HISANO Yu 久野悠

Researcher Number	60467636
Affiliation (based on the past Project Information) *help	2015 – 2016: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 基礎科学特別研究員 2013: 独立行政法人理化学研究所, 生命システム研究センター, 特別研究員 2012: 独立行政法人理化学研究所, 循環器分子動態研究ユニット, 特別研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences
Keywords	Principal Investigator ゼブラフィッシュ / CRISPR/Cas9 system / TALEN / ゲノム編集 / 輸送体 / スフィンゴシン1リン酸 / 脂質メディエーター / CRISPR/Cas9 / ヌクレアーゼ / 逆遺伝学 … More / ノックイン / 人工ヌクレアーゼ / SPNS2 / 血管内皮細胞 / リンパ球 / トランスポーター / S1P Less

development of genome-editing techniques using engineered nucleasesPrincipal Investigator
- Principal Investigator
  
  Hisano Yu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Institute of Physical and Chemical Research
新規S1P輸送体によって制御される新たなS1Pの生理機能の解明Principal Investigator
- Principal Investigator
  
  久野悠
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of physiological roles of sphingosine-1-phosphate transporter, SPNS2Principal Investigator
- Principal Investigator
  
  HISANO Yu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Institute of Physical and Chemical Research

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 実験医学「新しい創薬標的としての脂質メディエーター分泌輸送体」2016
- Author(s)
  西毅、久野悠、小林直木、山口明人
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26460088
[Book] 医学のあゆみ「生命を支える脂質―最新の研究と臨床」2014
- Author(s)
  久野悠、川原敦雄
- Total Pages
  282
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PUBLICLY-25116722
[Book] 今すぐ始めるゲノム編集-TALEN＆CRISPR/Cas9の必須知識と実験プロトコール2014
- Author(s)
  木下政人、安齋賢、久野悠、川原敦雄
- Total Pages
  202
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26460088
[Book] 今すぐ始めるゲノム編集-TALEN＆CRISPR/Cas9の必須知識と実験プロトコール2014
- Author(s)
  木下政人、安齋賢、久野悠、川原敦雄
- Total Pages
  202
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-25116722
[Book] 実験医学別冊「今すぐ始めるゲノム編集」2014
- Author(s)
  木下政人、安齋賢、久野悠、川原敦雄
- Total Pages
  205
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790075
[Book] 医学のあゆみ「生命を支える脂質―最新の研究と臨床」2014
- Author(s)
  久野悠、川原敦雄
- Total Pages
  284
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24790075
[Book] 最新生理活性脂質研究とその臨床・創薬応用研究2013
- Author(s)
  久野悠、川原敦雄
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24790075
[Book] 最新生理活性脂質研究―実験手法、基礎的知識とその応用―2013
- Author(s)
  久野悠、川原敦雄
- Total Pages
  304
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PUBLICLY-25116722
[Book] 遺伝子医学MOOK「最新生理活性脂質研究」2013
- Author(s)
  久野悠、川原敦雄
- Total Pages
  304
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24790075
[Journal Article] Site-Specific Integration of Exogenous Genes Using Genome Editing Technologies in Zebrafish2016
- Author(s)
  Atsuo Kawahara, Yu Hisano, Satoshi Ota, Kiyohito Taimatsu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 17 Issue: 5 Pages: 727-727
- DOI
  10.3390/ijms17050727
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460088
[Journal Article] Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish.2015
- Author(s)
  Hisano Y, Sakuma T, Nakade S, Ohga R, Ota S, Okamoto H, Yamamoto T, Kawahara A.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 8841-8841
- DOI
  10.1038/srep08841
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23120008, KAKENHI-PUBLICLY-25116722, KAKENHI-PROJECT-25890014, KAKENHI-PROJECT-26460088, KAKENHI-PROJECT-26640064, KAKENHI-PROJECT-13J04914, KAKENHI-PROJECT-26870845
[Journal Article] Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish.2015
- Author(s)
  Hisano Y, Inoue A, Okudaira M, Taimatsu K, Matsumoto H, Kotani H, Ohga R, Aoki J, Kawahara A.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 24 Pages: 14841-14851
- DOI
  10.1074/jbc.m114.634717
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460088, KAKENHI-PROJECT-26640064
[Journal Article] Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis.2015
- Author(s)
  Hisano Y, Inoue A, Taimatsu K, Ota S, Ohga R, Kotani H, Muraki M, Aoki J, Kawahara A
- Journal Title
  
