Matsui Hideaki 松井秀彰

Researcher Number	60710853
Other IDs	https://orcid.org/0000-0003-4908-1035
Affiliation (Current)	2024: 新潟大学, 脳研究所, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 新潟大学, 脳研究所, 教授 2019: 新潟大学, 研究推進機構, 准教授 2018: 新潟大学, 研究推進機構, 研究教授 2017: 新潟大学, 研究推進機構, 准教授 2015 – 2016: 新潟大学, 研究推進機構超域学術院, 准教授 2013 – 2015: 宮崎大学, 医学部, 助教 2014: 宮崎大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Laboratory animal science / Neurophysiology / General neuroscience / Medium-sized Section 51:Brain sciences and related fields / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Biological Sciences Except Principal Investigator Basic Section 38060:Applied molecular and cellular biology-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator パーキンソン病 / 神経科学 / アフリカメダカ / ミトコンドリアDNA / 老化 / アルツハイマー病 / アルファシヌクレイン / アミロイド前駆タンパク質 / 加齢関連疾患 / ウイルスDNA … More / 核DNA / 異所性のDNA / 神経変性 / DNaseII / IFI16 / リソソーム / αシヌクレイン / シナプス機能 / 可視化 / シナプス / シナプス可塑性 / 神経変性疾患 … More Except Principal Investigator 自然免疫応答 / 加齢関連疾患 / DNAセンサー / 異所性DNA / ミトコンドリアDNA / 新規治療法 / 自律神経 / 非アルコール性脂肪性肝疾患 / 自律神経調節 Less

老化・疾患をもたらす各種の細胞質DNAに対するセンサーと細胞応答の比較解析
- Principal Investigator
  
  酒井晶子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Niigata University
APPとαシヌクレインの生理機能に立脚したアルツハイマーとパーキンソンのシン病態Principal Investigator
- Principal Investigator
  
  松井秀彰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  Niigata University
異所性のDNAがもたらす老化・加齢関連疾患・感染症病態の網羅的比較解析Principal Investigator
- Principal Investigator
  
  松井秀彰
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Niigata University
Application of the Autonomic Nervous Management for NAFLD Treatment
- Principal Investigator
  
  寺井崇二
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Niigata University
Neurodegeneration induced by ectopic mitochondrial DNAPrincipal Investigator
- Principal Investigator
  
  Matsui Hideaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
αシヌクレイン老化が引き起こす個体老化パーキンソン病Principal Investigator
- Principal Investigator
  
  松井秀彰
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
African killifish discloses Parkinson-like phenotypes during aging.Principal Investigator
- Principal Investigator
  
  Matsui Hideaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Niigata University
In vivo imaging of synaptic plasticityPrincipal Investigator
- Principal Investigator
  
  Matsui Hideaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Niigata University
Can short-lived African medaka be a model of neuropsychiatric disease ?Principal Investigator
- Principal Investigator
  
  Matsui Hideaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Miyazaki
小型魚類を用いたシナプス可塑性のin vivoイメージングPrincipal Investigator
- Principal Investigator
  
  松井秀彰
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  University of Miyazaki

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease.2021
- Author(s)
  Matsui, H.*, Ito, J., Matsui, N., Uechi, T., Onodera, O., Kakita, A.
- Journal Title
  
  Nat. Commun.
  
  Volume: - Issue: 1 Pages: 3101-3101
- DOI
  10.1038/s41467-021-23452-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-19H01043, KAKENHI-PROJECT-19H01061, KAKENHI-PROJECT-19K08869
[Journal Article] Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish2020
- Author(s)
  Nyuzuki Hiromi、Ito Shinji、Nagasaki Keisuke、Nitta Yohei、Matsui Noriko、Saitoh Akihiko、Matsui Hideaki
- Journal Title
  
  IBRO Reports
  
  Volume: 9 Pages: 1-8
- DOI
  10.1016/j.ibror.2020.05.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14835, KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-18J00367
[Journal Article] Esophageal High-Resolution Manometry for Diagnosing the Severity of the Chronic Intestinal Pseudo-Obstruction: A Case Series2020
- Author(s)
  Sato Hiroki、Kamimura Kenya、Matsui Hideaki、Owaki Takashi、Morita Shinichi、Tanaka Yuto、Ishikawa Natsuki、Shimada Yoshifumi、Yokoyama Junji、Wakai Toshifumi、Terai Shuji
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: - Issue: 11 Pages: 3960-3967
- DOI
  10.1007/s10620-020-06701-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08279, KAKENHI-PROJECT-20K08379, KAKENHI-PROJECT-18K15805, KAKENHI-PROJECT-21K19478
[Journal Article] 小型魚類を用いた医学研究2020
- Author(s)
  松井秀彰*
- Journal Title
  
