SAITO Kan 齊藤幹

… Alternative Names

齊藤幹サイトウカン

Less

Researcher Number	60422292
Affiliation (based on the past Project Information) *help	2012: 東京大学, 医学部附属病院, 助教 2010: 東京大学, 医学部・附属病院, 助教 2008: 東京大学, 医学部・附属病, 助教 2008: 東京大学, 医学部・附属病院, 助教 2007: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Except Principal Investigator Circulatory organs internal medicine / Kidney internal medicine
Keywords	Except Principal Investigator 脂質代謝 / ラットモデル / 再灌流障害 / 体外灌流モデル / PPARγ / 線維化 / 心機能(収縮能/拡張能) / リポトキシシティ / 活性酸素 / 心機能 … More / PPARγアゴニスト / 腎障害 / 心血管障害 / 高血圧 / アンジオテンシンII / 臨床心血管病態学 / チアゾリジン / 肥満 / 遺伝子発現 / アルブミン尿 / 糖尿病 / PPARアゴニスト / PPAR アゴニスト / 蛋白尿 / 腎機能 / メタボリックシンドローム / インスリン抵抗性 / レニン・アンジオテンシン系 / リポトキシティ / 脂質 Less

Effects of PPAR-gamma agonist on lipid contents in the heart and kidney and cardiac function in hypertension/diabetes animal models
- Principal Investigator
  
  ISHIZAKA Nobukazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka Medical College
Alteration of renal lipid metabolism and its physiological importancein animal model of metabolic syndrome
- Principal Investigator
  
  ISHIZAKA Nobukazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Pioglitazone ameliorates systolic and diastolic cardiac dysfunction in rat model of angiotensin II-induced hypertension2012
- Author(s)
  Aiko Sakamoto, Makiko Hongo, Kyoko Furuta, Kan Saito, Ryozo Nagai, Nobukazu Ishizaka
- Journal Title
  
  Int J Cardiology
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22590770
[Journal Article] Reduction of renal lipid content and proteinuria by a PPAR-Y agonist in rat model of angiotensin II-induced hypertension2012
- Author(s)
  Aiko Sakamoto, Makiko Hongo, Kan Saito, Ryozo Nagai, Nobukazu Ishizaka
- Journal Title
  
  Eur J Pharmacol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22590770
[Journal Article] Liver lipid content is reduced in rat given 7-day administration of angiotensin II2011
- Author(s)
  Nobuakzu Ishizaka, Makiko Hongo, Aiko Sakamoto, Kan Saito, Kyoko Furuta, Kazhihiko Koike
- Journal Title
  
  J Renin Angiotensin Aldosterone Syst
  
  Volume: 12(4) Pages: 462-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590770
[Journal Article] Effects of the AT1 receptor blocker, losartan and calcium channel blocker, benidipine, on accumulation of lipid in the kidney of rat model of metabolic syndrome2010
- Author(s)
  Nobukazu Ishizaka, Makiko Hongo, Gen Matsuzaki, Kyoko Furuta, Kan Saito, Ryota Sakurai, Aiko Sakamoto, Kazuhiko Koike, Ryozo Nagai
- Journal Title
  
  Hypertens Res.
  
  Volume: 33(3) Pages: 263-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590770
[Journal Article] Administration of angiotensin II,but not catecholamines, inducesaccumulation of lipids in the rat heart2009
- Author(s)
  Hongo M, Ishizaka N, Furuta K, YahagiN, Saito K, Sakurai R, Matsuzaki G, Nagai R
- Journal Title
  
  Eur J Pharmacol 604(1-3)
  
  Pages: 87-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Journal Article] Comparison ofvasculoprotective effects of benidipineand losartan in a rat model of metabolic syndrome2008
- Author(s)
  Matsuzaki G, Ishizaka N, Furuta K, Hongo M, Saito K, Sakurai R, Koike K, Nagai R
- Journal Title
  
  Eur J Pharmacol 587(1-3)
  
  Pages: 237-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Journal Article] Angiotensin II-induced regulation of theexpression and localization of ironmetabolism-Related genes in the rat kidney2007
- Author(s)
  Ishizaka N, Saito K, Furuta K, MatsuzakiG, Koike K, Noiri E, Nagai R
- Journal Title
  
