Kanasaki Keizo 金崎啓造

… Alternative Names

KANASAKI Keizo 金崎啓造

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Researcher Number	60589919
Other IDs	https://orcid.org/0000-0002-9563-502X
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 島根大学, 学術研究院医学・看護学系, 教授 2014 – 2018: 金沢医科大学, 医学部, 准教授 2011 – 2014: 金沢医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Pathological medical chemistry Except Principal Investigator Kidney internal medicine / Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related / Eating habits / Applied pharmacology / Medical pharmacy
Keywords	Principal Investigator COMT / 妊娠高血圧腎症 / 腎臓 / 高血圧 / エストロゲン代謝 / metabolic syndrome / 2-methoxyestradiol / メタボリックシンドローム / フィブロネクチン / スプライスゾーム … More / DKD / 糖尿病性腎症 / 線維化 / 抗老化 / サルコペニア / H2O2 / IL-18 / lactate / BAIBA / マグネシウム / サイアザイド / DOHaD / エストロゲン / 塩分感受性高血圧 / カテコール代謝 / 耐糖能異常 / 生活習慣病 / insulin / PPAR-g / アンジオテンシン / インスリン / 妊娠糖尿病 / メタボリックシンドロームボリックシンドローム / 脂肪肝 / 糖尿病 … More Except Principal Investigator 糖尿病 / オートファジー / 腎線維化 / IL-6 / 内皮細胞 / 内皮・間葉転化 / 線維化 / 糖尿病性腎症 / AcSDKP / COMT / magnesium / S-adenosylmethionine / homocysteine / S-adenosylhomocysteine / 血管内皮細胞 / 上皮間葉転化 / 内皮間葉転化 / 内皮 / 膵島 / 心線維化 / 内皮・間葉化 / 内皮間葉化 / 心臓 / 腎臓 / 高脂肪食負荷 / メトフォルミン / マイクロRNA / 糖尿病腎症 / miRNA / microRNA / SIRT1 / mTOR / 代謝 / 骨格筋 / ケト原性アミノ酸 / ポドサイト / 腎障害 / 代謝異常 / メチオニン / たんぱく質 / ケイ原性アミノ酸 / たんぱく質制限 / カロリー制限 / EndMT / 2-methoxyestradiol / インスリン / パーキンソン病 / インスリン抵抗性 Less

スプライソソーム機能異常に着目した糖尿病関連腎臓病に対する治療戦略の開発Principal Investigator
- Principal Investigator
  
  金崎啓造
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shimane University
微量栄養素欠乏および補充が糖尿病性腎症の進展とサルコペニアに与える影響の解明
- Principal Investigator
  
  太田美和
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Shimane University
Potency of enhancer compounds in the filed of renal and cardiovascular diseases.
- Principal Investigator
  
  飯島洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nihon University
サルコペニア合併糖尿病性腎臓病における負のスパイラルを標的とした治療戦略の開発Principal Investigator
- Principal Investigator
  
  金崎啓造
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shimane University
Interaction between genetic COMT deficiency and Mg defects induced diseases: mechanisms and therapeutic strategyPrincipal Investigator
- Principal Investigator
  
  KANASAKI Keizo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shimane University
Endothelial autophagy deficiency induces interleukin 6-dependent endothelial mesenchymal transition and organ fibrosis
- Principal Investigator
  
  KOYA Daisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa Medical University
The investigation of the molecular mechanisms in COMT-deficiency-induced health problemsPrincipal Investigator
- Principal Investigator
  
  KANASAKI Keizo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa Medical University
Alteration in nutrient sensing and metabolic diseases
- Principal Investigator
  
  KOYA Daisuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
New therapeutic strategy for diabetic nephropathy via autophagy regulation
- Principal Investigator
  
  KOYA Daisuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kanazawa Medical University
Understanding of the metabolic abnormalities induced by COMT inhibitor administration
- Principal Investigator
  
  KIM Hyoh
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Shiga University of Medical Science
Development of control means of renal fibrosis focused on endogenous anti-fibrotic molecule
- Principal Investigator
  
  NAGAI Takako
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kanazawa Medical University
Investigation for the physiological and pathological significance of the interaction between COMT deficiency and homocysteinePrincipal Investigator
- Principal Investigator
  
  KANASAKI Keizo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa Medical University

[Book] Pharma Medica: 【糖尿病性腎症の克服を目指して～up to date～】 SGLT2阻害薬と腎機能2016
- Author(s)
  金崎啓造
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 腎・高血圧の最新治療: CKDにおける糖尿病管理2016
- Author(s)
  金崎啓造
- Publisher
  フジメディカル出版
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 【糖尿病を診る　ポケット検査事典】　合併症　腎症および水・電解質代謝尿酸(尿酸クリアランスを含む)2016
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  1
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 糖尿病ケア (【患者さんがみるみる変わる!ダウンロードでそのまま使える!魔法の糖尿病患者説明シート50+α】 (第2章)糖尿病のリスク・合併症の患者説明シート16　透析になったら何がどうなる?)2016
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  4
- Publisher
  メディカ出版
- Data Source
  KAKENHI-PROJECT-26460403
[Book] Diabetes Update: SGLT・レッスン　SGLT2阻害薬が腎に及ぼす影響の可能性2016
- Author(s)
  金崎啓造、古家大祐
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 糖尿病：腎機能保護の観点からの有用性2016
- Author(s)
  金崎啓造、古家大祐
- Publisher
  日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-26460403
[Book] カレントセラピー: 糖尿病性腎症の治療　血糖コントロールの意義と新しい血糖降下薬への期待2016
- Author(s)
  金崎啓造
- Publisher
  ライフメディコム
- Data Source
  KAKENHI-PROJECT-26460403
[Book] Diabetes Frontier: 高齢者糖尿病における腎機能低下の病態と対策2016
- Author(s)
  平井太郎、金崎啓造
- Publisher
  ディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 最新医学 (【インクレチン薬による糖尿病治療の革新-基礎と臨床の架け橋-】基礎研究　インクレチンの腎臓への作用)2016
- Author(s)
  金崎啓造
- Total Pages
  9
- Publisher
  2016
- Data Source
  KAKENHI-PROJECT-26460403
[Book] Nephrology Frontier (糖尿病腎線維化分子機構を標的とした治療戦略)2016
- Author(s)
  金崎啓造
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] Progress in Medicine (SGLT2阻害薬の問題点)2016
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  5
- Publisher
  株式会社ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 【糖尿病を診る　ポケット検査事典】　合併症　腎症および水・電解質代謝電解質2016
- Author(s)
  金崎啓造、古家大祐
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] Annual Review腎臓 (尿細管・間質障害腎線維化と内皮細胞間葉細胞分化)2016
- Author(s)
  金崎啓造
- Total Pages
  7
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 成人病と生活習慣病: 【腎機能を悪化させない日常診療】糖尿病における腎機能のみかたと対策2016
- Author(s)
  金崎啓造
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 糖尿病ケア:【透析導入を防ぐ　図解でわかる!糖尿病腎症の病態生理と患者指導】病態生理からセルフケアまで糖尿病腎症のすべて　腎臓を悪くしないための薬はあるの?2016
- Author(s)
  金崎啓造
- Publisher
  メディカ出版
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 医学のあゆみ: 妊娠高血圧腎症の発症機序においてCOMT不全が演じる役割2016
- Author(s)
  植木典和, 金崎啓造
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-26460403
[Book] 糖尿病診療マスター　（【糖尿病は回復するだろうか Part 2-腎障害は寛解するか】腎障害が止めがたいタイプとは?）2015
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26460403
[Book] エビデンスに基づくCKD診療ガイドライン2013 サブグループ、糖尿病性腎症2013
- Author(s)
  金崎啓造
- Total Pages
  2
- Publisher
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 最新医学別冊「ネフローゼ症候群」「第2章病理・病態生理:病因6.糖尿病性腎症」2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  10
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 腎と透析、糖尿病合併CKDの血圧管理腎と透析2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] ヴィジュアル糖尿病臨床のすべて糖尿病性腎症食事療法2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  8
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 糖尿病診療マスター増大号：糖尿病腎症に対するたんぱく質制限食と2型糖尿病診療における15のコントロバシー: 運動制限　異論/争論, 私の意見2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 腎と透析糖尿病腎症最新治療:The update of the therapy for diabetic nephropathy2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] エビデンスに基づくCKD診療ガイドライン2013サブグループ、糖尿病性腎症2013
- Author(s)
  金崎啓造
- Total Pages
  2
- Publisher
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 最新医学別冊「ネフローゼ症候群」「第2章　病理・病態生理：病因　6.糖尿病性腎症」2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  10
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 腎と透析、糖尿病腎症最新治療 : The update of the therapy for diabetic nephropathy2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] プラクティス:糖尿病腎症に対する食事療法2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  9
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 糖尿病診療マスター増大号:糖尿病性腎症に対するたんぱく質制限食と運動療法2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 糖尿病臨床のすべて: 糖尿病性腎症　食事療法　ヴィジュアル2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  8
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23790381
[Book] プラクティス: 糖尿病腎症に対する食事療法と運動療法2013
- Author(s)
  金崎啓造、古家大祐
- Total Pages
  9
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 糖尿病性腎症　保存期腎不全2012
- Author(s)
  金崎啓造
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 腎症の成因と病態生理　growth factor cytokine 第2章　腎症の成因と病態生理細胞外基質蓄積と血管新生異常をもたらす分子異常2012
- Author(s)
  金崎啓造、古家大祐
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23790381
[Book] オートファジーを標的とした糖尿病性腎症に対する新規治療戦略の可能性2011
- Author(s)
  金崎啓造　古家大祐
- Publisher
  MEDICINAL
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 妊娠高血圧腎症の発症分子機構2011
- Author(s)
  金崎啓造
- Total Pages
  157
- Publisher
  Annual Review Nephrology　中外医学社
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 糖尿病性腎症に対する蛋白制限食の実際　―蛋白制限食は是か非か―2011
- Author(s)
  金崎啓造、古家大祐
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 蛋白制限食は有効か,　実際に行うか2011
- Author(s)
  金崎啓造、古家大祐
- Publisher
  月刊糖尿病
- Data Source
  KAKENHI-PROJECT-23790381
[Book] VEGF・Flt1と蛋白尿・糸球体病変2011
- Author(s)
  金崎啓造
- Publisher
  腎と透析
- Data Source
  KAKENHI-PROJECT-23790381
[Book] 「Preeclampsiaモデル遺伝子改変マウスから得られた知見」2011
- Author(s)
  金崎啓造
- Publisher
  妊娠高血圧学会誌特別二次抄録
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome2024
- Author(s)
  LeBleu Valerie S、Kanasaki Keizo、Lovisa Sara、Alge Joseph L、Kim Jiha、Chen Yang、Teng Yingqi、Gerami-Naini Behzad、Sugimoto Hikaru、Kato Noritoshi、Revuelta Ignacio、Grau Nicole、Sleeman Jonathan P、Taduri Gangadhar、Kizu Akane、Rafii Shahin、Hochedlinger Konrad、Quaggin Susan E、Kalluri Raghu
- Journal Title
  
