ICHIKAWA DAIJU 市川大樹

… Alternative Names

市川大樹イチカワダイジュ

ICHIKAWA Daiju 市川大樹

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Researcher Number	60462793
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 慶應義塾大学, 薬学部(芝共立), 助教 2016 – 2017: 慶應義塾大学, 薬学部(芝共立), 助教 2010: 独)国立精神・神経医療研究センター, 神経研究所免疫研究部, 研究員 2009: National Center of Neurology and Psychiatry, 神経研究所免疫研究部, 流動研究員 2009: National Center of Neurology and Psychiatry, 神経研究所免疫研究部, 流動研究員 2008: National Center of Neurology and Psychiatry, 神経研究所・免疫研究部, 流動研究員 2008: 国立精神・神経センター, 神経研究所免疫研究部, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Pathological medical chemistry / Biological pharmacy Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 多発性骨髄腫 / 薬剤耐性 / 免疫調節薬 / IMiDs / エピゲノム / レナリドミド / 耐性 / LncRNA / lncRNA / CRBN非依存性 … More / シグナル伝達 / 癌 / 血液がん / CRBN非依存 / TC11 / IMiDs抵抗性 / E3リガーゼ / 自己免疫 / 細胞骨格 / 免疫寛容 / GRAIL / T細胞アナジー / 免疫学 … More Except Principal Investigator 腸内細菌叢 / 免疫調節性細胞 / 関節炎 / MR1 / NKT細胞 Less

エピゲノム制御による薬剤抵抗性難治性造血器腫瘍の克服Principal Investigator
- Principal Investigator
  
  市川大樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
Overcoming resistance to new drug in hematological malignancy tageting LncRNA.Principal Investigator
- Principal Investigator
  
  ICHIKAWA DAIJU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
Identification of novel therapeutic target molecules and the molecular mechanism for refractory multiple myelomaPrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Daiju
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University
The role of MRI restricted T cells in arthritis
- Principal Investigator
  
  MIYAKE Sachiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  National Center of Neurology and Psychiatry
The role of GRAIL in immune tolerancePrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Daiju
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Center of Neurology and Psychiatry

All 2023 2017 2010 2009 2008

All Journal Article Presentation

[Journal Article] Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma.2017
- Author(s)
  Suto Y, Sato M, Fujimori K, Kitabatake S, Okayama M, Ichikawa D, Matsushita M, Yamagiwa N, Iwasaki G, Kiuchi F, Hattori Y.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 19 Pages: 4558-4563
- DOI
  10.1016/j.bmcl.2017.08.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09940, KAKENHI-PROJECT-16K19059
[Journal Article] NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome.2017
- Author(s)
  Hayakawa K, Formica AM, Zhou Y, Ichikawa D, Asano M, Li YS, Shinton SA, Brill-Dashoff J, Nunez G, Hardy RR.
- Journal Title
  
  J Exp Med.
  
  Volume: 214 Issue: 10 Pages: 3067-3083
- DOI
  10.1084/jem.20170497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19059
[Journal Article] A novel phenylphthalimide derivative, pegylated TC11, improves pharmacokinetic properties and induces apoptosis of high-risk myeloma cells via G2/M cell-cycle arrest.2017
- Author(s)
  Aida S, Hozumi M, Ichikawa D, Iida K, Yonemura Y, Tabata N, Yamada T, Matsushita M, Sugai T, Yanagawa H, Hattori Y
- Journal Title
  
  Biochem. Biophysic. Res. Commun.
  
