Inoue Jun 井上淳

… Alternative Names

INOUE Jun 井上淳

JUN Inoue 井上淳

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Researcher Number	60455821
Other IDs
Affiliation (Current)	2025: 東北大学, 高度教養教育・学生支援機構, 准教授 2025: 東北大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北大学, 大学病院, 講師 2019 – 2022: 東北大学, 大学病院, 助教 2014 – 2017: 東北大学, 大学病院, 助教 2008 – 2011: Tohoku University, 病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator HBV / ウイルス性肝炎 / Rabタンパク質 / Rab5B / 肝臓学 / HCC / 自然免疫 / MxB / ミトコンドリア / B型肝炎ウイルス … More / B型慢性肝炎 / CD63 / 小胞輸送 / 生活環 / Rab / 肝臟学 … More Except Principal Investigator NASH / NAFLD / 肝星細胞 / 肝細胞 / ChREBP / 非アルコール性脂肪性肝炎 / 酸化ストレス / 遊離アミノ酸 / 非アルコール性脂肪性肝疾患 / VLDL / アミノ酸 Less

新規ChREBP阻害薬の標的遺伝子に対するPerturbシークエンスを用いたNAFLDの病態制御
- Principal Investigator
  
  菅原明
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Tohoku University
ミトコンドリアを介する自然免疫応答を標的としたB型肝炎ウイルスの制御と肝発癌抑制Principal Investigator
- Principal Investigator
  
  井上淳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Impact of free amino acids on intracellular stress response mechanisms in hepatic steatosis.
- Principal Investigator
  
  Kakazu Eiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Mechanistic analysis of hepatitis B virus infection focusing on vesicle trafficking system and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Inoue Jun
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Analysis of vesicle trafficking pathways utilized for the life cycle of hepatitis B virus and its application for therapiesPrincipal Investigator
- Principal Investigator
  
  INOUE Jun
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
B型肝炎ウイルスの生活環に必要な小胞輸送の分子スイッチの解明Principal Investigator
- Principal Investigator
  
  井上淳
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Comprehensive study of hepatitis B virus genotypes and mutations involved in the pathogenesisPrincipal Investigator
- Principal Investigator
  
  INOUE Jun
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Analysis of the mechanism of fulminant hepatitis using a hepatitisB virus strain obtained from a patient in fulminant hepatitis outbreakPrincipal Investigator
- Principal Investigator
  
  JUN Inoue
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University

[Book] 肝胆膵 Vol.71 No.6 Dec.　特集　肝炎ウイルス A to E2015
- Author(s)
  井上　淳，下瀬川　徹
- Total Pages
  378
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-15K08981
[Journal Article] Usefulness of the Fibrosis‐4 index and alanine aminotransferase at 1 year of nucleos(t)ide analog treatment for prediction of hepatocellular carcinoma in chronic hepatitis B patients2024
- Author(s)
  Inoue Jun、Akahane Takehiro、Kobayashi Tomoo、Kimura Osamu、Sato Kosuke、Ninomiya Masashi、Iwata Tomoaki、Takai Satoshi、Kisara Norihiro、Sato Toshihiro、Nagasaki Futoshi、Miura Masahito、Nakamura Takuya、Umetsu Teruyuki、Sano Akitoshi、Tsuruoka Mio、Onuki Masazumi、Sawahashi Satoko、Niitsuma Hirofumi、Masamune Atsushi
- Journal Title
  
  Hepatology Research
  
  Volume: 54 Issue: 2 Pages: 131-141
- DOI
  10.1111/hepr.13957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07390
[Journal Article] Effects of sodium glucose cotransporter 2 inhibitors and pioglitazone on FIB‐4 index in metabolic‐associated fatty liver disease2023
- Author(s)
  Mino Masaaki、Kakazu Eiji、Sano Akitoshi、Katsuyama Hisayuki、Hakoshima Mariko、Yanai Hidekatsu、Aoki Yoshihiko、Imamura Masatoshi、Yamazoe Taiji、Mori Taizo、Yoshio Sachiyo、Inoue Jun、Masamune Atsushi、Kanto Tatsuya
- Journal Title
  
