Takahata Yoshifumi 高畑佳史

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TAKAHATA Yoshifumi 高畑佳史

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Researcher Number	60635845
Other IDs	https://orcid.org/0000-0002-3322-0515
Affiliation (Current)	2024: 大阪大学, 大学院歯学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院歯学研究科, 准教授 2022 – 2023: 大阪大学, 大学院歯学研究科, 助教 2016 – 2021: 大阪大学, 歯学研究科, 助教 2017: 大阪大学, 大学院歯学研究科, 助教 2014 – 2015: 大阪大学, 歯学研究科(研究院), 助教 2012 – 2013: 金沢大学, 自然システム学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 57010:Oral biological science-related / Functional basic dentistry / Biological pharmacy / Genome biology Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Functional basic dentistry
Keywords	Principal Investigator 転写因子 / 発生 / 軟骨分化 / 骨形成 / シグナル伝達 / 軟骨細胞 / 概日リズム / 時計遺伝子 / 骨格形成 / Runx2 … More / 軟骨形成 / プロテインキナーゼ / CRISPR/Cas9 / リン酸化シグナル / RNA seq / ゲノム編集 / リン酸化 / 薬理学 / 生理活性 / 歯学 / 細胞・組織 / Sox9 / ネガティブフィードバック機構 / 転写制御因子 / サーカディアンリズム / Period … More Except Principal Investigator 転写因子 / 関節リウマチ / 細胞内シグナル / 軟骨 / ゲノム編集 / 骨 / 軟骨代謝 / 関節軟骨 / 創薬 / 変形性関節症 / 軟骨細胞 / セマフォリン / 骨粗鬆症 / 自己免疫疾患 / 骨形成 / 転写プラットフォーム / 内軟骨性骨形成 / Zfhx4 / 骨系統疾患 / 骨代謝 / 炎症 / 炎症性サイトカイン / 骨免疫学 / 再生 / ダイレクトリプログラミング / 関節軟骨生物学 / サイトカイン / Prg4 / Gdf5 / 関節軟骨細胞 / 遺伝子クローニング / 軟骨分化 Less

Development of novel curative strategies for bone and cartilage diseases based on non-classical Sema4D signalling pathways
- Principal Investigator
  
  西村理行
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
炎症性ドライバーIκBζの相反性の理解から挑む自己免疫疾患の発症機序の解明と応用
- Principal Investigator
  
  西村理行
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
転写プラットフォーム因子Zfhxファミリーによる骨格形成の時空間的制御機構の解明
- Principal Investigator
  
  西村理行
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
転写因子Runx2の標的遺伝子の同定と骨格形成における機能解析Principal Investigator
- Principal Investigator
  
  高畑佳史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Osaka University
New Opportunity in Bone Immunology to Establish a Drug Discovery Platform for Molecular Targeted Therapeutics for Bone and Cartilage Destructive Diseases.
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Analysis of signal molecules of protein kinases involved in chondrocyte differentiation and cartilage formationPrincipal Investigator
- Principal Investigator
  
  Takahata Yoshifumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Osaka University
Analysis of novel transcription factors controlling cartilage formationPrincipal Investigator
- Principal Investigator
  
  Yoshifumi Takahata
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Investigation of transcriptional network system of chondrocytes by novel gene-editing cloning technique
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Development of innovative medical technology based on integrated understanding of both protection and destruction of articular cartilage homeostasis.
- Principal Investigator
  
  Nishimura Riko
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Functional analysis of a novel molecular mechanism of circadian clock genes.Principal Investigator
- Principal Investigator
  
  Takahata Yoshifumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Functional analysis of a transcriptional feedback loop related to a mammalian clock gene, PeriodPrincipal Investigator
- Principal Investigator
  
  TAKAHATA Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Genome biology
- Research Institution
  Kanazawa University

All 2023 2022 2021 2020 2019 2018 2017 2013 Other

All Journal Article Presentation Other

[Journal Article] Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx22022
- Author(s)
  Yagi Hiroko、Takahata Yoshifumi、Murakami Tomohiko、Nakaminami Yuri、Hagino Hiromasa、Yamamoto Shiori、Murakami Shinya、Hata Kenji、Nishimura Riko
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 40 Issue: 5 Pages: 723-734
- DOI
  10.1007/s00774-022-01345-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20K20475
[Journal Article] The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival.2022
- Author(s)
  Inubushi T, Nakanishi Y, Abe M, Takahata Y, Nishimura R, Kurosaka H, Irie F, Yamashiro T, Yamaguchi Y.
- Journal Title
  
