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ORIHARA Kanami  折原 芳波

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Orihara Kanami  折原 芳波

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Researcher Number 60450623
Other IDs
Affiliation (Current) 2025: 東京科学大学, 生命理工学院, 准教授
Affiliation (based on the past Project Information) *help 2020 – 2023: 東京工業大学, 生命理工学院, 准教授
2017 – 2018: 早稲田大学, 理工学術院, 講師(任期付)
2014 – 2016: 早稲田大学, 高等研究所, 助教
2007 – 2008: National Research Institute for Child Health and Development, 免疫アレルギー研究部, 共同研究員
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Collagenous pathology/Allergology / Immunology / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
Eating habits
Keywords
Principal Investigator
免疫 / アレルギー / 腸内環境 / ストレス / IgA / 概日リズム / タイトジャンクション / 炎症性腸疾患 / IBD / 体内時計 … More / 時間生物学 / 腸内細菌代謝物 / ポリフェノール / 食物繊維 / 上皮バリア / 非IgE依存性アレルギー / 血便 / 細胞増殖 / サイトカイン / 細胞群 / 消化管アレルギー / 食物タンパク質誘発性胃腸炎 / リンパ球刺激試験 / 非IgE依存性食物タンパク質誘発性胃腸炎 / 好酸球性消化管疾患 / アンフィレギュリン / グルタミン酸 / IL-10 / Tr1 / Foxp3 / Th2 / 制御性T細胞 … More
Except Principal Investigator
運動 / 抗肥満 / 骨格筋 / 代謝 / 概日リズム / 概日時計 / 栄養 / 食品科学 / 生理学 / 食品 / ヒト介入試験 / サルコペニア / 食事パターン / 栄養素 / 腸内細菌多様性 / メタボリック / 農林水産物 / マウス試験 / 人介入試験 / 肥満 / 介入試験 / 健康科学 / 腸内細菌 / メタボリックシンドローム / 機能性食品 / 時間運動学 / 時間栄養学 / 体内時計 Less
  • Research Projects

    (5 results)
  • Research Products

    (44 results)
  • Co-Researchers

    (5 People)
  •  Regulating inflammatory bowel disease by controling peripheral biological clockPrincipal Investigator

    • Principal Investigator
      Orihara Kanami
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Tokyo Institute of Technology
  •  Searching for a diagnostic marker and identification of important cell groups in non-IgE mediated gastrointestinal diseasesPrincipal Investigator

    • Principal Investigator
      Orihara Kanami
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Waseda University
  •  NMDA-R刺激によって誘導される2型T細胞特異的な生存因子の探索Principal Investigator

    • Principal Investigator
      折原 芳波
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Immunology
    • Research Institution
      Waseda University
  •  Basic and applied studies of chrononutrition based on development of functional foods and nutrients

    • Principal Investigator
      shibata shigenobu
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Eating habits
    • Research Institution
      Waseda University
  •  Basic Research for a Clarification of Mechanisms and a Clinical Use to Regulate Th2 Condition by Treg SubsetPrincipal Investigator

    • Principal Investigator
      ORIHARA Kanami
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      National Research Institute for Child Health and Development

All 2024 2023 2022 2017 2016 2015 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 臨床免疫・アレルギー科2016

    • Author(s)
      折原芳波、松本健治
    • Total Pages
      5
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Journal Article] Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease2024

    • Author(s)
      Yao Du, Kanta Kusama, Koki Hama, Xinyue Chen, Yu Tahara, Susumu Kajiwara, Shigenobu Shibata, Kanami Orihara
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 5 Pages: 2494-2494

    • DOI

      10.3390/ijms25052494

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07535, KAKENHI-PROJECT-21K11606
  • [Journal Article] ene expression patterns in distinct endoscopic findings for eosinophilic gastritis in children2017

    • Author(s)
      Sato M, Shoda T, Shimizu H, Orihara K, Futamura K, Matsuda A, Yamada Y, Yoshioka T, Shimizu T, Ohya Y, Nomura I, Matsumoto K, Arai K.
    • Journal Title

      JACI In Practice

      Volume: in press

    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Journal Article] Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice.2017

    • Author(s)
      Wada M, Orihara K, Kamagata M, Hama K, Sasaki H, Haraguchi A, Miyakawa H, Nakao A, Shibata S.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 8802-8802

