Hashikawa Naoya 橋川直也

… Alternative Names

HASHIKAWA Naoya 橋川直也

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Researcher Number	60434982
Other IDs
Affiliation (Current)	2025: 岡山理科大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 岡山理科大学, 理学部, 准教授 2009 – 2010: Okayama University of Science, 理学部, 講師 2007 – 2008: Okayama University of Science, 理学部, 助教
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 43020:Structural biochemistry-related Except Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator HSP / HSE / 転写 / Heat shock protein / アミロイドβ / ミスフォールディング / アミロイド / 熱ショックタンパク質 / うつ様行動 / マウス … More / 社会敗北ストレス / うつ病 / メディエーター / 遺伝子 / ストレス / oligomerization / Saccharomyces cerevisiae / heat shock element / heat shock protein / heat shock factor / HSP25 / 動脈硬化症 / 動脈硬化 / HSF … More Except Principal Investigator PTSD / Npas4 / 鼻腔内投与 / 恐怖記憶 / 転写調節因子 / エピジェネティクス / マウス / CGRP Less

Elucidation of the Epigenetic Mechanism of Fear Memory Control via the CGRP-Npas4 Pathway
- Principal Investigator
  
  Hashikawsa-Hobara Narumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Okayama University of Science
Elucidation of the mechanism of depression development focusing on protein misfolding.Principal Investigator
- Principal Investigator
  
  Hashikawa Naoya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Okayama University of Science
Relationship between mediator recruitment and transcriptional activity in the yeast heat shock protein.Principal Investigator
- Principal Investigator
  
  HASHIKAWA Naoya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Okayama University of Science
The role of HSP in arteriosclerosis and the regulation of HSP by HSF1Principal Investigator
- Principal Investigator
  
  HASHIKAWA Naoya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Okayama University of Science

All 2024 2023 2022 2021 2020 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] GRP causes anxiety via HP1γ-KLF11-MAOB pathway and dopamine in the dorsal hippocampus2024
- Author(s)
  Narumi Hashikawa-Hobara, Kyoushiro Fujiwara, Naoya Hashikawa
- Journal Title
  
  Communications Biology
  
  Volume: 322 Issue: 1
- DOI
  10.1038/s42003-024-05937-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07532
[Journal Article] Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway2022
- Author(s)
  Hashikawa-Hobara Narumi、Yoneyama Yoshikazu、Fujiwara Kyoushiro、Hashikawa Naoya
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1450-1450
- DOI
  10.1038/s41598-022-05518-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06531, KAKENHI-PROJECT-21K07532
[Journal Article] Effects from the induction of heat shock proteins in a murine model due to progression of aortic atherosclerosis2021
- Author(s)
  Hashikawa Naoya、Ido Masanobu、Morita Yuna、Hashikawa-Hobara Narumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-86601-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06531
[Journal Article] CGRP overexpression does not alter depression-like behavior in mice2021
- Author(s)
  Hashikawa-Hobara Narumi、Otsuka Ami、Okujima Chihiro、Hashikawa Naoya
- Journal Title
  
  PeerJ
  
  Volume: 9 Pages: e11720-e11720
- DOI
  10.7717/peerj.11720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06531
[Journal Article] Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice2021
- Author(s)
  Hashikawa-Hobara Narumi、Mishima Shuta、Okujima Chihiro、Shitanishi Youdai、Hashikawa Naoya
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-86556-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06531, KAKENHI-PROJECT-21K07532
[Journal Article] Oral administration of Eucommia ulmoides Oliv. leaves extract protects against atherosclerosis by improving macrophage function in ApoE knockout mice2020
- Author(s)
  Hashikawa‐Hobara Narumi、Hashikawa Naoya、Sugiman Nao、Hosoo Shingo、Hirata Tetsuya、Yamaguchi Yasuyo、Yamasaki Hiroo、Kawasaki Hiromu、Nishibe Sansei
- Journal Title
  
  Journal of Food Science
  
  Volume: 85 Issue: 11 Pages: 4018-4024
- DOI
  10.1111/1750-3841.15461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06531
[Journal Article] Role of angiontensin receptors in remodeling perivascular nerves.2010
- Author(s)
  Hobara N, Goda M, Hashikawa N, Jin X, Zamami Y, Takatori S, Kawasaki H.
- Journal Title
  
  Yakugaku Zasshi. 130(11)
  
  Pages: 1421-1425
- NAID
  130000451690
- Data Source
  KAKENHI-PROJECT-21770192
[Journal Article] Regeneration of perivascular nerve and role of angiotensin receptors.2010
- Author(s)
  Hobara N, Goda M, Yoshida N, Hashikawa N, Kawasaki H.
- Journal Title
  
  Yakugaku Zasshi. 130(9)
  
  Pages: 1189-1195
- NAID
  130000342379
- Data Source
  KAKENHI-PROJECT-21770192
[Journal Article] Role of heat shock transcription factor in Saccharomyces cerevisiaeoxidative stress response.2007
- Author(s)
  Naoya Hashikawa
- Journal Title
  
