Tozuka Minoru 戸塚実

… Alternative Names

TOZUKA MINORU 戸塚実

TOZUKA Minoru 戸塚実

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Researcher Number	60431954
Other IDs
Affiliation (Current)	2025: 地方独立行政法人長野県立病院機構長野県立こども病院(生命科学研究センター), 生命科学研究センター, 名誉研究員
Affiliation (based on the past Project Information) *help	2019: 信州大学, 医学部, 特任教授 2017 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2014 – 2016: 東京医科歯科大学, 大学院保健衛生学研究科, 教授 2010 – 2011: 東京医科歯科大学, 大学院・保健衛生学研究科, 教授 2009: Tokyo Medical and Dental University, 保健衛生学研究科, 教授 2007 – 2008: Tokyo Medical and Dental University, 大学院・保健衛生学研究科, 教授
Review Section/Research Field	Principal Investigator Laboratory medicine
Keywords	Principal Investigator High-density lipoprotein / コレステロール引き抜き能 / cholesterol efflux / myeloperoxidase / truncated apoAI / モノクローナル抗体 / キマーゼ / apolipoprotein A-I / HDL / 粥状硬化症 … More / 脱超遠心法 / 非放射性 / 無細胞系 / polyethylene glycol / foam cells / 冠動脈疾患 / 蛍光標識コレステロール / リポソーム結合ゲルビーズ / apolipoprotein B / コレステロール逆転送 / 心血管疾患 / ゲルビーズ / apo-B除去血清 / 高比重リポタンパク / cardiovascular disease / gel beads / apoB-depleted serum / high-density lipoprotein / SAA / apoE含有HDL / Chymase / N-ホモシステイン化 / paraoxonase1 / paraoxonase 1 / 抗炎症作用 / 抗酸化作用 / 酸化LDL / ELISA / ホモシステイン化 / 粥状動脈硬化 / carboxypeptidase A / 泡沫細胞 / Truncated apoAI / HDLサブクラス / 修飾apoAI / 抗酸化能 / apoE結合HDL / apoAI-apoAII / N-ホモシステイン化apoAI / 臨床化学 / イムノブロット法 / 粥状硬化 / バイオマーカー / ELISA法 / truncated apoA-I Less

Development of a novel cholesterol efflux assay method as neither cell culture, radioisotope nor ultracentrifugation is requiredPrincipal Investigator
- Principal Investigator
  
  Tozuka Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shinshu University
  Tokyo Medical and Dental University
Anti- and pro-atherosclerotic features of high-density lipoproteinPrincipal Investigator
- Principal Investigator
  
  TOZUKA MINORU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Development of the serum biomarkers to predict the near-term-risk for cardiovascular diseasePrincipal Investigator
- Principal Investigator
  
  TOZUKA Minoru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Development of novel biomarkers for atherosclerosisPrincipal Investigator
- Principal Investigator
  
  TOZUKA Minoru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University

All 2019 2018 2017 2016 2015 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Other

[Book] N-ホモシステイン化アポリポ蛋白A-Iの測定とその臨床的意義,検査と技術2011
- Author(s)
  戸塚実
- Data Source
  KAKENHI-PROJECT-21590611
[Journal Article] Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beads2019
- Author(s)
  Horiuchi Y, Ohkawa R, Lai SJ, Shimano S, Hagihara M, Tohda S, Kameda T, Tozuka M.
- Journal Title
  
  Bioscience Reports
  
  Volume: - Issue: 4 Pages: 1-10
- DOI
  10.1042/bsr20190213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08975, KAKENHI-PROJECT-18K15401, KAKENHI-PROJECT-17K15771
[Journal Article] Characterization of the cholesterol efflux of apolipoprotein E-containing high-density lipoprotein in THP-1 cells2019
- Author(s)
  Horiuchi Y, Ohkawa R, Lai SJ, Yamazaki A, Ikoma H, Yano K, Kameda T, Tozuka M
- Journal Title
  
  Biological Chemistry
  
  Volume: 400 Issue: 2 Pages: 209-218
- DOI
  10.1515/hsz-2018-0284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08975, KAKENHI-PROJECT-18K15401, KAKENHI-PROJECT-17K15771
[Journal Article] Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells2018
- Author(s)
  Horiuchi Y, Lai S-J, Yamazaki A, Nakamura A, Ohkawa R, Yano K, Kameda T, Okubo S, Shimano S, Hagihara M, Tohda S, Tozuka M
- Journal Title
  
