress of the International Society on Thrombosis and Haemostasis.
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-25460217
[Presentation] 低酸素環境においてスフィンゴ脂質が線溶系に与える分子機構の解析2013
- Author(s)
  藤井聡、真川明将、岩城壮一郎、浅井萌子、榊原大輔、山村周平
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] S1PはPAI-1の発現を調節することで血液線溶系を制御する2013
- Author(s)
  岩城壮一郎、真川明将、吉川優、浅井萌子、榊原大輔、山村周平、藤井聡
- Organizer
  第14回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  日本薬学会長井記念ホール
- Year and Date
  2013-06-01
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] 炎症誘導モデルマウスに対する人工HDL金ナノ粒子製剤の抗炎症効果2013
- Author(s)
  高橋朋弘、田上辰秋、岩城壮一郎、藤井聡、尾関哲也
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] 低酸素環境においてスフィンゴ脂質が線溶系に与える分子機構の解析2013
- Author(s)
  藤井　聡、真川　明将、岩城　壮一郎、浅井　萌子、榊原　大輔、山村　周平
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-25460217
[Presentation] S1PはPAI-1の発現を調節することで血液線溶系を制御する2013
- Author(s)
  岩城壮一郎
- Organizer
  第14回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] S1Pが血液線溶系に与える影響の解明2013
- Author(s)
  真川明将, 岩城壮一郎, 浅井萌子, 榊原大輔, 山村周平, 藤井聡
- Organizer
  日本薬学会第132年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] HIF-1α/HuR Pathway Regulates the Increased Expression of PAI-1 Induced by Sphingosine 1-phosphate in HepG2 Cells Rendered Hypoxic: A Novel Linkage between Thrombosis and Hypoxia.2013
- Author(s)
  Sanagawa A, Iwaki S, Asai M, Sakakibara D, Norimoto H, Fujii S.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Dallas
- Data Source
  KAKENHI-PROJECT-25460217
[Presentation] Smoking-Induced Vascular Damage is Associated With Decreased Circulating MicroRNA-126 and Pesistent Elevation of Plasma Serotonin.2013
- Author(s)
  Sugiura T, Dohi Y, Yamashita S, Ohte N, Hirowatari Y, Ito S, Iwaki S, Fujii S.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Dallas
- Data Source
  KAKENHI-PROJECT-25460217
[Presentation] 善玉コレステロール(HDL)様ナノ粒子の創製とその物性評価2013
- Author(s)
  高橋朋弘、田上辰秋、岩城壮一郎、藤井聡、尾関哲也
- Organizer
  第22回DDSカンファランス
- Place of Presentation
  静岡
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] HepG2細胞におけるS1PによるPAI-1転写後調節機構の解析2012
- Author(s)
  山村周平, 岩城壮一郎, 真川明将, 朝倉健文, 藤井聡
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] Functional Engineered Nano-sized Particles and Their Pharmaceutical Applications2012
- Author(s)
  Tomohiro Takahashi, Tatsuaki Tagami, Satoshi Fujii, Soichiro Iwaki, Ryohei Ito, Hiroshi Yanai, Tetsuya Ozeki
- Organizer
  10th France - Japan DDS Symposium
- Place of Presentation
  Bordeaux, France
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] Circulating MicroRNA-126 as a Potential Biomarker for Recovery from Smoking-Related Endothelial Damage.2012
- Author(s)
  Sugiura T, Dohi Y, Yamashita S, Ohte N, Sanagawa A, Ito S, Iwaki S, Fujii S, Ohkawa R, Yatomi Y, Kimura G.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2012-11-07
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] S1P/ApoA1 搭載金ナノ粒子による血管内皮細胞に対する抗炎症効果の検討2012
- Author(s)
  高橋朋弘、田上辰秋、岩城壮一郎、藤井聡、尾関哲也
- Organizer
  第28回日本 DDS学会年会
- Place of Presentation
  札幌
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] 高血圧症および脂質異常症患者における血中スフィンゴシン1-リン酸濃度の解析2012
- Author(s)
  伊藤史織、岩城壮一郎、大川龍之介、矢冨裕、古本智夫、筒井裕之、藤井聡
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  ウェスティンナゴヤキャッスル
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] A novel HDL-like gold nanoparticles formulation with anti-inflammatory effect on vascular endothelial cells.2012
- Author(s)
  Tomohiro Takahashi, Tatsuaki Tagami, Soichiro Iwaki, Satoshi Fujii, Tetsuya Ozeki.
- Organizer
  AAPS Annual Meeting and Exposition
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] Increased plasma sphyingosine-1-phosphate (S1P) and its capacity to increase expression of PAI-1 in adipocytes and obese subjects.2012
- Author(s)
  Fujii S, Nagasaki A, Ito S, Iwaki S, Sobel B, Ohkawa R, Mishima Y, Yatomi Y, Furumoto T.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2012-11-06
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] 低酸素下のHepG2細胞におけるS1Pを介したPAI-1発現制御機構の解明2012
- Author(s)
  真川明将、岩城壮一郎、浅井萌子、榊原大輔、乗本裕明、長崎彩子、山村周平、藤井聡
- Organizer
  第85回日本生化学大会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] 金ナノ粒子を核とした人工 HDL ナノ粒子の調製と物性評価2012
- Author(s)
  高橋朋弘、田上辰秋、岩城壮一郎、藤井聡、尾関哲也
- Organizer
  日本薬剤学会第27回年会
- Place of Presentation
  神戸
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] The effects of sphingosine-1-phosphate on collagen expression in human skin fibroblasts2012
