Nagamatsu Takeshi 永松健

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NAGAMATSU Takeshi 永松健

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Researcher Number	60463858
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, 国際医療福祉大学成田病院, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 国際医療福祉大学, 国際医療福祉大学成田病院, 教授 2016 – 2021: 東京大学, 医学部附属病院, 准教授 2017: 東京大学, 医学部附属病院, その他 2017: 東京大学, 医学部附属病院・産科女性診療科, 准教授 2013 – 2015: 東京大学, 医学部附属病院, 講師 2010 – 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56040:Obstetrics and gynecology-related / Hygiene and public health / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 早産 / 妊娠 / プロテアーゼ / 子宮頸管熟化 / 抗菌ペプチド / DOHaD / 胎内環境 / 血管新生因子 / 妊娠高血圧症候群 / 治療 … More / トロンボモジュリン / HMGB1 / 妊娠高血圧腎症 / 抗プロテアーゼ / プログラニュリン / SLPI / 炎症制御 / 抗炎症蛋白 / 頸管熟化 / 炎症 / 羊膜絨毛膜炎 / 産婦人科学 / 共刺激分子 / 免疫 / 脱落膜 / マクロファージ … More Except Principal Investigator 妊娠 / 妊娠高血圧症候群 / 胎盤 / 脂質 / 絨毛細胞 / トロンボモデュリン / トロンボモジュリン / ドラッグデリバリーシステム / オートタキシン / レニンーアンギオテンシン / 妊娠高血圧腎症 / 酸化ストレス / スタチン / リゾフォスファチジン酸 / マウスモデル / 医療・福祉 / 栄養学 / トランスレーショナルリサーチ / レゾルビン / SLPI / RvE3 / 18-HEPE / EPA / 炎症 / 早産 / オメガ3脂肪酸 / ナノデバイス / ナノバイオ / Anticancer drugs / Cancer / マクロファージ標的 / 抗炎症治療 / 抗癌治療 / 胎盤輸送 / 高分子ナノメディシン / Star-shaped polymers / Polymeric micelles / Preeclampsia / Preterm birth / Size effect / Placental barrier / Pre-eclampsia / Pre-term birth / Size control / Nanomedicine / Placenta / 胎盤形成 / 周産期 / リゾリン脂質 / 微小環境 / 着床 / プロゲステロン / 子宮内膜 / リゾホスファチジン酸 / 脂質メディエーター / 光拡散分光 / 虚血性低酸素性脳障害 / 拡散反射分光法 / 新生児 / 低酸素性虚血性脳障害 / 分娩 / ラットモデル / 拡散反射分光 / 低酸素虚血性脳障害 Less

胚低栄養環境による成人病発症の機序解明と妊娠母体への栄養介入による発症抑制法開発Principal Investigator
- Principal Investigator
  
  永松健
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  International University of Health and Welfare
The pathogenesis of preeclampsia focusing on the vascular endothelial dysfunction by HMGB1 and the search for new therapeutic agents.Principal Investigator
- Principal Investigator
  
  Nagamatsu Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  International University of Health and Welfare
  The University of Tokyo
Development of drug delivery system using nano-micelle carrier targeting placenta complicated with preeclampsia
- Principal Investigator
  
  Fujii Tomoyuki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Development of novel approach for prevention of preterm birth by inhibiting cervical ripening using anti-inflammatory proteinsPrincipal Investigator
- Principal Investigator
  
  Nagamatsu Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Application of nanomedicine therapy for hypertensive disorders of pregnancy focusing on the molecular mechanisms related to oxidative stress regulation the placenta
- Principal Investigator
  
  Fujii Tomoyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Development of a nano-pharmaceutical strategy for safely and effectively treating pregnant cancer patients
- Principal Investigator
  
  Cabral Horacio
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
The study about omega-3 fatty acids and their metabolites as preventive drugs for premature birth
- Principal Investigator
  
  Yamashita Aki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  The University of Tokyo
Study on molecular mechanism of cervical maturation focusing on anti-protease systemPrincipal Investigator
- Principal Investigator
  
  Nagamatsu Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Development of novel real time monitaring for fetal brain metabolism using diffuse reflectance
- Principal Investigator
  
  Fujii Tomoyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Regulatory mechanism of microenvironment at fetomaternal interface by lipid mediators and progesterone
- Principal Investigator
  
  Fujii Tomoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Immulogogical system mediated by antimicropeptide at the uterine cervixPrincipal Investigator
- Principal Investigator
  
  NAGAMATSU Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
Basic Study of functionality and cell differentiation of decidual macrophages targeting the development of novel clinical approach for the prediction and the therapy of preterm delivery.Principal Investigator
- Principal Investigator
  
  NAGAMATSU Takeshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

[Journal Article] Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia2024
- Author(s)
  Oda Hiroko、Nagamatsu Takeshi、Iriyama Takayuki、Osuga Yutaka
- Journal Title
  
  Placenta
  
  Volume: 148 Pages: 12-19
- DOI
  10.1016/j.placenta.2024.01.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09442
[Journal Article] Clinical characteristics and outcomes of women with adenomyosis pain during pregnancy: a retrospective study2023
- Author(s)
  Sayama Seisuke、Iriyama Takayuki、Takeiri Yotaro、Hashimoto Ayako、Toshimitsu Masatake、Ichinose Mari、Seyama Takahiro、Sone Kenbun、Kumasawa Keiichi、Nagamatsu Takeshi、Koga Kaori、Osuga Yutaka
- Journal Title
  
