Nagae Masamichi 長江雅倫

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NAGAE Masamichi 長江雅倫

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Researcher Number	60619873
Other IDs	https://orcid.org/0000-0002-5470-3807
Affiliation (Current)	2024: 大阪大学, 微生物病研究所, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 大阪大学, 微生物病研究所, 助教 2016 – 2018: 東京大学, 大学院薬学系研究科(薬学部), 特任研究員 2016: 理化学研究所, 糖鎖構造生物学研究チーム, 研究員 2015: 国立研究開発法人理化学研究所, 糖鎖構造生物学研究チーム, 研究員 2013 – 2014: 独立行政法人理化学研究所, 糖鎖構造生物学研究チーム, 研究員 2012: 独立行政法人理化学研究所, 糖鎖構造生物学研究チーム, 基幹研究所研究員
Review Section/Research Field	Principal Investigator Structural biochemistry / Biological Sciences / Basic Section 43040:Biophysics-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related / Basic Section 48040:Medical biochemistry-related / Transformative Research Areas, Section (III) / Physical pharmacy
Keywords	Principal Investigator 糖鎖生物学 / 構造生物学 / X線結晶構造解析 / Ｘ線結晶構造解析 / 蛋白質 / 結晶構造解析 / 構造生物化学 / 生化学 / 髄液 / 糖鎖構造解析 … More / GPIアンカー型蛋白質 / 細胞内輸送 / 糖鎖 / 生物物理 / 糖鎖解析 … More Except Principal Investigator N型糖鎖 / Dectin-1 / 糖鎖 / 糖鎖結合分子 / シアル酸結合レクチン / NK細胞 / シグレック / 自然免疫 / 免疫 / Siglec / 分子認識 / シアル酸 / 糖転移酵素 / C型レクチン受容体 / 自己分子 / 免疫センサー / DCIR2 / CLEC-2 / GnT-III / バイセクトGlcNAc / PIM / ZG16p / DCIR / PHA-E / Calsepa / 大量発現 / 気相電気泳動法 / βグルカン / 立体構造 / 分子動力学 / Ｘ線結晶構造解析 / 相互作用 / 分枝構造 / NMR / ダイナミクス / レクチン Less

Mechanisms of protein-selective glycosylation regulated by unique domains of N-glycan branching enzymes
- Principal Investigator
  
  木塚康彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gifu University
Identification of self-derived molecules recognized by immune sensors
- Principal Investigator
  
  山崎晶
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
免疫細胞レクチンシグレックの新規リガンド結合部位の証明と新しい免疫制御機構の解明
- Principal Investigator
  
  佐藤ちひろ
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nagoya University
Structural studies on the variety and universality of GlcNAc transferasesPrincipal Investigator
- Principal Investigator
  
  Nagae Masamichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Osaka University
Structural studies on meta-stable conformations of bisected glycanPrincipal Investigator
- Principal Investigator
  
  Nagae Masamichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
  The University of Tokyo
Structural studies on the pathological mechanism of dystroglycanopathyPrincipal Investigator
- Principal Investigator
  
  Nagae Masamichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
  Institute of Physical and Chemical Research
髄液内におけるN-GlcNAc型糖鎖生成機構の解明Principal Investigator
- Principal Investigator
  
  長江雅倫
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
脂質修飾蛋白質の輸送に関わるp24蛋白質複合体の構造基盤の解明Principal Investigator
- Principal Investigator
  
  長江雅倫
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Structural analysis of asymmetrically branched glycans
- Principal Investigator
  
  Yamaguchi Yoshiki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Institute of Physical and Chemical Research
ＰＳＴによる神経細胞因子ＮＣＡＭのポリシアル化機構の解明Principal Investigator
- Principal Investigator
  
  長江雅倫
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Structural basis for C-type lectin receptor in innate immunityPrincipal Investigator
- Principal Investigator
  