  Genes Cells.
  
  Volume: 20 Issue: 8 Pages: 647-658
- DOI
  10.1111/gtc.12259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460088, KAKENHI-PROJECT-13J04914, KAKENHI-PROJECT-26640064, KAKENHI-PROJECT-26870845
[Journal Article] Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering2014
- Author(s)
  Kimura, Y., Hisano, Y., Kawahara, A., and Higashijima, S.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 6545-6545
- DOI
  10.1038/srep06545
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23300123, KAKENHI-PUBLICLY-25116722, KAKENHI-PROJECT-26460088, KAKENHI-PROJECT-26640064, KAKENHI-PROJECT-26830025, KAKENHI-PUBLICLY-25115735, KAKENHI-PROJECT-26290013
[Journal Article] Genome editing using artificial site-specific nucleases in zebrafish2014
- Author(s)
  Yu Hisano, Satoshi Ota and Atsuo Kawahara
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 56 Issue: 1 Pages: 26-33
- DOI
  10.1111/dgd.12094
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04914, KAKENHI-PROJECT-24790075, KAKENHI-PUBLICLY-25116722
[Journal Article] Molecular and physiological functions of sphingosine 1-phosphate transporters2014
- Author(s)
  Nishi, T., Kobayashi, N., Hisano, Y., Kawahara, A. and Yamaguchi, A
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1841 Issue: 5 Pages: 759-765
- DOI
  10.1016/j.bbalip.2013.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790093, KAKENHI-PROJECT-24790075, KAKENHI-PUBLICLY-25116722, KAKENHI-PROJECT-25670024, KAKENHI-PROJECT-25870695, KAKENHI-PROJECT-26460088
[Journal Article] Multiple genome modifications by the CRISPR/Cas9 system in zebrafish.2014
- Author(s)
  Ota S, Hisano Y, Ikawa Y, Kawahara A.
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790075
[Journal Article] Multiple genome modifications by the CRISPR/Cas9 system in zebrafish2014
- Author(s)
  Satoshi Ota, Yu Hisano, Yohshiya Ikawa, Atsuo Kawahara
- Journal Title
  
  Genes to Cells
  
  Volume: 19 Issue: 7 Pages: 555-564
- DOI
  10.1111/gtc.12154
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04914, KAKENHI-PUBLICLY-25116722, KAKENHI-PROJECT-26460088, KAKENHI-PROJECT-26640064, KAKENHI-PROJECT-26870845
[Journal Article] Functional cooperation of spns2 and fibronectin in cardiac and lower jaw development2013
- Author(s)
  Yu Hisano, Satoshi Ota, Shinji Takada and Atsuo Kawahara
- Journal Title
  
  Biology Open
  
  Volume: 2 Issue: 8 Pages: 789-794
- DOI
  10.1242/bio.20134994
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J04914, KAKENHI-PROJECT-23370094, KAKENHI-PROJECT-23657153, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111002, KAKENHI-PROJECT-24790075, KAKENHI-PUBLICLY-25116722
[Journal Article] Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays2013
- Author(s)
  Satoshi Ota, Yu Hisano, Michiko, Kazuyuki Hoshijima, Timothy J. Dahlem, David J. Grumwald, Yasushi Okada and Kawahara
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Issue: 6 Pages: 450-458
- DOI
  10.1111/gtc.12050
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J04914, KAKENHI-PROJECT-24790075, KAKENHI-PUBLICLY-25116722
[Journal Article] Quantitative assay for TALEN activity at endogenous genomic loci.2013
- Author(s)
  Hisano Y.
- Journal Title
  
