Ooya Yoshihiro 大矢佳寛

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Oya Yoshihiro 大矢佳寛

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Researcher Number	60507218
Other IDs
Affiliation (Current)	2026: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), その他部局等, 室長
Affiliation (based on the past Project Information) *help	2025: 独立行政法人国立病院機構千葉医療センター千葉東病院(臨床研究部), その他部局等, 室長 2019 – 2024: 独立行政法人国立病院機構(千葉東病院臨床研究部), その他部局等, 室長
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator リンパ球 / 免疫抑制 / 制御性T細胞 / 免疫 / 樹状細胞 / 移植 / 自己免疫疾患 / 膠原病 / 免疫抑制療法

ヒト細胞を用いた未同定抗原に対する抗原特異的な免疫抑制療法の開発Principal Investigator
- Principal Investigator
  
  大矢佳寛
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  NHO Chiba Medical Center Chibahigashi National Hospital
関節組織を用いた未同定の抗原に対する抗原特異的免疫療法の開発Principal Investigator
- Principal Investigator
  
  大矢佳寛
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Hospital Organization Chiba-East-Hospital
Antigen specific immunosuppression for autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Oya Yoshihiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Hospital Organization Chiba-East-Hospital

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Polyclonally Derived Alloantigen-Specific T Regulatory Cells Exhibit Target-Specific Suppression and Capture MHC Class II from Dendritic Cells2024
- Author(s)
  Oya Yoshihiro、Tanaka Yasuyo、Nakazawa Takuya、Matsumura Ryutaro、Glass Deborah D、Nakajima Hiroshi、Shevach Ethan M
- Journal Title
  
  The Journal of Immunology
  
  Volume: 212 Issue: 12 Pages: 1891-1903
- DOI
  10.4049/jimmunol.2300780
- Data Source
  KAKENHI-PROJECT-22K07126
[Journal Article] Short-term and long-term outcomes of patients with anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis2024
- Author(s)
  Ida T, Furuta S, Fujiwara M, Hiraguri M, Hirose K, Ikeda K, Iwamoto T, Kagami SI, Kobayashi Y, Kurasawa K, Nakagomi D, Oya Y, Sanayama Y, Shimizu T, Tamachi T, Umibe T, Yasui M, Nakajima H.
- Journal Title
  
  Rheumatology(Oxford)
  
  Volume: in press Issue: 2 Pages: 756-762
- DOI
  10.1093/rheumatology/keae011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08211, KAKENHI-PROJECT-23K07891, KAKENHI-PROJECT-22K07126, KAKENHI-PROJECT-24K11349
[Journal Article] Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report2021
- Author(s)
  Yoshihiro Oya, Hidekazu Futami , Takuya Nakazawa , Kazuyuki Ishijima , Keiko Umemiya , Fumiyoshi Takizawa , Naoki Imai , Hiroshi Kitamura , Ryutaro Matsumura
- Journal Title
  
  J Med Case Rep.
  
  Volume: 15 Issue: 1 Pages: 482-496
- DOI
  10.1186/s13256-021-02909-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07616
[Journal Article] T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice2020
- Author(s)
  Makita S, Takatori H, Matsuki A, Kawashima, Iwata A, Tanaka S, Nakagomi D, Oya Y, Matsumura R, Tamachi T, Suto A, Suzuki K, Hirose K, Nakajima H
- Journal Title
  
  J Invest Dermatol.
  