  NAGAE Masamichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b2022
- Author(s)
  Shibata Kensuke、Motozono Chihiro、Nagae Masamichi、Shimizu Takashi、Ishikawa Eri、Motooka Daisuke、Okuzaki Daisuke、Izumi Yoshihiro、Takahashi Masatomo、Fujimori Nao、Wing James B.、Hayano Takahide、Asai Yoshiyuki、Bamba Takeshi、Ogawa Yoshihiro、Furutani-Seiki Makoto、Shirai Mutsunori、Yamasaki Sho
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6948-6948
- DOI
  10.1038/s41467-022-34802-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07539, KAKENHI-PROJECT-22K18924, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-23K23151, KAKENHI-PROJECT-23K24139
[Journal Article] Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)2022
- Author(s)
  Nagae Masamichi、Hirata Tetsuya、Tateno Hiroaki、Mishra Sushil K.、Manabe Noriyoshi、Osada Naoko、Tokoro Yuko、Yamaguchi Yoshiki、Doerksen Robert J.、Shimizu Toshiyuki、Kizuka Yasuhiko
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 695-695
- DOI
  10.1038/s42003-022-03661-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06562, KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors2022
- Author(s)
  Vibhute Amol M.、Tanaka Hide-nori、Mishra Sushil K.、Osuka Reina F.、Nagae Masamichi、Yonekawa Chizuko、Korekane Hiroaki、Doerksen Robert J.、Ando Hiromune、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1866 Issue: 6 Pages: 130118-130118
- DOI
  10.1016/j.bbagen.2022.130118
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-19F01098, KAKENHI-PROJECT-20K06575
[Journal Article] Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-22022
- Author(s)
  Haji Shojiro、Ito Taiki、Guenther Carla、Nakano Miyako、Shimizu Takashi、Mori Daiki、Chiba Yasunori、Tanaka Masato、Mishra Sushil K、Willment Janet A、Brown Gordon D、Nagae Masamichi、Yamasaki Sho
- Journal Title
  
  eLife
  
  Volume: 11
- DOI
  10.7554/elife.83037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20771, KAKENHI-PLANNED-22H05183, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K06575
[Journal Article] Examination of differential glycoprotein preferences of N-acetylglucosaminyltransferase-IV isozymes a and b2022
- Author(s)
  Osada Naoko、Nagae Masamichi、Nakano Miyako、Hirata Tetsuya、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 9 Pages: 102400-102400
- DOI
  10.1016/j.jbc.2022.102400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] Self-referential immune recognition through C-type lectin receptors2022
- Author(s)
  Guenther Carla、Nagae Masamichi、Yamasaki Sho
- Journal Title
  
  Adv. Immunol.
  
  Volume: 156 Pages: 1-23
- DOI
  10.1016/bs.ai.2022.09.001
- ISBN
  9780323989473
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22H05183, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K06575
[Journal Article] N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates.2022
- Author(s)
  Osuka RF, Hirata T, Nagae M, Nakano M, Shibata H, Okamoto R, Kizuka Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 298 Issue: 3 Pages: 101666-101666
- DOI
  10.1016/j.jbc.2022.101666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity2022
- Author(s)
  Tomida Seita、Nagae Masamichi、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 12 Pages: 102676-102676
- DOI
  10.1016/j.jbc.2022.102676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-22KJ1502, KAKENHI-PROJECT-20K06575
[Journal Article] Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients2021
- Author(s)
  Lu X, Hosono Y, Nagae M, Ishizuka S, Ishikawa E, Motooka D, Ozaki Y, Sax N, Maeda Y, Kato Y, Morita T, Shinnakasu R, Inoue T, Onodera T, Matsumura T, Shinkai M, Sato T, Nakamura S, Mori S, Kanda T, Nakayama EE, Shioda T, Kurosaki T, Takeda K, Kumanogoh A, Arase H, Nakagami H, Yamashita K, Takahashi Y, Yamasaki S.
- Journal Title
  
  J Exp Med.
  
