Tanaka Shingo 田中信悟

… Alternative Names

TANAKA Shingo 田中信悟

田中信悟タナカシンゴ

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Researcher Number	60561024
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 札幌医科大学, 医学部, 助教 2012 – 2014: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator 酸化的DNA傷害修復酵素 / 肝細胞癌 / モデルマウス / MUTYH / 酸化ストレス / 鉄過剰 / NASH / 抗腫瘍薬スクリーニング / in vitroスクリーニング / 分子標的薬 … More / オルガノイド / マウス / 鉄過剰食 / 抗酸化剤 / マイクロRNA核酸医薬 / 抗酸化療法 / マウスモデル / NAFLD / 鉄 / 8-OHdG / DMT1 / IRP1 / IRP 1 … More Except Principal Investigator 固形癌 / CIML NK細胞 / 膵臓癌 / NK細胞 / CAR / CIML / CAR-NK / 薬物搬送 / 治療 / 相乗効果 / ヒストン脱アセチル化酵素 / 化学療法 / 肝細胞癌 / 遺伝子修復酵素 / 慢性肝炎 / 肝癌 / 酸化的DNA損傷修復遺伝子 / 肝癌診断 / 酸化的DNA損傷 / 肝癌予防 / 肝発癌危険因子 Less

Novel strategies for the treatment of solid tumors with CAR and CIML NK cells
- Principal Investigator
  
  Miyanishi Koji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
酸化的DNA傷害修復酵素欠損マウス由来肝腫瘍オルガノイドを用いた新規治療法の探索Principal Investigator
- Principal Investigator
  
  田中信悟
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Elucidation of NASH hepatocarcinogenesis mechanism and therapeutic application using oxidative DNA damage repair enzyme-deficient micePrincipal Investigator
- Principal Investigator
  
  Tanaka Shingo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Development of novel treatment for liver cancer with class-selective HDAC inhibitors
- Principal Investigator
  
  Miyanishi Koji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Elucidation of induction mechanism of iron oxidative stress in NASH and application to treatmentPrincipal Investigator
- Principal Investigator
  
  TANAKA Shingo
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Analysis of relation between oxidative DNA repair genes,MUTYH and hepatocarcinogenesis
- Principal Investigator
  
  MIYANISHI Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University

All 2024 2023 2022 2021 2020 2019 2013 2012

All Journal Article Presentation

[Journal Article] Efficient implementation of hepatitis B surface antigen confirmatory neutralization tests2024
- Author(s)
  Yonezawa Hitoshi、Tanaka Shingo、Tanaka Makito、Kobayashi Ryo、Takahashi Satoshi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 30 Issue: 1 Pages: 29-33
- DOI
  10.1016/j.jiac.2023.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08011
[Journal Article] Pulmonary Metastasectomy after Radiofrequency Ablation of Hepatocellular Carcinoma2024
- Author(s)
  Osuga Takahiro、Tanaka Shingo、Kubo Tomohiro、Hamaguchi Kota、Ito Ryo、Sakurada Akira、Ishikawa Keidai、Miyanishi Koji
- Journal Title
  
  Case Reports in Oncology
  
  Volume: 17 Issue: 1 Pages: 407-416
- DOI
  10.1159/000536498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08011
[Journal Article] 脂肪性肝疾患における血液学的バイオマーカーおよびスコアリングシステムの現状2023
- Author(s)
  田中信悟, 田中真輝人, 高橋聡
- Journal Title
  
  医療検査と自動化
  
  Volume: 48 Pages: 477-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08011
[Journal Article] Occurrence of Autoimmune Encephalitis in a Patient with Hepatocellular Carcinoma after Atezolizumab and Bevacizumab Combination Therapy: A Case Study2023
- Author(s)
  Osuga Takahiro、Miyanishi Koji、Ito Ryo、Tanaka Shingo、Kubo Tomohiro、Hamaguchi Kota、Ohnuma Hiroyuki、Murase Kazuyuki、Takada Kohichi、Yamamoto Morihiro、Manabe Tatsuo、Hisahara Shin、Kato Junji
- Journal Title
  
  Kanzo
  
  Volume: 64 Issue: 11 Pages: 559-566
- DOI
  10.2957/kanzo.64.559
- ISSN
  0451-4203, 1881-3593
- Year and Date
  2023-11-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08011, KAKENHI-PROJECT-22K07541
[Journal Article] The coefficient of determination is affected by the attenuation coefficient in attenuation imaging2023
- Author(s)
  Shingo Tanaka, Noboru Ohba, Kiyoshi Abe, Yuka Tamoto, Kenji Yasui, Chihiro Kobayashi, Nagomi Saito, Koji Miyanishi, Satoshi Takahashi, Junji Kato
- Journal Title
  
  Laboratory Medicine International
  
  Volume: 2 Issue: 3 Pages: 42-49
- DOI
  10.51041/lmi.2.3_42
- ISSN
  2436-8660
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08011
[Journal Article] Synergistic antitumor effect of histone deacetylase class IIa inhibitor with lenvatinib in hepatocellular carcinoma2023
- Author(s)
  Ito Ryo、Miyanishi Koji、Kubo Tomohiro、Hamaguchi Kota、Osuga Takahiro、Tanaka Shingo、Ohnuma Hiroyuki、Murase Kazuyuki、Takada Kohichi、Nagayama Minoru、Kimura Yasutoshi、Mizuguchi Toru、Takemasa Ichiro、Kato Junji
- Journal Title
  
