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Ishiguro Toshina  石黒 俊名 (大沼 俊名)

ORCIDConnect your ORCID iD *help
… Alternative Names

大沼俊名

Ishiguro-Oonuma Toshina  石黒 俊名

OONUMA Toshina  大沼 俊名

ONUMA Toshina  大沼 俊名

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Researcher Number 60452695
Other IDs
External Links
Affiliation (Current) 2025: 岩手大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help 2024: 岩手大学, 農学部, 准教授
2015 – 2016: 岩手大学, 農学部, 准教授
2008 – 2009: 愛媛大, 助教
2008: Ehime University, 総合科学研究支援センター, 講師
2007: Ehime University, 総合科学研究支援センター, 助教
Review Section/Research Field
Principal Investigator
Plastic surgery / Basic Section 42020:Veterinary medical science-related / Tumor biology
Except Principal Investigator
Veterinary medical science / General surgery
Keywords
Principal Investigator
血管新生阻害薬 / 血管新生 / 血管内皮細胞 / 分化誘導 / 線維芽細胞 / 休薬 / リバウンド / 腫瘍 / in vivo イメージング / VEGF阻害剤 … More / 分子標的 / VEGF / 分子標的薬 / 角膜基質 / Tie-Gfpマウス / 角膜実質 / Tie-GFPマウス … More
Except Principal Investigator
Rad51 / BRCA2 / 放射線感受性 / 乳腺腫瘍 / DNA損傷修復 / 再生医療 / 角膜 / 血管内皮細胞 / 移植・再生医療 / 幹細胞 / 線維芽細胞 / 内皮細胞 / 血管新生 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (12 People)
  •  血管新生阻害薬の休薬によって引き起こされる腫瘍リバウンド機構の解明Principal Investigator

    • Principal Investigator
      石黒 俊名 (大沼俊名)
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Iwate University
  •  Mechanism of tumor rebound after discontinuation of anti-VEGF treatmentPrincipal Investigator

    • Principal Investigator
      Ishiguro-Oonuma Toshina
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Iwate University
  •  Comparative analysis of the interaction of Rad51 recombinase and tumor suppressor BRCA2 aimed at drug development

    • Principal Investigator
      Morimatsu Masami
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Hokkaido University
  •  線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明 再生医療への応用を目指してPrincipal Investigator

    • Principal Investigator
      大沼 俊名
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Ehime University
  •  線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明Principal Investigator

    • Principal Investigator
      大沼 俊名
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Plastic surgery
    • Research Institution
      Ehime University
  •  A study on the mechanism of induction of transdifferentiation of tissue-resident fibroblasts into endothelial cells, aiming at regenerative medicine

    • Principal Investigator
      FUJIWARA Takashi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Ehime University

All 2017 2016 2015 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown2017

    • Author(s)
      Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsushita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A
    • Journal Title

      JCI Insight

      Volume: 2 Issue: 3

    • DOI

      10.1172/jci.insight.90905

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04997, KAKENHI-PROJECT-16H05155, KAKENHI-PROJECT-16J06207, KAKENHI-PROJECT-15K20260, KAKENHI-PROJECT-15K21205, KAKENHI-PROJECT-15K10865, KAKENHI-PROJECT-16K15737, KAKENHI-PROJECT-16H02457, KAKENHI-PROJECT-15K10898
  • [Journal Article] Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity2016

    • Author(s)
      Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 3 Pages: 3283-3296

    • DOI

      10.18632/oncotarget.6488

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462478, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15K07754
  • [Journal Article] Reduced canine BRCA2 expression levels in mammary gland tumors.2015

    • Author(s)
      Yoshikawa, Y., Morimatsu, M., Ochiai, K., Ishiguro-Oonuma, T., Wada, S., Orino, K. and Watanabe, K.
    • Journal Title

      BMC Vet. Res.

