HARA Yuichi 原裕一

Researcher Number	60550952
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 川崎医科大学, 医学部, 特任研究員 2012 – 2020: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator ミトコンドリア / マイトファジー / mitophagy / バイオマーカー / ミトコンドリアフェリチン / FTMT / HCC / mitochondria / 鉄 / 鉄キレート … More / NASH / Mitophagy / オートファジー / C型肝炎ウイルス / Parkin / 酸化ストレス / 肝発癌 / HCV … More Except Principal Investigator 活性酸素種 / C型肝炎ウイルス / 酸化ストレス / ミトコンドリア / マイトファジー / 鉄 / autophagy / Parkin / mitophagy / 肝細胞癌 / Ｃ型肝炎ウイルス / drug delivery system / 2-Deoxy-D-Glucose / PLGA / ２DG / 抗腫瘍免疫 / 2DG-PLGA-NP / 2-Deoxy-D-Glucose（2DG） / 解糖系阻害剤 / 腫瘍免疫 / ナノ粒子 / ドラッグデリバリー / 解糖系 / がん / リン酸化シグナル / リン酸化 / 肝癌 / ミトコンドリアフェリチン / オートファジー / 細胞内シグナル / エストロゲン / 性差 / 肝発がん Less

Elucidation of the mechanism of hepatocarcinogenesis suppression by mitochondrial ferritinPrincipal Investigator
- Principal Investigator
  
  HARA YUICHI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kawasaki Medical School
Development of an anticancer therapy against liver cancer using 2-deoxy-D-glucose encapsulated in polymer poly (lactic-co-glycolic acid) nanoparticles
- Principal Investigator
  
  Nishina Sohji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kawasaki Medical School
Iron loss-induced mitophagy via mitochondria ferritin suppresses NASH-related hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  HARA YUICHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
Investigation of hepatocarcinogenic mechanisms by comprehensive ahalysis of cellular signaling responding to oxidative stress
- Principal Investigator
  
  Hino Keisuke
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
Restoration of mitophagy as a strategy for inhibiting hepatocarcinogenesis
- Principal Investigator
  
  HINO Keisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.Principal Investigator
- Principal Investigator
  
  HARA Yuichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
Analysis of hepatocarcinogenesis based on gender and mitochondrial biogenesis
- Principal Investigator
  