  Hepatology Research
  
  Volume: - Issue: 7 Pages: 618-628
- DOI
  10.1111/hepr.13898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17038, KAKENHI-PROJECT-20K08322, KAKENHI-PROJECT-21K07904
[Journal Article] The Exosome‐Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus2021
- Author(s)
  Ninomiya M, Inoue J, Krueger EW, Chen J, Cao H, Masamune A, McNiven MA
- Journal Title
  
  Hepatology Communications
  
  Volume: - Issue: 7 Pages: 1238-1251
- DOI
  10.1002/hep4.1709
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08385
[Journal Article] Steatotic hepatocytes release mature VLDL via methionine and tyrosine metabolism in a Keap1‐Nrf2 dependent manner2021
- Author(s)
  Sano Akitoshi、Kakazu Eiji、Hamada Shin、Inoue Jun、Ninomiya Masashi、Iwata Tomoaki、Tsuruoka Mio、Sato Kosuke、Masamune Atsushi
- Journal Title
  
  Hepatology
  
  Volume: - Issue: 3 Pages: 1271-1286
- DOI
  10.1002/hep.31808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08322
[Journal Article] Envelope Proteins of Hepatitis B Virus: Molecular Biology and Involvement in Carcinogenesis2021
- Author(s)
  Inoue Jun、Sato Kosuke、Ninomiya Masashi、Masamune Atsushi
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 6 Pages: 1124-1124
- DOI
  10.3390/v13061124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08385
[Journal Article] Small Interfering RNA Screening for the Small GTPase Rab Proteins Identifies Rab5B as a Major Regulator of Hepatitis B Virus Production2019
- Author(s)
  Inoue Jun、Ninomiya Masashi、Umetsu Teruyuki、Nakamura Takuya、Kogure Takayuki、Kakazu Eiji、Iwata Tomoaki、Takai Satoshi、Sano Akitoshi、Fukuda Mitsunori、Watashi Koichi、Isogawa Masanori、Tanaka Yasuhito、Shimosegawa Tooru、McNiven Mark A.、Masamune Atsushi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 15
- DOI
  10.1128/jvi.00621-19
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08385, KAKENHI-PROJECT-17K09436, KAKENHI-PROJECT-17H04085
[Journal Article] Cellular membrane trafficking machineries utilized by the hepatitis viruses2018
- Author(s)
  Inoue Jun、Ninomiya Masashi、Shimosegawa Tooru、McNiven Mark A.
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Issue: 2 Pages: 751-762
- DOI
  10.1002/hep.29785
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981
[Journal Article] Reactivation of resolved hepatitis B virus infection with immune escape mutations after long-term corticosteroid therapy2016
- Author(s)
  Inoue J, Kondo Y, Wakui Y, Kogure T, Morosawa T, Fujisaka Y, Umetsu T, Takai S, Nakamura T, Shimosegawa T
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 9 Issue: 2 Pages: 93-98
- DOI
  10.1007/s12328-016-0631-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08981, KAKENHI-PROJECT-16K09335
[Journal Article] Shifting hepatitis B virus genotypes of acute hepatitis B patients in northeast Japan2016
- Author(s)
  Inoue J, Kondo Y, Umetsu T, Yamamoto T, Miura M, Mano Y, Kobayashi T, Obara N, Niitsuma H, Kogure T, Nakagome Y, Kimura O, Iwata T, Morosawa T, Fujisaka Y, Shimosegawa T
- Journal Title
  