  Volume: 218 Issue: 12
- DOI
  10.1084/jem.20211327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H00922, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-21H02740, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-18H05279
[Journal Article] True significance of N-acetylglucosaminyltransferases GnT-III, V and α1,6 fucosyltransferase in epithelial-mesenchymal transition and cancer2020
- Author(s)
  Taniguchi Naoyuki、Ohkawa Yuki、Maeda Kento、Harada Yoichiro、Nagae Masamichi、Kizuka Yasuhiko、Ihara Hideyuki、Ikeda Yoshitaka
- Journal Title
  
  Molecular Aspects of Medicine
  
  Volume: in press Pages: 100905-100905
- DOI
  10.1016/j.mam.2020.100905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-20K07629
[Journal Article] Structural studies of reelin N-terminal region provides insights into a unique structural arrangement and functional multimerization2020
- Author(s)
  Nagae Masamichi、Suzuki Kei、Yasui Norihisa、Nogi Terukazu、Kohno Takao、Hattori Mitsuharu、Takagi Junichi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: mvaa144 Issue: 5 Pages: 1-41
- DOI
  10.1093/jb/mvaa144
- NAID
  40022623693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-20K07051, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-19H02841, KAKENHI-PROJECT-19H03170, KAKENHI-PROJECT-19K22504, KAKENHI-PROJECT-20H03384, KAKENHI-PROJECT-21K19342, KAKENHI-PROJECT-20K20581
[Journal Article] Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs2020
- Author(s)
  Ma Chenyu、Takeuchi Hideyuki、Hao Huilin、Yonekawa Chizuko、Nakajima Kazuki、Nagae Masamichi、Okajima Tetsuya、Haltiwanger Robert S.、Kizuka Yasuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 17 Pages: 6007-6007
- DOI
  10.3390/ijms21176007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-20H03207
[Journal Article] The SH3 domain in the fucosyltransferase FUT8 controls FUT8 activity and localization and is essential for core fucosylation2020
- Author(s)
  Tomida Seita、Takata Misaki、Hirata Tetsuya、Nagae Masamichi、Nakano Miyako、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 23 Pages: 7992-8004
- DOI
  10.1074/jbc.ra120.013079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-18K06115, KAKENHI-PROJECT-20H03207
[Journal Article] 3D Structure and Function of Glycosyltransferases Involved in N-glycan Maturation2020
- Author(s)
  Nagae Masamichi、Yamaguchi Yoshiki、Taniguchi Naoyuki、Kizuka Yasuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 2 Pages: 437-437
- DOI
  10.3390/ijms21020437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19H03362
[Journal Article] Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR2020
- Author(s)
  Omahdi Zakaria、Horikawa Yuto、Nagae Masamichi、Toyonaga Kenji、Imamura Akihiro、Takato Koichi、Teramoto Takamasa、Ishida Hideharu、Kakuta Yoshimitsu、Yamasaki Sho
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 17 Pages: 5807-5817
- DOI
  10.1074/jbc.ra120.012491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04087, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-18K15195, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19H00922
[Journal Article] Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V2020
- Author(s)
  Hirata Tetsuya、Nagae Masamichi、Osuka Reina F.、Mishra Sushil K.、Yamada Mayumi、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 12 Pages: 129726-129726
- DOI
  10.1016/j.bbagen.2020.129726
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-20H03207
[Journal Article] Structural Aspects of Carbohydrate Recognition Mechanisms of C-Type Lectins2019
- Author(s)
  Nagae Masamichi、Yamaguchi Yoshiki
- Journal Title
  
  Current Topics in Microbiology and Immunology
  
  Volume: 1 Pages: 1-30
- DOI
  10.1007/82_2019_181
- ISBN
  9783030622367, 9783030622374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-19H03362
[Journal Article] Biophysical Analyses for Probing Glycan-Protein Interactions2018
- Author(s)
  Nagae Masamichi、Yamaguchi Yoshiki
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1104 Pages: 119-147
- DOI
  10.1007/978-981-13-2158-0_7
- ISBN
  9789811321573, 9789811321580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-16H04758
[Journal Article] Analysis of protein landscapes around N-glycosylation sites from the PDB repository for understanding the structural basis of N-glycoprotein processing and maturation2018
- Author(s)
  Suga Akitsugu、Nagae Masamichi、Yamaguchi Yoshiki
- Journal Title
  