  HINO Keisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] The liver in systemic diseases2016
- Author(s)
  Keisuke Hino, Masaru Harada
- Total Pages
  343
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26293179
[Book] The Liver Cancer Journal2015
- Author(s)
  日野啓輔, 原　裕一
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24659377
[Book] C型肝炎の診療を極める基本から最前線まで2014
- Author(s)
  原裕一, 日野啓輔
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23390201
[Book] 酸化ストレスの医学2014
- Author(s)
  原　裕一　日野啓輔
- Total Pages
  280
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24659377
[Book] 酸化ストレスの医学2014
- Author(s)
  原裕一, 日野啓輔
- Total Pages
  444
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26293179
[Book] HEPATOLOGY　PRACTICE（第３巻）2014
- Author(s)
  原裕一, 日野啓輔
- Total Pages
  321
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25670374
[Book] HEPATOLOGY　PRACTICE（第３巻）2014
- Author(s)
  原裕一, 日野啓輔
- Total Pages
  321
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-26293179
[Book] 酸化ストレスの医学2014
- Author(s)
  原裕一, 日野啓輔
- Total Pages
  444
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25670374
[Book] C型肝炎の診療を極める2013
- Author(s)
  原　裕一日野啓輔
- Total Pages
  320
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24659377
[Book] 診断と治療　ウイルス肝炎の新展開2013
- Author(s)
  原　裕一、日野啓輔
- Total Pages
  190
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-23390201
[Book] 診断と治療　ウイルス肝炎の新展開2013
- Author(s)
  原　裕一、日野啓輔
- Total Pages
  190
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25670374
[Book] 消化器の臨床2012
- Author(s)
  原　裕一
- Total Pages
  120
- Publisher
  ヴァンメディカル
- Data Source
  KAKENHI-PROJECT-24659377
[Book] 肝発癌のすべて2012
- Author(s)
  原　裕一
- Total Pages
  444
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-24659377
[Book] C型肝炎のすべて2012
- Author(s)
  原　裕一
- Total Pages
  385
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-24659377
[Journal Article] Long-term phlebotomy successfully alleviated hepatic iron accumulation in a ferroportin disease patient with a mutation in SLC40A1: A case report.2021
- Author(s)
  Nishina S, Tomiyama Y, Ikuta K, Tatsumi Y, Toki Y, Kato A, Kato K, Yoshioka N, Sasaki K, Hara Y, Hino K.
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 21(1) Issue: 1 Pages: 111-111
- DOI
  10.1186/s12876-021-01674-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08347, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-21K07995
[Journal Article] Correlation of hepatitis C virus-mediated endoplasmic reticulum stress with autophagic flux impairment and hepatocarcinogenesis2021
- Author(s)
  Honma Yuichi、Miyagawa Koichiro、Hara Yuichi、Hayashi Tsuguru、Kusanaga Masashi、Ogino Noriyoshi、Minami Sota、Oe Shinji、Ikeda Masanori、Hino Keisuke、Harada Masaru
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: - Issue: 2 Pages: 108-121
- DOI
  10.1007/s00795-020-00271-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17037, KAKENHI-PROJECT-18K07988, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-21K07044, KAKENHI-PROJECT-21K07926, KAKENHI-PROJECT-21K07995
[Journal Article] Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice2021
- Author(s)
  Sasaki Kyo、Nishina Sohji、Yamauchi Akira、Fukuda Kotaro、Hara Yuichi、Yamamura Masahiro、Egashira Kensuke、Hino Keisuke
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 3 Pages: 739-762
- DOI
  10.1016/j.jcmgh.2020.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-18K07923, KAKENHI-PROJECT-21K07995
[Journal Article] Iron and liver cancer: an inseparable connection2021
- Author(s)
  Hino Keisuke、Yanatori Izumi、Hara Yuichi、Nishina Sohji
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 24 Pages: 7810-7829
- DOI
  10.1111/febs.16208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07309, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-21K07995
[Journal Article] Mitochondrial damage and iron metabolic dysregulation in hepatitis C virus infection2019
- Author(s)
  Hino K, Nishina S, Sasaki K, Hara Y
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 133 Pages: 193-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice2019
- Author(s)
  Nishina S, Yamauchi A, Kawaguchi T, Kaku K, Goto M, Sasaki K, Hara Y, Tomiyama Y, Kuribayashi F, Torimura T, Hino K.
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 5 Pages: 115-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] 特集Ⅱ　肝疾患におけるサルコペニアのメカニズム2019
- Author(s)
  原裕一、日野啓輔
- Journal Title
  
  消化器・肝臓内科　 Gastroenterology & hepatology
  
  Volume: 5 Pages: 92-97
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts the development of hepatocellular carcinoma in patients with non-alcoholic fatty liver disease.2018
- Author(s)
  Miwa Kawanaka, Yasuyuki Tomiyama, Hideyuki Hyogo, Masahiko Koda, Toshihide Shima, Hiroshi Tobita, Akira Hiramatsu, Ken Nishino, Toshiaki Okamoto, Shuichi Sato, Yuichi Hara, Sohji Nishina, Hirofumi Kawamoto, Kazuaki Chayama, Takeshi Okanoue, Keisuke Hino
- Journal Title
  
  Hepatology Research
  
  Volume: 48 Pages: 521-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] 肝炎と酸化ストレス2018
- Author(s)
  原　裕一, 日野啓輔
- Journal Title
  
  肝胆膵
  
  Volume: 77 Pages: 643-649
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] 1.Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts the development of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.2018
- Author(s)
  Miwa Kawanaka, Yasuyuki Tomiyama, Hideyuki Hyogo, Masahiko Koda, Toshihide Shima, Hiroshi Tobita, Akira Hiramatsu, Ken Nishino, Toshiaki Okamoto, Shuichi Sato, Yuichi Hara, Sohji Nishina, Hirofumi Kawamoto, Kazuaki Chayama, Takeshi Okanoue, Keisuke Hino.
- Journal Title
  
  Hepatol Res.
  
