Moriya Hisao 守屋央朗

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MORIYA Hisao 守屋央朗

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Researcher Number	60500808
Other IDs	https://orcid.org/0000-0001-7638-3640
Affiliation (Current)	2025: 岡山大学, 環境生命自然科学学域, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 岡山大学, 環境生命自然科学学域, 教授 2020 – 2023: 岡山大学, 環境生命科学学域, 准教授 2018 – 2020: 岡山大学, 環境生命科学研究科, 准教授 2014 – 2019: 岡山大学, 異分野融合先端研究コア, 准教授 2013 – 2016: 岡山大学, その他部局等, 准教授 … More 2012: 岡山大学, 異分野融合先端コア, 准教授 2010 – 2012: 岡山大学, 異分野融合先端研究コア, 准教授 2011: 岡山大学, 異分野融先端研究コア, 助教 2009: Okayama University, 異分野融合先端研究コア, 助教 Less
Review Section/Research Field	Principal Investigator System genome science / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Biological Sciences / Basic Section 43060:System genome science-related / Science and Engineering / System genome science Except Principal Investigator Basic Section 40040:Aquatic life science-related / Medium-sized Section 29:Applied condensed matter physics and related fields / Food science / Evolutionary biology / Intelligent informatics
Keywords	Principal Investigator 酵母 / 過剰発現 / ゲノム / タンパク質毒性 / 増殖阻害 / 細胞 / タンパク質 / 揺らぎ / 制約 / ストレス環境 … More / 細胞内輸送 / プロテオーム / 微生物 / 発現制御 / 化学量不均衡 / 量感受性遺伝子 / フィードバック / 蛋白質 / 遺伝子 / 発現制約 / 毒性 / PolyX / システムバイオロジー / プロテオスタシス / 細胞毒性 / 適応進化 / 適応 / 進化 / 細胞の処理能力 / タンパク質負荷 / 処理能力 / イメージング / システム生物学 / ユビキチンープロテアソーム系 / ロバストネス / タンパク質分解 / 遺伝子発現 / 出芽酵母 / 細胞内局在 / 局在化 / プロセス負荷 / タンパク質過剰 / 生合成キャパシティー / 遺伝子量不均衡 / 量的均衡遺伝子 / タンパク質ネットワーク / 遺伝子ネットワーク / 細胞周期 … More Except Principal Investigator バイオミネラリゼーション / 分子生物学 / 細胞運動 / 細胞分化 / 固体物理学 / 応用分子細胞生物学 / 半導体デバイス工学 / 半導体物性 / 酸化鉄 / ヒザラガイ / 求電子性 / イソチオシアネート / 生化学 / 遺伝子 / 出芽酵母 / 食品 / 比較ゲノム / ゲノム重複 / 酵母 / 進化実験 / 全ゲノム重複 / パスウェイ補完 / CF帰納法 / グルコース抑制 / 帰納推論 / システム生物学 / 仮説枚挙 / 学習と知識獲得 Less

ヒザラガイの磁鉄鉱歯形成機構の解明
- Principal Investigator
  
  根本理子
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Okayama University
タンパク質の限界発現が発生させる細胞状態の解析Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Okayama University
Unraveling the comprehensive picture of expression constraints mechanisms with the new expression system gTOW2.0Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Okayama University
Cellar differentiation on the electronic semiconductor device induced by the electric stimulation
- Principal Investigator
  
  Kano Jun
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 29:Applied condensed matter physics and related fields
- Research Institution
  Okayama University
連続するアミノ酸（PolyX）が生み出す細胞毒性のメカニズムPrincipal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Okayama University
ヒザラガイの磁鉄鉱歯特異的な歯舌マトリックスタンパク質の機能解明
- Principal Investigator
  
  根本理子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Okayama University
発現量揺らぎ－適応系により探索する発現変動の適応－進化への影響Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Mechanism of growth inhibition by overexpression explored from the expression level of the limiting mutant proteinPrincipal Investigator
- Principal Investigator
  
  Moriya Hisao
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Okayama University
Cell processing capacity explored by expression limits of proteinsPrincipal Investigator
- Principal Investigator
  
  Moriya Hisao
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Okayama University
発現量揺らぎー適応系により探るプロテオームの制約条件とその適応ー進化への影響Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Okayama University
Identification and characterization of phytochemical-targeted genes using a genome wide yeast screening system
- Principal Investigator
  
  Nakamura Yoshimasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Okayama University
Systematic analysis of proteins that cause overload of transport resources due to overexpressionPrincipal Investigator
- Principal Investigator
  
  Moriya Hisao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Okayama University
Analysis of mechanisms avoiding stoichometry imbalance(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Moriya Hisao
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  System genome science
- Research Institution
  Okayama University
Analysis of mechanisms to avoid stoichiometry imbalancePrincipal Investigator
- Principal Investigator
  
  Moriya Hisao
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Okayama University
Experimental verification of gene loss patterns in yeast genome after whole genome duplication
- Principal Investigator
  
  Makino Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Evolutionary biology
- Research Institution
  Tohoku University
酵母の生合成キャパシティーの拡大Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Okayama University
Analysis of the mechanisms of process burdens in yeastPrincipal Investigator
- Principal Investigator
  
  HISAO Moriya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  System genome science
- Research Institution
  Okayama University
情報場への摂動を緩衝するメカニズムの解明Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Analysis of the network constructed by dosage balanced genes in yeastPrincipal Investigator
- Principal Investigator
  
  MORIYA Hisao
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Okayama University
Hypothesis Enumeration for Knowledge Discovery in Systems Biology
- Principal Investigator
  
  YAMAMOTO Yoshitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Intelligent informatics
- Research Institution
  University of Yamanashi
遺伝情報場へのフィードバックの同定Principal Investigator
- Principal Investigator
  
