Hayashi Toshihiro 林俊宏

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Toshihiro Hayashi 林俊宏

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Researcher Number	60505890
Other IDs	https://orcid.org/0000-0003-4362-7439
Affiliation (Current)	2026: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 帝京大学, 医学部, 教授 2017 – 2018: 帝京大学, 医学部, 教授 2016: 東京大学, 医学部附属病院, 講師 2015: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Neurology Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 46030:Function of nervous system-related
Keywords	Principal Investigator アルツハイマー病 / 脳内環境 / アドレナリン作動性神経 / モノアミン系神経伝達物質 / Neuroimaging / norepinephrine / Alzheimer's disease / 安静時fMRI / 神経機能画像法 Except Principal Investigator 脳内伝播 … More / 輸送機構 / タウ / エクソソーム / アルツハイマー病 / 可塑性 / 運動学習 / 細胞間ネットワーク / 小細胞系 / 赤核 / 選択的細胞除去法 / イムノトキシン / 光遺伝学的刺激法 / 脊髄投射 / 下オリーブ核投射 / 光遺伝学的刺激 / 脊髄 / DeepLabCut / ホールセル記録 / 光・化学遺伝学的操作法 / ３次元画像解析 / 組織透明化 / 視床後核 / 下オリーブ核 / 赤核回路網 Less

赤核大細胞・小細胞における上肢運動情報のクロスオーバー
- Principal Investigator
  
  大野孝恵
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Teikyo University
エクソソームの輸送先選択性に基づきタウの伝播阻止を目指すアルツハイマー病治療
- Principal Investigator
  
  磯尾紀子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Teikyo University
The effect of locus coeruleus-noradrenergic dysfunction on brain environment in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Hayashi Toshihiro
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Teikyo University
Resting state functional MRI as imaging biomarker for preclinical Alzheimer diseasePrincipal Investigator
- Principal Investigator
  
  Toshihiro Hayashi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Teikyo University
  The University of Tokyo

All 2024 2023 2022 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Soluble form of the APP fragment, sAPPβ, positively regulates tau secretion2023
- Author(s)
  Sato Haruaki、Kasuga Kensaku、Isoo Noriko、Hayashi Toshihiro、Ikeuchi Takeshi、Hori Yukiko、Tomita Taisuke
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 63-70
- DOI
  10.1016/j.neures.2023.03.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07744, KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-22KJ0968, KAKENHI-PLANNED-22H05036, KAKENHI-PROJECT-23H00394
[Journal Article] Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture2022
- Author(s)
  Kameda Hiroshi、Murabe Naoyuki、Mizukami Hiroaki、Ozawa Keiya、Hayashi Toshihiro、Sakurai Masaki
- Journal Title
  
  Journal of Comparative Neurology
  
  Volume: - Issue: 11 Pages: 1950-1965
- DOI
  10.1002/cne.25313
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06879, KAKENHI-PROJECT-20K07744
[Journal Article] Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study2022
- Author(s)
  Nishikawa N、Murata M、Hatano T、Mukai Y、Saitoh Y、Sakamoto T、Hanakawa T、Kamei Y、Tachimori H、Hatano K、Matsuda H、Taruno Y、Sawamoto N、Kajiyama Y、Ikenaka K、Kawabata K、Nakamura T、Iwaki H、Kadotani H、Sumi Y、Inoue Y、Hayashi T、Ikeuchi T、Shimo Y、Mochizuki H、Watanabe H、Hattori N、Takahashi Y、Takahashi R
- Journal Title
  
  Parkinsonism & Related Disorders
  
  Volume: 103 Pages: 129-135
- DOI
  10.1016/j.parkreldis.2022.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07744, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-22K18384, KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-21K19447, KAKENHI-PROJECT-19K16610, KAKENHI-PLANNED-19H05726, KAKENHI-PROJECT-23K21585, KAKENHI-PROJECT-23K21863
[Journal Article] Aphasic status epilepticus preceding tumefactive left hemisphere lesion in anti-MOG antibody associated disease2019
- Author(s)
  Katsuse Kazuto、Kurihara Masanori、Sugiyama Yusuke、Kodama Satoshi、Takahashi Miwako、Momose Toshimitsu、Yumoto Masato、Kaneko Kimihiko、Takahashi Toshiyuki、Kubota Akatsuki、Hayashi Toshihiro、Toda Tatsushi
- Journal Title
  