  Eukaryotic Cell 6
  
  Pages: 1373-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770154
[Journal Article] Different mechanisms are involved in the transcriptional activation by yeast heat shock transcription factor through two different types of heat shock elements2007
- Author(s)
  Hashikawa N, Yamamoto N, Sakurai H.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 10333-10340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770154
[Journal Article] Role of heat shock transcription factor in Saccharomyces cerevisiae oxidative stress response2007
- Author(s)
  Yamamoto A, Ueda J, Yamamoto N, Hashikawa N, Sakurai H.
- Journal Title
  
  Eukaryot Cell 6
  
  Pages: 1373-1379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770154
[Journal Article] Different mechanisms are involved in the transcriptional activation by yeastheat shock transcription factor through two different types of heat shockelements.2007
- Author(s)
  Naoya Hashikawa
- Journal Title
  
  The Journal of Biological Chemistry 282
  
  Pages: 10333-10340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770154
[Presentation] CGRPはMAOBをエピジェネティックに調節し不安を引き起こす2023
- Author(s)
  藤原亨志朗、橋川直也、橋川成美
- Organizer
  第147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21K07532
[Presentation] Effects of intranasal administration of CGRP on contextual fear memory2022
- Author(s)
  米山佳和、橋川成美、橋川直也、三宅里奈、森永由美
- Organizer
  第95回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K07532
[Presentation] 脳をターゲットとした抗体薬投与のための高分子物質脳内移行の解析2021
- Author(s)
  野田拓弥、足立陸、中谷柊斗、石原亜夕未宗海ナミ、橋川成美、橋川直也
- Organizer
  第15回臨床検査協議会学術大会
- Data Source
  KAKENHI-PROJECT-19K06531
[Presentation] 熱ショックタンパク質発現誘導剤のうつ病治療薬としての可能性の検討2021
- Author(s)
  足立陸　野田拓弥　中谷柊斗　日浦あみ　橋川成美　橋川直也
- Organizer
  第15回臨床検査協議会学術大会
- Data Source
  KAKENHI-PROJECT-19K06531
[Presentation] マウス腸間膜動脈血管床における血管内皮由来弛緩反応の解析2011
- Author(s)
  和家祥大、牧野堅人、藤原弘喜、橋川成美、橋川直也、高取真吾、川崎博己
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] アポE欠損マウスにおけるアンジオテンシンII2型受容体を介したNGF誘導神経慎重作用2011
- Author(s)
  橋川成美、橋川直也、由谷親夫、座間味義人、高取真吾、見尾光庸、川崎博己
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] NGF誘導の神経突起伸長におけるインスリン抵抗性の影響2011
- Author(s)
  井上祐輔、浅野勇人、橋川直也、橋川成美
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] インスリン抵抗性モデルラットにおける神経伸長作用の検討2010
- Author(s)
  井上祐輔、浅野勇人、橋川直也、橋川成美
- Organizer
  第21回霧島神経薬理フォーラム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Relation of HSPs expression and formation of atherosclerotic lesions in the aorta of ApoE-deficient mice2010
- Author(s)
  Naoya Hashikawa
- Organizer
  16^<th>World Congress of Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen Denmark
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Relation of HSPs expression and formation of atherosclerotic lesions in the aorta of ApoE-deficient mice 16^<th> World Congress of Basic and Clinical Pharmacology2010
- Author(s)
  Hashikawa N, Hobara N, Yutan C.
- Organizer
  Copenhagen Denmark
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Angiotensin 2 type 2 receptor activation modulates insulin receptor signaling pathways in adult sensory neurons 16^<th> World Congress of Basic and Clinical Pharmacology2010
- Author(s)
  Hobara N, Hashikawa N, Zamami Y, Kawasaki H.
- Organizer
  Copenhagen Denmark
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] アポE欠損マウスにおけるNGF神経軸索伸長のアンジオテンシンII2型受容体の役割2010
- Author(s)
  芳原成美、橋川直也、川崎博己
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] 神経成長因子(NGF)による上頚神経節初代培養細胞の神経伸張におけるアンジオテンシンII受容体の関与2010
- Author(s)
  橋川直也
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  グランキューブ大阪(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Effect of angiotensin II type 2 receptors on NGF-mediated neurite outgrowth in apoE knockout mice2010
- Author(s)
  Narumi Hashikawa
- Organizer
  11^<th> Southeast Asian Western Pacific Regional Meeting of Pharmacologists
- Place of Presentation
  PACIFICO YOKOHAMA
- Year and Date
  2010-03-22
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] アポE欠損マウスにおけるNGF神経軸索伸張のアンジオテンシンII 2型受容体の役割2010
- Author(s)
  橋川直也
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  グランキューブ大阪(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Clostridium perfringensのホスホリパーゼC遺伝子上流に存在する phased A-tractsの役割2009
- Author(s)
  田中千春、橋川直也、石橋広太郎、成谷宏文、片山誠一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] ApoEノックアウトマウス脊髄後根神経節におけるAT2受容体の機能的役割2009
- Author(s)
  橋川直也
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  ホテル金沢(石川)
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Effect of Angiotensin 2 type 2 receptors on calcitonin gene-related peptide(CGRP)neuritis outgrowth in ApoE deficient mice2009
- Author(s)
  橋川直也
- Organizer
  8th Cerebral vascular Biology International Conference
- Place of Presentation
  仙台エクセルホテル東急(宮城)
- Year and Date
  2009-07-01
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Relation of atherosclerosis and heat shock proteins in apoE deficient mice2009
- Author(s)
  Hashikawa N, Hobara N, Yutan C.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] ApoEノックアウトマウス脊髄後根神経節におけるAT2受容体の機能的役割2009
- Author(s)
  芳原成美、橋川直也、由谷親夫、川崎博己
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Effect of Angiotensin 2 type 2 receptors on calcitonin gene-related peptide (CGRP) neuritis outgrowth in ApoE deficient mice2009
- Author(s)
  Narumi Hobara, Naoya Hashikawa, Chikao Yutani, Hiromu Kawasaki
- Organizer
  10th International Symposium on Mechanisms of Vasodilatation
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Role of the phased A-tracts upstream the promoter of phospholipase C gene in Clostridium perfringens2009
- Author(s)
  橋川直也
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] 神経成長因子(NGF)による交感神経節初代培養細胞の神経伸張におけるアンギオテンシン2受容体の関与2009
- Author(s)
  橋川直也
- Organizer
  第48回日本薬学会中国四国支部学術大会
- Place of Presentation
  アスティとくしま(徳島)
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] 神経成長因子(NGF)による交感神経初代培養細胞の神経伸長におけるアンギオテンシンII受容体の関与2009
- Author(s)
  日野隼人、芳原成美、橋川直也、川崎博已
- Organizer
  第48回中国四国支部学術大会
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Relation of atherosclerosis and heat shock proteins in apoE deficient mice2009
- Author(s)
  橋川直也
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21770192
[Presentation] Molecular histopathological study of HSP25 and HSP72 on atherosclerotic lesions in apoliDoDrotein E deficient mice2008
- Author(s)
  Naoya Hashikawa
- Organizer
  国際病理学会(International Academy of pathology)
- Place of Presentation
  ギリシャ・アテネ
- Year and Date
  2008-10-14
- Data Source
  KAKENHI-PROJECT-19770154
[Presentation] Molecular histopathological study of HSP25 and HSP72 on atherosclerotic lesions in apolipoprotein E deficient mice2008
- Author(s)
  Taniguchi S, Hashikawa N, Murakami H, Doi, S, Kihara Y, Yamaguchi H, Imamura K, Yutani C
- Organizer
  国際病理学会(IAP)
- Place of Presentation
  ギリシャ・アテネ
- Year and Date
  2008-10-14
- Data Source
  KAKENHI-PROJECT-19770154
[Presentation] 酵母熱ショック転写因子(Hsfl)による遺伝子特異的なメディエーターのリクルートメント2008
- Author(s)
  橋川直也
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19770154

