Wakai Takuya 若井拓哉

Researcher Number	60557768
Other IDs
Affiliation (Current)	2025: 岡山大学, 環境生命自然科学学域, 准教授
Affiliation (based on the past Project Information) *help	2023: 岡山大学, 環境生命自然科学学域, 准教授 2016 – 2023: 岡山大学, 環境生命科学研究科, 准教授 2021 – 2022: 岡山大学, 環境生命科学学域, 准教授
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 44010:Cell biology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 90110:Biomedical engineering-related / Basic Section 42040:Laboratory animal science-related / Basic Section 42010:Animal production science-related / Biomolecular chemistry and related fields / Obstetrics and gynecology
Keywords	Principal Investigator マウス / ミトコンドリア / ライブセルイメージング / 加齢 / カルシウムシグナリング / 小胞体 / オルガネラ / 卵母細胞 / 染色体 / 不妊 … More / 微小核 / 酸化ストレス / 活性酸素 / 染色体異常 / 初期胚 / カルシウム / カルシウムシグナル / 動物 / 老化 / アクチンフィラメント / 減数分裂 / 卵成熟 / 受精 … More Except Principal Investigator 細胞内カルシウム濃度 / 代謝 / ATP / 精子運動性 / マウス / 細胞外マトリックス / 突然変異 / 不妊 / ADAMTSL2 / ミュータントマウス / 下垂体 / 性成熟 / 卵巣 / ovary / Adamtsl2 / マイトファジー / ミトコンドリアDNA / オートファジー / 時空間的制御 / ミトコンドリア / 初期発生能 / 卵母細胞 / 発生 / 光制御 / 翻訳 / ケージドアミノアシルtRNA / 応用動物 / 細胞・組織 / 再生医学 / 発生・分化 / 移植・再生医療 / 卵巣凍結保存 Less

着床前胚発生における微小核形成へのミトコンドリア機能の関与Principal Investigator
- Principal Investigator
  
  若井拓哉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Okayama University
Studies on motility control mechanism of mammalian sprematozoa using ATP imaging
- Principal Investigator
  
  松浦宏治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Okayama University of Science
Regulation of ovarian function by Adamtsl2, a novel causative gene isolated from infertile mutant mice
- Principal Investigator
  
  Tsuji takehito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Okayama University
Physiological analysis of the endoplasmic reticulum-mitochondria contact sites in oocytesPrincipal Investigator
- Principal Investigator
  
  Wakai Takuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Okayama University
Creation of mammalian oocytes with high fertility by spatiotemporal regulation of the function of mitochondria
- Principal Investigator
  
  FUNAHASHI Hiroaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Okayama University
Photo-triggered translation using caged aminoacyl-tRNA in early embryos
- Principal Investigator
  
  Ohtsuki Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomolecular chemistry and related fields
- Research Institution
  Okayama University
Organelle dynamics during meiotic maturation of mouse oocytesPrincipal Investigator
- Principal Investigator
  
  Wakai Takuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Okayama University
Cryopreservation of ovarian tissue
- Principal Investigator
  
  Motohashi Hideyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical University
  Okayama University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] Encyclopedia of Reproduction (Second Edition)2018
- Author(s)
  Wakai T., Mehregan A., Fissore R.A.（部分執筆）
- Total Pages
  3868
- Publisher
  Elsevier
- ISBN
  9780128118993
- Data Source
  KAKENHI-PROJECT-17K19202
[Book] Encyclopedia of Reproduction (Second Edition)2018
- Author(s)
  Wakai T, Mehregan A, Fissore RA.
- Total Pages
  3868
- Publisher
  Academic Press
- ISBN
  9780128118993
- Data Source
  KAKENHI-PROJECT-17K17905
[Journal Article] Cell-cycle dependent GATA2 subcellular localization in mouse 2-cell embryos2021
- Author(s)
  Komatsu Masaya, Tsukahara Hayato, Bai Hanako, Takahashi Masashi, Wakai Takuya, Kawahara Manabu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 584 Pages: 1-6
- DOI
  10.1016/j.bbrc.2021.10.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15644, KAKENHI-PROJECT-21H02336, KAKENHI-PROJECT-20K06627
[Journal Article] Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes2019
- Author(s)
  Wakai T, Fissore RA
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Issue: 3 Pages: 1-1
- DOI
  10.1242/jcs.225441
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K19202, KAKENHI-PROJECT-17K17905
[Journal Article] Ca2+ signaling and homeostasis in mammalian oocytes and eggs.2019
- Author(s)
  Wakai T, Mehregan A, Fissore RA
- Journal Title
  