  PLoS Genetics
  
  Volume: 18(7) Issue: 7 Pages: e1009765-e1009765
- DOI
  10.1371/journal.pgen.1009765
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20K20475
[Journal Article] Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis2022
- Author(s)
  Takahata Yoshifumi, Hagino Hiromasa, Kimura Ayaka, Urushizaki Mitsuki, Yamamoto Shiori, Wakamori Kanta, Murakami Tomohiko, Hata Kenji, Nishimura Riko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 9 Pages: 4672-4672
- DOI
  10.3390/ijms23094672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09827, KAKENHI-PROJECT-21K19596, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20K20475
[Journal Article] Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes2022
- Author(s)
  Murakami Tomohiko、Takahata Yoshifumi、Hata Kenji、Ebina Kosuke、Hirose Katsutoshi、Ruengsinpinya Lerdluck、Nakaminami Yuri、Etani Yuki、Kobayashi Sachi、Maruyama Takashi、Nakano Hiroyasu、Kaneko Takehito、Toyosawa Satoru、Asahara Hiroshi、Nishimura Riko
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 758
- DOI
  10.1126/scisignal.abl5304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K09410, KAKENHI-PROJECT-20K09460, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K16708, KAKENHI-PROJECT-23K24519
[Journal Article] Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx22021
- Author(s)
  Ono Koichiro、Hata Kenji、Nakamura Eriko、Ishihara Shota、Kobayashi Sachi、Nakanishi Masako、Yoshida Michiko、Takahata Yoshifumi、Murakami Tomohiko、Takenoshita Seiichi、Komori Toshihisa、Nishimura Riko、Yoneda Toshiyuki
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-021-01848-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-20K18775, KAKENHI-PROJECT-19K22708, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-20F20407
[Journal Article] Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx22021
- Author(s)
  Takahata Yoshifumi、Hagino Hiromasa、Kimura Ayaka、Urushizaki Mitsuki、Kobayashi Sachi、Wakamori Kanta、Fujiwara Chika、Nakamura Eriko、Yu Kayon、Kiyonari Hiroshi、Bando Kana、Murakami Tomohiko、Komori Toshihisa、Hata Kenji、Nishimura Riko
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1199-1199
- DOI
  10.1038/s42003-021-02717-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-21K09827, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K19596
[Journal Article] Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice2021
- Author(s)
  Nakamura Eriko、Hata Kenji、Takahata Yoshifumi、Kurosaka Hiroshi、Abe Makoto、Abe Takaya、Kihara Miho、Komori Toshihisa、Kobayashi Sachi、Murakami Tomohiko、Inubushi Toshihiro、Yamashiro Takashi、Yamamoto Shiori、Akiyama Haruhiko、Kawaguchi Makoto、Sakata Nobuo、Nishimura Riko
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1258-1258
- DOI
  10.1038/s42003-021-02793-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18H05283, KAKENHI-PROJECT-21H04841, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-20F20407, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-21K19596, KAKENHI-PROJECT-16H06276
[Journal Article] Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases2020
- Author(s)
  Nishimura Riko、Hata Kenji、Takahata Yoshifumi、Murakami Tomohiko、Nakamura Eriko、Ohkawa Maki、Ruengsinpinya Lerdluck
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1340-1340
- DOI
  10.3390/ijms21041340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09518, KAKENHI-PROJECT-19K22708, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-19H03824, KAKENHI-PROJECT-19H03836, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-18K19640
[Journal Article] G protein subunit β1 is an important mediator of the late stage of endochondral ossification.2020
- Author(s)
  Ruengsinpinya L, Murakamia T, Nakamura E, Takahata Y, Hata K, Nakaminamia Y, Okaeb H, Nishimura R.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] Role of interleukin-1 and inflammasomes in oral disease2020
- Author(s)
  Murakami T, Takahata Y, Hata K, Nishimura R
- Journal Title
  