      Volume: 11 Issue: 1 Pages: 159-166

    • DOI

      10.1186/s12917-015-0483-9

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26450400
  • [Journal Article] Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer.2015

    • Author(s)
      Kato, Y., Ochiai, K., Michishita, M., Azakami, D., Nakahira, R., Morimatsu, M., Ishiguro-Oonuma, T., Yoshikawa, Y., Kobayashi, M., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., and Omi, T.
    • Journal Title

      The Vwterinary Journal

      Volume: 206 Issue: 2 Pages: 145-148

    • DOI

      10.1016/j.tvjl.2015.08.002

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-13J10765, KAKENHI-PROJECT-26292161
  • [Journal Article] <b>The role of IFN-γ in regulating Nfkbiz expression in epidermal </b><b>keratinocytes </b>2015

    • Author(s)
      Toshina Ishiguro-Oonuma, Kazuhiko Ochiai, Kazuyoshi Hashizume, Masami Morimatsu
    • Journal Title

      Biomed. Res.

      Volume: 36 Issue: 2 Pages: 103-107

    • DOI

      10.2220/biomedres.36.103

    • NAID

      130005065280

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26450400
  • [Journal Article] <b>Polymorphisms of canine BRCA2 BRC repeats affecting interaction with </b><b>RAD51 </b>2015

    • Author(s)
      Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Yasunaga Yoshikawa, Chihiro Udagawa, Yuiko Kato, Masami Watanabe, Makoto Bonkobara, Masami Morimatsu, Toshinori Omi
    • Journal Title

      Biomed. Res.

      Volume: 36 Issue: 2 Pages: 155-158

    • DOI

      10.2220/biomedres.36.155

    • NAID

      130005065275

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-26660243, KAKENHI-PROJECT-15H04601
  • [Journal Article] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008

    • Author(s)
      藤原 隆, 昆 和典, 樅木勝巳, 大沼俊名
    • Journal Title

      顕微鏡 43

      Pages: 90-94

    • NAID

      130007791679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Journal Article] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008

    • Author(s)
      藤原隆, 昆和典, 樅木勝巳, 大沼俊名
    • Journal Title

      顕微鏡 43

      Pages: 90-94

    • NAID

      130007791679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Journal Article] Role of NF-kB in Constitutive Expression of MAIL in Epidemal Keratinocytes2007

    • Author(s)
      Oonuma T, Morimatsu M, Ochiai K, lwanaga T, Hashizume K.
    • Journal Title

      Joumal of Veterinary Medical Science 69

      Pages: 279-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19890145
  • [Presentation] 血管新生制御因子バソヒビンのウシ子宮・胎盤における発現動態2016

    • Author(s)
      佐藤良平,石黒(大沼)俊名,高橋透,橋爪一善,木崎景一郎
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-15K21205
  • [Presentation] ウシ栄養膜・胎膜に発現するmiRNAの探索2016

    • Author(s)
      與座明祥,石黒(大沼)俊名,高橋 透,橋爪一善,木崎景一郎
    • Organizer
      第109回日本繁殖生物学会大会
    • Place of Presentation
      麻生大学(神奈川県相模原市)
    • Year and Date
      2016-09-11
    • Data Source
      KAKENHI-PROJECT-15K21205
  • [Presentation] 愛媛大学動物実験センター改修工事を経験して2016

    • Author(s)
      石黒(大沼)俊名
    • Organizer
      JCLAM Forum 第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-15K21205
  • [Presentation] ウシ栄養膜細胞系への効果的な遺伝子導入2016

    • Author(s)
      與座明祥,石黒(大沼)俊名,高橋 透,橋爪一善,木崎景一郎
    • Organizer
      第89回日本生化学会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K21205
  • [Presentation] 癌抑制遺伝子BRCA2のイントロンにおける新規サイレンサー配列の同定と転写因子の特定2015

    • Author(s)
      角本俊介、吉川泰永、森松正美、落合和彦、石黒-大沼俊名、折野宏一
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(青森県・十和田市)
    • Year and Date
      2015-09-07
    • Data Source
      KAKENHI-PROJECT-26450400
  • [Presentation] イヌ乳腺腫瘍サンプルにおけるBRCA2発現量の減少2015

