MUKAI Yohei 向洋平

… Alternative Names

MUKAI Yohe 向洋平

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Researcher Number	60444501
Other IDs	https://orcid.org/0000-0003-4288-4062
Affiliation (based on the past Project Information) *help	2014: 独立行政法人医薬基盤研究所, 創薬支援スクリーニングセンター, サブプロジェクトリーダー 2014: 独立行政法人医薬基盤研究所, サブプロジェクトリーダー 2012: 大阪大学, 大学院・薬学研究科, 助教 2008 – 2010: Osaka University, 大学院・薬学研究科, 助教 2008 – 2010: Osaka University, 薬学研究科, 助教
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Drug development chemistry / Tumor diagnosis
Keywords	Principal Investigator 医療薬剤学 / 腫瘍血管 / 抗体ライブラリ / ファージディスプレイ / 抗体医薬開発 / ミサイル療法 / ファージ表面提示法 / 細胞内侵入 / 抗体療法 / MRI / SPECT / 抗体 / 医用・生体画像 … More Except Principal Investigator … More 人工核酸 / Robo4 / 炎症 / 敗血症 / 血管内皮細胞 / 腫瘍血管特異的抗体 / SPECT / 金磁性ナノ粒子 / 癌 / MRI / PET/MRI / 腫瘍血管 / モノクローナル抗体 / イメージング Less

抗体薬物複合体の開発基盤：ヒト由来細胞内侵入抗体の迅速創製システムの構築Principal Investigator
- Principal Investigator
  
  向洋平
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  独立行政法人医薬基盤研究所
A novel anti-inflammatory strategy by targeting endothelial cell-specific receptor, Robo4
- Principal Investigator
  
  OKADA Yoshiaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University
Development of a tumor diagnosis system using novel immuno-PET/MRI probe
- Principal Investigator
  
  NAKAGAWA Shinsaku
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Osaka University
Construction of antibody-based molecular imaging techniques to analyze a development of tumor angiogenesis.Principal Investigator
- Principal Investigator
  
  MUKAI Yohei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
Creation of cell-internalizing antibody for novel tumor endothelial missile therapyPrincipal Investigator
- Principal Investigator
  
  MUKAI Yohei
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University

All 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book Patent

[Book] Structural basis for the signal transduction by TNF and TNFR2015
- Author(s)
  Nakamura T, Mukai Y, Tsutsumi Y, Yamagata Y.
- Publisher
  Protein modifications in pathogenic dysregulation of signaling (Springer)
- Data Source
  KAKENHI-PROJECT-26713007
[Book] アカデミアからの抗体医薬開発に向けて2014
- Author(s)
  向　洋平
- Total Pages
  6
- Publisher
  生命科学から創薬へのイノベーション（南山堂）
- Data Source
  KAKENHI-PROJECT-26713007
[Journal Article] Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin in lung tumors.2015
- Author(s)
  Nagano K, Imai S, Zhao X, Yamashita T, Yoshioka Y, Abe Y, Mukai Y, Kamada H, Nakagawa S, Tsutsumi Y, Tsunoda S.
- Journal Title
  
  Int J Oncol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713007
[Journal Article] Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD32015
- Author(s)
  Haruhiko Kamada, Shintaro Taki, Kazuya Nagano, Masaki Inoue, Daisuke Ando, Yohei Mukai, Kazuma Higashisaka, Yasuo Yoshioka, Yasuo Tsutsumi, Shin-ichi Tsunoda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 456 Issue: 4 Pages: 908-912
- DOI
  10.1016/j.bbrc.2014.12.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J04578, KAKENHI-PROJECT-24680093, KAKENHI-PROJECT-26713007
[Journal Article] Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2.2015
- Author(s)
  Inoue M., Tsunoda S. et al.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 128 Pages: 656-669
- DOI
  10.1242/jcs.149385
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390022, KAKENHI-PROJECT-26670061, KAKENHI-PROJECT-26713007
[Journal Article] Endothelial cell-specific expression of roundabout 4 is regulated by differential DNA methylation of the proximal promoter2014
- Author(s)
  Okada, Y., Funahashi, N., Tanaka, T., Nishiyama, Y., Yuan, L., Shirakura, K., Turjman, A. S., Kano, Y., Naruse, H., Suzuki, A., Sakai, M., Zhixia, J., Kitajima, K., Ishimoto, K., Hino, N., Kondoh, M., Mukai, Y., Nakagawa, S., Garcia-Cardena, G., Aird, W. C., Doi, T.
- Journal Title
  
  Arterioscler Thromb. Vasc. Biol.
  
  Volume: 34 Issue: 7 Pages: 1531-1538
- DOI
  10.1161/atvbaha.114.303818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670023, KAKENHI-PROJECT-25670056, KAKENHI-PROJECT-26293014, KAKENHI-PROJECT-26713007, KAKENHI-PROJECT-26870346
[Journal Article] Eph receptor A10 has a potential as a target for a prostate cancer therapy.2014
- Author(s)
  Kazuya Nagano, Takuya Yamashita, Masaki Inoue, Kazuma Higashisaka, Yasuo Yoshioka, Yasuhiro Abe, Yohei Mukai, Haruhiko Kamada, Yasuo Tsutsumi, Shin-ichi Tsunoda.
- Journal Title
  
  Biochemical Biophysical Research Communications.
  
