Kawashima Akira 川島晃

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KAWASHIMA Akira 川島晃

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Researcher Number	60624913
Other IDs	https://orcid.org/0000-0002-1900-0567
Affiliation (Current)	2024: 帝京大学, 公私立大学の部局等, 教務職員
Affiliation (based on the past Project Information) *help	2024: 帝京大学, 公私立大学の部局等, 教務職員 2016 – 2021: 帝京大学, 医療技術学部, 研究員 2015: 自治医科大学, 医学部, ポスト・ドクター 2015: 自治医科大学, 医学部, 研究員 2013 – 2014: 自治医科大学, 医学部, ポストドクター 2012: 自治医科大学, 医学部, ポスト・ドクター 2011: 国立感染症研究所, ハンセン病研究センター感染制御部, 協力研究員
Review Section/Research Field	Principal Investigator Endocrinology / Basic Section 53050:Dermatology-related Except Principal Investigator Basic Section 52010:General internal medicine-related / Endocrinology
Keywords	Principal Investigator ユビキチン化 / インフラマソーム / ユビキチン / 免疫 / 炎症 / 抗生物質 / 脂質 / 抗酸菌感染症 / 免疫学 / 細胞死 … More / マクロファージ / ユビキチン修飾 / 自然免疫 / 分子間相互作用 / プロテオミクス / 内分泌代謝疾患 / 翻訳後修飾 / 分解 … More Except Principal Investigator サイログロブリン / 甲状腺 / 細胞内シグナル伝達 / 甲状線 / ケモカイン / サイトカイン / インターフェロン / 2本鎖DNA / 自己免疫 / 自然免疫 / 自己免疫疾患 Less

脂質異常症治療薬によるらい菌の宿主細胞内寄生阻害作用の検討Principal Investigator
- Principal Investigator
  
  川島晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Teikyo University
Identification of signaling pathways regulating follicular function by follicular Tg to elucidate the pathogenesis of thyroid diseases
- Principal Investigator
  
  Suzuki Koichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Teikyo University
The study about inflammasome regulation system by protein degradationPrincipal Investigator
- Principal Investigator
  
  Kawashima Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Teikyo University
Identification of inflammasome binding protein and novel signal pathwayPrincipal Investigator
- Principal Investigator
  
  Kawashima Akira
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Jichi Medical University
The study of inflammasome activation system in endocrine and metabolic disorder models.Principal Investigator
- Principal Investigator
  
  KAWASHIMA Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Jichi Medical University
Innate immune activation and thyroid autoimmunity
- Principal Investigator
  
  SUZUKI Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Institute of Infectious Diseases

All 2022 2021 2020 2019 2018 2017 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Regulation of gene expression by follicular thyroglobulin.2022
- Author(s)
  Kiriya M, Kawashima A, Fujiwara Y, Tanimura Y, Yoshihara A, Nakamura Y, Tanigawa K, Kondo T, Suzuki K.
- Journal Title
  
  J Endocrinol Thyroid Res
  
  Volume: 6(4)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07875
[Journal Article] Thyroglobulin regulates the expression and localization of the novel iodide transporter SLC26A7 in thyrocytes.2022
- Author(s)
  Kiriya M, Kawashima A, Fujiwara Y, Tanimura Y, Yoshihara A, Nakamura Y, Tanigawa K, Kondo T, Suzuki K.
- Journal Title
  
  Endocrine J
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07875
[Journal Article] Regulation of solute carrier family 26 member 7 (Slc26a7) by thyroid stimulating hormone in thyrocytes2021
- Author(s)
  Tanimura Yuta、Kiriya Mitsuo、Kawashima Akira、Mori Hitomi、Luo Yuqian、Kondo Tetsuo、Suzuki Koichi
- Journal Title
  
  Endocr J
  
  Volume: 68 Issue: 6 Pages: 691-699
- DOI
  10.1507/endocrj.EJ20-0502
- NAID
  130008057535
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07875
[Journal Article] 自己免疫性甲状腺疾患　－その分子機構－2018
- Author(s)
  川島晃、吉原彩、鈴木幸一
- Journal Title
  
