FUKUI Toshiro 福井寿朗

… Alternative Names

福井寿朗フクイトシロウ

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Researcher Number	60402905
Other IDs	https://orcid.org/0000-0003-1131-4067
Affiliation (Current)	2025: 関西医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 関西医科大学, 医学部, 准教授 2012 – 2018: 関西医科大学, 医学部, 講師 2008 – 2011: Kansai Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 大腸癌 / 癌幹細胞 / 腫瘍幹細胞 / Smad蛋白 / 組織幹細胞 / マウスモデル / 消化管上皮幹細胞 / 発生・分化 / シグナル伝達 / 細菌 … More / 癌 / 臨床応用 / 進展機構 / 発癌 / 消化管癌 / 進展メカニズム / 炎症生発癌 / 癌の進展 / 癌の発生 / 疾患モデルマウス / ヒト食道癌 / ヒト大腸癌 / 転移 / 脈管侵襲 / 深部浸潤 / 腫瘍化 / 大腸腫瘍モデルマウス / 大腸炎 / 大腸 / 小腸 / 食道 / 幹細胞 / pSmad2/3L-Thr / pSmad3L-Ser / モデルマウス / 大腸炎関連大腸癌 / リン酸化 / Smad / 癌化 / 粘膜再生 / 上皮幹細胞 / 腫瘍 / 消化管粘膜再生 / 上部消化管学(食道、胃、十二指腸) / 免疫学 Less

Analyses and clinical applications of carcinogenic and progression mechanisms of gastrointestinal cancers focusing on pSmad2/3L-Thr expressionPrincipal Investigator
- Principal Investigator
  
  福井寿朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kansai Medical University
Analysis of cancer stem cells and appearance, development and progression of cancer lesions focusing on phosphorylation of the linker region of Smad2/3Principal Investigator
- Principal Investigator
  
  FUKUI Toshiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Analysis of the epithelial stem cell and the regenerative and carcinogenic mechanisms of digestive tract from the point of view of pSmad2/3L-ThrPrincipal Investigator
- Principal Investigator
  
  FUKUI Toshiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
Identification of a biomarker of the epithelial stem cell and analysis of the regenerative and carcinogenic mechanisms of digestive tractPrincipal Investigator
- Principal Investigator
  
  FUKUI Toshiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
The analysis of relationships of lymphocyte differentiation, gastric mucosal immune response, and carcinogenic mechanism to signaling cascade of TGF-β.Principal Investigator
- Principal Investigator
  
  FUKUI Toshiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University

All 2023 2022 2017 2016 2015 2014 2013 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 見て診て学ぶ膵腫瘍の画像診断2009
- Author(s)
  岡崎和一、内田一茂、福井寿朗
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] A Short-Term Model of Colitis-Associated Colorectal Cancer That Suggests Initial Tumor Development and the Characteristics of Cancer Stem Cells2023
- Author(s)
  Matsumoto Yasushi、Fukui Toshiro、Horitani Shunsuke、Tanimura Yuji、Suzuki Ryo、Tomiyama Takashi、Honzawa Yusuke、Tahara Tomomitsu、Okazaki Kazuichi、Naganuma Makoto
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 14 Pages: 11697-11697
- DOI
  10.3390/ijms241411697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08020, KAKENHI-PROJECT-22K08055
[Journal Article] Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia2022
- Author(s)
  Uragami Tomio、Ando Yugo、Aoi Mamiko、Fukui Toshiro、Matsumoto Yasushi、Horitani Shunsuke、Tomiyama Takashi、Okazaki Kazuichi、Tsuneyama Koichi、Tanaka Hajime、Naganuma Makoto
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: - Issue: 5 Pages: 1885-1893
- DOI
  10.1007/s10620-022-07774-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08020
[Journal Article] Carcinogenic and stem cell-like phenotypes of Smad2/3 linker phosphorylation in a mouse model of colitis-associated colorectal cancer2017
- Author(s)
  Suzuki Ryo、Fukui Toshiro、Okazaki Kazuichi
- Journal Title
  
