Miyanari Yusuke 宮成悠介

Researcher Number	60469608
Other IDs
Affiliation (Current)	2025: 金沢大学, ナノ生命科学研究所, 教授
Affiliation (based on the past Project Information) *help	2025: 金沢大学, ナノ生命科学研究所, 教授 2021 – 2025: 金沢大学, ナノ生命科学研究所, 准教授 2018 – 2020: 大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 特任准教授 2017: 大学共同利用機関法人自然科学研究機構(新分野創成センター), 生命創成探究センター, 特任准教授 2014 – 2016: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特任准教授
Review Section/Research Field	Principal Investigator Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Biological Sciences / Molecular biology / Morphology/Structure / Developmental biology Except Principal Investigator Basic Section 52040:Radiological sciences-related / Basic Section 63020:Radiation influence-related
Keywords	Principal Investigator クロマチン / エピジェネティクス / 遺伝学 / 転写 / ゲノム / 核内構造 / クロマチン構造 / PML / 転写制御 / PML body / 核内構造体 / ゲノム構造 / クロマチン高次構造 … More Except Principal Investigator … More ナノボディ / PROTACS / 膵臓がん / セラノスティクス / 転写 / DSB修復 / 染色体転座 / クロマチン / HR / NHEJ / 放射線 / DNA修復 / 放射性薬剤 / イメージング / 分子イメージング / 膵臓癌 / PET Less

細胞老化機構の理解と応用Principal Investigator
- Principal Investigator
  
  宮成悠介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Kanazawa University
In cell analysis of chromatin regulating complexesPrincipal Investigator
- Principal Investigator
  
  宮成悠介
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Development of theranostics agents combining nanobodies and PROTACs for pancreatic cancer
- Principal Investigator
  
  淵上剛志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Dissecting a transcriptional domainPrincipal Investigator
- Principal Investigator
  
  宮成悠介
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kanazawa University
全ゲノム領域に共通した正確なDNA修復を保証するDSB修復経路選択機構の研究
- Principal Investigator
  
  柴田淳史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Keio University
  Gunma University
Development of nanobody molecular probes for early diagnosis of pancreatic cancers
- Principal Investigator
  
  FUCHIGAMI Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Nagasaki University
Regulation of chromatin accessibilityPrincipal Investigator
- Principal Investigator
  
  宮成悠介
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
How to get transparency for generation of transparent animals.Principal Investigator
- Principal Investigator
  
  Miyanari Yusuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphology/Structure
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences
Uncovering roles of PML bodies in transcriptionPrincipal Investigator
- Principal Investigator
  
  Miyanari Yusuke
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
  Okazaki Research Facilities, National Institutes of Natural Sciences
クロマチンイメージングによって解き明かす転写制御機構Principal Investigator
- Principal Investigator
  
  宮成悠介
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Developmental biology
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences

All 2023 2022 2021 2020 2019 2018 2017 2016 Other

All Journal Article Presentation Patent

[Journal Article] Imaging Chromatin Accessibility by Assay of Transposase-Accessible Chromatin with Visualization2022
- Author(s)
  Miyanari Yusuke
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2577 Pages: 93-101
- DOI
  10.1007/978-1-0716-2724-2_7
- ISBN
  9781071627235, 9781071627242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04765
[Journal Article] Borealin-Derived Peptides as Survivin-Targeting Cancer Imaging and Therapeutic Agents2022
- Author(s)
  Nozaki Iori、Ishikawa Natsumi、Miyanari Yusuke、Ogawa Kazuma、Tagawa Ayako、Yoshida Sakura、Munekane Masayuki、Mishiro Kenji、Toriba Akira、Nakayama Morio、Fuchigami Takeshi
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 33 Issue: 11 Pages: 2149-2160
- DOI
  10.1021/acs.bioconjchem.2c00398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19452, KAKENHI-PROJECT-21H04765, KAKENHI-PUBLICLY-22H04688, KAKENHI-PROJECT-23K24276
[Journal Article] Genomic Profiling by ALaP-Seq Reveals Transcriptional Regulation by PML Bodies through DNMT3A Exclusion2020
- Author(s)
  Kurihara Misuzu、Kato Kagayaki、Sanbo Chiaki、Shigenobu Shuji、Ohkawa Yasuyuki、Fuchigami Takeshi、Miyanari Yusuke
- Journal Title
  