  守屋央朗
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University

[Journal Article] Protein sorting upon exit from the endoplasmic reticulum dominates Golgi biogenesis in budding yeast2024
- Author(s)
  Sasaki Saku、Schlarmann Philipp、Hanaoka Kazuki、Nishii Hinako、Moriya Hisao、Mu?iz Manuel、Funato Kouichi
- Journal Title
  
  FEBS Letters
  
  Volume: 598 Issue: 5 Pages: 548-555
- DOI
  10.1002/1873-3468.14830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19294, KAKENHI-PROJECT-21K19088, KAKENHI-PROJECT-20H03242, KAKENHI-PROJECT-23K26868
[Journal Article] Overexpression profiling reveals cellular requirements in the context of genetic backgrounds and environments2023
- Author(s)
  Saeki Nozomu、Yamamoto Chie、Eguchi Yuichi、Sekito Takayuki、Shigenobu Shuji、Yoshimura Mami、Yashiroda Yoko、Boone Charles、Moriya Hisao
- Journal Title
  
  PLOS Genetics
  
  Volume: 19 Issue: 4 Pages: e1010732-e1010732
- DOI
  10.1371/journal.pgen.1010732
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21J12451, KAKENHI-PROJECT-22K19294, KAKENHI-PROJECT-21K05507, KAKENHI-PLANNED-23H04882, KAKENHI-PROJECT-20H03242, KAKENHI-PROJECT-23K23491
[Journal Article] Demonstration of iodide-dependent UVA-triggered growth inhibition in Saccharomyces cerevisiae cells and identification of its suppressive molecules2023
- Author(s)
  Ono Ryota、Saeki Nozomu、Kojima Keiichi、Moriya Hisao、Sudo Yuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 677 Pages: 1-5
- DOI
  10.1016/j.bbrc.2023.07.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19294, KAKENHI-PROJECT-20H03242, KAKENHI-PROJECT-21H02446, KAKENHI-PROJECT-23K27142
[Journal Article] Massive expression of cysteine-containing proteins causes abnormal elongation of yeast cells by perturbing the proteasome2022
- Author(s)
  Namba Shotaro、Kato Hisaaki、Shigenobu Shuji、Makino Takashi、Moriya Hisao
- Journal Title
  
  G3 Genes|Genomes|Genetics
  
  Volume: - Issue: 6
- DOI
  10.1093/g3journal/jkac106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04870, KAKENHI-PROJECT-22K19294, KAKENHI-PROJECT-19K22294, KAKENHI-PROJECT-20H03242
[Journal Article] Identification of uncharacterized proteins potentially localized to mitochondria (UPMs) in <scp> <i>Saccharomyces cerevisiae</i> </scp> using a fluorescent protein unstable in the cytoplasm2021
- Author(s)
  Horiuchi Satoshi、Namba Shotaro、Saeki Nozomu、Satoh Ayano、Moriya Hisao
- Journal Title
  
  Yeast
  
  Volume: 39 Issue: 5 Pages: 303-311
- DOI
  10.1002/yea.3685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03242, KAKENHI-PUBLICLY-20H04870
[Journal Article] Genetic profiling of protein burden and nuclear export overload.2020
- Author(s)
  Kintaka R, Makanae K, Namba S, Kato H, Kito K, Ohnuki S, Ohya Y, Andrews BJ, Boone C, Moriya H.
- Journal Title
  
  Elife
  
  Volume: 9
- DOI
  10.7554/elife.54080
- NAID
  120006941058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06411, KAKENHI-PUBLICLY-20H04870, KAKENHI-PROJECT-18K06228, KAKENHI-PROJECT-18K19300, KAKENHI-PROJECT-19H03205
[Journal Article] Development of an experimental method of systematically estimating protein expression limits in HEK293 cells2020
- Author(s)
  Mori Yoshihiro、Yoshida Yuki、Satoh Ayano、Moriya Hisao
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-61646-3
- NAID
  120006883502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19300, KAKENHI-PUBLICLY-18H04824, KAKENHI-PROJECT-17H03618
[Journal Article] N-terminal deletion of Swi3 created by the deletion of a dubious ORF YJL175W mitigates protein burden effect in S. cerevisiae2020
- Author(s)
  Saeki Nozomu、Eguchi Yuichi、Kintaka Reiko、Makanae Koji、Shichino Yuichi、Iwasaki Shintaro、Kanno Manabu、Kimura Nobutada、Moriya Hisao
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 9500-9500
- DOI
  10.1038/s41598-020-66307-z
- NAID
  120006883501
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04870, KAKENHI-PROJECT-18K19300, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04998, KAKENHI-PROJECT-19K22406, KAKENHI-PLANNED-20H05784
[Journal Article] The expression level and cytotoxicity of green fluorescent protein are modulated by an additional N-terminal sequence2020
- Author(s)
  Moriya Hisao、Graduate School of Environmental and Life Sciences, Research Core for Interdisciplinary Sciences, Okayama University
- Journal Title
  
  AIMS Biophysics
  
  Volume: 7 Issue: 2 Pages: 121-132
- DOI
  10.3934/biophy.2020010
- NAID
  120006860108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19300, KAKENHI-PUBLICLY-18H04824, KAKENHI-PROJECT-17H03618
[Journal Article] Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes2020
- Author(s)
  Ishikawa Koji、Ishihara Akari、Moriya Hisao
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 10 Pages: e1009091-e1009091
- DOI
  10.1371/journal.pgen.1009091
- NAID
  120006937515
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04870, KAKENHI-PROJECT-18K19300
[Journal Article] Comparative gene analysis focused on silica cell wall formation: Identification of diatom-specific SET domain protein methyltransferases2020
- Author(s)
  Nemoto, M., Iwaki, S., Moriya, H., Monden, Y., Tamura, T., Inagaki, K., Mayama, S. and Obuse K.
- Journal Title
  