  Hypertension Res 30(2)
  
  Pages: 195-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Journal Article] Downregulation of klotho gene expression in streptozotocin-induced diabetic rats.2007
- Author(s)
  Nobukazu Ishizaka, Gen Matsuzaki, Kan Saito, et. al.
- Journal Title
  
  Geriatrics & Gerontology International 7
  
  Pages: 285-292
- NAID
  10020021304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Journal Article] Downregulation ofklotho gene expression in streptozotoc ininduced diabetic rats2007
- Author(s)
  Ishizaka N, Matsuzaki G, Saito K, FurutaK, Mori I, Nagai R
- Journal Title
  
  Geriatrics & Gerontology International 7(3)
  
  Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Journal Article] Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.2007
- Author(s)
  Nobukazu Ishizaka, Kan Saito, Kyoko Furuta, et. al.
- Journal Title
  
  Hypertension Research 30
  
  Pages: 195-202
- NAID
  10018831173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] 高血圧の有無とIgG4、sIL-2R値の関連について-冠動脈造影術施行症例からの検討2010
- Author(s)
  坂本愛子、齋藤幹、石坂信和、今井靖、森田啓行、永井良三
- Organizer
  第20回東京高血圧研究会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22590770
[Presentation] 糖尿病動物モデルの血管障害におけるカルシウム拮抗薬とアンジオテンシンII受容体拮抗薬の効果の比較2008
- Author(s)
  松崎弦、石坂信和、齋藤幹、本郷真紀子、桜井良太、永井良三
- Organizer
  第31回日本高血圧学会
- Place of Presentation
  札幌
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] アンジオテンシンII投与ラットの心臓における脂質集積とその生理的意義2008
- Author(s)
  本郷真紀子、石坂信和、齋藤幹、古田恭子、松崎弦、桜井良太、永井良三
- Organizer
  第31回日本高血圧学会
- Place of Presentation
  札幌
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] 2型糖尿病ラットにおけるカルシウム拮抗薬とアンジオテンシンII受容体拮抗薬の血管内皮保護作用の比較2008
- Author(s)
  石坂信和、本郷真紀子、齋藤幹、松崎弦、桜井良太、古田恭子、永井良三
- Organizer
  第49回日本脈管学会総会
- Place of Presentation
  東京
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] アンジオテンシンIIによる腎・心への脂質集積2008
- Author(s)
  本郷真紀子、石坂信和、齋藤幹、古田恭子、松崎弦、桜井良太、永井良三
- Organizer
  第9回アンジオテンシン研究会
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] アンジオテンシンIIによる血管障害への鉄キレーター治療の可能性についての検討2008
- Author(s)
  本郷真紀子、石坂信和、齋藤幹、松崎弦、桜井良太、古田恭子、永井良三
- Organizer
  第49回日本脈管学会総会
- Place of Presentation
  東京
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] PPARアゴニスト投与がアンジオテンシンII 投与ラット腎への脂質集積に与える影響の検討2008
- Author(s)
  本郷真紀子、石坂信和、齋藤幹、古田恭子、松崎弦、桜井良太、永井良三
- Organizer
  第31回日本高血圧学会
- Place of Presentation
  札幌
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] アンジオテンシンII投与ラットの心臓におけるリポトキシティ2008
- Author(s)
  本郷真紀子、石坂信和、齋藤幹、松崎弦、桜井亮太、古田恭子、永井良三
- Organizer
  第56回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Altered iron homeostasis asan underlying mechanism ofAngiotensin II-induced cardiovascular damage2007
- Author(s)
  Ishizaka N, Saito K, Furuta K, Matsuzaki G, Nagai R
- Organizer
  The Second Congress ofInternational BioIron Society (BioIron2007)
- Place of Presentation
  Kyoto
- Year and Date
  2007-04-04
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Regulation of iron metabolism-related genes in the kidney by angiotensin II.2007
- Author(s)
  Nobukazu Ishizaka, Kan Saito, Kyoko Furuta, et. al.
- Organizer
  Second Congress of International BioIron Society
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-04-05
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Angiotensin IIinduces upregulation of hemeoxygenase-1 and deposition of iron inthe kidney of rat-Possible link tooxidative stress and cellular apoptosis2007
- Author(s)
  Ishizaka N, Aizawa T, Saito K, Furuta K, Matsuzaki G, Nagai R
- Organizer
  The Second Congress of InternationalBioIron Society (BioIron 2007)
- Place of Presentation
  Kyoto
- Year and Date
  2007-04-05
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Altered iron homeostasis as an underlying mechanism of Angiotensin II-induced cardiovascular damage.2007
- Author(s)
  Nobukazu Ishizaka, Kan Saito, Kyoko Furuta, et. al.
- Organizer
  Second Congress of International BioIron Society
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-04-04
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Angiotensin II induces upregulation of heme oxygenase-1 and deposition of iron in the kidney of rat-possible linlt to oxidative stress and cellular apoptosis.2007
- Author(s)
  Nobukazu Ishizaka, Toru Aizawa, Kan Saito, et. al.
- Organizer
  Second Congress of International Biolron Society
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-04-05
- Data Source
  KAKENHI-PROJECT-19590937
[Presentation] Regulation of ironmetabolism-related genes in the kidneyby angiotensin II2007
- Author(s)
  Ishizaka N, Saito K, Furuta K, Matsuzaki G, Nagai R
- Organizer
  The Second Congressof International BioIron Society (BioIron2007)
- Place of Presentation
  Kyoto
- Year and Date
  2007-04-05
- Data Source
  KAKENHI-PROJECT-19590937

