OJIMA Koichi 尾嶋孝一

Researcher Number	60415544
Other IDs
Affiliation (Current)	2024: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員
Affiliation (based on the past Project Information) *help	2016 – 2024: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員 2016: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門畜産物研究領域, 上級研究員 2014: 独立行政法人農業, 食品産業技術総合研究機構・畜産草地研究所, 畜産物研究領域 2013 – 2014: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所畜産物研究領域, 研究員 2012 – 2014: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所畜産物研究領域, 主任研究員 … More 2012: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所・畜産物研究領域, 研究員 2012: 畜産草地研究所, 畜産物研究領域, 主任研究員 2010 – 2012: National Agricultural Research Organization, 畜産草地研究所, 研究員 2011: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所畜産物研究領域, 主任研究員 2010: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所・畜産物領域, 主任研究員 2010: 独立行政法人農業・食品産業技術総合研究機構, 畜産草地研究所・食肉プロテオーム研究チーム, 研究員 2008 – 2009: National Agricultural Research Organization, 畜産草地研究所食肉プロテオーム研究チーム, 研究員 2007: 東京都臨床医学総合研究所, 研究員 2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 研究員 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related / Neurophysiology and muscle physiology / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Integrative animal science / Neurophysiology and muscle physiology Except Principal Investigator Basic Section 42010:Animal production science-related / Zootechnical science/Grassland science / Basic Section 42020:Veterinary medical science-related / Animal production science / Biological Sciences
Keywords	Principal Investigator 骨格筋 / カルパイン / p94 / 筋線維型 / 脂肪細胞 / 骨格筋細胞 / ウシ / 運動刺激 / 筋型 / 筋原線維 … More / ミオシン / プロテアーゼ / 蛋白質分解酵素 / タンパク質分解酵素 / 筋ジストロフィー / ナトリウム / 骨格箭 … More Except Principal Investigator 骨格筋 / 筋細胞 / 筋線維型 / 細胞外マトリックス / 細胞間コミュニケーション / 神経細胞 / 脂肪細胞 / 筋原線維 / 太いフィラメント / ミオシン / 細胞外マトリクス / 骨格筋間質 / 細胞分化 / 間葉系前駆細胞 / 筋間質 / コンドロイチン硫酸 / エストロゲン / 線維化 / ミトコンドリア異常 / 異常硬化胸肉 / ブロイラー / ニワトリ / 食肉 / メチル化 / 遅筋 / 速筋 / サルコメア / ミオシン分子 / アクチン / 細胞・組織 / 動物 / 畜産学 / エクソソーム / 筋衛星細胞 / 運動神経末端 / 運動神経 / 筋幹細胞 / 細胞間コミニュケーション / 家畜骨格筋 / 生理活性因子 / シグナル伝達 / ユビキチンリガーゼ / ノックインマウス / 筋ジストロフィー / モジュレータ・プロテアーゼ / メンブレン・トラフィック / プロテオリシス / 蛋白質 / 酵素 / 胃腸 / カルシウム / カルパイン / 細胞内タンパク質分解 Less

筋ミトコンドリア異常から始まり線維化に至るブロイラー異常胸肉発現機序の全容解明
- Principal Investigator
  
  岩崎智仁
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Rakuno Gakuen University
ホルモンと糖鎖から解き明かす骨格筋間質の機能維持機構
- Principal Investigator
  
  保坂善真
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kyushu University
筋線維型により異なる筋肥大・萎縮メカニズムをタンパク質分解酵素の観点から解明するPrincipal Investigator
- Principal Investigator
  
  尾嶋孝一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Agriculture and Food Research Organization
なぜウシ骨格筋組織内脂肪交雑の割合は黒毛和種で高いのか？Principal Investigator
- Principal Investigator
  
  尾嶋孝一
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  National Agriculture and Food Research Organization
運動ストレス応答にカルパインの酵素活性はなぜ必要なのか？Principal Investigator
- Principal Investigator
  
  尾嶋孝一
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Agriculture and Food Research Organization
The mechanism of myosin replacement in the thick filament of the skeletal muscle
- Principal Investigator
  
  Nishimura Takanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hokkaido University
Cell-cell comunication in developing skeletal muscle
- Principal Investigator
  
  NISHIMUTA TAKANORI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Animal production science
- Research Institution
  Hokkaido University
Myosin dynamics in cultured skeletal muscle cells and isolated fibersPrincipal Investigator
- Principal Investigator
  
  OJIMA Koichi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  National Agriculture and Food Research Organization
Cell-cell communications in developing skeletal muscle
- Principal Investigator
  
  NISHIMURA Takanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Hokkaido University
Developing sensor-proteins to detect CAPN3 protease activityPrincipal Investigator
- Principal Investigator
  
  OJIMA Koichi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  National Agriculture and Food Research Organization
Studies on thick filament formation during myofibrillogenesis
- Principal Investigator
  
  HATTORI Akihito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Hokkaido University
Skeletal muscle specific calpain p94 mediated signal transduction systemPrincipal Investigator
- Principal Investigator
  
  OJIMA Koichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  National Agricultural Research Organization
Biomodulation by calpain
- Principal Investigator
  