  J Oral Biosci
  
  Volume: 62 Pages: 242-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.2020
- Author(s)
  Takahata Y, Murakami T, Hata K, Nishimura R．
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 14 Pages: 165-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20475
[Journal Article] Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.2020
- Author(s)
  Takahata Y, Murakami T, Hata K, Nishimura R.
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 13 Issue: 2 Pages: 1-6
- DOI
  10.2174/1874467213666200417122933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-20K20475, KAKENHI-PROJECT-19K22708
[Journal Article] Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS52019
- Author(s)
  Takahata Yoshifumi、Nakamura Eriko、Hata Kenji、Wakabayashi Makoto、Murakami Tomohiko、Wakamori Kanta、Yoshikawa Hiroshi、Matsuda Akio、Fukui Naoshi、Nishimura Riko
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 1 Pages: 619-630
- DOI
  10.1096/fj.201800259r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-18K09049
[Journal Article] Cutting Edge: G Protein Subunit b 1 Negatively Regulates NLRP3 Inflammasome Activation2019
- Author(s)
  Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura,Yoshifumi Takahata, Kenji Hata, Hiroaki Okae,Shun’ichiro Taniguchi, Masafumi Takahashi and Riko Nishimura
- Journal Title
  
  The Journal of Immunology
  
  Volume: 202 Issue: 7 Pages: 1942-1947
- DOI
  10.4049/jimmunol.1801388
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19H03824
[Journal Article] Transcriptional network systems in cartilage development and disease2018
- Author(s)
  Nishimura Riko、Hata Kenji、Nakamura Eriko、Murakami Tomohiko、Takahata Yoshifumi
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 149 Issue: 4 Pages: 353-363
- DOI
  10.1007/s00418-017-1628-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15788, KAKENHI-PROJECT-16H06393
[Journal Article] Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a2018
- Author(s)
  Kida Jumpei、Hata Kenji、Nakamura Eriko、Yagi Hiroko、Takahata Yoshifumi、Murakami Tomohiko、Maeda Yoshinobu、Nishimura Riko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10375-10375
- DOI
  10.1038/s41598-018-28711-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270
[Journal Article] Regulation of Cartilage Development and Diseases by Transcription Factors2017
- Author(s)
  Nishimura Riko、Hata Kenji、Takahata Yoshifumi、Murakami Tomohiko、Nakamura Eriko、Yagi Hiroko
- Journal Title
  
  J Bone Metab
  
  Volume: 24 Issue: 3 Pages: 147-147
- DOI
  10.11005/jbm.2017.24.3.147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15779, KAKENHI-PROJECT-16K15788
[Journal Article] Transcriptional network controlling endochondral ossification2017
- Author(s)
  Hata K, Takahata Y, Murakami T, Nishimura R
- Journal Title
  