  Life Science Alliance
  
  Volume: 7 Issue: 6 Pages: e202402664-e202402664
- DOI
  10.26508/lsa.202402664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Cancer biology in diabetes update: Focusing on antidiabetic drugs2024
- Author(s)
  Kawakita Emi、Kanasaki Keizo
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 15 Issue: 5 Pages: 525-540
- DOI
  10.1111/jdi.14152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330, KAKENHI-PROJECT-23K14567
[Journal Article] Epigenetic regulation of core genes linking to diabetic nephropathy progression: Lesson from FinnDiane type 1 diabetes study2023
- Author(s)
  Makino Hirofumi、Kanasaki Keizo
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 14 Issue: 12 Pages: 1341-1343
- DOI
  10.1111/jdi.14083
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Safety and effectiveness of empagliflozin in clinical practice as monotherapy or with other glucose-lowering drugs in Japanese patients with type 2 diabetes: subgroup analysis of a 3-year post-marketing surveillance study2023
- Author(s)
  Kaku Kohei、Nakayama Yayoi、Yabuuchi Junko、Naito Yusuke、Kanasaki Keizo
- Journal Title
  
  Expert Opinion on Drug Safety
  
  Volume: 22 Issue: 9 Pages: 819-832
- DOI
  10.1080/14740338.2023.2213477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Editorial: Receptor biology and cell signaling in diabetes: volume II2023
- Author(s)
  Srivastava Swayam Prakash、Kanasaki Keizo
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 14
- DOI
  10.3389/fphar.2023.1274914
- Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Association Between Papillary Thyroid Carcinoma and Vertebral Fracture2023
- Author(s)
  Otani Hazuki、Notsu Masakazu、Yamauchi Mika、Nawata Kiyoko、Kanasaki Keizo
- Journal Title
  
  Hormone and Metabolic Research
  
  Volume: 55 Issue: 09 Pages: 592-598
- DOI
  10.1055/a-2059-8830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Progressive Thymic Hyperplasia With Graves’ Disease: A Case Report2023
- Author(s)
  Ogawa Noriko、Yomota Miwako、Notsu Masakazu、Kanasaki Keizo
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.43950
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Graves’ disease after exposure to the SARS-CoV-2 vaccine: a case report and review of the literature2023
- Author(s)
  Takedani Kai、Notsu Masakazu、Ishiai Naoto、Asami Yu、Uchida Kazuhiko、Kanasaki Keizo
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 23 Issue: 1
- DOI
  10.1186/s12902-023-01387-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] The aberrant glycolysis in kidney proximal tubule: potential therapeutic target for DKD2023
- Author(s)
  Kanasaki Keizo
- Journal Title
  
  Kidney International
  
  Volume: 104 Issue: 6 Pages: 1056-1059
- DOI
  10.1016/j.kint.2023.09.019
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Inhibition of Dipeptidyl Peptidase-4 Activates Autophagy to Promote Survival of Breast Cancer Cells via the mTOR/HIF-1α Pathway2023
- Author(s)
  Kawakita Emi、Yang Fan、Shi Sen、Takagaki Yuta、Koya Daisuke、Kanasaki Keizo
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 18 Pages: 4529-4529
- DOI
  10.3390/cancers15184529
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330, KAKENHI-PROJECT-23K14567
[Journal Article] Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis2023
- Author(s)
  Adhikari J, Hirai T, Kawakita E, Iwai K, Koya D, Kanasaki K.
- Journal Title
  
  J Diabetes Invetstig
  
  Volume: Online ahead of print. Issue: 7 Pages: 844-855
- DOI
  10.1111/jdi.14017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-22K08330
[Journal Article] Analysis of eGFR index category and annual eGFR slope association with adverse clinical outcomes using real-world Japanese data: a retrospective database study2022
- Author(s)
  Zhang Ling、Hauske Sibylle、Ono Yasuhisa、Kyaw Moe H、Steubl Dominik、Naito Yusuke、Kanasaki Keizo
- Journal Title
  
  BMJ Open
  
  Volume: 12 Issue: 2 Pages: e052246-e052246
- DOI
  10.1136/bmjopen-2021-052246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-22K08330
[Journal Article] Adenosine/adenosine type?1 receptor signaling pathway did not play dominant roles on the influence of sodium?glucose cotransporter?2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice2022
- Author(s)
  Shimada Keiji、Kanasaki Keizo、Kato Makoto、Ogura Yoshio、Takagaki Yuta、Monno Itaru、Hirai Taro、Kitada Munehiro、Koya Daisuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: Online ahead of print Issue: 6 Pages: 955-964
- DOI
  10.1111/jdi.13760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-22K08330
[Journal Article] Adenosine receptors as emerging therapeutic targets for diabetic kidney disease2022
- Author(s)
  Pak Eun Seon、Cha Jin Joo、Cha Dae Ryong、Kanasaki Keizo、Ha Hunjoo
- Journal Title
  
  Kidney Research and Clinical Practice
  
  Volume: 41 Issue: Suppl 2 Pages: S74-S88
- DOI
  10.23876/j.krcp.22.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Tumor progression with thyrotoxicosis on differentiated thyroid carcinoma due to thyrotropin receptor stimulation: is tyrosine kinase inhibitors the cause of thyroid stimulating hormone receptor antibody positivity?2022
- Author(s)
  Notsu Masakazu、Kanasaki Keizo
- Journal Title
  
  Annals of Palliative Medicine
  
  Volume: 11 Issue: 9 Pages: 2806-2809
- DOI
  10.21037/apm-22-971
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Nutrient-derived modification of mineral corticoid receptors is relevant to diabetic kidney disease progression2022
- Author(s)
  Kanasaki Keizo
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 1 Pages: 261-263
- DOI
  10.1038/s41440-022-01107-8
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Successful Control of Hypercalcemia with Sorafenib, Evocalcet, and Denosumab Combination Therapy for Recurrent Parathyroid Carcinoma2022
- Author(s)
  Makino Hirofumi、Notsu Masakazu、Asayama Itsuko、Otani Hazuki、Morita Miwa、Yamamoto Masahiro、Yamauchi Mika、Nakao Mika、Miyake Hitomi、Araki Asuka、Uchino Shinya、Kanasaki Keizo
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 22 Pages: 3383-3390
- DOI
  10.2169/internalmedicine.9261-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-11-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-21K07365, KAKENHI-PROJECT-22K08330
[Journal Article] Editorial: Receptor Biology and Cell Signaling in Diabetes2022
- Author(s)
  Srivastava Swayam Prakash、Kanasaki Keizo
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13
- DOI
  10.3389/fphar.2022.864117
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] ACTH-independent Cushing’s syndrome due to ectopic endocrinologically functional adrenal tissue caused by a GNAS heterozygous mutation: a rare case of McCune?Albright syndrome accompanied by central amenorrhea and hypothyroidism: a case report and literature review2022
- Author(s)
  Kai Takedani, Masahiro Yamamoto, Sayuri Tanaka, Shinichiro Ishihara, Takeshi Taketani, Keizo Kanasaki
- Journal Title
  
  Front Endocrinol
  
  Volume: 13 Pages: 934748-934748
- DOI
  10.3389/fendo.2022.934748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07365, KAKENHI-PROJECT-22K08330
[Journal Article] Differentiating Immune-Related Adrenal Insufficiency From Low Cardiac Output Syndrome: A Case Report2022
- Author(s)
  Tanabe Junya、Watanabe Nobuhide、Ito Mayuna、Kanasaki Keizo、Tanabe Kazuaki
- Journal Title
  
  Cureus
  
  Volume: -
- DOI
  10.7759/cureus.31349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08330
[Journal Article] Combating Diabetes and Diabetic Kidney Disease2021
- Author(s)
  Srivastava Swayam Prakash、Kanasaki Keizo、Goodwin Julie E.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12
- DOI
  10.3389/fphar.2021.716029
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Which Is a Better Skeletal Muscle Mass Index for the Evaluation of Physical Abilities: The Present Height or Maximum Height?2021
- Author(s)
  Tanaka KI, Morisato Y, Nakajima H, Kanasaki K, Sugimoto T, Kanazawa I.
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 8 Pages: 1191-1196
- DOI
  10.2169/internalmedicine.5792-20
- NAID
  130008025065
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] CD26/DPP-4: Type 2 Diabetes Drug Target with Potential Influence on Cancer Biology2021
- Author(s)
  Kawakita Emi、Koya Daisuke、Kanasaki Keizo
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 9 Pages: 2191-2191
- DOI
  10.3390/cancers13092191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy.2021
- Author(s)
  Srivastava SP, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, Dardik A, Fernandez-Hernando C, Goodwin J.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 2368-2368
- DOI
  10.1038/s41467-021-22617-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Thyroid crisis caused by metastatic thyroid cancer: an autopsy case report2021
- Author(s)
  Takedani Kai、Notsu Masakazu、Adachi Naoko、Tanaka Sayuri、Yamamoto Masahiro、Yamauchi Mika、Yamauchi Naotake、Maruyama Riruke、Kanasaki Keizo
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 21 Issue: 1 Pages: 213-213
- DOI
  10.1186/s12902-021-00875-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07446, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-21K07365
[Journal Article] STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects.2021
- Author(s)
  Parchem JG, Kanasaki K, Lee SB, Kanasaki M, Yang JL, Xu Y, Earl KM, Keuls RA, Gattone VH 2nd, Kalluri R.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 2
- DOI
  10.1172/jci.insight.141588
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Dietary Magnesium Insufficiency Induces Salt-Sensitive Hypertension in Mice Associated With Reduced Kidney Catechol-O-Methyl Transferase Activity2021
- Author(s)
  Kumagai Asako、Takeda Satoru、Sohara Eisei、Uchida Shinichi、Iijima Hiroshi、Itakura Astuo、Koya Daisuke、Kanasaki Keizo
- Journal Title
  
  Hypertension
  
  Volume: - Issue: 1 Pages: 138-150
- DOI
  10.1161/hypertensionaha.120.16377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18175, KAKENHI-PROJECT-19H03672, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Interactions among Long Non-Coding RNAs and microRNAs Influence Disease Phenotype in Diabetes and Diabetic Kidney Disease2021
- Author(s)
  Srivastava Swayam Prakash、Goodwin Julie E.、Tripathi Pratima、Kanasaki Keizo、Koya Daisuke
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 11 Pages: 6027-6027
- DOI
  10.3390/ijms22116027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Classical molecule in diabetic kidney hypertrophy is linked to defects in self-eating through fine-tuning.2021
- Author(s)
  Takagaki Y, Kanasaki K.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 12 Issue: 5 Pages: 686-688
- DOI
  10.1111/jdi.13508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Safety and tolerability of linagliptin in Asians with type 2 diabetes: a pooled analysis of 4457 patients from 21 randomized, double-blind, placebo-controlled clinical trials2021
- Author(s)
  Kanasaki Keizo、Qu Shen、Yamamoto Fumiko、Schepers Cornelia、Sani Sim?es Rafael、Yabe Daisuke、Ji Linong
- Journal Title
  
  Expert Opinion on Drug Safety
  
  Volume: 21 Issue: 3 Pages: 425-434
- DOI
  10.1080/14740338.2022.1999409
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Osteomalacia caused by atypical renal tubular acidosis with vitamin D deficiency: a case report2021
- Author(s)
  Takedani K, Notsu M, Koike S, Yamauchi M, Mori T, Sohara E, Yamauchi A, Yoshikane K, Ito T, Kanasaki K.
- Journal Title
  
  CEN Case Rep
  
  Volume: 10 Issue: 2 Pages: 294
- DOI
  10.1007/s13730-020-00561-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-19K17733, KAKENHI-PROJECT-21K08249
[Journal Article] The PKM2 activator TEPP-46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF-1α accumulation.2021
- Author(s)
  Liu H, Takagaki Y, Kumagai A, Kanasaki K, Koya D.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 12 Issue: 5 Pages: 697-709
- DOI
  10.1111/jdi.13478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Graves' disease and vertebral fracture: Possible pathogenic link in postmenopausal women.2020
- Author(s)
  Takedani K, Notsu M, Yamauchi M, Nawata K, Sugimoto T, Kanasaki K.
- Journal Title
  
  Clin Endocrinol
  
  Volume: 93 Issue: 2 Pages: 204-211
- DOI
  10.1111/cen.14208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules2020
- Author(s)
  Li J, Liu H, Takagi S, Nitta K, Kitada M, Srivastava SP, Kanasaki K et al.
- Journal Title
  
  JCI Insight.
  