  Journal of Perinatal Medicine
  
  Volume: 52 Issue: 2 Pages: 186-191
- DOI
  10.1515/jpm-2023-0263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09442
[Journal Article] Upregulation of autotaxin by oxidative stress via Nrf2 activation: A novel insight into the compensation mechanism in preeclamptic placenta2023
- Author(s)
  Yanagisawa Manami、Nagamatsu Takeshi、Kurano Makoto、Misumi Fumi、Taguchi Ayumi、Akiba Naoya、Ichinose Mari、Kumasawa Keiichi、Iriyama Takayuki、Fujii Tomoyuki、Yatomi Yutaka、Osuga Yutaka
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 160 Pages: 104153-104153
- DOI
  10.1016/j.jri.2023.104153
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15828, KAKENHI-PROJECT-21K09442, KAKENHI-PROJECT-22K20935
[Journal Article] Pregnancy‐induced hemorrhagic degeneration of adenomyosis2022
- Author(s)
  Nakanishi Megumi、Iriyama Takayuki、Sayama Seisuke、Hanaoka Shouhei、Toshimitsu Masatake、Seyama Takahiro、Sone Kenbun、Kumasawa Keiichi、Nagamatsu Takeshi、Osuga Yutaka
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 48 Issue: 5 Pages: 1265-1270
- DOI
  10.1111/jog.15195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09442, KAKENHI-PROJECT-20K18158
[Journal Article] Thrombomodulin and pregnancy in the limelight: Insights into the therapeutic aspect of thrombomodulin in pregnancy complications2022
- Author(s)
  Oda Hiroko、Nagamatsu Takeshi、Osuga Yutaka
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: 20 Issue: 5 Pages: 1040-1055
- DOI
  10.1111/jth.15680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09442
[Journal Article] Suppression of human trophoblast syncytialization by human cytomegalovirus infection2022
- Author(s)
  Mimura Nobuko、Nagamatsu Takeshi、Morita Kazuki、Taguchi Ayumi、Toya Takashi、Kumasawa Keiichi、Iriyama Takayuki、Kawana Kei、Inoue Naoki、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  Placenta
  
  Volume: 117 Pages: 200-208
- DOI
  10.1016/j.placenta.2021.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578, KAKENHI-PROJECT-21K09442
[Journal Article] Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy2021
- Author(s)
  Samejima Taiki、Nagamatsu Takeshi、Akiba Naoya、Fujii Tatsuya、Sayama Seisuke、Kawana Kei、Taguchi Ayumi、Kumasawa Keiichi、Iriyama Takayuki、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 143 Pages: 103241-103241
- DOI
  10.1016/j.jri.2020.103241
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-20K09613, KAKENHI-PROJECT-20K18158
[Journal Article] Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia-induced FLT1 gene in placental trophoblasts2021
- Author(s)
  Sasagawa Tadashi、Nagamatsu Takeshi、Yanagisawa Manami、Fujii Tomoyuki、Shibuya Masabumi
- Journal Title
  
  Molecular Human Reproduction
  
  Volume: 27 Issue: 12 Pages: 1-1
- DOI
  10.1093/molehr/gaab065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09442, KAKENHI-PROJECT-20K09675
[Journal Article] Recombinant Thrombomodulin Attenuates Preeclamptic Symptoms by Inhibiting High-Mobility Group Box 1 in Mice2021
- Author(s)
  Oda Hiroko、Nagamatsu Takeshi、Schust Danny J、Cabral Horacio、Miyazaki Takuya、Iriyama Takayuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Endocrinology
  
  Volume: 162 Issue: 4
- DOI
  10.1210/endocr/bqaa248
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-19K22678, KAKENHI-PROJECT-19K23614, KAKENHI-PROJECT-21K18070
[Journal Article] Impact of additional risk factors on the incidence of preterm delivery among pregnant women diagnosed with short cervix2020
- Author(s)
  Samejima Taiki、Nagamatsu Takeshi、Iriyama Takayuki、Nakayama Toshio、Seyama Takahiro、Sayama Seisuke、Kumasawa Keiichi、Komatsu Atsushi、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Taiwanese Journal of Obstetrics and Gynecology
  
  Volume: 59 Issue: 2 Pages: 195-199
- DOI
  10.1016/j.tjog.2020.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-18K09303
[Journal Article] 疾患と検査値の推移　妊娠高血圧症候群.2020
- Author(s)
  永松　健
- Journal Title
  
  検査と技術
  
  Volume: 48 Pages: 148-153
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Production of an anti-angiogenic factor sFLT1 is suppressed via promoter hypermethylation of FLT1 gene in choriocarcinoma cells2020
- Author(s)
  Sasagawa Tadashi、Jinno-Oue Atsushi、Nagamatsu Takeshi、Morita Kazuki、Tsuruga Tetsushi、Mori-Uchino Mayuyo、Fujii Tomoyuki、Shibuya Masabumi
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 112-112
- DOI
  10.1186/s12885-020-6598-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22678
[Journal Article] Abdominal compartment syndrome complicated by preeclampsia and partial HELLP syndrome in a 45‐year‐old woman: A case report2020
- Author(s)
  Kumasawa Keiichi、Kubota Kaori、Takahashi Yuko、Nakayama Toshio、Iriyama Takayuki、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Clinical Case Reports
  