  SORIMACHI Hiroyuki
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  財団法人東京都医学研究機構
   Tokyo Metropolitan Organization for Medical Research
ナトリウムを介した骨格筋特異的カルパインp94によるシグナル伝達についてPrincipal Investigator
- Principal Investigator
  
  尾嶋孝一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Journal Article] Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament2022
- Author(s)
  Ichimura Emi、Ojima Koichi、Muroya Susumu、Kobayashi Ken、Nishimura Takanori
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 4 Pages: 852-863
- DOI
  10.1002/2211-5463.13379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03100
[Journal Article] Endogenous slow and fast myosin dynamics in myofibers isolated from mice expressing GFP-Myh7 and Kusabira Orange-Myh12022
- Author(s)
  Ojima Koichi、Kigaki Masahiro、Ichimura Emi、Suzuki Takahiro、Kobayashi Ken、Muroya Susumu、Nishimura Takanori
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 323 Issue: 2 Pages: C520-C535
- DOI
  10.1152/ajpcell.00415.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05955, KAKENHI-PROJECT-19H03100
[Journal Article] Myosin: Formation and maintenance of thick filaments.2019
- Author(s)
  K. Ojima
- Journal Title
  
  Animal Science Journal
  
  Volume: 90 Issue: 7 Pages: 801-807
- DOI
  10.1111/asj.13226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08079
[Journal Article] HSP90 modulates the myosin replacement rate in myofibrils2018
- Author(s)
  Ojima Koichi, Ichimura Emi, Suzuki Takahiro, Oe Mika, Muroya Susumu, Nishimura Takanori
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: in press Issue: 1 Pages: C104-C114
- DOI
  10.1152/ajpcell.00245.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08079, KAKENHI-PROJECT-16K18788
[Journal Article] 骨格筋量を制御する細胞分子メカニズムに関する研究　-基礎的な観点から骨格筋形成を研究する-2018
- Author(s)
  尾嶋孝一
- Journal Title
  
  畜産技術
  
  Volume: 759 Pages: 2-5
- Data Source
  KAKENHI-PROJECT-16K08079
[Journal Article] The myosin substitution rate is affected by the amount of cytosolic myosin in cultured muscle cells2017
- Author(s)
  Koichi OJIMA, Emi ICHIMURA, Yuya YASUKAWA, Mika OE, Susumu MUROYA, Takahiro SUZUKI, Jun-ichi WAKAMATSU, and Takanori NISHIMURA
- Journal Title
  
  Animal Science Journal
  
  Volume: 印刷中 Issue: 11 Pages: 1788-1793
- DOI
  10.1111/asj.12826
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08079, KAKENHI-PROJECT-16K18788
[Journal Article] Dynamics of protein secretion during adipocyte differentiation2016
- Author(s)
  Ojima K, Oe M, Nakajima I, Muroya S, Nishimura T
- Journal Title
  
  FEBS Open Bio
  
  Volume: 6 Issue: 8 Pages: 816-826
- DOI
  10.1002/2211-5463.12091
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02585
[Journal Article] Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction2014
- Author(s)
  Ojima, K. Ono, Y. Hata, S. Noguchi, S. Nishino, I. Sorimachi, H.
- Journal Title
  
  Genes to Cells
  
  Volume: 19 Issue: 11 Pages: 830-841
- DOI
  10.1111/gtc.12181
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23500477, KAKENHI-PROJECT-26450172
[Journal Article] 筋幹細胞が分泌するSema3Aによる筋線維型自律制御機構2014
- Author(s)
  鈴木貴弘, 大屋雄暉, 尾嶋孝一, 大坪秀明, 小宮佑介, 水野谷航, 中村真子, 池内義秀, 古瀬充宏, 辰巳隆一
- Journal Title
  
  栄養生理研究会報
  
  Volume: 58 Pages: 19-25
- NAID
  40020020774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24248045
[Journal Article] Proteomic analysis of secreted proteins from skeletal muscle cells during differentiation2014
- Author(s)
  Ojima K, Oe M, Nakajima I, Shibata M, Chikuni K, Muroya S, and Nishimura T.
- Journal Title
  
  EuPA Open Proteomics
  
  Volume: 5 Pages: 1-9
- DOI
  10.1016/j.euprot.2014.08.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24248045
[Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles2011
- Author(s)
  Ojima, K., Ono, Y., Ottenheijm, C., Hata, S., Suzuki, H., Granzier, H., Sorimachi, H.
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 407 Pages: 439-449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011
- Author(s)
  K.Ojima, Y.Ono, C.Ottenheijm, S.Hata, H.Suzuki, H.Granzier, H.Sorimachi.
- Journal Title
  
  J.Mol.Biol. 407
  
  Pages: 439-449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles.2011
- Author(s)
  Ojima K, Ono Y, Ottenheijm C, HataS, Suzuki H, Granzier H, Sorimachi H
- Journal Title
  
  J Mol Biol
  
  Volume: 407 Issue: 3 Pages: 439-449
- DOI
  10.1016/j.jmb.2011.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139, KAKENHI-PROJECT-23247021
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010
- Author(s)
  Ojima K, Kawabata Y, Nakao H, Nakao K, Doi N, Kitamura F, Ono Y, HataS, Suzuki H, Kawahara H, Bogomolovas J,Will C, Ottenheijm C, LabeitS, Granzier H, Toyama-Sorimachi N, Sorimachi M, Suzuki K, Maeda T, Abe K, Aiba A, Sorimachi H
- Journal Title
  
  J Clin Invest
  
  Volume: 120 Issue: 8 Pages: 2672-2683
- DOI
  10.1172/jci40658
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22770139
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy2010
- Author(s)
  Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Bogomolovas, J., Witt, C., Ottenheijm, C., Labeit, S., Granzier, H., Toyama-Sorimachi, N., Sorimachi, M., Suzuki, K., Maeda, T., Abe, K., Aiba, A., Sorimachi, H.
- Journal Title
  
  J.Clin.Invest.
  