  Volume: 5 Issue: 6 Pages: 6-6
- DOI
  10.1172/jci.insight.129034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Loss of Mitochondrial Control Impacts Renal Health.2020
- Author(s)
  Srivastava SP, Kanasaki K, Goodwin JE.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 11 Pages: 543973-543973
- DOI
  10.3389/fphar.2020.543973
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Metformin Mitigates DPP-4 Inhibitor-Induced Breast Cancer Metastasis via Suppression of mTOR Signaling2020
- Author(s)
  Kawakita Emi、Yang Fan、Kumagai Asako、Takagaki Yuta、Kitada Munehiro、Yoshitomi Yasuo、Ikeda Takayuki、Nakamura Yuka、Ishigaki Yasuhito、Kanasaki Keizo、Koya Daisuke
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 19 Issue: 1 Pages: 61-73
- DOI
  10.1158/1541-7786.mcr-20-0115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07407, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-21K09031, KAKENHI-PROJECT-20K21773
[Journal Article] High glucose promotes mineralization via bone morphogenetic protein 4-Smad signals in early stage of osteoblast differentiation.2020
- Author(s)
  Takeno A, Kanazawa I, Tanaka KI, Notsu M, Kanasaki K, Oono T, Ogawa Y, Sugimoto T.
- Journal Title
  
  Diabetol Int.
  
  Volume: 12 Issue: 2 Pages: 171-180
- DOI
  10.1007/s13340-020-00463-5
- NAID
  40022521768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Effect of linagliptin, a dipeptidyl peptidase-4 inhibitor, compared with the sulfonylurea glimepiride on cardiovascular outcomes in Asians with type 2 diabetes: subgroup analysis of the randomized CAROLINA trial.2020
- Author(s)
  Kadowaki T, Wang G, Rosenstock J, Yabe D, Peng Y, Kanasaki K, Mu Y, Mattheus M, Keller A, Okamura T, Johansen OE, Marx N.
- Journal Title
  
  Diabetol Int.
  
  Volume: 12 Issue: 1 Pages: 87-100
- DOI
  10.1007/s13340-020-00447-5
- NAID
  40022457440
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis.2020
- Author(s)
  Takagaki Y, Lee SM, Dongqing Z, Kitada M, Kanasaki K, Koya D
- Journal Title
  
  Autophagy.
  
  Volume: - Issue: 10 Pages: 1-10
- DOI
  10.1080/15548627.2020.1713641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline is a valuable endogenous antifibrotic peptide for kidney fibrosis in diabetes: An update and translational aspects.2020
- Author(s)
  Kanasaki K
- Journal Title
  
  J Diabetes Investig
  
  Volume: - Issue: 3 Pages: 516-526
- DOI
  10.1111/jdi.13219
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Sodium-glucose cotransporter-2 inhibitors for diabetic kidney disease: Targeting Warburg effects in proximal tubular cells.2020
- Author(s)
  Morita M, Kanasaki K.
- Journal Title
  
  Diabetes Metab
  
  Volume: 46 Issue: 5 Pages: 353-361
- DOI
  10.1016/j.diabet.2020.06.005
- NAID
  120007163834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] A case of insulin-like growth factor 2-producing gastrointestinal stromal tumor with severe hypoglycemia2020
- Author(s)
  Yamasaki H, Itawaki A, Morita M, Miyake H, Yamamoto M, Sonoyama H, Tanaka S, Notsu M, Yamauchi M, Fujii Y, Ishikawa N, Fukuda I, Ishihara S, Kanasaki K
- Journal Title
  
  BMC Endocr Disord
  
  Volume: 20 Issue: 1 Pages: 60-60
- DOI
  10.1186/s12902-020-0529-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07446, KAKENHI-PROJECT-19K08738
[Journal Article] Metabolic reprogramming by N-acetyl-seryl-aspartyl-lysyl-proline protects against diabetic kidney disease2020
- Author(s)
  Srivastava SP, Goodwin JE, Kanasaki K, Koya D.
- Journal Title
  
  Br J Pharmacol.
  
  Volume: - Issue: 16 Pages: 3691-3711
- DOI
  10.1111/bph.15087
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs2020
- Author(s)
  Srivastava SP, Goodwin JE, Kanasaki K, Koya D.
- Journal Title
  
  Genes
  
  Volume: 11 Issue: 2 Pages: 2-2
- DOI
  10.3390/genes11020211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] A pregnant woman with an autonomously functioning thyroid nodule: a case report.2020
- Author(s)
  Notsu M, Yamauchi M, Sugimoto T, Kanasaki K.
- Journal Title
  
  Gynecol Endocrinol.
  
  Volume: 36 Issue: 12 Pages: 1140-1143
- DOI
  10.1080/09513590.2020.1822798
- NAID
  120007161468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] CD‐1db/db mice: a novel type 2 diabetic mouse model with progressive kidney fibrosis2020
- Author(s)
  Mizunuma Yuiko、Kanasaki Keizo、Nitta Kyoko、Nakamura Yuka、Ishigaki Yasuhito、Takagaki Yuta、Kitada Munehiro、Li Shaolan、Liu Haijie、Li Jinpeng、Usui Isao、Aso Yoshimasa、Koya Daisuke
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 10.1111/jdi.13311 Issue: 6 Pages: 1-23
- DOI
  10.1111/jdi.13311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18015, KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance through the CXCL12/CXCR4/mTOR/TGFbeta Signaling Pathway in Breast Cancer Cells.2020
- Author(s)
  Li S, Fan Y, Kumagai A, Kawakita E, Kitada M, Kanasaki K, et al.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 3 Pages: 3-3
- DOI
  10.3390/ijms21030805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08738, KAKENHI-PROJECT-20K21773
[Journal Article] SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis.2019
- Author(s)
  Srivastava SP, Li J, Kitada M, Fujita H, Yamada Y, Goodwin JE, Kanasaki K, Koya D.
- Journal Title
  
  Cell Death Dis.
  
  Volume: - Issue: 10
- DOI
  10.1038/s41419-018-1057-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] AMP-Activated Protein (AMPK) in Pathophysiology of Pregnancy Complications.2019
- Author(s)
  Kumagai A, Itakura A, Koya D, Kanasaki K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: - Issue: 10 Pages: 3076-3076
- DOI
  10.3390/ijms19103076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] βklotho is essential for the anti-endothelial mesenchymal transition effects of N-acetyl-seryl-aspartyl-lysyl-proline.2019
- Author(s)
  Gao R, Kanasaki K, Li J, Kitada M, Okazaki T, Koya D.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 9 Issue: 5 Pages: 1029-1038
- DOI
  10.1002/2211-5463.12638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-19K08738
[Journal Article] Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney.2019
- Author(s)
  Srivastava SP, Hedayat AF, Kanasaki K, and Goodwin JE.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 10 Pages: 904-904
- DOI
  10.3389/fphar.2019.00904
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Relevance of Autophagy Induction by Gastrointestinal Hormones: Focus on the Incretin-Based Drug Target and Glucagon.2019
- Author(s)
  Kanasaki K, Kawakita E, and Koya D.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 10 Pages: 476-476
- DOI
  10.3389/fphar.2019.00476
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] Effect of switching to teneligliptin from other dipeptidyl peptidase-4 inhibitors on glucose control and renoprotection in type 2 diabetes patients with diabetic kidney disease.2019
- Author(s)
  Kitada M, Ogura Y, Nitta K, Fujii M, Kanasaki K, Konishi K, Iida Y, Nakagawa A, Koya D.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: - Issue: 3 Pages: 706-13
- DOI
  10.1111/jdi.12917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-19K08738
[Journal Article] Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice.2019
- Author(s)
  Takagaki Y, Shi S, Katoh M, Kitada M, Kanasaki K, and Koya D.
- Journal Title
  
  Sci Rep
  
  Volume: 1 Issue: 1 Pages: 7519-7519
- DOI
  10.1038/s41598-019-43730-5
- Data Source
  KAKENHI-PROJECT-19K08738
[Journal Article] N-Acetyl-seryl-aspartyl-lysyl-proline is a potential biomarker of renal function in normoalbuminuric diabetic patients with eGFR above 30 ml/min/1.73 m2.2019
- Author(s)
  Nitta K, Nagai T, Mizunuma Y, Kitada M, Nakagawa A, Sakurai M, Toyoda M, Haneda M, Kanasaki K, Koya D.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: - Issue: 8 Pages: 1004-12
- DOI
  10.1007/s10157-019-01733-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-19K08738
[Journal Article] Role of dietary amino acid balance in diet restriction-mediated lifespan extension, renoprotection, and muscle weakness in aged mice.2018
- Author(s)
  Yoshida S, Yamahara K, Kume S, Koya D, Yasuda-Yamahara M, Takeda N, Osawa N, Chin-Kanasaki M, Adachi Y, Nagao K, Maegawa H, Araki SI.
- Journal Title
  
  Aging Cell.
  
  Volume: 17 Issue: 4
- DOI
  10.1111/acel.12796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15998, KAKENHI-PROJECT-16K15472
[Journal Article] Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet.2018
- Author(s)
  Takagi S, Li J, Takagaki Y, Kitada M, Nitta K, Takasu T, Kanasaki K, Koya D.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 9 Issue: 5 Pages: 1025-1032
- DOI
  10.1111/jdi.12802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial?Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis2018
- Author(s)
  Yang Fan、Takagaki Yuta、Yoshitomi Yasuo、Ikeda Takayuki、Li Jinpeng、Kitada Munehiro、Kumagai Asako、Kawakita Emi、Shi Sen、Kanasaki Keizo、Koya Daisuke
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 4 Pages: 735-746
- DOI
  10.1158/0008-5472.can-18-0620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16214, KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-19K08738
[Journal Article] A low-protein diet exerts a beneficial effect on diabetic status and prevents diabetic nephropathy in Wistar fatty rats, an animal model of type 2 diabetes and obesity.2018
- Author(s)
  Kitada M, Ogura Y, Suzuki T, Monno I, Kanasaki K, Watanabe A, Koya D.
- Journal Title
  
  Nutr Metab (Lond).
  