  The Journal of Kansai Medical University
  
  Volume: 68 Issue: 0 Pages: 17-22
- DOI
  10.5361/jkmu.68.17
- NAID
  130006218932
- ISSN
  0022-8400, 2185-3851
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-16K09330
[Journal Article] Phosphorylation of Smad2/3 at Specific Linker Threonine Indicates Slow-Cycling Intestinal Stem-Like Cells Before Reentry to Cell Cycle2015
- Author(s)
  Kishimoto M, Fukui T, Suzuki R, Takahashi Y, Sumimoto K, Okazaki T, Sakao M, Sakaguchi Y, Yoshida K, Uchida K, Nishio A, Matsuzaki K, Okazaki K
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 60 Issue: 2 Pages: 362-374
- DOI
  10.1007/s10620-014-3348-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591021, KAKENHI-PROJECT-25460938
[Journal Article] Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer2015
- Author(s)
  Ryo Suzuki
- Journal Title
  
  Journal of Crohn’s and Colitis
  
  Volume: 9 Issue: 7 Pages: 565-574
- DOI
  10.1093/ecco-jcc/jjv073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09053, KAKENHI-PROJECT-25460938
[Journal Article] Phosphorylation of Smad2/3 at the specific linker threonine residue indicates slow-cycling esophageal stem-like cells before re-entry to the cell cycle2014
- Author(s)
  Takahashi Y, Fukui T, Kishimoto M, Suzuki R, Mitsuyama T, Sumimoto K, Okazaki T, Sakao M, Sakaguchi Y, Yoshida K, Uchida K, Nishio A, Matsuzaki K, Okazaki K
- Journal Title
  
  Diseases of the Esophagus
  
  Volume: - Issue: 2 Pages: 107-115
- DOI
  10.1111/dote.12277
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591021, KAKENHI-PROJECT-25460938, KAKENHI-PROJECT-15K09053
[Journal Article] The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach ; particularly increasing in mucosae of Helicobacter-associated gastritis2011
- Author(s)
  Toshiro Fukui
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 46 Issue: 4 Pages: 456-168
- DOI
  10.1007/s00535-010-0364-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590878, KAKENHI-PROJECT-21790689, KAKENHI-PROJECT-22790676, KAKENHI-PROJECT-22390153
[Journal Article] The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach ; particularly increasing in mucosae of Helicobacter-associated gastritis.2011
- Author(s)
  Toshiro Fukui
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: (in press)
- NAID
  10029028438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790676
[Journal Article] Analysis of Humoral Immune Response in Experimental Autoimmune Pancreatitis in Mice2010
- Author(s)
  Asada M, Nishio A, Akamatsu T, Tanaka J, Saga K, Kido M, Watanabe N, Uchida K, Fukui T, 他2名
- Journal Title
  
  Pancreas 39
  
  Pages: 224-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Analysis of regulatory T cells and IgG4-positive plasma cells among patients of IgG4-related sclerosing cholangitis and autoimmune liver diseases2010
- Author(s)
  Koyabu M, Uchida K, Miyoshi H, Sakaguchi Y, Fukui T, 他7名
- Journal Title
  
  J Gastroenterol (Epub ahead of print)
- NAID
  10026707041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Endoscopic Biliary Plastic Stenting and Successful Intentional Stent Ret rieval in a Benign Biliary Stricture with Mural Spherical Calcification and Porcelain Gallbladder2009
- Author(s)
  Fukui T
- Journal Title
  
  Intern Med 48(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Long-term outcome of autoimmune pancreatitis2009
- Author(s)
  Uchida K, Yazumi S, Nishio A, Kusuda T, Koyabu M, Fukata M, Miyoshi H, Sakaguchi Y, Fukui T, 他3名
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 726-732
- NAID
  10025176191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Endoscopic biliary plastic stenting and successful intentional stent retrieval in a benign biliary stricture with mural spherical calcification and porcelain gallbladder2009
- Author(s)
  Fukui T, 他7名
- Journal Title
  