  Volume: 8 Issue: 7 Pages: 1251-1254
- DOI
  10.1002/ccr3.2904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22678
[Journal Article] ASK1 promotes uterine inflammation leading to pathological preterm birth2020
- Author(s)
  Yoshikawa Midori、Iriyama Takayuki、Suzuki Kensuke、Sayama Seisuke、Tsuruga Tetsushi、Kumasawa Keiichi、Nagamatsu Takeshi、Homma Kengo、Naguro Isao、Osuga Yutaka、Ichijo Hidenori、Fujii Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1887-1887
- DOI
  10.1038/s41598-020-58653-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22678, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02569, KAKENHI-PROJECT-19H03796, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-18H03995
[Journal Article] Pravastatin for preeclampsia: From animal to human2020
- Author(s)
  Kumasawa Keiichi、Iriyama Takayuki、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 46 Issue: 8 Pages: 1255-1262
- DOI
  10.1111/jog.14295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Ultrasonographic vascularity assessment for predicting future severe hemorrhage in retained products of conception after second-trimester abortion2019
- Author(s)
  Akiba Naoya、Iriyama Takayuki、Nakayama Toshio、Seyama Takahiro、Sayama Seisuke、Kumasawa Keiichi、Komatsu Atsushi、Yabe Shinichiro、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  The Journal of Maternal-Fetal & Neonatal Medicine
  
  Volume: ahead of print Issue: 4 Pages: 1-7
- DOI
  10.1080/14767058.2019.1610739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-20K09613
[Journal Article] 【妊娠高血圧症候群update】病態　胎盤sflt-1の発現.2019
- Author(s)
  永松　健
- Journal Title
  
  周産期医学
  
  Volume: 49 Pages: 1352-1353
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Management of a pregnant woman with hypouricemia: a case report2019
- Author(s)
  Kumasawa Keiichi、Nakayama Toshio、Hashimoto Ayako、Kubota Kaori、Takahashi Yuko、Furuya Hitomi、Shitara Rieko、Seyama Takahiro、Tsuruga Tetsushi、Iriyama Takayuki、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Oxford Medical Case Reports
  
  Volume: 2019 Issue: 5
- DOI
  10.1093/omcr/omz035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia2019
- Author(s)
  Iriyama Takayuki、Wang Guan、Yoshikawa Midori、Mimura Nobuko、Matsui Haruka、Sayama Seisuke、Kumasawa Keiichi、Nagamatsu Takeshi、Koga Kaori、Kotani Tomomi、Niimi Kaoru、Yamamoto Eiko、Kellems Rodney E.、Xia Yang、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 01017-01017
- DOI
  10.1038/s41598-019-46660-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-16H05469
[Journal Article] Successful right heart remodelling and subsequent pregnancy in a patient with chronic thromboembolic pulmonary hypertension undergoing balloon pulmonary angioplasty: a case report2019
- Author(s)
  Ikeda Nobutaka、Hatano Masaru、Nagamatsu Takeshi、Nakamura Masato
- Journal Title
  
  European Heart Journal - Case Reports
  
  Volume: 3 Issue: 2
- DOI
  10.1093/ehjcr/ytz063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia2019
- Author(s)
  Fujii Tatsuya、Nagamatsu Takeshi、Schust Danny J.、Ichikawa Mayuko、Kumasawa Keiichi、Yabe Shinichiro、Iriyama Takayuki、Hirota Yasushi、Osuga Yutaka、Aoki Junken、Yatomi Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 82 Issue: 5
- DOI
  10.1111/aji.13176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22678, KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-18K19601, KAKENHI-PROJECT-16H04679, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-19H03144
[Journal Article] Tokishakuyakusan, a traditional Japanese medicine (Kampo) mitigates iNKT cell-mediated pregnancy loss in mice2018
- Author(s)
  Nagamatsu Takeshi、Fujii Tatsuya、Schust Danny J.、Tsuchiya Naoko、Tokita Yohei、Hoya Mari、Akiba Naoya、Iriyama Takayuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 80 Issue: 4
- DOI
  10.1111/aji.13021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-16H06266
[Journal Article] 【産婦人科感染症の診断・管理-その秘訣とピットフォール】早産と周産期感染症早産の機序と生体反応2018
- Author(s)
  永松健
- Journal Title
  
  . 臨床婦人科産科
  
  Volume: 72 Pages: 125-131
- Data Source
  KAKENHI-PROJECT-15K10661
[Journal Article] Molecular Mechanisms to Regulate Trophoblast Cell Functions and Cervical2018
- Author(s)
  永松　健
- Journal Title
  