  Volume: 450 Issue: 1 Pages: 545-549
- DOI
  10.1016/j.bbrc.2014.06.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430180, KAKENHI-PROJECT-26713007
[Journal Article] Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro.2014
- Author(s)
  Imai S, Yoshioka Y, Morishita Y, Yoshida T, Uji M, Nagano K, Mukai Y, Kamada H, Tsunoda S, Higashisaka K, Tsutsumi Y.
- Journal Title
  
  Nanoscale Res Lett.
  
  Volume: 9(1) Issue: 1 Pages: 651-651
- DOI
  10.1186/1556-276x-9-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713007
[Journal Article] Intestinal absorption and biological effects of orally administered amorphous silica particles.2014
- Author(s)
  Yoshida T., Yoshioka Y., Takahashi H., Misato K., Mori T., Hirai T., Nagano K., Abe Y., Mukai Y., Kamada H., Tsunoda S., Nabeshi H., Yoshikawa T., Higashisaka K., Tsutsumi Y.
- Journal Title
  
  Nanoscale Res Lett.
  
  Volume: 9 Issue: 1 Pages: 532-532
- DOI
  10.1186/1556-276x-9-532
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670075, KAKENHI-PROJECT-26713007
[Journal Article] Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers.2014
- Author(s)
  Kazuya Nagano, Yuka Maeda, So-ichiro Kanasaki, Takanobu Watanabe, Takuya Yamashita, Masaki Inoue, Kazuma Higashisaka, Yasuo Yoshioka, Yasuhiro Abe, Yohei Mukai, Haruhiko Kamada, Yasuo Tsutsumi, Shin-ichi Tsunoda.
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 189 Pages: 72-79
- DOI
  10.1016/j.jconrel.2014.06.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430180, KAKENHI-PROJECT-26713007
[Journal Article] Robo4 is an effective tumor endothelial marker for antibody-drug conjugates based on the rapid isolation of the anti-Robo4 cell-internalizing antibody2013
- Author(s)
  M. Yoshikawa, Y. Mukai, Y. Okada, Y. Tsumori, S. Tsunoda, Y. Tsutsumi, W. C. Aird, Y. Yoshioka, N. Okada, T. Doi, S. Nakagawa
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 14 Pages: 2804-2813
- DOI
  10.1182/blood-2012-12-468363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] がんの早期診断を目指した腫瘍ターゲティング型MRI造影剤の開発2012
- Author(s)
  向洋平他
- Journal Title
  
  磁気と健康
  
  Volume: 24 Pages: 6-10
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] がんの早期診断を目指した腫瘍ターゲティング型MRI 造影剤の開発2012
- Author(s)
  向洋平、清野智史、中川晋作
- Journal Title
  
  磁気と健康
  
  Volume: 24 Pages: 6-10
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif.2011
- Author(s)
  Yoshikawa M, Mukai Y, Tsunoda SI, Tsutsumi Y, Yoshioka Y, Okada N, Nakagawa S.
- Journal Title
  
  J Biosci Bioeng.
  
  Volume: (in press)
- NAID
  110008661211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif2011
- Author(s)
  M. Yoshikawa, Y. Mukai, SI. Tsunoda, Y. Tsutsumi, Y. Yoshioka, N. Okada, S. Nakagawa
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 111 Issue: 5 Pages: 597-599
- DOI
  10.1016/j.jbiosc.2010.12.025
- NAID
  110008661211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(12)
  
  Pages: 3357-3363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 393(4) Pages: 888-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(12)
  
  Pages: 3357-3363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 腫瘍MRイメージングにおける造影剤開発2010
- Author(s)
  向洋平、中川晋作
- Journal Title
  
  JSMI Report. 3(1)
  
  Pages: 14-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] 腫瘍標的MRI造影剤の研究開発動向2010
- Author(s)
  向洋平、中川晋作
- Journal Title
  
  PETジャーナル
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent.2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 21(6) Pages: 1026-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] 腫瘍MRイメージングにおける造影剤開発2010
- Author(s)
  向洋平、中川晋作
- Journal Title
  
  JSMI Report 3(1)
  
  Pages: 14-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent.2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 21(6) Pages: 1026-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
- Journal Title
  
  Biochem Biophys Res Commun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Solution of the Structure of the TNF-TNFR2 Complex.2010
- Author(s)
  Mukai Y, Nakamura T, Yoshikawa M, Yoshioka Y, Tsunoda S, Nakagawa S,, Yamagata Y, Tsutsumi Y
- Journal Title
  
  Sci Signal. 3(148)
  
  Pages: 83-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
- Journal Title
  
  Biochem Biophys Res Commun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Tumor-targeting CTL expressing a single-chain Fv specific for VEGFR22010
- Author(s)
  Kanagawa N, Yanagawa T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun. 394(1)
  
  Pages: 54-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Creation of lysine-deficient mutant lymphotoxin-alpha with recepor selectivity by using a phage display system.2010
- Author(s)
  Yoshioka Y, Watanabe H, Morishige T, Yao X, Ikemizu S, Nagao C, Ahmad S, Mizuguchi K, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(7)
  
  Pages: 1935-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the receptor selectivity by using a phage display system.2010
- Author(s)
  Yoshioka Y, Watanabe H, Morishige T, Yao X, Ikemizu S, Nagao C, Ahmad S, Mizuguchi K, Tsunoda SI, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials. 31(7)
  
  Pages: 1935-1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Simple PEG Conjugation of SPIO via an Au-S Bond Improves Its Tumor Targeting Potency as a Novel MR Tumor Imaging Agent.2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S,
- Journal Title
  
  Bioconjug Chem. 21(6)
  