  J Bone Metab
  
  Volume: 24 Issue: 2 Pages: 75-82
- DOI
  10.11005/jbm.2017.24.2.75
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19749, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-16K15788
[Presentation] Axon guidance molecule Semaphorin 4D induces cartilage destruction by activating non-canonical signaling pathway2023
- Author(s)
  Murakami T, Takahata Y, Hata K, Ebina K, Hirose K, Nakaminami Y, Toyosawa S, Asahara H, Nishimura R
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 骨軟骨形成におけるGタンパク質サブユニットβ1の機能解析2022
- Author(s)
  村上智彦、高畑佳史、波多賢二、中南友里、西村理行
- Organizer
  第40回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 小胞体ストレスはリポ多糖に対する炎症応答を増強する2022
- Author(s)
  中南友里，村上智彦，高畑佳史，波多賢二，西村理行
- Organizer
  第64回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2022
- Author(s)
  Hata K, Kobayash S, Takahata Y, Murakami T, Nishimura R
- Organizer
  Japan Bone Academy 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Runx2の新規標的分子の同定と骨形成における機能的役割2022
- Author(s)
  Takahata Yoshifumi, Murakami Tomohiko, Hata Kenji, Nishimura Riko
- Organizer
  第６５回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09827
[Presentation] Challenging of identification of genes in the onset and progression of pathogenesis of osteoarthritis2022
- Author(s)
  Yamamoto S, Hagino H, Murakami T, Hata K, Nishimura R, Takahata Y
- Organizer
  第３５回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Dmrt2 promotes transition of endochondral ossification by linking Sox9 and Runx22021
- Author(s)
  Hata K, Ono K, Nakamura E, Kobayashi S, Takahata Y, Murakami T, Nishimura R
- Organizer
  48th annual meeting of the European Calcified Tissue Society（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04841
[Presentation] Identification of Chondrocyte-specific Sox9 Enhancers Important for Skeletal Development2021
- Author(s)
  Kobayashi S, Hata K, Takahata Y, Murakami T, Uzawa N, Nishimura R.
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] 軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析2021
- Author(s)
  小林　紗知, 波多　賢二, 高畑　佳史，村上　智彦，西村　理行
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20475
[Presentation] Identification and functional analysis of novel target genes regulated by Runx2.2019
- Author(s)
  Takahata Yoshifumi, Wakamori Kanta, Fujiwara Chica, Nakamura Eriko, Hata Kenji, Murakami Tomohiko, Nishimura Riko
- Organizer
  IFMRS 3rd Herbert Fleisch Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] 転写制御と骨格系疾患の分子機構2018
- Author(s)
  波多　賢二、村上　智彦、高畑　佳史、西村　理行
- Organizer
  第60回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06393
[Presentation] Functional analysis of transcriptional regulation of a mammalian clock gene, Bmal12013
- Author(s)
  Yuki Ohba, Ken Matsumoto, Yoshifumi Takahata, Yoshiaki Fujii-Kuriyama and Hajime Tei1
- Organizer
  第３６回分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24810009
[Presentation] Functional analysis of transcriptional regulation of a mammalian clock gene, Bmal12013
- Author(s)
  Yuki Ohba, Ken Matsumoto, Yoshifumi Takahata, Yoshiaki Fujii-Kuriyama and Hajime Tei
- Organizer
  第36回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-24810009
[Presentation] 哺乳類時計遺伝子Bmal1の新規転写制御機構の解析
- Author(s)
  大場祐希, 松本健, 高畑佳史, 藤井義明, 程肇
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860036
[Presentation] 哺乳類時計遺伝子Rev-erbαの転写制御機構の解析
- Author(s)
  松浦知諒, 高畑佳史, 山田洋一, 程肇
- Organizer
  第３７回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860036
[]

1. Nishimura Riko (60294112)

# of Collaborated Projects: 6 results

# of Collaborated Products: 27 results
2. HATA KENJI (80444496)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
3. MURAKAMI TOMOHIKO (50510723)

# of Collaborated Projects: 6 results

# of Collaborated Products: 29 results
4. 美島健二 (50275343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahata Yoshifumi 高畑 佳史

TAKAHATA Yoshifumi 高畑 佳史

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Development of novel curative strategies for bone and cartilage diseases based on non-classical Sema4D signalling pathways

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炎症性ドライバーIκBζの相反性の理解から挑む自己免疫疾患の発症機序の解明と応用

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転写プラットフォーム因子Zfhxファミリーによる骨格形成の時空間的制御機構の解明

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転写因子Runx2の標的遺伝子の同定と骨格形成における機能解析Principal Investigator

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New Opportunity in Bone Immunology to Establish a Drug Discovery Platform for Molecular Targeted Therapeutics for Bone and Cartilage Destructive Diseases.

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Analysis of signal molecules of protein kinases involved in chondrocyte differentiation and cartilage formationPrincipal Investigator

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Analysis of novel transcription factors controlling cartilage formationPrincipal Investigator

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Investigation of transcriptional network system of chondrocytes by novel gene-editing cloning technique

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Development of innovative medical technology based on integrated understanding of both protection and destruction of articular cartilage homeostasis.

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Functional analysis of a novel molecular mechanism of circadian clock genes.Principal Investigator

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Functional analysis of a transcriptional feedback loop related to a mammalian clock gene, PeriodPrincipal Investigator

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[Journal Article] Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx22022

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[Journal Article] The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival.2022

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Takahata Yoshifumi 高畑佳史

TAKAHATA Yoshifumi 高畑佳史