Katada Kazuhiro 堅田和弘

Researcher Number	60593910
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help	2023: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2021 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2020: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2013 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2015: 京都府立医科大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 粘膜関連細菌叢 / 生活習慣病 / 腸管バリア / 腸内細菌叢 / 腸管粘膜上皮機能 / 粘膜バリア Except Principal Investigator Heme oxygenase-1 / マクロファージ / 一酸化炭素 / ヘムオキシゲナーゼ … More / 炎症性腸疾患 / Heme oxygenase / 腸内環境 / 一酸化炭 / 大腸潰瘍 / 皮膚潰瘍 / 腸内細菌叢 / Paraprevotella / 潰瘍性大腸炎 / Bach1 / Heme Oxygenase-1 / リンパ球分化 / Th17リンパ球分化 / ナイーブCD4+ T細胞 / heme oxygenase-1 / 腸管炎症 / リンパ球 Less

Development of novel treatment for lifestyle-related diseases targeting mucosa-associated microbiota and mucosal barrierPrincipal Investigator
- Principal Investigator
  
  堅田和弘
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Heme oxygenase/carbon monoxide-mediated intestinal modulation for the development of gas molecule drugs
- Principal Investigator
  
  Tomohisa Takagi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Therapeutic application of lifestyle-related diseases targeting mucosa-associated microbiota and mucosal barrierPrincipal Investigator
- Principal Investigator
  
  Katada Kazuhiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
The development of drug delivery system of carbon monoxide for inflammatory bowel disease
- Principal Investigator
  
  Takagi Tomohisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
The role of Heme oxygenate-1 and carbon monoxide in the intestinal inflammation
- Principal Investigator
  
  Tomohisa Takagi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2024 2023 2022 2021 2019 2018 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] Clinical Background Factors as Predictors of the Efficacy of 5-Aminosalicylic Acid Suppositories in Patients with Ulcerative Colitis2023
- Author(s)
  Uchiyama Kazuhiko、Takagi Tomohisa、Mizushima Katsura、Asaeda Kohei、Kubota-Kajiwara Mariko、Sugaya Takeshi、Kashiwagi Saori、Minagawa Yuki、Hotta Yuma、Tanaka Makoto、Inoue Ken、Katada Kazuhiro、Kamada Kazuhiro、Ishikawa Takeshi、Yasuda Hiroaki、Konishi Hideyuki、Kishimoto Mitsuo、Naito Yuji、Itoh Yoshito
- Journal Title
  
  Inflammatory Intestinal Diseases
  
  Volume: 8 Issue: 2 Pages: 84-90
- DOI
  10.1159/000533543
- Data Source
  KAKENHI-PROJECT-20K11513
[Journal Article] Astaxanthin attenuated the stress-induced intestinal motility disorder via altering the gut microbiota2022
- Author(s)
  Yasuda Ritsu、Kamada Kazuhiro、Murakami Takaaki、Inoue Ryo、Mizushima Katsura、Hirose Ryohei、Inoue Ken、Dohi Osamu、Yoshida Naohisa、Katada Kazuhiro、Uchiyama Kazuhiko、Handa Osamu、Ishikawa Takeshi、Takagi Tomohisa、Konishi Hideyuki、Naito Yuji、Itoh Yoshito
- Journal Title
  
  International Journal for Vitamin and Nutrition Research
  
  Volume: - Issue: 5 Pages: 427-437
- DOI
  10.1024/0300-9831/a000756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11513, KAKENHI-PROJECT-19K08376
[Journal Article] Role and Potential Mechanism of Heme Oxygenase-1 in Intestinal Ischemia-Reperfusion Injury.2022
- Author(s)
  Katada K, Takagi T, Iida T, Ueda T, Mizushima K, Fukui A, Okayama T, Kamada K, Uchiyama K, Ishikawa T, Naito Y, Itoh Y.
- Journal Title
  
  Antioxidants.
  