  Volume: 1 Issue: 7 Pages: 13054-13054
- DOI
  10.1111/hepr.13054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09384, KAKENHI-PROJECT-26293179
[Journal Article] A Series of microRNA in the Chromosome 14q32.2 Maternally Imprinted Region Related to Progression of Non-Alcoholic Fatty Liver Disease in a Mouse Model2016
- Author(s)
  Okamoto K, Koda M, Okamoto T, Onoyama T, Miyoshi K, Kishina M, Kato J, Tokunaga S, Sugihara TA, Hara Y, Hino K, Murawaki Y
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0154676-e0154676
- DOI
  10.1371/journal.pone.0154676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Journal Article] 【ミトコンドリアダイナミクスと疾患】肝疾患におけるマイトファジーの意義2016
- Author(s)
  原裕一, 日野啓輔
- Journal Title
  
  細胞
  
  Volume: 38(11) Pages: 534-537
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09384
[Journal Article] Branched-chain amino acids reduce hepatic iron accumulation and oxidative stress in hepatitis C virus polyprotein-expressing mice.2015
- Author(s)
  Korenaga M, Nishina S, Korenaga K, Tomiyama Y, Yoshioka N, Hara Y, Sasaki Y, Shimonaka Y, Hino K.
- Journal Title
  
  Liver Int.
  
  Volume: 35 Issue: 4 Pages: 1303-14
- DOI
  10.1111/liv.12675
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374, KAKENHI-PROJECT-25461019, KAKENHI-PROJECT-26293179
[Journal Article] Fibroblast activation protein-alpha-expressing fibroblasts promote the progression of pancreatic ductal adenocarcinoma2015
- Author(s)
  Kawase T, Yasui Y, Nishina S, Hara Y, Yanatori I, Tomiyama Y, Nakashima Y, Yoshida K, Kishi F, Nakamura M, Hino K
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 15 Issue: 1 Pages: 109-109
- DOI
  10.1186/s12876-015-0340-0
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Journal Article] Mitochondrial reactive oxygen species as a mystery voice in hepatitis C2014
- Author(s)
  Hino K, Hara Y, Nishina S
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Issue: 2 Pages: 123-32
- DOI
  10.1111/hepr.12247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374, KAKENHI-PROJECT-26293179
[Journal Article] Hepatic oxidative stress in ovariectomized transgenic mice expressing the hepatitis C virus polyprotein is augmented through suppression of AMPK/PGC-1alpha signaling2014
- Author(s)
  Tomiyama Y, Nishina S, Hara Y, Kawase T, Hino K
- Journal Title
  
  Hepatol Res
  
  Volume: (in press) Issue: 10 Pages: 229-39
- DOI
  10.1111/hepr.12254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374, KAKENHI-PROJECT-26293179
[Journal Article] Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.2014
- Author(s)
  Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K.
- Journal Title
  
  Am J Pathol. 2014
  
  Volume: 184 Issue: 11 Pages: 3026-39
- DOI
  10.1016/j.ajpath.2014.07.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-25293110
[Journal Article] Mitochondrial reactive oxygen species as a mystery voice in hepatits C2014
- Author(s)
  Hino K, Hara Y, Nishina S
- Journal Title
  
  Heparol Res
  
  Volume: 44 Pages: 123-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390201
[Journal Article] Clinical usefulness of non-protein respiratory quotient measurement in non-alcoholic fatty liver disease.2013
- Author(s)
  Keiko Korenaga , Masaaki Korenaga, Fusako Teramoto, Toshiko Suzuki,Sohoji Nishina, Kyo Sasaki, Yoshihiro Nakashima,Yasuyuki Tomiyama, Naoko Yoshioka, Yuichi Hara, Takuya Moriya, Keisuke Hino
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Pages: 1284-1294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659377
[Journal Article] Hepatic oxidative stress in ovariectomized transgenic mice expression the hepatitis C virus polyprotein is augmented through suppression of adenosine monophosphate-activated protein kinase/proliferator-activated receptor gamma co-activator 1 alpha signaling.2013
- Author(s)
  Yasuyuki Tomiyama Sohoji Nishina Yuichi hara Keisuke Hino
- Journal Title
  
  Hepatol Res
  
  Volume: １４ Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659377
[Journal Article] Clinical usefulness of non-protein respiratory quotient measurement in non-alcoholic fatty liver disease2013
- Author(s)
  Korenaga K1, Korenaga M, Teramoto F, Suzuki T, Nishina S, Sasaki K, Nakashima Y, Tomiyama Y, Yoshioka N, Hara Y, Moriya T, Hino K.
- Journal Title
  
  Hepatol Res.
  