  Volume: 120 Pages: 2672-2683
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.2010
- Author(s)
  K.Ojima, Y.Kawabata, H.Nakao, K.Nakao, N.Doi, F.Kitamura, Y.Ono, S.Hata, H.Suzuki, H.Kawahara, J.Bogomolovas, C.Witt, C.Ottenheijm, S.Labeit, H.Granzier, N.Toyama-Sorimachi, M.Sorimachi, K.Suzuki, T.Maeda, K.Abe, A.Aiba, H.Sorimachi.
- Journal Title
  
  J.Clin.Invest. 120
  
  Pages: 2672-2683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease.2010
- Author(s)
  Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 30 Pages: 22986-22998
- DOI
  10.1074/jbc.m110.126946
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007, KAKENHI-PROJECT-22770139
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.2010
- Author(s)
  Y.Ono, K.Ojima, F.Torii, E.Takaya, N.Doi, K.Nakagawa, S.Hata, K.Abe, H. Sorimachi.
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dysirophy2010
- Author(s)
  Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Suzuki, H., Kawahara, H., Bogomolovas, J., Witt, C., Ottenbeijm, C., Labeit, S., Granzier, H., Toyama-Smorimachi, N., Sorimachi, M., Suzuki, K., Macda, T., Abe, K., Aiba, A., Sorimachi, H.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 120 Pages: 2672-2683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500369
[Journal Article] Skeletal muscle-specific calpain is an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., Sorimachi, H.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 22986-22998
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Skeletal muscle-specific calpain, p94/calpain-3, dynamically distributes in skeletal muscle cells to adapt to physical stress, defects of which cause muscular dystrophy.2010
- Author(s)
  Ojima K, Ono Y, Doi N, Kitamura F, Kawabata Y, Suzuki K, Maeda T, Abe K, Nakao H, Aiba A, Suzuki H, Kawahara H, Witt C,Ottenheijm C, Labeit S, Ottenheijm C, Granzier H, Toyama-Sorimachi N, Sorimachi M, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 20 Pages: 598-599
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Redundant and non-redundant effects of Ca^<2+> and Na^+ on the activation of p94/calpain-3.2010
- Author(s)
  Ono Y, Ojima K, Torii F, Takaya E, Doi N, Nakagawa K, Hata S, Abe K, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 20 Pages: 608-608
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Muscle RING-finger protein MuRF1 as a connector of muscle energy metabolism and protein synthesis2008
- Author(s)
  Koyama, S., Hata, S., Witt, C. C. , Ono, Y., Lerche, S., Ojima, K., Chiba, T., Doi, N., Kitamura, F., Tanaka, K., Abe, K., Witt, S., Rybin, V., Gasch, A., Franz, T., Labeit, S., Sorimachi, H
- Journal Title
  
  J. Mol. Biol 376
  
  Pages: 1224-1236
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Muscle RING-Finger protein(MuRFl)as a connector of muscle energy metabolism and protein synthesis2008
- Author(s)
  S.Koyama, S.Hata, C.Witt, Y.Ono, S.Lerche, K.Ojima, T.Chiba, N.Doi, F.Kitamura, K.Tanaka, K.Abe, S.Witt, V.Rybin, A.Gasch, T.Franz, S.Labeit, and H.Sorimachi.
- Journal Title
  
  Journal of Molecular Biology 36
  
  Pages: 1224-12136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700392
[Journal Article] Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis.2008
- Author(s)
  Koyama S, HataS, Witt CC, Ono Y, Lerche S, Ojima K, Chiba T, Doi N, Kitamura F, Tanaka K, Abe K, Witt SH, Rybin V, Gasch A, Franz T, Labeit S, Sorimachi H
- Journal Title
  
  J Mol Biol
  
  Volume: 376 Issue: 5 Pages: 1224-1236
- DOI
  10.1016/j.jmb.2007.11.049
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain.2007
- Author(s)
  Ojima K, Ono Y, Doi N, Yoshioka K, Kawabata Y, Labeit S, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 282 Issue: 19 Pages: 14493-14504
- DOI
  10.1074/jbc.m610806200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Myogenic stage, sarcomere length and protease activity modulate localization ofmuscle-specific calpain2007
- Author(s)
  Ojima, K., Ono, Y., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, S., Sorimachi, H
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 14493-14504
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.2006
- Author(s)
  Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, LabeitS, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  J Biol Chem
  
