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Wakai Takuya  若井 拓哉

ORCIDConnect your ORCID iD *help
Researcher Number 60557768
Other IDs
Affiliation (Current) 2025: 岡山大学, 環境生命自然科学学域, 准教授
Affiliation (based on the past Project Information) *help 2023: 岡山大学, 環境生命自然科学学域, 准教授
2016 – 2023: 岡山大学, 環境生命科学研究科, 准教授
2021 – 2022: 岡山大学, 環境生命科学学域, 准教授
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Basic Section 44010:Cell biology-related / Obstetrics and gynecology
Except Principal Investigator
Basic Section 90110:Biomedical engineering-related / Basic Section 42040:Laboratory animal science-related / Basic Section 42010:Animal production science-related / Biomolecular chemistry and related fields / Obstetrics and gynecology
Keywords
Principal Investigator
マウス / ミトコンドリア / ライブセルイメージング / 加齢 / カルシウムシグナリング / 小胞体 / オルガネラ / 卵母細胞 / 染色体 / 不妊 … More / 微小核 / 酸化ストレス / 活性酸素 / 染色体異常 / 初期胚 / カルシウム / カルシウムシグナル / 動物 / 老化 / アクチンフィラメント / 減数分裂 / 卵成熟 / 受精 … More
Except Principal Investigator
細胞内カルシウム濃度 / 代謝 / ATP / 精子運動性 / マウス / 細胞外マトリックス / 突然変異 / 不妊 / ADAMTSL2 / ミュータントマウス / 下垂体 / 性成熟 / 卵巣 / ovary / Adamtsl2 / マイトファジー / ミトコンドリアDNA / オートファジー / 時空間的制御 / ミトコンドリア / 初期発生能 / 卵母細胞 / 発生 / 光制御 / 翻訳 / ケージドアミノアシルtRNA / 応用動物 / 細胞・組織 / 再生医学 / 発生・分化 / 移植・再生医療 / 卵巣凍結保存 Less
  • Research Projects

    (8 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (10 People)
  •  着床前胚発生における微小核形成へのミトコンドリア機能の関与Principal Investigator

    • Principal Investigator
      若井 拓哉
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Okayama University
  •  Studies on motility control mechanism of mammalian sprematozoa using ATP imaging

    • Principal Investigator
      松浦 宏治
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Okayama University of Science
  •  Regulation of ovarian function by Adamtsl2, a novel causative gene isolated from infertile mutant mice

    • Principal Investigator
      Tsuji takehito
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Okayama University
  •  Physiological analysis of the endoplasmic reticulum-mitochondria contact sites in oocytesPrincipal Investigator

    • Principal Investigator
      Wakai Takuya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Okayama University
  •  Creation of mammalian oocytes with high fertility by spatiotemporal regulation of the function of mitochondria

    • Principal Investigator
      FUNAHASHI Hiroaki
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42010:Animal production science-related
    • Research Institution
      Okayama University
  •  Photo-triggered translation using caged aminoacyl-tRNA in early embryos

    • Principal Investigator
      Ohtsuki Takashi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biomolecular chemistry and related fields
    • Research Institution
      Okayama University
  •  Organelle dynamics during meiotic maturation of mouse oocytesPrincipal Investigator

    • Principal Investigator
      Wakai Takuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Okayama University
  •  Cryopreservation of ovarian tissue

    • Principal Investigator
      Motohashi Hideyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tokyo Medical University
      Okayama University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

  • [Book] Encyclopedia of Reproduction (Second Edition)2018

    • Author(s)
      Wakai T., Mehregan A., Fissore R.A.(部分執筆)
    • Total Pages
      3868
    • Publisher
      Elsevier
    • ISBN
      9780128118993
    • Data Source
      KAKENHI-PROJECT-17K19202
  • [Book] Encyclopedia of Reproduction (Second Edition)2018

    • Author(s)
      Wakai T, Mehregan A, Fissore RA.
    • Total Pages
      3868
    • Publisher
      Academic Press
    • ISBN
      9780128118993
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Journal Article] Cell-cycle dependent GATA2 subcellular localization in mouse 2-cell embryos2021

    • Author(s)
      Komatsu Masaya, Tsukahara Hayato, Bai Hanako, Takahashi Masashi, Wakai Takuya, Kawahara Manabu
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 584 Pages: 1-6