  Volume: 43 Issue: 12 Pages: 1284-1294
- DOI
  10.1111/hepr.12095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461019, KAKENHI-PROJECT-25670374
[Journal Article] Iron metabolic disorder in chronic hepatitis C: Mechanisms and relevance to hepatocarcinogenesis2013
- Author(s)
  Hino K, Nishina S, Hara Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Suppl 4 Issue: S4 Pages: 93-8
- DOI
  10.1111/jgh.12243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374
[Journal Article] Iron metabolic disorder in chronic hepatitis C:Mechanisms and relevance to hepatocarcinogenesis.2013
- Author(s)
  Keisuke Hino, Sohoji Nishina, Yuichi hara
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Pages: 93-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659377
[Journal Article] Iron metabolic disorder in chronic hepatitis C. Mechanisms and relevance to hepatocarcinogenesis2013
- Author(s)
  Hino K, Nishina S, Hara Y
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28 Suppl 4 Pages: 93-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390201
[Journal Article] Risk factors for survival and the development of hepatocellular carcinoma in patients with primary biliary cirrhosis.2013
- Author(s)
  Tomiyama Yasuyuki,Kazuyuki Takenaka ,Takahiro Kodama,Miwa Kawanaka , Kyo Sasaki,Sohoji Nishina , Naoko Yoshioka, Yuichi Hara Y, Keisuke Hino
- Journal Title
  
  Hepatol Res
  
  Volume: 52 Pages: 1553-1559
- NAID
  130003365701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659377
[Journal Article] Risk factors for survival and the development of hepatocellular carcinoma in patients with primary biliary cirrhosis2013
- Author(s)
  Tomiyama Y, Takenaka K, Kodama T, Kawanaka M, sasaki K, Nishina S, Yoshioka N, Hara Y, Hino K
- Journal Title
  
  Intern Med
  
  Volume: 52 Pages: 1553-9
- NAID
  130003365701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390201
[Journal Article] Risk factors for survival and the development of hepatocellular carcinoma in patients with primary biliary cirrhosis2013
- Author(s)
  Tomiyama Y, Takenaka K, Kodama T, Kawanaka M, sasaki K, Nishina S, Yoshioka N, Hara Y, Hino K
- Journal Title
  
