Hiruta Yuki 蛭田勇樹

… Alternative Names

HIRUTA YUKI 蛭田勇樹

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Researcher Number	60710944
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 理工学部(矢上), 准教授
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 理工学部(矢上), 准教授 2023: 慶應義塾大学, 理工学部(矢上), 准教授 2018 – 2023: 慶應義塾大学, 理工学部(矢上), 講師 2022: 慶應義塾大学, 理工学部, 講師 2016: 慶應義塾大学, 薬学部(芝共立), 助教 2013 – 2015: 慶應義塾大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Complex systems / Physical pharmacy Except Principal Investigator Basic Section 42040:Laboratory animal science-related / Basic Section 34020:Analytical chemistry-related
Keywords	Principal Investigator 光熱療法 / セラノスティクス / 超分子 / トランススケールイメージング / ケージド化合物 / フリマジン誘導体 / 生物発光 / 蛍光イメージング / がん / pH応答性ポリマー … More / pH / 環境応答性高分子 / ナノ材料 / 分離精製 / 合成高分子 / ペプチドミメティクス / 抗体 / 金ナノ粒子 / イメージング / 刺激応答性ポリマー / スピロ環化平衡 / 近赤外蛍光プローブ / 細胞融合 / 筋芽細胞 / 高分子 / マウス / 細胞 / 高分子リンカー / γ-グルタミルトランスペプチダーゼ / ナノ / ドラッグデリバリーシステム / ドキソルビシン / ドラッグデリバリー / ポリマーミセル / ブロックコポリマー / 温度応答性ポリマー / 抗がん剤 / DDS / ミセル / 機能性高分子 / 温度 / がん細胞 / 細胞イメージング / 機能性蛍光プローブ / 高分子合成 / 温度応答性高分子 … More Except Principal Investigator 生物発光 / イメージング / 非侵襲 / in vivoイメージング / バイオイメージング / マイクロ流体 / 糸基板センサー / POCT / 抗体医薬品 Less

ペプチドミメティクス分子設計を基盤とした抗体及び抗体薬物複合体分離精製技術の構築Principal Investigator
- Principal Investigator
  
  蛭田勇樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
がんバイオマーカー応答性高分子を基盤とした光セラノスティクスプラットフォーム構築Principal Investigator
- Principal Investigator
  
  蛭田勇樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
がんバイオマーカー応答性高分子設計を戦略とした光セラノスティクス薬剤の開発Principal Investigator
- Principal Investigator
  
  蛭田勇樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
時空間トランススケールイメージングを可能にする超分子ケージドルシフェリンの開発Principal Investigator
- Principal Investigator
  
  蛭田勇樹
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Keio University
Development of novel bioluminescent technology
- Principal Investigator
  
  Iwano Satoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Miyazaki
  Institute of Physical and Chemical Research
Development of polymer caged luciferin enabling spatiotemporal trans-scale imagingPrincipal Investigator
- Principal Investigator
  
  蛭田勇樹
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Keio University
Development of tumor self-accumulating functionalized theranostics nanoplatformPrincipal Investigator
- Principal Investigator
  
  Hiruta Yuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Keio University
Microfluidic thread-based sensor for the detection of therapeutic antibodies in blood at point-of-care
- Principal Investigator
  
  CITTERIO Daniel
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  Keio University
Development of dual pH-responsive drug delivery career by the logical design of polymerPrincipal Investigator
- Principal Investigator
  
  Hiruta Yuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Keio University
The development of environmentally responsive fluorescence polymer probes for visualizing pathological cellsPrincipal Investigator
- Principal Investigator
  