  Volume: - Issue: 1
- DOI
  10.1186/s12986-018-0255-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] A ketogenic amino acid rich diet benefits mitochondrial homeostasis by altering the AKT/4EBP1 and autophagy signaling pathways in the gastrocnemius and soleus.2018
- Author(s)
  Li J, Kanasaki M, Xu L, Kitada M, Nagao K, Adachi Y, Jinzu H, Noguchi Y, Kohno M, Kanasaki K, Koya D
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: S0304-4165 Issue: 7 Pages: 30075-8
- DOI
  10.1016/j.bbagen.2018.03.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] FGFR1 is essential for N-acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p2018
- Author(s)
  Hu Q, Li J, Nitta K, Kitada M, Nagai T, Kanasaki K, Koya D.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 495 Issue: 3 Pages: 2214-2220
- DOI
  10.1016/j.bbrc.2017.12.089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats2018
- Author(s)
  Ogura Yoshio、Kitada Munehiro、Monno Itaru、Kanasaki Keizo、Watanabe Ai、Koya Daisuke
- Journal Title
  
  Redox Report
  
  Volume: 23 Issue: 1 Pages: 153-159
- DOI
  10.1080/13510002.2018.1487174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16104, KAKENHI-PROJECT-16K15472
[Journal Article] The Effect of Piceatannol from Passion Fruit (Passiflora edulis) Seeds on Metabolic Health in Humans.2018
- Author(s)
  Kitada M, Ogura Y, Maruki-Uchida H, Sai M, Suzuki T, Kanasaki K, Hara Y, Seto H, Kuroshima Y, Monno I, Koya D
- Journal Title
  
  Nutrients.
  
  Volume: 9 Issue: 10 Pages: 1142-1142
- DOI
  10.3390/nu9101142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Dipeptidyl peptidase-4 inhibition and renoprotection: the role of antifibrotic effects.2017
- Author(s)
  Takagaki Y, Koya D, Kanasaki K.
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 26 Pages: 56-66
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Catechol-O-methyltransferase deficiency leads to hypersensitivity of the pressor response against angiotensin II2017
- Author(s)
  Norikazu Ueki, Keizo Kanasaki, Megumi Kanasaki, Satoru Takeda, Daisuke Koya
- Journal Title
  
  Hypertension
  
  Volume: In Press Issue: 6 Pages: 1156-1164
- DOI
  10.1161/hypertensionaha.117.09247
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-16K15472
[Journal Article] FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway2017
- Author(s)
  Li J, Shi S, Srivastava SP, Kitada M, Nagai T, Nitta K, Kohno M, Kanasaki K, Koya D
- Journal Title
  
  Cell Death Dis.
  
  Volume: 8 Issue: 8 Pages: e2965-e2965
- DOI
  10.1038/cddis.2017.353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Cyclic and intermittent very low-protein diet can have beneficial effects against advanced diabetic nephropathy in Wistar fatty (fa/fa) rats, an animal model of type 2 diabetes and obesity.2017
- Author(s)
  Kitada M, Ogura Y, Suzuki T, Monnno I, Kanasaki K, Watanabe A, Koya D.
- Journal Title
  
  Nephrology (Carlton).
  
  Volume: 22 Issue: 12 Pages: 1030-1034
- DOI
  10.1111/nep.13152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice.2017
- Author(s)
  Kanasaki M, Srivastava SP, Yang F, Xu L, Kudoh S, Kitada M, Ueki N, Kim H, Li J, Takeda S, Kanasaki K, Koya D.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41598-017-08513-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Dipeptidyl peptidase-4 inhibition and renoprotection: the role of antifibrotic effects.2017
- Author(s)
  Takagaki Y, Koya D, Kanasaki K.
- Journal Title
  
  Curr Opin Nephrol Hypertens.
  
  Volume: 26 Issue: 1 Pages: 56-66
- DOI
  10.1097/mnh.0000000000000291
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Anagliptin ameliorates albuminuria and urinary liver-type fatty acid-binding protein excretion in patients with type 2 diabetes with nephropathy in a glucose-lowering-independent manner.2017
- Author(s)
  Kitada M, Tsuda SI, Konishi K, Takeda-Watanabe A, Fujii M, Kanasaki K, Nishizawa M, Nakagawa A, Koya D
- Journal Title
  
  BMJ Open Diabetes Res Care.
  
  Volume: 5 Issue: 1 Pages: e000391-e000391
- DOI
  10.1136/bmjdrc-2017-000391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472
[Journal Article] Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis.2016
- Author(s)
  Srivastava SP, Shi S, Kanasaki M, Nagai T, Kitada M, He J, Nakamura Y, Ishigaki Y, Kanasaki K, Koya D.
- Journal Title
  
  Sci Rep
  
  Volume: 18 Issue: 1 Pages: 29884-29884
- DOI
  10.1038/srep29884
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-16K15472
[Journal Article] A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity.2016
- Author(s)
  Kitada M, Ogura Y, Suzuki T, Sen S, Lee SM, Kanasaki K, Kume S, Koya D.
- Journal Title
  
  Diabetologia
  
  Volume: in press Issue: 6 Pages: 1307-17
- DOI
  10.1007/s00125-016-3925-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-26460403
[Journal Article] Linagliptin but not Sitagliptin inhibited transforming growth factor-β2-induced endothelial DPP-4 activity and the endothelial-mesenchymal transition2016
- Author(s)
  Shi S, Kanasaki K, Koya D
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 26 Issue: 1 Pages: 184-190
- DOI
  10.1016/j.bbrc.2016.01.154
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028
[Journal Article] Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen2016
- Author(s)
  Nitta K, Shi S, Nagai T, Kanasaki M, Kitada M, Srivastava SP, Haneda M, Kanasaki K, Koya D.
- Journal Title
  
  Biomed Res Int
  
  Volume: 2016:9172157 Pages: 9172157-9172157
- DOI
  10.1155/2016/9172157
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028
[Journal Article] MicroRNA148b-3p inhibits mTORC1-dependent apoptosis in diabetes by repressing TNFR2 in proximal tubular cells.2016
- Author(s)
  Kuwagata S, Kume S, Chin-Kanasaki M, Araki H, Araki S, Nakazawa J, Sugaya T, Koya D, Haneda M, Maegawa H, Uzu T.
- Journal Title
  
  Kidney Int.
  
  Volume: 90 Issue: 6 Pages: 1211-1225
- DOI
  10.1016/j.kint.2016.06.036
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25713033, KAKENHI-PROJECT-16K15472
[Journal Article] A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity2016
- Author(s)
  Kitada M, Ogura Y, Suzuki T, Sen S, Lee SM, Kanasaki K, Kume S, Koya D.
- Journal Title
  
  Diabetologia
  
  Volume: in Press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Concerted efforts to combat diabetic complications.2016
- Author(s)
  Kanasaki K
- Journal Title
  
  Kidney Int
  
  Volume: 89 Issue: 2 Pages: 269-271
- DOI
  10.1016/j.kint.2015.12.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Dipeptidyl peptidase-4 and kidney fibrosis in diabetes.2016
- Author(s)
  Shi S, Koya D, Kanasaki K.
- Journal Title
  
  Fibrogenesis Tissue Repair
  
  Volume: 9 Issue: 1 Pages: 1-10
- DOI
  10.1186/s13069-016-0038-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414
[Journal Article] The relevance of the renin-angiotensinsystem in the development of drugs to combat preeclampsia2015
- Author(s)
  Norikazu Ueki, Satoru Takeda, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  International Journal of Endocrinology
  
  Volume: 該当なし
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: A multicenter, randomized clinical trial2015
- Author(s)
  1.Kato S, Maruyama S, Makino H, Wada J, Ogawa D, Uzu T, Araki H, Koya D, Kanasaki K, Oiso Y, Goto M, Nishiyama A, Kobori H, Imai E, Ando M, and Matsuo S
- Journal Title
  
  Clin Experim Nephrol
  
  Volume: 19 Issue: 6 Pages: 1098-1106
- DOI
  10.1007/s10157-015-1106-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460896, KAKENHI-PROJECT-26460403
[Journal Article] [Kidney fibrosis and endothelial injury].2015
- Author(s)
  Kanasaki K.
- Journal Title
  
  Nihon Jinzo Gakkai Shi
  
  Volume: 57 Pages: 1200-1205
- NAID
  40020642428
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial2015
- Author(s)
  Sawako Kato, Shoichi Maruyama, Hirofumi Makino, Jun Wada, Daisuke Ogawa, Takashi Uzu, Hisazumi Araki, Daisuke Koya, Keizo Kanasaki, Yutaka Oiso, Motomitsu Goto, Akira Nishiyama, Hiroyuki Kobori, Enyu Imai, Masahiko Ando, Seiichi Matsuo
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Interactions of DPP-4 and integrin β1 influences endothelial-to mesenchymal transition.2015
- Author(s)
  Shi S, Srivastava SP, Kanasaki M, He J, Kitada M, Nagai T, Nitta K, Takagi S, Kanasaki K, Koya D.
- Journal Title
  
  Kidney Int.
  
  Volume: - Issue: 3 Pages: 479-489
- DOI
  10.1038/ki.2015.103
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25282028
[Journal Article] The biological significance of angiotensisn-converting enzyme inhibition to combat kidney fibrosis2015
- Author(s)
  Nagai T, Nitta K, Kanasaki M, Koya D, Kanasaki K.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 19 Issue: 1 Pages: 65-74
- DOI
  10.1007/s10157-014-1000-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] The relevance of the Renin-Angiotensin system in the development of drugs to combat preeclampsia2015
- Author(s)
  Ueki N, Takeda S, Koya D, Kanasaki K
- Journal Title
  
  Int J Endocrinol
  
  Volume: 572713 Pages: 572713-572713
- DOI
  10.1155/2015/572713
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline inhibits diabetes-associated kidney fibrosis and endothelial-mesenchymal transition2014
- Author(s)
  Takako Nagai, Megumi Kanasaki, Swayam Prakash Srivastava, Yuka Nakamura, Yasuhito Ishigaki, Munehiro Kitada, Sen Shi, Keizo Kanasaki, Daisuke Koya
- Journal Title
  
  BioMed Research International
  
  Volume: 2014 Pages: 696475-696475
- DOI
  10.1155/2014/696475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-24659264, KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen2014
- Author(s)
  Keizo Kanasaki , Sen Shi , Megumi Kanasaki, Jinhua He, Takako Nagai, Yuka Nakamura, Yasuhito Ishigaki, Munehiro Kitada, Swayam Prakash Srivastava, Daisuke Koya
- Journal Title
  
  Diabetes
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Low-protein diet for diabetic nephropathy2014
- Author(s)
  Otoda T, Kanasaki K, Koya D
- Journal Title
  
  Curr Diab Rep
  
  Volume: 14 Issue: 9 Pages: 523-533
- DOI
  10.1007/s11892-014-0523-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Specific Activation of K-RasG12D Allele in the Bladder Urothelium Results in Lung Alveolar and Vascular Defects2014
- Author(s)
  Keizo Kanasaki, Francisco Ayala de la Peña, Megumi Kanasaki, Sylvia Vong, Carlota Rovira, Raghu Kalluri
- Journal Title
  
  Plos One
  
  Volume: 9(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes.2014
- Author(s)
  Kanasaki K, Nagai T, Nitta K, Kitada M, Koya D.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 2014 Pages: 1-11
- DOI
  10.3389/fphar.2014.00070
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes.2014
- Author(s)
  Yasuda M, Tanaka Y, Kume S, Morita Y, Chin-Kanasaki M, Araki H, Isshiki K, Araki SI, Koya D, Haneda M, Kashiwagi A, Maegawa H, Uzu T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1842 Issue: 7 Pages: 1097-1108
- DOI
  10.1016/j.bbadis.2014.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24890089, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-25713033
[Journal Article] Combating Kidney Fibrosis2014
- Author(s)
  Keizo Kanasaki, Akito Maeshima, Gangadhar Taduri, Ignacio Revuela.
- Journal Title
  
  Biomed Res Int
  
  Volume: 該当なし Pages: 1-2
- DOI
  10.1155/2014/679154
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Clinical therapeutic strategies for early stage of diabetic kidney disease.2014
- Author(s)
  Kitada M, Kanasaki K, Koya D
- Journal Title
  
  World J Diabetes.
  