  Pages: 1026-1031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.2010
- Author(s)
  Nomura T, Abe Y, Kamada H, Shibata H, Kayamuro H, Inoue M, Kawara T, Arita S, Furuya T, Yamashita T, Nagano K, Yoshikawa T, Yoshioka Y, Mukai Y, Nakagawa S, Taniai M, Ohta T, Serada S, Naka T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  J Control Release. (in press)
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials
  
  Volume: 31(12) Pages: 3357-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of lysine-deficient mutant lymphotoxin-alpha with receptor selectivity by using a phage display system.2010
- Author(s)
  Yoshioka Y, Watanabe H, Morishige T, Yao X, Ikemizu S, Nagao C, Ahmad S, Mizuguchi K, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials 31(7)
  
  Pages: 1935-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Creation of a lysine-deficient LIGHT mutant with the capacity for site-specific PEGylation and low affinity for a decoy receptor2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun 393(4)
  
  Pages: 888-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Comparison of the anti-tumor activity of native, secreted, and membrane-bound LIGHT in mouse tumor models.2010
- Author(s)
  Morishige T, Yoshioka Y, Tanabe A, Yao X, Mizuguchi H, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Int Immunopharmacol 10(1)
  
  Pages: 26-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.2010
- Author(s)
  Nomura T, Abe Y, Kamada H, Shibata H, Kayamuro H, Inoue M, Kawara T, Arita S, Furuya T, Yamashita T, Nagano K, Yoshikawa T, Yoshioka Y, Mukai Y, Nakagawa S, Taniai M, Ohta T, Serada S, Naka T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  J Control Release (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Tumor-targeting CTL expressing a single-chain Fv specific for VEGFR2.2010
- Author(s)
  Kanagawa N, Yanagawa T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 393(4) Pages: 888-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Structure of the TNF-TNFR2 complex : crystal structure and supra-complex on the living cell surface.2010
- Author(s)
  Mukai Y, Nakamura T, Yoshikawa M, Yoshioka Y, Tsunoda S, Nakagawa S, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  Science Signaling
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Simple PEG conjugation of SPIO via an Au-S bond improves its tumor targeting potency as a novel MR tumor imaging agent2010
- Author(s)
  H. Kojima, Y. Mukai, M. Yoshikawa, K. Kamei, T. Yoshikawa, M. Morita, T. Inubushi, TA. Yamamoto, Y. Yoshioka, N. Okada, S. Seino, S. Nakagawa
- Journal Title
  
  Bioconjug Chem
  
  Volume: 21 Issue: 6 Pages: 1026-1031
- DOI
  10.1021/bc900487p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300337
[Journal Article] Simple PEG Conjugation of SPIO via an Au-S Bond Improves Its Tumor Targeting Potency as a Novel MR Tumor Imaging Agent2010
- Author(s)
  Kojima H, Mukai Y, Yoshikawa M, Kamei K, Yoshikawa T, Morita M, Inubushi T, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Bioconjug Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] 腫瘍MRイメージングにおける造影剤開発2010
- Author(s)
  向洋平、中川晋作
- Journal Title
  
  JSMI Report 3(1)
  
  Pages: 14-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] 腫瘍MRイメージングにおける造影剤開発2010
- Author(s)
  向洋平、中川晋作
- Journal Title
  
  JSMI Report. 3(1)
  
  Pages: 14-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy2010
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Biomaterials 31(12)
  
  Pages: 3357-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice.2010
- Author(s)
  Nomura T, Abe Y, Kamada H, Shibata H, Kayamuro H, Inoue M, Kawara T, Arita S, Furuya T, Yamashita T, Nagano K, Yoshikawa T, Yoshioka Y, Mukai Y, Nakagawa S, Taniai M, Ohta T, Serada S, Naka T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  J Control Release. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Rapid isolation of intrabody candidates by using an optimized non-immune phage antibody library.2009
- Author(s)
  Nagano K, Imai S, Mukai Y, Nakagawa S, Abe Kamada H, Tsunoda S, Tsutsumi Y
- Journal Title
  
  Pharmazie. 64(4)
  
  Pages: 238-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF : useful information for designing artificial proteo-antagonists.2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  J Biochem.(表紙掲載) 146(2)
  
  Pages: 167-172
- NAID
  10026302534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF.2009
- Author(s)
  Shibata H, Yoshioka Y, Abe Y, Ohkawa A, Nomura T, Minowa K, Mukai Y, Nakagawa S, Taniai M, Ohta T, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials. 30(34)
  
  Pages: 6638-6647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Kamei K, Mukai Y Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakaeawa S
- Journal Title
  
  Biomaterials 30
  
  Pages: 1809-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] LIGHT protein suppresses tumor growth by augmentation of immune response2009
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Watanabe H, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Immunol Lett. 127(1)
  
  Pages: 33-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] LIGHT protein suppresses tumor growth by augmentation of immune response.2009
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Watanabe H, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Immunol Lett. 127(1)
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Crystallization and. preliminary X-ray analysis of the tumour necrosis factor α-tumour necrosis factor receptortype 2 complex.2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Tsunoda S, Kamada H, Nakagawa S, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  Acta Cryst. F65(Pt3)
  
  Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Crystallization and preliminary X-ray analysis of the tumour necrosis factorα-tumour necrosis factor receptor type 2 complex2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Tsunoda S, Kamada H, Nakagawa S, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  Acta Cryst F65(Pt3)
  
  Pages: 295-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  J Mol Biol. 385(4)
  
  Pages: 1221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains2009
- Author(s)
  Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials 30(19)
  