  HIRUTA YUKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Physical pharmacy
- Research Institution
  Keio University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level2022
- Author(s)
  Orioka Mariko、Eguchi Masatoshi、Mizui Yuki、Ikeda Yuma、Sakama Akihiro、Li Qiaojing、Yoshimura Hideaki、Ozawa Takeaki、Citterio Daniel、Hiruta Yuki
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 33 Issue: 3 Pages: 496-504
- DOI
  10.1021/acs.bioconjchem.2c00035
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H00437, KAKENHI-PROJECT-20K20566, KAKENHI-PROJECT-19H00900, KAKENHI-PROJECT-19H02745, KAKENHI-PROJECT-22H00322
[Journal Article] Microfluidic thread-based analytical devices for point-of-care detection of therapeutic antibody in blood2022
- Author(s)
  Riho Shimazu, Kosuke Tomimuro, Yan Ni, Cristina Malegori, Vahid Hamedpour, Yuki Hiruta, Paolo Oliveri, Maarten Merkx, Daniel Citterio
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 352 Pages: 131002-131002
- DOI
  10.1016/j.snb.2021.131002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Journal Article] Small Molecule-Based Alkaline-Earth Metal Ion Fluorescent Probes for Imaging Intracellular and Intercellular Multiple Signals2021
- Author(s)
  Yuki Hiruta, Yutaka Shindo, Kotaro Oka, Daniel Citterio
- Journal Title
  
  Chemistry Letters
  
  Volume: - Issue: 5 Pages: 870-887
- DOI
  10.1246/cl.200917
- NAID
  130008040411
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Journal Article] Differential Effect of Azetidine Substitution in Firefly Luciferin Analogues2021
- Author(s)
  Ikeda Yuma、Orioka Mariko、Nomoto Takahiro、Hiruta Yuki、Nishiyama Nobuhiro、Citterio Daniel
- Journal Title
  
  ChemBioChem
  
  Volume: 22 Issue: 21 Pages: 3067-3074
- DOI
  10.1002/cbic.202100310
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H00437, KAKENHI-PROJECT-18H04163
[Journal Article] Long-term single cell bioluminescence imaging with C-3 position protected coelenterazine analogues2021
- Author(s)
  Mizui Yuki、Eguchi Masatoshi、Tanaka Masanobu、Ikeda Yuma、Yoshimura Hideaki、Ozawa Takeaki、Citterio Daniel、Hiruta Yuki
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 19 Issue: 3 Pages: 579-586
- DOI
  10.1039/d0ob02020f
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20566, KAKENHI-PROJECT-19H02745, KAKENHI-PUBLICLY-19H05429, KAKENHI-PLANNED-18H05410, KAKENHI-PROJECT-19H00900, KAKENHI-PROJECT-18H02008
[Journal Article] Fluorescent and Bioluminescent Probes based on Precise Molecular Design2021
- Author(s)
  KUMADA Rei、ORIOKA Mariko、CITTERIO Daniel、HIRUTA Yuki
- Journal Title
  
  BUNSEKI KAGAKU
  
  Volume: 70 Issue: 10.11 Pages: 601-616
- DOI
  10.2116/bunsekikagaku.70.601
- NAID
  130008125739
- ISSN
  0525-1931
- Year and Date
  2021-10-05
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Journal Article] Near-infrared pH responsive heptamethine cyanine platforms: Modulating the proton acceptor2020
- Author(s)
  Kurutos Atanas、Shindo Yutaka、Hiruta Yuki、Oka Kotaro、Citterio Daniel
- Journal Title
  
  Dyes and Pigments
  
  Volume: 181 Pages: 108611-108611
- DOI
  10.1016/j.dyepig.2020.108611
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18F18767, KAKENHI-PROJECT-19K16339
[Journal Article] Ring-Fused Firefly Luciferins: Expanded Palette of Near-Infrared Emitting Bioluminescent Substrates2020
- Author(s)
  Ikeda Yuma、Nomoto Takahiro、Hiruta Yuki、Nishiyama Nobuhiro、Citterio Daniel
- Journal Title
  
  Analytical Chemistry
  
  Volume: 92 Issue: 6 Pages: 4235-4243
- DOI
  10.1021/acs.analchem.9b04562
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-19J12615, KAKENHI-PROJECT-17H01215, KAKENHI-PUBLICLY-19H05429
[Journal Article] pH-Responsive Tunable Mixed-Charge Polymers for pH-Selective Interaction with Anionic Biological Constituents2020
- Author(s)
  Hiruta Yuki、Sawada Kazuki、Mizui Yuki、Citterio Daniel
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 93 Issue: 4 Pages: 547-552
- DOI
  10.1246/bcsj.20190374
- NAID
  130007831631
- Data Source
  KAKENHI-PROJECT-19K16339
[Journal Article] Thread-Based Multiplex Bioluminescent Antibody Detection in a Single Drop of Whole Blood2020
- Author(s)
  Kosuke Tomimuro, Keisuke Tenda, Yan Ni, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Journal Title
  