  J Med Virol
  
  Volume: 88 Issue: 1 Pages: 69-78
- DOI
  10.1002/jmv.24309
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981, KAKENHI-PROJECT-25460970
[Journal Article] Four-year study of lamivudine and adefovir combination therapy in lamivudine-resistant hepatitis B patients : Influence of hepatitis B virus genotype and resistance mutation pattern2011
- Author(s)
  Inoue J, Ueno Y, Wakui Y, Niitsuma H, Fukushima K, Yamagiwa Y, Shiina M, Kondo Y, Kakazu E, Tamai K, Obara N, Iwasaki T, Shimosegawa T.
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 18 Pages: 206-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] Enhanced replication of hepatitis B virus with frameshift in the precoreregion found in fulminant hepatitis patients2011
- Author(s)
  Inoue J, Ueno Y, Wakui Y, Fukushima K, Kondo Y, Kakazu E, Ninomiya M, Niitsuma H, Shimosegawa T
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 204 Pages: 1017-1025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] B型劇症肝炎におけるgenotype, precore領域frameshiftの意義2011
- Author(s)
  井上淳, 上野義之, 下瀬川徹
- Journal Title
  
  消化器内科
  
  Volume: 53 Pages: 595-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] Enhanced replication of hepatitis B virus with frameshift in the precore region found in fulminant hepatitis patients2011
- Author(s)
  Inoue J, Ueno Y, Wakui Y, Fukushima K, Kondo Y, Kakazu E, Ninomiya M, Niitsuma H, Shimosegawa T
- Journal Title
  
  Infect Dis.
  
  Volume: 204 Pages: 1017-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] Management of chronic hepatitis B patients : Efficacy & limitation of nucleos(t)ide analogues2011
- Author(s)
  Inoue J, Ueno Y, Shimosegawa T
- Journal Title
  
  Indian Journal of Medical Research
  
  Volume: 133 Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] Inhibitory effect on hepatitis B virus in vitro by a peroxisome proliferator-activated receptor-γ ligand, rosiglitazone2010
- Author(s)
  Wakui Y, Inoue J, Ueno Y, Fukushima K, Kondo Y, Kakazu E, Obara N, Kimura O, Shimosegawa T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 396 Pages: 508-514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790627
[Journal Article] Factors involved in the development of fulminant hepatitis B : Are the mutations of hepatitis B virus implicated?2009
- Author(s)
  Jun Inoue
- Journal Title
  
  Hepatology Research 39
  
  Pages: 1053-1055
- Data Source
  KAKENHI-PROJECT-20790483
[Journal Article] Factors involved in the development of fulminant hepatitis B: Are the mutations of hepatitis B virus implicated?2009
- Author(s)
  Inoue J.
- Journal Title
  
  Hepatol Res. 39
  
  Pages: 1053-5
- Data Source
  KAKENHI-PROJECT-20790483
[Journal Article] Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.2009
- Author(s)
  Inoue J, Ueno Y, Nagasaki F, Wakui Y, Kondo Y, Fukushima K, Niitsuma H, Shimosegawa T.
- Journal Title
  
  Virology. 395
  
  Pages: 202-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790483
[Journal Article] Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis2009
- Author(s)
  Jun Inoue, et al.
- Journal Title
  