  Molecular Cell
  
  Volume: 78 Issue: 3 Pages: 493-505
- DOI
  10.1016/j.molcel.2020.04.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14632, KAKENHI-PROJECT-20K21398, KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-20H04846, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-18K07756, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19H03424
[Journal Article] Discovery of inner centromere protein-derived small peptides for cancer imaging and treatment targeting survivin.2020
- Author(s)
  Fuchigami T, Ishikawa N, Nozaki I, Miyanari Y, Yoshida S, Yamauchi M, Soejima A, Haratake M, Nakayama M
- Journal Title
  
  Cancer Sci
  
  Volume: 111(4) Issue: 4 Pages: 1357-1366
- DOI
  10.1111/cas.14330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07756, KAKENHI-PROJECT-18K06617
[Journal Article] Histone H1 quantity determines the efficiency of chromatin condensation in both apoptotic and live cells2019
- Author(s)
  Marie Kijima, Hiroyuki Yamagishi, Yasushi Hara, Mai Kasai, Yasunari Takami, Hiroshi Takemura, Yusuke Miyanari, Yoichi Shinkai, Ryushin Mizuta
- Journal Title
  
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
  
  Volume: 512 Issue: 2 Pages: 202-207
- DOI
  10.1016/j.bbrc.2019.03.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08891, KAKENHI-PROJECT-15H05586
[Journal Article] 核内ボディによる転写制御機構2016
- Author(s)
  栗原美寿々、宮成悠介
- Journal Title
  
  Journal of Japanese Biochemical Society
  
  Volume: 88 Pages: 521-524
- NAID
  40020948579
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05586
[Patent] 膵臓がん抗原に対するＶＨＨ抗体及び膵臓がん細胞検出方法2023
- Inventor(s)
  淵上剛志, 宮成悠介, 田川綾子, 小川数馬,他
- Industrial Property Rights Holder
  淵上剛志, 宮成悠介, 田川綾子, 小川数馬,他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-032216
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K24276
[Patent] 膵臓がん抗原に対するＶＨＨ抗体及び膵臓がん細胞検出方法2022
- Inventor(s)
  宮成悠介、淵上剛志
- Industrial Property Rights Holder
  宮成悠介、淵上剛志
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PUBLICLY-22H04688
[Presentation] Preparation and evaluation of an ADAM8-targeted 111In-labeled antibody for the detection of early pancreatic cancer2023
- Author(s)
  T. Fuchigami, T. Kosugi, Y. Miyanari, A. Tagawa, T. Adachi, K. Nishi, S. Yoshida, K. Mishiro, M. Munekane, A. Toriba, K. Ogawa
- Organizer
  The 25th International Symposium of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24276
[Presentation] 膵臓がんの初期段階での検出を目的とした ADAM8 標的とする核医学イメージングプローブの開発2022
- Author(s)
  小杉司, 淵上剛志, 宮成悠介, 田川綾子, 山口凉太, 足立智彦, 西弘大, 吉田さくら, 鳥羽陽, 小川数馬
- Organizer
  第19回次世代を担う若手のためのフィジカル・ファーマフォーラム（PPF2022）
- Data Source
  KAKENHI-PROJECT-23K24276
[Presentation] Survivin 標的Borealin 由来ペプチドを利用したがん診断治療法の開発2022
- Author(s)
  野﨑伊織, 石川夏海, 宮成悠介, 田川綾子, 吉田さくら, 鳥羽陽, 中山守雄, 小川数馬, 淵上剛志
- Organizer
  第34回バイオメディカル分析科学シンポジウム（BMAS2022）
- Data Source
  KAKENHI-PROJECT-23K24276
[Presentation] 初期膵癌の検出を目的とするADAM8 標的111In 標識イメージング薬剤の開発2022
- Author(s)
  小杉司, 淵上剛志, 宮成悠介, 田川綾子, 山口凉太, 足立智彦, 西弘大, 吉田さくら, 鳥羽陽, 小川数馬
- Organizer
  日本薬学会北陸支部第134回例会
- Data Source
  KAKENHI-PROJECT-23K24276
[Presentation] ADAM8を標的とした放射性ガリウム標識ペプチドの合成と酵素活性応答型分子プローブとしての有用性評価2021
- Author(s)
  山口涼太，小杉司，宮成悠介，田川綾子，吉田さくら，中山守雄，鳥羽陽，淵上剛志
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K07756
[Presentation] 膵臓がんの早期画像診断を目的とした 111In標識抗ADAM8抗体の開発2021
- Author(s)
  小杉司，山口涼太，棚原悠介，宮成悠介，田川綾子，足立智彦，吉田さくら，鳥羽陽，淵上剛志
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K07756
[Presentation] がん選択的な治療や診断への応用を目指した survivinを標的とする架橋ペプチドの開発2021
- Author(s)
  副島歩実，野﨑伊織，石川夏海，宮成悠介，田川綾子，吉田さくら，中山守雄，鳥羽陽，淵上剛志
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K07756
[Presentation] Genome-wide screening for regulators of chromatin accessibility2019
- Author(s)
  Yusuke Miyanari
- Organizer
  第８回植物RNA研究ネットシンポジウム、滋賀
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Development of Borealin derived peptides for survivin targeting cancer treatment2019
- Author(s)
  Iori Nozaki, Takeshi Fuchigami, Natsumi Ishikawa, Yusuke Miyanari, Motohiro Yamauchi, Riru Yamashita, Yumi Ikeda, Sakura Yoshida, and Morio Nakayama
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K07756
[Presentation] Genome-wide screening for effectors to chromatin accessiblity2019
- Author(s)
  Yusuke Miyanari
- Organizer
  10th CHROMOSOME ORCHESTRATION SYSTEM
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Genome-wide screening for regulators of chromatin accessibility2019
- Author(s)
  Yusuke Miyanari
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Survivinを標的としたBorealin由来ペプチドの合成とがん診断剤および治療薬としての基礎評価2019
- Author(s)
  野﨑伊織, 淵上剛志, 石川　夏海, 宮成　悠介，山内　基弘，池田　由美, 山下　莉瑠，吉田さくら, 中山守雄
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18K07756
[Presentation] Genome-wide screening for effectors to chromatin accessiblity2018
- Author(s)
  Yusuke Miyanari
- Organizer
  METP REUNION
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Roles of PML body in transcription2018
- Author(s)
  宮成悠介, 栗原美寿々
- Organizer
  第41会分子生物学会年会　パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-15H05586
[Presentation] Genome-wide screening for regulators of chromatin accessibility2018
- Author(s)
  Yusuke Miyanari
- Organizer
  2018 NIG international Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Genome-wide screening of key factors regulating chromatin accessiblity2018
- Author(s)
  Yusuke Miyanari
- Organizer
  9th CHROMOSOME ORCHESTRATION SYSTEM
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04722
[Presentation] Uncovering the role of PML bodies in gene expression by APEX-ChIP2017
- Author(s)
  栗原美寿々、三宝千秋、淵上剛、大川恭行、宮成悠介
- Organizer
  染色体ワークショップ
- Place of Presentation
  かずさDNA研究所（千葉県、木更津市）
- Year and Date
  2017-01-11
- Data Source
  KAKENHI-PROJECT-15H05586
[Presentation] Roles of PML body in transcription2017
- Author(s)
  宮成悠介, 栗原美寿々
- Organizer
  染色体ワークショップ
- Data Source
  KAKENHI-PROJECT-15H05586
[Presentation] Uncovering the role of PML bodies in gene expression by APEX-ChIP2016
- Author(s)
  栗原美寿々、三宝千秋、淵上剛、大川恭行、宮成悠介
- Organizer
  第39回分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H05586
[Presentation] Reprogramming and nuclear dynamics
- Author(s)
  Yusuke Miyanari
- Organizer
  4D nucleome
- Place of Presentation
  安芸グランドホテル、広島, 安芸
- Year and Date
  2014-12-19 – 2014-12-21
- Invited
- Data Source
  KAKENHI-PROJECT-26891031