    • DOI

      10.1038/s41598-017-09438-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-17J10069
  • [Journal Article] Eosinophilic esophagitis versus proton pump inhibitor-responsive esophageal eosinophilia: Transcriptome analysis2017

    • Author(s)
      Shoda T, Matsuda A, Nomura I, Okada N, Orihara K, Mikami H, Ishimura N, Ishihara S, Matsumoto K, Kinoshita Y
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: - Issue: 6 Pages: 2010-2013

    • DOI

      10.1016/j.jaci.2016.11.028

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04763, KAKENHI-PROJECT-26460937, KAKENHI-PROJECT-15K20296, KAKENHI-PROJECT-16K09282, KAKENHI-PROJECT-15K19580, KAKENHI-PROJECT-16K21670, KAKENHI-PROJECT-17K11500, KAKENHI-PROJECT-17K10166
  • [Journal Article] Controlling the peripheral clock might be a new treatment strategy in allergy and immunology.2016

    • Author(s)
      Orihara K, Saito H.
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 137 Issue: 4 Pages: 1236-1237

    • DOI

      10.1016/j.jaci.2015.08.054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Journal Article] Recent advances in understanding the roles of vascular endothelial cells in allergic inflammation2016

    • Author(s)
      Shoda T, Futamura K, Orihara K, Emi-Sugie M, Saito H, Matsumoto K, Matsuda A.
    • Journal Title

      Allergol. Int.

      Volume: 65 Issue: 1 Pages: 21-29

    • DOI

      10.1016/j.alit.2015.08.001

    • NAID

      130005290335

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15377, KAKENHI-PROJECT-16K15515, KAKENHI-PROJECT-15K19580
  • [Journal Article] Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels2016

    • Author(s)
      Shoda T, Matsuda A, Arai K, Shimizu H, Morita H, Orihara K, Okada N, Narita M, Ohya Y, Saito H, Matsumoto K, Nomura I.
    • Journal Title

      J Allergy Clin Immunol.

      Volume: in press Issue: 1 Pages: 299-303

    • DOI

      10.1016/j.jaci.2015.11.042

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19580, KAKENHI-PROJECT-15K20296, KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15377, KAKENHI-PROJECT-16K15515
  • [Journal Article] NMDA Receptor Triggering Leads CD4+ T Cells Cytokine Balance Towards Type 2 Dominant2015

    • Author(s)
      Kanami Orihara, Kent T. HayGlass, Akio Matsuda, Hirohisa Saito, Kenji Matsumoto
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: 135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26893291
  • [Journal Article] Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model.2015

    • Author(s)
      Tanabe K, Kitagawa E, Wada M, Haraguchi A, Orihara K, Tahara Y, Nakao A, Shibata S.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 14424-14424

    • DOI

      10.1038/srep14424

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26670475
  • [Journal Article] Tissue remodeling by hypersecreted EGF and amphiregulin in the airway following an acute asthma attack2009

    • Author(s)
      Enomoto Y, Orihara K, et al.
    • Journal Title

      J Allergy Clin Immunol (未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] IL-33 mediates inflammatory responses in human pulmonary microvascular endothelial cells and epithelial cells2009

    • Author(s)
      Orihara K, Yagami, A, et al
    • Journal Title

      J Allergy Clin Immunol 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] TH2 cytokines potently induce an appetite-stimulating peptide, melanin-concentrating hormone, in human vascular endothelial cells2009

    • Author(s)
      Orihara K, et al
    • Journal Title

      J Allergy Clin Immunol 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Tissue remodeling by hypersecreted EGF and amphiregulin in the airway following an acute asthma attack2009

    • Author(s)
      Enomoto Y, Orihara K, et al
    • Journal Title

      J Allergy Clin Immunol 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Corticosteroid enhances TNF-α-mediated leukocyte adhesion to pulmonary microvascular endothelial cells2008

    • Author(s)
      Matsuda A, Orihara K, et. Al
    • Journal Title

      Allergy 63

      Pages: 1610-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Corticosteroid enhances TNF-α-mediated leukocyte adhesion to puhnonary microvascular endothelial cells2008

    • Author(s)
      Matsuda A, Orihara K, et. al.
    • Journal Title

      Allergy (未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Role of regulatory and proinflammatory T cell populations in allergic diseries2008