  Virology 395
  
  Pages: 202-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] IFN-induced MxB on mitochondria inhibits HBV replication by activating a RIG-I-signaling pathway2023
- Author(s)
  Jun Inoue, Masazumi Onuki, Atsushi Masamune
- Organizer
  第31回日本消化器関連学会週間（JDDW 2023）
- Data Source
  KAKENHI-PROJECT-23K07390
[Presentation] 代謝異常関連脂肪性肝疾患 (MAFLD) におけるペマフィブラートおよび各種代謝関連薬の効果の検討2022
- Author(s)
  佐野晃俊、井上　淳、嘉数英二、二宮匡史、岩田朋晃、鶴岡未央、佐藤公亮、小貫真純、澤橋里子、正宗　淳
- Organizer
  第8回肝臓と糖尿病・代謝研究会
- Data Source
  KAKENHI-PROJECT-20K08322
[Presentation] B型肝炎ウイルス感染による小胞輸送の変化がウイルス放出に与える影響2021
- Author(s)
  井上　淳，二宮匡史，正宗　淳
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] Exosome-associated tetraspanin CD63 is a potential target for the inhibition of infectious envelope formation of hepatitis B virus2021
- Author(s)
  Jun Inoue, Masashi Ninomiya, Atsushi Masamune
- Organizer
  第25回日本肝臓学会大会（JDDW2021）
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] Hepatitis B virus infection affects expression of a small GTPase Rab5B resulting in the alteration of viral release2020
- Author(s)
  Jun Inoue, Masashi Ninomiya, Kosuke Sato, Eiji Kakazu, Tomoaki Iwata, Akitoshi Sano, Mio Tsuruoka, Atsushi Masamune
- Organizer
  AASLD The Liver Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] B型肝炎ウイルス粒子形成におけるCD63の役割に関する検討2020
- Author(s)
  井上　淳、二宮匡史、正宗　淳
- Organizer
  第43回　日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] Steatotic hepatocytes release mature very-low-density lipoprotein via methionine and tyrosine metabolism in a Keap1-Nrf2 dependent manner.2020
- Author(s)
  Akitoshi Sano, Eiji Kakazu, Jun Inoue, Masashi Ninomiya, Tomoaki Iwata, Mio Tsuruoka, Kosuke Sato, Atsushi Masamune.
- Organizer
  米国肝臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08322
[Presentation] B型肝炎ウイルスに対するミリストイル化阻害の治療応用の可能性2019
- Author(s)
  井上　淳、二宮　匡史、正宗　淳
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] Rab5BによるHBV粒子放出制御メカニズムの解明と治療応用に向けた検討2019
- Author(s)
  井上　淳、二宮匡史、正宗　淳
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K08385
[Presentation] Rab5B determines HBV release pathways by promoting transport of LHBs from ER to MVB2017
- Author(s)
  Jun Inoue, Teruyuki Umetsu, Takuya Nakamura, Masashi Ninomiya, Takayuki Kogure, Eiji Kakazu, Tomoaki Iwata, Tatsuki Morosawa, Satoshi Takai, Akitoshi Sano, Yasuhito Tanaka, Tooru Shimosegawa
- Organizer
  The 68th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] B型肝炎ウイルスの感染性粒子形成に利用される細胞内小胞輸送経路の解析2017
- Author(s)
  井上　淳，二宮匡史，梅津輝行，中村琢也，小暮高之，嘉数英二，諸沢　樹，高井　智，下瀬川　徹，田中靖人
- Organizer
  第53回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] Enhanced release and infectivity of hepatitis B virus by the depletion of Rab5B2016
- Author(s)
  Jun Inoue, Teruyuki Umetsu, Takuya Nakamura, Masashi Ninomiya, Takayuki Kogure, Tatsuki Morosawa, Satoshi Takai, Yasuhito Tanaka, Tooru Shimosegawa
- Organizer
  2016 HBV International Meeting
- Place of Presentation
  ソウル、韓国
- Year and Date
  2016-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] Alteration of hepatitis B virus particle release after the manipulation of endocytosis-related proteins2016
- Author(s)
  Jun Inoue, Teruyuki Umetsu, Takuya Nakamura, Masashi Ninomiya, Takayuki Kogure, Eiji Kakazu, Tatsuki Morosawa, Satoshi Takai, Yasuhito Tanaka, Tooru Shimosegawa
- Organizer
  The 67th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  ボストン、アメリカ
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] B型肝炎ウイルスの感染性粒子形成に必要な小胞輸送機構の解析2016
- Author(s)
  井上　淳、梅津輝行、中村琢也、二宮匡史、小暮高之、嘉数英二、諸沢　樹、高井　智、下瀬川　徹
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張、千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] Comprehensive analysis of the Rab family to screen membrane traffic pathways utilized by hepatitis B virus2015
- Author(s)
  Jun Inoue, Yasuteru Kondo, Teruyuki Umetsu, Takuya Nakamura, Takayuki Kogure, Yu Nakagome, Yuta Wakui, Tatsuki Morosawa, Yasuyuki Fujisaka, Satoshi Takai, Tooru Shimosegawa
- Organizer
  The 66th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2015-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] B型肝炎ウイルスの生活環後期で作用するRabタンパク質の網羅的解析2015
- Author(s)
  井上　淳、近藤泰輝、下瀬川　徹
- Organizer
  第51回　日本肝臓学会総会
- Place of Presentation
  熊本ホテルキャッスル、熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K08981
[Presentation] Yasuteru Kondo, Eiji Kakazu, Masashi Ninomiya, Osamu Kimura, Tooru Shimosegawa. Association between Mutations in a Cytotoxic T Lymphocyte Epitope of Hepatitis B Virus and Fulminant Hepatitis2011