  Volume: 11 Issue: 3 Pages: 559-559
- DOI
  10.3390/antiox11030559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08292, KAKENHI-PROJECT-20K08363, KAKENHI-PROJECT-20K11513
[Journal Article] Partially hydrolyzed guar gum attenuates non-alcoholic fatty liver disease in mice through the gut-liver axis2021
- Author(s)
  Takayama Shun、Katada Kazuhiro、Takagi Tomohisa、Iida Takaya、Ueda Tomohiro、Mizushima Katsura、Higashimura Yasuki、Morita Mayuko、Okayama Tetsuya、Kamada Kazuhiro、Uchiyama Kazuhiko、Handa Osamu、Ishikawa Takeshi、Yasukawa Zenta、Okubo Tsutomu、Itoh Yoshito、Naito Yuji
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 27 Issue: 18 Pages: 2160-2176
- DOI
  10.3748/wjg.v27.i18.2160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11513
[Journal Article] Rectal administration of carbon monoxide inhibits the development of intestinal inflammation and promotes intestinal wound healing via the activation of the Rho-kinase pathway in rats.2021
- Author(s)
  Takagi T, Naito Y, Higashimura Y, Uchiyama K, Okayama T, Mizushima K, Katada K, Kamada K, Ishikawa T, Itoh Y.
- Journal Title
  
  Nitric Oxide.
  
  Volume: 107 Pages: 19-30
- DOI
  10.1016/j.niox.2020.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08292, KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06224
[Journal Article] Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice2019
- Author(s)
  Takagi T, Homma T, Fujii J, Shirasawa N, Yoriki H, Hotta Y, Higashimura Y, Mizushima K, Hirai Y, Katada K, Uchiyama K, Naito Y, Itoh Y.
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 134 Pages: 153-164
- DOI
  10.1016/j.freeradbiomed.2018.12.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05475, KAKENHI-PROJECT-18K06948, KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-18K06224
[Journal Article] Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4(+) T cells.2018
- Author(s)
  Tanaka M, Takagi T, Naito Y, Uchiyama K, Hotta Y, Toyokawa Y, Ushiroda C, Hirai Y, Aoi W, Higashimura Y, Mizushima K, Okayama T, Katada K, Kamada K, Ishikawa T, Handa O, Itoh Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 33 Issue: 3 Pages: 671-680
- DOI
  10.1111/jgh.13842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09322, KAKENHI-PROJECT-16H05289, KAKENHI-PROJECT-16K16281, KAKENHI-PROJECT-17H02176
[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018
- Author(s)
  Takagi T, Naito Y, Mizushima K, Hirai Y, Harusato A, Okayama T, Katada K, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.
- Journal Title
  