  日本産科婦人科学会雑誌ACTA OBST GYNAEC JPN
  
  Volume: 70 Pages: 2604-2614
- Data Source
  KAKENHI-PROJECT-18K09220
[Journal Article] HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts2018
- Author(s)
  Sasagawa Tadashi、Nagamatsu Takeshi、Morita Kazuki、Mimura Nobuko、Iriyama Takayuki、Fujii Tomoyuki、Shibuya Masabumi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 17375-17375
- DOI
  10.1038/s41598-018-35745-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Impact of Th1/Th2 cytokine polarity induced by invariant NKT cells on the incidence of pregnancy loss in mice2018
- Author(s)
  Hoya Mari、Nagamatsu Takeshi、Fujii Tatsuya、Schust Danny J.、Oda Hiroko、Akiba Naoya、Iriyama Takayuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 79 Issue: 3
- DOI
  10.1111/aji.12813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-16H06266
[Journal Article] Molecular Mechanisms to Regulate Trophoblast Cell Functions and Cervical2018
- Author(s)
  永松　健
- Journal Title
  
  日本産科婦人科学会雑誌ACTA OBST GYNAEC JPN
  
  Volume: 70
- Data Source
  KAKENHI-PROJECT-18H02943
[Journal Article] Elevation of maternal serum sFlt-1 in pregnancy with mirror syndrome caused by fetal cardiac failure2018
- Author(s)
  Katoh Yoshihisa、Seyama Takahiro、Mimura Nobuko、Furuya Hitomi、Nakayama Toshio、Iriyama Takayuki、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Oxford Medical Case Reports
  
  Volume: 2018 Issue: 3
- DOI
  10.1093/omcr/omx112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-16H06266
[Journal Article] Labor prediction based on the expression patterns of multiple genes related to cervical maturation in human term pregnancy2017
- Author(s)
  Samejima Taiki、Nagamatsu Takeshi、Schust Danny J.、Iriyama Takayuki、Sayama Seisuke、Sonoda Masaki、Komatsu Atsushi、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 78 Issue: 5
- DOI
  10.1111/aji.12711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10661
[Journal Article] Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor2017
- Author(s)
  Fujii Tatsuya、Nagamatsu Takeshi、Morita Kazuki、Schust Danny J.、Iriyama Takayuki、Komatsu Atsushi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12455-12455
- DOI
  10.1038/s41598-017-12685-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04979, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-16H06266, KAKENHI-PROJECT-16K15700
[Journal Article] 【産婦人科診療で用いられるバイオマーカー】早産マーカー2017
- Author(s)
  鮫島大輝, 永松健
- Journal Title
  
  . 産婦人科の実際
  
  Volume: 66 Pages: 1241-1245
- Data Source
  KAKENHI-PROJECT-15K10661
[Journal Article] A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro2017
- Author(s)
  Kenichiro Motomura, Naoko Okada, Hideaki Morita, Mariko Hara, Masato Tamari, Keisuke Orimo, Go Matsuda, Ken-Ichi Imadome, Akio Matsuda, Takeshi Nagamatsu, Mikiya Fujieda, Haruhiko Sago, Hirohisa Saito, and Kenji Matsumoto
- Journal Title
  
  PLOS ONE
  
  Volume: in press Issue: 5 Pages: e0177994-e0177994
- DOI
  10.1371/journal.pone.0177994
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21655, KAKENHI-PROJECT-17K10116, KAKENHI-PROJECT-17K11500, KAKENHI-PROJECT-17K18404, KAKENHI-PROJECT-15H04979, KAKENHI-PROJECT-15K09468, KAKENHI-PROJECT-17K10166
[Journal Article] 妊娠高血圧症候群の新知見 Preeclampsiaの胎盤機能障害　リゾリン脂質シグナルシステムからの視点2016
- Author(s)
  永松　健
- Journal Title
  
  日本周産期・新生児医学会雑誌
  
  Volume: 52 Pages: 434-434
- Data Source
  KAKENHI-PROJECT-15H04979
[Journal Article] Elevated concentration of secretory leukocyte protease inhibitor in the cervical mucus before delivery.2016
- Author(s)
  Samejima T, Nagamatsu T, Schust DJ, Itaoka N, Iriyama T, Nakayama T, Komatsu A, Kawana K, Osuga Y, Fujii T.
- Journal Title
  
  American Journal of Obstetrics and Gynecology
  
  Volume: 214 Issue: 6 Pages: 741.e1-741.e7
- DOI
  10.1016/j.ajog.2015.12.029
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10661
[Journal Article] Placental autotaxin expression is diminished in women with pre-eclampsia2015
- Author(s)
  Ichikawa M, Nagamatsu T, Schust DJ, Kawai-Iwasawa Y, Kawana K, Yamashita T, Osuga Y, Aoki J, Yatomi Y, Fujii T
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 41 Issue: 9 Pages: 1406-11
- DOI
  10.1111/jog.12742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253040, KAKENHI-PROJECT-15H04979
[Journal Article] Cervical Expression of Elafin and SLPI in Pregnancy and Their Association With Preterm Labor2015
- Author(s)
  Itaoka N, Nagamatsu T, Schust DJ, Ichikawa M, Sayama S, Iwasawa-Kawai Y, Kawana K, Yamashita T, Osuga Y, Fujii T.
- Journal Title
  