  Bioscience Reports
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08975
[Journal Article] Effects of serum amyloid A on the structure and antioxidant ability of high-density lipoprotein2016
- Author(s)
  Sato M, Ohkawa R, Yoshimoto A, Yano K, Ichimura N, Nishimori M, Okubo S,. Yatomi Y, Tozuka M.
- Journal Title
  
  Bioscience Reports
  
  Volume: - Issue: 4
- DOI
  10.1042/bsr20160075
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642, KAKENHI-PROJECT-15K19174
[Journal Article] Paraoxonase 1 associated with high-density lipoprotein transfers to oxidized low-density lipoprotein depending on the degree of oxidation2016
- Author(s)
  Yoshimoto A, Ohkawa R, Yano K, Sato M, Ichimura N, Usami Y, Miyazaki A, Sugano M, Uehara T, Tozuka M
- Journal Title
  
  International Journal of Analytical Bio-Science
  
  Volume: 4 Pages: 99-109
- NAID
  40021062518
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Journal Article] Effects of myeloperoxidase-induced oxidation on antiatherogenic functions of high-density lipoprotein2015
- Author(s)
  Kameda T, Ohkawa R, Yano K, Usami Y, Miyazaki A, Matsuda K, Kawasaki K, Sugano M, Kubota T, Tozuka M
- Journal Title
  
  Journal of Lipids
  
  Volume: 2015 Pages: 1-8
- DOI
  10.1155/2015/592594
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642, KAKENHI-PROJECT-15K19174
[Journal Article] Detection of chymasedigested C-terminally truncated apolipoprotein A-I in normal human serum2011
- Author(s)
  Usami Y, Matsuda K, Sugano M, IshimineN, Kurihara Y, Sumida T, Yamauchi K, Tozuka M
- Journal Title
  
  J Immunol Methods
  
  Volume: 369 Pages: 51-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590611
[Journal Article] Identification of N-homocysteinylated apolipoprotein AI in normal human serum2010
- Author(s)
  Ishimine N, Usami Y, Nogi S, Sumida T, Kurihara Y, Matsuda K, Nakamura K, Yamauchi K, Okumura N, Tozuka M
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 47 Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590611
[Journal Article] Sialic acid moiety of apolipoprotein E3 at Thr(194) affects its interaction with beta-amyloid(1-42) peptides2008
- Author(s)
  Sugano M, Yamauchi K, Kawasaki K, Tozuka M, Fujita K, Okumura N, Ota H
- Journal Title
  
  Clin Chim Acta 388
  
  Pages: 123-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590548
[Journal Article] Plasma sphingosin-1-phosphate measurement in healthy subjects : close correlation with red blood cell parameters2008
- Author(s)
  Ohkawa R, Nakamura K, Shigeo Okubo, Hosogaya S, Ozaki Y, Tozuka M, Osima N, Yokota H, Ikeda H, Yatomi Y
- Journal Title
  
  Ann Clin Biochem 45
  
  Pages: 356-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590548
[Journal Article] In vitro expression of beta-thalassaemia gene (IVS1-1G>C) reveals complete inactivation of the normal 5' splice site and alternative aberrant RNA splicing.2007
- Author(s)
  Fujihara N, Yamauchi K, Hiro-ta-Kawadobora M, Ishikawa S, Tozuka M, et. al.
- Journal Title
  
  Annals of Clinical Biochemistry 44
  
  Pages: 573-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590548
[Journal Article] Quantitative determination of gland mucous cell-type mucin using a monoclonal antibody, HIK1083: its pathophysiological changes in human gastric juice.2007
- Author(s)
  Kubota S, Yamauchi K, Kuma-gai T, Sugano M, Kawakami K, Tozuka M, et. al.
- Journal Title
  
  Clinica Chimica Acta 377
  
  Pages: 261-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590548
[Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.2007
- Author(s)
  Nakamura K, Takeuchi T, Oh-kawa R, Okubo S, Yokota H, Tozuka M, et. al.
- Journal Title
  
