Jeelani Ghulam ＪｅｅｌａｎｉＧｈｕｌａｍ

Researcher Number	60468519
Other IDs	https://orcid.org/0000-0003-0816-9831
Affiliation (Current)	2026: 東京大学, 大学院医学系研究科(医学部), 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 49040:Parasitology-related Except Principal Investigator Basic Section 49040:Parasitology-related
Keywords	Principal Investigator Protozoan parasite / Metabolism / Entamoeba histolytica / Plasma membrane / GPI anchor / Stage conversion / GABA / Drug developement / Metabolisms / Polyamine / Drug development / Protozoan Parasite / polyamine pathway … More Except Principal Investigator … More 貧食 / 脂質輸送 / フォスファターゼ / キナーゼ / 受容体 / 病原機構 / 貪食 / 腸炎 / 赤痢アメーバ Less

Elucidation of biosynthesis, transportation, and physiological functions of GABA in Entamoeba histolyticaPrincipal Investigator
- Principal Investigator
  
  Jeelani Ghulam
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  The University of Tokyo
New Developments in the Parasitic Polyamine Biosynthetic Pathway Using Entamoeba histolytica as a ModelPrincipal Investigator
- Principal Investigator
  
  Jeelani Ghulam
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  The University of Tokyo
Analysis of molecular mechanism of trogocytosis in Entamoeba histolytica
- Principal Investigator
  
  Nozaki Tomoyoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Sealgamide: An Antitrypanosomal Lipopeptide Isolated from a Marine Okeania sp. Cyanobacterium2025
- Author(s)
  Wakai Kazuki、Kurisawa Naoaki、Umeda Kairi、Jeelani Ghulam、Agusta Adnan Luthfi、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Journal of Natural Products
  
  Volume: - Issue: 4 Pages: 1048-1056
- DOI
  10.1021/acs.jnatprod.5c00141
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K10185
[Journal Article] Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine Moorena sp. Cyanobacterium2025
- Author(s)
  Hagihara Masahiro、Kurisawa Naoaki、Iwasaki Arihiro、Taguchi Raimu、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Organic Letters
  
  Volume: 27 Issue: 5 Pages: 1261-1264
- DOI
  10.1021/acs.orglett.4c04832
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639, KAKENHI-PROJECT-24K08620, KAKENHI-PROJECT-24K10185, KAKENHI-PROJECT-24KJ1289
[Journal Article] Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis2024
- Author(s)
  Balogun Emmanuel Oluwadare、Joseph Gideon Ibrahim、Olabode Samuel Charles、Dayaso Naziru Abdulkadir、Danazumi Ammar Usman、Bashford-Rogers Rachael、Mckerrow James H.、Jeelani Ghulam、Caffrey Conor R.
- Journal Title
  
  Pathogens
  
  Volume: 13 Issue: 10 Pages: 850-850
- DOI
  10.3390/pathogens13100850
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10185
[Journal Article] Isolation and structure determination of a new analog of polycavernosides from marine Okeania sp. cyanobacterium2024
- Author(s)
 Umeda Kairi、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake、Iwasaki Arihiro
- Journal Title
 
 Beilstein Journal of Organic Chemistry
 
 Volume: 20 Pages: 645-652
- DOI
 10.3762/bjoc.20.57
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Therapeutic potential of Indonesian plant extracts in combating malaria and protozoan neglected tropical disease2024
- Author(s)
  Sari Defi Kartika、Jeelani Ghulam、Ilmi Hilkatul、Tumewu Lidya、Wahyuni Ratna、Widyawaruyanti Aty、Nozaki Tomoyoshi、Hafid Achmad Fuad
- Journal Title
  
  BMC Complementary Medicine and Therapies
  
  Volume: 24 Issue: 1 Pages: 416-416
- DOI
  10.1186/s12906-024-04717-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10185
[Journal Article] Wajeepeptin, a Cytotoxic and Antitrypanosomal Cyclic Depsipeptide from a Marine Moorena sp. Cyanobacterium2024
- Author(s)
  Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Agusta Adnan Luthfi、Suenaga Kiyotake、Iwasaki Arihiro
- Journal Title
  