  Volume: Online ahead of print Issue: 5 Pages: 1274-1285
- DOI
  10.1016/j.jid.2020.08.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08878, KAKENHI-PROJECT-18H02816, KAKENHI-PROJECT-19K17902, KAKENHI-PROJECT-21H02922, KAKENHI-PROJECT-19K07616, KAKENHI-PROJECT-21K08211, KAKENHI-PROJECT-21K08463
[Patent] インビトロでの制御性Ｔ細胞の特異性評価方法2019
- Inventor(s)
  大矢佳寛
- Industrial Property Rights Holder
  大矢佳寛
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K07616
[Patent] インビトロでの制御性Ｔ細胞の特異性評価方法2019
- Inventor(s)
  大矢佳寛、松村竜太郎
- Industrial Property Rights Holder
  大矢佳寛、松村竜太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] anti-EJ antibody positive polymyositis/dermatomyositis with interstitial pneumonia2024
- Author(s)
  二見秀一、大矢佳寛、若林豊、粕谷忠道、石島和幸、梅宮恵子、中澤卓也、松村竜太郎
- Organizer
  第68回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2024
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  第68回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Polyclonal iTreg mediated Target Specific Suppression2024
- Author(s)
  Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 53th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] 関節リウマチ診療データの後方視的解析2024
- Author(s)
  大矢佳寛・二見秀一・若林豊・粕谷忠道・石島和幸・梅宮恵子・中澤卓也・松村竜太郎
- Organizer
  臨床リウマチ学会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Plasticity in suppressive function of dendritic cells interacted with Treg cells2024
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Yutaka Wakabayashi, Tadamichi Kasuya, Yasuyo Tanaka, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach,
- Organizer
  The 73th Annual Meeting of Japanese Society of Allergology
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2024
- Author(s)
  Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 52th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Three cases of Interstitial pneumonia with anti-EJ positive polymyositis/dermatomyositis2024
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Yutaka Wakabayashi, Yousuke Toda, Kazuyuki Ishijima, Keiko Umemiya, Takuya Nakazawa, Ryutaro Matsumura
- Organizer
  第78回国立病院総合医学会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2023
- Author(s)
  Oya Yoshihiro
- Organizer
  The 52th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Plasticity of DC’s suppressive function and interaction with Treg cells2023
- Author(s)
  Yoshihiro Oya
- Organizer
  (FIMSA) Advanced Training Course 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Dual function of DC govern the Treg antigen specific suppression2023
- Author(s)
  Yoshihiro Oya,
- Organizer
  第72回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Foxp3+ Treg educated Dendritic cells have dual function for each different antigen2023
- Author(s)
  Yoshihiro Oya,
- Organizer
  第67回日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-22K07126
[Presentation] Recruitment of Treg cells by using irrelevant antigen is not enough to suppress T cell response to unknown antigens.2022
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 66th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] DC have dual function of T cell stimulation and T cell suppression for presented each antigen2022
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 51th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Tubulointerstitial nephritis and uveitis syndrome with persistent Toxoplasma IgM2022
- Author(s)
  Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Antigen specific Treg suppression can be mediated just by dendritic cells2021
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 70th Annual Meeting of Japanese Society of Allergology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Antigen specific suppression made on DC by Foxp3 Treg is not irreversible2021
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 65th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Recruitment of Foxp3 Treg is not sufficient to suppress target inflammation2021
- Author(s)
  Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Antigen specific suppression can be mediated through Antigen presenting cells in the absence of Treg cells2020
- Author(s)
  Oya Yoshihiro, Futami Hidekazu, Nakazawa Takuya, Matsumura Ryutaro, Nakajima Hiroshi, Shevach Ethan
- Organizer
  The 64th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Effector T cells are able to proliferate in the presence of activated non-congnate Foxp3+ Treg cells2020
- Author(s)
  Oya Yoshihiro, Futami Hidekazu, Nakazawa Takuya, Matsumura Ryutaro, Nakajima Hiroshi, Shevach Ethan
- Organizer
  JSA/WAO Joint Congress 2020-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Antigen-specific Foxp3+ Tregs suppress cognate antigen response but not suppress non-cognate antigen response.2019
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 63th Annual General Assembly and Scientific Meeting of the Japan College of Rheumatology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Treg mediate antigen specific suppression by capturing peptide-MHC from dendritic cell2019
- Author(s)
  Yoshihiro Oya
- Organizer
  The 301st Basic Research Joint Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Foxp3+ Tregs suppress cognate antigen response but not suppress non-cognate antigen response2019
- Author(s)
  Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 68th Annual Meeting of Japanese Society of Allegology
- Data Source
  KAKENHI-PROJECT-19K07616
[Presentation] Antigen-specific Foxp3+CD4+ Tregs suppress T cell response to cognate antigen but not suppress T cell response to non-cognate antigen in vivo2019
- Author(s)
  Yoshihiro Oya, Ryutaro Matsumura, Hiroshi Nakajima, Ethan Shevach
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K07616

1. SUTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. SUZUKI Kotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. HIROSE Kohichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 玉地智宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ooya Yoshihiro 大矢 佳寛

Oya Yoshihiro 大矢 佳寛

Research Projects

Research Products

Co-Researchers

ヒト細胞を用いた未同定抗原に対する抗原特異的な免疫抑制療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

関節組織を用いた未同定の抗原に対する抗原特異的免疫療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antigen specific immunosuppression for autoimmune diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Polyclonally Derived Alloantigen-Specific T Regulatory Cells Exhibit Target-Specific Suppression and Capture MHC Class II from Dendritic Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short-term and long-term outcomes of patients with anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice2020

Author(s)

Journal Title

DOI

Data Source

[Patent] インビトロでの制御性Ｔ細胞の特異性評価方法2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] インビトロでの制御性Ｔ細胞の特異性評価方法2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] anti-EJ antibody positive polymyositis/dermatomyositis with interstitial pneumonia2024

Author(s)

Organizer

Data Source

[Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2024

Author(s)

Organizer

Data Source

[Presentation] Polyclonal iTreg mediated Target Specific Suppression2024

Author(s)

Organizer

Data Source

[Presentation] 関節リウマチ診療データの後方視的解析2024

Author(s)

Organizer

Data Source

[Presentation] Plasticity in suppressive function of dendritic cells interacted with Treg cells2024

Author(s)

Organizer

Data Source

[Presentation] Phenotypic plasticity in suppressive function of dendritic cells mediated by Treg cells2024

Author(s)

Organizer

Data Source

[Presentation] Three cases of Interstitial pneumonia with anti-EJ positive polymyositis/dermatomyositis2024

Ooya Yoshihiro 大矢佳寛

Oya Yoshihiro 大矢佳寛