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Okamoto Koichi  岡本 耕一

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… Alternative Names

OKAMOTO Koichi  岡本 耕一

岡元 耕一  オカモト コウイチ

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Researcher Number 60531374
Affiliation (Current) 2025: 徳島大学, 病院, 講師
Affiliation (based on the past Project Information) *help 2016 – 2025: 徳島大学, 病院, 講師
2017: 徳島大学, 大学病院, 講師
2011 – 2012: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教
2010: 徳島大学, 病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related / Gastroenterology
Except Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
鋸歯状ポリポーシス症候群 / SPS / オルガノイド / BRAF / serrated pathway / 鋸歯状ポリープ / 腺腫 / 大腸癌 / メチル化 / 下部消化管学 … More / アポトーシス / Caspase8 / p62 / CRISPR Cas / p62 / オートファジー / p62 / DNAメチル化アレイ / SSA/P / ACF … More
Except Principal Investigator
オルガノイド / 膵癌 / exosome / 膵臓癌 / 大腸癌 / 癌 / 蛍光タイムラップス観察 / lentiviral vector / patient-derived organoid / 蛍光イメージング / 全ゲノム解析 / 染色体不安定性 / 癌関連脂肪細胞 / 脂肪細胞 / miRNA / 薬理学 / マイクロアレイ / Connectivity map解析 / 腺腫 / 癌予防 / 予防薬 / SSA/P / 大腸腺腫 / 大腸癌予防薬 / 光免疫療法 / 光免疫治療 / 光線免疫療法 / 分子イメージング / がん幹細胞 / 肝転移 / 超音波内視鏡下穿刺吸引術 / マイクロRNA / 蠕動音 / 腸電位 / 腸運動機能評価 / 過敏性腸症候群 / 下部消化管学(小腸、大腸) Less
  • Research Projects

    (12 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (15 People)
  •  Connectivity Map解析に基づいたGAPPS関連胃ポリープ及び癌予防薬の開発Principal Investigator

    • Principal Investigator
      岡本 耕一
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  Exosomeエンジニアリングによる膵癌とその微小環境の改変を標的とする治療法の開発

    • Principal Investigator
      佐藤 康史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  鋸歯状ポリポーシス症候群の左側及び右側大腸癌の分子生物学的差異の解析Principal Investigator

    • Principal Investigator
      岡本 耕一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  染色体不安定性に着目した大腸癌の抗癌剤耐性機序の解析

    • Principal Investigator
      高山 哲治
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  pancreatic cancer progression by cancer-associated adipocytes derived exosome

    • Principal Investigator
      SATO Yasushi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  Elucidation of carcinogenic mechanism for serrated polyposis syndromePrincipal Investigator

    • Principal Investigator
      OKAMOTO Koichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokushima
  •  Immunophoto therapy targeting cancer stem cell in colorectal cancer

    • Principal Investigator
      MUGURUMA Naoki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Development of chemopreventive agents using Connectivity Map analysis

    • Principal Investigator
      TAKAYAMA Tetsuji
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Development of new colorectal cancer treatment targeting p62Principal Investigator

    • Principal Investigator
      OKAMOTO Koichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Invetigation of molecular mechanism and new serum biomarker about liver metastasis with pancreatic cancer patients

    • Principal Investigator
      MIYAMOTO Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  大腸発癌におけるACF-SSA/P-cancer sequenceの証明Principal Investigator

    • Principal Investigator
      岡本 耕一
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima
  •  Development of a noninvasive colonic and small intestinal motility evaluation system for the diagnosis and optimum treatment of irritable bowel syndrome

    • Principal Investigator
      OKAHISA Toshiya
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018 2017 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Association of metabolic dysfunction‐associated steatotic liver disease with erosive esophagitis development: a longitudinal observational study2024

    • Author(s)
      Sogabe Masahiro、Okahisa Toshiya、Kagawa Miwako、Sei Motoko、Ueda Hiroyuki、Yokoyama Reiko、Kagemoto Kaizo、Tanaka Hironori、Kida Yoshifumi、Nakamura Fumika、Tomonari Tetsu、Okamoto Koichi、Kawano Yutaka、Miyamoto Hiroshi、Sato Yasushi、Nakasono Masahiko、Takayama Tetsuji
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: - Issue: 6 Pages: 1107-1114

    • DOI

      10.1111/jgh.16530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] A novel CT-based radiomics model for predicting response and prognosis of chemoradiotherapy in esophageal squamous cell carcinoma2024