    • DOI

      10.1016/j.bbrc.2021.10.077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-20K06627
  • [Journal Article] Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes2019

    • Author(s)
      Wakai T, Fissore RA
    • Journal Title

      Journal of Cell Science

      Volume: 132 Issue: 3 Pages: 1-1

    • DOI

      10.1242/jcs.225441

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K19202, KAKENHI-PROJECT-17K17905
  • [Journal Article] Ca2+ signaling and homeostasis in mammalian oocytes and eggs.2019

    • Author(s)
      Wakai T, Mehregan A, Fissore RA
    • Journal Title

      Cold spring harbor perspectives in biology

      Volume: 11 Issue: 12 Pages: a035162-a035162

    • DOI

      10.1101/cshperspect.a035162

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
  • [Journal Article] Removal of cumulus cells around 20 h after the start of <i>in vitro</i> maturation improves the meiotic competence of porcine oocytes via reduction in cAMP and cGMP levels2019

    • Author(s)
      Ferre-Pujol, P., Nguyen, X. K., Nagahara, T., Bui, T. T. M., Wakai, T., Funahashi, H.
    • Journal Title

      J. Reprod. Dev.

      Volume: 65 Issue: 2 Pages: 177-182

    • DOI

      10.1262/jrd.2018-130

    • NAID

      130007630932

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
  • [Journal Article] The autophagic inducer and inhibitor display different activities on the meiotic and developmental competencies of porcine oocytes derived from small and medium follicles2019

    • Author(s)
      Chiyuki KOHATA-ONO, Takuya WAKAI and Hiroaki FUNAHASHI
    • Journal Title

      J. Reprod. Dev.

      Volume: 65 Issue: 6 Pages: 527-532

    • DOI

      10.1262/jrd.2019-112

    • NAID

      130007768749

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
  • [Journal Article] XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†2018

    • Author(s)
      Sakashita Akihiko、Wakai Takuya、Kawabata Yukiko、Nishimura Chiaki、Sotomaru Yusuke、Alavattam Kris G、Namekawa Satoshi H、Kono Tomohiro
    • Journal Title

      Biology of Reproduction

      Volume: 100 Issue: 3 Pages: 697-710

    • DOI

      10.1093/biolre/ioy214

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17905, KAKENHI-PROJECT-18H02328
  • [Journal Article] Fertilization and the Signaling of Egg Activation2018

    • Author(s)
      Wakai Takuya、Mehregan Aujan、Fissore Rafael A.
    • Journal Title

      Reference Module in Biomedical Sciences

      Volume: 印刷中 Pages: 368-375

    • DOI

      10.1016/b978-0-12-801238-3.64656-1

    • ISBN
      9780128151457
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Journal Article] Presence of vascular endothelial growth factor during the first half of IVM improves the meiotic and developmental competence of porcine oocytes from small follicles.2017

    • Author(s)
      Bui TMT, Nguyen KX, Karata A, Ferre P, Tran MT, Wakai T, Funahashi H.
    • Journal Title

      Reproduction, Fertility and Development.

      Volume: 29 Issue: 10 Pages: 1902-1909

    • DOI

      10.1071/rd16321

    • NAID

      120006348281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19202, KAKENHI-PROJECT-17K17905
  • [Journal Article] Levels of cyclic-AMP and cyclic-GMP in porcine oocyte-cumulus complexes and cumulus-free oocytes derived from small and middle follicles during the first 24-hour period of in vitro maturation2017

    • Author(s)
      Okudaira Yuichi、Wakai Takuya、Funahashi Hiroaki
    • Journal Title

      Journal of Reproduction and Development

      Volume: 63 Pages: 191-197

    • NAID

      130007314630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] 加齢が卵母細胞および初期胚のミトコンドリア動態に及ぼす影響2022

    • Author(s)
      中戸沙也歌、月向はるな、小関元平、若井拓哉、舟橋弘晃
    • Organizer
      第72回関西畜産学会
    • Data Source
      KAKENHI-PROJECT-20K06627
  • [Presentation] 初期胚卵割時のミトコンドリア細胞間分配における細胞骨格の関与2022

    • Author(s)
      小関元平、中戸沙也歌、舟橋弘晃、若井拓哉
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K06627
  • [Presentation] ブタ卵母細胞におけるミトコンドリア染色方法の検討2020

