Nagai Takeshi 永井武

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NAGAI Takeshi 永井武

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Researcher Number	60418655
Affiliation (Current)	2026: 地方独立行政法人神奈川県立産業技術総合研究所, 「次世代ライフサイエンス技術開発」プロジェクト, 主任研究員
Affiliation (based on the past Project Information) *help	2012 – 2013: 慶應義塾大学, 医学部, 助教 2008 – 2010: Keio University, 医学部, 助教 2007: The University of Tokyo, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology)
Keywords	Principal Investigator 細菌感染 / 細菌 / T細胞 / 樹状細胞 / 感染免疫 / III型分泌機構 / 腸管病原性大腸菌 / 免疫学 / 微生物 / 腸管免疫 … More / 免疫 / 病原細菌 / 癌転移 / 癌 / 感染症 Less

Research Projects
(3 results)
Research Products
(18 results)

Type III effectors of Enteroopathogenic Escherichia coli (EPEC) regulate the host immunity.Principal Investigator
- Principal Investigator
  
  NAGAI Takeshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Keio University
Analysis of the interaction between enteropathogenic Escherichia coli infection and mucosal immunity in vitro and in vivoPrincipal Investigator
- Principal Investigator
  
  NAGAI Takeshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Keio University
Analysis of the tumor metastasis inhibited by Citrobacter rodentium infection and the investigation of bacterial anti-metastasis vaccine.Principal Investigator
- Principal Investigator
  
  NAGAI Takeshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Keio University
  The University of Tokyo

All 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] 「腸管出血性大腸菌感染症モデル」モデル動物使用マニュアル2012
- Author(s)
  永井武、小安重夫
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24790423
[Book] 疾患モデル作成と利用　糖尿病・肥満・感染症2012
- Author(s)
  永井武　小安重夫
- Total Pages
  220
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24790423
[Journal Article] Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo.2011
- Author(s)
  Chiba S, Nagai T, Hayashi T, Baba Y, Nagai S, Koyasu S.
- Journal Title
  
  Microbiol Immnnol
  
  Volume: 55 Pages: 123-129
- NAID
  10031121450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo.2011
- Author(s)
  Chiba S, Nagai T, Hayashi T, Baba Y, Nagai S, Koyasu S.
- Journal Title
  
  Microbiol Immunol vol.55
  
  Pages: 123-129
- NAID
  10031121450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] Asmall-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.2011
- Author(s)
  Kimura K, Iwatsuki M, Nagai T, Matsumoto A, Takahashi Y, Shiomi K, Omura S, Abe A.
- Journal Title
  
  J Antibiot vol.64
  
  Pages: 197-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.2011
- Author(s)
  Kimura K, Iwatsuki M, Nagai T, Matsumoto A, Takahashi Y, Shiomi K, Omura S, Abe A.
- Journal Title
  
  J Antibiot
  
  Volume: 64 Pages: 197-203
- NAID
  10030638108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] EspJ effector in enterohemorrhagic E. coli translocates into host mitochondria via an atypical mitochondrial targeting signal.2010
- Author(s)
  Kurushima J, Nagai T, Nagamatsu K, Abe A
- Journal Title
  
  Microbiol Immunol vol.54
  
  Pages: 371-379
- NAID
  10027847815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] EspJ effector in enterohemorrhagic E.coli translocates into host mitochondria via an atypical mitochondrial targeting signal.2010
- Author(s)
  Kurushima J, Nagai T, Nagamatsu K, Abe A.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 54 Pages: 371-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.2009
- Author(s)
  Kim M, Ogawa M, Fujita Y, Yoshikawa Y, Nagai T, Koyama T, Nagai S, Lange A, Fassler R, Sasakawa C
- Journal Title
  
  Nature vol.459
  
  Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790428
[Journal Article] Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses2009
- Author(s)
  Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y
- Journal Title
  
  Immunity 30
  
  Pages: 108-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790317
[Journal Article] Helicobacter pylori Dampens Gut Epithelial Self-Renewal by Inhibiting Apoptosis, a Bacterial Strategy to Enhance Colonization of the Stomach2007
- Author(s)
  Mimuro H, Suzuki T, Nagai S, Rieder G, Suzuki M, Nagai T, Fujita Y, Nagamatsu K, Ishijima N, Koyasu S, Haas R, Sasakawa C
- Journal Title
  