  Marine Biotechnology
  
  Volume: － Issue: 4 Pages: 551-563
- DOI
  10.1007/s10126-020-09976-1
- NAID
  120007045009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05818, KAKENHI-PUBLICLY-20H04870, KAKENHI-PROJECT-18K19300
[Journal Article] Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis122019
- Author(s)
  Abe-Kanoh Naomi、Kunisue Narumi、Myojin Takumi、Chino Ayako、Munemasa Shintaro、Murata Yoshiyuki、Satoh Ayano、Moriya Hisao、Nakamura Yoshimasa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 8866-8866
- DOI
  10.1038/s41598-019-45248-2
- NAID
  120006648600
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19300, KAKENHI-PROJECT-19K15789, KAKENHI-PUBLICLY-18H04824, KAKENHI-PROJECT-17H03618, KAKENHI-PROJECT-17H03818
[Journal Article] Estimating the Protein Burden Limit of Yeast Cells by Measuring Expression Limits of Glycolytic Proteins.2018
- Author(s)
  Eguchi, Y., Makanae, K., Hasunuma, T., Ishibashi, Y., Kito, K., Moriya, H.
- Journal Title
  
  Elife
  
  Volume: 7
- DOI
  10.7554/elife.34595
- NAID
  120006501235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06228, KAKENHI-PROJECT-18K19300, KAKENHI-PROJECT-17H03618, KAKENHI-PROJECT-15KK0258, KAKENHI-PUBLICLY-18H04824
[Journal Article] Genetic Analysis of Signal Generation by the Rgt2 Glucose Sensor of Saccharomyces cerevisiae2018
- Author(s)
  Scharff-Poulsen Peter、Moriya Hisao、Johnston Mark
- Journal Title
  
  G3
  
  Volume: 8 Issue: 8 Pages: 2685-2696
- DOI
  10.1534/g3.118.200338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19300, KAKENHI-PROJECT-17H03618, KAKENHI-PROJECT-15KK0258, KAKENHI-PUBLICLY-18H04824
[Journal Article] Assessing phagotrophy in the mixotrophic ciliate Paramecium bursaria using GFP-expressing yeast cells2017
- Author(s)
  Miura T, Moriya H, Iwai S.
- Journal Title
  
  FEMS Microbiol Lett.
  
  Volume: 364 Issue: 12 Pages: 12-12
- DOI
  10.1093/femsle/fnx117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KK0258
[Journal Article] Post-translational dosage compensation buffers genetic perturbations to stoichiometry of protein complexes2017
- Author(s)
  Koji Ishikawa, Koji Makanae, Shintaro Iwasaki, Nicholas T. Ingolia, Hisao Moriya
- Journal Title
  
  PLoS Genetics
  
  Volume: 13(1) Issue: 1 Pages: e1006554-e1006554
- DOI
  10.1371/journal.pgen.1006554
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J00852, KAKENHI-PROJECT-26290069, KAKENHI-PROJECT-15KK0258
[Journal Article] Cellular growth defects triggered by an overload of protein localization processes2016
- Author(s)
  Kintaka R, Makanae K, Moriya H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 31774-31774
- DOI
  10.1038/srep31774
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26290069, KAKENHI-PROJECT-15KK0258
[Journal Article] Quantitative nature of overexpression experiments.2016
- Author(s)
  Moriya H
- Journal Title
  
  Mol Biol Cell
  
  Volume: 26 Issue: 22 Pages: 3932-3939
- DOI
  10.1091/mbc.e15-07-0512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290069
[Journal Article] Small Toxic Protein Encoded on Chromosome VII of Saccharomyces cerevisiae2015
- Author(s)
  Makanae K, Kintaka R, Ishikawa K, Moriya H
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120678-e0120678
- DOI
  10.1371/journal.pone.0120678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25640115, KAKENHI-PROJECT-26290069
[Journal Article] Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes2015
- Author(s)
  Bonney ME, Moriya H, Amon A
- Journal Title
  
  Genes Dev.
  
  Volume: 29 Issue: 9 Pages: 898-903
- DOI
  10.1101/gad.261743.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25640115, KAKENHI-PROJECT-26290069
[Journal Article] Evaluation of the lower protein limit in the budding yeast Saccharomyces cerevisiae using TIPI-gTOW2014
- Author(s)
  Sasabe M, Shintani S, Kintaka R, Kaizu K, Makanae K, Moriya H
- Journal Title
  
  BMC Syst Biol
  
  Volume: 8(1) Issue: 1 Pages: 2-2
- DOI
  10.1186/1752-0509-8-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310140, KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25640115
[Journal Article] Relationships between Cell Cycle Regulator Gene Copy Numbers and Protein Expression Levels in Schizosaccharomyces pombe2013
- Author(s)
  Chino A, Makanae K, Moriya H.
- Journal Title
  
  PLoS One
  
  Volume: 8(9) Issue: 9 Pages: e73319-e73319
- DOI
  10.1371/journal.pone.0073319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310140, KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25640115
[Journal Article] Spiro-carbon formation by different chemistry involving pathway crosstalk.2013
- Author(s)
  石川格靖, 他8名
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 9 Issue: 12 Pages: 818-825
- DOI
  10.1038/nchembio.1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10688, KAKENHI-PROJECT-23310140, KAKENHI-PROJECT-23406031, KAKENHI-PUBLICLY-25108717, KAKENHI-PROJECT-25242067, KAKENHI-PROJECT-25640115
[Journal Article] Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method2013
- Author(s)
  Koji Makanae, Reiko Kintaka, Takashi Makino, Hiroaki Kitano and Hisao Moriya
- Journal Title
  