  Volume: 493 Issue: 1 Pages: 514-520
- DOI
  10.1016/j.bbrc.2017.08.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09940, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16K19059
[Presentation] エピジェネティック因子CDYL2は多発性骨髄腫におけるレナリドミド感受性を減弱する2023
- Author(s)
  市川大樹, 上岡優菜, 松下麻衣子, 服部豊
- Organizer
  第48回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07258
[Presentation] エピゲネティック因子CDYL2は多発性骨髄腫におけるレナリドミド耐性に関連する2023
- Author(s)
  市川大樹、松下麻衣子、服部豊
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K07258
[Presentation] Cereblon-independent anti-myeloma pathway of TC11, a novel compound of immunomodulatory drugs2017
- Author(s)
  Misa Nakamura, Daiju Ichikawa, Shuji Aida, Nahoko Hashimoto, Wakana Murota, Ryo Uozaki, Mikio Okayama, Kota Fujimori,Yuko Yonemura, Noriko Tabata, Hiroshi Yanagawa, Maiko Matsushita, Yutaka Hattori
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K19059
[Presentation] PEG(E)-TC11, a novel polyethylene glycol-linked phthalimide derivative, inhibited high-risk MM cell growth in vivo and in vitro via cell cycle G2/M arrest in a CRBN-independent manner.2017
- Author(s)
  Shuji Aida, Daiju Ichikawa, Kazuki Iida, Masashi Hozumi, Misa Nakamura, Ryo Uozaki, Nahoko Hashimoto, Mikio Okayama, Yuko Yonemura, Noriko Tabata, Taketo Yamada, Maiko Matsushita, Takeshi Sugai, Hiroshi Yanagawa, Yutaka Hattori
- Organizer
  American association for cancer research annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19059
[Presentation] PEG(E)-TC11はCRBN非依存的に細胞周期の調節を介してハイリスク骨髄腫の増殖を抑制する2017
- Author(s)
  會田宗司, 市川大樹, 中村美沙, 宇於崎涼, 飯田和樹, 穂積暢史, 岡山幹夫, 藤森宏太, 米村裕子, 田畠典子, 山田健人, 松下麻衣子, 須貝威, 柳川弘志, 服部豊
- Organizer
  第42回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19059
[Presentation] Mucosal associated invariant T cells contribute to the pathogenesis of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  American College of Rheumatology 73^<th> Annual Scientific Meeting
- Place of Presentation
  Georgia World Congress Center, Atlanta, Georgia
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of murines models of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  10^<th> Annual Conference of FOCIS(Clinical Immunology, 135S:S52, 2010)
- Place of Presentation
  Boston
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] Celecoxib analogue lacking COX-2 inhibitory activity suppresses inflammatory disorders by inhibiting inflammatory cytokines.2010
- Author(s)
  Chiba A, Miyazaki Y, Ryohsuke T, Miho M, Tomi C, Ichikawa D, Iraide A, Yamamura T, Vandenbroeck K, Miyake S
- Organizer
  10^<th> International Congress of Neuroimmunology
- Place of Presentation
  Hotel Melia Sitges, Barcelona
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Portopia Hotel, Kobe
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] Celecoxib analogue lacking COX-2 inhibitory activity inhibits arthritis by suppressing IL-23 and inflammatory cytokines2010
- Author(s)
  Chiba A, Ryohsuke T, Miho M, Tomi C, Ichikawa D, Iraide A, Yamamura T, Vandenbroeck K, Miyake S
- Organizer
  American College of Rheumatology 73^<th> Annual Scientific Meeting (Arthritis Rheum. 62:S371,2010)
- Place of Presentation
  Atlanta, Georgia
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] Celecoxib analogue lacking COX-2 inhibitory activity inhibits arthritis by suppressing IL-23 and inflammatory cytokines2010
- Author(s)
  Chiba A, Ryohsuke T, Miho M, Tomi C, Ichikawa D, Iraide A, Yamamura T, Vandenbroeck K, Miyake S
- Organizer
  American College of Rheumatology 73^<th> Annual Scientific Meeting
- Place of Presentation
  Georgia World Congress Center, Atlanta, Georgia
- Year and Date
  2010-11-07
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of murines models of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  10^<th> Annual Conference of FOCIS
- Place of Presentation
  FOCIS2010会場(マリオットホテル)、Boston
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] Celecoxib analogue lacking COX-2 inhibitory activity suppresses inflammatory disorders by inhibiting inflammatory cytokines2010
- Author(s)
  Chiba A, Miyazaki Y, Ryohsuke T, Miho M, Tomi C, Ichikawa D, Iraide A, Yamamura T, Vandenbroeck K, Miyake S
- Organizer
  10^<th> International Congress of Neuroimmunology
- Place of Presentation
  Barcelona
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] Mucosal associated invariant T cells contribute to the pathogenesis of arthritis2010
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  American College of Rheumatology 73^<th> Annual Scientific Meeting(Arthritis Rheum. 62:S938, 2010)
- Place of Presentation
  Atlanta, Georgia
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] 新規 celecoxib アナログはTh17, Th1細胞の抑制を介して多発性硬化症, 関節リウマチのマウスモデルを抑制する2009
- Author(s)
  宮崎雄生, 千葉麻子, 水野美歩, 任海千春, 市川大樹, Iraide Alloza, 山村隆, Koen Vanden broeck, 三宅幸子
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-lrestricted MAIT cells in the pathogenesis of arthritis2009
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, Ichikawa D, Yamamura T, Miyake S
- Organizer
  American College of Rheumatology 73rd Annual Scientific Meeting
- Place of Presentation
  Philadelphia, Pennsylvania Convention Center
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] 新規celecoxibアナログはTh17,Th1細胞の抑制を介して多発性硬化症,関節リウマチのマウスモデルを抑制する2009
- Author(s)
  宮崎雄生,千葉麻子,水野美歩,任海千春,市川大樹,Iraide Alloza,山村隆,Koen Vandenbroeck,三宅幸子
- Organizer
  ワークショップ18,第39回日本免疫学会総会
- Place of Presentation
  大坂
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of arthritis2009
- Author(s)
  Chiba A, Tajima R, Miyazaki Y, 市川大樹, Yamamura T, Miyake S
- Organizer
  American College of Rheumatology 73rd Annual Scientific Meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] 炎症性関節炎におけるMR1拘束性MSIT細胞の役割2009
- Author(s)
  千葉麻子、宮崎雄生、市川大樹、山村隆、三宅幸子
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] T細胞アナジーに関連したE3リガーゼGRAILの基質同定2009
- Author(s)
  市川大樹, 水野美歩, 大木伸司, 山村隆, 三宅幸子
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪国際会議場, 大阪
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20790093
[Presentation] T細胞アナジーに関連したE3リガーゼGRAILの基質同定2009
- Author(s)
  市川大樹
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪,大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20790093
[Presentation] T細胞アナジーに関連したE3リガーゼGRAILの基質同定2009
- Author(s)
  市川大樹,水野美歩,大木伸司,山村隆,三宅幸子
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] 炎症性関節炎におけるMR1拘束性MAIT細胞の役割2009
- Author(s)
  千葉麻子、宮崎雄生、市川大樹、山村隆、三宅幸子
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] MR1拘束性Va19iT細胞の抗体誘導関節炎における機能解析2008
- Author(s)
  田島良亮、山村隆、宮崎雄生、市川大樹、三宅幸子
- Organizer
  第38回日本免疫学会(第38回日本免疫学会総会抄録集p91)
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20390284
[Presentation] 腸管免疫制御におけるmucosao associated invariant T細胞の役割2008
- Author(s)
  宮崎雄生、田島良亮、市川大樹、八子徹、三宅幸子、山村隆
- Organizer
  第38回日本免疫学会(第38回日本免疫学会総会抄録集p98)
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20390284