  Multiple Sclerosis and Related Disorders
  
  Volume: 27 Pages: 91-94
- DOI
  10.1016/j.msard.2018.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06159, KAKENHI-PROJECT-15K09348
[Journal Article] Longitudinally extensive vasogenic edema following spinal cord infarction2018
- Author(s)
  Gondo Takashi、Kurihara Masanori、Sugiyama Yusuke、Mano Tatsuo、Mori Harushi、Hayashi Toshihiro、Tsuji Shoji
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 6 Issue: 5 Pages: 143-145
- DOI
  10.1111/ncn3.12215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09348, KAKENHI-PROJECT-17K16113
[Journal Article] Reversible white matter lesions in ketotic-hyperglycemic seizure: metabolic and hemodynamic studies with MRI implied its reversibility.2018
- Author(s)
  Satoshi Kodama, Tatsuo Mano, Toshiyuki Kakumoto, Hiroyuki Ishiura, Akifumi Hagiwara, Kouhei Kamiya, Toshihiro Hayashi, Shoji Tsuji
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 印刷中 Pages: 20-21
- DOI
  10.1016/j.jns.2018.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16113, KAKENHI-PROJECT-15K09348
[Journal Article] Severe visual impairment and subclinical encephalitis preceding clinical signs of chondritis in relapsing polychondritis2018
- Author(s)
  Miyano Ryoji、Kurihara Masanori、Orimo Kenta、Mano Tatsuo、Kaburaki Toshikatsu、Tanaka Rie、Nishijima Hironobu、Ikemura Masako、Takahashi Miwako、Mori Harushi、Mutoh Tatsuro、Hamada Masashi、Hayashi Toshihiro、Toda Tatsushi
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 7 Issue: 2 Pages: 75-77
- DOI
  10.1111/ncn3.12243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0448, KAKENHI-PROJECT-15K09348, KAKENHI-PROJECT-15K20185, KAKENHI-PROJECT-17K16113, KAKENHI-PROJECT-18K16832
[Journal Article] “Localized” chronic invasive fungal rhinosinusitis without serological abnormalities2018
- Author(s)
  Uchigami Hirokazu、Sato Kenichiro、Kubota Akatsuki、Hayashi Toshihiro、Shimizu Jun、Ikemura Masako、Toda Tatsushi
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 7 Issue: 2 Pages: 96-97
- DOI
  10.1111/ncn3.12252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09348
[Journal Article] Novel De Novo KCND3 Mutation in a Japanese Patient with Intellectual Disability, Cerebellar Ataxia, Myoclonus, and Dystonia2017
- Author(s)
  Kurihara Masanori、Ishiura Hiroyuki、Sasaki Takuya、Otsuka Juuri、Hayashi Toshihiro、Terao Yasuo、Matsukawa Takashi、Mitsui Jun、Kaneko Juntaro、Nishiyama Kazutoshi、Doi Koichiro、Yoshimura Jun、Morishita Shinichi、Shimizu Jun、Tsuji Shoji
- Journal Title
  
  Cerebellum
  
  Volume: 17 Issue: 2 Pages: 237-242
- DOI
  10.1007/s12311-017-0883-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09347, KAKENHI-PROJECT-15K09348
[Journal Article] Recovered recall memory after decompression of the fornix by surgical removal of pineal tumor.2016
- Author(s)
  Yoshida, M., Hayashi, T., Fujii, K., Kawai, K., Tsuji, S., Iwata, A.
- Journal Title
  
  Neurology
  
  Volume: 86 Issue: 8 Pages: 790-791
- DOI
  10.1212/wnl.0000000000002394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09348
[Presentation] タウ内包細胞外小胞のマウス脳内における細胞間伝播.2024
- Author(s)
  澤重太洋，池末幾講，磯尾紀子，高木宏徳，吉田崇将，磯尾直之，堀由起子，富田泰輔，林俊宏
- Organizer
  第47回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07744
[Presentation] The red nucleus and its networks.2024
- Author(s)
  Takae Ohno, Hideo Miyake, Satoshi Fukuda, Naoyuki Murabe, Toshio Mitashita, Toshihiro Hayashi.
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07744
[Presentation] Uptake of tau-containing exosomes by neuronal cells.2022
- Author(s)
  Isoo, N, Kawata, K, Iso-o, N, Hori, Y, Tomita T, Hayashi T
- Organizer
  The 99th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-20K07744
[Presentation] 脳アミロイドアンギオパチーにおける皮質微小梗塞・白質病変の検討．2018
- Author(s)
  小林敬, 栗原正典, 神澤彩, 織茂賢太, 宮川統爾, 石浦浩之, 森墾, 林俊宏, 岩田淳, 戸田達史．
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-15K09348
[Presentation] 安静時fMRIと認知症の病態評価．2016
- Author(s)
  林　俊宏
- Organizer
  第40回日本高次脳機能障害学会学学術総会
- Place of Presentation
  松本
- Year and Date
  2016-11-11
- Invited
- Data Source
  KAKENHI-PROJECT-15K09348

1. 磯尾紀子 (90548330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 大野孝恵 (60508109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 福田諭 (50425641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮下俊雄 (80415314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村部直之 (90348813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 磯尾直之 (80420214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIURA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高橋浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 百瀬敏光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 間野達雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 西嶌大宣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 清水潤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Toshihiro 林 俊宏

Toshihiro Hayashi 林 俊宏

Research Projects

Research Products

Co-Researchers

赤核大細胞・小細胞における上肢運動情報のクロスオーバー

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エクソソームの輸送先選択性に基づきタウの伝播阻止を目指すアルツハイマー病治療

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of locus coeruleus-noradrenergic dysfunction on brain environment in Alzheimer's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Resting state functional MRI as imaging biomarker for preclinical Alzheimer diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Soluble form of the APP fragment, sAPPβ, positively regulates tau secretion2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aphasic status epilepticus preceding tumefactive left hemisphere lesion in anti-MOG antibody associated disease2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Longitudinally extensive vasogenic edema following spinal cord infarction2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reversible white matter lesions in ketotic-hyperglycemic seizure: metabolic and hemodynamic studies with MRI implied its reversibility.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Severe visual impairment and subclinical encephalitis preceding clinical signs of chondritis in relapsing polychondritis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] “Localized” chronic invasive fungal rhinosinusitis without serological abnormalities2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel De Novo KCND3 Mutation in a Japanese Patient with Intellectual Disability, Cerebellar Ataxia, Myoclonus, and Dystonia2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recovered recall memory after decompression of the fornix by surgical removal of pineal tumor.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] タウ内包細胞外小胞のマウス脳内における細胞間伝播.2024

Hayashi Toshihiro 林俊宏

Toshihiro Hayashi 林俊宏