  Genome Research
  
  Volume: 23 Issue: 2 Pages: 300-311
- DOI
  10.1101/gr.146662.112
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PROJECT-22405008, KAKENHI-PROJECT-23310140, KAKENHI-PLANNED-22136003, KAKENHI-PUBLICLY-23114715
[Journal Article] Parallel Real-Time PCR on a Chip for Genetic Tug-of-War (gTOW) Method2013
- Author(s)
  Naito T, Yatsuhashi A, Kaji N, Ando T, Sato K, Moriya H, Kitano H, Yasui T, Tokeshi M, Baba Y
- Journal Title
  
  Anal Sci
  
  Volume: 29(3) Pages: 367-71
- NAID
  10031165324
- URL
  https://www.jstage.jst.go.jp/article/analsci/29/3/29_367/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310140
[Journal Article] A Genome-Wide Activity Assessment of Terminator Regions in Saccharomyces cerevisiae Provides a "Terminatome″Toolbox2013
- Author(s)
  Yamanishi M, Ito Y, Kintaka R, Imamura C, Katahira S, Ikeuchi A, Moriya H, Matsuyama T
- Journal Title
  
  ACS Synth Biol
  
  Volume: 2 Issue: 6 Pages: 337-347
- DOI
  10.1021/sb300116y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310140
[Journal Article] Robustness analysis of cellular systems using the genetic tug-of-war method2012
- Author(s)
  Moriya H, Makanae K, Watanabe K, Chino A, Shimizu-Yoshida Y
- Journal Title
  
  Mol Biosyst
  
  Volume: 8(10) Issue: 10 Pages: 2513-22
- DOI
  10.1039/c2mb25100k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310140, KAKENHI-PUBLICLY-23114715
[Journal Article] Establishing a New Methodology for Genome Mining and Biosynthesis of Polyketides and Peptides through Yeast Molecular Genetics2012
- Author(s)
  石内勘一郎、佐藤道大, 他9名
- Journal Title
  
  Chembiochem
  
  Volume: 13 Issue: 6 Pages: 846-854
- DOI
  10.1002/cbic.201100798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01668, KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23310140, KAKENHI-PROJECT-23406031, KAKENHI-PROJECT-23880025
[Journal Article] Overexpression limits of fission yeast cell-cycle regulators in vivo and in silico2011
- Author(s)
  Moriya H, Chino A, Kapuy O, Csikasz-Nagy A, Novak B
- Journal Title
  
  Molecular Systems Biology
  
  Volume: 7 Issue: 1 Pages: 556-556
- DOI
  10.1038/msb.2011.91
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23114715, KAKENHI-PROJECT-23310140
[Journal Article] Plasmid construction using recombination activity in the fission yeast Schizosaccharomyces pombe.2010
- Author(s)
  Ayako Chino, Kenji Watanabe, Hisao Moriya
- Journal Title
  
  PLoS One 5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21114515
[Journal Article] Fragilliles caused by dosage imbalance in regulation of the budding yeast cell cycle2010
- Author(s)
  K.Kaizu, H.Moriya, H.Kitano
- Journal Title
  
  PLoS genotic
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21114515
[Journal Article] A comprehensive molecular interaction map of the budding yeast cell cycle2010
- Author(s)
  K.Kaizu, S.Ghosh, Y.Mutsuoka, H.Moriya, Y.Shimizu-Yoshida, H.Kitano
- Journal Title
  
