Miura Yoko 三浦陽子

Researcher Number	60563517
Other IDs
Affiliation (Current)	2026: 名古屋市立大学, 医薬学総合研究院(医学), 研究員
Affiliation (based on the past Project Information) *help	2019 – 2024: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2017 – 2018: 名古屋市立大学, 大学院医学研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Respiratory organ internal medicine Except Principal Investigator Collagenous pathology/Allergology
Keywords	Principal Investigator 関節リウマチ / パンヌス / シングルセル解析 / 新生血管 / single cell RNAseq / 新生血管形成 / 動物モデル / 軟骨内骨化 / 滑膜線維芽細胞 / 骨性強直 … More / 肺線維症 / NSIP / UIP / モデルマウス / 間質性肺炎 / 線維化 / 間質性肺炎モデル … More Except Principal Investigator 間質性肺炎 / PAD4 / 関節リウマチ Less

Characterization of neovascular cells in pannus leads to novel therapeutic strategies for rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  三浦陽子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagoya City University
Identification of specific synovial fibroblast leading to aberrant bone formation and analysis of synoviocyte differentiationPrincipal Investigator
- Principal Investigator
  
  Miura Yoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagoya City University
Study of suppressing effect by PAD4 catalytic cleft blocking antibody to rheumatoid arthritis and interstitial pneumonitis
- Principal Investigator
  
  Kanazawa Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Nagoya City University
Study of suppressing effect to interstitial pneumonitis by nintedanib in a novel mouse modelPrincipal Investigator
- Principal Investigator
  
  Miura Yoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya City University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] CTLA-4-Ig internalizes CD80 in fibroblast-like synoviocytes from chronic inflammatory arthritis mouse model2022
- Author(s)
  Miura Yoko、Isogai Shyuntaro、Maeda Shinji、Kanazawa Satoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 16363-16363
- DOI
  10.1038/s41598-022-20694-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17447
[Journal Article] Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model2021
- Author(s)
  Miura Yoko、Ohkubo Hirotsugu、Niimi Akio、Kanazawa Satoshi
- Journal Title
  
  ERJ Open Research
  
  Volume: 7 Issue: 4 Pages: 00345-00345
- DOI
  10.1183/23120541.00345-2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17447
[Journal Article] Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia2021
- Author(s)
  Miura Yoko、Lam Maggie、Bourke Jane E、Kanazawa Satoshi
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 1 Pages: e202101059-e202101059
- DOI
  10.26508/lsa.202101059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17447
[Journal Article] Osteochondrogenesis derived from synovial fibroblasts in inflammatory arthritis model2020
- Author(s)
  Yoko Miura, Satoshi Kanazawa
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 40 Pages: 7-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17447
[Journal Article] A subpopulation of synovial fibroblasts in a mouse model of chronic inflammatory rheumatoid arthritis toward osteochondrogenic lineage2019
- Author(s)
  Yoko Miura, Shusuke Ota, Matija Peterlin, Grete McDevitt, Satoshi Kanazawa
- Journal Title
  