  Cold spring harbor perspectives in biology
  
  Volume: 11 Issue: 12 Pages: a035162-a035162
- DOI
  10.1101/cshperspect.a035162
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
[Journal Article] Removal of cumulus cells around 20 h after the start of <i>in vitro</i> maturation improves the meiotic competence of porcine oocytes via reduction in cAMP and cGMP levels2019
- Author(s)
  Ferre-Pujol, P., Nguyen, X. K., Nagahara, T., Bui, T. T. M., Wakai, T., Funahashi, H.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 2 Pages: 177-182
- DOI
  10.1262/jrd.2018-130
- NAID
  130007630932
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
[Journal Article] The autophagic inducer and inhibitor display different activities on the meiotic and developmental competencies of porcine oocytes derived from small and medium follicles2019
- Author(s)
  Chiyuki KOHATA-ONO, Takuya WAKAI and Hiroaki FUNAHASHI
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 6 Pages: 527-532
- DOI
  10.1262/jrd.2019-112
- NAID
  130007768749
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02328, KAKENHI-PROJECT-17K17905
[Journal Article] XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†2018
- Author(s)
  Sakashita Akihiko、Wakai Takuya、Kawabata Yukiko、Nishimura Chiaki、Sotomaru Yusuke、Alavattam Kris G、Namekawa Satoshi H、Kono Tomohiro
- Journal Title
  
  Biology of Reproduction
  
  Volume: 100 Issue: 3 Pages: 697-710
- DOI
  10.1093/biolre/ioy214
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17905, KAKENHI-PROJECT-18H02328
[Journal Article] Fertilization and the Signaling of Egg Activation2018
- Author(s)
  Wakai Takuya、Mehregan Aujan、Fissore Rafael A.
- Journal Title
  
  Reference Module in Biomedical Sciences
  
  Volume: 印刷中 Pages: 368-375
- DOI
  10.1016/b978-0-12-801238-3.64656-1
- ISBN
  9780128151457
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17905
[Journal Article] Presence of vascular endothelial growth factor during the first half of IVM improves the meiotic and developmental competence of porcine oocytes from small follicles.2017
- Author(s)
  Bui TMT, Nguyen KX, Karata A, Ferre P, Tran MT, Wakai T, Funahashi H.
- Journal Title
  
  Reproduction, Fertility and Development.
  