  Molecular Systems Biology
  
  Volume: 6 Pages: 415-415
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21114515
[Patent] 細胞小器官局在性融合タンパク質2016
- Inventor(s)
  守屋央朗
- Industrial Property Rights Holder
  守屋央朗
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 出芽酵母のデノボ遺伝子の機能解析2020
- Author(s)
  守屋央朗
- Organizer
  第43回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] 多コピー化が高塩ストレス下で適応的にはたらく遺伝子の体系的探索2020
- Author(s)
  佐伯望、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] 3XGFPの過剰発現が引き起こす増殖阻害現象2020
- Author(s)
  難波匠太郎、金高令子、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] 出芽酵母のデノボ遺伝子の機能解析2020
- Author(s)
  守屋央朗
- Organizer
  第43回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 過剰発現が適応的に働く遺伝子の体系的同定2020
- Author(s)
  守屋央朗、佐伯
- Organizer
  日本進化学会第22回オンライン大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 過剰発現が適応的に働く遺伝子の体系的同定2020
- Author(s)
  守屋央朗、佐伯望
- Organizer
  日本進化学会第22回オンライン大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] システインを含むタンパク質の過剰発現は出芽酵母の形態異常をもたらす2020
- Author(s)
  加藤寿明、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] 高塩ストレス下で多コピー化が適応的に機能する出芽酵母遺伝子の体系的探索2020
- Author(s)
  佐伯望、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04870
[Presentation] 3XGFPの過剰発現が引き起こす増殖阻害現象2020
- Author(s)
  難波匠太郎、金高令子、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 高塩ストレス下で多コピー化が適応的に機能する出芽酵母遺伝子の体系的探索2020
- Author(s)
  佐伯望、守屋央朗
- Organizer
  第43回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 多コピー化が高塩ストレス下で適応的にはたらく遺伝子の体系的探索2020
- Author(s)
  佐伯望、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] システインを含むタンパク質の過剰発現は出芽酵母の形態異常をもたらす2020
- Author(s)
  加藤寿明、守屋央朗
- Organizer
  酵母遺伝学フォーラム第53回研究報告会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 過剰発現が適応的に働く遺伝子の体系的同定2019
- Author(s)
  守屋央朗
- Organizer
  日本進化学会第21回大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] Systematic Identification of Genes Whose Overexpression Works Adaptively Using the ADOPT System2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  The 20th International Conference on Systems Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] 過剰発現が適応的に働く遺伝子の体系的同定2019
- Author(s)
  守屋央朗
- Organizer
  日本進化学会第21回大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Systematic Identification of Genes whose Overexpression Positively Affect Fitness in Various Environments2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] Systematic Identification of Genes whose Overexpression Positively Affect Fitness in Various Environments2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] Systematic Identification of Genes Whose Overexpression Works Adaptively Using the ADOPT System2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  The 20th International Conference on Systems Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] Systematic Identification of Genes whose Overexpression Positively Affect Fitness in Various Environments2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Genetic profiling of protein burden and nuclear export overload2019
- Author(s)
  金高令子、Charlie Boone、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] 過剰発現が適応的に働く遺伝子の体系的同定2019
- Author(s)
  守屋央朗
- Organizer
  日本進化学会第21回大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] Genetic profiling of protein burden and nuclear export overload2019
- Author(s)
  金高令子、Charlie Boone、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] Genetic profiling of protein burden and nuclear export overload2019
- Author(s)
  金高令子、Charlie Boone、守屋央朗
- Organizer
  ICYGMB 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 過剰発現実験により探るプロテオームの拘束条件2019
- Author(s)
  守屋央朗
- Organizer
  日本遺伝学会第91回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Systematic Identification of Genes Whose Overexpression Works Adaptively Using the ADOPT System2019
- Author(s)
  佐伯望、守屋央朗
- Organizer
  The 20th International Conference on Systems Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] 過剰発現実験により探るプロテオームの拘束条件2019
- Author(s)
  守屋央朗
- Organizer
  日本遺伝学会第91回大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] 過剰発現実験により探るプロテオームの拘束条件2019
- Author(s)
  守屋央朗
- Organizer
  日本遺伝学会第91回大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] タンパク質の発現限界を測る遺伝学的手法TOW-Fu2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Defining harmful yeast oroteins by mesuring overexpression limits2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  2018 Yeast Genetics Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] 過剰発現の限界から探る細胞の処理能力2018
- Author(s)
  守屋央朗、江口優一、蒔苗浩司、加藤有香
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 多コピー化が増殖に有利に働く酵母遺伝子のハイスループットスクリーニング2018
- Author(s)
  佐伯望、江口優一、堀内智司、Herbst Konrad、Kirrmaier Daniel、Knop Michael 、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Defining harmful yeast oroteins by mesuring overexpression limits2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  2018 Yeast Genetics Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] 哺乳類細胞においてタンパク質発現量の限界を測定する実験系の確立と改善2018
- Author(s)
  森吉弘、佐藤あやの、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] 過剰発現の限界から探る細胞の処理能力2018
- Author(s)
  守屋央朗、江口優一、蒔苗浩司、加藤有香
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] タンパク質の限界発現量から探る細胞の処理能力2018
- Author(s)
  守屋央朗、加藤有香
- Organizer
  酵母遺伝学フォーラム第51回研究報告会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] 多コピー化が増殖に有利に働く酵母遺伝子のハイスループットスクリーニング2018
- Author(s)
  佐伯望、江口優一、堀内智司、Herbst Konrad、Kirrmaier Daniel、Knop Michael 、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Defining harmful yeast oroteins by mesuring overexpression limits2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  2018 Yeast Genetics Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 過剰に対する細胞システムのロバストネスと脆弱性2018
- Author(s)
  守屋央朗
- Organizer
  数理シグナル学術領域の新展開（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 多コピー化が増殖に有利に働く酵母遺伝子のハイスループットスクリーニング2018
- Author(s)
  佐伯望、江口優一、堀内智司、Herbst Konrad、Kirrmaier Daniel、Knop Michael 、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] タンパク質の発現限界を測る遺伝学的手法TOW-Fu2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 多コピー化が増殖に有利に働く酵母遺伝子のハイスループットスクリーニング2018
- Author(s)
  佐伯望、江口優一、堀内智司、Herbst Konrad、Kirrmaier Daniel、Knop Michael 、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] 過剰発現の限界から探る細胞の処理能力2018
- Author(s)
  守屋央朗、江口優一、蒔苗浩司、加藤有香
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04824
[Presentation] Defining harmful yeast oroteins by mesuring overexpression limits2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  2018 Yeast Genetics Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] タンパク質の限界発現量から探る細胞の処理能力2018
- Author(s)
  守屋央朗、加藤有香
- Organizer
  酵母遺伝学フォーラム第51回研究報告会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] タンパク質の限界発現量から探る細胞の処理能力2018
- Author(s)
  守屋央朗、加藤有香
- Organizer
  酵母遺伝学フォーラム第51回研究報告会
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] タンパク質の発現限界を測る遺伝学的手法TOW-Fu2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03618
[Presentation] 過剰発現の限界から探る細胞の処理能力2018
- Author(s)
  守屋央朗、江口優一、蒔苗浩司、加藤有香
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] タンパク質の発現限界を測る遺伝学的手法TOW-Fu2018
- Author(s)
  江口優一、守屋央朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19300
[Presentation] cODCデグロンを利用した新技術の開発2017
- Author(s)
  堀内智司、守屋央朗