  American journal of reproductive immunology
  
  Volume: 未定 Issue: 6 Pages: 536-544
- DOI
  10.1111/aji.12354
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791688
[Journal Article] 妊娠維持と胎盤・脱落膜細胞によるT細胞制御2011
- Author(s)
  永松健
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56 Pages: 374-380
- Data Source
  KAKENHI-PROJECT-22890045
[Journal Article] Does the classical M1/M2 dichotomy reflect the functional phenotypes of human decidual macrophages2011
- Author(s)
  Danny J Schust, Takeshi Nagamatsu
- Journal Title
  
  Expert Review of Obstetrics & Gynecology
  
  Volume: 6 Issue: 4 Pages: 377-380
- DOI
  10.1586/eog.11.34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890045
[Journal Article] The regulation of T-cell cytokine production by ICOS-B7H2 interactions at the human fetomaternal interface2011
- Author(s)
  Nagamatsu T, Barrier BF, Schust DJ
- Journal Title
  
  Immunol Cell Biol
  
  Volume: 89 Issue: 3 Pages: 417-425
- DOI
  10.1038/icb.2010.101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890045
[Journal Article] Chlamydia trachomatis immune evasion via downregulation of MHC class I surface expression involves direct and indirect mechanisms2011
- Author(s)
  Ibana JA, Schust DJ, Sugimoto J, Nagamatsu T, Greene SJ, Quayle AJ
- Journal Title
  