    • Author(s)
      Kasai Akinari、Miyoshi Jinsei、Sato Yasushi、Okamoto Koichi、Miyamoto Hiroshi、Kawanaka Takashi、Tonoiso Chisato、Harada Masafumi、Goto Masakazu、Yoshida Takahiro、Haga Akihiro、Takayama Tetsuji
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 2039-2039

    • DOI

      10.1038/s41598-024-52418-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07084, KAKENHI-PROJECT-23K27588
  • [Journal Article] Association of metabolic dysfunction‐associated fatty liver disease with gallstone development: A longitudinal study2024

    • Author(s)
      Sogabe Masahiro、Okahisa Toshiya、Kagawa Miwako、Sei Motoko、Kagemoto Kaizo、Tanaka Hironori、Kida Yoshifumi、Nakamura Fumika、Tomonari Tetsu、Okamoto Koichi、Miyamoto Hiroshi、Sato Yasushi、Nakasono Masahiko、Takayama Tetsuji
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 39 Issue: 4 Pages: 754-761

    • DOI

      10.1111/jgh.16483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] Gastric fundic gland polyposis and cancer development after eradication of Helicobacter pylori in patient with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)2024

    • Author(s)
      Okamoto Koichi、Kawaguchi Tomoyuki、Kagemoto Kaizo、Kida Yoshifumi、Mitsui Yasuhiro、Nakamura Fumika、Yoshikawa Kozo、Sogabe Masahiro、Sato Yasushi、Shunto Joji、Bando Yoshimi、Shimada Mitsuo、Takayama Tetsuji
    • Journal Title

      Gastric Cancer

      Volume: 27 Issue: 3 Pages: 635-640

    • DOI

      10.1007/s10120-024-01473-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] Clinical Features and Outcomes of Conversion Therapy in Patients with Unresectable Hepatocellular Carcinoma2023

    • Author(s)
      Tomonari Tetsu、Tani Joji、Sato Yasushi、Tanaka Hironori、Tanaka Takahiro、Taniguchi Tatsuya、Kawano Yutaka、Morishita Asahiro、Okamoto Koichi、Sogabe Masahiro、Miyamoto Hiroshi、Masaki Tsutomu、Takayama Tetsuji
    • Journal Title

      Cancers

      Volume: 15 Issue: 21 Pages: 5221-5221

    • DOI

      10.3390/cancers15215221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] Novel Biomarkers of Gastric Cancer: Current Research and Future Perspectives2023

    • Author(s)
      Sato Yasushi、Okamoto Koichi、Kawano Yutaka、Kasai Akinari、Kawaguchi Tomoyuki、Sagawa Tamotsu、Sogabe Masahiro、Miyamoto Hiroshi、Takayama Tetsuji
    • Journal Title

      Journal of Clinical Medicine

      Volume: 12 Issue: 14 Pages: 4646-4646

    • DOI

      10.3390/jcm12144646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] Clinical Outcomes of Comprehensive Genomic Profiling Tests for Gastrointestinal Cancers: Experience from Tokushima University Hospital2023

    • Author(s)
      Sato Yasushi、Okada Yasuyuki、Fujino Yasuteru、Kawaguchi Tomoyuki、Kida Yoshifumi、Mitsui Yasuhiro、Tanaka Hironori、Tomonari Tetsu、Kitamura Shinji、Okamoto Koichi、Kawano Yutaka、Miyamoto Hiroshi、Sogabe Masahiro、Takayama Tetsuji
    • Journal Title

      J. Med. Invest.

      Volume: 70 Issue: 1.2 Pages: 154-159

    • DOI

      10.2152/jmi.70.154

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27588
  • [Journal Article] Lansoprazole inhibits the development of sessile serrated lesions by inducing G1 arrest via Skp2/p27 signaling pathway2023

    • Author(s)
      Kawaguchi Tomoyuki、Okamoto Koichi、Fujimoto Shota、Bando Masahiro、Wada Hironori、Miyamoto Hiroshi、Sato Yasushi、Muguruma Naoki、Horimoto Katsuhisa、Takayama Tetsuji
    • Journal Title

      Journal of Gastroenterology

      Volume: 59 Issue: 1 Pages: 11-23

    • DOI

      10.1007/s00535-023-02052-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-23K27588
  • [Journal Article] Colorectal carcinoma occurring via the adenoma?carcinoma pathway in patients with serrated polyposis syndrome2022