- Organizer
  第35回YEAST WORKSHOP
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Consequences of Protein Overexpression: Approaches by the Genetic Tug-of-war Method2017
- Author(s)
  Hisao Moriya
- Organizer
  CIFAR Genetic Networks Program Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 哺乳類細胞においてタンパク質発現量の限界を測定する実験系の確立および解析2017
- Author(s)
  森吉弘、吉田由紀、北野弘明、佐藤あやの、守屋央朗
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] タンパク質発現量の限界を規定する要因の解析2017
- Author(s)
  江口優一、蒔苗浩司、堀良美、蓮沼誠久、守屋央朗
- Organizer
  第69会日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 哺乳類細胞においてタンパク質発現量の限界を測定する実験系の確立2017
- Author(s)
  森吉弘、吉田由紀、北野弘明、佐藤あやの、守屋央朗
- Organizer
  第69回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Tpkの過剰が引き起こす増殖阻害に対する、キナーゼ活性の寄与度の検証2017
- Author(s)
  石原明莉、守屋央朗
- Organizer
  第35回YEAST WORKSHOP
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 摂動実験により探るプロテオームの拘束条件2017
- Author(s)
  守屋央朗
- Organizer
  日本プロテオーム学会2017年大会
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] タンパク質の発現限界を測る遺伝学的手法の開発2017
- Author(s)
  江口優一、守屋央朗
- Organizer
  第4回摂動生物学研究会
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Expression limits of glycolytic enzymes in yeast2016
- Author(s)
  Yuichi Eguchi, Koji Makanae, Yoshimi Hori, Tomohisa Hasunuma, Hisao Moriya
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Perturbed stoichiometry of complex subunits is circumvented by protein-level dosage compensation2016
- Author(s)
  Koji Ishikawa, Koji Makanae, Hisao Moriya
- Organizer
  The 9th Asian Young Res. Conf. on Comput. and Omics Biol.
- Place of Presentation
  シンガポール
- Year and Date
  2016-01-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Consequences of protein overexpression2016
- Author(s)
  Hisao Moriya, Reiko Kintaka, Charles Boone, Koji Ishikawa, Yuichi Eguchi
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Overloads of protein localization process cause cellular growth defects2016
- Author(s)
  Reiko Kintaka, Koji Makanae, Hisao Moriya
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Consequences of protein overexpression2016
- Author(s)
  Hisao Moriya, Reiko Kintaka, Charles Boone, Koji Ishikawa, Yuichi Eguchi
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Consequences of protein overexpression2016
- Author(s)
  Hisao Moriya
- Organizer
  The 26th Hot Spring Harbor International Symposium
- Place of Presentation
  福岡県福岡市
- Year and Date
  2016-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Overloads of protein localization process cause cellular growth defects2016
- Author(s)
  Reiko Kintaka, Koji Makanae, Hisao Moriya
- Organizer
  14th International Congress on Yeasts
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] Consequences of protein overexpression2016
- Author(s)
  Hisao Moriya
- Organizer
  The 26th Hot Spring Harbor International Symposium
- Place of Presentation
  福岡県福岡市
- Year and Date
  2016-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0258
[Presentation] 細胞内でタンパク質発現量の限界を決める要因はなにか？2015
- Author(s)
  守屋央朗
- Organizer
  第5回合成生物工学シンポジウム
- Place of Presentation
  神戸市
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 細胞の持つタンパク質発現のキャパシティを測る2015
- Author(s)
  守屋央朗
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県・岡山市
- Year and Date
  2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] 細胞の持つタンパク質発現のキャパシティーを測る2015
- Author(s)
  守屋央朗
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県・岡山市
- Year and Date
  2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] Robust gene expression under genetic perturbation: New mechanism maintaining stoichiometry of protein complex2015
- Author(s)
  Koji Ishikawa, Koji Makanae, Hisao Moriya
- Organizer
  The 16th International Conference on Systems Biology
- Place of Presentation
  シンガポール
- Year and Date
  2015-11-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 遺伝子発現の摂動に対してタンパク質発現量を調整する新たな分子機構の解析2015
- Author(s)
  石川浩史、蒔苗浩司、守屋央朗
- Organizer
  酵母遺伝学フォーラム第48回報告会
- Place of Presentation
  東広島市
- Year and Date
  2015-09-01
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] タンパク質の過剰発現が及ぼす影響とそれに対する細胞のストラテジー2015
- Author(s)
  守屋央朗、石川浩史、江口優一、金高令子、蒔苗浩司
- Organizer
  BMB2015
- Place of Presentation
  神戸市
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 遺伝子発現系への摂動をタンパク質レベルで緩衝する新たな分子機構の解析2015
- Author(s)
  石川浩史、蒔苗浩司、守屋央朗
- Organizer
  BMB2015
- Place of Presentation
  神戸市
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 細胞の持つタンパク質発現のキャパシティを測る2015
- Author(s)
  守屋央朗
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山県・岡山市
- Year and Date
  2015-03-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] 細胞システムのロバストネスを測る。2014
- Author(s)
  守屋央朗
- Organizer
  制御・情報理論による生物システムのロバストネス解析と設計」第1回講演会
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-09-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] タンパク質の発現量の限界を測る。2014
- Author(s)
  守屋央朗
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  茨城県・つくば市
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] タンパク質発現量の限界を決める要素は何か？2014
- Author(s)
  守屋央朗
- Organizer
  「細胞を創る」研究会7.0
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 細胞システムのロバストネスを測る2014
- Author(s)
  守屋央朗
- Organizer
  制御・情報理論による生物システムのロバストネス解析と設計」第1回講演会
- Place of Presentation
  東京都文京区
- Year and Date
  2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質発現量の限界を決める要素は何か？2014
- Author(s)
  守屋央朗
- Organizer
  細胞を創る研究会7.0
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質の発現量の限界を測る。2014
- Author(s)
  守屋央朗
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  茨城県・つくば市
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質発現量の限界を決める要素は何か？2014
- Author(s)
  守屋央朗
- Organizer
  細胞を創る研究会7.0
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] Evaluation of cytotoxicity caused by overproduction of localized signal attached GFPs2014
- Author(s)
  Reiko Kintaka, Koji Makanae, Hisao Moriya
- Organizer
  Yeast genetics meeting 2014
- Place of Presentation
  Seattle, USA
- Year and Date
  2014-07-29
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質の発現量の限界を測る。2014
- Author(s)
  守屋央朗
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  茨城県・つくば市
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 細胞システムのロバストネスを測る2014
- Author(s)
  守屋央朗
- Organizer
  「制御・情報理論による生物システムのロバストネス解析と設計」第1回公演
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 細胞システムのロバストネスを測る。2014
- Author(s)
  守屋央朗
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府・京都市
- Year and Date
  2014-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] 細胞システムのロバストネスを測る2014
- Author(s)
  守屋央朗
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府・京都市
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-26290069
[Presentation] 酵母だから測れる（？）、過剰発現のコピー数限界2013
- Author(s)
  守屋央朗
- Organizer
  日本分子生物学会第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] 酵母の量感受性遺伝子の多コピーサプレッサーによる解析2013
- Author(s)
  金高令子、守屋央朗
- Organizer
  日本分子生物学会　第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 酵母だから測れる（？）、過剰発現のコピー数限界2013
- Author(s)
  守屋央朗
- Organizer
  日本分子生物学会　第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 酵母の量感受性遺伝子の多コピーサプレッサーによる解析2013
- Author(s)
  金高令子、守屋央朗
- Organizer
  日本分子生物学会第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] TIPI-gTOW 法によるタンパク質発現の下限限定の試み2013