  Infect Dis Obstet Gynecol
  
  Volume: 2011 Pages: 420905-420905
- DOI
  10.1155/2011/420905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890045
[Journal Article] The Contribution of Macrophages to Normal and Pathological Pregnancies2010
- Author(s)
  Nagamatsu T, Schust DJ
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 63 Issue: 6 Pages: 460-471
- DOI
  10.1111/j.1600-0897.2010.00813.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] Exploration of hidden factor X behind placental dysfunction in preeclampsia -insight into novel therapy2023
- Author(s)
  Takeshi Nagamatsu
- Organizer
  Korean Society of Reproductive Immunology 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09442
[Presentation] トロンボモジュリンの作用に着目した妊娠高血圧腎症への新規治療戦略2022
- Author(s)
  永松　健
- Organizer
  第37回日本生殖免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09442
[Presentation] Molecular Mechanisms Behind Placental Dysfunction in Preeclampsia - Insight Into Novel Therapeutic Approach-2021
- Author(s)
  Takeshi Nagamatsu
- Organizer
  The 11th The Singapore International Congress of Obstetrics & Gynaecology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09442
[Presentation] Obstetrics APSの免疫学的病理機序と治療法における課題ー抗血小板/抗凝固療法の先へ2021
- Author(s)
  永松　健
- Organizer
  第49回日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K09442
[Presentation] 子宮腺筋症病巣除去術後妊娠の周産期予後に関する検討2020
- Author(s)
  永松健
- Organizer
  第2回学術講演会　子宮腺筋症の妊孕性温存を考える会
- Data Source
  KAKENHI-PROJECT-19K22678
[Presentation] 妊娠高血圧症候群において酸化ストレスはNrf2シグナルを介してオートタキシン(ATX)の発現を促す2020
- Author(s)
  柳澤愛実、永松健、西森裕美子、藤井達也、利光正岳、佐山晴亮、瀬山貴博、熊澤恵一、入山高行、大須賀穣、藤井知行
- Organizer
  第35回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Light elevation underlies sflt-1 overproduction in hydatidiform mole: An implication for the pathogenic link between molar pregnancy and preeclampsia.2019
- Author(s)
  Matsui H, Iriyama T, Yoshikawa M, Niimi K, Yamamoto E, Kotani T, Nagamatsu T, Koga K, Osuga Y, Fujii T.
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Shifting of hif subtypes expression during syncytialization is associated with the regulation of vegf family molecules in human trophoblast cells.2019
- Author(s)
  Fujii T, Nagamatsu T, Morita K, Iriyama T, Osuga Y, Fujii T.
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Progranulin and secretory leukocyte protease inhibitor as key mediators in cervical ripening2019
- Author(s)
  Akiba Naoya, Takeshi Nagamatsu 他
- Organizer
  第71回日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] Regulation of cervical ripening by anti-inflammatory mediators in preterm labor and term delivery2019
- Author(s)
  Takeshi Nagamatsu
- Organizer
  The 14th World Congress of International Society for Immunology of Reproduction
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] The Development of Placenta Targeting Simvastatin Nano-Micelle Treatment in PE Mouse Model -Challenge for Clinical Application of Drug Delivery System to Avoid Adverse Effect on Fetus During Pregnancy2019
- Author(s)
  Hiroko Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii, Takuya Miyazaki, Horacio Cabral
- Organizer
  Japan Society of Obstetrics and Gynecology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179
[Presentation] Atx-lpaシステムの胎盤内酸化ストレス調節への寄与に関する検討.2019
- Author(s)
  柳澤愛実, 永松健, 西森裕美子, 三角史, 三村暢子, 秋葉直也, 入山高行, 熊澤惠一, 大須賀穣, 藤井知行
- Organizer
  第40回日本妊娠高血圧学会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] The development of placenta targeting simvastatin nano-micelle treatment in the mouse model of preeclampsia: Challenge for clinical application of drug delivery system to avoid the adverse effect on fetus during pregnancy.2019
- Author(s)
  Oda H, Nagamatsu T, Kumasawa K, Iriyama T, Osuga Y, Fujii T.
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Attenuation of Angiotensin II-Induced Preeclamptic Symptoms by Recombinant Thrombomodulin in Mice - a novel therapeutic approach for preeclampsia2018
- Author(s)
  Hiroko Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  Congress of the International Society of Hypertension in Pregnancy (ISSHP) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Secretory leukocyte protease inhibitor as a key regulator of cervical maturation2018
- Author(s)
  Takeshi Nagamatsu
- Organizer
  The 38th Annual Meeting of the American Society for reproductive Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] The association of progranulin expression controlled by progesterone with cervical maturation2018
- Author(s)
  Taiki Samejima, Takeshi Nagamatsu, Takayuki Iriyama, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第70回　日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] Progranulinによる頸管熟化制御機構-Essential role of progranulin in the regulation of cervical remodeling2018
- Author(s)
  秋葉　直也, 永松　健, 鮫島　大輝, 熊澤　恵一, 瀬山　貴博,　中山　敏男, 入山　高行, 大須賀　穣, 藤井　知行
- Organizer
  第33回日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] Drug delivery system to regulate placental transfer using nano-micelle technology to avoid harmful effect on the fetus2018
- Author(s)
  Takeshi Nagamatsu
- Organizer
  Congress of International Federation of Placental Association 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] 学術奨励賞受賞講演絨毛細胞機能および子宮頸管熟化を制御する分子システムと妊娠維持機構2018
- Author(s)
  永松　健
- Organizer
  第70回　日本産科婦人科学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] Placental autotaxin as a regulatory factor of placental function and fetal growth2018
- Author(s)
  Takeshi Nagamatsu
- Organizer
  The 20th Congress of Federation of Asia and Oceania Perinatal Societies (FAOPS)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] Progranulin as a key mediator in cervical ripening2018
- Author(s)
  Naoya Akiba,Takeshi Nagamatsu,Keiichi Kumasawa, Takayuki Iriyama, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  Congress of European Society for Reproductive Immunology 2018
- Data Source
  KAKENHI-PROJECT-18K09220
[Presentation] Serum autotaxin level as a biomarker to reflect placental function2018
- Author(s)
  Yumiko Nishimori, Takeshi Nagamatsu, Tatsuya Fujii, Nobuko Mimura, Takayuki Iriyama, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第70回日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] 学術奨励賞受賞講演　絨毛細胞機能および子宮頸管熟化を制御する分子システムと妊娠維持機構2018
- Author(s)
  永松　健
- Organizer
  第70回日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02943
[Presentation] 末梢血オートタキシン濃度は胎盤機能を反映する.2017
- Author(s)
  西森裕美子, 永松健, 藤井知行,他:
- Organizer
  日本生殖免疫学会
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Enhanced LPA-LPAR3 signaling under high oxidative stress environment in human placenta and its relevance to the pathoetiology of preeclampsia.2017
- Author(s)
  Tatsuya Fujii, Takeshi Nagamatsu, Mayuko Ichiikawa-Matsubara, Takayuki Iriyama, Atsushi Komatsu, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第69回日本産科婦人科学会学術講演会
- Place of Presentation
  広島、広島
- Year and Date
  2017-04-13
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Relation between level of edema and light scattering signal for the brain in a hypoxic ischemic encephalopathy model rat2017
- Author(s)
  Sakiko Kinoshita, Takeshi Nagamatsu, Takayuki Iriyama, Atsushi Komatsu,
- Organizer
  第69回日本産科婦人科学会学術集会
- Place of Presentation
  広島、広島
- Year and Date
  2017-04-14
- Data Source
  KAKENHI-PROJECT-15K15595
[Presentation] LPAR3 signaling is possibly involved in the clearance of oxidative stress in preeclamptic placenta.2017
- Author(s)
  Fujii T, Nagamatsu T,他,
- Organizer
  日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Preeclampsiaの胎盤機能障害－リゾリン脂質シグナルシステムからの視点2016
- Author(s)
  永松　健
- Organizer
  第52回日本周産期新生児医学会学術集会　シンポジウム
- Place of Presentation
  富山、富山
- Year and Date
  2016-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Enhanced expression of LPARs in preeclamptic placentas2016
- Author(s)
  Tatsuya Fujii, Takeshi Nagamatsu, Mayuko Itikawa-Matsubara, Takayuki Iriyama, Atsushi Komatsu, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京、東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Cervical SLPI expression during pregnancy is regulated by progesterone.2016
- Author(s)
  Taiki Samejima, Takeshi Nagamatsu, Toshio Nakayama, Takayuki Iriyama, Atsushi Komatsu, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術集会
- Place of Presentation