  Journal of Natural Products
  
  Volume: 87 Issue: 7 Pages: 1838-1843
- DOI
  10.1021/acs.jnatprod.4c00499
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-24K01639, KAKENHI-PROJECT-24K10185
[Journal Article] Amantamide C, an Antitrypanosomal Linear Lipopeptide from a Marine Okeania sp. Cyanobacterium2024
- Author(s)
 Watanabe Natsumi、Jeelani Ghulam、Nozaki Tomoyoshi、Iwasaki Arihiro
- Journal Title
 
 ACS Omega
 
 Volume: 9 Pages: 36795-36801
- DOI
 10.1021/acsomega.4c05909
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-24K08620, KAKENHI-PROJECT-24K10185
[Journal Article] Pemuchiamides A and B, Proline-Rich Linear Lipopeptides, Isolated from a Marine Hormoscilla sp. Cyanobacterium2024
- Author(s)
 Irie Kensuke、Jeelani Ghulam、Nozaki Tomoyoshi、Iwasaki Arihiro
- Journal Title
 
 Journal of Natural Products
 
 Volume: 87 Issue: 9 Pages: 2292-2301
- DOI
 10.1021/acs.jnatprod.4c00733
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-24K08620, KAKENHI-PROJECT-24K10185
[Journal Article] Identification and characterization of archaeal-type FAD synthase as a novel tractable drug target from the parasitic protozoa Entamoeba histolytica2024
- Author(s)
 Wulansari Dewi、Jeelani Ghulam、Yazaki Euki、Nozaki Tomoyoshi
- Journal Title
 
 mSphere
 
 Volume: 9 Issue: 9
- DOI
 10.1128/msphere.00347-24
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-24K10185
[Journal Article] Kagimminols A and B, Cembrene-Type Diterpenes from an Okeania sp. Marine Cyanobacterium2024
- Author(s)
 Ebihara Akira、Taguchi Raimu、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake、Iwasaki Arihiro
- Journal Title
 
 Journal of Natural Products
 
 Volume: press Issue: 4 Pages: 1116-1123
- DOI
 10.1021/acs.jnatprod.4c00056
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870, KAKENHI-PROJECT-24KJ1289
[Journal Article] Isolation of Hennaminal and Isolation and Total Synthesis of Hennamide, Pyrrolinone Compounds from the Marine Cyanobacterium Rivularia sp.2023
- Author(s)
 Takahashi Hiroki、Iwasaki Arihiro、Ebihara Akira、Taguchi Raimu、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
 
 Organic Letters
 
 Volume: press Issue: 14 Pages: 2400-2404
- DOI
 10.1021/acs.orglett.3c00421
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-20H02870
[Journal Article] Total synthesis of acetylene-containing lipopeptides odookeanynes A and B2023
- Author(s)
  Lo Yung-Han、Umeda Kairi、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 130 Pages: 154763-154763
- DOI
  10.1016/j.tetlet.2023.154763
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Isolation and Structure Determination of Akunolides, Macrolide Glycosides from a Marine Okeania sp. Cyanobacterium2023
- Author(s)
 Umeda Kairi、Iwasaki Arihiro、Taguchi Raimu、Kurisawa Naoaki、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
 
 Journal of Natural Products
 
 Volume: 86 Issue: 11 Pages: 2529-2538
- DOI
 10.1021/acs.jnatprod.3c00742
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K19252, KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Attenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in Entamoeba histolytica2023
- Author(s)
  Lozano-Mendoza J, Ramirez-Montiel F, Rangel-Serrano A, Paramo-Perez I, Mendoza-Macias C, Saavedra-Salazar F, Franco B, Vargas-Maya N, Jeelani G, Saito-Nakano Y, Anaya-Velazquez F, Nozaki T, Padilla-Vaca F
- Journal Title
  