- Author(s)
  雀部正毅, 進谷紗弓, 守屋央朗
- Organizer
  酵母遺伝学フォーラム第46回研究報告会
- Place of Presentation
  仙台市青葉区
- Year and Date
  2013-09-08
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 酵母の量感受性遺伝子の多コピーサプレッサーによる解析2013
- Author(s)
  金高令子，守屋央朗
- Organizer
  日本分子生物学会　第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] 出芽酵母におけるmisfoldedGFP の過剰発現による細胞毒性の発揮メカニズムの解析2013
- Author(s)
  蒔苗浩志, 守屋央朗
- Organizer
  酵母遺伝学フォーラム第46回研究報告会
- Place of Presentation
  仙台市青葉区
- Year and Date
  2013-09-08
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 酵母だから測れる（？）、過剰発現のコピー数限界2013
- Author(s)
  守屋央朗
- Organizer
  日本分子生物学会　第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] 酵母だから測れる(?),過剰発現のコピー数限界2013
- Author(s)
  守屋央朗
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 出芽酵母がもつすべての遺伝子の限界発現量を測る2012
- Author(s)
  守屋央朗
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] タンパク質の過剰に対して,細胞の各プロセスは異なった頑健性を持っている2012
- Author(s)
  守屋央朗, 蒔苗浩司
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  京都府宇治市
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] ミトコンドリア関連の量感受性遺伝子(DSG)とPPH3 の遺伝的相互作用2012
- Author(s)
  金高令子, 蒔苗浩司, 守屋央朗
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  京都府宇治市
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] ミトコンドリア関連の量感受性遺伝子(DSG)とPPH3 の遺伝的相互作用2012
- Author(s)
  金高令子, 蒔苗浩司, 守屋央朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 分裂酵母の細胞周期に存在するフィードバックの解明2012
- Author(s)
  茅野文子, 守屋央朗
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  京都府宇治市
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Development of a method for measuring the lower limit of gene expression2012
- Author(s)
  Masataka Sasabe, Sayumi Shintani, Koji Makanae, Hisao Moriya
- Organizer
  2012 Yeast Genetics and Molecular Biology Meeting
- Place of Presentation
  アメリカ,ニュージャージー州)
- Year and Date
  2012-08-01
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 分裂酵母の細胞周期に存在するフィードバックの解明2012
- Author(s)
  守屋央朗
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  京都府宇治市
- Data Source
  KAKENHI-PUBLICLY-23114715
[Presentation] 出芽酵母がもつすべての遺伝子の限界発現量を測る2012
- Author(s)
  蒔苗浩司, 金高令子, 牧野能士, 守屋央朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] タンパク質の過剰発現が引き起こす細胞毒性の定量2012
- Author(s)
  蒔苗浩司, 守屋央朗
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Identification of genes in balance with dosage sensitive genes2012
- Author(s)
  Reiko Kintaka, Koji Makanae, Hisao Moriya
- Organizer
  2012 Yeast Genetics and Molecular Biology Meeting
- Place of Presentation
  アメリカ,ニュージャージー州
- Year and Date
  2012-08-01
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Dosage sensitive gene と均衡関係にある遺伝子の同定2011
- Author(s)
  金高令子, 守屋央朗
- Organizer
  イーストワークショップ
- Place of Presentation
  香川県さぬき市
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 遺伝子発現の下限測定法の開発2011
- Author(s)
  進谷紗弓 ,蒔苗浩司, 守屋央朗
- Organizer
  イーストワークショップ
- Place of Presentation
  香川県さぬき市
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 分裂酵母細胞周期のロバストネスを生み出す機構の解析2011
- Author(s)
  茅野文子、守屋央朗
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-23114715
[Presentation] 出芽酵母の遺伝子量感受性遺伝子2011
- Author(s)
  守屋央朗
- Organizer
  第7回真菌分子細胞研究会
- Place of Presentation
  香川県さぬき市(招待講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Dosage sensitive geneと均衡関係にある遺伝子の同定2011
- Author(s)
  金高令子、守屋央朗
- Organizer
  イーストワークショップ
- Place of Presentation
  香川県さぬき市
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 分裂酵母細胞周期の遺伝子発現システムに存在する緩衝機構の解明2011
- Author(s)
  茅野文子、守屋央朗
- Organizer
  酵母遺伝学フォーラム第44回研究報告会
- Place of Presentation
  福岡県博多市
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PUBLICLY-23114715
[Presentation] 酵母細胞システムのロバストネス解析2011
- Author(s)
  守屋央朗
- Organizer
  第49会日本生物物理学会年会
- Place of Presentation
  兵庫県姫路市
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 酵母細胞システムのロバストネス解析2011
- Author(s)
  守屋央朗
- Organizer
  生物物理学会第49回年会
- Place of Presentation
  姫路市書写
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Robustness analysis of yeast cell cycle in silico and in vivo2011
- Author(s)
  Hisao Moriya
- Organizer
  International Symposium on Symbolic Systems Biology 2011
- Place of Presentation
  神奈川県三浦郡(招待講演)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23114715
[Presentation] The genome-wide analysis of limit of gene-overexpression in S cerevisiae2011
- Author(s)
  Hisao Moriya
- Organizer
  International Symposium on the Physicochemical Field for Genetics Activities
- Place of Presentation
  Hyogo, Japan
- Year and Date
  2011-01-24
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] Identification of dosage sensitive genes on the budding yeast genome2011
- Author(s)
  守屋央朗
- Organizer
  Young Researchers Conference on Evolutionary Genomics
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Dosage sensitive geneのパートナー分子の同定2011
- Author(s)
  金高令子、守屋央朗
- Organizer
  酵母遺伝学フォーラム第44回年会
- Place of Presentation
  福岡県博多市
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] Dosage sensitive geneと均衡関係にある遺伝子の同定2011
- Author(s)
  金高令子、守屋央朗
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23310140
[Presentation] 細胞システムのロバストネスを測る～酵母をモデル系として～2010
- Author(s)
  守屋央朗
- Organizer
  明治大学グローバルCOE研究会
- Place of Presentation
  神奈川県川崎市
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] In vivo robustness analysis of the yest cell cycle2010
- Author(s)
  守屋央朗
- Organizer
  The 13th US-Japan Cellular and Gene Therapy Conference on Systems Biology in Cell Cycle Regultion
- Place of Presentation
  Besesda/USA
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] 分裂酵母で相同組換えを利用した遺伝子クローニング(GCR)は実用に耐えるか?2009
- Author(s)
  茅野文子・守屋央朗
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] IN VIVO ROBUSTNESS ANALYSIS OF THE FISSION YEAST CELL CYCLE SYSTEM2009
- Author(s)
  Ayako Chino, Hisao Moriya
- Organizer
  The 5th International Fission Yeast Meeting
- Place of Presentation
  東京都渋谷区
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] 細胞システムのロバストネス解析 ~酵母細胞をモデル系として~2009
- Author(s)
  守屋央朗
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PUBLICLY-21114515
[Presentation] タンパク質過剰がもたらす細胞毒性のモデルタンパク質を用いた解析
- Author(s)
  金高令子、蒔苗浩司、守屋央朗
- Organizer
  酵母遺伝学フォーラム第47回研究報告会
- Place of Presentation
  東京都・文京区
- Year and Date
  2014-09-01 – 2014-09-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] タンパク質過剰がもたらす細胞毒性のモデルタンパク質を用いた解析
- Author(s)
  金高令子、蒔苗浩司、守屋央朗
- Organizer
  酵母遺伝学フォーラム第47回研究報告会
- Place of Presentation
  東京大学弥生講堂
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質過剰がもたらす細胞毒性のモデルタンパク質を用いた解析
- Author(s)
  金高令子、蒔苗浩司、守屋央朗
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] タンパク質過剰がもたらす細胞毒性のモデルタンパク質を用いた解析
- Author(s)
  金高令子、蒔苗浩司、守屋央朗
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717
[Presentation] タンパク質過剰がもたらす細胞毒性のモデルタンパク質を用いた解析
- Author(s)
  金高令子、蒔苗浩司、守屋央朗
- Organizer
  第32回Yeast Workshop
- Place of Presentation
  広島県呉市
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-25640115
[Presentation] Evaluation of cytotoxicity caused by overproduction of localized signal attached GFPs
- Author(s)
  Reiko Kintaka, Koji Makanae, Hisao Moriya
- Organizer
  Yeast genetics meeting 2014
- Place of Presentation
  Seattle, USA
- Year and Date
  2014-07-29 – 2014-08-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-25108717