  Volume: 281 Issue: 27 Pages: 18519-31
- DOI
  10.1074/jbc.m601029200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006
- Author(s)
  Sorimachi H, Ojima K, Yanagida M, Ogawa H, Hayashi C, Doi N, Ono Y
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Effect of N2A connectin/titin on disassembly of p94/CAPN3 caused by auaolysis in IS2.2006
- Author(s)
  Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  FEBS Journal
  
  Volume: 273 Supp1. Issue: s1 Pages: 50-50
- DOI
  10.1111/j.1742-4658.2006.05276.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Spatio-temporal expression of muscle-specific calpain, p94/calpain 3, during myogenesis.2006
- Author(s)
  Ojima K, Ono Y, Doi N, Labeit S, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 by N2A connectin/titin in a genetic reporter system.2006
- Author(s)
  Ono Y, Torii F, Ojima K, Doi N, Yoshioka K, Kawabata Y, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 18519-18531
- Data Source
  KAKENHI-PROJECT-18700392
[Journal Article] Suppressed disassembly of autolyzing p94/CAPN3 in a genetic reporter system2006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki,K., Abe, K., Maeda, T., Sorimachi, H
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 18519-18531
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Journal Article] Relationships between p94/CAPN3 and N2A connectin/titin in skeletal muscle under the normal and dystrophic conditions.2006
- Author(s)
  Ono Y, Ojima K, Doi N, Hayashi C, Torii F, 40K, Labeit D, Labeit S, Suzuki K, Abe K, Maeda T, Sorimachi H
- Journal Title
  