  Volume: 5 Issue: 3 Pages: 342-356
- DOI
  10.4239/wjd.v5.i3.342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-26460403
[Journal Article] Interventions against nutrient-sensing pathways represent an emerging new therapeutic approach for diabetic nephropathy2014
- Author(s)
  Koya D, Kitada M, Kume S, Kanasaki K
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis.2014
- Author(s)
  Takako Nagai,Kyoko Nitta,Megumi Kanasaki,Keizo Kanasaki,Daisuke Koya
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: volume19 Pages: 65-74
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659264
[Journal Article] Activation of K-RasG12D Allele in the Bladder Urothelium Results in Lung Alveolar and Vascular Defects2014
- Author(s)
  Keizo Kanasaki, Francisco Ayala de la Peña, Megumi Kanasaki, Sylvia Vong, Carlota Rovira, Raghu Kalluri
- Journal Title
  
  Plos One
  
  Volume: 該当なし Issue: 4 Pages: e95888-e95888
- DOI
  10.1371/journal.pone.0095888
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] The Role of Ubiquitination and Sumoylation in Diabetic Nephropathy2014
- Author(s)
  Gao C, Huang W, Kanasaki K, Xu Y
- Journal Title
  
  Biomed Res Int
  
  Volume: 該当なし Pages: 1-11
- DOI
  10.1155/2014/160692
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] N-acetyl-seryl-aspartyl-lysyl-proline: A valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes2014
- Author(s)
  Keizo Kanasaki, Takako Nagai, Kyoko Nitta, Munehiro Kitada, Daisuke Koya
- Journal Title
  
  Frontier in Pharmacology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] N-acetyl-seryl- aspartyl-lysyl-proline : A valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes2014
- Author(s)
  Keizo Kanasaki, Takako Nagai, Kyoko Nitta, Munehiro Kitada, Daisuke Koya
- Journal Title
  
  Frontier Pharmacology
  
  Volume: 70. eCollection
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Linagriptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabeticmice by inhibiting endothelial-to mesenchymal transition in a therapeutic regimen.2014
- Author(s)
  Kanasaki K, Shi S, Kanasaki M, He J, Nagai T, Nakamura Y, Ishigaki Y, Kitada M, Srivastava SP, Koya D.
- Journal Title
  
  Diabetes.
  
  Volume: 63 Issue: 6 Pages: 2120-2131
- DOI
  10.2337/db13-1029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] Cancer Biology in Diabetes2014
- Author(s)
  Sen Shi, Yanzheng He, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 5 Issue: 3 Pages: 251-264
- DOI
  10.1111/jdi.12208
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Lipid mediators in Diabetic Nephropathy2014
- Author(s)
  Swayam Prakash Srivastava, Sen Shi, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  Fibrogenesis&Tissue Repair
  
  Volume: 該当なし Issue: 1
- DOI
  10.1186/1755-1536-7-12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460403
[Journal Article] Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen2014
- Author(s)
  Keizo Kanasaki, Sen Shi, Megumi Kanasaki, Jinhua He, Takako Nagai, Yuka Nakamura, Yasuhito Ishigaki, Munehiro Kitada, Swayam Prakash Srivastava, Daisuke Koya
- Journal Title
  
  Diabetes
  
  Volume: 63(6) Pages: 2120-2131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Three　ileus cases associated with the use of DPP-4 inhibitors in diabetic patients.2013
- Author(s)
  Keizo Kanasaki他
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-24659264
[Journal Article] Sirtuins as possible drug targets in type 2 diabetes.2013
- Author(s)
  Kitada M, Kume S, Kanasaki K, Takeda-Watanabe A, Koya D.
- Journal Title
  
  Curr Drug Targets
  
  Volume: 14 Pages: 622-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282028
[Journal Article] Angiogenic defects in preeclampsia : What is known and how are such defects relevant to preeclampsia pathogenesis?2013
- Author(s)
  Keizo Kanasaki, Megumi Kanasaki
- Journal Title
  
  Hypertension Research in Pregnancy
  
  Volume: 1 Pages: 57-65
- NAID
  130004638238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Angiogenic defects in preeclampsia: What is known and how are such defects relevant to preeclampsia pathogenesis?2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Hypertension Research in Pregnancy
  
  Volume: in press
- NAID
  130004638238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590189
[Journal Article] Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP1c Tg mice fed high-fat and high-fructose diet2013
- Author(s)
  Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka T
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 305(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions.2013
- Author(s)
  Yamahara K, Kume S, Koya D, Tanaka Y, Morita Y, Chin-Kanasaki M, Araki H, Isshiki K, Araki S, Haneda M, Matsusaka T, Kashiwagi A, Maegawa H, Uzu T.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 24 Issue: 11 Pages: 1769-81
- DOI
  10.1681/asn.2012111080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25713033
[Journal Article] Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 32013
- Author(s)
  Sugimoto H, Lebleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R
- Journal Title
  
  Nature Medicine
  
  Volume: 19 Issue: 7 Pages: 810-1
- DOI
  10.1038/nm.3081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Diabetic Nephropathy: The Role of Inflammation in Fibroblasts Activation and Kidney Fibrosis2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: On line
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590189
[Journal Article] Three ileus cases associated with the use of DPP-4 inhibitors in diabetic patients.2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590189
[Journal Article] Loss of &b1-Integrin from Urothelium Results in Overactive Bladder and Incontinence in Mice: A Mechanosensory rather than Structural Phenotype2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  FASB J
  
  Volume: in Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] The administration of pitavastatin augments creatinine clearance associated with the reduction in oxidative stress parameters : acute and early effects2013
- Author(s)
  Hirokazu Kakuda, Keizo Kanasaki, Daisuke Koya, Noboru Takekoshi
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 17(2) Pages: 240-247
- NAID
  10031169472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation.2013
- Author(s)
  Kitada M, Kume S, Takeda-Watanabe A, Tsuda S, Kanasaki K, Koya D.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1830(10) Issue: 10 Pages: 4820-4827
- DOI
  10.1016/j.bbagen.2013.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] Role of the Endothelial-to-mesenchymal Transition in Renal Fibrosis of Chronic Kidney Disease2013
- Author(s)
  Jianhua He, Yong Xu, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  2013 Clin Exp Nephrol Clin Exp Nephrol
  
  Volume: 17(4) Issue: 4 Pages: 488-497
- DOI
  10.1007/s10157-013-0781-0
- NAID
  10031195312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 32013
- Author(s)
  Sugimoto H, Lebleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R
- Journal Title
  
  Nat Med
  
  Volume: 19(7) Pages: 810-811
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] The biological consequence2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Nephrology Dialysis and Transplantation
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590189
[Journal Article] The biological consequence of obesity on the kidney2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Nephrology Dialysis and Transplantation
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction2013
- Author(s)
  Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110(27) Pages: 11109-11114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Interventions against nutrient-sensing pathways represent an emerging new therapeutic approach for diabetic nephropathy2013
- Author(s)
  Koya D, Kitada M, Kume S, Kanasaki K
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 18(2) Issue: 2 Pages: 210-213
- DOI
  10.1007/s10157-013-0908-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-25670414, KAKENHI-PROJECT-26460403
[Journal Article] Sirtuins as possible drug targets in type 2 diabetes2013
- Author(s)
  Kitada M, Kume S, Kanasaki K, Takeda-Watanabe A, Koya D
- Journal Title
  
  Curr Drug Targets
  
  Volume: 14(6) Pages: 622-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Loss of b1-Integrin from Urothelium Results in Overactive Bladder and Incontinence in Mice2013
- Author(s)
  Keizo Kanasaki, Weiqun Yu, Maximilian von Bodungen, John D. Larigakis, Megumi Kanasaki, Francisco Ayala de la Pena, Raghu Kalluri, Warren G. Hill
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 5 Pages: 1950-61
- DOI
  10.1096/fj.12-223404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-24790329
[Journal Article] MicroRNAs in kidney fibrosis: roles on EMT and EndMT program2013
- Author(s)
  Swayam Prakash Srivastava, Daisuke Koya and Keizo Kanasaki
- Journal Title
  
  BioMed Research International
  
  Volume: 2013:125469 Pages: 125469-125469
- DOI
  10.1155/2013/125469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP1c Tg mice fed high-fat and high-fructose diet2013
- Author(s)
  Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 305 Issue: 11 Pages: E1415-E1425
- DOI
  10.1152/ajpendo.00419.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-24390230, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-25670414
[Journal Article] Sirtuins and renal diseases: relationship with aging and diabetic nephropathy2013
- Author(s)
  Kitada M.
- Journal Title
  
  Clin Sci (Lond)
  
  Volume: 124(3) Issue: 3 Pages: 153-64
- DOI
  10.1042/cs20120190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-23890085, KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-25670414
[Journal Article] Inflammation and oxidative stress in diabetic nephropathy : new insights on its inhibition as new therapeutic targets2013
- Author(s)
  Mima A
- Journal Title
  
  J Diabetes Res
  
  Volume: 該当なし Pages: 207140-207140
- DOI
  10.1155/2014/207140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24890148, KAKENHI-PROJECT-26460403, KAKENHI-PROJECT-26461230
[Journal Article] Diabetic Nephropathy: The Role of Inflammation in Fibroblasts Activation and Kidney Fibrosis2013
- Author(s)
  Keizo Kanasaki, Gangadhar Taduri, Daisuke Koya
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 4 Pages: 7-7
- DOI
  10.3389/fendo.2013.00007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage.2013
- Author(s)
  Takeda N, Kume S, Tanaka Y, Morita Y, Chin-Kanasaki M, Araki H, Isshiki K, Araki S, Haneda M, Koya D, Kashiwagi A, Maegawa H, Uzu T.
- Journal Title
  
  Am J Pathol.
  