  Hepatology International
  
  Volume: - Issue: 3 Pages: 735-744
- DOI
  10.1007/s12072-023-10484-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08011, KAKENHI-PROJECT-22K08080
[Journal Article] Association between hepatic oxidative stress related factors and activation of Wnt/β-catenin signaling in NAFLD-induced hepatocellular carcinoma.2022
- Author(s)
  Hamaguchi K, Miyanishi K, Osuga T, Tanaka S, Ito R, Sakamoto H, Kubo T, Ohnuma H, Murase K, Takada K, Nagayama M, Kimura Y, Mizuguchi T, Takemasa I, Kato J.
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 9 Pages: 2066-2066
- DOI
  10.3390/cancers14092066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10404, KAKENHI-PROJECT-21K08011, KAKENHI-PROJECT-22K08080
[Journal Article] Effect of albumin measurement methods on the albumin?bilirubin grade2022
- Author(s)
  Tanaka Makito、Tanaka Shingo、Suzuki Ema、Kobayashi Ryo、Takahashi Satoshi
- Journal Title
  
  Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
  
  Volume: 60 Issue: 2 Pages: 100-108
- DOI
  10.1177/00045632221143685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08011
[Journal Article] MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model2021
- Author(s)
  Sakamoto Hiroki、Miyanishi Koji、Tanaka Shingo、Ito Ryo、Hamaguchi Kota、Sakurada Akira、Sato Masanori、Kubo Tomohiro、Osuga Takahiro、Murase Kazuyuki、Takada Kohichi、Nakabeppu Yusaku、Kobune Masayoshi、Kato Junji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-83138-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08397, KAKENHI-PROJECT-19K08871, KAKENHI-PROJECT-19K17405, KAKENHI-PROJECT-21K08011
[Journal Article] The role of iron in hepatic inflammation and hepatocellular carcinoma2019
- Author(s)
  Miyanishi K, Tanaka S, Sakamoto H, Kato J
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 133 Pages: 200-205
- DOI
  10.1016/j.freeradbiomed.2018.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17405, KAKENHI-PROJECT-17H03599
[Journal Article] Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.2013
- Author(s)
  Tanaka S, Miyanishi K, Kobune M, Kawano Y, Hoki T, Kubo T, Hayashi T, Sato T, Sato Y, Takimoto R, Kato J.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 48(11) Issue: 11 Pages: 1249-58
- DOI
  10.1007/s00535-012-0739-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590985
[Presentation] NASHからの肝発癌における酸化的DNA傷害修復酵素の関与2020
- Author(s)
  坂本拡基、宮西浩嗣、伊藤亮、濱口孝太、久保智洋、大須賀崇裕、田中信悟、大沼啓之、村瀬和幸、高田弘一、加藤淳二
- Organizer
  第106回消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K17405
[Presentation] NASHモデルマウスを用いた，DNA傷害修復酵素MUTYHの肝発癌への関与の検討2019
- Author(s)
  坂本拡基、宮西浩嗣、田中信悟、大須賀崇裕、村瀬和幸、高田弘一、加藤淳二
- Organizer
  第55回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K17405
[Presentation] 肝発癌における８－OHｄGの関与について2013
- Author(s)
  宮西浩嗣、田中信悟、小船雅義、加藤淳二
- Organizer
  日本鉄バイオサイエンス学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590985
[Presentation] NASHにおける鉄代謝異常の機序と肝発癌への関与の検討2012
- Author(s)
  宮西浩嗣，田中慎悟，加藤淳二
- Organizer
  第23回日本微量元素学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590985

1. MIYANISHI Koji (60372819)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. JUNJI Kato (20244345)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
3. 田中信悟 (60564024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 菊地尚平 (80515792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 久保智洋 (00634669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 大須賀崇裕 (40619714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 濱口孝太 (50866613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAMOTO hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAGAYAMA Minoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 水口徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 高田弘一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Shingo 田中 信悟

TANAKA Shingo 田中 信悟

田中 信悟 タナカ シンゴ

Research Projects

Research Products

Co-Researchers

Novel strategies for the treatment of solid tumors with CAR and CIML NK cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

酸化的DNA傷害修復酵素欠損マウス由来肝腫瘍オルガノイドを用いた新規治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of NASH hepatocarcinogenesis mechanism and therapeutic application using oxidative DNA damage repair enzyme-deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel treatment for liver cancer with class-selective HDAC inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of induction mechanism of iron oxidative stress in NASH and application to treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of relation between oxidative DNA repair genes,MUTYH and hepatocarcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Efficient implementation of hepatitis B surface antigen confirmatory neutralization tests2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pulmonary Metastasectomy after Radiofrequency Ablation of Hepatocellular Carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 脂肪性肝疾患における血液学的バイオマーカーおよびスコアリングシステムの現状2023

Author(s)

Journal Title

Data Source

[Journal Article] Occurrence of Autoimmune Encephalitis in a Patient with Hepatocellular Carcinoma after Atezolizumab and Bevacizumab Combination Therapy: A Case Study2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] The coefficient of determination is affected by the attenuation coefficient in attenuation imaging2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Synergistic antitumor effect of histone deacetylase class IIa inhibitor with lenvatinib in hepatocellular carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between hepatic oxidative stress related factors and activation of Wnt/β-catenin signaling in NAFLD-induced hepatocellular carcinoma.2022

Author(s)

Journal Title

DOI

Tanaka Shingo 田中信悟

TANAKA Shingo 田中信悟

田中信悟タナカシンゴ