ONO MASAHIRO 小野昌弘

… Alternative Names

Ono Masahiro 小野昌弘

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Researcher Number	60447951
Other IDs
Affiliation (Current)	2025: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任教授 2019 – 2022: 熊本大学, 国際先端医学研究機構, 客員准教授
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Complex systems Except Principal Investigator Basic Section 49060:Virology-related
Keywords	Principal Investigator T細胞分化 / 免疫学 / T細胞 / 活性化T細胞 / シンギュラリティ / 胸腺 / アポトーシス / CRISPR / 制御性T細胞 / 転写因子 … More / トランスジェネシス / 時間動態 / 転写 / Tocky / Fluorescent Timer / T cells / Transcription / 時空間動態 / ゲノム科学 / 活性化 / シンギュラリティ細胞 … More Except Principal Investigator 動物モデル / 重症化機序 / SARS-CoV-2 / 老化 / 免疫 Less

T細胞免疫老化によるSARS-CoV-2重症化機序の動物モデルを用いた解明
- Principal Investigator
  
  野村拓志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kumamoto University
T細胞アポトーシスの時間動態解析による免疫制御機構の解明Principal Investigator
- Principal Investigator
  
  小野昌弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kumamoto University
新規技術を用いたT細胞の時空間動態測定による免疫系シンギュラリティ現象解明Principal Investigator
- Principal Investigator
  
  小野昌弘
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kumamoto University
Deciphering the Mechanism of Foxp3 Expression Control in Vivo Using Transcriptional Dynamics Analysis and CRISPRPrincipal Investigator
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kumamoto University
時間免疫学と１細胞解析の融合による免疫反応におけるシンギュラリティ現象の解明Principal Investigator
- Principal Investigator
  
  小野昌弘
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kumamoto University

All 2024 2022 2020

All Journal Article

[Journal Article] Unraveling T-cell dynamics using fluorescent timer: Insights from the Tocky system2024
- Author(s)
  Ono Masahiro
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 21 Issue: Supplemental Pages: n/a
- DOI
  10.2142/biophysico.bppb-v21.s010
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07082, KAKENHI-WRAPUP-23H05421
[Journal Article] HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system2022
- Author(s)
  Tan Benjy J. Y.、Sugata Kenji、Ono Masahiro、Satou Yorifumi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 01-12
- DOI
  10.3389/fimmu.2022.991928
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08494, KAKENHI-PROJECT-20H03724, KAKENHI-PUBLICLY-21H00433, KAKENHI-PROJECT-22K20776
[Journal Article] Temporal profiling of CD4 T-cell activation and differentiation upon SARS-CoV-2 spike protein immunisation2022
- Author(s)
  Almeida-Santos Jos?、Berkachy Rita、Tye Chanidapa Adele、Hassan Jehanne、Kalfaoglu Bahire、Selkirk Murray E.、Ono Masahiro
- Journal Title
  
  bioRxiv
  
  Volume: 0 Pages: 0-0
- DOI
  10.1101/2022.07.21.500987
- Data Source
  KAKENHI-PROJECT-21K07082, KAKENHI-PUBLICLY-21H00433
[Journal Article] Single-cell level temporal profiling of tumour-reactive T cells under immune checkpoint blockade2022
- Author(s)
  Hassan Jehanne、Appleton Elizabeth、Kalfaoglu Bahire、Pedersen Malin、Almeida-Santos Jose、Kanemaru Hisashi、Irie Nobuko、Foo Shane、Reda Omnia、Tan Benjy J.Y.、Okazaki Il-mi、Okazaki Taku、Satou Yorifumi、Harrington Kevin、Melcher Alan、Ono Masahiro
- Journal Title
  
  bioRxiv
  
  Volume: 0 Pages: 0-0
- DOI
  10.1101/2022.07.19.500582
- Data Source
  KAKENHI-PROJECT-21K07082, KAKENHI-PUBLICLY-21H00433
[Journal Article] Single-Cell Transcriptome Analysis of Treg2022
- Author(s)
  Tan Benjy Jek Yang、Ono Masahiro、Satou Yorifumi
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: - Pages: 259-278
- DOI
  10.1007/978-1-0716-2647-4_17
- ISBN
  9781071626467, 9781071626474
- Data Source
  KAKENHI-PUBLICLY-21H00433, KAKENHI-PROJECT-22K20776
[Journal Article] T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis2020
- Author(s)
  Kalfaoglu B, Almeida-Santos J, Tye A C, Satou Y, Ono M
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 589380-589380
- DOI
  10.3389/fimmu.2020.589380
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03724, KAKENHI-PROJECT-18KK0230, KAKENHI-PUBLICLY-19H05426
[Journal Article] T-cell dysregulation in COVID-192020
- Author(s)
  Kalfaoglu B, Almeida-Santos J, Tye CA, Satou Y, Ono M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 538 Pages: 204-210
- DOI
  10.1016/j.bbrc.2020.10.079
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03724, KAKENHI-PROJECT-18KK0230, KAKENHI-PUBLICLY-19H05426

1. 野村拓志 (80711001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 佐藤賢文 (70402807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 菅田謙治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ONO MASAHIRO 小野 昌弘

Ono Masahiro 小野 昌弘

Research Projects

Research Products

Co-Researchers

T細胞免疫老化によるSARS-CoV-2重症化機序の動物モデルを用いた解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T細胞アポトーシスの時間動態解析による免疫制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規技術を用いたT細胞の時空間動態測定による免疫系シンギュラリティ現象解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering the Mechanism of Foxp3 Expression Control in Vivo Using Transcriptional Dynamics Analysis and CRISPRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

時間免疫学と１細胞解析の融合による免疫反応におけるシンギュラリティ現象の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Unraveling T-cell dynamics using fluorescent timer: Insights from the Tocky system2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Temporal profiling of CD4 T-cell activation and differentiation upon SARS-CoV-2 spike protein immunisation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell level temporal profiling of tumour-reactive T cells under immune checkpoint blockade2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-Cell Transcriptome Analysis of Treg2022

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T-cell dysregulation in COVID-192020

Author(s)

Journal Title

DOI

Data Source

ONO MASAHIRO 小野昌弘

Ono Masahiro 小野昌弘