  Intern Med. 48
  
  Pages: 809-813
- NAID
  130000121780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Gastric mucosal laceration: a complication of manual bag-valve-mask ventilation2008
- Author(s)
  Fukui T, 他4名
- Journal Title
  
  Clin J Gastroenterol 1
  
  Pages: 56-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis2008
- Author(s)
  Okazaki K, Uchida K, Fukui T.
- Journal Title
  
  J Gastroenterol 43
  
  Pages: 409-418
- NAID
  10021268863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] 【H. pylori感染と上部消化器疾患】病態との関連を巡ってAcid-peptic disorderから腫瘍性疾患までヘリコバクター胃炎におけるCD8陽性細胞の役割-MHC class 2欠損マウスを用いた検討-2008
- Author(s)
  福井寿朗, 他3名
- Journal Title
  
  消化器医学 6
  
  Pages: 14-20
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] Gastric mucosal laceration : a complication of manual bag-valve-mask ventilation2008
- Author(s)
  Fukui T
- Journal Title
  
  Clin J Gastroenterol 1
  
  Pages: 56-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790516
[Journal Article] ヘリコバクター胃炎におけるCD8陽性細胞の役割--MHC class 2欠損マウスを用いた検討--2008
- Author(s)
  福井寿朗
- Journal Title
  
  消化器医学 6
  
  Pages: 14-20
- Data Source
  KAKENHI-PROJECT-20790516
[Presentation] pSmad2/3L-Thr発現に着目した食道腫瘍の発癌・進展機構解析と臨床応用2022
- Author(s)
  福井寿朗堀谷俊介長沼誠
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K08020
[Presentation] 腸炎関連大腸癌モデルマウスにおけるSmad2/3蛋白リンカー部リン酸化の発癌との関連性についての検討2016
- Author(s)
  福井寿朗
- Organizer
  第7回日本炎症性腸疾患学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-07-08
- Data Source
  KAKENHI-PROJECT-16K09330
[Presentation] 特定のリンカー部スレオニンがリン酸化されたSmad2/3蛋白(pSmad2/3L-Thr)の消化管上皮幹細胞マーカーとしての検討と応用2016
- Author(s)
  福井寿朗
- Organizer
  第53回日本臨床分子医学会　学術集会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-16K09330
[Presentation] Carcinogenic and stem cell-like phenotypes of Smad2/3 linker phosphorylation in a mouse model of colitis-associated colorectal cancer.2015
- Author(s)
  Toshiro Fukui, Ryo Suzuki, Masanobu Kishimoto, Kazuichi Okazaki
- Organizer
  GI Research Academy 2015
- Place of Presentation
  ロイヤルパークホテル（東京）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] 小腸幹細胞様細胞マーカーとしてのpSmad2/3-L-Thrの可能性の検討2015
- Author(s)
  福井寿朗　岸本真房　鈴木亮高橋悠　宮本早知　松本泰司　谷村雄志内田一茂　西尾彰功　岡崎和一
- Organizer
  第53回小腸研究会
- Place of Presentation
  アイーナ（いわて県民情報交流センター）（岩手県・盛岡市）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] 特定のリンカー部スレオニンがリン酸化されたSmad2/3蛋白（pSmad2/3L-Thr）の消化管上皮幹細胞マーカーとしての検討と応用2015
- Author(s)
  高橋悠　福井寿朗　岡崎和一
- Organizer
  第103回日本消化器病学会近畿支部例会　ワークショップ2　次代を担う消化器研究　bench to bed
- Place of Presentation
  大阪国際交流センター　大阪市
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] Carcinogenic and stem cell-like phenotypes of Smad2/3 linker phosphorylation in a mouse model of colitis-associated colorectal cancer.2015
- Author(s)
  Toshiro Fukui, Ryo Suzuki, Masanobu Kishimoto, Yu Takahashi, Sachi Miyamoto, Kazushige Uchida, Akiyoshi Nishio, Kazuichi Okazaki
- Organizer
  APDW (Asian Pacific Digestive Week) 2015
- Place of Presentation
  Taipei International Convention Center, Taipei, Taiwan
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] Phosphorylation of Smad2/3 in Stem Cells of Small Intestine2013
- Author(s)
  Yu Takahashi, Toshiro Fukui, Ryo Suzuki, Masanobu Kishimoto, Kazushige Uchida, Koichi Matsuzaki, Akiyoshi Nishio, Kazuichi Okazaki
- Organizer
  21th United European Gastroenterology Week
- Place of Presentation
  Internationales Congress Centrum Berlin, Berlin, Germany
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] リンカー部スレオニンリン酸化smad2/3蛋白発現による腸管幹細胞マーカーの探索2013
- Author(s)
  岸本真房　鈴木亮　高橋悠　福井寿朗　坂口雄沢　内田一茂　西尾彰功　岡崎和一
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25460938
[Presentation] 消化管上皮細胞におけるリン酸化Smad蛋白発現の検討と消化管幹細胞<ヘリコバクター胃炎モデルマウスについての検討を中心に>2011
- Author(s)
  福井寿朗
- Organizer
  第6回Bay Area Gut Club (BAG)
- Place of Presentation
  ホテルグランヴィア大阪(大阪府)
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-22790676
[Presentation] The specific linker phosphorylation of Smad2/3 might indicate opithelial stem cells in stomach ; particularly increasing in mucosae of Helicobacter-associated gastritis2011
- Author(s)
  Toshiro Fukui
- Organizer
  GI Research Academy 2011
- Place of Presentation
  The Westin Miyako Kyoto, Kyoto, Japan
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22790676
[Presentation] The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in colon; particularly increasing in the regeneration phase of murine model of dextran sulfate sodium-induced colitis
- Author(s)
  Toshiro Fukui
- Organizer
  GI Research Academy 2012
- Place of Presentation
  KEIDANREN KAIKAN, (Tokyo)
- Data Source
  KAKENHI-PROJECT-22790676