  中央区、東京
- Year and Date
  2016-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 複数遺伝子の発現プロファイルを用いた分娩前の子宮頸管熟化の評価と分娩発来予知法の検討2016
- Author(s)
  鮫島大輝、永松健、入山高行、川名敬、大須賀穣、藤井知行
- Organizer
  第31回日本生殖免疫学会
- Place of Presentation
  神戸、兵庫
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 新生仔ラット低酸素性虚血性脳障害モデルにおける光散乱信号の有用性2016
- Author(s)
  木下紗林, 永松健, 川内聡子, 佐藤俊一, 西舘泉, 藤井知行
- Organizer
  日本脳循環代謝学会
- Place of Presentation
  徳島、徳島
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K15595
[Presentation] 早産期の前期破水をどのように管理すべきか2016
- Author(s)
  永松　健
- Organizer
  千葉県産科婦人科医学会平成28年度秋季学術研修会
- Place of Presentation
  千葉、千葉
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] Preeclampsiaの胎盤機能障害－リゾリン脂質シグナルシステムからの視点2016
- Author(s)
  永松　健
- Organizer
  第52回　日本周産期新生児医学会学術集会
- Place of Presentation
  富山国際会議場・富山県民会館・ANAクラウンプラザホテル富山・富山市民プラザ（富山県・富山市）
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Cervical SLPI expression during pregnancy is regulated by progesterone.2016
- Author(s)
  Taiki Samejima, Takeshi Nagamatsu, Toshio Nakayama, Takayuki Iriyama, Atsushi Komatsu, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  中央区、東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] Monitoring of intrinsic optical signals relating to cerebral hemodynamics and cellular morphology in a rat hypoxic ischemic encephalopathy model2016
- Author(s)
  Sakiko Kinoshita, Takeshi Nagamatsu, Takayuki Iriyama, Atsushi Komatsu, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術集会
- Place of Presentation
  東京、東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15595
[Presentation] LPA-LPAR3システムの障害から見たPreeclampsiaの病態機序の解明2016
- Author(s)
  藤井達也　永松健　市川麻祐子　河合有希　川名敬　大須賀穣　藤井知行
- Organizer
  第31回日本生殖免疫学会総会・学術集会
- Place of Presentation
  神戸、兵庫
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Monitoring of intrinsic optical signals relating to cerebral hemodynamics and cellular morphology in a rat hypoxic ischemic encephalopathy model2016
- Author(s)
  Sakiko Kinoshita, Takeshi Nagamatsu, Takayuki Iriyama, Atsushi Komatsu, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都・千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15595
[Presentation] マウス早産モデルの子宮頸部におけるSLPI発現変化2015
- Author(s)
  鮫島大輝、永松健、板岡奈央、川名敬、大須賀穣、藤井知行
- Organizer
  第30回日本生殖免疫学会
- Place of Presentation
  熊本市、熊本
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 子宮頸管、卵膜の機能維持におけるSLPIの関与について2015
- Author(s)
  永松　健
- Organizer
  第20回病態プロテアーゼ学会
- Place of Presentation
  名古屋市、名古屋
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 頸管粘液中のα1MG、SLPI濃度上昇は陣痛発来予測因子となり得る－正期産妊婦における検討－2015
- Author(s)
  鮫島大輝、永松健、板岡奈央、佐山晴亮、小松篤史、川名敬、山下隆博、大須賀穣、藤井知行
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜市、神奈川
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 妊娠子宮の炎症制御におけるマクロファージの関与2015
- Author(s)
  永松　健
- Organizer
  第30回日本生殖免疫学会
- Place of Presentation
  くまもと県民交流館パレア（熊本県・熊本市）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] Alteration of LPA signaling in preeclamptic placenta2015
- Author(s)
  Tatsuya Fujii, Takeshi Nagamatsu, Mayuko Ichiikawa-Matsubara, Yuki Kawai-Iwasawa, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  12th World Congress of Perinatal Medicine
- Place of Presentation
  Madrid, Spain
- Year and Date
  2015-11-03
- Data Source
  KAKENHI-PROJECT-15H04979
[Presentation] SLPI in cervical mucus as a predictive marker for the labor onset.2015
- Author(s)
  Daiki Samejima, Takeshi Nagamatsu, Tomoyuki Fujii
- Organizer
  The 12th world congress of perinatal medicine
- Place of Presentation
  Madrid, Spain
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10661
[Presentation] 拡散反射分光法を用いた新生仔ラット低酸素性虚血性脳障害モデルのリアルタイム診断2015
- Author(s)
  木下紗林子、永松健、藤井知行、川内聡子、佐藤俊一、宮木麻衣、西舘泉
- Organizer
  第36回日本レーザ-医学会総会
- Place of Presentation
  栃木県総合文化センター（栃木県・宇都宮市）
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K15595
[Presentation] 妊娠中の子宮頸管におけるelafinとSLPIの生理的発現および切迫早産症例での変化ついての検討2013
- Author(s)
  板岡奈央、永松健、藤井知行、市川麻祐子、佐山晴亮、矢部慎一郎、川名敬、山下隆博、上妻志郎
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] Elafin and SLPI at the uterine cervix during human pregnancy as candidate molecular markers for preterm birth.2013
- Author(s)
  Nao ITAOKA, Takeshi NAGAMATSU, Mayuko ICHIKAWA,
- Organizer
  The 14th International Symposium for Immunology of Reproduction
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] 羊膜絨毛膜炎におけるelafinとSLPIの発現および発現誘導因子について2013
- Author(s)
  板岡奈央、永松健、市川麻祐子、佐山晴亮、河合有希、矢部慎一郎、川名敬、山下隆博、藤井知行
- Organizer
  第28回日本生殖免疫学会
- Place of Presentation
  西宮
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] 切迫早産の予後予測における顆粒球エラスターゼ検査の意義2012
- Author(s)
  森田一輝、永松健、堀越嗣博、兵藤博信、山下隆博、亀井良政、藤井知行、上妻志郎、武谷雄二
- Organizer
  第64回日本産科婦人科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] Expression and biological functions of Elafin and SLPI at the uterine cervix in the fetal membrane during　pregnancy2012
- Author(s)
  Nao ITAOKA, Takeshi NAGAMATSU, Tomoyuki FUJII
- Organizer
  The 20th FIGO World Congress of Gynecologic and Obstetrics
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] The regulation of T-cell activity by decidual cells via PD-1:B7-H1/-DC2011
- Author(s)
  Sayama S, Nagamatsu T
- Organizer
  15th International Congress of Mucosal Immunology
- Place of Presentation
  フランス、パリ(招待講演)
- Year and Date
  2011-07-07
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] The regulation of T-cell activity by decidual cells via PD-1 : B7-H1/-DC interaction2011
- Author(s)
  Sayama S, Nagamatsu T, Yamashita A, Kojima S, Tomio K, Kawana K, Fujii T, Kouzuma S, Taketani Y
- Organizer
  15^<th> Internationl Congress of Mucosal Immunology
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-07
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] Feto-Maternal Immunologic Interactions Mediated By Inducible Costimulator(ICOS) Signaling2010
- Author(s)
  Nagamatsu T, Barrier BF, Schust DJ
- Organizer
  66^<th> American Society for Reproductive Medicine Annual Meeting
- Place of Presentation
  Denver, USA
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] Feto-Maternal Immunologic Interactions Mediated By Inducible Costimulator (ICOS) Signaling2010
- Author(s)
  Takeshi Nagamatsu
- Organizer
  American Society for Reproductive Medicine Annual Meeting
- Place of Presentation
  Denver, Corolado, USA
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] Decidual stromal cells suppress T cell activation via IDO and costimulatory pathways2010
- Author(s)
  Nagamatsu T, Fujii T, Sayama S, Kawana K, Hyodo H, Yamashita T, Schust DJ, Kozuma S, Taketani Y
- Organizer
  International Symposium for Immunology of Reproduction/25^<th> Annual meeting of Japan Society for Immunology of Reproduction
- Place of Presentation
  Osaka, JAPAN
- Data Source
  KAKENHI-PROJECT-22890045
[Presentation] 絨毛膜羊膜炎における抗菌ペプチドelafinの発現および発現誘導因子について
- Author(s)
  板岡奈央、永松健、市川麻祐子、佐山晴亮、河合有希、矢部慎一郎、川名敬、山下隆博、大須賀穣、藤井知行
- Organizer
  第66回日本産科婦人科学会
- Place of Presentation
  東京
- Year and Date
  2014-04-18 – 2014-04-20
- Data Source
  KAKENHI-PROJECT-24791688
[Presentation] 頸管粘液中のα1MG、SLPI濃度上昇は陣痛発来予測因子となり得る－正期産妊婦における検討－
- Author(s)
  鮫島大輝、永松健、板岡奈央、佐山晴亮、小松篤史、川名敬、山下隆博、大須賀穣、藤井知行
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  横浜
- Year and Date
  2015-04-10 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-24791688
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1. Fujii Tomoyuki (40209010)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
2. 廣田泰 (40598653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Cabral Horacio (10533911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Yamashita Aki (00567448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAWANA Kei (60311627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 持田祐希 (60739134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAMEJIMA Taiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIMURA Nobuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. INOUE Eri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATOU Masakazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 矢富裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 市瀬茉里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 井上直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 本村健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagamatsu Takeshi 永松 健