  Cell Hostand and Microbe 4
  
  Pages: 255-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790317
[Journal Article] The enteropathogenic E. coli-effector EspB facilitates microvilli effacing and antiphagocytosis by inhibiting myosin function2007
- Author(s)
  Iizumi, Y., Sagara H, Kabe Y, Azuma M, Kume K, Ogawa M, Nagai T, Gillespie PG, Sasakawa C, Handa H
- Journal Title
  
  Cell Host Microbe 2
  
  Pages: 383-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790317
[Presentation] Type III effectors of Enteropathogenic Escherichia coli ( EPEC) regulate the host immunity2013
- Author(s)
  Takeshi Nagai, Akio Abe, Chihiro Sasakawa, and Shigeo Koyasu
- Organizer
  第79回インターフェロンサイトカイン学会・第22回マクロファージ分子細胞生物学国際シンポジウム共催
- Place of Presentation
  東京都都市センタービル
- Data Source
  KAKENHI-PROJECT-24790423
[Presentation] Type III effectors of Enteroopathogenic Escherichia coli (EPEC) regulate the host immunity2013
- Author(s)
  Takeshi Nagai, Akio Abe, Chihiro Sasakawa, and Shigeo Koyasu
- Organizer
  第79回インターフェロンサイトカイン学会・第22回マクロファージ分子細胞生物学国際シンポジウム共催
- Place of Presentation
  都市センタービル（東京）
- Data Source
  KAKENHI-PROJECT-24790423
[Presentation] 腸管病原性大腸菌に対する宿主免疫応答の解析2010
- Author(s)
  永井武、阿部章夫、渡邉峰雄、小安重夫
- Organizer
  細菌学会関東支部インターラボセミナー
- Place of Presentation
  北里大学感染制御学府
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21790428
[Presentation] 腸管病原性大腸菌に対する宿主免疫応答の解析2010
- Author(s)
  永井武
- Organizer
  細菌学会関東支部インターラボセミナー
- Place of Presentation
  北里大学感染制御科学府2F講義室
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21790428
[Presentation] Citrobacter rodentiumの感染によって癌の転移が抑制される2008
- Author(s)
  永井武
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-19790317
[Presentation] "Citrobacter rodentiumの感染によって癌の転移が抑制される2008
- Author(s)
  永井武、三室仁美、石亀晴道、角田茂、岩倉洋一郎、笹川千尋
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19790317

Nagai Takeshi 永井 武

NAGAI Takeshi 永井 武

Research Projects

Research Products

Type III effectors of Enteroopathogenic Escherichia coli (EPEC) regulate the host immunity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the interaction between enteropathogenic Escherichia coli infection and mucosal immunity in vitro and in vivoPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the tumor metastasis inhibited by Citrobacter rodentium infection and the investigation of bacterial anti-metastasis vaccine.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「腸管出血性大腸菌感染症モデル」モデル動物使用マニュアル2012

Author(s)

Publisher

Data Source

[Book] 疾患モデル作成と利用 糖尿病・肥満・感染症2012

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Asmall-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.2011

Author(s)

Journal Title

Data Source

[Journal Article] A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] EspJ effector in enterohemorrhagic E. coli translocates into host mitochondria via an atypical mitochondrial targeting signal.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] EspJ effector in enterohemorrhagic E.coli translocates into host mitochondria via an atypical mitochondrial targeting signal.2010

Author(s)

Journal Title

Data Source

[Journal Article] Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.2009

Author(s)

Journal Title

Data Source

[Journal Article] Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses2009

Author(s)

Journal Title

Data Source

[Journal Article] Helicobacter pylori Dampens Gut Epithelial Self-Renewal by Inhibiting Apoptosis, a Bacterial Strategy to Enhance Colonization of the Stomach2007

Author(s)

Journal Title

Data Source

[Journal Article] The enteropathogenic E. coli-effector EspB facilitates microvilli effacing and antiphagocytosis by inhibiting myosin function2007

Author(s)

Journal Title

Data Source

[Presentation] Type III effectors of Enteropathogenic Escherichia coli ( EPEC) regulate the host immunity2013

Author(s)

Organizer

Place of Presentation

Data Source

Nagai Takeshi 永井武

NAGAI Takeshi 永井武

[Book] 疾患モデル作成と利用　糖尿病・肥満・感染症2012