Iwagami Yoshifumi 岩上佳史

… Alternative Names

IWAGAMI Yoshifumi 岩上佳史

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Researcher Number	60597441
Other IDs
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院医学系研究科, 招へい教員 2022 – 2023: 大阪大学, 大学院医学系研究科, 助教 2019 – 2020: 大阪大学, 医学系研究科, 助教 2018 – 2019: 大阪大学, 医学系研究科, 特任助教(常勤) 2017: 大阪大学, 医学部附属病院, 医員 2012 – 2013: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 55020:Digestive surgery-related / General surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery
Keywords	Principal Investigator myokine / サルコペニア / 癌微小環境 / 骨格筋 / 膵癌 / cMet / 治療抵抗性 / 術前治療 / 膵がん / インスリン … More / Direct Reprogramming / Ngn3 / PDX-1 / MafA / ADSC … More Except Principal Investigator グルタミナーゼ1 / 老化癌細胞 / グルタミナーゼ１ / 老化細胞 / GLS1 / 老化細胞除去(senolytics) / 細胞老化随伴分泌現象(SASP因子) / グルタミナーゼ1(GLS1) / グルタミン代謝 / 細胞老化 / 膵癌 / 癌周囲環境細胞 / 癌微小環境構成細胞 / 浸潤 / 癌 / ドラッグ・リポジショニング / 上皮間葉転換 / エピゲノム / c-Met / 癌幹細胞 / 放射線耐性 / 抗癌剤耐性 Less

Interaction between skeletal muscle and cancer microenvironment in pancreatic cancer and its application to therapy to improve prognosisPrincipal Investigator
- Principal Investigator
  
  Iwagami Yoshifumi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
Crosstalk of tumor microenvironment during invasion process in hepato-biliary pancreatic cancer
- Principal Investigator
  
  Kobayashi Shogo
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Overcoming treatment resistance by removal senescent cancer cells targeting glutamine metabolism in pancreatic ductal adenocarcinoma
- Principal Investigator
  
  Oyama Keisuke
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
移植・再生医療に向けた肝・膵組織の三次元立体構築
- Principal Investigator
  
  浅岡忠史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
Evaluation of the resistant acquisition mechanisms in the pancreatic cancer with preoperative treatmentPrincipal Investigator
- Principal Investigator
  
  Iwagami Yoshifumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Elucidation of drug-resistance induction mechanism and construction of the new therapy targeting epigenome change
- Principal Investigator
  
  Eguchi Hidetoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Instruction of the insulin-producing cell by Direct ReprogrammingPrincipal Investigator
- Principal Investigator
  
  IWAGAMI Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University

All 2024 2023 2022 2020 2019 2017

All Journal Article Presentation

[Journal Article] The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma2024
- Author(s)
  Ito Yoshiro、Yamada Daisaku、Kobayashi Shogo、Sasaki Kazuki、Iwagami Yoshifumi、Tomimaru Yoshito、Asaoka Tadafumi、Noda Takehiro、Takahashi Hidenori、Shimizu Junzo、Doki Yuichiro、Eguchi Hidetoshi
- Journal Title
  
  Cancer Letters
  
  Volume: 595 Pages: 216997-216997
- DOI
  10.1016/j.canlet.2024.216997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08774, KAKENHI-PROJECT-22K08870
[Journal Article] 切除可能境界症例に対する術前治療は標準化されるか2024
- Author(s)
  小林省吾、山田大作、野田剛広、佐々木一樹、岩上佳史、富丸慶人、高橋秀典、土岐祐一郎、江口英利
- Journal Title
  
  胆と膵
  
  Volume: 45 Pages: 627-632
- Data Source
  KAKENHI-PROJECT-22K08774
[Journal Article] Skeletal Muscle-Derived Irisin Enhances Gemcitabine Sensitivity and Suppresses Migration Ability in Pancreatic Ductal Adenocarcinoma2024
- Author(s)
  Sugimoto Tomoki、Iwagami Yoshifumi、Kobayashi Shogo、Yamanaka Chihiro、Sasaki Kazuki、Yamada Daisaku、Tomimaru Yoshito、Asaoka Tadafumi、Noda Takehiro、Takahashi Hidenori、Shimizu Junzo、Doki Yuichiro、Eguchi Hidetoshi
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 6 Issue: 6 Pages: 3718-3736
- DOI
  10.1245/s10434-024-15118-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07169
[Journal Article] Removal of gemcitabine‐induced senescent cancer cells by targeting glutaminase1 improves the therapeutic effect in pancreatic ductal adenocarcinoma2023
- Author(s)
  Oyama Keisuke、Iwagami Yoshifumi、Kobayashi Shogo、Sasaki Kazuki、Yamada Daisaku、Tomimaru Yoshito、Noda Takehiro、Asaoka Tadafumi、Takahashi Hidenori、Tanemura Masahiro、Doki Yuichiro、Eguchi Hidetoshi
- Journal Title
  
  International Journal of Cancer
  
  Volume: 154 Issue: 5 Pages: 912-925
- DOI
  10.1002/ijc.34725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08845
[Journal Article] Prognostic value of functional SMAD4 localization in extrahepatic bile duct cancer2022
- Author(s)
  Takayama H, Kobayashi S, Gotoh K, Sasaki K, Iwagami Y, Yamada D, Tomimaru Y, Akita H, Asaoka T, Noda T, Wada H, Takahashi H, Tanemura M, Doki Y, Eguchi H.
- Journal Title
  
  World J Surg Oncol.
  
