Ishiguro Toshina 石黒俊名 (大沼俊名)

… Alternative Names

大沼俊名

Ishiguro-Oonuma Toshina 石黒俊名

OONUMA Toshina 大沼俊名

ONUMA Toshina 大沼俊名

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Researcher Number	60452695
Other IDs
External Links
Affiliation (Current)	2025: 岩手大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 岩手大学, 農学部, 准教授 2015 – 2016: 岩手大学, 農学部, 准教授 2008 – 2009: 愛媛大, 助教 2008: Ehime University, 総合科学研究支援センター, 講師 2007: Ehime University, 総合科学研究支援センター, 助教
Review Section/Research Field	Principal Investigator Plastic surgery / Basic Section 42020:Veterinary medical science-related / Tumor biology Except Principal Investigator Veterinary medical science / General surgery
Keywords	Principal Investigator 血管新生阻害薬 / 血管新生 / 血管内皮細胞 / 分化誘導 / 線維芽細胞 / 休薬 / リバウンド / 腫瘍 / in vivo イメージング / VEGF阻害剤 … More / 分子標的 / VEGF / 分子標的薬 / 角膜基質 / Tie-Gfpマウス / 角膜実質 / Tie-GFPマウス … More Except Principal Investigator Rad51 / BRCA2 / 放射線感受性 / 乳腺腫瘍 / DNA損傷修復 / 再生医療 / 角膜 / 血管内皮細胞 / 移植・再生医療 / 幹細胞 / 線維芽細胞 / 内皮細胞 / 血管新生 Less

血管新生阻害薬の休薬によって引き起こされる腫瘍リバウンド機構の解明Principal Investigator
- Principal Investigator
  
  石黒俊名 (大沼俊名)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Iwate University
Mechanism of tumor rebound after discontinuation of anti-VEGF treatmentPrincipal Investigator
- Principal Investigator
  
  Ishiguro-Oonuma Toshina
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Iwate University
Comparative analysis of the interaction of Rad51 recombinase and tumor suppressor BRCA2 aimed at drug development
- Principal Investigator
  
  Morimatsu Masami
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Hokkaido University
線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明再生医療への応用を目指してPrincipal Investigator
- Principal Investigator
  
  大沼俊名
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Ehime University
線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明Principal Investigator
- Principal Investigator
  
  大沼俊名
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Plastic surgery
- Research Institution
  Ehime University
A study on the mechanism of induction of transdifferentiation of tissue-resident fibroblasts into endothelial cells, aiming at regenerative medicine
- Principal Investigator
  
  FUJIWARA Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Ehime University

All 2017 2016 2015 2008 2007 Other

All Journal Article Presentation

[Journal Article] Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown2017
- Author(s)
  Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsushita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 3
- DOI
  10.1172/jci.insight.90905
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04997, KAKENHI-PROJECT-16H05155, KAKENHI-PROJECT-16J06207, KAKENHI-PROJECT-15K20260, KAKENHI-PROJECT-15K21205, KAKENHI-PROJECT-15K10865, KAKENHI-PROJECT-16K15737, KAKENHI-PROJECT-16H02457, KAKENHI-PROJECT-15K10898
[Journal Article] Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity2016
- Author(s)
  Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 3 Pages: 3283-3296
- DOI
  10.18632/oncotarget.6488
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462478, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15K07754
[Journal Article] Reduced canine BRCA2 expression levels in mammary gland tumors.2015
- Author(s)
  Yoshikawa, Y., Morimatsu, M., Ochiai, K., Ishiguro-Oonuma, T., Wada, S., Orino, K. and Watanabe, K.
- Journal Title
  
  BMC Vet. Res.
  