  J Clin Biochem Nutr.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09322
[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018
- Author(s)
  Takagi Tomohisa、Naito Yuji、Mizushima Katsura、Hirai Yasuko、Harusato Akihito、Okayama Tetsuya、Katada Kazhuhiro、Kamada Kazuhiro、Uchiyama Kazuhiko、Handa Osamu、Ishikawa Takeshi、Itoh Yoshito
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 63 Issue: 3 Pages: 169-174
- DOI
  10.3164/jcbn.17-133
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15128, KAKENHI-PROJECT-16K09322
[Journal Article] Multiple targets of carbon monoxide gas in the intestinal inflammation.2016
- Author(s)
  Naito Y, Takagi T, Uchiyama K, Katada K, Yoshikawa T.
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 595 Pages: 147-52
- DOI
  10.1016/j.abb.2015.06.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460959, KAKENHI-PROJECT-16K09322
[Journal Article] Therapeutic roles of carbon monoxide in intestinal ischemia-reperfusion injury.2015
- Author(s)
  Katada K, Takagi T, Uchiyama K, Naito Y.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 30 Issue: S1 Pages: 46-52
- DOI
  10.1111/jgh.12742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460959
[Journal Article] BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-12013
- Author(s)
  Harusato, A. Naito, Y. Takagi, T. Uchiyama, K. Mizushima, K. Hirai, Y. Higashimura, Y. Katada, K. Handa, O. Ishikawa, T. Yagi, N. Kokura, S. Ichikawa, H. Muto, A. Igarashi, K. Yoshikawa, T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 19 Issue: 4 Pages: 740-753
- DOI
  10.1097/mib.0b013e3182802968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590705, KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-23790322, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460959, KAKENHI-PUBLICLY-23117702
[Journal Article] Hemin ameliorates indomethacin-induced small intestinal injury in mice through the induction of heme oxygenase-12013
- Author(s)
  Hiroyuki Yoriki
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: Apr;28(4) Issue: 4 Pages: 632-638
- DOI
  10.1111/jgh.12074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-25460959
[Presentation] Role of ferroptosis in intestinal ischemia-reperfusion injury2024
- Author(s)
  堅田和弘、髙木智久、尾松達司、鎌田和浩、内山和彦、内藤裕二
- Organizer
  第49回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-23K10804
[Presentation] Role of ferroptosis in intestinal ischemia-reperfusion injury2024
- Author(s)
  堅田和弘、髙木智久、尾松達司、鎌田和浩、内山和彦、内藤裕二
- Organizer
  第49回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K11513
[Presentation] 大腸癌進行予測におけるヘムオキシゲナーゼ-1の有用性の検討2023
- Author(s)
  堅田和弘、髙木智久、高山峻、水島かつら、平井泰子、菅谷武史、福居顕文、岡山哲也、内山和彦、内藤裕二
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K11513
[Presentation] Role and potential mechanism of action of heme oxygenase-1 in intestinal ischemia-reperfusion injury2023
- Author(s)
  Kazuhiro Katada, Tomohisa Takagi, Kazuhiro Kamada, Kazuhiko Uchiyama, Yuji Naito
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K11513
[Presentation] 新規治療分子としてのCOの可能性～微小循環研究の知見から～．2022
- Author(s)
  185髙木智久、内山和彦、堅田和弘、内藤裕二．
- Organizer
  第47回日本微小循環学会総会. シンポジウム1「歯科、消化器、微小循環研究の新展開」
- Data Source
  KAKENHI-PROJECT-20K08292
[Presentation] The role and potential mechanisms of heme oxygenase-1 on ischemia/reperfusion-challenged intestinal injury in mice2021
- Author(s)
  Kazuhiro Katada, Tomohisa Takagi, Kazuhiro Kamda, Yuji Naito
- Organizer
  第46回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K11513
[Presentation] Heme oxygenase-1/Carbon monoxide系による腸管免疫制御機構の解明
- Author(s)
  髙木智久、内藤裕二、福田　亘、堅田和弘、内山和彦、半田　修、伊藤義人
- Organizer
  第10回日本消化管学会総会学術集会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-25460959

1. Tomohisa Takagi (70405257)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
2. Naito Yuji (00305575)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 内山和彦 (50298428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. Mizushima Katsura

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 伊藤友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 東村泰希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Katada Kazuhiro 堅田 和弘

Research Projects

Research Products

Co-Researchers

Development of novel treatment for lifestyle-related diseases targeting mucosa-associated microbiota and mucosal barrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Heme oxygenase/carbon monoxide-mediated intestinal modulation for the development of gas molecule drugs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic application of lifestyle-related diseases targeting mucosa-associated microbiota and mucosal barrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of drug delivery system of carbon monoxide for inflammatory bowel disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Heme oxygenate-1 and carbon monoxide in the intestinal inflammation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinical Background Factors as Predictors of the Efficacy of 5-Aminosalicylic Acid Suppositories in Patients with Ulcerative Colitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Astaxanthin attenuated the stress-induced intestinal motility disorder via altering the gut microbiota2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role and Potential Mechanism of Heme Oxygenase-1 in Intestinal Ischemia-Reperfusion Injury.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Partially hydrolyzed guar gum attenuates non-alcoholic fatty liver disease in mice through the gut-liver axis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rectal administration of carbon monoxide inhibits the development of intestinal inflammation and promotes intestinal wound healing via the activation of the Rho-kinase pathway in rats.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated ER stress exacerbates dextran sulfate sodium-induced colitis in PRDX4-knockout mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Secreted protein acidic and rich in cysteine functions in colitis via IL17A regulation in mucosal CD4(+) T cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018

Author(s)

Journal Title

Data Source

[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

Katada Kazuhiro 堅田和弘