  Pages: 3318-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Rapid isolation of intrabody candidates by using an optimized non-immune phage antibody library.2009
- Author(s)
  Nagano K, Imai S, Mukai Y, Nakagawa S, Abe Y, Kamada H, Tsunoda S, Tsutsumi Y
- Journal Title
  
  Pharmazie. 64(4)
  
  Pages: 238-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Novel protein engineering strategy for creating highly receptor-selective mutant TNFs.2009
- Author(s)
  Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  Biochem Biophys Res Commun. 388(4)
  
  Pages: 667-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF : useful information for designing artificial proteo-antagonists.2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  J Biochem.(表紙掲載) 146(2)
  
  Pages: 167-172
- NAID
  10026302534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Novel protein engineering strategy for creating highly receptor-selective mutant TNFs.2009
- Author(s)
  Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  Biochem Biophys Res Commun. 388(4)
  
  Pages: 667-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Mukai Y Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y
- Journal Title
  
  J Mol Biol. 385
  
  Pages: 1221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] LIGHT Protein suppresses tumor growth by augmentation of immune response.2009
- Author(s)
  Morishige T, Yoshioka Y, Inakura H, Tanabe A, Watanabe H, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.
- Journal Title
  
  Immunol Lett. 127(1)
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Direct cell-entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Biomaterials 30(9)
  
  Pages: 1809-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains.2009
- Author(s)
  Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials. 30(19)
  
  Pages: 3318-3323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains.2009
- Author(s)
  Yoshikawa T, Sugita T, Mukai Y, Yamanada N, Nagano K, Nabeshi H, Shibata H, Yoshioka Y, Nakagawa S, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials. 30(19)
  
  Pages: 3318-3323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Direct cell-entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery.2009
- Author(s)
  Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S,
- Journal Title
  
  Biomaterials. 30(9)
  
  Pages: 1809-1814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Novel protein engineering strategy for creating highly receptor-selective mutant TNFs2009
- Author(s)
  Nomura T, Abe Y, Kamada H, Inoue M, Kawara T, Arita S, Furuya T, Yoshioka Y, Shibata H, Kayamuro H, Yamashita T, Nagano K, Yoshikawa T, Mukai Y, Nakagawa S, Taniai M, Ohta T, Tsunoda SI, Tsutsumi Y.
- Journal Title
  
  Biochem Biophys Res Commun. 388(4)
  
  Pages: 667-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural a nalysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Tariiai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yarnagata Y, Tsutsumi Y.
- Journal Title
  
  J Mol Biol 385
  
  Pages: 1221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  J Biochem. 146(2)(表紙掲載)
  
  Pages: 167-72
- NAID
  10026302534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF2009
- Author(s)
  Shibata H, Yoshioka Y, Abe Y, Ohkawa A, Nomura T, Minowa K, Mukai Y, Nakagawa S, Taniai M, Ohta T, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials 30(34)
  
  Pages: 6638-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Crystallization and preliminary X-ray analysis of the tumour necrosis factor α-tumour necrosis factor receptor tvpe 2 complex.2009
- Author(s)
  Mukai Y.Nakamura T, Yoshioka Y, Tsunoda S, Kamada H, Nakagawa S, Yamagata Y, Tsutsumi Y.
- Journal Title
  
  Acta Cryst. F65(Pt3)
  
  Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF.2009
- Author(s)
  Shibata H, Yoshioka Y, Abe Y, Ohkawa A, Nomura T, Minowa K, Mukai Y, Nakagawa S, Taniai M, Ohta T, Kamada H, Tsunoda S, Tsutsumi Y.
- Journal Title
  
  Biomaterials. 30(34)
  
  Pages: 6638-6647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Kamei K, Mukai Y, Kojima H, Yoshikawa T, Yoshikawa M, Kiyohara G, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S.
- Journal Title
  
  Biomaterials 30
  
  Pages: 1809-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker2008
- Author(s)
  Yoshikawa M, Mukai Y Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Journal Title
  
  Protein Expr Purif. 61
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker.2008
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda SI, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S.
- Journal Title
  
  Protein Expr Purif 61(1)
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790134
[Journal Article] Ligand-independent assembly of purified soluble magic roundabout (Robo4), a tumor-specific endothelial marker2008
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, NakaEawa S.
- Journal Title
  