  Neuromuscul Disord
  
  Volume: 16
- URL
  http://www.elsevier.com/wps/find/journaldescription.cws_home/973/description.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] 筋原線維内太いフィラメントにおけるミオシン分子置換に及ぼすユビキチンリガーゼの影響2020
- Author(s)
  市村恵美、尾嶋孝一、鈴木貴弘、小林謙、西邑隆徳
- Organizer
  127回日本畜産学会
- Data Source
  KAKENHI-PROJECT-19H03100
[Presentation] Embryonic Myosin replacement in myofibrils is controlled through degradation and ubiquitination by a ubiquitin ligase, Ozz2020
- Author(s)
  E. Ichimura, K. Ojima, S. Muroya, T. Suzuki, K. Kobayashi, T. Nishimura
- Organizer
  CELL BIO virtual 2020, An Online American Society of Cell Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03100
[Presentation] The replacement of myosin molecules in thick filaments is different between slow- and fast-twitch myofibers.2019
- Author(s)
  M. Kigaki, K. Ojima, T. Suzuki, K. Kobayashi, T. Nishimura
- Organizer
  American Society for Cell Biology (ASCB) 58th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03100
[Presentation] 速筋型および遅筋型筋線維のゲノムDNAのメチル化解析2019
- Author(s)
  大江美香, 尾嶋孝一, 室谷進
- Organizer
  日本畜産学会第125回大会
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] The replacement of myosin molecules in thick filaments is different between slow- and fast-twitch myofibers.2019
- Author(s)
  M. Kigaki, K. Ojima, T. Suzuki, K. Kobayashi, T. Nishimura
- Organizer
  2019 ASCB EMBO meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] FRET-based probes capture muscle-specific calpain-3 (CAPN3) activity in myotubes.2019
- Author(s)
  K. Ojima, S. Hata, F. Shinkai-Ouchi, M. Oe, S. Muroya, H. Sorimachi, Y. Ono.
- Organizer
  FASEB Science Research Conference, The Biology of Calpains in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04014
[Presentation] 筋幹細胞の合成・分泌因子 Netrin-1による速筋型筋線維の形成誘導2019
- Author(s)
  鈴木貴弘・森愛華・久枝皓雅・西百合子・有松里央・小林謙・辰巳隆一・尾嶋孝一・西邑隆徳
- Organizer
  日本畜産学会第125回大会
- Data Source
  KAKENHI-PROJECT-16H02585
[Presentation] 骨格筋萎縮　－タンパク質分解酵素カルパインの観点から－2019
- Author(s)
  尾嶋　孝一
- Organizer
  日本畜産学会第126回大会　日本畜産学会若手企画委員会主催ランチョンセミナー　みんなで筋肉勉強 -筋肥大と筋萎縮-
- Invited
- Data Source
  KAKENHI-PROJECT-19H04014
[Presentation] 骨格筋細胞が分泌する因子の網羅的な解析2018
- Author(s)
  尾嶋孝一
- Organizer
  第6回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-16H02585
[Presentation] 骨格筋細胞におけるミオシン分子のダイナミクス2018
- Author(s)
  尾嶋孝一
- Organizer
  第161回日本獣医学会学術集会獣医解剖分科会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02585
[Presentation] 骨格筋の量と質を制御する細胞分子メカニズムに関する研究2018
- Author(s)
  尾嶋孝一
- Organizer
  日本畜産学会第124回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] 骨格筋細胞におけるミオシン分子のダイナミクス2018
- Author(s)
  尾嶋孝一
- Organizer
  第161回日本獣医学会学術集会　獣医解剖分科会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] 筋原線維に組み込まれていないミオシン分子の量が太いフィラメントのミオシン分子置換に及ぼす影響2017
- Author(s)
  尾嶋孝一、市村恵美、安川裕也、室谷進、鈴木貴弘、西邑隆徳
- Organizer
  日本畜産学会第122回大会
- Place of Presentation
  神戸大学　（兵庫県・神戸市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] 骨格筋筋原線維内ミオシン分子の置換はHsp90により促進される2017
- Author(s)
  尾嶋孝一, 市村恵美, 大江美香, 室谷進, 鈴木貴弘, 西邑隆徳
- Organizer
  日本畜産学会第123回大会
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] Myosin replacement in myofibrils is induced by Hsp90 activity2017
- Author(s)
  K. Ojima, E. Ichimura, S. Muroya, M. Oe, T. Suzuki, T. Nishimura
- Organizer
  2017 ASCB EMBO meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08079
[Presentation] カルパイン3-タンパク質分解酵素の活性不全による骨格筋変性-2014
- Author(s)
  尾嶋孝一
- Organizer
  第157回日本獣医学会学術集会【日本獣医解剖学会シンポジウム】「細胞形態ダイナミクスをリードする分子群を求めて」
- Place of Presentation
  札幌市
- Year and Date
  2014-09-10
- Invited
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] 筋原線維の太いフィラメント内でミオシン分子はダイナミックに置き換わっている2013
- Author(s)
  安川裕也, 尾嶋孝一, 若松純一, 服部昭仁, 西邑隆徳
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  安田女子大学（広島市）
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] Identification of phosphorylation sites of muscle-specific calpain-32013
- Author(s)
  Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
- Organizer
  FASEB Science Research Conferences, The Biology of Calpains in Health and Disease
- Place of Presentation
  Saxton River, VT, USA
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] 骨格筋細胞におけるミオシン分子の太いフィラメント形成能2013
- Author(s)
  尾嶋孝一, 中島郁世, 大江美香, 室谷進, 服部昭仁, 西邑隆徳
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  安田女子大学（広島市）
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] 筋原線維の太いフィラメント内でミオシン分子はダイナミックに置き換わっている2013
- Author(s)
  安川裕也,尾嶋孝一,若松純一,服部昭仁,西邑隆徳
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  広島市安田女子大学
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] Effects of phosphorylation of muscle-specific calpain-3 on its proteolytic activity.2013
- Author(s)
  Koichi Ojima, Yasuko Ono, Shoji Hata, Oe Mika, Ikuyo Nakajima, Susumu Muroya, Koichi Chikuni, Hiroyuki Sorimachi
- Organizer
  2013 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  NewOrleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Semaphorin 3A secreted from myogenic stem cells promotes slow-twitch muscle fiber generation2013
- Author(s)
  Takahiro Suzuki, Koichi Ojima, Mai-Khoi Q. Do, Minako Hara, Wataru Mizunoya, Mako Nakamura, Yoshihide Ikeuchi, Judy E. Andeson, Ryuichi Tatsumi
- Organizer
  2013 EMBO Workshop on “Semaphorin Function and Mechanism in Action”
- Place of Presentation
  Cemay-la-Ville, France
- Year and Date
  2013-10-30
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] カルパイン3のリン酸化が酵素活性に与える影響2013
- Author(s)
  尾嶋孝一, 小野弥子, 秦勝志, 大江美香, 中島郁世, 千国幸一, 室谷進, 反町洋之
- Organizer
  日本畜産学会第117回大会
- Place of Presentation
  新潟市
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] 骨格筋細胞におけるミオシン分子の太いフィラメント形成能2013
- Author(s)
  尾嶋孝一,中島郁世,大江美香,室谷進,服部昭仁,西邑隆徳
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  広島市安田女子大学
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] 筋幹細胞由来の分泌因子Sema3Aによる筋線維型自律制御機構の解明2013
- Author(s)
  鈴木貴弘, 尾嶋孝一, 大屋雄暉, 大坪秀明, 水野谷航, 中村真子, 池内義秀, 辰巳隆一
- Organizer
  第117回日本畜産学会大会
- Place of Presentation
  新潟大学（新潟市）
- Year and Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] Myosin dynamicsin cultured skeletal muscle cells.2012
- Author(s)
  Yasukawa, Y., Ojima, K., Wakamatsu, J.-i.,Hattori, A., and Nishimura, T.
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  The Moscone Center, San Francisco, USA.
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] Myosin dynamics in cultured skeletal muscle cells2012
- Author(s)
  Y. Yasukawa, K. Ojima, J. Wakamatsu, A. Hattori, T. Nishimura