1. OKAZAKI Kazuichi (70145126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. UCHIDA Kazushige (40411516)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. MATSUZAKI Koichi (70278638)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NISHIO Akiyoshi (50362463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. KISHIMOTO Masanobu

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. TKAHASHI Yu

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. SUZUKI Ryo

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. MIYOSHI Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FUKATA Norimasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. KOYABU Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MIYAMOTO Sachi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUMOTO Yasushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANIMURA Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUKUI Toshiro 福井 寿朗

福井 寿朗 フクイ トシロウ

Research Projects

Research Products

Co-Researchers

Analyses and clinical applications of carcinogenic and progression mechanisms of gastrointestinal cancers focusing on pSmad2/3L-Thr expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of cancer stem cells and appearance, development and progression of cancer lesions focusing on phosphorylation of the linker region of Smad2/3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the epithelial stem cell and the regenerative and carcinogenic mechanisms of digestive tract from the point of view of pSmad2/3L-ThrPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of a biomarker of the epithelial stem cell and analysis of the regenerative and carcinogenic mechanisms of digestive tractPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of relationships of lymphocyte differentiation, gastric mucosal immune response, and carcinogenic mechanism to signaling cascade of TGF-β.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 見て診て学ぶ膵腫瘍の画像診断2009

Author(s)

Publisher

Data Source

[Journal Article] A Short-Term Model of Colitis-Associated Colorectal Cancer That Suggests Initial Tumor Development and the Characteristics of Cancer Stem Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Carcinogenic and stem cell-like phenotypes of Smad2/3 linker phosphorylation in a mouse model of colitis-associated colorectal cancer2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Phosphorylation of Smad2/3 at Specific Linker Threonine Indicates Slow-Cycling Intestinal Stem-Like Cells Before Reentry to Cell Cycle2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylation of Smad2/3 at the specific linker threonine residue indicates slow-cycling esophageal stem-like cells before re-entry to the cell cycle2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach ; particularly increasing in mucosae of Helicobacter-associated gastritis2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The specific linker phosphorylation of Smad2/3 indicates epithelial stem cells in stomach ; particularly increasing in mucosae of Helicobacter-associated gastritis.2011

Author(s)

Journal Title

FUKUI Toshiro 福井寿朗

福井寿朗フクイトシロウ