  Volume: 20 Pages: 291-291
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08774
[Journal Article] Preoperative FDG-Positive Lymph Nodes Predict the Postoperative Prognosis in Resectable Biliary Tract Cancers2022
- Author(s)
  Kubo M, Kobayashi S, Gotoh K, Takayama H, Iwagami Y, Yamada D, Tomimaru Y, Akita H, Noda T, Kato H, Shimosegawa E, Doki Y, Eguchi H.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 29 Pages: 935-935
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08774
[Journal Article] ACAT-1-Regulated Cholesteryl Ester Accumulation Modulates Gemcitabine Resistance in Biliary Tract Cancer2022
- Author(s)
  Ueno G, Iwagami Y, Kobayashi S, Mitsufuji S, Yamada D, Tomimaru Y, Akita H, Asaoka T, Noda T, Gotoh K, Mori M, Doki Y, Eguchi H.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 29 Pages: 2899-2899
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08774
[Journal Article] Endogenous CXCL9 affects prognosis by regulating tumor-infiltrating NK cells in intrahepatic cholangiocarcinoma2020
- Author(s)
  Fukuda Y, Asaoka T, Eguchi H, Yokota Y, Kubo M1, Kinoshita M, Urakawa S, Iwagami Y, Tomimaru Y, Akita H, Noda T, Gotoh K, Kobayashi S, Hirata M, Wada H, Mori M, Doki Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 2 Pages: 323-333
- DOI
  10.1111/cas.14267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03729, KAKENHI-PROJECT-17K10696
[Journal Article] A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma2019
- Author(s)
  Matsushita Katsunori、Konno Masamitsu、Eguchi Hidetoshi、Koseki Jun、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi、Obika Satoshi
- Journal Title
  
  ChemMedChem
  
  Volume: 14 Issue: 15 Pages: 1384-1391
- DOI
  10.1002/cmdc.201900324
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08704, KAKENHI-PROJECT-19K07688, KAKENHI-PROJECT-19K09172, KAKENHI-PROJECT-19K22658, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-17K10696, KAKENHI-PROJECT-18K16356
[Journal Article] Impact of CD36 on Chemoresistance in Pancreatic Ductal Adenocarcinoma2019
- Author(s)
  Kubo Masahiko、Gotoh Kunihito、Eguchi Hidetoshi、Kobayashi Shogo、Iwagami Yoshifumi、Tomimaru Yoshito、Akita Hirofumi、Asaoka Tadafumi、Noda Takehiro、Takeda Yutaka、Tanemura Masahiro、Mori Masaki、Doki Yuichiro
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 27 Issue: 2 Pages: 610-619
- DOI
  10.1245/s10434-019-07927-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10696
[Journal Article] Fatty Acid-Mediated Stromal Reprogramming of Pancreatic Stellate Cells Induces Inflammation and Fibrosis That Fuels Pancreatic Cancer.2017
- Author(s)
  Hata T, Kawamoto K, Eguchi H, Kamada Y, Takamatsu S, Maekawa T, Nagaoka S, Yamada D, Iwagami Y, Asaoka T, Noda T, Wada H, Gotoh K, Masamune A, Miyoshi E, Mori M, Doki Y.
- Journal Title
  