  最新医学
  
  Volume: 73(5) Pages: 657-661
- Data Source
  KAKENHI-PROJECT-16K09808
[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018
- Author(s)
  Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 4 Pages: 744-756
- DOI
  10.1161/atvbaha.117.310581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer2017
- Author(s)
  En Junichiro、Kitamoto Sho、Kawashima Akira、Yonezawa Suguru、Kishi Yoshito、Ishii Norihisa、Goto Masamichi
- Journal Title
  
  PLOS Neglected Tropical Diseases
  
  Volume: 11 Issue: 8 Pages: e0005834-e0005834
- DOI
  10.1371/journal.pntd.0005834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08466, KAKENHI-PROJECT-16K09808
[Journal Article] ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages2017
- Author(s)
  Kawashima Akira、Karasawa Tadayoshi、Tago Kenji、Kimura Hiroaki、Kamata Ryo、Usui-Kawanishi Fumitake、Watanabe Sachiko、Ohta Satoshi、Funakoshi-Tago Megumi、Yanagisawa Ken、Kasahara Tadashi、Suzuki Koichi、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 10 Pages: 3614-3622
- DOI
  10.4049/jimmunol.1700184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K09808, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17K08286, KAKENHI-PROJECT-17K08641, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] Identification of microRNAs that mediate thyroid cell growth induced by TSH2011
- Author(s)
  Akama T, Sue M, Kawashima A, Wu H, Tanigawa K, Suzuki S, Hayashi M, Yoshihara A, Ishido Y, Ishii N, Suzuki K
- Journal Title
  
  Mol Endocrinol
  
  Volume: 26 Issue: 3 Pages: 823-831
- DOI
  10.1210/me.2011-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591187, KAKENHI-PROJECT-24591375
[Journal Article] Fragments of Genomic DNA Released by Injured Cells Activate Innate Immunity and Suppress Endocrine Function in the Thyroid2011
- Author(s)
  Kawashima A, Tanigawa K, Akama T, Wu H, Sue M, Yoshihara A, Ishido Y, Kobiyama K, Takeshita F, Ishii K, Hirano H, Kimura H, Sakai T, Ishii N, Suzuki K
- Journal Title
  
  Endocrinology
  
  Volume: 152(4) Issue: 4 Pages: 1702-1712
- DOI
  10.1210/en.2010-1132
- Data Source
  KAKENHI-PROJECT-21590785, KAKENHI-PROJECT-21591187
[Journal Article] Role of thyroglobulin on negative feedback autoregulation of thyroid follicular function and growth2011
- Author(s)
  Suzuki K, Kawashima A, Yoshihara A, Akama T, Sue M, Yoshida A and Kimura HJ
- Journal Title
  
  J Endocrinol
  
  Volume: 209 Issue: 2 Pages: 169-174
- DOI
  10.1530/joe-10-0486
- Data Source
  KAKENHI-PROJECT-21591187
[Journal Article] Innate immune activation and thyroid autoimmunity2011
- Author(s)
  Kawashima A, Tanigawa K, Akama T, Yoshihara A, Ishii N, Suzuki K
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 96(12) Issue: 12 Pages: 3661-3671
- DOI
  10.1210/jc.2011-1568
- Data Source
  KAKENHI-PROJECT-21591187
[Journal Article] 自己免疫性甲状腺疾患発症の免疫学的機序の基礎と最近の進歩2011
- Author(s)
  鈴木幸一、川島晃
- Journal Title
  
  Medical Practice
  
  Volume: 26 Pages: 1950-1954
- Data Source
  KAKENHI-PROJECT-21591187
[Journal Article] Thyroglobulin (Tg) activates MAPK pathway to induce thyroid cell growth in the absence of TSH, insulin and serum. 420 : 611-615, 20122011
- Author(s)
  Sue M, Hayashi M, Kawashima A, Akama T, Tanigawa K, Yoshihara A, Hara T, Ishido Y, Ito T, Takahashi S-I, Ishii N, Suzuki K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420 Pages: 611-615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591187
[Journal Article] Expression of a thyroglobulin(Tg)variant in mouse kidney glomerulus2009
- Author(s)
  Wu H, Suzuki S, Sellitti D, Doi SQ, Tanigawa K, Aizawa S, Akama T, Kawashima A, Mishima M, Ishii N, Yoshida A, Hisatome I, Koles NL, Katoh R, Suzuki K.
- Journal Title
  