  Protein Expr Purif. 61
  
  Pages: 78-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200017
[Patent] MRI造影剤2010
- Inventor(s)
  向洋平、清野智史、森田将史、中川貴、中川晋作
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2010-041460
- Filing Date
  2010
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] アカデミア創薬の加速を目指した抗体医薬開発ネットワーク構想2014
- Author(s)
  向洋平
- Organizer
  抗体医薬開発ネットワークキックオフミーティング
- Place of Presentation
  大阪
- Year and Date
  2014-04-18
- Invited
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] アカデミア創薬の加速を目指した抗体医薬開発NW構想2014
- Author(s)
  向洋平
- Organizer
  第27回大阪大学医工情報連携シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2014-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Preparation of Antibody modified PEG-Au/iron-oxide composite nanoparticles as MR imaging agent2012
- Author(s)
  S. Seino, M. Yoshikawa, H. Kojima, Y. Tomono, Y. Mukai,S. Nakagawa, T. Nakagawa, T. A. Yamamoto
- Organizer
  ICAUMS2012 International Comference of the Asian Union of Magnetics Societies
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 癌ターゲティング療法における腫瘍血管内皮細胞特異的な細胞内侵入抗体の有用性評価2012
- Author(s)
  柳澤有紀、向洋平、吉川舞、岡田欣晃、吉岡靖雄、角田慎一、堤康央、岡田直貴、土井健史、中川晋作
- Organizer
  第28回日本 DDS 学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 金酸化鉄ナノ粒子の技術を応用した新規 MRI 腫瘍造影剤の開発2011
- Author(s)
  伴野由季、向洋平、吉川舞、清野智史、山本孝夫、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第61回日本薬学会近畿支部大会
- Place of Presentation
  神戸学院大学
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Cell-internalizing monoclonal antibody against VEGFR2 is a potent anti-cancer agent carrier2011
- Author(s)
  Mai Yoshikawa, Yohei Mukai, Shin-ichi Tsunoda, Yasuo Tsutsumi, Yasuo Yoshioka, Naoki Okada, Shinsaku Nakagawa
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] VEGFR2に対する抗体を用いた腫瘍イメージング2011
- Author(s)
  吉川舞、向洋平、伴野由季、金井泰和、渡部浩司、角田慎一、堤康央、畑澤順、岡田直貴、中川晋作
- Organizer
  第12回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都テルサ/京都府民総合交流プラザ
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 標的分子特異的な細胞内薬物送達を目指した細胞内侵入抗体の基礎的特性評価2011
- Author(s)
  吉川舞、向洋平、堤康央、角田慎一、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第26回日本薬剤学会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 金磁性ナノ粒子を応用した新規MRI腫瘍造影剤の開発2011
- Author(s)
  伴野由季、向洋平、吉川舞、小島拓記、清野智史、山本孝夫、森田将史、犬伏俊郎、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第26回日本薬剤学会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 金酸化鉄ナノ粒子の技術を応用した新規MRI腫瘍造影剤の開発2011
- Author(s)
  伴野由季、向洋平、吉川舞、清野智史、山本孝夫、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第61回日本薬学会近畿支部大会
- Place of Presentation
  神戸学院大学
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Modifying the antigen-immunization schedule improves the variety of monoclonal antibodies obtained from immune-phage antibody libraries against HIV-1 Nef and Vif2011
- Author(s)
  Mai Yoshikawa, Yohei Mukai, Shin-ichi Tsunoda, Yasuo Tsutsumi, Yasuo Yoshioka, Naoki Okada, Shinsaku Nakagawa
- Organizer
  HUPO 2011 10th world congress
- Place of Presentation
  ジュネーブ(スイス)
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 金磁性ナノ粒子を応用した新規MRI 腫瘍造影剤の開発2011
- Author(s)
  伴野由季、向洋平、吉川舞、小島拓記、清野智史、山本孝夫、森田将史、犬伏俊郎、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第26回日本薬剤学会
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Antibody-drug conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第25回日本薬剤学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Antibody Drug Conjugate製剤の開発を目指した細胞内侵入抗体の効率的探索法2010
- Author(s)
  向洋平
- Organizer
  技術情報協会セミナー「次世代抗体医薬品開発に向けた最新研究動向」
- Place of Presentation
  東京
- Year and Date
  2010-01-25
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Antibody-drug conjugate 製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第25回日本薬剤学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Immuno-conjugate製剤における抗体の細胞内侵入活性と抗腫瘍効果の連関解析2010
- Author(s)
  吉川舞、向洋平、堤康央、角田慎一、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Immune-conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規腫瘍MRI造影剤としてのPEG化金SPIOの有用性評価2010
- Author(s)
  松尾奈緒美、向洋平、小島拓記、吉川舞、清野智史、山本孝夫、吉岡靖雄、岡田直貴、高島庄太夫、中川晋作
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Antibody Drug Conjugate製剤の開発を目指した細胞内侵入抗体の効率的探索法2010
- Author(s)
  向洋平
- Organizer
  技術情報協会セミナー「次世代抗体医薬品開発に向けた最新研究動向」
- Place of Presentation
  東京
- Year and Date
  2010-01-25
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 抗体-薬物複合体;Antibody-drug conjugateの開発に適う細胞内侵入抗体の効率的探索法2010
- Author(s)
  吉川舞、向洋平、中川晋作
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Immuno-conjugate 製剤における抗体の細胞内侵入活性と抗腫瘍効果の連関解析2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第26回日本 DDS 学会
- Place of Presentation
  大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] Immuno-conjugate製剤における抗体の細胞内侵入活性と抗腫瘍効果の連関解析2010
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22300337
[Presentation] 抗体-薬物複合体;Antibody-drug conjugateの開発に適う細胞内侵入抗体の効率的探索法2010
- Author(s)
  吉川舞、向洋平、岡田欣晃、吉岡靖雄、岡田直貴、Aird WC、土井健史、堤康央、角田慎一、中川晋作
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 金磁性複合ナノ粒子のバイオ分野への応用2009
- Author(s)
  向洋平
- Organizer
  第31回ナノバイオ磁気工学専門研究会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 金磁性複合ナノ粒子のバイオ分野への応用2009
- Author(s)
  向洋平
- Organizer
  第31回ナノバイオ磁気工学専門研究会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] immuno-conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2009
- Author(s)
  吉川舞、向洋平、久保貴、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Yohei Mukai, Hiroki Kojima, Tomoaki Yoshikawa, Kazumasa Kamei, Mai Yoshikawa, Takao A Yamamoto, Yasuo Yoshioka, Naoki Okada, Satoshi Seino, Shinsaku Nakagawa
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 生体内応用を目指したPEG化金/酸化鉄磁性複合ナノ粒子の合成2009
- Author(s)
  清野智史、山中誠之、中川貴、小島拓記、向洋平、中川晋作、山本孝夫
- Organizer
  第33回日本磁気学会学術講演会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Receptor interaction of Tumor Necrosis Factor(TNF)based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Abe Y, Nakamura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Receptor interaction of Tumor Necrosis Factor (TNF) based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Yohei Mukai, Teruya Nakamura, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinji Ikemizu, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko Yamagata, Yasuo Tsutsumi
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid (Spain)