  Pathogens
  
  Volume: 12 Issue: 3 Pages: 489-489
- DOI
  10.3390/pathogens12030489
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07050, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-19K07531, KAKENHI-PROJECT-21KK0135, KAKENHI-PROJECT-21H02723
[Journal Article] Molecular identification of phlebotomine sand flies and the harbored Leishmania spp. in Sokoto State, Nigeria2023
- Author(s)
  Usman Mahmud、Natala Audu Joseph、Jatau Isa Danladi、Ogo Ndudim Isaac、Jeelani Ghulam、Goto Yasuyuki、Nozaki Tomoyoshi、McKerrow James H.、Balogun Emmanuel Oluwadare
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 13 Pages: 1219629-1219629
- DOI
  10.3389/fcimb.2023.1219629
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-21H02722
[Journal Article] Glycerol biosynthetic pathway plays an essential role in proliferation and antioxidative defense in the human enteric protozoan parasite Entamoeba histolytica.2023
- Author(s)
  Jeelani, G., Balogun, E. O., Husain, A., Nurkanto, A., Shiba, T., and Nozaki, T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 13(1) Issue: 1 Pages: 14596-14596
- DOI
  10.1038/s41598-023-40670-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19372, KAKENHI-PROJECT-21K15427
[Journal Article] PTEN differentially regulates endocytosis, migration, and proliferation in the enteric protozoan parasite Entamoeba histolytica.2022
- Author(s)
  Kadri S, Nakada-Tsukui K, Watanabe N, Jeelani G, Nozaki T.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 18 Issue: 5 Pages: 1010147-1010147
- DOI
  10.1371/journal.ppat.1010147
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19372, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-21KK0135, KAKENHI-PROJECT-21KK0139
[Journal Article] Transcriptome Analysis of Entamoeba histolytica Trophozoites during in vivo Contact-independent Mediated Host-parasite Interaction: Putative Pathways Related to PCD2022
- Author(s)
  Ishiwara David Guillermo P?rez、Shibayama Mineko、Nakada-Tsukui Kumiko、Jeelani Ghulam、G?mez-Garc?a Mar?a del Consuelo、Flores Olivia Medel、Nozaki Tomoyoshi
- Journal Title
  
  Microbiology Research Journal International
  
  Volume: 32 Pages: 42-62
- DOI
  10.9734/mrji/2022/v32i530390
- Data Source
  KAKENHI-PROJECT-21K15427
[Journal Article] Isolation and Total Synthesis of Beru’amide, an Antitrypanosomal Polyketide from a Marine Cyanobacterium Okeania sp.2022
- Author(s)
 Taguchi Raimu、Iwasaki Arihiro、Ebihara Akira、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
 
 Organic Letters
 
 Volume: 24 Issue: 25 Pages: 4710-4714
- DOI
 10.1021/acs.orglett.2c02013
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427, KAKENHI-PROJECT-20H02870
[Journal Article] Physiological roles and metabolism of γ-aminobutyric acid (GABA) in parasitic protozoa2022
- Author(s)
  Nugraha Rivo Yudhinata Brian、Jeelani Ghulam、Nozaki Tomoyoshi
- Journal Title
  
  Trends in Parasitology
  
  Volume: press Issue: 6 Pages: 462-477
- DOI
  10.1016/j.pt.2022.02.004
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15427
[Journal Article] Isolation and Total Synthesis of Bromoiesol sulfates, Antitrypanosomal arylethers from a Salileptolyngbya sp. Marine Cyanobacterium2021
- Author(s)
  Ebihara Akira、Iwasaki Arihiro、Miura Youhei、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 17 Pages: 11763-11770
- DOI
  10.1021/acs.joc.1c01214
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02870, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427
[Journal Article] Isolation and Total Synthesis of Kinenzoline, an Antitrypanosomal Linear Depsipeptide Isolated from a Marine Salileptolyngbya sp. Cyanobacterium2021
- Author(s)
  Kurisawa Naoaki、Otomo Keisuke、Iwasaki Arihiro、Jeelani Ghulam、Nozaki Tomoyoshi、Suenaga Kiyotake
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 18 Pages: 12528-12536
- DOI
  10.1021/acs.joc.1c00817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02870, KAKENHI-PROJECT-21J13608, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427
[Journal Article] First Total Synthesis and Structure-Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium2021
- Author(s)
  Iwasaki Arihiro、Teranuma Kazuya、Kurisawa Naoaki、Rahmawati Yulia、Jeelani Ghulam、Nozaki Tomoyoshi、Gerwick William H.、Suenaga Kiyotake
- Journal Title
  