  Biochem Biophys Res Commun 389
  
  Pages: 269-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591187
[Journal Article] Expression of a thyroglobulin(Tg) variant in mouse kidney glomerulus2009
- Author(s)
  Wu H, Suzuki S, Sellitti D, Doi SQ, Tanigawa K, Aizawa S, Akama T, Kawashima A, Mishima M, Ishii N, Yoshida A, Hisatome I, Koles NL, Katoh R and Suzuki K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 389 Issue: 2 Pages: 269-273
- DOI
  10.1016/j.bbrc.2009.08.129
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 新規ヨード輸送体SLC26A7の発現調節機構の解明2022
- Author(s)
  桐谷光夫、谷村優太、川島晃、中村康宏、谷川和也、藤原葉子、近藤哲夫、鈴木幸一
- Organizer
  第37回甲状腺病態生理研究会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] 濾胞内サイログロブリンは甲状腺濾胞上皮内腔側ヨード輸送体であるSLC26A7の発現を抑制する。2021
- Author(s)
  桐谷光夫、川島晃、中村康宏、谷川和也、藤原葉子、近藤哲夫、鈴木幸一
- Organizer
  第25回日本臨床内分泌病理学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] Follicular thyroglobulin regulates expression and localization of Slc26a7, a novel iodide transporter at the apical membrane.2021
- Author(s)
  Mitsuo Kiriya, Yuta Tanimura, Akira Kawashima, Yasuhiro Nakamura, Kazunari Tanigawa, Tetsuo Kondo, Koichi Suzuki.
- Organizer
  43rd Annual Meeting of the European Thyroid Association.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] サイログロブリン（Tg）による新規ヨード輸送体Slc26a7の発現調節機構の解明2020
- Author(s)
  桐谷光夫、谷村優太、川島晃、森仁美、Yuqian Luo、近藤哲夫、鈴木幸一
- Organizer
  第63回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] TSHは甲状腺濾胞上皮内腔側の新規ヨウ素輸送体Slc26a7の発現量を低下させ細胞膜への局在を誘導する2020
- Author(s)
  谷村優太、桐谷光夫、川島晃、森仁美、Yuqian Luo 、近藤哲夫、鈴木幸一
- Organizer
  第61回日本組織細胞化学会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] 甲状腺における新規ヨード輸送体Slc26a7は濾胞内濃度のサイログロブリン（Tg）によって発現調節される2020
- Author(s)
  桐谷光夫、谷村優太、川島晃、森仁美、谷川和也、近藤哲夫、鈴木幸一
- Organizer
  第4回日本ワンヘルスサイエンス学会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] サイログロブリン（Tg）が持つ抗TSH作用機序の検討2019
- Author(s)
  桐谷光夫、川島晃、山中大介、近藤哲夫、鈴木幸一
- Organizer
  第62回日本甲状腺学会
- Data Source
  KAKENHI-PROJECT-19K07875
[Presentation] 自然免疫活性化甲状腺細胞死誘導機構の解明2018
- Author(s)
  牟禮優菜、川島晃、鈴木幸一
- Organizer
  第13回日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09808
[Presentation] ARIH2によるユビキチン修飾を介したNLRP3インフラマソーム抑制機構2018
- Author(s)
  川島　晃、鈴木幸一、高橋将文
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09808
[Presentation] 甲状腺細胞の自然免疫活性化が誘導する細胞死機構の解明2018
- Author(s)
  川島晃、Yuqian、Chen Fei、木村博昭、石藤雄子、鈴木幸一
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09808
[Presentation] PTUはラット甲状腺FRTL-5細胞においてTSH非存在下でMS遺伝子発現とヨード取り込みを誘導する2012
- Author(s)
  須江麻里子、赤間剛、川島晃、中村はな、原武史、谷川和也、Huhehasi Wu、吉原彩、石藤雄子、石井則久、廣井直樹、芳野原、鈴木幸一
- Organizer
  第28回甲状腺病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Regulation of H_2O_2 generation by thyroglobulin in FRTL-52011
- Author(s)
  A. Yoshihara, A. Kawashima, K. Tanigawa, H. Wu, T. Akama, M. Sue, Y. Ishido, N. Hiroi, G. Yoshino, K. Suzuki
- Organizer
  35^<th> Meeting of The European Thyroid Association
- Place of Presentation
  Krakow, Poland
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Fragments of genomic DNA released by injured cells activate innate immunity and suppress endocrine function in the thyroid2011
- Author(s)
  A. Kawashima, F. Takeshita, K. Ishii, K. Suzuki
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] サイログロブリンによるDUOX2を介した甲状腺ホルモン生成制御2011
- Author(s)
  吉原彩、須江麻里子、赤間剛、Huhehasi Wu、川島晃、谷川和也、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第84回日本内分泌学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] PTUはラットFRTL-5細胞においてNIS遺伝子発現とヨード取り込みを誘導する2011
- Author(s)
  須江麻里子、中村はな、川島晃、赤間剛、Huhehasi Wu、谷川和也、吉原彩、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第84回日本内分泌学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] サイログロブリン(Tg)によるDUOX遺伝子発現調節2011