  Annals of Clinical Biochemistry 44
  
  Pages: 549-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590548
[Presentation] 固相化リポソーム結合ゲルビーズを用いたコレステロール引き抜き能測定法の従来法との比較2019
- Author(s)
  堀内優奈，南部真由、賴劭睿，戸塚実，大川龍之介
- Organizer
  第66回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] HDLのコレステロール引き抜き能はHDLコレステロール濃度とは異なるバイオマーカーとなりうる2019
- Author(s)
  堀内優奈，大川龍之介，島野志都子，萩原三千男，東田修二，戸塚実
- Organizer
  第29回生物試料分析科学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] Availability of apoB-depleted serum in clinical assay for cholesterol efflux capacity using immobilized liposome-bound gel beads2019
- Author(s)
  Horiochi Y, Ohkawa R, Lai SJ, Shimano S, Hagihara M, Tohda S, Tozuka M
- Organizer
  23rd IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 血清を測定対象とする固相化リポソーム結合ゲルビーズを用いたコレステロール引き抜き能測定の検討2019
- Author(s)
  堀内優奈，賴劭睿，島野志都子，萩原三千男，東田修二，戸塚実，大川龍之介
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 新たなコレステロール引き抜き能評価法へのレシチンコレステロールアシルトランスフェラーゼの影響2019
- Author(s)
  南部真由、堀内優奈，賴劭睿，戸塚実，大川龍之介
- Organizer
  第66回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 血清アミロイドAが高比重リポタンパクのコレステロール引き抜き能に及ぼす影響2019
- Author(s)
  陸田優芽，堀内優奈，藤井祐葵，賴劭睿，戸塚実，大川龍之介
- Organizer
  第14回日本臨床検査教育学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 臨床現場で利用可能なコレステロール引き抜き能測定法の開発と評価2019
- Author(s)
  堀内優奈，賴劭睿，島野志都子，萩原三千男，東田修二，戸塚実，大川龍之介
- Organizer
  日本臨床検査自動化学会第51回大会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 無細胞系コレステロール引き抜き能評価法の開発と高比重リポタンパクサブクラスの引き抜き能の比較.2018
- Author(s)
  堀内優奈，賴劭睿，南部真由，大川龍之介，戸塚実.
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells2018
- Author(s)
  Horiuchi Y, Lai S-J, Yamazaki A, Nakamura A, Ohkawa R, Yano K, Kameda T, Okubo S, Shimano S, Hagihara M, Tohda S, Tozuka M
- Organizer
  XVIIIth International Symposium on Atherosclerosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] 固相化リポゾームを用いたコレステロール引き抜き能評価法の開発と評価2018
- Author(s)
  堀内優奈, 賴劭睿, 山崎あずさ, 中村文香, 大川龍之介, 矢野康次, 亀田貴寛, 大久保滋夫, 島野志都子, 萩原三千男, 東田修二, 戸塚実
- Organizer
  第58回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] Development of a novel method to estimate the cholesterol efflux capacity of high-density lipoprotein.2018
- Author(s)
  Tozuka M., Horiuchi Y., Lai S.J., Ohkawa R.
- Organizer
  2018 TMU Medical Laboratory Forum
- Invited
- Data Source
  KAKENHI-PROJECT-17K08975
[Presentation] コレステロール引き抜き能評価は細胞の分化・泡沫化の程度に大きく影響を受ける2017
- Author(s)
  矢野康次、大川龍之介，佐藤恵美、吉本明、市村直也，亀田貴寛，窪田哲朗，戸塚実
- Organizer
  第27回生物試料分析科学会年次学術集会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター，新潟市，新潟県
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] 赤血球はアポリポタンパクA-Iによる泡沫細胞からのコレステロール引き抜きに関与している2017
- Author(s)
  賴劭睿，大川龍之介，矢野康次、佐藤恵美、吉本明、戸塚実
- Organizer
  第27回生物試料分析科学会年次学術集会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター，新潟市，新潟県
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Oxidized low-density lipoprotein receives antioxidant enzyme paraoxonase 1 from high-density lipoprotein2016
- Author(s)
  Yoshimoto A, Ohkawa R, Sato M, Yano K, Tozuka M.
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Erythrocyte is associated with cholesterol efflux from foam cell by apolipoprotein A-I2016
- Author(s)
  Lai S-J, Ohkawa R, Yano K, Sato M, Yoshimoto A, Tozuka M.
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Impact of Erythrocyte on the cholesterol metabolism2016
- Author(s)
  Ohkawa R, Lai S-J, Yoshimoto A, Sato M, Yano K, Tozuka M.
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Effect of SAA on the antioxidant ability of HDL2016
- Author(s)
  Sato M., Ohkawa R., Yoshimoto A., Yano K., Okubo S., Yatomi Y., Tozuka M.
- Organizer
  American Association for Clinical Chemistry 2016 Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2016-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Analysis of oxidative susceptibility and fatty acid profile in apolipoprotein E-containing high-density lipoprotein2016
- Author(s)
  Ikoma H, Ohkawa R, Yoshimoto A, Yano K, Sato M, Kasama T, Tozuka M.
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] 血清アミロイドAがHDLの抗酸化能に与える影響2016
- Author(s)
  佐藤恵美，垂門碧，大川龍之介，吉本明，矢野康次，三上周子，生駒勇人，森田真麻，賴劭睿，戸塚実
- Organizer
  第26回生物試料分析化学会年次学術集会
- Place of Presentation
  沖縄コンベンションセンター、宜野湾市、沖縄県
- Year and Date
  2016-02-20
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Effect of differentiation and foam cell formation on cholesterol efflux capacity of apolipoprotein A-I2016
- Author(s)
  Yano K., Ohkawa R., Sato M., Yoshimoto A., Kubota T., Tozuka M
- Organizer
  American Association for Clinical Chemistry 2016 Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2016-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Modification of apolipoprotein A-I in high-density lipoprotein by myeloperoxidase and chymase2016