  Journal of Natural Products
  
  Volume: 84 Issue: 9 Pages: 2587-2593
- DOI
  10.1021/acs.jnatprod.1c00792
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02870, KAKENHI-PROJECT-21J13608, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-21K15427
[Journal Article] Identification and Functional Characterization of Divergent 3’-Phosphate tRNA Ligase From Entamoeba histolytica2021
- Author(s)
  Peng Ruofan、Yoshinari Shigeo、Kawano-Sugaya Tetsuro、Jeelani Ghulam、Nozaki Tomoyoshi
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 746261-746261
- DOI
  10.3389/fcimb.2021.746261
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15427
[Presentation] Characterization of archaeal-type FAD synthase as a novel tractable drug target from the parasitic protozoa Entamoeba histolytica2024
- Author(s)
  GHULAM JEELANI
- Organizer
  35th Molecular Parasitology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10185
[Presentation] Metabolic Flexibility of Entamoeba histolytica: Galactose as an Alternative Energy Source2024
- Author(s)
  GHULAM JEELANI
- Organizer
  International meeting of Amebiasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10185
[Presentation] Exploring the Polyamine Pathway in Human Enteric Protozoan Parasite Entamoeba histolytica2024
- Author(s)
  GHULAM JEELANI
- Organizer
  48th FEBS Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10185
[Presentation] Metabolomic of parasite infectious diseases for identification potential drug target.2023
- Author(s)
  Jeelani Ghulam
- Organizer
  The 13th International Symposium of Indonesian Society for Microbiology.
- Invited
- Data Source
  KAKENHI-PROJECT-21K15427
[Presentation] Biochemical, structural and functional characterization of glycerol kinase from human enteric protozoan parasite Entamoeba histolytica.2019
- Author(s)
  Nozaki, T and Jeelani G.
- Organizer
  第92回日本生化学会大会シンポジウム構造生物学から見た寄生適応の分子戦略
- Data Source
  KAKENHI-PROJECT-18H02650

1. Nozaki Tomoyoshi (60198588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 栗澤尚瑛

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
3. 末永聖武

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 津久井久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中野由美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 岩崎有紘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Jeelani Ghulam Ｊｅｅｌａｎｉ Ｇｈｕｌａｍ

Research Projects

Research Products

Co-Researchers

Elucidation of biosynthesis, transportation, and physiological functions of GABA in Entamoeba histolyticaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New Developments in the Parasitic Polyamine Biosynthetic Pathway Using Entamoeba histolytica as a ModelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanism of trogocytosis in Entamoeba histolytica

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Sealgamide: An Antitrypanosomal Lipopeptide Isolated from a Marine Okeania sp. Cyanobacterium2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and Total Synthesis of Ukabamide, an Antitrypanosomal Lipopeptide from a Marine Moorena sp. Cyanobacterium2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation and structure determination of a new analog of polycavernosides from marine <i>Okeania</i> sp. cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic potential of Indonesian plant extracts in combating malaria and protozoan neglected tropical disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wajeepeptin, a Cytotoxic and Antitrypanosomal Cyclic Depsipeptide from a Marine Moorena sp. Cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amantamide C, an Antitrypanosomal Linear Lipopeptide from a Marine <i>Okeania</i> sp. Cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pemuchiamides A and B, Proline-Rich Linear Lipopeptides, Isolated from a Marine <i>Hormoscilla</i> sp. Cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and characterization of archaeal-type FAD synthase as a novel tractable drug target from the parasitic protozoa <i>Entamoeba histolytica</i>2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kagimminols A and B, Cembrene-Type Diterpenes from an <i>Okeania</i> sp. Marine Cyanobacterium2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation of Hennaminal and Isolation and Total Synthesis of Hennamide, Pyrrolinone Compounds from the Marine Cyanobacterium <i>Rivularia</i> sp.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Total synthesis of acetylene-containing lipopeptides odookeanynes A and B2023

Author(s)

Journal Title

Jeelani Ghulam ＪｅｅｌａｎｉＧｈｕｌａｍ