  Intern Med
  
  Volume: 52 Pages: 1553-9
- NAID
  130003365701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] Specific inhibition of cancer cell glycolysis enhances antitumor immunity in hepatocellular carcinoma2019
- Author(s)
  佐々木恭、仁科惣治、山内明、原裕一、福田宏太郎、日野啓輔
- Organizer
  APASL Single Topic Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07923
[Presentation] NAFLD進展・発癌抑制のためのミトコンドリア品質管理とその分子機構2019
- Author(s)
  原裕一, 田中敦, 佐々木恭, 仁科惣治, 日野啓輔
- Organizer
  第15回酸化ストレスと肝研究会
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Treatment of hepatocellular carcinoma using 2-Antitumor effects of 2-deoxy-D-glucose encapsulated PLGA nanoparticles against hepatocellular carcinoma in terms of tumor immunity2019
- Author(s)
  佐々木恭、仁科惣治、山内明、原裕一、福田宏太郎、日野啓輔
- Organizer
  American Association for the Study of Liver Diseases(AASLD) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07923
[Presentation] Mitophagy誘導機構の解明2018
- Author(s)
  原裕一, 佐々木恭, 仁科惣治, 日野啓輔
- Organizer
  第14回酸化ストレスと肝研究会
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] NAFLD 進展・発癌抑制のためのミトコンドリア品質管理とその分子機構2018
- Author(s)
  原裕一, 田中敦, 佐々木恭,仁科惣治, 日野啓輔
- Organizer
  肝類同壁細胞研究会構
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] 細胞内鉄欠乏によるミトコンドリア選択的オートファジーの分子機構2018
- Author(s)
  原裕一, 佐々木恭, 仁科惣治, 日野啓輔
- Organizer
  第42回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] 肝発癌抑制機構としてのmitophagy誘導2018
- Author(s)
  原　裕一、仁科惣治、日野啓輔
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] ミトコンドリア内鉄欠乏によるmitophagy 誘導機構2018
- Author(s)
  原　裕一, 仁科惣治, 日野啓輔
- Organizer
  第42回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] ミトコンドリア内鉄欠乏によるmitophagy誘導機構2017
- Author(s)
  原裕一, 佐々木恭, 仁科惣治, 日野啓輔a, Keisuke Hino
- Organizer
  AASLD2015(American Association for the Study of Liver Diseases2015)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Mitophagy誘導機構の解明2017
- Author(s)
  原裕一, 簗取いずみ, 日野啓輔
- Organizer
  JDDW2017 肝臓学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] ミトコンドリア内鉄欠乏によるmitophagy誘導機構2017
- Author(s)
  原　裕一、仁科惣治、日野啓輔
- Organizer
  第42回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] Loss of iron triggers mitophagy by inducing mitochondrial ferritin2017
- Author(s)
  Yuichi Hara, Kyo Sasaki, Soji Nishina, Keisuke Hino
- Organizer
  AASLD2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] LOSS OF IRON UPREGULATES MITOCHONDRIA FERRITIN AND TRIGGERS MITOPHAGY THROUGH THE BINDING OF MITOCHONDRIA FERRITIN TO NUCLEAR RECEPTOR COACTIVATOR 42017
- Author(s)
  Yuichi Hara, Izumi Yanatori, Kyo Sasaki, Sohji Nishina, Fumio Kishi, Keisuke Hino
- Organizer
  Seventh Congress of the International BioIron Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] NASH肝発癌抑制機構としてのmitophagy誘導2017
- Author(s)
  原裕一,仁科惣治, 日野啓輔
- Organizer
  第53回日本肝臓学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Los of iron up regulates mitochondria ferritin and triggers mitophagy2017
- Author(s)
  Hara Y, Sasaki K, Nishina S, Hino K
- Organizer
  The Annual Meeting of American Association for the Study of Liver Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] NASH肝発癌抑制機構としてのmitophagy誘導2017
- Author(s)
  原　裕一、仁科惣治、日野啓輔
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] 鉄キレートはC型肝炎ウイルスによるmitophagyの抑制を回復させる2016
- Author(s)
  原裕―, 仁科惣治, 日野啓輔
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉幕張メッセ
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] 鉄キレートはC型肝炎ウイルスによるmitophagyの抑制を回復させる2016
- Author(s)
  原裕―, 仁科惣治, 日野啓輔
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  幕張メッセ　千葉
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] 肝細胞癌進展抑制におけるDPP4阻害薬の分子学的機序2016
- Author(s)
  仁科惣治, 山内明, 富山恭行, 吉岡奈穂子, 原裕一, 日野啓輔
- Organizer
  JDDW2016
- Place of Presentation
  神戸ポートピアホテル
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] Comparison of therapeutic effect of sorafenib and drug eluting beads transcatheter arterial chemoembolization on hepatocellular carcinoma refractory to conventional transcatheter arterial chemoembolization2016
- Author(s)
  Yasuyuki Tomiyama, Naoko Yoshioka, Nobuko Koyama, Kyo Sasaki, Sohji Nishina, Yuichi Hara, Keisuke Hino
- Organizer
  the 12th JSH Single Topic Conference in Kanazawa
- Place of Presentation
  HOTEl nikko Kanazawa　Ｊａｐａｎ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] NASH肝発癌抑制機構としてのmitophagy誘導2016
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京京王プラザホテル
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] 肝細胞癌治療標的としてのCD26(DPP4) の意義2016
- Author(s)
  仁科惣治, 山内明, 小山展子, 富山恭行, 吉岡奈穂子, 原裕一, 日野啓輔
- Organizer
  第113回日本内科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] 鉄キレートはC型肝炎ウイルスによるmitophagyの抑制を回復させる2016
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Iron chelator suppresses hepatocarcinogenesis through mitophagy induction in STAM mice2016
- Author(s)
  Yuichi Hara, Kyo Sasaki, Soji Nishina, Keisuke Hino
- Organizer
  AASLD LiverLearning 2016
- Place of Presentation
  Boston,USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Dipeptidyl peptidase 4 (DPP4) inhibitor enhances natural killer cell chemotaxis, improving tumor immunity against hepatocellular carcinoma2016
- Author(s)
  Sohji Nishina, Akira Yamauchi, Yuichi Hara, Kyo Sasaki, Keisuke Hino
- Organizer