- Author(s)
  吉原彩、谷川和也、川島晃、Huhehasi Wu、赤間剛、須江麻里子、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第27回甲状腺病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] DUOX2によるH_2O_2産生はサイログロブリン(Tg)によって制御される2011
- Author(s)
  吉原彩、川島晃、赤間剛、須江麻里子、Huhehasi Wu、谷川和也、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第54回日本甲状腺学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] microRNAs regulate thyroid cell proliferation induced by TSH and thyroglobulin2011
- Author(s)
  T. Akama, A. Kawashima, H. Wu, K. Tanigawa, M. Sue, A. Yoshihara, Y. Ishido, K. Suzuki
- Organizer
  35^<th> Meeting of The European Thyroid Association
- Place of Presentation
  Krakow, Poland
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 自己免疫性甲状腺疾患発症の免疫学的機序の基礎と最近の進歩2011
- Author(s)
  鈴木幸一、川島晃、赤間剛、吉原彩、須江麻里子
- Organizer
  第27回甲状腺病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] DUOX2によるH2O2産生はサイログロブリン(Tg)によって制御される2011
- Author(s)
  吉原彩、川島晃、赤間剛、須江麻里子、Huhehasi Wu、谷川和也、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第54回日本甲状腺学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] サイログロブリン(Tg)はAkt経路およびMAPK経路を活性化し、 TSHとは異なる経路で細胞増殖を誘導する2010
- Author(s)
  須江麻里子、赤間剛、川島晃、Huhehasi Wu、谷川和也、吉原彩、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第53回日本甲状線学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺細胞傷害によろ露然・獲得免疫反応の誘導機構の解明2010
- Author(s)
  川島晃、谷川和也、Huhehasi Wu、赤間剛、須江麻理子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Expression of a thyroglobulin(Tg) variant in mouse kidney glomerulus2010
- Author(s)
  H. Wu, S. Suzuki, DF. Sellitti, SQ. Doi, K. Tanigawa, S. Aizawa, T. Akama, A. Kawashima, A. Yoshida, I. Hisatome, N. L. Koles, K. Suzuki
- Organizer
  14th International Thyroid Congress
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺細胞傷害による自然・獲得免疫反応の誘導機構の解明2010
- Author(s)
  川島晃、谷川和也、Huhehasi Wu、赤間剛、須江麻理子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺自己免疫発症や機能低ド誘導に関与する新しい因子:病原体、ゲノムDNA断片と免疫プロテアソーム2010
- Author(s)
  鈴木幸一、川島晃、谷川和也、Huhehasi Wu、赤間剛、須江麻里子、吉原彩、石藤雄子、木村博昭
- Organizer
  第14回日本内分泌病理学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] TSIIやtlnrorriobulinによろ甲状腺細胞増殖を制御するmiRNAとその標的遺伝itの同定2010
- Author(s)
  赤間剛、川島晃、Huhehasi Wu、谷川和也、須江麻里子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Thyroglobulin(Tg) activates MAPK pathways to induce thyroid cell growth2010
- Author(s)
  M. Sue, T. Akama, A. Kawashima, H. Wu, K. Tanigawa, Y. Ishido, A. Yoshihara, N. Hiroi, K. Tsuboi, G. Yoshino, K. Suzuki
- Organizer
  14th International Thyroid Congress
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Identification of microRNAs that regulate thyroid physiology2010
- Author(s)
  Takeshi Akama, Akira Kawashima, Huhehasi Wu, Kazunari Tanigawa, Mariko Sue, Yuko Ishido, Koichi Suzuki
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Expression of a thvroglobulin(Tg)variant in mouse kidnev glonierulus2010
- Author(s)
  H.Wu, S.Suzuki, D.F.Sellitti, S.Q.Doi, K.Tanigawa, S.Aizawa, T.Akama, A.Kawashima, A.Yoshida, I.Hisatome, N.L.Koles, K.Suzuki
- Organizer
  14th International Thyroid Congress
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] microRNA(miRNA)によって制御される甲状腺細胞増殖機構の解明2010
- Author(s)
  赤間剛、川島晃、Huhehasi Wu、谷川和也、須江麻里子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第33回日本分子生物学会年会、第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Innate immunity and thyroid autoimmunity2010
- Author(s)
  K.Suzuki, A.Kawashima, K.Tanigawa, H.Wu, T.Akama, M.Sue, A.Yoshihara, Y.Ishido, H.Kimura
- Organizer
  International Molecular Thyroidology Symposium
- Place of Presentation