  Volume: 11 Issue: 1 Pages: 159-166
- DOI
  10.1186/s12917-015-0483-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450400
[Journal Article] Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer.2015
- Author(s)
  Kato, Y., Ochiai, K., Michishita, M., Azakami, D., Nakahira, R., Morimatsu, M., Ishiguro-Oonuma, T., Yoshikawa, Y., Kobayashi, M., Bonkobara, M., Kobayashi, M., Takahashi, K., Watanabe, M., and Omi, T.
- Journal Title
  
  The Vwterinary Journal
  
  Volume: 206 Issue: 2 Pages: 145-148
- DOI
  10.1016/j.tvjl.2015.08.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07754, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15H04601, KAKENHI-PROJECT-13J10765, KAKENHI-PROJECT-26292161
[Journal Article] The role of IFN-γ in regulating Nfkbiz expression in epidermal keratinocytes 2015
- Author(s)
 Toshina Ishiguro-Oonuma, Kazuhiko Ochiai, Kazuyoshi Hashizume, Masami Morimatsu
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 2 Pages: 103-107
- DOI
 10.2220/biomedres.36.103
- NAID
 130005065280
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-26450400
[Journal Article] Polymorphisms of canine BRCA2 BRC repeats affecting interaction with RAD51 2015
- Author(s)
 Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Yasunaga Yoshikawa, Chihiro Udagawa, Yuiko Kato, Masami Watanabe, Makoto Bonkobara, Masami Morimatsu, Toshinori Omi
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 2 Pages: 155-158
- DOI
 10.2220/biomedres.36.155
- NAID
 130005065275
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-26660243, KAKENHI-PROJECT-15H04601
[Journal Article] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Journal Title
  
  顕微鏡 43
  
  Pages: 90-94
- NAID
  130007791679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591416
[Journal Article] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Journal Title
  
  顕微鏡 43
  
  Pages: 90-94
- NAID
  130007791679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591416
[Journal Article] Role of NF-kB in Constitutive Expression of MAIL in Epidemal Keratinocytes2007
- Author(s)
  Oonuma T, Morimatsu M, Ochiai K, lwanaga T, Hashizume K.
- Journal Title
  
  Joumal of Veterinary Medical Science 69
  
  Pages: 279-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890145
[Presentation] 血管新生制御因子バソヒビンのウシ子宮・胎盤における発現動態2016
- Author(s)
  佐藤良平，石黒（大沼）俊名，高橋透，橋爪一善，木崎景一郎
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K21205
[Presentation] ウシ栄養膜・胎膜に発現するmiRNAの探索2016
- Author(s)
  與座明祥，石黒（大沼）俊名，高橋　透，橋爪一善，木崎景一郎
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻生大学（神奈川県相模原市）
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-15K21205
[Presentation] 愛媛大学動物実験センター改修工事を経験して2016
- Author(s)
  石黒（大沼）俊名
- Organizer
  JCLAM Forum 第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K21205
[Presentation] ウシ栄養膜細胞系への効果的な遺伝子導入2016
- Author(s)
  與座明祥，石黒（大沼）俊名，高橋　透，橋爪一善，木崎景一郎
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K21205
[Presentation] 癌抑制遺伝子BRCA2のイントロンにおける新規サイレンサー配列の同定と転写因子の特定2015
- Author(s)
  角本俊介、吉川泰永、森松正美、落合和彦、石黒-大沼俊名、折野宏一
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（青森県・十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26450400
[Presentation] イヌ乳腺腫瘍サンプルにおけるBRCA2発現量の減少2015
- Author(s)
  吉川泰永、森松正美、落合和彦、石黒-大沼俊名、和田成一、折野宏一
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（青森県・十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26450400
[Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008
- Author(s)
  藤原隆、昆和典、樅木勝巳、大沼俊名
- Organizer
  第113回日本解剖学会総会・全国学術集会シンポジウム
- Place of Presentation
  大分大学医学部
- Data Source
  KAKENHI-PROJECT-18591416
[Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Organizer
  第113回日本解剖学会総会・学術集会
- Place of Presentation
  大分大学医学部, 由布市
- Data Source
  KAKENHI-PROJECT-18591416
[Presentation] A new mechanism of angiogenesis : Incorporation of tissue-resident fibroblasts into newly formed blood vessels nd their concomitant transdifferntiation into vascular endothelialcells2008
- Author(s)
 Fujiwara T, Kon K, Mominoki K, Oonuma T
- Organizer
 15^<th> International Vascular Biology Meeting
- Place of Presentation
 Sydney, Australia
- Year and Date
 2008-06-03
- Data Source
 KAKENHI-PROJECT-20791310
[Presentation] 血管新生における線維芽細胞の血管内皮細胞への分化転換に関する形態学的研究2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Organizer
  第40回日本臨床分子形態学会総会ならびに学術集会
- Place of Presentation
  福岡国際会議場, 福岡市
- Data Source
  KAKENHI-PROJECT-18591416
[Presentation] 組織常在性線維芽細胞は新生血管の内皮細胞に分化する2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Organizer
  第113回日本解剖学会総会・学術集会, シンポジウム「線維芽細胞の多様性と分化転換」
- Place of Presentation
  大分大学医学部, 由布市
- Data Source
  KAKENHI-PROJECT-18591416
[Presentation] A new mechanism of angiogenesis by the incorporation of tissue-resident fibroblasts into newly formed blood vessels and concomitant transdifferentiation.2008
- Author(s)
 Fujiwara T, Kon K, Mominoki K, Oonuma T.
- Organizer
 15^<th>International Vascular Biology Meeting
- Place of Presentation
 Sydney, Australia
- Data Source
 KAKENHI-PROJECT-18591416
[Presentation] A new mechanism of angiogenesis : Incorporation of tissue-resident fibroblasts into newly formed blood vessels and their concomitant transdifferentiation into vascular endothelial cells2008
- Author(s)
 Fujiwara T, Kon K, Mominoki K, Oonuma T.
- Organizer
 15^<th> International Vascular Biology Meeting
- Place of Presentation
 Sydney, Australia
- Data Source
 KAKENHI-PROJECT-18591416
[Presentation] 血管新生における線維芽細胞の血管内皮細胞への分化転換に関する形態学的研究2008
- Author(s)
  藤原隆, 昆和典, 樅木勝巳, 大沼俊名
- Organizer
  第40回日本臨床分子形態学会総会ならびに学術集会, シンポジウム3「新生血管形成の基礎と臨床」
- Place of Presentation
  福岡国際会議場, 福岡市
- Data Source
  KAKENHI-PROJECT-18591416
[Presentation] 組織常在性線維芽細胞は新生血管の内皮に分化する2008
- Author(s)
  藤原隆、昆和典、樅木勝巳、大沼俊名
- Organizer
  第113回日本解剖学会
- Place of Presentation
  大分大学
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19890145
[Presentation] DNA相同組換えタンパク質RAD51の動物種間多型が機能に及ぼす影響の解析
- Author(s)
  落合和彦、閑野大輝、宇田川智野、呰上大吾、大沼俊名、吉川泰永、森松正美、近江俊徳
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26450400