  Glycobiology
  
  Volume: 28 Issue: 10 Pages: 774-785
- DOI
  10.1093/glycob/cwy059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-16H04758
[Journal Article] Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V2018
- Author(s)
  Nagae Masamichi、Kizuka Yasuhiko、Mihara Emiko、Kitago Yu、Hanashima Shinya、Ito Yukishige、Takagi Junichi、Taniguchi Naoyuki、Yamaguchi Yoshiki
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3380-3380
- DOI
  10.1038/s41467-018-05931-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] Crystallographic analysis of murine p24γ2 Golgi dynamics domain2017
- Author(s)
  Nagae M, Liebschner D, Yamada Y, Morita-Matsumoto K, Matsugaki N, Senda T, Fujita M, Kinoshita T, Yamaguchi Y
- Journal Title
  
  Proteins
  
  Volume: 85 Issue: 4 Pages: 764-70
- DOI
  10.1002/prot.25242
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-16H04758
[Journal Article] Distinct roles for each N-glycan branch interacting with mannose-binding type Jacalin-related lectins Orysata and Calsepa.2017
- Author(s)
  Nagae M, Mishra SK, Hanashima S, Tateno H, Yamaguchi Y
- Journal Title
  
  Glycobiology
  
  Volume: 27(12) Issue: 12 Pages: 1120-1133
- DOI
  10.1093/glycob/cwx081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-16H05071, KAKENHI-PROJECT-15K01801, KAKENHI-PROJECT-16H04758
[Journal Article] 3D structural analysis of protein O-mannosyl kinase, POMK, a causative gene product of dystroglycanopathy2017
- Author(s)
  M.Nagae, S.K.Mishra, M.Neyazaki, R.Oi, A.Ikeda, N.Matsugaki, S.Akashi, H.Manya, M.Mizuno, H.Yagi, K.Kato, T.Senda, T.Endo, T.Nogi, and Y.Yamaguchi
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 4 Pages: 348-359
- DOI
  10.1111/gtc.12480
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-26291016, KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-15K07935, KAKENHI-PROJECT-26505009, KAKENHI-PROJECT-16H04758
[Journal Article] Enhancement of solubility and yield of a β-glucan receptor Dectin-1 C-type lectin-like domain in Escherichia coli with a solubility-enhancement tag. Protein2016
- Author(s)
  Dulal HP, Nagae M, Ikeda A, Morita-Matsumoto K, Adachi Y, Ohno N, Yamaguchi Y.
- Journal Title
  
  Expr Purif.
  
  Volume: 123 Pages: 97-104
- DOI
  10.1016/j.pep.2016.04.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-16H04758
[Journal Article] Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins2016
- Author(s)
  Nagae M, Kanagawa M, Morita-Matsumoto K, Hanashima S, Kizuka Y, Taniguchi N, Yamaguchi Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 (22973) Issue: 1 Pages: 1-11
- DOI
  10.1038/srep22973
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PUBLICLY-26110724, KAKENHI-PROJECT-15H04700, KAKENHI-PLANNED-26117008
[Journal Article] 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport.2016
- Author(s)
  Nagae M, Hirata T, Morita-Matsumoto K, Theiler R, Fujita M, Kinoshita T, Yamaguchi Y.
- Journal Title
  
  J Mol Biol.
  
  Volume: 428 Issue: 20 Pages: 4087-99
- DOI
  10.1016/j.jmb.2016.08.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-16H04758
[Journal Article] Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain reveals the binding mode with N-glycan2016
- Author(s)
  Nagae M, Ikeda A, Hanashima S, Kojima T, Matsumoto N, Yamamoto K, Yamaguchi Y.
- Journal Title
  
  FEBS Lett.
  
  Volume: Mar 26 Issue: 8 Pages: 1-9
- DOI
  10.1002/1873-3468.12162
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-16H04758
[Journal Article] Sugar recognition and protein-protein interaction of mammalian lectins conferring diverse functions2015
- Author(s)
  Nagae M, Yamaguchi Y.
- Journal Title
  
  Curr Opin Struct Biol.
  