  Biology Open
  
  Volume: BIO20133871 Issue: 4 Pages: 363-367
- DOI
  10.1242/bio.20133871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05012, KAKENHI-PROJECT-12J06938, KAKENHI-PROJECT-24790075
[Journal Article] Mouse SPNS2 functions as a sphingoshine 1-phosphate transporter in vascular endothelial cells2012
- Author(s)
  Hisano, Y., Kobayashi, N., Yamaguchi, A., Nishi T.
- Journal Title
  
  PloS ONE
  
  Volume: 7 Issue: 6 Pages: 38941-38941
- DOI
  10.1371/journal.pone.0038941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200071, KAKENHI-PROJECT-21570137, KAKENHI-PROJECT-23790093, KAKENHI-PROJECT-24790075
[Journal Article] The functional roles of S1P in immunity.2012
- Author(s)
  Hisano Y, Nishi T, Kawahara A.
- Journal Title
  
  J Biochem.
  
  Volume: 152 Issue: 4 Pages: 305-311
- DOI
  10.1093/jb/mvs090
- NAID
  10031166143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570137, KAKENHI-PROJECT-24790075
[Journal Article] Multiple genome modifications by the CRISPR/Cas9 system in zebrafish
- Author(s)
  Satoshi Ota, Yu Hisano, Yoshiya Ikawa, Atsuo Kawahara
- Journal Title
  