  Annual Meeting of AASLD
- Place of Presentation
  Boston（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] Dipeptidyl peptidase 4 (DPP4) inhibitor enhances natural killer cell chemotaxis, improving tumor immunity against hepatocellular carcinoma2016
- Author(s)
  Sohji Nishina, Akira Yamauchi, Yuichi Hara, Kyo Sasaki, Keisuke Hino
- Organizer
  AASLD LiverLearning 2016
- Place of Presentation
  Boston,USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09384
[Presentation] Iron chelator suppresses hepatocarcinogenesis through mitophagy induction in STAM mice2016
- Author(s)
  Yuichi Hara, Kyo Sasaki, Soji Nishina, Keisuke Hino
- Organizer
  Annual Meeting of AASLD
- Place of Presentation
  Boston（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] Iron chelation restores mitophagy suppressed by hepatitis C virus2015
- Author(s)
  Hara Y, Nishina S, Hirayama T, Nagasawa H, Hino K
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases 2015
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] DPP-4 inhibitor, anagliptin suppresses the progression of Hepatocellular carcinoma2015
- Author(s)
  Nishina S, Yamauchi A, Tomiyama Y, Hara Y, Hino K
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases 2015
- Place of Presentation
  San Francisco
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] HCVコアタンパクによるmitophagyの抑制2015
- Author(s)
  原裕一
- Organizer
  肝臓フォーラム（西部）
- Place of Presentation
  大阪市
- Year and Date
  2015-02-28
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin in the context of mitochondrial depolarization2014
- Author(s)
  Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K
- Organizer
  5th World Congress on Targeting Mitochondria
- Place of Presentation
  Ritz Carlton Hotel, Berlin, Germany
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] HCVとミトコンドリアのバイオジェネーシスとの関連性2014
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] HCVとミトコンドリアのバイオジェネーシスとの関連性2014
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ、東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] HCV とミトコンドリアバイオジェネシスとの関連性2014
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin in the context of mitochondrial depolarization2014
- Author(s)
  Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K
- Organizer
  5th World Congress on Targeting Mitochondria
- Place of Presentation
  Ritz Carlton Hotel, Berlin, Germany
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26293179
[Presentation] HCVとミトコンドリアのバイオジェネーシスとの関連性2014
- Author(s)
  原裕一, 仁科惣治, 日野啓輔
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ、東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin2013
- Author(s)
  Hara Y, Nishina S, Hino K, et al
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Suppressed mitophagy in transgenic mice expressing hepatitis C virus polyprotein2013
- Author(s)
  Yuichi Hara, Izumi Yanatori , Emi Kiyokage , Sohji Nishina, Yasuyuki Tomiyama, Kazunori Toida , Masanori Ikeda , Fumio Kishi , Nobuyuki Kato , Michio Imamura , Kazuaki Chayama , Keisuke Hino
- Organizer
  The 2nd JSGE International Topic Conference
- Place of Presentation
  Kagosima castle park hotel,Kagoshima, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Hepatitis C virus core protein suppresses mitophagy2013
- Author(s)
  Yuichi Hara, Izumi Yanatori , Emi Kiyokage , Sohji Nishina, Yasuyuki Tomiyama, Kazunori Toida , Masanori Ikeda , Fumio Kishi , Nobuyuki Kato , Michio Imamura , Kazuaki Chayama , Keisuke Hino
- Organizer
  AASLD
- Place of Presentation
  Walter E. Washington Convention Center, Washington, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Ovariectomized transgenic mice expressing hepatitis C virus poltprotein develop hepatic steatosis through suppression of AMPK/PGCα signaling2013
- Author(s)
  Tomiyama Y, Nishina S, Hara Y, Hino K
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington DC
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Supressed Mitophagy in Transgenic mice Expressing Hepatitis C Virus Polyprotein2013
- Author(s)
  Yuichi Hara, Izumi Yanatori , Emi Kiyokage , Sohji Nishina, Yasuyuki Tomiyama, Kazunori Toida , Masanori Ikeda , Fumio Kishi , Nobuyuki Kato , Michio Imamura , Kazuaki Chayama , Keisuke Hino
- Organizer
  Cell Symposia : Mitochondria
- Place of Presentation
  Rua Latino Coelho, 1Lisbon,Portugal
- Invited
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] HCVコア蛋白とParkinとの相互作用によるマイトファジーの抑制2013
- Author(s)
  原　裕一仁科惣治
- Organizer
  DDW
- Place of Presentation
  グランドプリンスホテル、東京、日本
- Invited
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] The hepatitis C virus core protein suppresses mitophagy by interacting with Parkin2013
- Author(s)
  Hara Y, Nishina S, Hino K, et al
- Organizer
  Cell symposium Mitochondria : from signaling to disease
- Place of Presentation
  Lisbon
- Year and Date
  2013-05-05
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Supressed Mitophagy in Transgenic moice Expressing Hepatitis C Virus Polyprotein2013
- Author(s)
  Hara Yuichi
- Organizer
  The 2nd JSGE International Topic Conference
- Place of Presentation
  shiroyamakankohotel, kagoshima
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] HCVコア蛋白とParkinとの相互作用よるmitophagyの抑制及びHCV増殖に対する影響2013