  新潟県医師会報
  
  Volume: 10 Pages: 2-6
- Data Source
  KAKENHI-PROJECT-18H02716
[Journal Article] Shrinkage of the myenteric neurons of the small intestine in patients with multiple system atrophy2019
- Author(s)
  Ozawa Tetsutaro、Shimizu Hiroshi、Matsui Hideaki、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Autonomic Neuroscience
  
  Volume: 221 Pages: 102583-102583
- DOI
  10.1016/j.autneu.2019.102583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-19H01043
[Journal Article] Age- and α-Synuclein-Dependent Degeneration of Dopamine and Noradrenaline Neurons in the Annual Killifish Nothobranchius furzeri2019
- Author(s)
  Matsui Hideaki、Kenmochi Naoya、Namikawa Kazuhiko
- Journal Title
  
  Cell Reports
  
  Volume: 26 Issue: 7 Pages: 1727-1733.e6
- DOI
  10.1016/j.celrep.2019.01.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05692, KAKENHI-PROJECT-18H02716
[Journal Article] Parkinson’s disease pathogenesis from the viewpoint of small fish models2017
- Author(s)
  Matsui Hideaki、Takahashi Ryosuke
- Journal Title
  
  J Neural Transm
  
  Volume: 125 Issue: 1 Pages: 25-33
- DOI
  10.1007/s00702-017-1772-1
- Data Source
  KAKENHI-PUBLICLY-17H05692, KAKENHI-PROJECT-15H05571, KAKENHI-PROJECT-16K14597, KAKENHI-PROJECT-18H02716
[Journal Article] Dopamine system, cerebellum, and nucleus ruber in fish and mammals2017
- Author(s)
  Matsui Hideaki
- Journal Title
  
  Dev Growth Differ
  
  Volume: 59 Issue: 4 Pages: 219-227
- DOI
  10.1111/dgd.12357
- Data Source
  KAKENHI-PUBLICLY-17H05692, KAKENHI-PROJECT-15H05571, KAKENHI-PROJECT-16K14597
[Journal Article] An optimized method for counting dopaminergic neurons in zebrafish2017
- Author(s)
  Matsui Hideaki、Sugie Atsushi
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 9 Pages: e0184363-e0184363
- DOI
  10.1371/journal.pone.0184363
- Data Source
  KAKENHI-PUBLICLY-17H05692, KAKENHI-PROJECT-15H05571, KAKENHI-PROJECT-16K14597
[Journal Article] 生命科学を開く新しい実験動物モデル-11. 超短命脊椎動物アフリカメダカ2017
- Author(s)
  Hideaki Matsui
- Journal Title
  
  生体の科学
  
  Volume: 68 Pages: 80-84
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K14597
[Journal Article] The Use of Fish Models to Study Human Neurological Disorders2017
- Author(s)
  Hideaki Matsui
- Journal Title
  
  Neuroscience Research
  
  Volume: 16 Pages: 1-7
- DOI
  10.1016/j.neures.2017.02.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05571, KAKENHI-PROJECT-16K14597, KAKENHI-PUBLICLY-17H05692
[Journal Article] Cerebrospinal fluid injection into adult zebrafish for disease research2017
- Author(s)
  Matsui Hideaki、Matsui Noriko
- Journal Title
  
  J Neural Transm
  
  Volume: 124 Issue: 12 Pages: 1627-1633
- DOI
  10.1007/s00702-017-1787-7
- Data Source
  KAKENHI-PUBLICLY-17H05692, KAKENHI-PROJECT-16K14597
[Journal Article] Analyzing Synaptic Modulation of Drosophila melanogaster Photoreceptors after Exposure to Prolonged Light.2017
- Author(s)
  Sugie A, Möhl C, Hakeda-Suzuki S, Matsui H, Suzuki T, Tavosanis G.
- Journal Title
  