  ACS Sensors
  
  Volume: ー
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Journal Article] Biothiol-Activatable Bioluminescent Coelenterazine Derivative for Molecular Imaging in Vitro and in Vivo2019
- Author(s)
  Nanako Nomura, Ryo Nishihara, Takahiro Nakajima, Takahiro Nakajima, Sung Bae Kim, Naoko Iwasawa, Yuki Hiruta, Shigeru Nishiyama, Moritoshi Sato, Daniel Citterio, Koji Suzuki
- Journal Title
  
  Anal. Chem.
  
  Volume: 91(15) Issue: 15 Pages: 9546-9553
- DOI
  10.1021/acs.analchem.9b00694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KK0029, KAKENHI-PROJECT-17H01215, KAKENHI-PUBLICLY-19H05429
[Journal Article] Paper-Based Antibody Detection Devices Using Bioluminescent BRET-Switching Sensor Proteins2018
- Author(s)
  Tenda Keisuke、van Gerven Benice、Arts Remco、Hiruta Yuki、Merkx Maarten、Citterio Daniel
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 47 Pages: 15369-15373
- DOI
  10.1002/anie.201808070
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Journal Article] Microfluidic thread-based analytical devices for antibody detection in whole blood using bioluminescent sensor proteins2018
- Author(s)
  Tomimuro Kosuke, Tenda Keisuke, Hiruta Yuki, Merkx Maarten, Citterio Daniel
- Journal Title
  
  Proceedings of MicroTAS 2018
  
  Volume: なし Pages: 1018-1021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Journal Article] Design and synthesis of temperature-responsive polymer/silica hybrid nanoparticles and application to thermally controlled cellular uptake2017
- Author(s)
  Yuki Hiruta, Ryo Nemoto, and Hideko Kanazawa
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces
  
  Volume: 153 Pages: 2-9
- DOI
  10.1016/j.colsurfb.2017.01.052
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18846, KAKENHI-PROJECT-16H05083
[Journal Article] pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting2015
- Author(s)
  Yuki Hiruta, Takaaki Funatsu, Yutaro Maekawa, Minami Matsuura, Teruo Okano, and Hideko Kanazawa
- Journal Title
  
  CRS Newsletter
  
  Volume: 32 Pages: 10-11
- Data Source
  KAKENHI-PROJECT-25893232
[Journal Article] pH/temperature-responsive fluorescence polymer probe with pH-controlled cellular uptake2015
- Author(s)
  Y. Hiruta, T. Funatsu, M. Matsuura, J. Wang, E. Ayano, H. Kanazawa
- Journal Title
  
  Sensors and Actuators B
  
  Volume: 207 Pages: 724-731
- DOI
  10.1016/j.snb.2014.10.065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670081, KAKENHI-PROJECT-25893232
[Journal Article] Design of Environmentally Responsive Fluorescent Polymer Probes for Cellular Imaging2015
- Author(s)
  Arisa Yamada, Yuki Hiruta, Jian Wang, Eri Ayano, Hideko Kanazawa
- Journal Title
  
  Biomacromolecules
  
  Volume: 16 Issue: 8 Pages: 2356-2362
- DOI
  10.1021/acs.biomac.5b00591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18846
[Journal Article] Temperature-Responsive Fluorescence Polymer Probes with Accurate Thermally Controlled Cellular Uptakes2014
- Author(s)
  Y. Hiruta, M. Shimamura, M. Matsuura, Y. Maekawa, T. Funatsu, Y. Suzuki, E. Ayano, T. Okano, H. Kanazawa
- Journal Title
  
  ACS Macro Lett.
  