    • Author(s)
      吉川泰永、森松正美、落合和彦、石黒-大沼俊名、和田成一、折野宏一
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学(青森県・十和田市)
    • Year and Date
      2015-09-07
    • Data Source
      KAKENHI-PROJECT-26450400
  • [Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008

    • Author(s)
      藤原 隆、昆 和典、樅木 勝巳、大沼 俊名
    • Organizer
      第113回日本解剖学会総会・全国学術集会シンポジウム
    • Place of Presentation
      大分大学医学部
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008

    • Author(s)
      藤原 隆, 昆 和典, 樅木勝巳, 大沼俊名
    • Organizer
      第113回日本解剖学会総会・学術集会
    • Place of Presentation
      大分大学医学部, 由布市
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] A new mechanism of angiogenesis : Incorporation of tissue-resident fibroblasts into newly formed blood vessels nd their concomitant transdifferntiation into vascular endothelialcells2008

    • Author(s)
      Fujiwara T, Kon K, Mominoki K, Oonuma T
    • Organizer
      15^<th> International Vascular Biology Meeting
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-06-03
    • Data Source
      KAKENHI-PROJECT-20791310
  • [Presentation] 血管新生における線維芽細胞の血管内皮細胞への分化転換に関する形態学的研究2008

    • Author(s)
      藤原 隆, 昆 和典, 樅木勝巳, 大沼俊名
    • Organizer
      第40回日本臨床分子形態学会総会ならびに学術集会
    • Place of Presentation
      福岡国際会議場, 福岡市
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008

    • Author(s)
      藤原隆, 昆和典, 樅木勝巳, 大沼俊名
    • Organizer
      第113回日本解剖学会総会・学術集会, シンポジウム「線維芽細胞の多様性と分化転換」
    • Place of Presentation
      大分大学医学部, 由布市
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] A new mechanism of angiogenesis by the incorporation of tissue-resident fibroblasts into newly formed blood vessels and concomitant transdifferentiation.2008

    • Author(s)
      Fujiwara T, Kon K, Mominoki K, Oonuma T.
    • Organizer
      15^<th>International Vascular Biology Meeting
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] A new mechanism of angiogenesis : Incorporation of tissue-resident fibroblasts into newly formed blood vessels and their concomitant transdifferentiation into vascular endothelial cells2008

    • Author(s)
      Fujiwara T, Kon K, Mominoki K, Oonuma T.
    • Organizer
      15^<th> International Vascular Biology Meeting
    • Place of Presentation
      Sydney, Australia
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] 血管新生における線維芽細胞の血管内皮細胞への分化転換に関する形態学的研究2008

    • Author(s)
      藤原隆, 昆和典, 樅木勝巳, 大沼俊名
    • Organizer
      第40回日本臨床分子形態学会総会ならびに学術集会, シンポジウム3「新生血管形成の基礎と臨床」
    • Place of Presentation
      福岡国際会議場, 福岡市
    • Data Source
      KAKENHI-PROJECT-18591416
  • [Presentation] 組織常在性線維芽細胞は新生血管の内皮に分化する2008

    • Author(s)
      藤原 隆、昆 和典、樅木 勝巳、大沼 俊名
    • Organizer
      第113回日本解剖学会
    • Place of Presentation
      大分大学
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19890145
  • [Presentation] DNA相同組換えタンパク質RAD51の動物種間多型が機能に及ぼす影響の解析

    • Author(s)
      落合和彦、閑野大輝、宇田川智野、呰上大吾、大沼俊名、吉川泰永、森松正美、近江俊徳
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学(北海道・札幌市)
    • Year and Date
      2014-09-09 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-26450400
  • 1.  MOMINOKI Katsumi (70304615)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 2.  KON Kazunori (40093926)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 3.  NOSE Masato (70030913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  FUJIWARA Takashi (30036496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 5.  Morimatsu Masami (70241370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  落合 和彦 (30550488)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  植木 英雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  那須 保友
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  呰上 大吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  植村 明嘉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  小椋 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  Kim Pilhan
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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