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Mai Yoshikawa, Yohei Mukai, Yoshiaki Okada, Yasuo Yoshioka, Shin-ichi Tsunoda, Yasuo Tsutsumi, Naoki Okada, William C Aird, Takefumi Doi, Shinsaku Nakagawa
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] immuno-conjugate:製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2009
- Author(s)
  吉川舞、向洋平、久保貴、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] TNFR1選択的阻害剤の開発を目指したTNFR1選択的変異体の創製とそのレセプター結合における構造-活性相関研究2009
- Author(s)
  向洋平、柴田寛子、中村照也、吉岡靖雄、阿部康弘、野村鉄也、谷合まどか、太田恒考、池水信二、鎌田春彦、角田慎一、中川晋作、山縣ゆり子、堤康央
- Organizer
  第9回蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] High-throughput screening method of "Cell-internalizing monoclonal antibodies", potent anti-tumor drug delivery carriers2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] High-throughput screening method of "Cell-internalizing monoclonal antibodies", potent anti-tumor drug delivery carriers2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle.2009
- Author(s)
  Kojima H, Mukai Y, Kamei K, Seino S, Morita M, Inubushi T, Yoshioka Y, Okada N, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] TNFR1選択的阻害剤の開発を目指したTNFR1選択的変異体の創製とそのレセプター結合における構造-活性相関研究2009
- Author(s)
  向洋平、柴田寛子、中村照也、吉岡靖雄、阿部康弘、野村鉄也、谷合まどか、太田恒考、池水信二、鎌田春彦、角田慎一、中川晋作、山縣ゆり子、堤康央
- Organizer
  第9回蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] The development of fully active receptor selective Tumor Necrosis Factor (TNF) mutants2009
- Author(s)
  Yoshikawa M, Mukai Y, Shibata H, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Tsunoda S, Kamada H, Nakagawa S, Tsutsumi Y
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 金磁性複合ナノ粒子のバイオ分野への応用2009
- Author(s)
  向洋平
- Organizer
  第31回ナノバイオ磁気工学専門研究会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Receptor interaction of Tumor Necrosis Factor (TNF) based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Mukai Y, Nakamura T, Yoshioka Y, Abe Y, Nakamura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle.2009
- Author(s)
  Kojima H, Mukai Y, Kamei K, Seino S, Morita M, Inubushi T, Yoshioka Y, Okada N, Nakagawa S.
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle.2009
- Author(s)
  Kojima H, Mukai Y, Kamei K, Seino S, Morita M, Inubushi T, Yoshioka Y, Okada N, Nakagawa S.
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Mukai Y, Kojima H, Yoshikawa T, Kamei K, Yoshikawa M, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] The development of fully active receptor selective Tumor Necrosis Factor (TNF) mutants2009
- Author(s)
  Yoshikawa M, Mukai Y, Shibata H, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Tsunoda S, Kamada H, Nakagawa S, Tsutsumi Y
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] The development of fully active receptor selective Tumor Necrosis Factor (TNF) mutants2009
- Author(s)
  Mai Yoshikawa, Yohei Mukai, Hiroko Shibata, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shin-ichi Tsunoda, Haruhiko Kamada, Shinsaku Nakagawa, Yasuo Tsutsumi
- Organizer
  12th International TNF Conference
- Place of Presentation
  Madrid (Spain)
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 生体内応用を目指したPEG化金/酸化鉄磁性複合ナノ粒子の合成2009
- Author(s)
  清野智史、山中誠之、中川貴、小島拓記、向洋平、中川晋作、山本孝夫
- Organizer
  第33回日本磁気学会学術講演会
- Place of Presentation
  長崎大学
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 金磁性複合ナノ粒子のバイオ分野への応用2009
- Author(s)
  向洋平
- Organizer
  第31回ナノバイオ磁気工学専門研究会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 微細超常磁性酸化鉄粒子(USPIO)をコアとしたPEG化金磁性ナノ粒子の創製とそのMRI腫瘍造影剤としての有用性評価2009
- Author(s)
  小島拓記、向洋平、森田将史、犬伏俊郎、山本孝夫、吉岡靖雄、岡田直貴、清野智史、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Antibody-drug conjugateの開発に適う細胞内侵入抗体の効率的探索法2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第8回ファーマ・バイオフォーラム
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 微細超常磁性酸化鉄粒子(USPIO)をコアとしたPEG化金磁性ナノ粒子の創製とそのMRI腫瘍造影剤としての有用性評価2009
- Author(s)
  小島拓記、向洋平、森田将史、犬伏俊郎、山本孝夫、吉岡靖雄、岡田直貴、清野智史、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Design of tumor targeting magnetic resonance imaging (MRI) agent based on gold/iron-oxide composite nanoparticle2009
- Author(s)
  Hiroki Kojima, Yohei Mukai, Kazumasa Kamei, Satoshi Seino, Masashi Morita, Toshiro Inubushi, Yasuo Yoshioka, Naoki Okada, Shinsaku Nakagawa
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Mukai Y, Kojima H, Yoshikawa T, Kamei K, Yoshikawa M, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] immuno-conjugate製剤の開発に適う細胞内侵入抗体の効率的創製法の確立2009
- Author(s)
  吉川舞、向洋平、久保貴、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Ligand independent assembly of purified soluble Magic Roundabout (Robo4), a tumor-specific endothelial marker2009
- Author(s)
  Yoshikawa M, Mukai Y, Okada Y, Yoshioka Y, Tsunoda S, Tsutsumi Y, Okada N, Aird WC, Doi T, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] Antibody-drug conjugateの開発に適う細胞内侵入抗体の効率的探索法2009
- Author(s)
  吉川舞、向洋平、吉岡靖雄、岡田直貴、堤康央、角田慎一、中川晋作
- Organizer
  第8回ファーマ・バイオフォーラム
- Place of Presentation
  名古屋
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 金磁性複合ナノ粒子のバイオ・DDS分野への展開2009
- Author(s)
  向洋平
- Organizer
  第3回「ナノメディスン・アプリケーション研究会」
- Place of Presentation
  大阪
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Direct cell entry of gold/iron-oxide magnetic nanoparticles in adenovirus mediated gene delivery2009
- Author(s)
  Mukai Y, Kojima H, Yoshikawa T, Kamei K, Yoshikawa M, Yamamoto TA, Yoshioka Y, Okada N, Seino S, Nakagawa S
- Organizer
  ECCO 15 and 34th ESMO Multidisciplinary Congress
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 金磁性複合ナノ粒子のバイオ・DDS分野への展開2009
- Author(s)
  向洋平
- Organizer
  第3回「ナノメディスン・アプリケーション研究会」
- Place of Presentation
  大阪
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] STLUCTURE-FUNCTION RELATIONSHIP OF TNF BASED ON 3D STRUCTURAL ANALYSIS OF FULLY ACTIVE TNFR1-SELECTIVE TNF MUTANT2008
- Author(s)
  Yohei Mukai, Hiroko Shibata, Teruya Nakamura, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinji Ikemizu, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko Yamagata, Yasuo Tsutsumi
- Organizer
  Cytokine 2008
- Place of Presentation
  Montreal, CANADA
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] Direct Cell-entry of Gold/iron-oxide Magnetic Nanoparticles Enhanced Adenovirus Mediated Gene Expression in Adenovirus-resistant cells2008