  Genes to Cells
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Spatial proteomics analysis for identifying sphingosine 1-phosphate receptor- associated proteins on endothelial cells2016
- Author(s)
  Hisano Y, Obinata H, Hla T.
- Organizer
  19th International Vascular Biology Meeting
- Place of Presentation
  ボストン
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Genome modifications by the CRISPR/Cas9 system in zebrafish.2014
- Author(s)
  Hisano Y, Ota S, Kawahara A.
- Organizer
  2nd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Precise genome-editing using CRISPR/Cas9 system2014
- Author(s)
  Hisano Y, Ota S, Okamoto H, Kawahara A.
- Organizer
  20th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  東京　慶應義塾大学薬学部（芝共立キャンパス）
- Year and Date
  2014-09-21
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Genome modifications by the CRISPR/Cas9 system in zebrafish2014
- Author(s)
  Yu Hisano
- Organizer
  2nd"International Institute for Advanced Studies"Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都
- Year and Date
  2014-02-27
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Genome modifications by the CRISPR/Cas9 system in zebrafish.2014
- Author(s)
  Hisano Y, Ota S, Kawahara A.
- Organizer
  2nd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Functional analysis of sphingosine-1-phosphate (S1P) signaling using S1PRs knockout fish2013
- Author(s)
  Yu Hisano
- Organizer
  8th European Zebrafish Meeting
- Place of Presentation
  Barcelona、Spain
- Year and Date
  2013-07-11
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Generation and analysis of S1P receptors-deficient zebrafish using TALEN.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  FASEB Science Research Conference “Lysophospholipid and Other Related mediators-From Bench to Clinic”
- Place of Presentation
  北海道ニセコプリンスホテル
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] TALEN-mediated gene disruption for analyzing S1P signaling in zebrafish.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  19th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  仙台AERビル
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Functional analysis of sphingosine-1-phosphate (S1P) signaling using S1PRs knockout fish.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  8th European Zebrafish Meeting
- Place of Presentation
  スペイン、バルセロナ
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] TALEN-mediated gene disruption for analyzing S1P signaling in zebrafish2013
- Author(s)
  Yu Hisano
- Organizer
  19th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  仙台
- Year and Date
  2013-09-20
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] TALENを用いたS1P受容体ノックアウトフィッシュの作製2013
- Author(s)
  久野悠
- Organizer
  「自然炎症」「脂質マシナリー」合同若手ワークショップ
- Place of Presentation
  徳島
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] TALEN-mediated gene disruption for analyzing S1P signaling in zebrafish.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  19th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  仙台AERビル
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Generation and analysis of S1P receptors-deficient zebrafish using TALEN2013
- Author(s)
  Yu Hisano
- Organizer
  FASEB Science Research Conference"Lysophospholipid and Other Related mediators-From Bench to Clinic
- Place of Presentation
  ニセコ
- Year and Date
  2013-08-06
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Generation and analysis of S1P receptors-deficient zebrafish using TALEN.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  FASEB Science Research Conference “Lysophospholipid and Other Related mediators-From Bench to Clinic”
- Place of Presentation
  北海道ニセコプリンスホテル
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Functional analysis of sphingosine-1-phosphate (S1P) signaling using S1PRs knockout fish.2013
- Author(s)
  Hisano Y, Ota S, Muraki M, Kawahara A.
- Organizer
  8th European Zebrafish Meeting
- Place of Presentation
  スペイン、バルセロナ
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] ゼブラフィッシュにおけるTALENによる遺伝子改変技術の開発2012
- Author(s)
  久野悠
- Organizer
  第二回ゲノム編集研究会
- Place of Presentation
  岡崎
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] ゼブラフィッシュにおけるTALENによる遺伝子改変技術の開発2012
- Author(s)
  久野悠, 太田聡, 村木倫子, 岡田康志, 川原敦雄
- Organizer
  第２回ゲノム編集研究会
- Place of Presentation
  岡崎コンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] 分泌輸送体及び受容体を介したS1Pシグナリングの生理的役割の解析2012
- Author(s)
  久野悠、太田聡、村木倫子、川原敦雄
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Roles of S1P signaling during early embryogenesis2012
- Author(s)
  Satoshi Ota, Michiko Ueno, Yu Hisano, Atsuo Kawahara
- Organizer
  10th International Conference on Zebrafish Development and Genetics
- Place of Presentation
  USA Wisconsin
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] S1Pシグナリング関連分子破壊ゼブラフィッシュの作成2012
- Author(s)
  久野悠
- Organizer
  新学術領域研究「脂質マシナリー」第3回班会議
- Place of Presentation
  秋田
- Year and Date
  2012-11-13
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] 分泌輸送体及び受容体を介したS1Pシグナリングの生理的役割の解析2012
- Author(s)
  久野悠
- Organizer
  第85回日本生化学会大会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] TALEN-mediated genome editing in zebrafish2012
- Author(s)
  Satoshi Ota1, Yu Hisano1, Michiko Muraki1, Tetsushi Sakuma2, Takashi Yamamoto2, Yasushi Okada1 and Atsuo Kawahara1
- Organizer
  18th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  京都大学
- Data Source
  KAKENHI-PROJECT-24790075
[Presentation] Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering
- Author(s)
  Kimura Y, Hisano Y, Kawahara A, Higashijima S.
- Organizer
  The 3rd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Year and Date
  2014-10-28 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering
- Author(s)
  Kimura Y, Hisano Y, Kawahara A, Higashijima S.
- Organizer
  20th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  東京　慶應義塾大学薬学部（芝共立キャンパス）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Exogenous DNA integration into zebrafish genome without indel mutations at the junctions
- Author(s)
  Hisano Y, Okamoto H, Kawahara A.
- Organizer
  The 3rd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Year and Date
  2014-10-28 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Exogenous DNA integration into zebrafish genome without indel mutations at the junctions
- Author(s)
  Hisano Y, Okamoto H, Kawahara A.
- Organizer
  The 3rd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Year and Date
  2014-10-28 – 2014-10-29
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering
- Author(s)
  Kimura Y, Hisano Y, Kawahara A, Higashijima S.
- Organizer
  The 3rd “International Institute for Advanced Studies” Conference of Novel Developments on the Study of Life and Biological Systems Based on Genome Engineering and Imaging Science
- Place of Presentation
  京都国際高等研究所
- Year and Date
  2014-10-28 – 2014-10-29
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Precise genome-editing using CRISPR/Cas9 system
- Author(s)
  Hisano Y, Ota S, Okamoto H, Kawahara A.
- Organizer
  20th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  東京　慶應義塾大学薬学部（芝共立キャンパス）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Loss-of-function analysis of S1P signaling molecules in zebrafish.
- Author(s)
  Kotani H, Hisano Y, Inoue A, Okudaira M, Ohga R, Okamoto H, Aoki H, Kawahara A.
- Organizer
  6th International Conference on Phospholipase A2 and Lipid Mediators (PLM2015)
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-26460088
[Presentation] Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering
- Author(s)
  Kimura Y, Hisano Y, Kawahara A, Higashijima S.
- Organizer
  20th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  東京　慶應義塾大学薬学部（芝共立キャンパス）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] Loss-of-function analysis of S1P signaling molecules in zebrafish.
- Author(s)
  Kotani H, Hisano Y, Inoue A, Okudaira M, Ohga R, Okamoto H, Aoki H, Kawahara A.
- Organizer
  6th International Conference on Phospholipase A2 and Lipid Mediators (PLM2015)
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] CRISPR/Cas9 systemを利用した遺伝子挿入ゼブラフィッシュの作製
- Author(s)
  久野悠、太田聡、岡本仁、川原敦雄
- Organizer
  第４回ゲノム編集研究会
- Place of Presentation
  広島国際会議場ダリア
- Year and Date
  2014-10-06 – 2014-10-07
- Data Source
  KAKENHI-PUBLICLY-25116722
[Presentation] CRISPR/Cas9 systemを利用した遺伝子挿入ゼブラフィッシュの作製
- Author(s)
  久野悠、太田聡、岡本仁、川原敦雄
- Organizer
  第４回ゲノム編集研究会
- Place of Presentation
  広島国際会議場ダリア
- Year and Date
  2014-10-06 – 2014-10-07
- Data Source
  KAKENHI-PROJECT-26460088