- Author(s)
  原　裕一　仁科惣治　日野啓輔
- Organizer
  日本肝臓学会西部会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル,岐阜、日本
- Invited
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Hepatitis C Virus core protein supress mitophagy by interacting with Parkin2012
- Author(s)
  Hara Yuichi
- Organizer
  International symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Palazzo del cinema,Lido-Venice,Italy
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Hepatitis C Virus proteins supress mitophagy by interacting with Parkin2012
- Author(s)
  Hara Yuichi
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin2012
- Author(s)
  Hara Yuichi
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Hepatitis C Virus core protein supress mitophagy by interacting with Parkin2012
- Author(s)
  Hara Yuichi
- Organizer
  JSH Single Topic Conference
- Place of Presentation
  Keioplazahotel,Tokyo
- Data Source
  KAKENHI-PROJECT-24659377
[Presentation] Splenectomy causes hepatic inflammation and oxidative stress through activation of Kupffer cells in iron-overloaded mice
- Author(s)
  Sohji Nishina, Yuichi Hara, Yasuyuki Tomiyama, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  WALTER E. Washington Convention Center Washington,DC.USA
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Ovariectomized transgenic mice expressing hepatitis C virus polyprotein develop hepatic steatosis through suppression of AMPK/PGC1a signaling
- Author(s)
  Yasuyuki Tomiyama, Sohji Nishina , Yuichi Hara, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Waltere Washington Convention Center, Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] HCVコア蛋白とParkinとの相互作用によるマイトファジーの抑制
- Author(s)
  原裕一，仁科惣治，日野啓輔
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Splenectomy causes hepatic inflammation and oxidative stress through activation of Kupffer cells in iron-overloaded mice
- Author(s)
  Sohji Nishina, Yuichi Hara, Yasuyuki Tomiyama, Keisuke Hino
- Organizer
  17th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka International Convention Center, Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] The hepatitis C virus core protein suppresses mitophagy by affecting Parkin
- Author(s)
  Yuichi Hara, Izumi Yanatori , Masanori Ikeda, Sohji Nishina, Yasuyuki Tomiyama, Fumio Kishi, Kazunori Toida, Nobuyuki Kato, Kazuaki Chayama , Keisuke Hino
- Organizer
  Cell Sumposium Mitochondria:from Signaling to Disease
- Place of Presentation
  Sheraton Lisbosa, Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] HCVタンパクはエストロゲン欠乏起因性酸化ストレスに対する抗酸化機構を抑制する
- Author(s)
  富山恭行，小山展子，佐々木恭，仁科惣治，吉岡奈穂子，原　裕一，日野啓輔
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Ovariectomized transgenic mice expressing hepatitis C virus polyprotein develop hepatic steatosis through suppression of AMPK/PGC1a signaling
- Author(s)
  Yasuyuki Tomiyama, Sohji Nishina , Yuichi Hara, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  WALTER E. Washington Convention Center Washington,DC.US
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] The hepatitis C virus core protein suppresses mitophagy by affecting Parkin
- Author(s)
  Yuichi Hara, Izumi Yanatori , Masanori Ikeda, Sohji Nishina, Yasuyuki Tomiyama, Fumio Kishi, Kazunori Toida, Nobuyuki Kato, Kazuaki Chayama , Keisuke Hino
- Organizer
  Cell Symposium Mitochondria:from Signaling to Disease
- Place of Presentation
  Sheraton Lisboa, Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] HCVコア蛋白とParkinとの相互作用によるマイトファジーの抑制
- Author(s)
  原裕一，仁科惣治，日野啓輔
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] Splenectomy causes hepatic inflammation and oxidative stress through activation of Kupffer cells in iron-overloaded mice
- Author(s)
  Sohji Nishina, Yuichi Hara, Yasuyuki Tomiyama, Keisuke Hino
- Organizer
  17th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka International Convention Center, osaka, Japan
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin
- Author(s)
  Yuhichi Hara, Izumi Yanatori, EmiKiyokage, Sohji Nishina, Yasuyuki Tomiyama, Kazunori Toida, Masanori Ikeda, Fumio Kishi, Nobuyuki Kato, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Waltere Washington Convention Center, Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] Hepatitis C virus core protein suppresses mitophagy by interacting with Parkin
- Author(s)
  Yuhichi Hara, Izumi Yanatori, EmiKiyokage, Sohji Nishina, Yasuyuki Tomiyama, Kazunori Toida, Masanori Ikeda, Fumio Kishi, Nobuyuki Kato, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  WALTER E. Washington Convention Center Washington,DC.US
- Data Source
  KAKENHI-PROJECT-23390201
[Presentation] Splenectomy causes hepatic inflammation and oxidative stress through activation of Kupffer cells in iron-overloaded mice
- Author(s)
  Sohji Nishina, Yuichi Hara, Yasuyuki Tomiyama, Keisuke Hino
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Waltere Washington Convention Center, Washington DC, USA
- Data Source
  KAKENHI-PROJECT-25670374
[Presentation] HCVタンパクはエストロゲン欠乏起因性酸化ストレスに対する抗酸化機構を抑制する
- Author(s)
  富山恭行，小山展子，佐々木恭，仁科惣治，吉岡奈穂子，原　裕一，日野啓輔
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-25670374