  Volume: 34 Pages: 108-15
- DOI
  10.1016/j.sbi.2015.08.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460054, KAKENHI-PROJECT-15K18496, KAKENHI-PUBLICLY-26110724, KAKENHI-PLANNED-26117008
[Journal Article] A platform of C-type lectin-like receptor CLEC-2 for binding O-glycosylated podoplanin and nonglycosylated rhodocytin2015
- Author(s)
  Nagae M, Morita-Matsumoto K, Kato M, Kaneko MK, Kato Y, Yamaguchi Y.
- Journal Title
  
  Structure
  
  Volume: 22 Issue: 12 Pages: 1711-1722
- DOI
  10.1016/j.str.2014.09.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25121738, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724, KAKENHI-PROJECT-26440019
[Journal Article] Structural basis for amyloidogenic peptide recognition by sorLA.2015
- Author(s)
  Kitago Y, Nagae M, Nakata Z, Yagi-Utsumi M, Takagi-Niidome S, Mihara E, Nogi T, Kato K, Takagi J.
- Journal Title
  
  Nat Struct Mol Biol.
  
  Volume: 22 Issue: 3 Pages: 199-206
- DOI
  10.1038/nsmb.2954
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PUBLICLY-25121738, KAKENHI-PUBLICLY-26110724
[Journal Article] In situ visualization of a glycoform of transferrin: Localization of α2,6-sialylated transferrin in the liver2015
- Author(s)
  Yuka Matsumoto, Toshie Saito, Kyoka Hoshi, Hiromi Ito, Yoshinobu Kariya, Masamichi Nagae, Yoshiki Yamaguchi, Yoshiaki Hagiwara, Noriaki Kinoshita, Ikuo Wada, Kiyoshi Saito, Takashi Honda and Yasuhiro Hashimoto
- Journal Title
  
  J. Biochem.
  
  Volume: 157(4) Issue: 4 Pages: 211-216
- DOI
  10.1093/jb/mvu071
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-24110511, KAKENHI-PUBLICLY-25121738, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724, KAKENHI-PROJECT-26460394, KAKENHI-PROJECT-15K18496, KAKENHI-PROJECT-25860243
[Journal Article] Structural change of N-glycan exposes hydrophobic surface of human transferrin2014
- Author(s)
  Masamichi Nagae, Kana Morita-Matsumoto, Seisuke Arai, Ikuo Wada, Yuka Matsumoto, Kiyoshi Saito, Yasuhiro Hashimoto and Yoshiki Yamaguchi
- Journal Title
  
  Glycobiology
  
  Volume: 24(8) Issue: 8 Pages: 693-702
- DOI
  10.1093/glycob/cwu033
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110511, KAKENHI-PUBLICLY-25121738, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724, KAKENHI-PROJECT-26460394
[Journal Article] The α-helical region in p24γ2 subunit of p24 protein cargo receptor is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins.2014
- Author(s)
  Theiler R, Fujita M, Nagae M, Yamaguchi Y, Maeda Y, Kinoshita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 289 Issue: 24 Pages: 16835-16843
- DOI
  10.1074/jbc.m114.568311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25121738, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110724
[Journal Article] Three-dimensional structural aspects of protein-polysaccharide interactions.2014
- Author(s)
  Nagae M, Yamaguchi Y.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 15(3) Issue: 3 Pages: 3768-83
- DOI
  10.3390/ijms15033768
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110520, KAKENHI-PROJECT-25460054
[Journal Article] Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold2014
- Author(s)
  M. Nagae, K. Soga, K. Morita-Matsumoto,　S. Hanashima, A. Ikeda, K. Yamamoto, and Y. Yamaguchi
- Journal Title
  
  Glycobiology
  
  Volume: 24 Issue: 4 Pages: 368-78
- DOI
  10.1093/glycob/cwu004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460054
[Journal Article] The alpha helical region of p24γ2 is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins2014
- Author(s)
  Romina Theiler, Morihisa Fujita, Masamichi Nagae, Yoshiki Yamaguchi, Yusuke Maeda, and Taroh Kinoshita
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: in press
- Data Source
  KAKENHI-PUBLICLY-25121738
[Journal Article] Crystal structures of carbohydrate recognition domain of blood dendritic cell antigen-2 (BDCA2) reveal a common domain-swapped dimer.2014
- Author(s)
  Nagae M, Ikeda A, Kitago Y, Matsumoto N, Yamamoto K, Yamaguchi Y.
- Journal Title
  