  長崎(招待講演)
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] サイログロブリン(Tg)はAkt経路およびMAPK経路を活性化し、TSHとは異なる経路で細胞増殖を誘導する2010
- Author(s)
  須江麻里子、赤間剛、川島晃、Huhehasi Wu、谷川和也、吉原彩、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Thvroglobulin(Tg)activates MAPK pathways to induce thyroid cell growth2010
- Author(s)
  M.Sue, T.Akama, A.Kawashima, H.Wu, K.Tanigawa, Y.Ishido, A.Yoshihara, N.Hiroi, K.Tsuboi, G.Yoshino, K.Suzuk.
- Organizer
  14th International Thyroid Congress
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺自己免疫発症や機能低下誘導に関与する新しい因子:病原体、ゲノムDNA断片と免疫プロテアソーム2010
- Author(s)
  鈴木幸一、川島晃、谷川和也、Huhehasi Wu、赤間剛、須江麻里子、吉原彩、石藤雄子、木村博昭
- Organizer
  第14回日本内分泌病理学会、シンポジウム「難治性甲状腺疾患と病理」
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] microRNA(miRNA)によって制御される甲状腺細胞増殖機構の解明2010
- Author(s)
  赤間剛、川島晃、Huhehasi Wu、谷川和也、須江麻里子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第33回日本分子生物学会年会、第83回田本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Innate immunity and thyroid autoimmunity. International Molecular Thyroidology Symposium2010
- Author(s)
  K. Suzuki, A. Kawashima, K. Tanigawa, H. Wu, T. Akama, M. Sue, A. Yoshihara, Y. Ishido and H. Kimura
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Identification of microRNAs that regulate thyroid physiology2010
- Author(s)
  T. Akama, A. Kawashima, H. Wu, K. Tanigawa, M. Sue, Y. Ishido and K. Suzuki
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] TSHやthyroglobulinによる甲状腺細胞増殖を制御するmiRNAとその標的遺伝子の同定2010
- Author(s)
  赤間剛、川島晃、Huhehasi Wu、谷川和也、須江麻里子、吉原彩、石藤雄子、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] DNAマイクロアレイを用いたサイログロブリン(Tg)による甲状腺遺伝子発現変化の検討2010
- Author(s)
  吉原彩、須江麻里子、赤間剛、Huhehasi Wu、川島晃、谷川和也、石藤雄子、廣井直樹、芳野原、鈴木幸一
- Organizer
  第53回日本甲状腺学会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] The effect of anti-thyroid drugs on Sodium-Iodide-Symporter(NIS) expression in rat thyroid FRTL-5 cells2010
- Author(s)
  M. Sue, H. Nakamura, A. Kawashima, Y. Ishido, H. Wu, T. Akama, K. Tanigawa, LD. Kohn, K. Suzuki
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] TSH and thyroglobulin modulate microRNA expression that regulate thyroid cell growth2010
- Author(s)
  T. Akama, A. Kawashima, H. Wu, K. Tanigawa, M. Sue, A. Yoshihara, Y. Ishido, K. Suzuki
- Organizer
  14th International Thyroid Congress
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺細胞傷害によって漏出する二本鎖DNAが誘導する自然免疫機構の解明2009
- Author(s)
  川島晃、谷川和也、Huhehasi Wu、赤間剛、石井則久、武下文彦、鈴木幸一
- Organizer
  第82回日本内分泌学会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 甲状腺細胞傷害による内因性アジュバンド放出が自己抗原提示の誘因となる可能性2009
- Author(s)
  川島晃、谷川和也、Huhehasi Wu、赤間剛、林もゆる、石藤雄子、石井則久、武下文彦、平野久、鈴木幸一
- Organizer
  第25回甲状腺病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-31
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] マウス腎臓におけるサイログロブリン遺伝子断片の発現と意義2009
- Author(s)
  Huhehasi Wu、鈴木さゆり、Donald F. Sellitti、Sonia Q. Doi、赤間剛、相沢清香、川島晃、谷川和也、吉田明雄、加藤良平、鈴木幸一
- Organizer
  第13回日本内分泌病理学会学術総会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] Molecular cloning and characterization of a novel thyroglobulin(Tg)variant in mouse kidney2009
- Author(s)
  Wu H, Suzuki S, Sellitti DF, Doi SQ, Aizawa S, Tanigawa K, Akama T, Kawashima A, Mishima M, Ishii N, Yoshida A, Hisatome I, Koles N, Katoh R, Suzuki K.
- Organizer
  80th Annual Meeting of The American Thyroid Association
- Place of Presentation
  Palm Beach, Florida
- Data Source
  KAKENHI-PROJECT-21591187
[Presentation] 抗甲状腺薬が甲状腺機能遺伝子発現に与える影響の違い2009
- Author(s)
  須江麻里子、中村はな、川島晃、石藤雄子、Huhehasi Wu、赤間剛、谷川和也、Leonard D. Kohn、鈴木幸一
- Organizer
  第52回日本甲状腺学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591187