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco convention center (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] The impact of each domain of myosin heavy chain molecule on forming thick filaments in muscle and non-muscle cells.2012
- Author(s)
  K. Ojima, I. Nakajima, M. Oe, S. Muroya, T. Nishimura, A. Hattori.
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco convention center (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] The impact of each domain of myosin heavy chain molecule on forming thick filaments in muscle and non-muscle cells.2012
- Author(s)
  Ojima, K., Nakajima, I., Oe, M., Muroya, S.,Nishimura, T., and Hattori, A.
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  The Moscone Center, San Francisco, USA.
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PROJECT-22580301
[Presentation] 骨格筋特異的に発現するカルパイン3はNa+により活性化する2012
- Author(s)
  尾嶋孝一, 小野弥子, 中島郁世, 大江美香, 室谷進 , 反町洋之
- Organizer
  日本畜産学会第115回大会
- Place of Presentation
  名古屋大学（愛知県）
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Studies of titin signaling and CAPN3.2011
- Author(s)
  Sorimachi, H., Ojima, K., and Ono, Y.
- Organizer
  LGMD2A Workshop: Coalition to Cure Calpain 3(C3)
- Place of Presentation
  Santa Monica, USA.
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Unique properties of muscle-specific calpain and muscular dystrophy caused by its defect.2011
- Author(s)
  Sorimachi, H., Ojima, K., and Ono, Y.
- Organizer
  IPS2011 - Seventh General Meeting of the International Proteolysis Society
- Place of Presentation
  San Diego, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Structural functions of skeletal muscle-specific calpain in Ca2+ efflux from the sarcoplasmic reticulum2011
- Author(s)
  Koichi Ojima, Yasuko Ono, Coen Ottenheijm, Shoji Hata, Hidenori Suzuki, Mika Oe, Ikuyo Nakajima, Susumu Muroya, Henk Granzier, and Hiroyuki Sorimachi
- Organizer
  2011 Annual Meeting of the American Society for Cell Biology.
- Place of Presentation
  Denver, CO. (USA)
- Data Source
  KAKENHI-PROJECT-23500477
[Presentation] Skeletal muscle-specific calpain is an intracellular Ca^<2+> and Na^+-dependent protease.2011
- Author(s)
  Sorimachi, H., Ojima, K., Takaya, E., and Ono Y.
- Organizer
  CaBP17 - The 17th International Symposium on Ca^<2+>-binding proteins and Ca^<2+> function in health and disease.
- Place of Presentation
  Beijing, China.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Dynamic distribution of muscle-specific calpain 3/p94 plays a key role in physical-stress adaptation and its defects by loss of activity cause muscular dystrophy.2010
- Author(s)
  Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Kawahara, H., Labeit, S., Toyama-Sorimachi, N., Sorimachi, M., Suzuki, K., Maeda, T., Aiba, A., Sorimachi, H.
- Organizer
  The Biology of Calpians in Health and Disease. FASEB Summer Research Conference
- Place of Presentation
  Carefree, AZ, USA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Unique functions of mammalian unconventional calpains.2010
- Author(s)
  Sorimachi, H., Hata, S., Ojima, K., Labeit, S., and Ono, Y.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Arizona, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Loss of calpain-3 protease activity impairs its distribution and muscle physical-stress adaption, resulting in muscular dystrophy.2010
- Author(s)
  Ojima, K., Kawabata, Y., Nakao, H., Nakao, K., Doi, N., Kitamura, F., Ono, Y., Hata, S., Kawahara, H., Labeit, S., Toyama-Sorimachi, N., Sorimachi, M., Maeda, T., Aiba, A., Sorimachi., H.
- Organizer
  The 50th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Philadelphia, PA.USA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Dynamic distribution of muscle-specific calpain 3/p94 plays a key role in physical-stress adaptation and its defects by loss of activity cause muscular dystrophy.2010
- Author(s)
  K.Ojima, Y.Kawabata, H.Nakao, K.Nakao, N Doi, F.Kitamura, Y.Ono, S.Hata, H.Kawahara, S.Labeit, N.Toyama-Sorimachi, M.Sorimachi, K.Suzuki, T.Maeda, A.Aiba, H.Sorimachi.
- Organizer
  The Biology of Calpians in Health and Disease. FASEB Summer Research Conference.
- Place of Presentation
  Carefree, AZ, USA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] (Selected for oral presentation) Characteristics of p94/calpain 3 as an intracellular Na^+-dependent protease2010
- Author(s)
  Ono, Y., Ojima, K., Torii, F., Takaya, E., Doi, N., Nakagawa, K., Hata, S., Abe, K., and Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Arizona, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Loss of calpain-3 protease activity impairs its distribution and muscle physical-stress adaption, resulting in muscular dystrophy.2010
- Author(s)
  K.Ojima, Y.Kawabata, H.Nakao, K.Nakao, N.Doi, F.Kitamura, Y.Ono, S.Hata, H.Kawahara, S.Labeit, N.Toyama-Sorimachi, M.Sorimachi, T.Maeda, A.Aiba, H.Sorimachi.
- Organizer
  The 50th Annual Meeting of the American Society for Cell Biology.
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] The closing lecture]In Memoriam Koichi Suzuki: Calpains in muscles and stomach XIIth Symposium on Proteases2010
- Author(s)
  Ono, Y., Hata, S., Ojima, K., Tonami, K., Kitamura, F., Ueno, M., Takaya, E., Granzier, H., Labeit, S., and Sorimachi, H.
- Organizer
  Inhibitors and Biological Control
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Quantitative mass spectrometry-based protein profiling of skeletal muscle cell differentiation in vitro.2009
- Author(s)
  K.Ojima, I.Nakajima, M.Oe, M.Shibata, H.Sorimachi, K.Chikuni.
- Organizer
  The 49th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Calpain-3 and molecular interactions. Calpaines et Calpainopathies.2009
- Author(s)
  Sorimachi, H., Ojima, K., Hata, S., andOno, Y.
- Organizer
  VIIes Journees annuelles de la SFM(Societe Francaise de Myologie)
- Place of Presentation
  Hendaye, France.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] 骨格筋特異的カルパインの筋小胞体における機能2009
- Author(s)
  尾嶋孝一,小野弥子,土井菜穂子,北村ふじ子,秦勝志, S.Labeit, H.Granzier,千国幸一, 反町洋之
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸(兵庫)
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Quantitative mass spectrometry-based protein profiling of skeletal muscle cell differentiation in vitro.2009
- Author(s)
  Koichi Ojima
- Organizer
  The 49th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Diego, CA.USA
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] 骨格筋特異的カルパインの筋小胞体における機能2009
- Author(s)
  尾嶋孝一
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] 骨格筋特異的カルパインは運動負荷による筋損傷をプロテアーゼ活性により防御する2008
- Author(s)
  尾嶋孝一