  Volume: 3 Issue: 3 Pages: 281-285
- DOI
  10.1021/mz5000569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670081, KAKENHI-PROJECT-25893232
[Patent] アミノ酸誘導体蛍光ポリマー及びそれを利用した蛍光プローブ2014
- Inventor(s)
  金澤秀子、蛭田勇樹
- Industrial Property Rights Holder
  金澤秀子、蛭田勇樹
- Industrial Property Rights Type
  特許
- Filing Date
  2014-03-26
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 時空間トランススケールイメージングを可能にする新規生物発光基質の開発2023
- Author(s)
  蛭田勇樹
- Organizer
  新学術領域研究「シンギュラリティ生物学」成果報告シンポジウム・領域会議
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] ホスフィン酸リガンドを有する蛍光プローブの開発と細胞イメージングへの応用2023
- Author(s)
  熊田怜、蛭田勇樹
- Organizer
  新学術領域研究「シンギュラリティ生物学」成果報告シンポジウム・領域会議
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間の発光イメージングを可能にする生物発光基質フリマジン誘導体の開発2022
- Author(s)
  蛭田勇樹、織岡真理子、江口正敏、水井侑希、池田裕真、 Qiaojing Li、吉村英哲、小澤岳昌、ダニエルチッテリオ
- Organizer
  公益社団法人日本顕微鏡学会第78回学術講演会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間の発光イメージングを可能にする生物発光基質の開発と筋芽細胞融合の長期観察への応用2022
- Author(s)
  蛭田勇樹、織岡真理子、江口正敏、水井侑希、池田裕真、 Qiaojing Li、吉村英哲、小澤岳昌、ダニエル・チッテリオ
- Organizer
  日本分析化学会第71年会
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間発光イメージング実現のための新規セレンテラジンh誘導体の開発2022
- Author(s)
  浦野圭世、織岡真理子、チッテリオダニエル、蛭田勇樹
- Organizer
  第12回CSJ化学フェスタ2022
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] Development of caged luciferin enabling spatiotemporal trans-scale imaging2022
- Author(s)
  蛭田勇樹
- Organizer
  第60回日本生物物理学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] Basic evaluation of bioluminescent furimazine derivatives for sensitive and long-term bioimaging2021
- Author(s)
  Orioka Mariko, Mizui Yuki, Eguchi Masatoshi, Ikeda Yuma, Yoshimura Hideaki, Ozawa Takeaki, Citterio Daniel, Hiruta Yuki
- Organizer
  Royal Society of Chemistry Tokyo International Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間イメージングへの応用を目指した新規生物発光基質フリマジン誘導体2021
- Author(s)
  織岡真理子, 水井侑希, 江口正敏, 池田裕真, 吉村英哲, 小澤岳昌, ダニエル・チッテリオ, 蛭田勇樹
- Organizer
  生物発光化学発光研究会第36回学術講演会
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間・高感度のバイオイメージングを目指した生物発光基質フリマジン誘導体の開発2021
- Author(s)
  織岡真理子、水井侑希、江口正敏、池田裕真、吉村英哲、小澤岳昌、チッテリオダニエル、蛭田勇樹
- Organizer
  日本化学会第101春季年会（2021）
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Development of caged luciferin enabling spatiotemporal trans-scale imaging2021
- Author(s)
  Yuki Hiruta, Mariko Orioka, Yuki Mizui, Masatoshi Eguchi, Yuma Ikeda, Hideaki Yoshimura, Takeaki Ozawa, Daniel Citterio
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] Development of stable and water soluble furimazine analogues for high sensitive and long-term bioluminescencei Imaging2021
- Author(s)
  Orioka Mariko, Mizui Yuki, Eguchi Masatoshi, Ikeda Yuma, Yoshimura Hideaki, Ozawa Takeaki, Citterio Daniel, Hiruta Yuki
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 生物発光基質フリマジン誘導体の基礎特性評価と長時間細胞イメージングへの応用2021
- Author(s)
  織岡真理子, 水井侑希, 江口正敏, 池田裕真, 吉村英哲, 小澤岳昌, ダニエル・チッテリオ, 蛭田勇樹
- Organizer
  日本化学会秋季事業第11回CSJ化学フェスタ2021
- Data Source
  KAKENHI-PUBLICLY-21H00437
[Presentation] 長時間・高感度のバイオイメージングを目指した新規Caged Furimazineの開発2020
- Author(s)
  織岡真理子、水井侑希、江口正敏、池田裕真、吉村英哲、小澤岳昌、チッテリオダニエル、蛭田勇樹
- Organizer
  第10回CSJ化学フェスタ2020
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Ring-Fused Firefly Luciferins: Expanded Palette of Structure-Inherent Near-infrared Emitting Bioluminescent Substrates2020
- Author(s)
  Yuma Ikeda, Takahiro Nomoto, Yuki Hiruta, Nobuhiro Nishiyama, Daniel Citterio
- Organizer
  PITTCON 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] 長時間バイオイメージングのための安定生物発光基質フリマジン誘導体の開発2019
- Author(s)