1. MIYAKE Sachiko (50266045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. 服部豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 木内文之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山田健人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ICHIKAWA DAIJU 市川 大樹

市川 大樹 イチカワ ダイジュ

ICHIKAWA Daiju 市川 大樹

Research Projects

Research Products

Co-Researchers

エピゲノム制御による薬剤抵抗性難治性造血器腫瘍の克服Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Overcoming resistance to new drug in hematological malignancy tageting LncRNA.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel therapeutic target molecules and the molecular mechanism for refractory multiple myelomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of MRI restricted T cells in arthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of GRAIL in immune tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel phenylphthalimide derivative, pegylated TC11, improves pharmacokinetic properties and induces apoptosis of high-risk myeloma cells via G2/M cell-cycle arrest.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] エピジェネティック因子CDYL2は多発性骨髄腫におけるレナリドミド感受性を減弱する2023

Author(s)

Organizer

Data Source

[Presentation] エピゲネティック因子CDYL2は多発性骨髄腫におけるレナリドミド耐性に関連する2023

Author(s)

Organizer

Data Source

[Presentation] Cereblon-independent anti-myeloma pathway of TC11, a novel compound of immunomodulatory drugs2017

Author(s)

Organizer

Data Source

[Presentation] PEG(E)-TC11, a novel polyethylene glycol-linked phthalimide derivative, inhibited high-risk MM cell growth in vivo and in vitro via cell cycle G2/M arrest in a CRBN-independent manner.2017

Author(s)

Organizer

Data Source

[Presentation] PEG(E)-TC11はCRBN非依存的に細胞周期の調節を介してハイリスク骨髄腫の増殖を抑制する2017

Author(s)

Organizer

Data Source

[Presentation] Mucosal associated invariant T cells contribute to the pathogenesis of arthritis2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The role of MR-1restricted MAIT cells in the pathogenesis of murines models of arthritis2010

Author(s)

Organizer

ICHIKAWA DAIJU 市川大樹

市川大樹イチカワダイジュ

ICHIKAWA Daiju 市川大樹