- Author(s)
  Jun Inoue, Yoshiyuki Ueno, Hirofumi Niitsuma
- Organizer
  The 62th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  サンフランシスコ, 米国
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] Association between Mutations in a Cytotoxic T Lymphocyte Epitope of Hepatitis B Virus and Fulminant Hepatitis2011
- Author(s)
  Jun Inoue, Yoshiyuki Ueno, Hirofumi Niitsuma, Yasuteru Kondo, Eiji Kakazu, Masashi Ninomiya, Osamu Kimura, Tooru Shimosegawa
- Organizer
  The 62th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  サンフランシスコ、米国
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] Genotype B1/BjのHBVによる劇症肝炎とCTL epitope変異の関連2011
- Author(s)
  井上淳, 上野義之, 涌井祐太, 福島耕治, 近藤泰輝, 嘉数英二, 二宮匡史, 新妻宏文, 三浦雅人, 下瀬川徹
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] The Significance of Frameshift in the Precore Region of Hepatitis B Virus Obtained from Fulminant Hepatitis Patients2010
- Author(s)
  Jun Inoue, Yoshiyuki Ueno, Yuta Wakui, Koji Fukushima, Yasuteru Kondo, Eiji Kakazu, Masashi Ninomiya, Hirofumi Niitsuma, Tooru Shimosegawa
- Organizer
  The 61th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  ボストン, 米国
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] B型劇症肝炎におけるgenotype, precore領域frameshiftの意義2010
- Author(s)
  井上淳, 上野義之, 下瀬川徹
- Organizer
  第14回日本肝臓学会大会(JDDW2010)
- Place of Presentation
  横浜
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] The Significance of Frameshift in the Precore Region of Hepatitis B Virus Obtained from Fulminant Hepatitis Patients2010
- Author(s)
  Jun Inoue, Yoshiyuki Ueno, Yuta Wakui, Koji Fukushima, Yasuteru Kondo, Eiji Kakazu, Masashi Ninomiya, Hirofumi Niitsuma, Tooru Shimosegawa
- Organizer
  The 61th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  ボストン、米国
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] B型劇症肝炎におけるgenotype,precore領域frameshiftの意義2010
- Author(s)
  井上淳, 上野義之, 下瀬川徹
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22790627
[Presentation] Emergence of multiple drug-resistant mutants of hepatitis B virus with long-term lamivudine and adefovir bitherapy2009
- Author(s)
  井上淳, et al.
- Organizer
  The 60th Annual Meeting of the American Association for the Study of Liver Disease(AASLD)
- Place of Presentation
  Boston(米国)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Adefovir耐性B型肝炎例に認められた新たな変異とその対策について.2009
- Author(s)
  井上淳, 他
- Organizer
  第13回日本肝臓学会大会(JDDW 2009)
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Emergence of multiple drug-resistant mutants of hepatitis B virus with long-term lamivudine and adefovir bitherapy.2009
- Author(s)
  Inoue J, et al
- Organizer
  The 60th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  Boston. USA
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Adefovir 耐性B型肝炎例に認められた新た無変異とその対策について2009
- Author(s)
  井上淳, 他
- Organizer
  第13回日本肝臓学会大会(JDDW2009)
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] 劇症肝炎患者から得られたHBV株の持つ細胞障害性についての検討2008
- Author(s)
  井上淳, 他
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Cytopathic effect of hepatitis B virus obtained from fulminant hepatitis patients2008
- Author(s)
  井上淳
- Organizer
  The 59th Annual Meeting of the American Association for the Study of Liver Disease
- Place of Presentation
  サンフランシスコ(アメリカ)
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Cytopathic effect of hepatitis B virus obtained from fulminant hepatitis patients.2008
- Author(s)
  Inoue J, et al.
- Organizer
  The 59th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  San Francisco. USA
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-20790483
[Presentation] Hepatitis B virus enhances the endo-lysosomal pathway through the activation of the small GTPase Rab7 via an interaction between HBe and the Rab7 GAP, TBC1D15
- Author(s)
  Jun Inoue, Eugene W. Krueger, Jing Chen, Hong Cao, Tooru Shimosegawa, Mark A. McNiven
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-26893011
[Presentation] 仙台市におけるB型急性肝炎のgenotypeの推移およびgenotype毎の特徴の解析
- Author(s)
  井上　淳、近藤　泰輝、下瀬川　徹
- Organizer
  第40回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2014-11-27 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-26893011
[Presentation] B型肝炎ウイルスによる小胞輸送システムの変化と治療応用の可能性
- Author(s)
  井上　淳、近藤　泰輝、下瀬川　徹
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台
- Year and Date
  2015-04-23 – 2015-04-25
- Data Source
  KAKENHI-PROJECT-26893011