  Volume: 183 Issue: 3 Pages: 774-85
- DOI
  10.1016/j.ajpath.2013.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] Angiogenic defects in preeclampsia: What is known and how are such defects relevant to preeclampsia pathogenesis?2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Hypertension Research in Pregnancy
  
  Volume: in press
- NAID
  130004638238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation2013
- Author(s)
  Kitada M, Kume S, Takeda-Watanabe A, S T, Kanasaki K, Koya D
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1830(10) Pages: 4820-4827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules.2013
- Author(s)
  Xu L, Kanasaki M, He J, Kitada M, Nagao K, Jinzu H, Noguchi Y, Maegawa H, Kanasaki K, Koya D.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1832(10) Issue: 10 Pages: 1605-1612
- DOI
  10.1016/j.bbadis.2013.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591218, KAKENHI-PROJECT-24790329, KAKENHI-PROJECT-25282028, KAKENHI-PROJECT-25670414
[Journal Article] Three ileus cases associated with the use of DPP-4 inhibitors in diabetic patients.2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] The biological consequence of obesity on the kidney2013
- Author(s)
  Keizo Kanasaki, Munehiro Kitada, Megumi Kanasaki, Daisuke Koya
- Journal Title
  
  Nephrology Dialysis and Transplantation
  
  Volume: Suppl 4 Issue: suppl 4 Pages: iv1-iv7
- DOI
  10.1093/ndt/gft098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-25282028
[Journal Article] Loss of &b1-Integrin from Urothelium Results in Overactive Bladder and Incontinence in Mice: A Mechanosensory rather than Structural Phenotype2013
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  FASB J
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590189
[Journal Article] Sirtuins and renal diseases : relationship with aging and diabetic nephropathy2013
- Author(s)
  Kitada M, Kume S, Takeda-Watanabe A, Kanasaki K, Koya D
- Journal Title
  
  Clin Sci
  
  Volume: 124(3) Pages: 153-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Angiogenic defects in preeclampsia: What is known and how are such defects relevant to preeclampsia pathogenesis?2013
- Author(s)
  Keizo Kanasaki, Megumi Kanasaki
- Journal Title
  
  Hypertension Research in Pregnancy
  
  Volume: 1 Pages: 57-65
- NAID
  130004638238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Pathophysiology of the aging kidney and therapeutic interventions2012
- Author(s)
  Keizo Kanasaki, Munehiro Kitada, Daisuke Koya
- Journal Title
  
  Hypertension Research
  
  Volume: 35(12) Pages: 1121-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Pathophysiology of the aging kidney and therapeutic interventions2012
- Author(s)
  Keizo Kanasaki
- Journal Title
  
  Hypertension Research
  
  Volume: 35(12) Issue: 12 Pages: 1121-8
- DOI
  10.1038/hr.2012.159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381, KAKENHI-PROJECT-24590189
[Journal Article] Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis2012
- Author(s)
  Sugimoto H, Lebleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R
- Journal Title
  
  Nat Med
  
  Volume: 18(3) Pages: 396-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] SIRT1 inactivation induces inflammation through the dysregulation of autophagy in human THP-1 cells2012
- Author(s)
  Takeda-Watanabe A, Kitada M, Kanasaki K, Koya D
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 427(1) Pages: 191-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Diabetic angiopathy and angiogenic defects.2012
- Author(s)
  Xu L.
- Journal Title
  
  Fibrogenesis Tissue Repair.
  
  Volume: 1;5(1) Issue: 1 Pages: 13-13
- DOI
  10.1186/1755-1536-5-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors.2011
- Author(s)
  Kanasaki M
- Journal Title
  
  Fibrogenesis Tissue Repair
  
  Volume: 4;25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] Elevation of the anti-fibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline : a blood pressure–independent beneficial effect of angiotensin I–converting enzyme inhibitors2011
- Author(s)
  Megumi Kanasaki, Takako Nagai, Munehiro Kitada, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  Fibrogenesis&Tissue Repai
  
  Volume: 4 Issue: 1 Pages: 25-25
- DOI
  10.1186/1755-1536-4-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Journal Article] The Biology of Angiotensin-Converting Enzyme in Kidney Fibrosis
- Author(s)
  Takako Nagai, Kyoko Nitta, Megumi Kanasaki, Daisuke Koya, Keizo Kanasaki
- Journal Title
  
  CEN(invited review)
  