  Proteins
  
  Volume: 82 Issue: 7 Pages: 1512-1518
- DOI
  10.1002/prot.24504
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-24770111
[Journal Article] Recognition of Bisecting N-Acetylglucosamine: Structural basis for asymmetric interaction with the mouse lectin dendritic cell inhibitory receptor 22013
- Author(s)
  Masamichi Nagae
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 47 Pages: 33598-33610
- DOI
  10.1074/jbc.m113.513572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770102, KAKENHI-PROJECT-24770111, KAKENHI-PUBLICLY-25121730, KAKENHI-PROJECT-25460054
[Journal Article] Crystal structure of anti-polysialic acid antibody single chain Fv fragment complexed with octasialic acid : insight into the binding preference for polysialic acid.2013
- Author(s)
  Nagae M, Ikeda A, Halle M, Hanashima S, Kitajima K, Sato C, Yamaguchi Y.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288 Issue: 47 Pages: 33784-33796
- DOI
  10.1074/jbc.m113.496224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00256, KAKENHI-PROJECT-23570133, KAKENHI-PUBLICLY-24110506, KAKENHI-PUBLICLY-24110520, KAKENHI-PROJECT-25460054
[Journal Article] Lectin-dependent inhibition of antigen-antibody reaction: application for measuringα2,6-sialylated glycoforms of transferrin2013
- Author(s)
  Kyoka Hoshi, Yoshinobu Kariya, Kiyomitsu Nara, Hiromi Ito, Keiro Shirotani, Yasuhiro Hashimoto, et al
- Journal Title
  
  J. Biochem.
  
  Volume: 154(3) Issue: 3 Pages: 229-232
- DOI
  10.1093/jb/mvt065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590367, KAKENHI-PROJECT-23592106, KAKENHI-PUBLICLY-24110511, KAKENHI-PUBLICLY-24110520, KAKENHI-PROJECT-25860243
[Journal Article] Crystal structure of α5β1 integrin ectodomain : Atomic details of the fibronectin receptor2012
- Author(s)
  Nagae, M., et al.
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 197 Issue: 1 Pages: 131-140
- DOI
  10.1083/jcb.201111077
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121513, KAKENHI-PROJECT-22247010, KAKENHI-PROJECT-22370039, KAKENHI-PROJECT-24770111, KAKENHI-PUBLICLY-23121520, KAKENHI-PUBLICLY-24110520, KAKENHI-ORGANIZER-24111001
[Journal Article] Function and 3D structure of the N-glycans on glycoproteins2012
- Author(s)
  Masamichi Nagae, and Yoshiki Yamaguchi
- Journal Title
  