1. SUZUKI Koichi (20206478)

# of Collaborated Projects: 4 results

# of Collaborated Products: 55 results
2. TANIGAWA Kazunari (10443110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 39 results
3. AKAMA Takeshi (20575253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 41 results
4. 高橋将文 (40296108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 木村博昭 (70593622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 唐澤直義 (60631893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 渡邊幸子 (80770619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 山中大介 (10553266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 三上万理子 (20840276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. EN Junichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. USUI Fumitake

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 坂井貴文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 後藤正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawashima Akira 川島 晃

KAWASHIMA Akira 川島 晃

Research Projects

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Co-Researchers

脂質異常症治療薬によるらい菌の宿主細胞内寄生阻害作用の検討Principal Investigator

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Identification of signaling pathways regulating follicular function by follicular Tg to elucidate the pathogenesis of thyroid diseases

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The study about inflammasome regulation system by protein degradationPrincipal Investigator

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Identification of inflammasome binding protein and novel signal pathwayPrincipal Investigator

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The study of inflammasome activation system in endocrine and metabolic disorder models.Principal Investigator

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Innate immune activation and thyroid autoimmunity

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[Journal Article] Regulation of gene expression by follicular thyroglobulin.2022

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[Journal Article] Thyroglobulin regulates the expression and localization of the novel iodide transporter SLC26A7 in thyrocytes.2022

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[Journal Article] Regulation of solute carrier family 26 member 7 (Slc26a7) by thyroid stimulating hormone in thyrocytes2021

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[Journal Article] 自己免疫性甲状腺疾患 －その分子機構－2018

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[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018

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[Journal Article] Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer2017

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[Journal Article] ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages2017

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[Journal Article] Identification of microRNAs that mediate thyroid cell growth induced by TSH2011

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Kawashima Akira 川島晃

KAWASHIMA Akira 川島晃

[Journal Article] 自己免疫性甲状腺疾患　－その分子機構－2018