  JBMR plus
  
  Volume: 印刷中 Issue: 6
- DOI
  10.1002/jbm4.10132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16055
[Journal Article] Effect of H2 treatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease2019
- Author(s)
  Terasaki Y.,Terasaki M., Kanazawa S.,Kokuho M., Urushiyama H., Kajimoto Y., Kunugi S., Maruyama M., Akimoto T., Miura Y., Igarashi T.,Ohsawa I., Shimizu A
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 23 Issue: 10 Pages: 7043-7053
- DOI
  10.1111/jcmm.14603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] パンヌス由来CD146mid細胞は肥大化軟骨細胞を経由し骨分化に向かい骨性強直の原因となる2024
- Author(s)
  三浦陽子　金澤智
- Organizer
  第68回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-23K07879
[Presentation] 特発性肺線維症マウスモデル由来のPCLS肺はブレオマイシン処理によりgH2AXが核周囲に発現し、より強い老化状態になる2023
- Author(s)
  三浦陽子　高田晶帆　金澤智
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K07879
[Presentation] induced-UIPマウスモデル由来PCLSは線維化因子添加による線維産生能が高い2023
- Author(s)
  三浦陽子　金澤智
- Organizer
  第63回　日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07879
[Presentation] パンヌスにおける特定のCD146陽性線維芽細胞は骨分化に向かう集団である2022
- Author(s)
  三浦陽子　金澤智
- Organizer
  第43回日本炎症・再生学会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] アバタセプトはCD80を内在化させ、T細胞の活性化抑制および抗体産生能の抑制に関与する2022
- Author(s)
  三浦陽子　磯谷俊太郎　前田伸治　金澤智
- Organizer
  第66回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] iUIPマウスモデル由来PCLS ex vivo培養を用いた線維化状態の比較検討2021
- Author(s)
  三浦陽子　金澤智
- Organizer
  第61回　日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] アバタセプトはリンパ節におけるB細胞を減少させ、抗体産生能を抑制する2021
- Author(s)
  三浦陽子　磯谷俊太郎　前田伸治　金澤智
- Organizer
  第42回日本炎症・再生学会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] CTLA-4 Igはリンパ節におけるB細胞を減少させ、抗体産生能を抑制する2021
- Author(s)
  三浦陽子磯谷俊太郎前田伸治金澤智
- Organizer
  第44回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] iUIPマウスモデルにおけるニンテダニブ投与の特発性肺線維症様病態に対する抑制効果検討2020
- Author(s)
  三浦陽子　大久保仁嗣　新実彰男　金澤智
- Organizer
  第60回　日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] ニンテダニブは抗炎症作用および抗線維化作用を有し、関節リウマチ関連肺疾患モデル (D1CC×D1BCマウス) でみられる線維化を抑制する2020
- Author(s)
  三浦陽子　金澤智
- Organizer
  第41回日本炎症・再生学会
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] Nintedanib attenuates interstitial pneumonia in a mouse model with UIP features2020
- Author(s)
  Yoko Miura, Hirotsugu Ohkubo, Akio Niimi, and Satoshi Kanazawa.
- Organizer
  ATS conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17447
[Presentation] 二峰性線維化状態を示す間質性肺炎モデルマウス (induced-UIP model) における組織学的な解析2019
- Author(s)
  金澤智　三浦陽子
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] Runx2+, Sox9+陽性滑膜線維芽細胞は肥大化軟骨細胞へ分化し骨性強直の原因となる2019
- Author(s)
  三浦陽子　金澤智
- Organizer
  第61回日本リウマチ学会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] Nintedanib attenuates histopathology of interstitial pneumonia in a transgenic mouse model of arthritis.2018
- Author(s)
  Yoko Miura, Satoshi Kanazawa, Hirotsugu Ohkubo, Akio Niimi
- Organizer
  ATS conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] 慢性間質性肺炎を呈する関節リウマチモデルにおけるニンテダニブの治療効果の検討2018
- Author(s)
  三浦陽子　金澤智　大久保仁嗣　新実彰男
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] 間質性肺炎モデルマウスにおける急性期、慢性期炎症における線維芽細胞の解析およびDNA障害関連マーカーの検討2018
- Author(s)
  三浦陽子　金澤智
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] 急性期における自己免疫、慢性期における増殖性上皮細胞以上を特徴とする2相性間質性肺2018
- Author(s)
  金澤智　三浦陽子
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] The fate of synovial fibroblasts in a mouse model of chronic inflammatory rheumatoid arthritis2018
- Author(s)
  Yoko Miura, Satoshi Kanazawa
- Organizer
  JCR international school 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] Ectopic expression of B7.1 (CD80) in chondrocytes leads to chronic inflammatory arthritis in mice2018
- Author(s)
  Yoko Miura, Satoshi Kanazawa
- Organizer
  第19回武田科学振興財団生命科学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] 慢性関節炎炎症時における滑膜線維芽細胞は全肥大化軟骨細胞の表現型を有する2017
- Author(s)
  三浦陽子　金澤智
- Organizer
  JCR第4回ベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] A novel interstitial pneumonitis mouse model, D1CC x D1BC mouse shows chronic inflammation with sevre fibrosis in lung2017
- Author(s)
  Satoshi Kanazawa, Yoko Miura
- Organizer
  Keystone symposia
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] 慢性関節炎炎症時における滑膜線維芽細胞は全肥大化軟骨細胞の表現型を有し骨分化する2017
- Author(s)
  三浦陽子　金澤智
- Organizer
  第68回名古屋市立大学医学会総会
- Data Source
  KAKENHI-PROJECT-17K16055
[Presentation] Synovial fibroblasts has a potential ability as pre-hypertrophic chondrocytes in chronic inflammation of rheumatoid arthritis model, D1BC mouse2017
- Author(s)
  Yoko Miura, Satoshi Kanazawa
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K16055

1. Kanazawa Satoshi (90347401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results

Miura Yoko 三浦 陽子

Research Projects

Research Products

Co-Researchers

Characterization of neovascular cells in pannus leads to novel therapeutic strategies for rheumatoid arthritis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of specific synovial fibroblast leading to aberrant bone formation and analysis of synoviocyte differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of suppressing effect by PAD4 catalytic cleft blocking antibody to rheumatoid arthritis and interstitial pneumonitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of suppressing effect to interstitial pneumonitis by nintedanib in a novel mouse modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CTLA-4-Ig internalizes CD80 in fibroblast-like synoviocytes from chronic inflammatory arthritis mouse model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteochondrogenesis derived from synovial fibroblasts in inflammatory arthritis model2020

Author(s)

Journal Title

Data Source

[Journal Article] A subpopulation of synovial fibroblasts in a mouse model of chronic inflammatory rheumatoid arthritis toward osteochondrogenic lineage2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of H2 treatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] パンヌス由来CD146mid細胞は肥大化軟骨細胞を経由し骨分化に向かい骨性強直の原因となる2024

Author(s)

Organizer

Data Source

[Presentation] 特発性肺線維症マウスモデル由来のPCLS肺はブレオマイシン処理によりgH2AXが核周囲に発現し、より強い老化状態になる2023

Author(s)

Organizer

Data Source

[Presentation] induced-UIPマウスモデル由来PCLSは線維化因子添加による線維産生能が高い2023

Author(s)

Organizer

Data Source

[Presentation] パンヌスにおける特定のCD146陽性線維芽細胞は骨分化に向かう集団である2022

Author(s)

Organizer

Data Source

[Presentation] アバタセプトはCD80を内在化させ、T細胞の活性化抑制および抗体産生能の抑制に関与する2022

Author(s)

Organizer

Data Source

[Presentation] iUIPマウスモデル由来PCLS ex vivo培養を用いた線維化状態の比較検討2021

Author(s)

Organizer

Miura Yoko 三浦陽子