1. KAWAHARA Atsuo (10362518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. KOBAYASHI Takuma (80582288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NISHI Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 東島眞一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 小林直木

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 岡本仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HISANO Yu 久野 悠

Research Projects

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Co-Researchers

development of genome-editing techniques using engineered nucleasesPrincipal Investigator

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新規S1P輸送体によって制御される新たなS1Pの生理機能の解明Principal Investigator

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Analysis of physiological roles of sphingosine-1-phosphate transporter, SPNS2Principal Investigator

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[Book] 実験医学「新しい創薬標的としての脂質メディエーター分泌輸送体」2016

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[Book] 医学のあゆみ「生命を支える脂質―最新の研究と臨床」2014

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[Book] 今すぐ始めるゲノム編集-TALEN＆CRISPR/Cas9の必須知識と実験プロトコール2014

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[Book] 今すぐ始めるゲノム編集-TALEN＆CRISPR/Cas9の必須知識と実験プロトコール2014

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[Book] 実験医学別冊「今すぐ始めるゲノム編集」2014

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[Book] 医学のあゆみ「生命を支える脂質―最新の研究と臨床」2014

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[Book] 最新生理活性脂質研究とその臨床・創薬応用研究2013

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[Book] 最新生理活性脂質研究―実験手法、基礎的知識とその応用―2013

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[Book] 遺伝子医学MOOK「最新生理活性脂質研究」2013

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[Journal Article] Site-Specific Integration of Exogenous Genes Using Genome Editing Technologies in Zebrafish2016

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[Journal Article] Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish.2015

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[Journal Article] Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish.2015

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HISANO Yu 久野悠