  International journals of molecular science
  
  Volume: 13 Issue: 7 Pages: 8398-8429
- DOI
  10.3390/ijms13078398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770111, KAKENHI-PUBLICLY-24110520
[Presentation] A transient metabolite in Mycobacterium leprae PGL-I biosynthesis pathway is a potent PAMP2023
- Author(s)
  Shigenari Ishizuka, J. Hessel M. van Dijk, Tomomi Kawakita, Yuji Miyamoto, Yumi Maeda, Masamichi Goto, Manabu Ato, Masamichi Nagae, Jeroen D. C. Codee, Sho Yamasaki
- Organizer
  EID会議/日米合同パネル会議 U.S.-Japan Cooperative Medical Sciences Program
- Data Source
  KAKENHI-PLANNED-22H05183
[Presentation] Structural studies of public TCR against SARS-CoV-2 peptide clarified the broad spectrum of the clonotype2022
- Author(s)
  Masamichi Nagae, Shotaro Mori, Sho Yamasaki
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-22H05183
[Presentation] レクチン受容体による結晶性物質の認識機構に関する構造基盤の解明2022
- Author(s)
  長江雅倫、森正太郎、山﨑晶
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PLANNED-22H05183
[Presentation] Self-antigen for mucosal-associated invariant T (MAIT) cell2022
- Author(s)
  Emi Ito, Ami Takeyama, Shotaro Mori, Kensuke Shibata, Eri Ishikawa, Masamichi Nagae and Sho Yamasaki
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-22H05183
[Presentation] レクチン受容体による結晶性物質の認識機構に関する構造基盤の解明2022
- Author(s)
  長江雅倫、森正太郎、山﨑晶
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-20K06575
[Presentation] Structural basis of antigen recognition by distinct public TCRs recognizing an identical epitope conserved across SARS-CoV-2 variants2022
- Author(s)
  Masamichi Nagae, Shotaro Mori, Taiki Ito, Xiuyuan, Lu, Sho Yamasaki
- Organizer
  第51回日本免疫学会年会
- Data Source
  KAKENHI-PROJECT-20K06575
[Presentation] 癌化に関連する糖転移酵素GnT-Vの結晶構造解析2018
- Author(s)
  長江雅倫、木塚康彦、三原恵美子、北郷悠、花島慎弥、伊藤幸成、高木淳一、谷口直之、山口芳樹
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K07303
[Presentation] がん悪性化を促進する糖転移酵素GnT-VのX線結晶構造解析2018
- Author(s)
  長江雅倫、木塚康彦、三原恵美子、北郷悠、花島慎弥、伊藤幸成、高木淳一、谷口直之、山口芳樹
- Organizer
  日本結晶学会平成30年度年会
- Data Source
  KAKENHI-PROJECT-17K07303
[Presentation] Structural studies of cancer-associated glycosyltransferase, GnT-V2018
- Author(s)
  Nagae Masamichi、Kizuka Yasuhiko、Mihara Emiko、Kitago Yu、Hanashima Shinya、Ito Yukishige、Takagi Junichi、Taniguchi Naoyuki、Yamaguchi Yoshiki
- Organizer
  10th Asian Community of Glycoscience and Glycotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07303
[Presentation] ジストログリカノパチー原因遺伝子産物Protein O-Mannosyl Kinase (POMK)の構造解析2017
- Author(s)
  長江雅倫、Sushil K. Mishra、根谷崎牧子、大井里香、池田明美、松垣直宏、明石知子、萬谷博、弘瀬友理子、水野真盛、矢木宏和、加藤晃一、千田俊哉、遠藤玉夫、禾晃和、山口芳樹
- Organizer
  日本糖質学会
- Data Source
  KAKENHI-PROJECT-17K07303
[Presentation] Atomic level visualization of flipped back conformation of bisected glycan, implication for the conformer selection mechanism by lectins2016
- Author(s)
  Masamichi Nagae
- Organizer
  The 3rd International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台国際会議場　（兵庫県淡路市）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054
[Presentation] Glycan dynamics analysed by combined NMR and X-ray crystallography2016
- Author(s)
  Yamaguchi Y, Nagae M, Hanashima S
- Organizer
  8th ACGG Annual Conference
- Place of Presentation
  Wuxi, China
- Year and Date
  2016-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460054
[Presentation] レクチンを利用したN-結合型糖鎖の準安定構造の解析2016
- Author(s)
  山口芳樹、長江雅倫、花島慎弥
- Organizer
  第17回若手NMR研究会in箱根
- Place of Presentation
  箱根高原ホテル（神奈川県足柄下郡）
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-25460054
[Presentation] The effect of bisecting GlcNAc is indirect on binding to PHA-E lectin: A possible role for conformer selection2014
- Author(s)
  Masamichi Nagae, Keisuke Soga, Kana Morita-Matsumoto, Shinya Hanashima, Akemi Ikeda, Kazuo Yamamoto and Yoshiki Yamaguchi
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium
- Place of Presentation
  Max Planck (Kreuth, Germany)
- Year and Date
  2014-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-25460054
[Presentation] Structural analysis of specific recognition mechanism of anti-polysialic acid antibody single chain Fv fragment2013
- Author(s)
  Masamichi Nagae, Akemi Ikeda, Shinya Hanashima, Ken Kitajima, Chihiro Sato, Yoshiki Yamaguchi
- Organizer
  7th International Conference on Structural Genomics (ICSG2013) Structural Life Science
- Place of Presentation
  Sapporo Japan
- Data Source
  KAKENHI-PUBLICLY-24110520
[Presentation] Crystal structure of anti-polysialic antibody single chain Fv fragment in complex with alpha2-8 linked oligosialic acid2013
- Author(s)
  Masamichi Nagae, Akemi Ikeda, Shinya Hanashima, Ken Kitajima, Chihiro Sato, and Yoshiki Yamaguchi
- Organizer
  22nd International Symposium on Glycoconjugates (GLYCO22)
- Place of Presentation
  Dailen China
- Data Source
  KAKENHI-PUBLICLY-24110520
[Presentation] 血小板凝集因子受容体CLEC-2のリガンド認識機構の結晶学的研究
- Author(s)
  長江雅倫、森田加奈、加藤雅樹、金子美華、加藤幸成、山口芳樹
- Organizer
  日本結晶学会2014年度年会
- Place of Presentation
  東京都文京区
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PUBLICLY-25121738
[Presentation] Atomic details of the glycosylation-dependent and independent ligand interactions of C-type lectin-like receptor-2 (CLEC-2)
- Author(s)
  Masamichi Nagae, Kana Morita-Matsumoto, Masaki Kato, Mika Kaneko, Yukinari Kato and Yoshiki Yamaguchi
- Organizer
  Joint meeting of the Society for Glycobiology (SFG) and the Japanese Society of Carbohydrate Research (JSCR)
- Place of Presentation
  Honolulu, Hawaii, US
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-25121738
[Presentation] 血小板凝集因子受容体CLEC-2のリガンド認識機構の結晶学的研究
- Author(s)
  長江雅倫、森田加奈、加藤雅樹、金子美華、加藤幸成、山口芳樹
- Organizer
  日本結晶学会2014年度年会
- Place of Presentation
  東京都文京区
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PUBLICLY-26110724
[Presentation] Atomic details of the glycosylation-dependent and independent ligand interactions of C-type lectin-like receptor-2 (CLEC-2)
- Author(s)
  Masamichi Nagae, Kana Morita-Matsumoto, Masaki Kato, Mika Kaneko, Yukinari Kato and Yoshiki Yamaguchi
- Organizer
  Joint meeting of the Society for Glycobiology (SFG) and the Japanese Society of Carbohydrate Research (JSCR)
- Place of Presentation
  Honolulu, Hawaii, US
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26110724