  水井侑希, 池田裕真, 江口正敏, 吉村英哲, 小澤岳昌, チッテリオダニエル, 蛭田勇樹
- Organizer
  生物発光研究会第35回学術講演会
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Microfluidic Thread-Based Analytical Devices for Point-of-Care Detection of Therapeutic Antibodies in Blood2019
- Author(s)
  Riho Shimazu, Kosuke Tomimuro, Yan Ni, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Organizer
  日本分析化学会第68年会
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] Single-Step Bioluminescence Lateral Flow Immunoassays for Diagnostics2019
- Author(s)
  Riho Shimazu, Junnosuke Kawahara, Kosuke Tomimuro, Kazushi Misawa, Yan Ni, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Organizer
  23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] バイオイメージングのための高S/N比・長時間発光基質フリマジン誘導体の開発2019
- Author(s)
  水井侑希, 池田裕真, 蛭田勇樹, チッテリオダニエル
- Organizer
  日本分析化学会第68年会
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Development of temperature-responsive polymer materials for cancer therapy and imaging2019
- Author(s)
  Yuki Hiruta, Kazuki Sawada, Kento Kannaka, Haruka Miura, Kohei Sano, Takahiro Mukai, Daniel Citterio
- Organizer
  The 2019 Controlled Release Society Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16339
[Presentation] Microfluidic Thread-Based Analytical Devices for Point-of-Care Detection of Therapeutic Antibodies in Blood2019
- Author(s)
  Riho Shimazu, Kosuke Tomimuro, Yan Ni, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Organizer
  RSC Tokyo International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] pH-Responsive mixed-charge polymer for weak acidic tumorous environment selective cellular uptake2019
- Author(s)
  Yuki Hiruta, Kazuki Sawada, Daniel Citterio
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K16339
[Presentation] 抗体検出のための生物発光タンパク質を用いたマイクロ流体糸基板型分析デバイスの開発2019
- Author(s)
  Kosuke Tomimuro, Keisuke Tenda, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Organizer
  日本分析化学会関東支部若手交流会
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] Paper- and thread-based immunoassay devices with colorimetric bioluminescence signaling2019
- Author(s)
  Tomimuro Kosuke, Tenda Keisuke, Merkx Maarten, Hiruta Yuki, Citterio Daniel
- Organizer
  Pittcon 2019, Philadelphia, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] 生体分析応用に向けた合成ホタル生物発光基質誘導体2019
- Author(s)
  池田裕真, 野本貴大, 蛭田勇樹, 西山伸宏, チッテリオダニエル
- Organizer
  日本分析化学会関東支部若手交流会
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Thread-Based Analytical Device for Antibody Detection in Whole Blood by Using Bioluminescent Sensor Proteins2019
- Author(s)
  Kosuke Tomimuro, Keisuke Tenda, Yuki Hiruta, Maarten Merkx, Daniel Citterio
- Organizer
  RSC Tokyo International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] 環融合戦略を基盤とした近赤外発光ホタルルシフェリン誘導体群の創製2019
- Author(s)
  池田裕真, 野本貴大, 蛭田勇樹, 西山伸宏, チッテリオダニエル
- Organizer
  第３５回生物発光化学発光研究会
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] pH-response tunable mixed-charged polymers for reversible adsorption and desorption of proteins2019
- Author(s)
  Yuki Hiruta, Kazuki Sawada, Taisei Kaku, Yuki Tokura, Seimei Shiratori, Daniel Citterio
- Organizer
  ACS Fall 2019 National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16339
[Presentation] Structure-luminescence relationship of near-infrared firefly luciferin analogues2019
- Author(s)
  Yuma Ikeda, Takahiro Nomoto, Yuki Hiruta, Nobuhiro Nishiyama, Daniel Citterio
- Organizer
  The ACS Fall 2019 National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Development of Stable Bioluminescent Furimazine Derivatives for long-term and high S/N ratio imaging2019