- Author(s)
  Morita M, Ohkawa R, Sato M, Yoshimoto A, Yano K, Kasama T, Tozuka M.
- Organizer
  32nd World Congress of Biomedical Laboratory Science
- Place of Presentation
  Kobe, Japan
- Year and Date
  2016-08-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Paraoxonase1 participates in antioxidant ability of HDL as a constituent protein but not its enzymatic activity2015
- Author(s)
  Yoshimoto A, Sato M, Yano K, Usami Y, Miyazaki A, Sugano M, Ohkawa R, Tozuka M
- Organizer
  EuroMedLab Paris 2015 the 21st IFCC-EFLM (European Congress of Clinical Chemistry and Laboratory Medicine)
- Place of Presentation
  Paris, France.
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] リポタンパクがヒト末梢血単核球（PBMC）のインターロイキン-1β前駆体の発現に与える影響の解析2015
- Author(s)
  亀田貴寛，伊藤さやか，宇佐美陽子，宮崎あかり，栗原由利子，大川龍之介，細萱茂実，戸塚実．
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場、岐阜市、岐阜県
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] apoE含有HDLの抗酸化能評価と定量法の構築2011
- Author(s)
  榎本真那実,山崎駿介,亀田貴寛,宇佐美陽子、宮崎あかり,栗原由利子,戸塚実
- Organizer
  第51回日本臨床化学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] N-homocysteinylation of apolipoprotein AI and its effect on antioxidant ability of HDL2011
- Author(s)
  Usami Y, Sumida T, Kurihara Y, Tozuka M
- Organizer
  2011 AACC Annual Meeting
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] N-ホモシステイン化の標的となるapolipoprotein AI分子中リジン残基の同定2011
- Author(s)
  山崎駿介,亀田貴寛,榎本真那実,宇佐美陽子,宮崎あかり,栗原由利子,戸塚実
- Organizer
  第51回日本臨床化学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] HDLの抗酸化能に及ぼすMyeloperoxidaseの影響2011
- Author(s)
  亀田貴寛,宇佐美陽子,榎本真那実,山崎駿介,宮崎あかり,栗原由利子,戸塚実
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] 健常人におけるN-ホモシステイン化apoAIの定量化の試み2010
- Author(s)
  隅田環,宇佐美陽子,榎本真那実,亀田貴寛,山崎駿介,石嶺南海,栗原由利子,戸塚実
- Organizer
  第50回日本臨床化学会年次学術集会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] 心筋梗塞患者血漿中のApoAI-AIIheterodimerの定量2010
- Author(s)
  宇佐美陽子,隅田環,亀田貴寛,栗原由利子,原口剛,磯部光章,戸塚実
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] 血中Truncated ApoAIの検出2009
- Author(s)
  宇佐美陽子,野木世莉那,隅田環,栗原由利子,松田和之,山内一由,戸塚実
- Organizer
  第56回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-21590611
[Presentation] Cathepsin DによるAmyloid β分解に及ぼすapolipoprotein E isoform の影響2007
- Author(s)
  栗原由利子、有竹智之、戸塚実
- Organizer
  第47回日本臨床化学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19590548
[Presentation] ApolipoproteinE含有HDLとParaoxonase1について
- Author(s)
  吉本　明、間宮周平、亀田貴寛、佐藤恵美、矢野康次、西坂薫子、寒河江　望、大川龍之介、戸塚　実
- Organizer
  第25回生物試料分析科学会年次学術集会
- Place of Presentation
  文京学院大学、東京
- Year and Date
  2015-02-14 – 2015-02-15
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Lipid hydroperoxides in apolipoprotein E-containing high-density lipoprotein
- Author(s)
  Mamiya S, Yoshimoto A, Sato M, Ohkawa R, Tozuka M
- Organizer
  American Association for Clinical Chemistry Annual Meeting 2014
- Place of Presentation
  シカゴ、イリノイ州、アメリカ合衆国
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] apoE含有HDLの抗酸化機能評価
- Author(s)
  間宮周平、吉本　明、亀田貴寛、大川龍之介、戸塚　実
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学、東京
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Effect of SAA on the structure and measurement method of HDL
- Author(s)
  Sato M, Ohkawa R, Kameda T, Yoshimoto A, Ohkubo S, Yatomi Y, Tozuka M
- Organizer
  American Association for Clinical Chemistry Annual Meeting 2014
- Place of Presentation
  シカゴ、イリノイ州、アメリカ合衆国
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] N-homocysteinylated apolipoprotein A-Iの機能解析
- Author(s)
  寒河江　望、宮崎あかり、吉本　明、大川龍之介、戸塚　実
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学、東京
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] MyeloperoxidaseによるHDLの酸化はapoA-Iのchymase分解を促進する
- Author(s)
  西坂薫子、亀田貴寛、大川龍之介、戸塚　実
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Effects of myeloperoxidase-modified HDL on reverse cholesterol transport and monocytic migration
- Author(s)
  Kameda T, Usami Y, Sagae N, Ohkawa R, Tozuka M
- Organizer
  American Association for Clinical Chemistry Annual Meeting 2014
- Place of Presentation
  シカゴ、イリノイ州、アメリカ合衆国
- Year and Date
  2014-07-27 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] MyeloperoxidaseとChymaseとの相互作用による高比重リポ蛋白分解産物の検討
- Author(s)
  西坂薫子、宇佐美陽子、大川龍之介、戸塚　実
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学、東京
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26460642
[Presentation] Myeloperoxidaseによる酸化がHDLの機能に及ぼす影響
- Author(s)
  亀田貴寛、宇佐美陽子、寒河江　望、佐藤恵美、大川龍之介、戸塚　実
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学、東京
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26460642
[]

