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Hirai Maretoshi  平井 希俊

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HIRAI Maretoshi  平井 希俊

平井 希俊  ヒライ マレトシ

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Researcher Number 60422929
Other IDs
Affiliation (Current) 2026: 関西医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2026: 関西医科大学, 医学部, 講師
2016 – 2024: 関西医科大学, 医学部, 講師
2007: 京大, 医学(系)研究科(研究院), 助手
2006: 京都大学, 医学系研究科, 助手
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Cardiovascular medicine / Pathological medical chemistry
Keywords
Principal Investigator
心筋細胞 / 細胞周期 / ErbB受容体 / 循環器・高血圧 / ゲノム高次構造 / 核の形状 / 核のかたち / 心不全 / メカニカルストレス / ヘテロクロマチン … More / 心筋細胞増殖 / 遺伝子改変マウス / 成長因子受容体 / 心筋再生 / 細胞周期活性 / 再生医療 / ライブイメージング / ErbB / 増殖 / 発生・分化 / 再生医学 / マウス / ジーンターゲティング / ErbB2 / タンパク / 老化 / プロセッシング / DANCE / 弾性繊維 Less
  • Research Projects

    (6 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (1 People)
  •  ErbB2が制御する心筋細胞アラインメント構築機構の解明Principal Investigator

    • Principal Investigator
      平井 希俊
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kansai Medical University
  •  The role of higher-order genomic structures in cardiomyocyte nuclei under mechanical stressPrincipal Investigator

    • Principal Investigator
      平井 希俊
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kansai Medical University
  •  Elucidation of ErbB receptor signaling pathway for cardiac regenerative medicinePrincipal Investigator

    • Principal Investigator
      HIRAI Maretoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kansai Medical University
  •  Induction of proliferation of mature cardiac myocytes through ErbB receptor signalling pathwayPrincipal Investigator

    • Principal Investigator
      HIRAI Maretoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kansai Medical University
  •  ErbB受容体を介した成熟心筋細胞の増殖活性制御の分子機構Principal Investigator

    • Principal Investigator
      平井 希俊
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kansai Medical University
  •  弾性線維の形成・維持におけるDANCEプロセッシングの役割Principal Investigator

    • Principal Investigator
      平井 希俊
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress2024

    • Author(s)
      Fujiwara Keita、Inoue Tadashi、Kimoto Aya、Zixian Jiang、Tokuhiro Keizo、Yasukochi Yoshiki、Akama Tomoya O.、Cai Chen-Leng、Shiojima Ichiro、Kimura Hiroshi、Yoshimura Shige H.、Nakamura Tomoyuki、Hirai Maretoshi
    • Journal Title

      Cell Reports

      Volume: 43 Issue: 12 Pages: 115048-115048

    • DOI

      10.1016/j.celrep.2024.115048

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22H05171, KAKENHI-PUBLICLY-23H04323, KAKENHI-PROJECT-23H00369, KAKENHI-PROJECT-23K24098, KAKENHI-PROJECT-23K18226, KAKENHI-PROJECT-23K07589
  • [Journal Article] Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity2024

    • Author(s)
      Schapfl Marina A.、LoMastro Gina M.、Braun Vincent Z.、Hirai Maretoshi、Levine Michelle S.、Kiermaier Eva、Labi Verena、Holland Andrew J.、Villunger Andreas
    • Journal Title

      Nature Communications

      Volume: 15 Issue: 1

    • DOI

      10.1038/s41467-024-53222-4

    • Data Source
      KAKENHI-PROJECT-23K07589
  • [Presentation] Visualization of mechanical stress using novel tension indicators2023

    • Author(s)
      平井 希俊
    • Organizer
      日本生理学会 第100回記念大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] メカニカルストレスに対する心筋細胞核の構造的基盤を支えるヘテロクロマチンの役割2023

    • Author(s)
      平井 希俊
    • Organizer
      第101回日本生理学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07589
  • [Presentation] 心筋細胞における高次ゲノム構造のメカニカルストレスに対する核の構造的基盤としての役割2023

    • Author(s)
      平井 希俊
    • Organizer
      第46回日本分子生物学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07589
  • [Presentation] The regulation of ErbB2 expression plays an important role in formation and maintenance of cardiomyocytes alignment2022

    • Author(s)
      藤原 敬太、平井 希俊
    • Organizer
      第86回日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] 新規張力インディケーターを用いたメカニカルストレスの可視化2022

    • Author(s)
      平井 希俊
    • Organizer
      第45回分子生物学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] ゲノム高次構造は、核の恒常性・形状維持に重要な役割を果たす2022

    • Author(s)
      平井 希俊
    • Organizer
      第21回日本心臓血管発生研究会
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] ゲノム高次構造は、核の恒常性・形状維持に重要な役割を果たす2022

    • Author(s)
      平井 希俊
    • Organizer
      第45回分子生物学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] Visualization of cardiac mechanical stress using our novel tension indicator mouse2022

    • Author(s)
      藤原 敬太、平井 希俊
    • Organizer
      第86回日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] Higher-order structure of genome plays an important role in maintaining nuclear homeostasis of cardiomyocytes2022

    • Author(s)
      平井 希俊
    • Organizer
      第6回日本循環器学会基礎研究フォーラム (BCVR)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] Higher-order genomic structures play an important role in maintaining nuclear homeostasis in cardiomyocytes2022

    • Author(s)
      藤原 敬太、平井 希俊
    • Organizer
      第86回日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] 新規張力インディケーター分子およびマウスモデルの開発2021

    • Author(s)
      平井 希俊
    • Organizer
      第73回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] ErbBシグナルを介した心筋再生の可能性2020

    • Author(s)
      平井 希俊
    • Organizer
      29th Caridiovascular Metabolism and Aging Conference
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] 心臓におけるErbBシグナルの役割2020

    • Author(s)
      平井 希俊
    • Organizer
      第126回日本解剖学会総会・全国学術集会、第98回日本生理学会大会、合同大会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08502
  • [Presentation] 心臓におけるNumb, ErbB受容体による細胞周期制御2019

    • Author(s)
      平井 希俊
    • Organizer
      日本解剖学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09586
  • [Presentation] 心臓におけるNumb, ErbB受容体による細胞周期制御2019

    • Author(s)
      平井 希俊
    • Organizer
      動脈硬化Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09586
  • 1.  吉村 成弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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