1. 二宮匡史 (70583938)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. Kakazu Eiji (20509377)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 岩田朋晃 (30803647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 濱田晋 (20451560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 小暮高之 (70400330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 菅原明 (90270834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岩渕好治 (20211766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 横山敦 (20572332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岡本好司 (80572247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐野晃俊 (20906060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 山添太士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inoue Jun 井上 淳

INOUE Jun 井上 淳

JUN Inoue 井上 淳

Research Projects

Research Products

Co-Researchers

新規ChREBP阻害薬の標的遺伝子に対するPerturbシークエンスを用いたNAFLDの病態制御

Principal Investigator

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ミトコンドリアを介する自然免疫応答を標的としたB型肝炎ウイルスの制御と肝発癌抑制Principal Investigator

Principal Investigator

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Impact of free amino acids on intracellular stress response mechanisms in hepatic steatosis.

Principal Investigator

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Research Institution

Mechanistic analysis of hepatitis B virus infection focusing on vesicle trafficking system and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysis of vesicle trafficking pathways utilized for the life cycle of hepatitis B virus and its application for therapiesPrincipal Investigator

Principal Investigator

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B型肝炎ウイルスの生活環に必要な小胞輸送の分子スイッチの解明Principal Investigator

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Comprehensive study of hepatitis B virus genotypes and mutations involved in the pathogenesisPrincipal Investigator

Principal Investigator

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Analysis of the mechanism of fulminant hepatitis using a hepatitisB virus strain obtained from a patient in fulminant hepatitis outbreakPrincipal Investigator

Principal Investigator

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Research Institution

[Book] 肝胆膵 Vol.71 No.6 Dec. 特集 肝炎ウイルス A to E2015

Author(s)

Total Pages

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Data Source

[Journal Article] Usefulness of the Fibrosis‐4 index and alanine aminotransferase at 1 year of nucleos(t)ide analog treatment for prediction of hepatocellular carcinoma in chronic hepatitis B patients2024

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[Journal Article] Effects of sodium glucose cotransporter 2 inhibitors and pioglitazone on FIB‐4 index in metabolic‐associated fatty liver disease2023

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[Journal Article] The Exosome‐Associated Tetraspanin CD63 Contributes to the Efficient Assembly and Infectivity of the Hepatitis B Virus2021

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[Journal Article] Steatotic hepatocytes release mature VLDL via methionine and tyrosine metabolism in a Keap1‐Nrf2 dependent manner2021

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[Journal Article] Envelope Proteins of Hepatitis B Virus: Molecular Biology and Involvement in Carcinogenesis2021

Inoue Jun 井上淳

INOUE Jun 井上淳

JUN Inoue 井上淳

[Book] 肝胆膵 Vol.71 No.6 Dec.　特集　肝炎ウイルス A to E2015