    • Author(s)
      Orihara K, et. al.
    • Journal Title

      WAO Journal 1

      Pages: 9-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Pathophysiolosical roles of microvascular alterations in pulmonary inflamminatory diseases: Possible implications of tumor necrosis factor-alpha and CXC chmokines2008

    • Author(s)
      Orihara K, Matsuda A.
    • Journal Title

      Int J Chron Obstruct Pulmon Dis. 3-4

      Pages: 619-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Pathophysiolosical roles of microvascular alterations in pulmonary inflammatory diseases: Possible implications of tumor necrosis factor-alpha and CXC chmokines2008

    • Author(s)
      Orihara K, Matsuda A
    • Journal Title

      Int J Chron Obstruct Pulmon Dis 3-4

      Pages: 619-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Role of regulatory and proinflammatory T cell populations in allergic diseases2008

    • Author(s)
      Orihara K, et. Al
    • Journal Title

      WAO Journal 1

      Pages: 9-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Circulating Foxp^3+CD4+cell number in atopic patients and healthy controls2007

    • Author(s)
      Orihara K, et. al.
    • Journal Title

      J Allergy Clin Immunol 120

      Pages: 960-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] Circulating Foxp3+CD4+ cell number in atopic patients and healthy controls2007

    • Author(s)
      Orihara K, et. Al.
    • Journal Title

      J Allergy Clin Immunol 120

      Pages: 960-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] IL-33 mediates inflammatory responses in human pulmonary microvascular endothelial cells and epithelial cells

    • Author(s)
      Orihara K, Yagami ,A, et al.
    • Journal Title

      J Allergy Clin Immunol (未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Journal Article] TH2 cytokines potently induce an appetite-stimulating peptide, melanin-concentrating hormone, in human vascular endothelial cells

    • Author(s)
      Orihara K, et al.
    • Journal Title

      J Allergy Clin Immunol (未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease2024

    • Author(s)
      Kanami Orihara, Yao Du, Kanta Kusama, Xinyue Chen, Susumu Kajiwara
    • Organizer
      日本免疫学会
    • Data Source
      KAKENHI-PROJECT-20K07535
  • [Presentation] Urolithins Regulating Circadian Rhythms in Immunity on Intestinal Epithelial Cells2023

    • Author(s)
      YAO DU、XINYUE CHEN、梶原 将、折原 芳波
    • Organizer
      日本生物時間学会
    • Data Source
      KAKENHI-PROJECT-20K07535
  • [Presentation] Regulating Peripheral Clocks to Restore Epithelial Immunity2023

    • Author(s)
      Kanami Orihara
    • Organizer
      International Drug Discovery Science and Technology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07535
  • [Presentation] Circadian Regulations in Epithelial Barrier Functions2022

    • Author(s)
      Kanami Orihara
    • Organizer
      International Conference on Chronobiology and Circadian Rhythms
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07535
  • [Presentation] Perinatal characteristics of infants with non-IgE-mediated gastrointestinal food allergy.2017

    • Author(s)
      Nomura I, Suzuki H, Motomura K, Shoda T, Morita H, Orihara K, Ohya Y, Saito H, Matsumoto K.
    • Organizer
      The 73rd Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Atlanta, GA, USA
    • Year and Date
      2017-03-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] Stool EDN levels in different clusters of non-IgE-mediated gastrointestinal food allergy.2017

    • Author(s)
      Orihara K, Nomura I, Shoda T, Suzuki H, Morita H, Matsuda A, Saito H, Matsumoto K.
    • Organizer
      The 73rd Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Atlanta, GA, USA
    • Year and Date
      2017-03-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] Distinct plasma chemokine levels in non-IgE-mediated gastrointestinal food allergy, compared with IgE-mediated food allergy.2016

    • Author(s)
      Orihara K, Nomura I, Shoda T, Morita H, Suzuki H, Matsuda A, Saito H, Matsumoto K.
    • Organizer
      The 31st Symposium of the Collegium Internationale Allergologicum
    • Place of Presentation
      Charleston, SC, USA
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] Plasma cytokine/chemokine profiles in non-IgE-mediated gastrointestinal food allergy.2016