1. MAKINO Takashi (20443442)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. YAMAMOTO Yoshitaka (30550793)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KITO Keiji (40345632)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 根本理子 (30625926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Kawata Masakado (90204734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Nakamura Yoshimasa (60324381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Kano Jun (50375408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤あやの (40303002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中村俊之 (90706988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 竹田哲也 (30302368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤伸 (90512004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Boone Charles

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Knop Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 石川格靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 北野宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 佐藤道大

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Moriya Hisao 守屋 央朗

MORIYA Hisao 守屋 央朗

Research Projects

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ヒザラガイの磁鉄鉱歯形成機構の解明

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タンパク質の限界発現が発生させる細胞状態の解析Principal Investigator

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Unraveling the comprehensive picture of expression constraints mechanisms with the new expression system gTOW2.0Principal Investigator

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Cellar differentiation on the electronic semiconductor device induced by the electric stimulation

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連続するアミノ酸（PolyX）が生み出す細胞毒性のメカニズムPrincipal Investigator

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ヒザラガイの磁鉄鉱歯特異的な歯舌マトリックスタンパク質の機能解明

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発現量揺らぎ－適応系により探索する発現変動の適応－進化への影響Principal Investigator

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Mechanism of growth inhibition by overexpression explored from the expression level of the limiting mutant proteinPrincipal Investigator

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Cell processing capacity explored by expression limits of proteinsPrincipal Investigator

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発現量揺らぎー適応系により探るプロテオームの制約条件とその適応ー進化への影響Principal Investigator

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Identification and characterization of phytochemical-targeted genes using a genome wide yeast screening system

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Systematic analysis of proteins that cause overload of transport resources due to overexpressionPrincipal Investigator

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Analysis of mechanisms avoiding stoichometry imbalance(Fostering Joint International Research)Principal Investigator

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Moriya Hisao 守屋央朗

MORIYA Hisao 守屋央朗