- Author(s)
  Yuki Mizui, Masanobu Tanaka, Naoko Iwasawa, Yuki Hiruta, Daniel Citterio
- Organizer
  CRS Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05429
[Presentation] Microfluidic thread-based analytical devices for antibody detection in whole blood using bioluminescent sensor proteins2018
- Author(s)
  Tomimuro Kosuke, Tenda Keisuke, Hiruta Yuki, Merkx Maarten, Citterio Daniel
- Organizer
  International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] Development of stable bioluminescent substrates activatable by hydrolysis2018
- Author(s)
  Mizui Yuki, Tanaka Masanobu, Tenda Keisuke, Iwasawa Naoko, Hiruta Yuki, Citterio Daniel
- Organizer
  Royal Society of Chemistry - Tokyo International Conference 2018 (RSC-TIC 2018), Makuhari Messe, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] Paper-based analytical device for the detection of antibodies in biological samples2018
- Author(s)
  Tenda Keisuke、van Gerven Benice、Arts Remco、Hiruta Yuki、Merkx Maarten、Citterio Daniel
- Organizer
  PERCH-CIC 2018, Pattaya, Thailand
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02008
[Presentation] 診断技術への応用を目指したスマートポリマープローブの精密設計2017
- Author(s)
  蛭田勇樹
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 温度応答性有機・無機ハイブリッドポリマーナノ粒子の開発2016
- Author(s)
  蛭田勇樹、小出さやか、根本遼、金澤秀子
- Organizer
  第２５回インテリジェント材料／システムシンポジウム
- Place of Presentation
  東京女子医科大学（東京都・新宿区）
- Year and Date
  2016-01-08
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] がんの診断・治療を目指したpH応答性高分子の精密合成2016
- Author(s)
  蛭田勇樹
- Organizer
  第６０回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都・文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Temperature-resopnsive fluorescence polymer nanoparticles with thermally controlled cellular uptakes2016
- Author(s)
  Yuki Hiruta, Ryo Nemoto, Yuki Nagata, and Hideko Kanazawa
- Organizer
  2016 CRS Annual Meeting & Exposition
- Place of Presentation
  Washington State Convention Center, Seattle, USA
- Year and Date
  2016-07-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Tumor acidity sensitive polymeric micelle for selective cellular uptake of doxorubicin2016
- Author(s)
  Yuki Hiruta, Yuki Nagata, Ryo Nemoto, and Hideko Kanazawa
- Organizer
  2016 CRS Annual Meeting & Exposition
- Place of Presentation
  Washington State Convention Center, Seattle, USA
- Year and Date
  2016-07-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 固形がん選択的ターゲティングを目指したpH応答性高分子ミセルの創製2016
- Author(s)
  永田勇貴、山田有紗、根本遼、蛭田勇樹、金澤秀子
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Dual pH-resopnsive polymeric micelle for tumor cell selective uptake of anti-tumor agent2016
- Author(s)
  Yuki Hiruta, Yuki Kanda, Atsushi Miki, Yuki Nagata, and Hideko Kanazawa
- Organizer
  3rd International Conference on Biomaterials Science in Tokyo
- Place of Presentation
  University of Tokyo, Japan
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Temperature/pH-responsive Polymer Nanomaterials for Therapeutics and Diagnostics2016
- Author(s)
  Yuki Hiruta, and Hideko Kanazawa
- Organizer
  EMN Meeting on Hydrogel Materials
- Place of Presentation
  Peninsula Excelsior Hotel, Singapore
- Year and Date
  2016-05-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 温度応答性ポリマーナノ粒子の開発と温度応答性細胞取り込みの評価2016
- Author(s)
  蛭田勇樹、小出さやか、根本遼、金澤秀子
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 温度応答性ポリマーナノ粒子の創製と温度による細胞取り込み制御2016
- Author(s)
  蛭田勇樹、根本遼、金澤秀子
- Organizer
  第６５回高分子学会年次大会
- Place of Presentation
