Kobayashi Yusuke 小林雄祐

… Alternative Names

小林雄祐コバヤシユウスケ

KOBAYASHI Yusuke 小林雄祐

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Researcher Number	60612629
Other IDs	https://orcid.org/0000-0001-7996-3720
Affiliation (Current)	2026: 横浜市立大学, 附属病院, 講師
Affiliation (based on the past Project Information) *help	2024: 横浜市立大学, 附属病院, 講師 2022: 横浜市立大学, 附属病院, 講師 2019 – 2021: 横浜市立大学, 附属病院, 助教 2015: 横浜市立大学, 医学研究科, 客員研究員 2013 – 2015: 横浜市立大学, 医学(系)研究科(研究院), 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 56010:Neurosurgery-related / Kidney internal medicine
Keywords	Principal Investigator SNP / 高血圧 / 一塩基多型 / 生活習慣病 / テーラーメイド医療 / テーラーメード医療 / 治療抵抗性高血圧 / テーラーメード治療 / 進化型機械学習 / ATP2B1 / 動脈硬化 … More Except Principal Investigator … More 低侵襲治療 / 分子概念 / translational research / 分子病態 / 慢性硬膜下血腫 / 本態性高血圧 / LPIN1遺伝子 / ATP2B1遺伝子 Less

慢性硬膜下血腫の潜在性病態：疾患横断的な分子概念の証明と革新的低侵襲治療開発
- Principal Investigator
  
  高瀬創
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yokohama City University
Elucidation of the pathophysiology of the direct association between the hypertension susceptibility gene ATP2B1 and atherosclerosis, and development of therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yusuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yokohama City University
Analysis of new candidate genes for essential hypertension: ATP2B1 gene and LPIN1 gene
- Principal Investigator
  
  UMEMURA Satoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University

All 2024 2023 2019 2015 2014 Other

All Journal Article Presentation

[Journal Article] Using a Quality Management System and Risk-based Approach in Observational Studies to Obtain Robust Real-World Evidence2024
- Author(s)
  Tanoshima Reo、Inagaki Naoko、Nitta Manabu、Sue Soichiro、Shimizu Sayuri、Haze Tatsuya、Senuki Kotaro、Sano Chihiro、Takase Hajime、Kaneko Makoto、Nozaki Akito、Okada Kozo、Ohyama Kohei、Kawaguchi Atsushi、Kobayashi Yusuke、Oi Hideki、Maeda Shin、Yano Yuichiro、Kumagai Yuji、Miyagi Etsuko
- Journal Title
  
  Therapeutic Innovation & Regulatory Science
  
  Volume: 58 Issue: 6 Pages: 1006-1013
- DOI
  10.1007/s43441-024-00695-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08549
[Journal Article] Renin-angiotensin-aldosterone system inhibitors as a risk factor for chronic subdural hematoma recurrence: A matter of debate2023
- Author(s)
  Shimohigoshi Wataru、Takase Hajime、Haze Tatsuya、Kobayashi Yusuke、Manaka Hiroshi、Kawasaki Takashi、Sakata Katsumi、Yamamoto Tetsuya
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 32 Issue: 10 Pages: 107291-107291
- DOI
  10.1016/j.jstrokecerebrovasdis.2023.107291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09167, KAKENHI-PROJECT-23K08549
[Journal Article] Impaired no production and increased blood pressure in systemic heterozygous atp2b1 null mice2014
- Author(s)
  Fujiwara A, Hirawa N, Fujita M, Kobayashi Y, Okuyama Y, Yatsu K, Katsumata M, Yamamoto Y, Ichihara N, Saka S, Toya Y, Umemura S.
- Journal Title
  
  Jourenal of Hypertension
  
  Volume: Published Ahead-of-Print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293196
[Journal Article] Impaired NO Production and Increased Blood Pressure in Systemic Heterozygous ATP2B1 Null Mice.2014
- Author(s)
  Fujiwara A, Hirawa N, Fujita M, Kobayashi Y, Okuyama Y, Yatsu K, Katsumata M, Yamamoto y, Ichihara N, Saka S, Toya Y, Yasuda G, Tabara Y, Miki T, Ueshima H, Ishikawa Y, and Umemura S
- Journal Title
  
  J Hypertension.
  