NAGAMATSU Takeshi 永松 健

Research Projects

Research Products

Co-Researchers

胚低栄養環境による成人病発症の機序解明と妊娠母体への栄養介入による発症抑制法開発Principal Investigator

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The pathogenesis of preeclampsia focusing on the vascular endothelial dysfunction by HMGB1 and the search for new therapeutic agents.Principal Investigator

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Development of drug delivery system using nano-micelle carrier targeting placenta complicated with preeclampsia

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Development of novel approach for prevention of preterm birth by inhibiting cervical ripening using anti-inflammatory proteinsPrincipal Investigator

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Application of nanomedicine therapy for hypertensive disorders of pregnancy focusing on the molecular mechanisms related to oxidative stress regulation the placenta

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Development of a nano-pharmaceutical strategy for safely and effectively treating pregnant cancer patients

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The study about omega-3 fatty acids and their metabolites as preventive drugs for premature birth

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Study on molecular mechanism of cervical maturation focusing on anti-protease systemPrincipal Investigator

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Development of novel real time monitaring for fetal brain metabolism using diffuse reflectance

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Regulatory mechanism of microenvironment at fetomaternal interface by lipid mediators and progesterone

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Immulogogical system mediated by antimicropeptide at the uterine cervixPrincipal Investigator

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Basic Study of functionality and cell differentiation of decidual macrophages targeting the development of novel clinical approach for the prediction and the therapy of preterm delivery.Principal Investigator

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[Journal Article] Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia2024

Author(s)

Journal Title

Nagamatsu Takeshi 永松健

NAGAMATSU Takeshi 永松健

[Journal Article] 疾患と検査値の推移　妊娠高血圧症候群.2020