1. Hashikawsa-Hobara Narumi (30511159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 桜井博 (00225848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hashikawa Naoya 橋川 直也

HASHIKAWA Naoya 橋川 直也

Research Projects

Research Products

Co-Researchers

Elucidation of the Epigenetic Mechanism of Fear Memory Control via the CGRP-Npas4 Pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of depression development focusing on protein misfolding.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Relationship between mediator recruitment and transcriptional activity in the yeast heat shock protein.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of HSP in arteriosclerosis and the regulation of HSP by HSF1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] GRP causes anxiety via HP1γ-KLF11-MAOB pathway and dopamine in the dorsal hippocampus2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects from the induction of heat shock proteins in a murine model due to progression of aortic atherosclerosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CGRP overexpression does not alter depression-like behavior in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Npas4 impairs fear memory via phosphorylated HDAC5 induced by CGRP administration in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Eucommia ulmoides Oliv. leaves extract protects against atherosclerosis by improving macrophage function in ApoE knockout mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of angiontensin receptors in remodeling perivascular nerves.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Regeneration of perivascular nerve and role of angiotensin receptors.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Role of heat shock transcription factor in Saccharomyces cerevisiaeoxidative stress response.2007

Author(s)

Journal Title

Data Source

[Journal Article] Different mechanisms are involved in the transcriptional activation by yeast heat shock transcription factor through two different types of heat shock elements2007

Author(s)

Journal Title

Data Source

[Journal Article] Role of heat shock transcription factor in Saccharomyces cerevisiae oxidative stress response2007

Author(s)

Journal Title

Hashikawa Naoya 橋川直也

HASHIKAWA Naoya 橋川直也

[Presentation] 脳をターゲットとした抗体薬投与のための高分子物質脳内移行の解析2021