- Organizer
  第8回日本蛋白質科学会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] カルパイン及びコネクチンの構造-病態生理相関(Structure-Pathophysiological-Function Relationships of Calpain and Connectin/Titin.)2008
- Author(s)
  反町洋之、小野弥子、尾嶋孝一、林智佳子、土井奈穂子、北村ふじ子、小山傑、楠畑かおり、秦勝志、Labeit, S.
- Organizer
  第8回日本蛋白質科学会年会シンポジウム「蛋白質の輪廻転生-セントラルドグマを超えて」
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Quantitative proteomic analysis of skeletal muscles subjected to exercise.2008
- Author(s)
  K.Ojima, H.Sorimachi.
- Organizer
  The 48th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, CA
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Roles of skeletal muscle-specific calpain, p94/calpain 3, on multiple molecular interactions using connectin/titin N2A region as a modulating scaffold.2008
- Author(s)
  Sorimachi, H., Hayashi, C., Hata, S., Ojima, K., Koyama, S., Doi, N., Kitamura, F., Takaya, E., Ueno, M., Kaneko, N., and Ono, Y.
- Organizer
  11th International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] 骨格筋特異的カルパインは運動負荷による筋損傷をプロテアーゼ活性により防御する2008
- Author(s)
  尾嶋孝一,川畑順子,中尾晴美,小野弥子,土井菜穂子,北村ふじ子,秦勝志,川原裕之,C.Witt, S.Labeit,鈴木紘一,阿部啓子,前田達哉,餐場篤, 反町洋之
- Organizer
  第8回日本蛋白質科学会
- Place of Presentation
  江戸川区
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Quantitative proteomic analysis of skeletal muscles subjected to exercise2008
- Author(s)
  Koichi Ojima
- Organizer
  The 48th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, CA. USA
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-20500369
[Presentation] Toward Understanding Relationships between Proteolytic Activity of Skeletal Muscle-Specific Calpain and Calpainopathy.2007
- Author(s)
  Ono, Y., Ojima, K., Hata, S., and Sorimachi, H.
- Organizer
  2007 Korea-Japan Joint Symposium "Protein Modification and Degradation in Human Diseases"
- Place of Presentation
  Seoul, South Korea.
- Year and Date
  2007-09-05
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Unconventional calpains.2007
- Author(s)
  Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
- Organizer
  FASEB Summer Research Conferences - The Biology of Calpains in Health & Disease
- Place of Presentation
  Colorado, USA.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] Impact of proteolytic activity of muscle-specific calpain, p94/calpain3, on itslocalization in sarcomeres.2007
- Author(s)
  Ojima, K, Ono, Y., Doi, N, , Labeit, S., and Sorimachi, H.
- Organizer
  The American Society for. Cell Biology, the47th Annualmeeting
- Place of Presentation
  Washington,DC,USA.
- Data Source
  KAKENHI-PROJECT-18700392
[Presentation] Muscle specifie calpain. p94, binds to sarcomeric-α-actinin2007
- Author(s)
  Ojima, K, Ono, Y., Doi, N., Yoshioka, K, Kawabata, K., and Sorimachi, H
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡
- Year and Date
  2007-05-28
- Data Source
  KAKENHI-PROJECT-18700392
[Presentation] 骨格筋特異的なカルパインp94の遺伝子改変セゥスは筋ジストロフィー様の症状を呈する2007
- Author(s)
  尾嶋孝一, 川畑順子, 中尾晴美, 小野弥子土井奈穂子, 北村ふじ子, 秦勝志. 川原裕之, Christian Witt, Siegfride Labeit, 鈴木紘一, 阿部啓子, 前田達哉, 饗場篤, 反町洋之
- Organizer
  第12回病態と治療におけるプロテアーゼとインヒビター学会
- Place of Presentation
  大阪
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-18700392
[Presentation] Novel approaches for analysis of proteolytic activity of muscle-specific calpain p94/calpain 32007
- Author(s)
  Ono, Y., Ojima, K., Hayashi, C., Doi, N., Kitamura, F., Koyama, S., Hata, S., Labeit, S., Yanagida, M., Maeda, T., and Sorimachi, H.
- Organizer
  Xth International Symposium on PROTEINASE INHIBITORS AND BIOLOGICAL CONTROL: From single molecules to degradomics
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] 骨格筋特異的なカルパインp94/calpain 3のサルコメア長に依存した局在変化2007
- Author(s)
  尾嶋孝一, 小野弥子, 土井菜穂子, 吉岡克英, 川畑順子, Labeit, S., 反町洋之
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18700392
[Presentation] Myogenic stage, sarcomere length and protease activity modulate localization of muscle-specific calpain p94/calpain3.2007
- Author(s)
  Ojima, K., Ono, Y, Doi, N., Ybshioka, K., Kawabata, Y, Labebeit, S., and Sorinachi, H
- Organizer
  FASEB Summer Research Conferences-The Biology of Calpains in Healith & Disease
- Place of Presentation
  Colorado, USA.
- Year and Date
  2007-07-15
- Data Source
  KAKENHI-PROJECT-18700392
[Presentation] How do defects in proteolytic functions of skeletal muscle-specific calpain, p94/calpain 3, cause calpainopathy/LGMD2A?2006
- Author(s)
  Sorimachi, H., Ojima, K., Yanagida, M., Ogawa, H., Hayashi, C., Doi, N., and Ono, Y.
- Organizer
  XIth International Congress on Neuromuscular Diseases
- Place of Presentation
  Istanbul, Turkey.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] A novel genetic assay system for a rapidly autolyzing muscle-specific calpain p94/calpain 32006
- Author(s)
  Ono, Y., Torii, F., Ojima, K., Doi, N., Yoshioka, K., Kawabata, Y., Labeit, D., Labeit, S., Suzuki, K., Abe, K., Maeda, T., Hata, S., Koyama, S., and Sorimachi, H.
- Organizer
  5^<th> Internationla Conference on Cysteine Proteinases and Their Inhitbitors: From Structure to Regulation and Biology
- Place of Presentation
  Portoroz, Slovenia.
- Data Source
  KAKENHI-PLANNED-18076007
[Presentation] 筋芽細胞の増殖時・分化時におけるSema3AとPax7発現の相互作用
- Author(s)
  木　欄, 尾嶋孝一, 中村真子, 水野谷航, 辰巳隆一, 池内義秀
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮大学（宇都宮市）
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] Sema3A ligand secreted from satellite cells promotes aneural nAChR clustering
- Author(s)
  ドマイコイ, 水野谷航, 尾嶋孝一, 中村真子, 池内義秀, 辰巳隆一
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮大学（宇都宮市）
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] Functional interaction between Sema3A and Pax7 in proliferation and differentiation of myoblasts
- Author(s)
  Mulan, Nakamura, M., Suzuki, T., Mizunoya, W., Ojima, K., Tatsumi, R. and Ikeuchi, Y.
- Organizer
  International Symposium on Agriculture, Forestry, Environment and Life Sciences in Asia, 2014
- Place of Presentation
  Chuncheon, Gangwon, Korea
- Year and Date
  2014-10-28 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] 骨格筋細胞が増殖から分化に至る過程で分泌する因子のプロテオーム解析
- Author(s)
  尾嶋孝一, 大江美香, 中島郁世, 室谷進, 西邑隆徳
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮市（宇都宮大学）
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-24248045
[Presentation] Dynamics of secreted proteins from skeletal muscle cells during muscle differentiation
- Author(s)
  Ojima K, Oe M, Nakajima I, Muroya S, and Nishimura T.
- Organizer
  2014 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-24248045

