Yamanaka Yoshiaki 山中芳亮

Researcher Number	60644862
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 産業医科大学, 医学部, 講師 2021 – 2022: 産業医科大学, 医学部, 助教 2019 – 2020: 産業医科大学, 医学部, 学内講師 2018 – 2019: 産業医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator 線維化 / アディポサイトカイン / アディポネクチン / 関節拘縮 / IRS / 糖尿病 / インスリン受容体基質 / 2型糖尿病 / 線維芽細胞 / TGF-β … More / エストラジオール / コラーゲン / 特発性手根管症候群 / 性ステロイドホルモン … More Except Principal Investigator 股関節唇 / リラキシン受容体 / リラキシンファミリーペプチド受容体1 / リラキシン / 変形性股関節症 / 寛骨臼形成不全 / 大腿骨寛骨臼インピンジメント / 股関節 / MUNE / BDNF / 神経再生 / 電気刺激療法 / 肘部管症候群 Less

Elucidation of Joint contracture mechanisms focusing on adipocytokinesPrincipal Investigator
- Principal Investigator
  
  山中芳亮
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The Involvement and the Regulatory Mechanism of Relaxin in Hip Osteoarthritis - Efforts toward Clinical Application
- Principal Investigator
  
  内田宗志
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
肘部管症候群における術中末梢神経電気刺激療法ー神経再生とBDNF遺伝子多型ー
- Principal Investigator
  
  蜂須賀明子
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Evaluation of tissue fibrosis mechanism associated with type 2 diabetes mouse focusing on insulin receptor substratePrincipal Investigator
- Principal Investigator
  
  Yamanaka Yoshiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Elucidation of the mechanism of tissue fibrosis focusing on estradiolPrincipal Investigator
- Principal Investigator
  
  Yamanaka Yoshiaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Molecular and Clinical Elucidation of the Mechanism of Action of Steroids in Idiopathic Carpal Tunnel Syndrome2021
- Author(s)
  Yamanaka Yoshiaki、Tajima Takafumi、Tsujimura Yoshitaka、Kosugi Kenji、Mano Yosuke、Zenke Yukichi、Hachisuka Akiko、Aoki Takatoshi、Sakai Akinori
- Journal Title
  
  Journal of Bone and Joint Surgery
  
  Volume: 103 Issue: 19 Pages: 1777-1787
- DOI
  10.2106/jbjs.20.02096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-21K11304, KAKENHI-PROJECT-20K18047, KAKENHI-PROJECT-18K17701
[Journal Article] Effect of a monocyte chemoattractant protein-1 synthesis inhibitor on fibroblasts from patients with carpal tunnel syndrome2021
- Author(s)
  Yamanaka Yoshiaki、Gingery Anne、Oki Gosuke、Yang Tai-Hua、Zhao Chunfeng、Amadio Peter C.
- Journal Title
  
  Journal of Orthopaedic Science
  
  Volume: 26 Issue: 2 Pages: 295-299
- DOI
  10.1016/j.jos.2020.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18047
[Journal Article] Development of a novel knee contracture mouse model by immobilization using external fixation2021
- Author(s)
  Tokuda Kotaro、Yamanaka Yoshiaki、Kosugi Kenji、Nishimura Haruki、Okada Yasuaki、Tsukamoto Manabu、Tajima Takafumi、Suzuki Hitoshi、Kawasaki Makoto、Uchida Soshi、Nakamura Eiichiro、Wang Ke-Yong、Sakai Akinori
- Journal Title
  