  Volume: 29 Issue: 10 Pages: 1902-1909
- DOI
  10.1071/rd16321
- NAID
  120006348281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19202, KAKENHI-PROJECT-17K17905
[Journal Article] Levels of cyclic-AMP and cyclic-GMP in porcine oocyte-cumulus complexes and cumulus-free oocytes derived from small and middle follicles during the first 24-hour period of in vitro maturation2017
- Author(s)
  Okudaira Yuichi、Wakai Takuya、Funahashi Hiroaki
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 63 Pages: 191-197
- NAID
  130007314630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] 加齢が卵母細胞および初期胚のミトコンドリア動態に及ぼす影響2022
- Author(s)
  中戸沙也歌、月向はるな、小関元平、若井拓哉、舟橋弘晃
- Organizer
  第72回関西畜産学会
- Data Source
  KAKENHI-PROJECT-20K06627
[Presentation] 初期胚卵割時のミトコンドリア細胞間分配における細胞骨格の関与2022
- Author(s)
  小関元平、中戸沙也歌、舟橋弘晃、若井拓哉
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06627
[Presentation] ブタ卵母細胞におけるミトコンドリア染色方法の検討2020
- Author(s)
  門田卓磨・若井拓也・舟橋弘晃
- Organizer
  第70回関西畜産学会京都大会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] マウス卵母細胞におけるTrim-Away法を用いたリン酸化タンパク質の分解2019
- Author(s)
  月向はるな，野村瑠莉，舟橋弘晃，若井拓哉
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] Trim-Away法を用いたマウス卵母細胞におけるDrp1の機能解析2019
- Author(s)
  月向はるな，野村瑠莉，舟橋弘晃，若井拓哉．
- Organizer
  第60回日本卵子学会
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] 着床前胚発生におけるミトコンドリア分裂因子Drp1の機能解析2019
- Author(s)
  野村瑠莉，月向はるな，舟橋弘晃，若井拓哉
- Organizer
  第60回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] ミトコンドリア分裂因子Drp1の阻害による着床前マウス胚の発生停止2019
- Author(s)
  野村瑠莉，月向はるな，舟橋弘晃，若井拓哉
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] マウス卵母細胞におけるTrim-Away法を用いたリン酸化タンパク質の分解．2019
- Author(s)
  月向はるな，野村瑠莉，舟橋弘晃，若井拓哉．
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] Trim-Away法を用いたマウス卵母細胞におけるDrp1の機能解析2019
- Author(s)
  月向はるな，野村瑠莉，舟橋弘晃，若井拓哉
- Organizer
  第60回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] 体外成熟時のブタ卵母細胞のオートファジー能は由来する小中卵胞で異なる2019
- Author(s)
  小野千由貴、Mria Serrano Albal, Maria Bobis Rodriguez, 若井拓哉、舟橋弘晃
- Organizer
  日本卵子学会学術集会第60回大会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] ミトコンドリア分裂因子Drp1の阻害による着床前マウス胚の発生停止．2019
- Author(s)
  野村瑠莉，月向はるな，舟橋弘晃，若井拓哉．
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] トレハロースは小卵胞由来ブタ卵母細胞の体外成熟能を改善するがオートファジー能に影響しない2019
- Author(s)
  小野千由貴、Mria Serrano Albal, Maria Bobis Rodriguez, Laura Cuenca、若井拓哉、舟橋弘晃
- Organizer
  日本受精着床学会第37回総会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] 小中卵胞由来ブタ卵母細胞のオートファジー能とVEGFによる助長効果2018
- Author(s)
  小野千由貴、若井拓哉、舟橋弘晃
- Organizer
  第36回日本受精着床学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018
- Author(s)
  野村瑠莉、月向はるな、舟橋弘晃、若井拓哉．
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018
- Author(s)
  月向はるな、野村瑠莉、舟橋　弘晃、若井　拓哉
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-17K19202
[Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018
- Author(s)
  野村瑠莉、月向はるな、舟橋弘晃、若井拓哉
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-17K19202
[Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018
- Author(s)
  月向はるな、野村瑠莉、舟橋　弘晃、若井　拓哉．
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-17K17905
[Presentation] 着床前マウス胚におけるミトコンドリア分裂因子Drp1の役割2018
- Author(s)
  野村瑠莉、月向はるな、舟橋弘晃、若井拓哉
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] マウス卵母細胞におけるTrim-away法を用いたDrp1タンパク質の分解2018
- Author(s)
  月向はるな、野村瑠莉、舟橋　弘晃、若井　拓哉
- Organizer
  第18回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-18H02328
[Presentation] 卵母細胞における小胞体Ca2+ の制御とその役割2017
- Author(s)
  若井拓哉
- Organizer
  第35回日本受精着床学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19202
[Presentation] 卵母細胞における小胞体Ca2+ の制御とその役割2017
- Author(s)
  若井拓哉
- Organizer
  第35回日本受精着床学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K17905

1. FUNAHASHI Hiroaki (50284089)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. Ohtsuki Takashi (80321735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 中塚幹也 (40273990)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Motohashi Hideyuki (20554380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Tsuji takehito (90314682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高山修 (80650879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 杉村智史 (00728454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松浦宏治 (70443223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森松賢順 (70580934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 唄花子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wakai Takuya 若井 拓哉

Research Projects

Research Products

Co-Researchers

着床前胚発生における微小核形成へのミトコンドリア機能の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on motility control mechanism of mammalian sprematozoa using ATP imaging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of ovarian function by Adamtsl2, a novel causative gene isolated from infertile mutant mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological analysis of the endoplasmic reticulum-mitochondria contact sites in oocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of mammalian oocytes with high fertility by spatiotemporal regulation of the function of mitochondria

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Photo-triggered translation using caged aminoacyl-tRNA in early embryos

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Organelle dynamics during meiotic maturation of mouse oocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cryopreservation of ovarian tissue

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Encyclopedia of Reproduction (Second Edition)2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] Encyclopedia of Reproduction (Second Edition)2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Cell-cycle dependent GATA2 subcellular localization in mouse 2-cell embryos2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Constitutive IP3R1-mediated Ca2+ release reduces Ca2+ store content and stimulates mitochondrial metabolism in mouse GV oocytes2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ca2+ signaling and homeostasis in mammalian oocytes and eggs.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Removal of cumulus cells around 20 h after the start of <i>in vitro</i> maturation improves the meiotic competence of porcine oocytes via reduction in cAMP and cGMP levels2019

Wakai Takuya 若井拓哉