  Journal of Visual Experiments
  
  Volume: - Issue: 120
- DOI
  10.3791/55176
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06457, KAKENHI-PROJECT-15H05571
[Presentation] Neurodegeneration induced by ectopic mtDNA.2020
- Author(s)
  Matsui H.
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02716
[Presentation] Age - and α-synuclein dependent degeneration of dopamine and noradrenaline neurons in the annual killifish Nothobranchius furzeri.2019
- Author(s)
  Matsui H.
- Organizer
  第60回神経学会
- Data Source
  KAKENHI-PROJECT-18H02716
[Presentation] Age - and α-synuclein dependent degeneration of dopamine and noradrenaline neurons in the annual killifish Nothobranchius furzeri.2019
- Author(s)
  Matsui H.
- Organizer
  5th World Parkinson Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02716
[Presentation] Cytosolic dsDNA of mitochondrial origin exerts cytotoxicity and neurodegeneration in PD2019
- Author(s)
  Matsui H.
- Organizer
  第42回神経科学学会
- Data Source
  KAKENHI-PROJECT-18H02716
[Presentation] Age and alpha-synuclein dependent degeneration of dopamine neurons in the annual killifish2019
- Author(s)
  Matsui H
- Organizer
  第60回神経学会
- Data Source
  KAKENHI-PUBLICLY-17H05692
[Presentation] Age - and α-synuclein dependent degeneration of dopamine and noradrenaline neurons in the annual killifish Nothobranchius furzeri2019
- Author(s)
  Matsui H
- Organizer
  5th World Parkinson Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05692
[Presentation] Ectopic dsDNA of mitochondrial origin induces neurodegeneration. 異所性のミトコンドリアDNAが起こす神経変性.2019
- Author(s)
  Matsui H.
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02716
[Presentation] Elucidating pathogenesis of Parkinson's disease with various fish model2018
- Author(s)
  Matsui H
- Organizer
  第70回日本細胞生物学会（日本発生生物学会合同大会）
- Data Source
  KAKENHI-PUBLICLY-17H05692
[Presentation] Annual killifish, Nothobranchius furzeri, discloses Parkinson's disease phenotypes.2017
- Author(s)
  Matsui H.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05692
[Presentation] 魚のドパミン神経とパーキンソン病2017
- Author(s)
  Hideaki Matsui
- Organizer
  第6回生理研霊長研脳研合同シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター
- Year and Date
  2017-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H05571
[Presentation] Annual killifish, Nothobranchius furzeri, discloses Parkinson's disease phenotypes.2017
- Author(s)
  Hideaki Matsui
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] An Annual Killifish, Nothobranchius furzeri, Suffers From Parkinson’s Disease.2017
- Author(s)
  Matsui H.
- Organizer
  International Meeting on Non-Mammalian Models in Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05692
[Presentation] 魚のドパミン神経とパーキンソン病2017
- Author(s)
  Hideaki Matsui
- Organizer
  第6回生理研霊長研脳研合同シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター
- Year and Date
  2017-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] An Annual Killifish, Nothobranchius furzeri, Suffers From Parkinson’s Disease.2017
- Author(s)
  Hideaki Matsui
- Organizer
  International Meeting on Non-Mammalian Models in Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] Teleost fish models of Parkinson’s disease2016
- Author(s)
  Hideaki Matsui
- Organizer
  Symposium: Basal Ganglia in Health and Disease (Satellite Symposium of Neuroscience 2016)
- Place of Presentation
  PACIFICO Yokohama
- Invited
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] 小型魚類で明らかにする神経病態2016
- Author(s)
  Hideaki Matsui
- Organizer
  第46回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] 小型魚類を用いた神経疾患研究2016
- Author(s)
  Hideaki Matsui
- Organizer
  第57回神経学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-15H05571
[Presentation] 小型魚類で明らかにする神経病態2016
- Author(s)
  Hideaki Matsui
- Organizer
  第46回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-15H05571
[Presentation] Teleost fish models of Parkinson’s disease.2016
- Author(s)
  Hideaki Matsui
- Organizer
  Symposium: Basal Ganglia in Health and Disease (Satellite Symposium of Neuroscience 2016)
- Place of Presentation
  PACIFICO Yokohama
- Invited
- Data Source
  KAKENHI-PROJECT-15H05571
[Presentation] 小型魚類を用いた神経疾患研究2016
- Author(s)
  Hideaki Matsui
- Organizer
  第57回神経学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-05-18
- Invited
- Data Source
  KAKENHI-PROJECT-16K14597
[Presentation] Time course and Progression of Parkinson’s Disease in Small Fish2016
- Author(s)
  Hideaki Matsui
- Organizer
  Chronological change in Brain function Symposium
- Place of Presentation
  千葉大学
- Year and Date
  2016-03-08
- Invited
- Data Source
  KAKENHI-PROJECT-26640061

1. 垣花太一 (60746907)

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2. 渡邉香奈子 (80626094)

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3. 寺井崇二 (00332809)

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4. 上村顕也 (00579146)

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5. 上野将紀 (40435631)

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6. 酒井晶子 (70532745)

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7. 新田陽平

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8. 佐藤裕樹

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9. 鈴木崇之

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Matsui Hideaki 松井 秀彰

Research Projects

Research Products

Co-Researchers

老化・疾患をもたらす各種の細胞質DNAに対するセンサーと細胞応答の比較解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

APPとαシヌクレインの生理機能に立脚したアルツハイマーとパーキンソンのシン病態Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

異所性のDNAがもたらす老化・加齢関連疾患・感染症病態の網羅的比較解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of the Autonomic Nervous Management for NAFLD Treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neurodegeneration induced by ectopic mitochondrial DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

αシヌクレイン老化が引き起こす個体老化パーキンソン病Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

African killifish discloses Parkinson-like phenotypes during aging.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo imaging of synaptic plasticityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Can short-lived African medaka be a model of neuropsychiatric disease ?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

小型魚類を用いたシナプス可塑性のin vivoイメージングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Esophageal High-Resolution Manometry for Diagnosing the Severity of the Chronic Intestinal Pseudo-Obstruction: A Case Series2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 小型魚類を用いた医学研究2020

Matsui Hideaki 松井秀彰