1. FUCHIGAMI Takeshi (30432206)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. 吉田さくら (40736419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 中山守雄 (60164373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 柴田淳史 (30707633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山内基弘 (60437910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 安原崇哲 (90757056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小川数馬 (30347471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. MIZUTA Ryushin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 栗原美寿々

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyanari Yusuke 宮成 悠介

Research Projects

Research Products

Co-Researchers

細胞老化機構の理解と応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In cell analysis of chromatin regulating complexesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of theranostics agents combining nanobodies and PROTACs for pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dissecting a transcriptional domainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全ゲノム領域に共通した正確なDNA修復を保証するDSB修復経路選択機構の研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of nanobody molecular probes for early diagnosis of pancreatic cancers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of chromatin accessibilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

How to get transparency for generation of transparent animals.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Uncovering roles of PML bodies in transcriptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クロマチンイメージングによって解き明かす転写制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Imaging Chromatin Accessibility by Assay of Transposase-Accessible Chromatin with Visualization2022

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Borealin-Derived Peptides as Survivin-Targeting Cancer Imaging and Therapeutic Agents2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomic Profiling by ALaP-Seq Reveals Transcriptional Regulation by PML Bodies through DNMT3A Exclusion2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovery of inner centromere protein-derived small peptides for cancer imaging and treatment targeting survivin.2020

Miyanari Yusuke 宮成悠介