- Author(s)
  Satoshi Fujii, Shiori Ito, Yuichiro Yuda, Erika Matsui, Soichiro Iwaki
- Organizer
  第4回世界創傷治癒学会連合会議
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] マイクロRNA-126とLDLコレステロールの関係 : 冠動脈疾患での影響2012
- Author(s)
  真川明将、Xiao Sun、Zhang Man、森智恵子、伊藤史織、岩城壮一郎、藤井聡
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  ウェスティンナゴヤキャッスル
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] マイクロRNA : 血管障害を早期に検出可能とする新しいモダリティー2012
- Author(s)
  藤井聡、真川明将、伊藤史織、岩城壮一郎、森智恵子、Zhang Man、杉浦知範、土肥靖明、山下純世、Xiao Sun、木村玄次郎
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  ウェスティンナゴヤキャッスル
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24790164
[Presentation] ABC transporters can mediate extracellular release of S1P in adipocytes under hypoxia: implications for atherothrombosis in obesity.2012
- Author(s)
  Ayako Nagasaki, Yuichiro Yuda, Keiko Koike, Soichiro Iwaki, Satoshi Fujii
- Organizer
  7th Congres of the Asian-Pacific Society on Thrombosis and Hemostasis.
- Place of Presentation
  Melbourne, Australia.
- Year and Date
  2012-10-29
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] HepG2細胞におけるcAMPによるPAI-1転写後調節機構の解明2011
- Author(s)
  朝倉健文, 山村周平, 乘本裕明, 岡田浩美, 岩城壮一郎, 藤井聡
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] Statin-Induced Improvement of Human Endothelial Function is Mediated by Sphingosine 1-Phosphate.2011
- Author(s)
  Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Nobuyuki Ohte, Shiori Ito, Chieko Mori, Soichiro Iwaki, Yuji Hirowatari, Ryunosuke Ohkawa, Yuko Mishima, Yutaka Yatomi, Genjiro Kimura, Satoshi Fujii.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] S1PによるPAI-1発現調節機構に関する3'-UTR機能の解析2011
- Author(s)
  山村周平, 真川明将, 朝倉健文, 岩城壮一郎, 藤井聡
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] Sphingosine-1-phosphate increases hypoxia-induced up-regulation of plasminogen activator inhibitor-12010
- Author(s)
  Soichiro Iwaki
- Organizer
  第27回内藤コンファレンス生体膜ダイナミクスと脂質生物学[I]
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(北海道)
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] Hypoxia Enhances S1P Release From Adipocytes and Provokes S1P-mediated Insulin Resistance by Inducing TNF-α Expression in Adipose NKT Cells.2010
- Author(s)
  Fujii S, Ito S, Koike K, Iwaki S, Iwabuchi K, Ohkawa R, Mishima Y, Yatomi Y, Furumoto T.
- Organizer
  Scientific Session of the American Heart Association.
- Place of Presentation
  Chicago, USA
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22590139
[Presentation] 低酸素とスフィンゴ脂質は脂肪細胞PAI-1発現上昇を通じて肥満者の線溶不全に関与する2010
- Author(s)
  小池慶子、大垣恵理華、岩城壮一郎、大川龍之介、矢冨裕、藤井聡
- Organizer
  第8回血液・血栓オルビス
- Place of Presentation
  東京ドームホテル
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] Sphingosine-1-phosphate increases hypoxia-induced up-regulation of plasminogen activator inhibitor-12010
- Author(s)
  Soichiro Iwaki, Moyoko Asai, Daisuke Sakakibara, Satoshi Fujii
- Organizer
  第27回内藤コンファレンス生体膜ダイナミクスと脂質生物学[I]
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] HepG2細胞におけるPAI-1発現機構の解析:インスリン、cAMP、シロスタゾールの影響2009
- Author(s)
  朝倉健文、岡田浩美、岩城壮一郎、藤井聡
- Organizer
  第19回日本病院薬剤師会東海ブロック学術大会・平成21年度日本薬学会東海支部例会
- Place of Presentation
  四日市市文化会館
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] スフィンゴシン1-リン酸は低酸素下におけるHIF-1αを介したPAI-1発現を増加させる2009
- Author(s)
  浅井萌子、榊原大輔、岩城壮一郎、藤井聡
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21790156
[Presentation] 出芽酵母におけるスフィンゴ糖脂質合成の調節機構2007
- Author(s)
  上村聡志, 木原章雄, 岩城壮一郎、井ノ口仁一、五十嵐靖之
- Organizer
  第49回日本脂質生化学会
- Place of Presentation
  北海道大学(札幌)、JCBL49:103-106
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Presentation] 酵母スフィンゴイド塩基キナーゼLcb4pにおいて見られる細胞膜-ER間新規輸送機構2006
- Author(s)
  岩城壮一郎、佐野孝光、高木智子、大隅正子、木原章雄、五十嵐靖之
- Organizer
  第48回日本脂質生化学会
- Place of Presentation
  日本科学未来館(東京)JCBL48:271-274
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Presentation] Blood Pressure Reduction and Increase of Circulating MicroRNA-126 Indicate Improvement of Vascular Endothelial Damage after Smoking Cessation Intervention in Middle-aged Habitual Smokers.
- Author(s)
  Sugiura T, Dohi Y, Yamashita S, Iwaki S, Sanagawa A, Ogasawara M, Fujii S, Ohte N.
- Organizer
  87th American Heart Association Scientific Session,
- Place of Presentation
  Chicago
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460217