  Volume: (in Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 糖尿病性腎症治療の新展開－透析導入予防のために：DPP-4阻害薬の位置付け2023
- Author(s)
  金崎啓造
- Organizer
  第57回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-22K08330
[Presentation] 臨床医が知っておくべき糖尿病の基礎：糖尿病性腎症発症機序における最新の知見2023
- Author(s)
  金崎啓造
- Organizer
  第57回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-22K08330
[Presentation] 腎障害を合併した２型糖尿病の診療～SGLT2阻害薬がもたらしたインパクト～2022
- Author(s)
  金崎啓造
- Organizer
  第33回日本糖尿病性腎症研究会
- Data Source
  KAKENHI-PROJECT-22K08330
[Presentation] Dietary magnesium insufficiency induces salt-sensitive hypertension in mice associated with reduced kidney COMT activity.2022
- Author(s)
  Keizo KANASAKI
- Organizer
  The 19th Japan-Korea Diabetic Nephropathy Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] ＤＫＤ基礎研究から臨床へ-今後の課題-2022
- Author(s)
  金崎啓造
- Organizer
  第65回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08330
[Presentation] Symposium 1:Pathophysiology of PE(1)：COMT in the biology of preeclampsia2021
- Author(s)
  Keizo KANASAKI
- Organizer
  第22回世界妊娠高血圧学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 糖尿病治療薬と癌2020
- Author(s)
  金崎啓造
- Organizer
  第35回日本糖尿病合併症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] The link between diabetic nephropathy and cardiovascular complications2020
- Author(s)
  金崎啓造
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 糖尿病性腎症の線維化分子機構を標的とした治療戦略2020
- Author(s)
  金崎啓造
- Organizer
  第93回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 腎保護効果を期待できる薬物治療の新展開;post SGLT2 inhibitor Eraを見据えて2020
- Author(s)
  金崎啓造
- Organizer
  第54回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 糖尿病状態が惹起する腎障害に対してSGLT2阻害薬が演じる腎保護メカニズム2020
- Author(s)
  金崎啓造
- Organizer
  第20回抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 合併症抑止を見据えた糖尿病診療の新機軸2020
- Author(s)
  金崎啓造
- Organizer
  第123回日本内科学会中国地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] 教育講演：糖尿病腎症の診断と治療、2019
- Author(s)
  金崎啓造
- Organizer
  第53回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] シンポジウム：　明らかになってきたSGLT2阻害薬による腎保護効果の分子機構2019
- Author(s)
  金崎啓造
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] シンポジウム：The molecular mechanisms of kidney fibrosis in diabetes: alteration in glucosw metabolism2019
- Author(s)
  金崎啓造
- Organizer
  第62回日本腎臓学会学術総会　（JSN/ERA-EDTA joint symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] シンポジウム：DPP-4inhibitor: light and dark side2019
- Author(s)
  金崎啓造
- Organizer
  第62回日本糖尿病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] シンポジウム：糖尿病から見たCVD2019
- Author(s)
  金崎啓造
- Organizer
  第64回日本透析医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08738
[Presentation] ThePathological ROle of ENdothelial DPP-4 in DIabetic Kidney Fibrosis2017
- Author(s)
  Keizo Kanasaki
- Organizer
  2017 Asia Islet Biology and Incretin Symposium
- Place of Presentation
  Korea, Seoul
- Year and Date
  2017-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 1型糖尿病CD-1マウスにおけるEmpagliflozinの腎保護効果の検討2016
- Author(s)
  高木晋, 島田圭司, 高垣雄太, 新田恭子, 小倉慶雄, 金崎啓造, 古家大祐
- Organizer
  第59回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病性腎症の臨床の新たな展開新たな糖尿病治療薬による腎保護の可能性2016
- Author(s)
  金崎啓造
- Organizer
  第46回日本腎臓学会西部大会
- Place of Presentation
  シーガイアコンベンションセンター(宮崎県宮崎市)
- Year and Date
  2016-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Linagliptin but not Sitagliptin inhibited transforming growth factor-β2-induced endothelial DPP-4 activity and the endothelial-mesenchymal transition.2016
- Author(s)
  Shi S, Kanasaki K, Koya D.
- Organizer
  American Diabetes Association's 76th Scientific Sessions
- Place of Presentation
  New Orleans, LO, USA
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT不全はangiotensin IIに対する昇圧感受性亢進の原因となる2016
- Author(s)
  植木典和, 金崎めぐみ, 板倉敦夫, 竹田省, 古家大祐, 金崎啓造
- Organizer
  第59回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病尿細管障害モデルにおけるDPP-4の病理学的意義の検討2016
- Author(s)
  高垣雄太, 高木晋, 加藤誠, 金崎啓造, 古家大祐
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病腎症の発症・進展にはSirt3の活性低下に関連したミトコンドリア酸化ストレスが関与する2016
- Author(s)
  小倉慶雄, 北田宗弘, 鈴木妙子, 渡邊愛, 金崎啓造, 中川淳, 古家大祐
- Organizer
  第31回日本糖尿病合併症学会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 高度低たんぱく質食は進展した2型糖尿病腎症において腎保護効果を発揮する2016
- Author(s)
  北田宗弘, 鈴木妙子, 小倉慶雄, 金崎啓造, 西澤誠, 中川淳, 古家大祐
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT不全はangiotensin IIに対する昇圧感受性亢進の原因となる2016
- Author(s)
  金崎啓造, 植木典和, 古家大祐
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT不全はangiotensin IIに対する昇圧感受性亢進の原因となる2016
- Author(s)
  植木典和, 金崎めぐみ, 板倉敦夫, 竹田省, 古家大祐, 金崎啓造
- Organizer
  第53回日本臨床分子医学会学術総会
- Place of Presentation
  東京国際フォーラム(東京都千代田区）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 創薬を目指した糖尿病性腎症研究の展望糖尿病における腎線維化への取り組み　抗TGFβエフェクター分子を中心に2016
- Author(s)
  金崎啓造
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] カロリー制限は2型糖尿病ラット腎症において、抗酸化作用と腎保護効果を発揮する2016
- Author(s)
  小倉慶雄, 北田宗弘, 鈴木妙子, 金崎啓造, 西澤誠, 中川淳, 古家大祐
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Ipragliflozinは高脂肪食による腎尿細管ミトコンドリアの形態異常を改善し、腎障害の進展を抑制する2016
- Author(s)
  高木晋, 新田恭子, 永井貴子, 金崎啓造, 古家大祐
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice2016
- Author(s)
  Keizo Kanasaki, Megumi Kanasaki,
- Organizer
  52nd EASD Annual Meeting
- Place of Presentation
  Munchen, Germany
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病尿細管障害モデルにおいてTeneligliptinは腎障害分子機構　細胞外基質過剰産生プログラムを抑制する2016
- Author(s)
  高垣雄太, 高木晋, 加藤誠, 金崎啓造, 古家大祐
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Catechol-O-methyltransferase deficiency leads to hypersensitivity on the pressor response against angiotensin II2016
- Author(s)
  Norikazu Ueki, Keizo Kanasaki, Megumi Kanasaki, Satoru Takeda, Daisuke Koya
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] メタボリックシンドロームの病態生理学カテコール代謝異常とメタボリックシンドローム2016
- Author(s)
  金崎啓造
- Organizer
  第26回日本病態生理学会
- Place of Presentation
  金沢医科大学(石川県河北郡内灘)
- Year and Date
  2016-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 透析患者とエピジェネティクス糖尿病腎におけるmicroRNAの役割2016
- Author(s)
  金崎啓造
- Organizer
  第61回日本透析医学会年次学術総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-06-09
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] The Interaction between DPP-4 and Integrin beta1 Regulates the Signaling Responsible for Induction of the Endothelial to Mesenchymal Transition in Diabetic Kidney2015
- Author(s)
  KEIZO KANASAKI, SEN SHI, MEGUMI KANASAKI, DAISUKE KOYA
- Organizer
  Annual meeting, America Diabetes Association
- Place of Presentation
  Boston Convention Center (Boston, USA)
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Catechol-O-methyltransferase deficiency leads to hypersensitivity on the pressor response against angiotensin II2015
- Author(s)
  Norikazu Ueki, Satoru Takeda, Megumi Kanasaki, Daisuke Koya, Keizo Kanasaki
- Organizer
  ISSHP European Congress
- Place of Presentation
  Castle district of Budapest (Budapest, Hungary)
- Year and Date
  2015-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] アンチ・エイジング的な糖尿病トータルケア糖尿病腎の線維化を標的とした治療戦略　内皮細胞恒常性に注目して2015
- Author(s)
  金崎啓造
- Organizer
  日本抗加齢医学会総会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] DPP-4とintegrin β1の相互作用は糖尿病腎の線維化と内皮細胞間葉系分化を惹起する2015
- Author(s)
  金崎啓造, Shi Sen, 金崎めぐみ, 古家大祐
- Organizer
  日本糖尿病学会総会
- Place of Presentation
  海峡メッセ下関 (山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT不全がマウスにおいてangiotensin IIに対する昇圧感受性亢進を惹起する2015
- Author(s)
  植木典和, 竹田省, 金崎めぐみ, 古家大祐, 金崎啓造
- Organizer
  日本妊娠高血圧学会総会
- Place of Presentation
  北海道大学学術交流会館　（北海道札幌市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病合併症の疫学と最新の診断法について糖尿病腎症の疫学と診断　最近の話題2015
- Author(s)
  古家大祐, 北田宗弘, 金崎啓造
- Organizer
  糖尿病合併症学会
- Place of Presentation
  ウインク愛知 (愛知県名古屋市)
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病腎症治療の深化と展望腎fibrosisをターゲットとした糖尿病腎症の治療戦略2015
- Author(s)
  古家大祐, 金崎啓造, 北田宗弘
- Organizer
  日本糖尿病学会総会
- Place of Presentation
  海峡メッセ下関 (山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 内因性抗線維化ペプチドAcSDKPは糖尿病腎の線維化に対する経口治療薬になりうる2015
- Author(s)
  新田恭子, 永井貴子, 金崎めぐみ, 羽田勝計, 金崎啓造, 古家大祐
- Organizer
  日本糖尿病学会総会
- Place of Presentation
  海峡メッセ下関 (山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病腎線維化における内因性抗線維化ペプチドAcSDKPの意義とその作用機序における抗線維化microRNAクロストーク2015
- Author(s)
  永井貴子, Srivastava Swayam Prakash, 金崎啓造, 古家大祐
- Organizer
  糖尿病合併症学会
- Place of Presentation
  ウインク愛知 (愛知県名古屋市)
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 妊娠高血圧症候群に関する新知見 COMT不全と糖代謝異常2015
- Author(s)
  金崎啓造
- Organizer
  日本妊娠高血圧学会総会
- Place of Presentation
  北海道大学学術交流会館　（北海道札幌市）
- Year and Date
  2015-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Therapeutic Oral Administration of N-acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Histology and Function in Both Type 1 and Type 2 Diabetic Mice2015
- Author(s)
  KYOKO NITTA, SEN SHI, TAKAKO NAGAI, MEGUMI KANASAKI, MASAKAZU HANEDA, KEIZO KANASAKI, DAISUKE KOYA
- Organizer
  Annual meeting, America Diabetes Association
- Place of Presentation
  Boston Convention Center (Boston, USA)
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Combat kidney fibrosis in diabetes,2015
- Author(s)
  金崎啓造
- Organizer
  Symposium on“New Era of lipid and glycomedicine research”
- Place of Presentation
  高雄（台湾）
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 壊死性筋膜炎を伴った糖尿病性腎症の1症例2015
- Author(s)
  金崎啓造, 渡辺愛, 中川淳, 北田宗弘, 永井貴子, 伊藤弘樹, 津田真一, 小西一典, 西澤誠, 古家大祐
- Organizer
  日本腎臓学会西部学術大会
- Place of Presentation
  金沢歌劇座 (石川県金沢市）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] The Presence of the Anti-Fibrotic MicroRNA Crosstalk in the Effect of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline on Kidney Fibrosis in Diabetes2015
- Author(s)
  Keizo Kanasaki, Sen Shi, Megumi Kanasaki, Daisuke Koya
- Organizer
  Annual meeting, American Society of Nephrology
- Place of Presentation
  SanDiego Convention Center (SanDiego, USA)
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病腎における内皮細胞-間葉細胞分化(EndMT)を標的とした抗線維化治療戦略2014
- Author(s)
  金崎啓造
- Organizer
  慢性腎臓病研究と治療の次世代戦略　（京都大学シンポジウム）
- Place of Presentation
  京都大学芝蘭会館 (京都府、京都市)
- Year and Date
  2014-07-09
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT deficiency and its relevance2014
- Author(s)
  金崎啓造
- Organizer
  46th International Congress on Pathophysiology of Pregnancy
- Place of Presentation
  京王プラザホテル (東京都)
- Year and Date
  2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病性腎症教育講演2014
- Author(s)
  金崎啓造
- Organizer
  日本腎臓学会西部大会
- Place of Presentation
  神戸国際会議場(兵庫県、神戸市)
- Year and Date
  2014-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] 糖尿病における腎線維化とendothelial mesenchymal transition2014
- Author(s)
  金崎啓造
- Organizer
  第18回腎間質障害研究会
- Place of Presentation
  経団連会館(東京都)
- Year and Date
  2014-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Storkhead Box Protein1不全は胎盤でのレニンの過剰発現を惹起しマウスにおいて妊娠高血圧症候群の原因となる2013
- Author(s)
  金崎啓造
- Organizer
  腎と妊娠研究会
- Place of Presentation
  筑波（国際会議場）
- Data Source
  KAKENHI-PROJECT-24590189
[Presentation] COMT不全がもたらす妊娠高血圧腎症と糖代謝異常2013
- Author(s)
  金崎啓造
- Organizer
  妊娠高血圧学会
- Place of Presentation
  富山国際会議場、富山
- Year and Date
  2013-10-04
- Invited
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-methyltransferase and 2-Methoxyestradiol Deficiency is Associated With Hepatic Steatosis and Glucose Tolerance Defects2013
- Author(s)
  Keizo Kanasaki, Megumi Kanasaki, Daisuke Koya
- Organizer
  73th American Diabetes Association Annual Meeting
- Place of Presentation
  McCormick Place Convention Center, Shicago
- Year and Date
  2013-06-22
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 糖尿病性腎症に対する抗線維化を標的とした新規治療戦略2013
- Author(s)
  金崎啓造,古家大祐
- Organizer
  日本腎臓学会西部地方会
- Place of Presentation
  松山全日空ホテル、松山
- Year and Date
  2013-10-12
- Invited
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Linagliotin-Mediated DPP-4 Inhibition Cures Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition2013
- Author(s)
  Keizo Kanasaki, Takako Nagai, Megumi Kanasaki, Daisuke
- Organizer
  American Society of Nephrology, Annual Meeting
- Place of Presentation
  Georgia World Congress Center, Atlanta
- Year and Date
  2013-11-09
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-methyltransferase 不全は耐糖能異常・脂肪肝発症の病態において重要な役割を演じる2012
- Author(s)
  金崎啓造
- Organizer
  日本糖尿病学会総会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Preeclampsia and Metabolic Syndrome;Possible Shared Molecular Mechanism2012
- Author(s)
  金崎啓造
- Organizer
  BIT`s 1st International Congress of Gynaecology and Obsterics-2012（招待講演）
- Place of Presentation
  広州（国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-24590189
[Presentation] PlGFノックアウトマウスにおける妊娠中の生理的なsFlt1上昇は妊娠高血圧腎症様表現型を呈しない2012
- Author(s)
  金崎啓造
- Organizer
  本腎臓学会総会
- Place of Presentation
  横浜　（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590189
[Presentation] PlGFノックアウトマウスにおける妊娠中の生理的なsFlt1上昇は妊娠高血圧腎症様表現型を呈しない2012
- Author(s)
  金崎啓造
- Organizer
  日本腎臓学会総会
- Place of Presentation
  横浜 (パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-Methyltransferase Deficiency Is Associated with Abnormal Adiposity and Glucose Intolerance: Implication for a New Mechanism of Metabolic Syndrome2012
- Author(s)
  Keizo Kanasaki
- Organizer
  日本臨床分子医学会
- Place of Presentation
  京都　(みやこめっせ）
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-Methyltransferase Deficiency Is Associated with Abnormal Adiposity and Glucose Intolerance: Implication for a New Mechanism of Metabolic Syndrome2012
- Author(s)
  Keizo Kanasaki
- Organizer
  日本臨床分子医学会
- Place of Presentation
  京都　(みやこめっせ）
- Data Source
  KAKENHI-PROJECT-24590189
[Presentation] Catechol-o-methyltransferase 不全は耐糖能異常・脂肪肝発症の病態において重要な役割を演じる2012
- Author(s)
  金崎啓造
- Organizer
  日本糖尿病学会総会
- Place of Presentation
  横浜(パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590189
[Presentation] Role of 2-ME, PlGF, and Stox1 Transcriprional Factor in Preeclampsia2011
- Author(s)
  金崎啓造
- Organizer
  World Congress of Nephrology(招待講演)
- Place of Presentation
  Vancouver convention center
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Identification of Stox1 Transcription Factor as a Specific Repressor of Placental Renin and its Deficiency Leads to Vascular Defects and Gestational Hypertension2011
- Author(s)
  金崎啓造
- Organizer
  Annual meeting, American Society of Nephrology
- Place of Presentation
  Philadelphia convention center
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Natural history of Diabetic Nephropathy in Japan2011
- Author(s)
  金崎啓造
- Organizer
  Asian Association of Study of Diabetes(招待講演)
- Place of Presentation
  Beijing convention center
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-Methyltransferase Deficiency is associated with Abnormal Adiposity and Glucose Intolerance: Implication for a New Mechanism of Metabolic Syndrome2011
- Author(s)
  金崎啓造
- Organizer
  Annual meeting, American Diabetic Association
- Place of Presentation
  San Diego convention center
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Storkhead Box Protein1不全は胎盤でのレニンの過剰発現を惹起しマウスにおいて妊娠高血圧症候群の原因となる2011
- Author(s)
  金崎啓造
- Organizer
  日本腎臓学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Catechol-o-methyltransferase 不全は耐糖能異常・脂肪肝発症の病態において重要な役割を演じる2011
- Author(s)
  金崎啓造
- Organizer
  分子糖尿病研究会
- Place of Presentation
  くまもと県民交流館パレア
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化ペプチドAcSDKPによるマウス糖尿病性腎症にたいする治療効果は、miRNA let-7 family cluster発現レベルと相関する
- Author(s)
  金崎啓造、永井貴子、金崎めぐみ、古家大祐
- Organizer
  日本糖尿病学会学術総会
- Place of Presentation
  日航ホテル, 熊本
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 糖尿病性腎症に対する抗線維化を標的とした新規治療法
- Author(s)
  金崎啓造、古家大祐
- Organizer
  日本腎臓学会西部地方会
- Place of Presentation
  松山全日空ホテル, 松山
- Invited
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化ペプチドAcSDKPは FGF受容体発現とmiRNA　let-7の正常化を介して糖尿病腎の線維化を抑制する
- Author(s)
  永井貴子、金崎めぐみ、金崎啓造、古家大祐
- Organizer
  糖尿病性腎症研究会
- Place of Presentation
  東京ガーデンパレス, 東京
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Linagliptin-Mediated DPP-4 Inhibition Cures Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition
- Author(s)
  Keizo Kanasaki, Takako Nagai, Megumi Kanasaki, Daisuke Koya
- Organizer
  American Society of Nephrology, annual meeting
- Place of Presentation
  Georgia World Congress Center, Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Preeclampsia and Metabolic Syndrome;Possible Shared Molecular Mechanisms
- Author(s)
  金崎啓造
- Organizer
  BIT`s 1st International Congress of Gynaecology and Obsterics-2012
- Place of Presentation
  広州 (国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] COMT不全と糖代謝異常
- Author(s)
  金崎啓造
- Organizer
  日本妊娠高血圧学会
- Place of Presentation
  北海道大学学術交流会館 (北海道、札幌市）
- Year and Date
  2015-09-11 – 2015-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Catechol-o-methyltransferase and 2-Methoxyestradiol Deficiency is Associated With Hepatic Steatosis and Glucose Rolerance Defects
- Author(s)
  Keizo Kanasaki, Megumi Kanasaki, Daisuke Koya
- Organizer
  American Diabetes Association annual meeting
- Place of Presentation
  McCormick Place Convention Center, Chicago,USA
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] COMT不全は耐糖能異常に関連する
- Author(s)
  植木典和, 金崎めぐみ、竹田省、古家大祐、金崎啓造
- Organizer
  腎と妊娠研究会
- Place of Presentation
  川越プリンスホテル, 川越
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化分子AcSDKPはEndMTを抑制し糖尿病性腎症-腎線維化に対して有効な治療戦略となる
- Author(s)
  永井貴子、金崎めぐみ、金崎啓造、古家大祐
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム, 東京
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Linagliptinを用いたDipeptidyl Peptidase-4阻害による糖尿病マウス腎線維化に対する治療効果とその分子機構
- Author(s)
  金崎啓造
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪国際会議場 (大阪府、大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Linagliptin-mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-induced Diabetic Mice via Restoring microRNA29s
- Author(s)
  金崎啓造
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  Sanfrancisco （アメリカ）
- Year and Date
  2014-06-12 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] COMT不全がもたらす妊娠高血圧腎症と糖代謝異常
- Author(s)
  金崎啓造
- Organizer
  妊娠高血圧学会
- Place of Presentation
  富山国際会議場, 富山
- Invited
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化分子AcSDKPによる糖尿病性腎症治療効果とその分子機構におけるmiRNAの意義
- Author(s)
  永井　貴子，金崎　めぐみ，金崎　啓造，古家　大祐
- Organizer
  分子腎臓研究会
- Place of Presentation
  メルパルク京都, 京都
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 糖尿病腎の線維化を標的とした治療戦略：内皮細胞恒常性に注目して
- Author(s)
  金崎啓造
- Organizer
  日本抗加齢学会
- Place of Presentation
  福岡国際会議場 (福岡県、福岡市)
- Year and Date
  2015-05-29 – 2015-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] The interaction between DPP-4 and integrin β1 regulates the signaling responsible for induction of the endothelial to mesenchymal transition in diabetic kidney
- Author(s)
  金崎啓造
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  Boston　(アメリカ）
- Year and Date
  2015-06-04 – 2015-06-10
- Data Source
  KAKENHI-PROJECT-26460403
[Presentation] Storkhead Box Protein1不全は胎盤でのレニンの過剰発現を惹起しマウスにおいて妊娠高血圧症候群の原因となる
- Author(s)
  金崎啓造
- Organizer
  腎と妊娠研究会
- Place of Presentation
  筑波（国際会議場）
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Endogenous anti-fibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline restored kidney fibrosis in association with microRNA-let-7 cluster alterations
- Author(s)
  Keizo Kanasaki, Takako Nagai, Megumi Kanasaki, Daisuke Koya
- Organizer
  World Congress of Nephrology WCN 2013
- Place of Presentation
  Hon Kong Convention Center,Hong Kong,
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化ペプチドAcSDKPを用いた糖尿病マウス腎線維化に対する治療効果と miRNA let-7 familyの相関
- Author(s)
  金崎啓造、永井貴子、金崎めぐみ、古家大祐
- Organizer
  日本糖尿病合併症学会
- Place of Presentation
  旭川グランドホテル, 旭川
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 内因性抗線維化分子AcSDKPは EndMTを抑制し，抗EndMT作用を示すmiRNA let-7 familyの発現レベル改善を認めた
- Author(s)
  永井貴子、金崎めぐみ、金崎啓造、古家大祐
- Organizer
  Front J　研究会
- Place of Presentation
  経団連会館, 東京
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] Anti-fibrotic peptide AcSDKP restores diabetes-suppressed microRNA-let-7 cluster and exhibits therapeutic effect on kidney fibrosis in diabetes
- Author(s)
  Keizo Kanasaki, Takako Nagai, Swayam Prakash Srivastava, Megumi Kanasaki, Daisuke Koya
- Organizer
  EASD2013 (european association for the study of diabetes)
- Place of Presentation
  The Fira de Barcelona’s Gran Via exhibition centre, Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] 高ケト原性アミノ酸食による脂肪肝抑制効果は肝臓でのオートファジー誘導と関係する
- Author(s)
  金崎めぐみ、Ling Xu、北田宗弘、長尾健児、神通寛子、野口泰志、金崎啓造、古家大祐
- Organizer
  日本糖尿病学会学術総会
- Place of Presentation
  日航ホテル, 熊本
- Data Source
  KAKENHI-PROJECT-23790381
[Presentation] DPP-4とintegrin β1の相互作用は糖尿病腎の線維化と内皮細胞-間葉系分化を惹起する
- Author(s)
  金崎啓造
- Organizer
  日本糖尿病学会
- Place of Presentation
  海峡メッセ下関 (山口県、下関市)
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-26460403