    • Author(s)
      Nakamura Fumika、Sato Yasushi、Okamoto Koichi、Fujino Yasuteru、Mitsui Yasuhiro、Kagemoto Kaizo、Kawaguchi Tomoyuki、Miyamoto Hiroshi、Muguruma Naoki、Sonoda Tomoko、Tsuneyama Koichi、Takayama Tetsuji
    • Journal Title

      Journal of Gastroenterology

      Volume: 57 Issue: 4 Pages: 286-299

    • DOI

      10.1007/s00535-022-01858-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08471
  • [Journal Article] EGFR-targeted molecular imaging of colorectal tumors: detection and treatment evaluation of tumors in animal models2019

    • Author(s)
      Miyamoto Y, Muguruma N, Fujimoto S, Okada Y, Kida Y, Nakamura F, Tanaka K, Nakagawa T, Kitamura S, Okamoto K, Miyamoto H, Sato Y, Takayama T.
    • Journal Title

      Cancer Science

      Volume: in press Issue: 6 Pages: 1921-1930

    • DOI

      10.1111/cas.14020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Journal Article] Detection of aberrant crypt foci with image-enhanced endoscopy2018

    • Author(s)
      Kagemoto K, Okamoto K, Takaoka T, Sato Y, Kitamura S, Kimura T, Sogabe M, Miyamoto H, Muguruma N, Tsuneyama K, Takayama T.
    • Journal Title

      Endoscopy International Open

      Volume: 8 Issue: 08 Pages: E924-E933

    • DOI

      10.1055/a-0621-8794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Journal Article] 大腸癌の疫学と基礎 大腸鋸歯状病変のメカニズム2017

    • Author(s)
      岡本耕一,川口智之,影本開三,藤本大策,六車直樹,高山哲治
    • Journal Title

      臨床消化器病

      Volume: 32 Pages: 818-824

    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Journal Article] Molecular imaging of aberrant crypt foci in the human colon targeting glutathione S-transferase P1-12017

    • Author(s)
      Naoki Muguruma, Koichi Okamoto, Tadahiko Nakagawa, Katsutaka Sannomiya, Shota Fujimoto, Yasuhiro Mitsui, Tetsuo Kimura, Hiroshi Miyamoto, Jun Higashijima, Mitsuo Shimada, Yoko Horino, Shinya Matsumoto, Kenjiro Hanaoka, Tetsuo Nagano, Makoto Shibutani, Tetsuji Takayama
    • Journal Title

      Sci. Rep.

      Volume: 7 Issue: 1 Pages: 6536-6536

    • DOI

      10.1038/s41598-017-06857-x

    • NAID

      120006535003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-17H04163
  • [Presentation] Serrated polyposis syndromeの右側及び左側大腸病変の臨床病理学的および分子生物学的解析2024

    • Author(s)
      岡本耕一、勢井萌都子、藤本将太、三橋威志、吉本貴則、川口智之、影本開三、喜田慶史、三井康裕、中村文香、佐藤康史、高山哲治
    • Organizer
      第10回消化管ポリポーシス研究会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07986
  • [Presentation] Serrated polyposis syndrome に合併した左側及び右側大腸腺腫の臨床病理学的特徴2023

    • Author(s)
      岡本耕一、中村文香、高山哲治
    • Organizer
      第109回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-22K07986
  • [Presentation] Serrated polyposis syndrome に合併した大腸腺腫 の臨床病理学的特徴2023

    • Author(s)
      岡本耕一、中村文香、八木麻衣、岡田明子、藤井祥平、吉本貴則、横山怜子、川口智之、影本開三、喜田慶史、三井康裕、佐藤康史、高山哲治
    • Organizer
      第98回大腸癌研究会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07986
  • [Presentation] バイオマーカー研究とその臨床的応用 右側大腸癌におけるTIMP1の予後不良因子としての意義 右側及び左側大腸癌を比較して2023

    • Author(s)
      上田 浩之, 川口 智之, 和田 浩典, 中村 文香, 北村 晋志, 岡本 耕一, 佐藤 康史, 高山 哲治
    • Organizer
      第19回日本消化管学会
    • Data Source
      KAKENHI-PROJECT-23K24321
  • [Presentation] Serrated polyposis syndrome に合併した左側及び右側大腸癌の臨床病理学的特徴ならびに発癌機序の解析2022