- Author(s)
  Kamei K, Yoshikawa T, Kojima H, Seino S, Yamamoto T A, Yoshioka Y, Okada N, Mukai Y, Nakagawa S
- Organizer
  7th international conference on the scientific and clinical applications of magnetic carriers
- Place of Presentation
  Vancouver, CANADA
- Data Source
  KAKENHI-PROJECT-20790134
[Presentation] 金磁性ナノ粒子が可能とする遺伝子導入技術の確立2008
- Author(s)
  小島拓記, 向洋平, 亀井数正, 吉川友章, 吉岡靖雄, 清野智史, 山本孝夫, 岡田直貴, 中川晋作
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規腫瘍MR造影剤の開発を目指したPEG化金磁性ナノ粒子の創製2008
- Author(s)
  亀井数正, 向洋平, 小島石記, 森田将史, 犬伏俊郎, 清野智史, 山本孝夫, 吉岡靖雄, 岡田直貴, 中川晋作
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 新規MRI腫瘍造影剤を目指したPEG化金磁性ナノ粒子の創製2008
- Author(s)
  小島拓記、亀井数正、向洋平、森田将史、犬伏俊郎、清野智史、山本孝夫、吉岡靖雄、岡田直貴、中川晋作
- Organizer
  ファーマ・バイオフォーラム2008
- Place of Presentation
  東京
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] 金磁性ナノ粒子が可能とする新規遺伝子導入法2008
- Author(s)
  小島拓記、吉川友章、亀井数正、清野智史、山本孝夫、吉岡靖雄、岡田直貴、向洋平、中川晋作
- Organizer
  遺伝子・デリバリー研究会第8回夏季セミナー
- Place of Presentation
  神戸
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-20200017
[Presentation] The search for heart secretory proteins as heart disease biomarkers.
- Author(s)
  Ogura T., Mukai Y., Maeda M., Fujio Y., Sakata Y., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Tsunoda S., Tsutsumi Y.
- Organizer
  HUPO 13th Annual World Congress
- Place of Presentation
  Madrid (Spain)
- Year and Date
  2014-10-05 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Analysis of membrane protein expression patterns for cells cultured using Cancer-Tissue Originated Spheroids.
- Author(s)
  Kamada H., Taki S., Inoue M., Nagano K., Mukai Y., Yoshioka Y., Higashisaka K., Tsutsumi Y., Tsunoda S.
- Organizer
  HUPO 13th Annual World Congress
- Place of Presentation
  Madrid (Spain)
- Year and Date
  2014-10-05 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Creation of a novel non-immune phage human antibody library which consists of four stable VH-VL pairs.
- Author(s)
  Mukai Y., Ogura T., Misato K., Nagano T., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Tsunoda S., Tsutsumi Y.
- Organizer
  5th FIP Pharmaceutical Sciences World Congress (PSWC)
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Radiolabeling of anti-VEGFR antibody and gamma camera imaging in rats.
- Author(s)
  Kanai Y., Yoshikawa M., Mukai Y., Okada N., Watabe H., Shimosegawa E., Nakagawa S., Hatazawa, J.
- Organizer
  2014 SNMMI Annual Meeting
- Place of Presentation
  St. Louis (USA)
- Year and Date
  2014-06-07 – 2014-06-11
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Optimization of an immune method to shorten time for inducing high-affinity antibodies.
- Author(s)
  Mori T., Mukai Y., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Tsunoda S., Tsutsumi Y.
- Organizer
  Federation of Asian Pharmaceutical Associations Congress 2014
- Place of Presentation
  Sabah (Malaysia)
- Year and Date
  2014-10-09 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Creation of a novel non-immune phage human antibody library which consists of four stable VH-VL pairs.
- Author(s)
  Mukai Y., Ogura T., Misato K., Nagano T., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Tsunoda S., Tsutsumi Y.
- Organizer
  2014 AAPS National Biotechnology Conference
- Place of Presentation
  San Diego (USA)
- Year and Date
  2014-05-19 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] A chemical proteoimcs for searching diagnostic markers of Parkinson’s disease.
- Author(s)
  Misato K., Mukai Y., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Fujio Y., Mochizuki H., Tsunoda S., Tsutsumi Y.
- Organizer
  HUPO 13th Annual World Congress
- Place of Presentation
  Madrid (Spain)
- Year and Date
  2014-10-05 – 2014-10-08
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Expression of Annexin A4 regulates cisplatin-susceptibility in malignant mesothelioma.
- Author(s)
  Nagano K., Yamashita T., Inoue M., Higashisaka K., Yoshioka Y., Abe Y., Mukai Y., Kamada H., Tsutsumi Y., Tsunoda S.
- Organizer
  23rd European Association for Cancer Research (EACR)
- Place of Presentation
  Munich (Germany)
- Year and Date
  2014-07-05 – 2014-07-08
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Optimization of bispecific antibody targeting CD3 and EphA10 as a bio-drug candidate against breast cancer.
- Author(s)
  Taki S., Kamada H., Inoue M., Nagano K., Mukai Y., Tsutsumi Y., Tsunoda S.
- Organizer
  The 19th JFCR-ISCC: New Antitumor Agents under Development in the US, Europe and Japan
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2014-12-10 – 2014-12-11
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Structural change of biopharmaceuticals using ion mobility mass spectrometry analysis.
- Author(s)
  Kamada H., Inoue M., Nagano K., Mukai Y, Higashisaka K., Yoshioka Y., Tsutsumi Y., Tsunoda S.
- Organizer
  5th FIP Pharmaceutical Sciences World Congress (PSWC)
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Structural study on the TNF and TNFR2 complex.
- Author(s)
  Nakamura T., Mukai Y., Yoshioka Y., Tsunoda S., Yamagata Y., Tsutsumi Y.
- Organizer
  Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  Tokyo (Japan)
- Year and Date
  2015-01-23 – 2015-01-24
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Basic analysis for screening a novel bone-regenerating peptide from the phage peptide library.
- Author(s)
  Nagano T., Mukai Y., Sugamori Y., Kato G., Ohya K., Aoki K., Higashisaka K., Yoshioka Y., Nagano K., Kamada H., Tsunoda S., Tsutsumi Y.
- Organizer
  41th Annual Meeting & Exposition of the Controlled Release Society.
- Place of Presentation
  Chicago (USA)
- Year and Date
  2014-07-13 – 2014-07-16
- Data Source
  KAKENHI-PROJECT-26713007
[Presentation] Identification of Annexin A4 as cisplatin-susceptibility related protein in malignant mesothelioma.
- Author(s)
  Nagano K., Yamashita T., Inoue M., Higashisaka K., Yoshioka Y., Abe Y., Mukai Y., Kamada H., Tsutsumi Y., Tsunoda S.
- Organizer
  5th FIP Pharmaceutical Sciences World Congress (PSWC)
- Place of Presentation
  Melbourne (Australia)
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-26713007