1. KOYA Daisuke (70242980)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. KITADA Munehiro (40434469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. KANASAKI Megumi (50599355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 82 results
4. 飯島洋 (30465281)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 高垣雄太 (50759123)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 川北恵美 (70835884)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. KIM Hyoh (10612377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. NAGAI Takako (90625443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 外山雄大 (60880507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 矢本琢真 (60931227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小林弘典 (70397868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 槇野裕文 (90896052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 松崎桂一 (20229454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 齋藤弘明 (30385976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高宮知子 (50513917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小菅康弘 (70383726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 石垣靖人 (20232275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 林義大 (60868636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 太田美和 (00548620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平井順子 (20931207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YAMAMOTO Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. MORITA Yoshikata

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. MIMA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. KUWAGATA Shogo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 安田真子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 安藤昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 久米真司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 佐藤杏奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 池田崇之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 吉冨泰央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 小倉慶雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 水沼有威子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanasaki Keizo 金崎 啓造

KANASAKI Keizo 金崎 啓造

Research Projects

Research Products

Co-Researchers

スプライソソーム機能異常に着目した糖尿病関連腎臓病に対する治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

微量栄養素欠乏および補充が糖尿病性腎症の進展とサルコペニアに与える影響の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Potency of enhancer compounds in the filed of renal and cardiovascular diseases.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

サルコペニア合併糖尿病性腎臓病における負のスパイラルを標的とした治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interaction between genetic COMT deficiency and Mg defects induced diseases: mechanisms and therapeutic strategyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Endothelial autophagy deficiency induces interleukin 6-dependent endothelial mesenchymal transition and organ fibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of the molecular mechanisms in COMT-deficiency-induced health problemsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Alteration in nutrient sensing and metabolic diseases

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

New therapeutic strategy for diabetic nephropathy via autophagy regulation

Principal Investigator

Project Period (FY)

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Research Institution

Understanding of the metabolic abnormalities induced by COMT inhibitor administration

Principal Investigator

Project Period (FY)

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Research Institution

Development of control means of renal fibrosis focused on endogenous anti-fibrotic molecule

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Investigation for the physiological and pathological significance of the interaction between COMT deficiency and homocysteinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Pharma Medica: 【糖尿病性腎症の克服を目指して～up to date～】 SGLT2阻害薬と腎機能2016

Author(s)

Publisher

Kanasaki Keizo 金崎啓造

KANASAKI Keizo 金崎啓造

[Book] 【糖尿病を診る　ポケット検査事典】　合併症　腎症および水・電解質代謝尿酸(尿酸クリアランスを含む)2016

[Book] 糖尿病ケア (【患者さんがみるみる変わる!ダウンロードでそのまま使える!魔法の糖尿病患者説明シート50+α】 (第2章)糖尿病のリスク・合併症の患者説明シート16　透析になったら何がどうなる?)2016

[Book] Diabetes Update: SGLT・レッスン　SGLT2阻害薬が腎に及ぼす影響の可能性2016

[Book] 糖尿病：腎機能保護の観点からの有用性2016

[Book] カレントセラピー: 糖尿病性腎症の治療　血糖コントロールの意義と新しい血糖降下薬への期待2016

[Book] 最新医学 (【インクレチン薬による糖尿病治療の革新-基礎と臨床の架け橋-】基礎研究　インクレチンの腎臓への作用)2016

[Book] 【糖尿病を診る　ポケット検査事典】　合併症　腎症および水・電解質代謝電解質2016

[Book] Annual Review腎臓 (尿細管・間質障害腎線維化と内皮細胞間葉細胞分化)2016

[Book] 成人病と生活習慣病: 【腎機能を悪化させない日常診療】糖尿病における腎機能のみかたと対策2016

[Book] 糖尿病ケア:【透析導入を防ぐ　図解でわかる!糖尿病腎症の病態生理と患者指導】病態生理からセルフケアまで糖尿病腎症のすべて　腎臓を悪くしないための薬はあるの?2016

[Book] 糖尿病診療マスター　（【糖尿病は回復するだろうか Part 2-腎障害は寛解するか】腎障害が止めがたいタイプとは?）2015