1. ISHIZAKA Nobukazu (20270879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. TSUKAMOTO Kazuhisa (20251233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NOIRI Eisei (00301820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. SEKI George (30206619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAITO Kan 齊藤 幹

齊藤 幹 サイトウ カン

Research Projects

Research Products

Co-Researchers

Effects of PPAR-gamma agonist on lipid contents in the heart and kidney and cardiac function in hypertension/diabetes animal models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alteration of renal lipid metabolism and its physiological importancein animal model of metabolic syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pioglitazone ameliorates systolic and diastolic cardiac dysfunction in rat model of angiotensin II-induced hypertension2012

Author(s)

Journal Title

Data Source

[Journal Article] Reduction of renal lipid content and proteinuria by a PPAR-Y agonist in rat model of angiotensin II-induced hypertension2012

Author(s)

Journal Title

Data Source

[Journal Article] Liver lipid content is reduced in rat given 7-day administration of angiotensin II2011

Author(s)

Journal Title

Data Source

[Journal Article] Effects of the AT1 receptor blocker, losartan and calcium channel blocker, benidipine, on accumulation of lipid in the kidney of rat model of metabolic syndrome2010

Author(s)

Journal Title

Data Source

[Journal Article] Administration of angiotensin II,but not catecholamines, inducesaccumulation of lipids in the rat heart2009

Author(s)

Journal Title

Data Source

[Journal Article] Comparison ofvasculoprotective effects of benidipineand losartan in a rat model of metabolic syndrome2008

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin II-induced regulation of theexpression and localization of ironmetabolism-Related genes in the rat kidney2007

Author(s)

Journal Title

Data Source

[Journal Article] Downregulation of klotho gene expression in streptozotocin-induced diabetic rats.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Downregulation ofklotho gene expression in streptozotoc ininduced diabetic rats2007

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.2007

Author(s)

Journal Title

NAID

Data Source

[Presentation] 高血圧の有無とIgG4、sIL-2R値の関連について-冠動脈造影術施行症例からの検討2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 糖尿病動物モデルの血管障害におけるカルシウム拮抗薬とアンジオテンシンII受容体拮抗薬の効果の比較2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] アンジオテンシンII投与ラットの心臓における脂質集積とその生理的意義2008

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 2型糖尿病ラットにおけるカルシウム拮抗薬とアンジオテンシンII受容体拮抗薬の血管内皮保護作用の比較2008

Author(s)

Organizer

SAITO Kan 齊藤幹

齊藤幹サイトウカン