1. HINO Keisuke (80228741)

# of Collaborated Projects: 7 results

# of Collaborated Products: 89 results
2. NISHINA Sohji (70550961)

# of Collaborated Projects: 6 results

# of Collaborated Products: 74 results
3. IKEDA Masanori (30315767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. KISHI Fumio (40153077)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. KORENAGA Masaaki (70420536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. IKUTA Katsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. YAMAMURA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. YANATORI Izumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 土岐康通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 草永真志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山内明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HARA Yuichi 原 裕一

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of hepatocarcinogenesis suppression by mitochondrial ferritinPrincipal Investigator

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Development of an anticancer therapy against liver cancer using 2-deoxy-D-glucose encapsulated in polymer poly (lactic-co-glycolic acid) nanoparticles

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Iron loss-induced mitophagy via mitochondria ferritin suppresses NASH-related hepatocellular carcinomaPrincipal Investigator

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Investigation of hepatocarcinogenic mechanisms by comprehensive ahalysis of cellular signaling responding to oxidative stress

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Restoration of mitophagy as a strategy for inhibiting hepatocarcinogenesis

Principal Investigator

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Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.Principal Investigator

Principal Investigator

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Research Institution

Analysis of hepatocarcinogenesis based on gender and mitochondrial biogenesis

Principal Investigator

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[Book] The liver in systemic diseases2016

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[Book] The Liver Cancer Journal2015

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[Book] C型肝炎の診療を極める基本から最前線まで2014

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[Book] 酸化ストレスの医学2014

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[Book] 酸化ストレスの医学2014

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[Book] HEPATOLOGY PRACTICE（第３巻）2014

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[Book] HEPATOLOGY PRACTICE（第３巻）2014

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HARA Yuichi 原裕一

[Book] HEPATOLOGY　PRACTICE（第３巻）2014

[Book] HEPATOLOGY　PRACTICE（第３巻）2014

[Book] 診断と治療　ウイルス肝炎の新展開2013

[Book] 診断と治療　ウイルス肝炎の新展開2013

[Journal Article] 特集Ⅱ　肝疾患におけるサルコペニアのメカニズム2019