    • Author(s)
      門田卓磨・若井拓也・舟橋弘晃
    • Organizer
      第70回関西畜産学会京都大会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] マウス卵母細胞におけるTrim-Away法を用いたリン酸化タンパク質の分解2019

    • Author(s)
      月向 はるな,野村 瑠莉,舟橋 弘晃,若井 拓哉
    • Organizer
      第112回日本繁殖生物学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] Trim-Away法を用いたマウス卵母細胞におけるDrp1の機能解析2019

    • Author(s)
      月向 はるな,野村 瑠莉,舟橋 弘晃,若井 拓哉.
    • Organizer
      第60回日本卵子学会
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] 着床前胚発生におけるミトコンドリア分裂因子Drp1の機能解析2019

    • Author(s)
      野村 瑠莉,月向 はるな,舟橋 弘晃,若井 拓哉
    • Organizer
      第60回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] ミトコンドリア分裂因子Drp1の阻害による着床前マウス胚の発生停止2019

    • Author(s)
      野村 瑠莉,月向 はるな,舟橋 弘晃,若井 拓哉
    • Organizer
      第112回日本繁殖生物学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] マウス卵母細胞におけるTrim-Away法を用いたリン酸化タンパク質の分解.2019

    • Author(s)
      月向 はるな,野村 瑠莉,舟橋 弘晃,若井 拓哉.
    • Organizer
      第112回日本繁殖生物学会
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] Trim-Away法を用いたマウス卵母細胞におけるDrp1の機能解析2019

    • Author(s)
      月向 はるな,野村 瑠莉,舟橋 弘晃,若井 拓哉
    • Organizer
      第60回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] 体外成熟時のブタ卵母細胞のオートファジー能は由来する小中卵胞で異なる2019

    • Author(s)
      小野千由貴、Mria Serrano Albal, Maria Bobis Rodriguez, 若井拓哉、舟橋弘晃
    • Organizer
      日本卵子学会学術集会第60回大会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] ミトコンドリア分裂因子Drp1の阻害による着床前マウス胚の発生停止.2019

    • Author(s)
      野村 瑠莉,月向 はるな,舟橋 弘晃,若井 拓哉.
    • Organizer
      第112回日本繁殖生物学会
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] トレハロースは小卵胞由来ブタ卵母細胞の体外成熟能を改善するがオートファジー能に影響しない2019

    • Author(s)
      小野千由貴、Mria Serrano Albal, Maria Bobis Rodriguez, Laura Cuenca、若井拓哉、舟橋弘晃
    • Organizer
      日本受精着床学会第37回総会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] 小中卵胞由来ブタ卵母細胞のオートファジー能とVEGFによる助長効果2018

    • Author(s)
      小野千由貴、若井拓哉、舟橋弘晃
    • Organizer
      第36回日本受精着床学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018

    • Author(s)
      野村瑠莉、月向はるな、舟橋弘晃、若井拓哉.
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018

    • Author(s)
      月向はるな、野村瑠莉、舟橋 弘晃、若井 拓哉
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-17K19202
  • [Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018

    • Author(s)
      野村瑠莉、月向はるな、舟橋弘晃、若井拓哉
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-17K19202
  • [Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018

    • Author(s)
      月向はるな、野村瑠莉、舟橋 弘晃、若井 拓哉.
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-17K17905
  • [Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018

    • Author(s)
      野村瑠莉、月向はるな、舟橋弘晃、若井拓哉
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018

    • Author(s)
      月向はるな、野村瑠莉、舟橋 弘晃、若井 拓哉
    • Organizer
      第18回日本ミトコンドリア学会
    • Data Source
      KAKENHI-PROJECT-18H02328
  • [Presentation] 卵母細胞における小胞体Ca2+ の制御とその役割2017

    • Author(s)
      若井拓哉
    • Organizer
      第35回日本受精着床学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19202
  • [Presentation] 卵母細胞における小胞体Ca2+ の制御とその役割2017

    • Author(s)
      若井拓哉
    • Organizer
      第35回日本受精着床学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K17905
  • 1.  FUNAHASHI Hiroaki (50284089)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  Ohtsuki Takashi (80321735)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  中塚 幹也 (40273990)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Motohashi Hideyuki (20554380)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Tsuji takehito (90314682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  高山 修 (80650879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  杉村 智史 (00728454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  松浦 宏治 (70443223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  森松 賢順 (70580934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  唄 花子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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