1. NISHIMURA Takanori (10237729)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. HOSAKA Yoshinao (00337023)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. ONO Yasuko (20392376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
4. HATA Shoji (10392375)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. TATSUMI Ryuichi (40250493)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. 鈴木貴弘 (80750877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. 岩崎智仁 (30305908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SORIMACHI Hiroyuki (10211327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
9. HATTORI Akihito (50125027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 渡邉敬文 (50598216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 長谷川靖洋 (50807328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 田村純一 (30221401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIZUNOYA Wataru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OJIMA Koichi 尾嶋 孝一

Research Projects

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筋ミトコンドリア異常から始まり線維化に至るブロイラー異常胸肉発現機序の全容解明

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ホルモンと糖鎖から解き明かす骨格筋間質の機能維持機構

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筋線維型により異なる筋肥大・萎縮メカニズムをタンパク質分解酵素の観点から解明するPrincipal Investigator

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なぜウシ骨格筋組織内脂肪交雑の割合は黒毛和種で高いのか？Principal Investigator

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運動ストレス応答にカルパインの酵素活性はなぜ必要なのか？Principal Investigator

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The mechanism of myosin replacement in the thick filament of the skeletal muscle

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Cell-cell comunication in developing skeletal muscle

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Myosin dynamics in cultured skeletal muscle cells and isolated fibersPrincipal Investigator

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Cell-cell communications in developing skeletal muscle

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Developing sensor-proteins to detect CAPN3 protease activityPrincipal Investigator

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Studies on thick filament formation during myofibrillogenesis

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Skeletal muscle specific calpain p94 mediated signal transduction systemPrincipal Investigator

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Biomodulation by calpain

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OJIMA Koichi 尾嶋孝一

[Journal Article] 骨格筋量を制御する細胞分子メカニズムに関する研究　-基礎的な観点から骨格筋形成を研究する-2018