1. MOMINOKI Katsumi (70304615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. KON Kazunori (40093926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. NOSE Masato (70030913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. FUJIWARA Takashi (30036496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. Morimatsu Masami (70241370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 落合和彦 (30550488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 植木英雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 那須保友

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 呰上大吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 植村明嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 小椋祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. Kim Pilhan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishiguro Toshina 石黒 俊名 (大沼 俊名)

大沼俊名

Ishiguro-Oonuma Toshina 石黒 俊名

OONUMA Toshina 大沼 俊名

ONUMA Toshina 大沼 俊名

Research Projects

Research Products

Co-Researchers

血管新生阻害薬の休薬によって引き起こされる腫瘍リバウンド機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of tumor rebound after discontinuation of anti-VEGF treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comparative analysis of the interaction of Rad51 recombinase and tumor suppressor BRCA2 aimed at drug development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明 再生医療への応用を目指してPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the mechanism of induction of transdifferentiation of tissue-resident fibroblasts into endothelial cells, aiming at regenerative medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduced canine BRCA2 expression levels in mammary gland tumors.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular cloning of canine co-chaperone small glutamine-rich tetratricopeptide repeat-containing protein α (SGTA) and investigation of its ability to suppress androgen receptor signalling in androgen-independent prostate cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <b>The role of IFN-γ in regulating Nfkbiz expression in epidermal </b><b>keratinocytes </b>2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] <b>Polymorphisms of canine BRCA2 BRC repeats affecting interaction with </b><b>RAD51 </b>2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

Ishiguro Toshina 石黒俊名 (大沼俊名)

Ishiguro-Oonuma Toshina 石黒俊名

OONUMA Toshina 大沼俊名

ONUMA Toshina 大沼俊名

線維芽細胞の血管内皮細胞への分化誘導メカニズムの解明再生医療への応用を目指してPrincipal Investigator