  Volume: 32 Issue: 7 Pages: 1415-1423
- DOI
  10.1097/hjh.0000000000000206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390084, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293196, KAKENHI-PROJECT-25461249, KAKENHI-PROJECT-25670131
[Presentation] ATP2B1遺伝子の一塩基多型は治療抵抗性高血圧と関連する2019
- Author(s)
  小林雄祐
- Organizer
  第8回臨床高血圧フォーラム
- Data Source
  KAKENHI-PROJECT-19K17610
[Presentation] 全身ヘテロATP2B1欠損マウスにおける高血圧と低Ca血症の関連について2015
- Author(s)
  江原洋介、藤原亮、平和伸仁、角田剛一朗、奥山由紀、藤田恵美、勝又真理、小林雄祐、坂早苗、谷津圭介、戸谷義幸、安田元、梅村敏
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] 遺伝子解析からモデル動物での機能解析への戦略：ATP2B1遺伝子欠損マウス
- Author(s)
  谷津　圭介、平和　伸仁、奥山　由紀、江原　洋介、藤田　恵美、藤原　亮、小林　雄祐、坂　早苗、戸谷　義幸、梅村　敏
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-10-17 – 2014-10-19
- Invited
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] ゲノムワイド解析による高血圧関連遺伝子ATP2B1の発見と遺伝子改変マウスを用いた機能解析
- Author(s)
  平和伸仁、小林雄祐、藤原亮、藤田恵美、奥山由紀、勝又真理、坂早苗、山本有一郎、谷津圭介、戸谷義幸、梅村敏
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] Distal tubules-specific knockout of ATP2B1 is associated with severe polyuria hypertension.
- Author(s)
  Fujita M, Hirawa N, Okuyama Y, Fujiwara A, Kobayashi Y, Saka S, Yatsu K, Nagahama K, Umemura S
- Organizer
  The 14th Asian Pacific Congress of Nephrology
- Place of Presentation
  品川プリンスホテル（東京都港区）
- Year and Date
  2014-05-14 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] LPIN1欠損マウスを用いたLPIN1遺伝子の血圧制御機能の解析
- Author(s)
  奥山　由紀、谷津　圭介、江原　洋介、勝又　真理、藤田　恵美、藤原　亮、小林　雄祐、坂　早苗、平和　伸仁、戸谷　義幸、梅村　敏
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] ATP2B1遺伝子の全身ヘテロノックアウトマウスにおける血圧上昇とNO産生の低下
- Author(s)
  藤原亮、平和伸仁、奥山由紀、藤田恵美、小林雄祐、谷津圭介、戸谷義幸、梅村敏
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Data Source
  KAKENHI-PROJECT-25293196
[Presentation] ATP2B1遺伝子の全身ヘテロノックアウトマウスにおける臓器障害とカルシウム代謝
- Author(s)
  藤原　亮、平和　伸仁、江原　洋介、奥山　由紀、藤田　恵美、勝又　真理、小林　雄祐、坂　早苗、谷津　圭介、戸谷　義幸、梅村　敏
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25293196

1. UMEMURA Satoshi (00128589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. MIZUKI Nobuhisa (90336579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HIRAWA Nobuhito (20315766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. OKA Akira (80384866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YATSU Keisuke (10457856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 高瀬創 (00549975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 石川義弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 藤田孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 下吹越航

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Yusuke 小林 雄祐

小林 雄祐 コバヤシ ユウスケ

KOBAYASHI Yusuke 小林 雄祐

Research Projects

Research Products

Co-Researchers

慢性硬膜下血腫の潜在性病態：疾患横断的な分子概念の証明と革新的低侵襲治療開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathophysiology of the direct association between the hypertension susceptibility gene ATP2B1 and atherosclerosis, and development of therapeutic strategiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of new candidate genes for essential hypertension: ATP2B1 gene and LPIN1 gene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Using a Quality Management System and Risk-based Approach in Observational Studies to Obtain Robust Real-World Evidence2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Renin-angiotensin-aldosterone system inhibitors as a risk factor for chronic subdural hematoma recurrence: A matter of debate2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired no production and increased blood pressure in systemic heterozygous atp2b1 null mice2014

Author(s)

Journal Title

Data Source

[Journal Article] Impaired NO Production and Increased Blood Pressure in Systemic Heterozygous ATP2B1 Null Mice.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] ATP2B1遺伝子の一塩基多型は治療抵抗性高血圧と関連する2019

Author(s)

Organizer

Data Source

[Presentation] 全身ヘテロATP2B1欠損マウスにおける高血圧と低Ca血症の関連について2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 遺伝子解析からモデル動物での機能解析への戦略：ATP2B1遺伝子欠損マウス

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゲノムワイド解析による高血圧関連遺伝子ATP2B1の発見と遺伝子改変マウスを用いた機能解析

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Distal tubules-specific knockout of ATP2B1 is associated with severe polyuria hypertension.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] LPIN1欠損マウスを用いたLPIN1遺伝子の血圧制御機能の解析

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ATP2B1遺伝子の全身ヘテロノックアウトマウスにおける血圧上昇とNO産生の低下

Author(s)

Organizer

Place of Presentation

Kobayashi Yusuke 小林雄祐

小林雄祐コバヤシユウスケ

KOBAYASHI Yusuke 小林雄祐