    • Author(s)
      岡本耕一 中村文香 高山哲治
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19K08471
  • [Presentation] Serrated polyposis syndrome に合併した大腸癌の臨床病理学的特徴ならびに発癌機序の検討2021

    • Author(s)
      中村文香、岡本耕一、影本開三、喜田慶史、田中久美子、北村晋志、佐藤康史、宮本弘志、六車直樹、高山哲治
    • Organizer
      GI week 第17回消化管学会総会
    • Data Source
      KAKENHI-PROJECT-19K08471
  • [Presentation] Serrated polyposis syndromeの臨床病理学的特徴ならびに発癌機序の検討2020

    • Author(s)
      中村文香、岡本耕一、影本開三、田中久美子、藤野泰輝、北村晋志、佐藤康史、宮本弘志、六車直樹、高山哲治
    • Organizer
      第16回日本消化管学会総会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08471
  • [Presentation] 新規蛍光プローブIndocyanine green (ICG) 標識Dasatinibを用いた消化管間質腫瘍 (GIST) の近赤外蛍光 イメージング2019

    • Author(s)
      藤本将太, 六車直樹, 中尾允泰, 安藤英紀, 宮本佳彦, 岡本耕一, 佐藤康史, 石田竜 弘, 佐野茂樹, 高山哲治
    • Organizer
      第14回日本分子イメージング学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Presentation] microRNA arrayを用いた大腸粘膜下層浸潤癌リンパ節転移に関わるバイオマーカーの同定及び機能解析2018

    • Author(s)
      3)藤野泰輝, 岡本耕一, 六車直樹, 三井康裕, 北村晋志, 藤本大策, 曽我部正弘, 宮本弘志, 佐藤康史, 高山哲治
    • Organizer
      第14回日本消化管学会総会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Presentation] Detection of Aberrant Crypt Foci Using Image-Enhanced Endoscopy.2017

    • Author(s)
      7)Kagemoto K, Okamoto K, Takaoka T, Okada Y, Tanaka K, Hirao A, Kitamura S, Kimura T, Miyamoto H, Muguruma N, Okahisa T, Tsuneyama K, Takayama T.
    • Organizer
      Digestive Disease Week 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04163
  • [Presentation] SSA/Pの拡大内視鏡所見と遺伝子異常の解析2012

    • Author(s)
      岡本耕一
    • Organizer
      第98回日本消化器病学会総会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2012-04-19
    • Data Source
      KAKENHI-PROJECT-24590942
  • [Presentation] 腸電位測定による簡便かつ非侵襲的大腸運動機能評価法の確立2011

    • Author(s)
      岡久稔也、梶雅子、岡本耕一、岡村誠介、高山哲治
    • Organizer
      第7回日本消化管学会総会学術集会(コアシンポジウム)機能性消化管疾患:病態にせまる~運動からみて~
    • Place of Presentation
      京都
    • Year and Date
      2011-02-11
    • Data Source
      KAKENHI-PROJECT-22659149
  • [Presentation] 腸電位測定による簡便かつ非侵襲的大腸運動機能評価法の確立2011

    • Author(s)
      岡久稔也、梶雅子、岡本耕一、岡村誠介、高山哲治
    • Organizer
      第7回日本消化管学会総会学術集会
    • Place of Presentation
      コアシンポジウム、国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-22659149
  • [Presentation] Usefulness of electrocolonography for evaluation of colonic motility2010

    • Author(s)
      Masako Kaji, Tetsu Tomonari, Miwako Kagawa, Azusa Saito, Miho Tsuda, Rie Harada, Tetsuo Kimura, Shinji Kitamura, Hiromi Yano, Koichi Okamoto, Miyako Niki, Toshiya Okahisa, Seisuke Okamura and Tetsuji Takayama
    • Organizer
      Digestive Disease Week2010
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-22659149
  • 1.  TAKAYAMA Tetsuji (10284994)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 19 results
  • 2.  MUGURUMA Naoki (90325283)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 9 results
  • 3.  SATO Yasushi (80343383)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 4.  MIYAMOTO Hiroshi (90398024)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  岡田 泰行 (60815447)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  OKAHISA Toshiya (60304515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  AKUTAGAWA Masatake (90294727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  EMOTO Takahiro (90418989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  北村 晋志 (60564490)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  武藤 倫弘 (30392335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  堀本 勝久 (40238803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  三好 人正 (00814625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  中村 文香 (70793743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 14.  HAGA Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  花岡 健二郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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