  Connective Tissue Research
  
  Volume: 63 Issue: 2 Pages: 169-182
- DOI
  10.1080/03008207.2021.1892088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-20K18047, KAKENHI-PROJECT-20K09446
[Journal Article] Effect of metformin treatment and its time of administration on joint capsular fibrosis induced by mouse knee immobilization2021
- Author(s)
  Tokuda Kotaro、Yamanaka Yoshiaki、Mano Yosuke、Tsukamoto Manabu、Tajima Takafumi、Suzuki Hitoshi、Kawasaki Makoto、Uchida Soshi、Nakamura Eiichiro、Wang Ke-Yong、Sakai Akinori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 17978-17978
- DOI
  10.1038/s41598-021-97445-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18547, KAKENHI-PROJECT-20K09421, KAKENHI-PROJECT-20K18047
[Journal Article] エストラジオールが閉経後特発性手根管症候群患者の手根管内屈筋腱滑膜に与える効果2019
- Author(s)
  山中芳亮, 目貫邦隆, 田島貴文, 岡田祥明, 小杉健二, 善家雄吉, 酒井昭典
- Journal Title
  
  末梢神経
  
  Volume: 30 Pages: 76-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16677
[Journal Article] Effect of estradiol on fibroblasts from postmenopausal idiopathic carpal tunnel syndrome patients2018
- Author(s)
  Yamanaka Yoshiaki、Menuki Kunitaka、Tajima Takafumi、Okada Yasuaki、Kosugi Kenji、Zenke Yukichi、Sakai Akinori
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 233 Issue: 11 Pages: 8723-8730
- DOI
  10.1002/jcp.26752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] 糖尿病モデルマウスにおける膝関節拘縮機序の検討2023
- Author(s)
  内藤東一郎、山中芳亮、徳田昂太郎、辻村良賢、田島貴文、塚本学、鈴木仁士、川崎展、中村英一郎、酒井昭典
- Organizer
  第55回日本結合組織学会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023
- Author(s)
  内藤東一郎、山中芳亮、徳田昂太郎、辻村良賢、田島貴文、塚本学、鈴木仁士、川崎展、中村英一郎、酒井昭典
- Organizer
  第38回日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023
- Author(s)
  内藤東一郎, 山中芳亮, 佐藤直人, 田島貴文, 塚本学, 鈴木仁士, 川崎展, 中村英一郎, 酒井昭典
- Organizer
  日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-23K08599
[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023
- Author(s)
  内藤東一郎, 山中芳亮, 佐藤直人, 田島貴文, 塚本学, 鈴木仁士, 川崎展, 中村英一郎, 酒井昭典
- Organizer
  日本結合組織学会
- Data Source
  KAKENHI-PROJECT-23K08599
[Presentation] Adiponectin inhibits fibrosis of fibroblasts in the palmar aponeurosis in Dupuytren's contracture2023
- Author(s)
  山中芳亮、内藤東一郎、田島貴文、辻村良賢、目貫邦隆、大茂壽久、戸羽直樹、善家雄吉、酒井昭典
- Organizer
  Orthopaedic Research Society 2023 annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] トリアムシノロンの抗線維化作用に着目した特発性手根管症候群患者における手根管内滑膜線維化機序の解明2022
- Author(s)
  山中芳亮, 田島貴文, 辻村良賢, 真野洋佑, 酒井昭典, 善家雄吉, 蜂須賀明子, 青木隆敏
- Organizer
  第39回産業医科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] CCL2に着目した特発性手根管症候群の発症機序の解明2021
- Author(s)
  山中芳亮, 田島貴文, 辻村良賢, 小杉健二, 真野洋佑, 善家雄吉, 酒井昭典
- Organizer
  第38回産業医科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] 関節拘縮抑制効果を有するメトホルミンの適切な投与時期の検討2021
- Author(s)
  徳田昂太郎, 山中芳亮, 小杉健二, 西村春来, 塚本学, 田島貴文, 鈴木仁士, 川崎展, 内田宗志, 中村英一郎, 酒井昭典
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] 特発性手根管症候群に対するトリアムシノロンの効果発現機序　基礎および臨床双方の観点から2021
- Author(s)
  山中芳亮, 田島貴文, 辻村良賢, 小杉健二, 真野洋佑, 善家雄吉, 酒井昭典
- Organizer
  第64回日本手外科学会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] マウス膝関節拘縮モデルにおいてメトホルミンは関節拘縮を抑制する2020
- Author(s)
  徳田昂太郎, 山中芳亮, 小杉健二, 西村春来, 塚本学, 田島貴文, 鈴木仁士, 川崎展, 内田宗志, 中村英一郎, 酒井昭典
- Organizer
  第35日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K18047
[Presentation] エストラジオールが特発性手根管症候群患者の屈筋腱腱鞘滑膜内線維芽細胞に与える効果の検討2018
- Author(s)
  山中芳亮
- Organizer
  第61回日本手外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] エストラジオールが閉経後特発性手根管症候群患者の手根管内屈筋腱滑膜に与える効果2018
- Author(s)
  山中芳亮
- Organizer
  第29回日本末梢神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] エストラジオールが閉経後特発性手根管症候群患者のsubsynovial connective tissueに与える影響2018
- Author(s)
  山中芳亮
- Organizer
  第50回日本結合組織学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] The Effect of Estradiol on the Expression of Profibrotic Markers in Fibroblasts Derived from the Subsynovial Connective Tissue of Patients with Idiopathic Carpal Tunnel Syndrome2018
- Author(s)
  Yoshiaki Yamanaka
- Organizer
  Orthopaedic Research Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] 特発性手根管症候群閉経後女性患者における屈筋腱周囲滑膜内線維芽細胞にエストラジオールが与える効果の検討2018
- Author(s)
  山中芳亮
- Organizer
  第91回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] エストラジオールは閉経後特発性手根管症候群患者のsubsynovial connective tissueの線維化を抑制する2018
- Author(s)
  山中芳亮
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K16677
[Presentation] Effect of Estradiol on Fibroblasts from Idiopathic Carpal Tunnel Syndrome Patients2018
- Author(s)
  Yoshiaki Yamanaka
- Organizer
  American Society for the Surgery of the Hand Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16677