1. SEINO Satoshi (90432517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. OKADA Yoshiaki (50444500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
3. HATAZAWA Jun (70198745)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NAKAGAWA Shinsaku (70207728)

# of Collaborated Projects: 2 results

# of Collaborated Products: 67 results
5. MORITA Masahito (30381594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. YAMAMOTO Takao (00174798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. DOI Takefumi (00211409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. INUBUSHI Toshiro (20213142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. KANAI Yasukazu (80467555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OBIKA Satoshi (80243252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HINO Nobumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. NAGANO Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. TSUNODA Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. KAMADA Haruhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. TSUTSUMI Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
16. YOSHIOKA Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MUKAI Yohei 向 洋平

MUKAI Yohe 向 洋平

Research Projects

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Co-Researchers

抗体薬物複合体の開発基盤：ヒト由来細胞内侵入抗体の迅速創製システムの構築Principal Investigator

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A novel anti-inflammatory strategy by targeting endothelial cell-specific receptor, Robo4

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Development of a tumor diagnosis system using novel immuno-PET/MRI probe

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Construction of antibody-based molecular imaging techniques to analyze a development of tumor angiogenesis.Principal Investigator

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Creation of cell-internalizing antibody for novel tumor endothelial missile therapyPrincipal Investigator

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[Book] Structural basis for the signal transduction by TNF and TNFR2015

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[Book] アカデミアからの抗体医薬開発に向けて2014

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[Journal Article] Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin in lung tumors.2015

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[Journal Article] Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD32015

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[Journal Article] Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2.2015

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[Journal Article] Endothelial cell-specific expression of roundabout 4 is regulated by differential DNA methylation of the proximal promoter2014

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[Journal Article] Eph receptor A10 has a potential as a target for a prostate cancer therapy.2014

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[Journal Article] Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro.2014

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[Journal Article] Intestinal absorption and biological effects of orally administered amorphous silica particles.2014

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[Journal Article] Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers.2014

Author(s)

MUKAI Yohei 向洋平

MUKAI Yohe 向洋平