1. FUJII Satoshi (90291228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
2. OZEKI Tetsuya (60277259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. DOHI Yasuaki (40305529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SUGIURA Tomonori (60535235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ISOGAI Zenzou (20285208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YASUYUKI Igarashi (70091965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. KIHARA Akio (50333620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. MITSUTAKE Susumu (10344475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MIZUTANI Yukiko (30396296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IWAKI SOICHIRO 岩城 壮一郎

IWAKI Soichiro 岩城 壮一郎

Research Projects

Research Products

Co-Researchers

The development of novel biomarker for arteriosclerosis using circulating miRNAs.Principal Investigator

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Establishment and application of the new treatment method of evaluation method of pressure ulcers, diabetic skin ulcers by secreted miRNA

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Evaluation of circulating miRNA in exosomes for novel biomarker of arteriosclerosisPrincipal Investigator

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Development of pioneering therapy for early atherosclerosis using novel S1P donor

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Exploration of novel biomarker for diagnosis of early stage of arteriosclerosisPrincipal Investigator

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Biological functions of Sphingolipids and their relevance to pathological phenomena

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[Journal Article] Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.2016

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DOI

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[Journal Article] Sphingosine 1-phosphate induced by hypoxia increases the expression of PAI-1 in HepG2 cells via HIF-1α2016

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[Journal Article] Circulating Level of MicroRNA-126 may be a Potential Biomarker for Recovery from Smoking-Related Vascular Damage in Middle-Aged Habitual Smokers.2015

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DOI

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[Journal Article] Increased Acid Ceramidase Expression depends on Upregulation of Androgen-dependent Deubiquitinases, USP2, in a Human Prostate Cancer Cell Line, LNCaP.2015

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[Journal Article] Circulating level of microRNA-126 may be a potential biomarker for recovery from smoking-related vascular damage in middle-aged habitual smokers.2015

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[Journal Article] TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis.2014

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[Journal Article] TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: Ramifications of correlation between plasma S1P levels and metabolic syndrome2014

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[Journal Article] スフィンゴシン1-リン酸のヒト皮膚線維芽細胞におけるコラーゲン産生に及ぼす影響2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] スフィンゴシン1-リン酸のヒト皮膚線維芽細胞におけるコラーゲン産生に及ぼす影響2013

IWAKI SOICHIRO 岩城壮一郎

IWAKI Soichiro 岩城壮一郎