1. KURIHARA Yuriko (70291341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 大川龍之介 (50420203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 38 results
3. HONDA Takayuki (80238815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISOBE Mitsuaki (80176263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Tozuka Minoru 戸塚 実

TOZUKA MINORU 戸塚 実

TOZUKA Minoru 戸塚 実

Research Projects

Research Products

Co-Researchers

Development of a novel cholesterol efflux assay method as neither cell culture, radioisotope nor ultracentrifugation is requiredPrincipal Investigator

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Anti- and pro-atherosclerotic features of high-density lipoproteinPrincipal Investigator

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Development of the serum biomarkers to predict the near-term-risk for cardiovascular diseasePrincipal Investigator

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Development of novel biomarkers for atherosclerosisPrincipal Investigator

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[Book] N-ホモシステイン化アポリポ蛋白A-Iの測定とその臨床的意義,検査と技術2011

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[Journal Article] Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beads2019

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[Journal Article] Characterization of the cholesterol efflux of apolipoprotein E-containing high-density lipoprotein in THP-1 cells2019

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[Journal Article] Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells2018

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[Journal Article] Effects of serum amyloid A on the structure and antioxidant ability of high-density lipoprotein2016

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DOI

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[Journal Article] Paraoxonase 1 associated with high-density lipoprotein transfers to oxidized low-density lipoprotein depending on the degree of oxidation2016

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NAID

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[Journal Article] Effects of myeloperoxidase-induced oxidation on antiatherogenic functions of high-density lipoprotein2015

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[Journal Article] Detection of chymasedigested C-terminally truncated apolipoprotein A-I in normal human serum2011

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[Journal Article] Identification of N-homocysteinylated apolipoprotein AI in normal human serum2010

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[Journal Article] Sialic acid moiety of apolipoprotein E3 at Thr(194) affects its interaction with beta-amyloid(1-42) peptides2008

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[Journal Article] Plasma sphingosin-1-phosphate measurement in healthy subjects : close correlation with red blood cell parameters2008

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[Journal Article] In vitro expression of beta-thalassaemia gene (IVS1-1G>C) reveals complete inactivation of the normal 5' splice site and alternative aberrant RNA splicing.2007

Author(s)

Tozuka Minoru 戸塚実

TOZUKA MINORU 戸塚実

TOZUKA Minoru 戸塚実