    • Author(s)
      Orihara K, Nomura I, Shoda T, Morita H, Suzuki H, Matsuda A, Saito H, Matsumoto K.
    • Organizer
      72nd Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Los Angeles, CA, USA
    • Year and Date
      2016-03-04
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] 新生児-乳児消化管アレルギー、クラスター3における血清中TSLP、IL33の上昇2016

    • Author(s)
      野村伊知郎、正田哲雄、松田明生、鈴木啓子、折原芳波、岡田直子、森田英明、成田雅美、大矢幸弘、斎藤博久、松本健治
    • Organizer
      第65回日本アレルギー学会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] 非IgE依存性消化管アレルギー患児におけるCRP上昇には抗原特異的なIL-6産生が関与する2015

    • Author(s)
      折原芳波、野村伊知郎、正田哲雄、鈴木啓子、森田英明、松田明生、斎藤博久、松本健治
    • Organizer
      第52回日本小児アレルギー学会
    • Place of Presentation
      奈良
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] IgE非依存性消化管アレルギーの病型ごとに抗原刺激リンパ球培養上清のサイトカインプロファイルは異なる2015

    • Author(s)
      折原芳波、野村伊知郎、正田哲雄、森田英明、松田明生、斎藤博久、松本健治
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-05-26
    • Data Source
      KAKENHI-PROJECT-15K19580
  • [Presentation] IL-33 mediates inflammatory responses in human airway epithelial cells and microvascular endothelial cells2009

    • Author(s)
      Orihara K
    • Organizer
      65th Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Washington, D.C.
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] IL-33 mediates inflammatory responses in human airway epithelial cells and microvascular endothelial cells2009

    • Author(s)
      Orihara K
    • Organizer
      65th Annual Meeting of American Academy of Alergy, Asthma and Immunology
    • Place of Presentation
      Washington, D.C.
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] In Vitro Adverse Effects of Corticosteroid on TNF-α-mediated Responses by Pulmonary Microvascular Endothelial Cells2008

    • Author(s)
      Orihara K, et. Al
    • Organizer
      64th Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Philadelphia, PA, USA
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] In vitro corticosteroid treatment enhances TNF-α-mediated inflammatory reactions of pulmonary microvascular endothelial cells2008

    • Author(s)
      Orihara K
    • Organizer
      Collegium Internationale Allergologicum 27th posium
    • Place of Presentation
      Curacao
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] In vitro corticosteroid treatment enhances TNF-α-mediated inflammatory reactions of pulmonary microvascular endothelial cells2008

    • Author(s)
      Orihara K
    • Organizer
      Collegium Internationale Allergologicum 27th Symposium
    • Place of Presentation
      Curacao
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] In Vitro Adverse Effects of Corticosteroid on TNF-α-mediated Responses by Pulmonary Microvascular Endothelial Cells.2008

    • Author(s)
      OriharaK, et. al.
    • Organizer
      64th Annual Meeting of American AcademyofAll ergy, Asthma and lmmunology
    • Place of Presentation
      Philadelphia,PA,USA
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] Differences in Foxp3^+CD4^+ratio between symptomatic atopic patients and asymptomatic atopic controls with similar levels of Thl/Th2 markers.2007

    • Author(s)
      OriharaK, et. al.
    • Organizer
      20th WorldAllergyCongress
    • Place of Presentation
      Bangkok,Thailad
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] Differences in Foxp3+CD4+ ratio between symptomatic atopic patients and asymptomatic atopic controls with similar levels of Th1/Th2 markers2007

    • Author(s)
      Orihara K, et. Al
    • Organizer
      20th World Allergy Congress
    • Place of Presentation
      Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-19790704
  • [Presentation] NMDA Receptor Triggering Leads CD4+ T Cells Cytokine Balance Towards Type 2 Dominant

    • Author(s)
      Kanami Orihara, Kent T. HayGlass, Akio Matsuda, Hirohisa Saito, Kenji Matsumoto
    • Organizer
      71st Annual Meeting of American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Houston, TX, USA
    • Year and Date
      2015-02-20 – 2015-02-24
    • Data Source
      KAKENHI-PROJECT-26893291
  • 1.  shibata shigenobu (10162629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  高橋 将記 (30711189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  田原 優 (80707399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  NOOTHALAPATI Hemanth
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  木下 芳一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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