  Pancreas
  
  Volume: 46 Issue: 10 Pages: 1259-1266
- DOI
  10.1097/mpa.0000000000000943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10696, KAKENHI-PROJECT-15H04810, KAKENHI-PROJECT-16H05226, KAKENHI-PROJECT-16K15428
[Presentation] ロボット支援下膵頭十二指腸切除における工夫2024
- Author(s)
  小林省吾、野田剛広、富丸慶人、占部翔一朗、佐々木一樹、長谷川慎一郎、山田大作、岩上佳史、高橋秀典、中島清一、土岐祐一郎、江口英利
- Organizer
  第86回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08774
[Presentation] 進行胆嚢癌に対する切除戦略と薬物療法2024
- Author(s)
  小林省吾、山田大作、秋田裕史、佐々木一樹、長谷川慎一郎、富丸慶人、野田剛広、岩上佳史、高橋秀典、土岐祐一郎、江口英利
- Organizer
  第86回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08774
[Presentation] ロボット支援下肝胆膵手術における工夫と膵頭十二指腸切除2024
- Author(s)
  小林省吾、野田剛広、富丸慶人、占部翔一朗、佐々木一樹、長谷川慎一郎、山田大作、岩上佳史、高橋秀典、中島清一、土岐祐一郎、江口英利
- Organizer
  第37回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08774
[Presentation] 浸潤性膵管癌におけるグルタミナーゼ1を標的とした治療誘導性老化癌細胞除去による治療効果の向上2023
- Author(s)
  小山啓介, 岩上佳史, 小林省吾, 佐々木一樹, 山田大作, 富丸慶人, 野田剛広, 高橋秀典, 土岐祐一郎, 江口英利
- Organizer
  第123回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08845
[Presentation] Overcoming treatment resistance by removal of senescent cancer cells targeting glutaminase1 in pancreatic cancer2022
- Author(s)
  Keisuke Oyama, Yoshifumi Iwagami, Shogo Kobayashi, Kazuki Sasaki, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Yuichiro Doki, Hidetoshi Eguchi
- Organizer
  The 81st Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-22K08845
[Presentation] Overcoming treatment resistance by removal senescent cancer cells targeting glutamine metabolism in pancreatic ductal adenocarcinoma2022
- Author(s)
  Keisuke Oyama, Yoshifumi Iwagami, Shogo Kobayashi, Kazuki Sasaki, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Shin Nakahira, Hidenori Takahashi, Yuichiro Doki, Hidetoshi Eguchi
- Organizer
  2nd International Congress of Asian Oncology Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08845
[Presentation] 膵癌におけるグルタミナーゼ1を標的とした治療誘導性老化癌細胞除去による治療効果の向上2022
- Author(s)
  小山啓介、岩上佳史、小林省吾、佐々木一樹、山田大作、富丸慶人、野田剛広、高橋秀典、土岐祐一郎、江口英利
- Organizer
  第42回日本分子腫瘍マーカー研究会
- Data Source
  KAKENHI-PROJECT-22K08845
[Presentation] 脈管浸潤陽性膵癌の術前療法は化学療法をすべきか、化学放射線療法をすべきか2017
- Author(s)
  江口英利, 後藤邦仁, 和田浩志, 浅岡忠史, 野田剛広, 山田大作, 岩上佳史, 川本弘一, 森正樹, 土岐祐一郎
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10696

1. Kobayashi Shogo (30452436)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. Eguchi Hidetoshi (90542118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. Oyama Keisuke (90804071)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 後藤邦仁 (10362716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 山田大作 (60571396)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. 野田剛広 (50528594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. 和田浩志 (00572554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 浅岡忠史 (60528470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 杉本智樹 (20882244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 高橋秀典 (90601120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 富丸慶人 (70528570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
12. 佐々木一樹 (20745442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. HIDESHI Ishii

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 佐藤太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 小関準

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 和田尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iwagami Yoshifumi 岩上 佳史

IWAGAMI Yoshifumi 岩上 佳史

Research Projects

Research Products

Co-Researchers

Interaction between skeletal muscle and cancer microenvironment in pancreatic cancer and its application to therapy to improve prognosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Crosstalk of tumor microenvironment during invasion process in hepato-biliary pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Overcoming treatment resistance by removal senescent cancer cells targeting glutamine metabolism in pancreatic ductal adenocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

移植・再生医療に向けた肝・膵組織の三次元立体構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of the resistant acquisition mechanisms in the pancreatic cancer with preoperative treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of drug-resistance induction mechanism and construction of the new therapy targeting epigenome change

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Instruction of the insulin-producing cell by Direct ReprogrammingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 切除可能境界症例に対する術前治療は標準化されるか2024

Author(s)

Journal Title

Data Source

[Journal Article] Skeletal Muscle-Derived Irisin Enhances Gemcitabine Sensitivity and Suppresses Migration Ability in Pancreatic Ductal Adenocarcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Removal of gemcitabine‐induced senescent cancer cells by targeting glutaminase1 improves the therapeutic effect in pancreatic ductal adenocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic value of functional SMAD4 localization in extrahepatic bile duct cancer2022

Author(s)

Journal Title

Data Source

[Journal Article] Preoperative FDG-Positive Lymph Nodes Predict the Postoperative Prognosis in Resectable Biliary Tract Cancers2022

Author(s)

Journal Title

Data Source

[Journal Article] ACAT-1-Regulated Cholesteryl Ester Accumulation Modulates Gemcitabine Resistance in Biliary Tract Cancer2022

Author(s)

Journal Title

Data Source

[Journal Article] Endogenous CXCL9 affects prognosis by regulating tumor-infiltrating NK cells in intrahepatic cholangiocarcinoma2020

Author(s)

Iwagami Yoshifumi 岩上佳史

IWAGAMI Yoshifumi 岩上佳史