1. Yamaguchi Yoshiki (90323451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. HANASHIMA Shinya (50373353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. SUGITA Yuji (80311190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 李秀栄 (50390670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山崎晶 (40312946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 井貫晋輔 (70736272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 木塚康彦 (20564743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 田中秀則 (20725064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤ちひろ (10343211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 呉迪 (10817547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中浩士 (40334544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 羽根正弥 (70853331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHBATA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 橋本康弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 城谷圭朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 苅谷慶喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 伊藤浩美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 奈良清光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 真鍋法義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 中の三弥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 高木淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 加藤晃一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 北郷悠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagae Masamichi 長江 雅倫

NAGAE Masamichi 長江 雅倫

Research Projects

Research Products

Co-Researchers

Mechanisms of protein-selective glycosylation regulated by unique domains of N-glycan branching enzymes

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Identification of self-derived molecules recognized by immune sensors

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免疫細胞レクチンシグレックの新規リガンド結合部位の証明と新しい免疫制御機構の解明

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Structural studies on the variety and universality of GlcNAc transferasesPrincipal Investigator

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Structural studies on meta-stable conformations of bisected glycanPrincipal Investigator

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Structural studies on the pathological mechanism of dystroglycanopathyPrincipal Investigator

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髄液内におけるN-GlcNAc型糖鎖生成機構の解明Principal Investigator

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脂質修飾蛋白質の輸送に関わるp24蛋白質複合体の構造基盤の解明Principal Investigator

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Structural analysis of asymmetrically branched glycans

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ＰＳＴによる神経細胞因子ＮＣＡＭのポリシアル化機構の解明Principal Investigator

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Structural basis for C-type lectin receptor in innate immunityPrincipal Investigator

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[Journal Article] Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b2022

Author(s)

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DOI

Data Source

[Journal Article] Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)2022

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DOI

Nagae Masamichi 長江雅倫

NAGAE Masamichi 長江雅倫