1. 蜂須賀明子 (90646936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 内田宗志 (60330990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 森本景之 (30335806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 塚本学 (70778159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田島貴文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Yamanaka Yoshiaki 山中 芳亮

Research Projects

Research Products

Co-Researchers

Elucidation of Joint contracture mechanisms focusing on adipocytokinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Involvement and the Regulatory Mechanism of Relaxin in Hip Osteoarthritis - Efforts toward Clinical Application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肘部管症候群における術中末梢神経電気刺激療法ー神経再生とBDNF遺伝子多型ー

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of tissue fibrosis mechanism associated with type 2 diabetes mouse focusing on insulin receptor substratePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of tissue fibrosis focusing on estradiolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular and Clinical Elucidation of the Mechanism of Action of Steroids in Idiopathic Carpal Tunnel Syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of a monocyte chemoattractant protein-1 synthesis inhibitor on fibroblasts from patients with carpal tunnel syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a novel knee contracture mouse model by immobilization using external fixation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of metformin treatment and its time of administration on joint capsular fibrosis induced by mouse knee immobilization2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] エストラジオールが閉経後特発性手根管症候群患者の手根管内屈筋腱滑膜に与える効果2019

Author(s)

Journal Title

Data Source

[Journal Article] Effect of estradiol on fibroblasts from postmenopausal idiopathic carpal tunnel syndrome patients2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 糖尿病モデルマウスにおける膝関節拘縮機序の検討2023

Author(s)

Organizer

Data Source

[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023

Author(s)

Organizer

Data Source

[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023

Author(s)

Organizer

Data Source

[Presentation] 糖尿病モデルマウスに対するメトホルミン投与が膝関節包に与える影響の検討2023

Author(s)

Organizer

Data Source

[Presentation] Adiponectin inhibits fibrosis of fibroblasts in the palmar aponeurosis in Dupuytren's contracture2023

Yamanaka Yoshiaki 山中芳亮

[Presentation] 特発性手根管症候群に対するトリアムシノロンの効果発現機序　基礎および臨床双方の観点から2021