  神戸コンベンションセンター（兵庫県・神戸市）
- Year and Date
  2016-05-25
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 固形がん選択的ターゲティングを目指したpH応答性ポリマーミセルの創製とpH選択的細胞取り込みの評価2016
- Author(s)
  蛭田勇樹、永田勇貴、根本遼、金澤秀子
- Organizer
  第３２回日本DDS学会学術集会
- Place of Presentation
  静岡県コンベンションツアーツセンター（静岡県・静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] pH-Responsive Polymer Nanomedicine for Acidic tumor Targeting2016
- Author(s)
  Yuki Hiruta, Yuki Nagata, Ryo Nemoto, and Hideko Kanazawa
- Organizer
  International Nanomedicine Conference
- Place of Presentation
  Hilton Mauritius Resorts & SPA, Flic-en-Flac, Mauritius
- Year and Date
  2016-08-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] pH- and temperature-responsive organic-inorganic hybrid polymer nanoparticles with controlled cellular uptake2015
- Author(s)
  Yuki Hiruta, Sayaka Koide, Jian Wang, Hideko Kanazawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Oahu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] シリカブロックコポリマーを用いた温度応答型ハイブリット蛍光なの粒子の開発2015
- Author(s)
  小出さやか、王堅、蛭田勇樹、金澤秀子
- Organizer
  第７５回分析化学討論会
- Place of Presentation
  山梨大学（山梨県・山梨市）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Development of fluorescence probe for cellular imaging utilizing a temperature-responsive polymer2015
- Author(s)
  Arisa Yamada, Jian Wang, Yuki Hiruta, Hideko Kanazawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Oahu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Development of Thermoresponsive Hybrid Nanoparticles Using Silica-block-copolymer2015
- Author(s)
  Sayaka Koide, Jian Wang, Yuki Hiruta, Hideko Kanazawa
- Organizer
  RSC Tokyo International Conference 2015
- Place of Presentation
  Makuhari (Japan)
- Year and Date
  2015-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] Preparation and characterization of thermo-responsive polymer modified liposomes aimed at application to anticancer agent delivery2015
- Author(s)
  Ryo Nemoto, Jian Wang, Yuki Hiruta, Eri Ayano, Yoshie Maitani, Hideko Kanazawa
- Organizer
  Pacifichem2015
- Place of Presentation
  Oahu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] 病態細胞の可視化を目指した温度・pH応答性蛍光ポリマープローブの開発2015
- Author(s)
  蛭田勇樹、舟津孝明、王堅、小出さやか、金澤秀子
- Organizer
  PPF2015
- Place of Presentation
  長崎ホテル清風（長崎県・長崎市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K18846
[Presentation] pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting2014
- Author(s)
  Yuki Hiruta, Takaaki Funatsu, Yutaro Maekawa, Minami Matsuura, Teruo Okano, and Hideko Kanazawa
- Organizer
  41st Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Chicago (USA)
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] がんイメージングを目指したpH・温度応答性蛍光ポリマープローブの開発2014
- Author(s)
  蛭田勇樹、舟津孝明、松浦みなみ、前川祐太朗、岡野光夫、金澤秀子
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] The development of pH-responsive fluorescence polymer probes for selective imaging of acidic tumor microenvironment2014
- Author(s)
  Yuki Hiruta, Kazuki Sakata, Kohei Okubo, Chuhei Yamamoto, Teruo Okano, Hideko Kanazawa
- Organizer
  EUROPT(R)ODE Ⅻ
- Place of Presentation
  Athens (Greece)
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 細胞可視化を目指した環境応答型蛍光プローブ2014
- Author(s)
  松浦みなみ、蛭田勇樹、舟津孝明、前川祐太朗、金澤秀子、岡野光夫
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] DEVELOPMENT OF NOVEL SOLID-PHASE EXTRACTION CARTRIDGE UTILIZAING THERMO-RESPONSIVE POLYMER MODIFIED SATIONARY PHASE2013
- Author(s)
  utaro Maekawa, Yuichi Suzuki, Minami Matsuura, Takaaki Funatsu, Yuki Hiruta, Teruo Okano, Hideko Kanazawa
- Organizer
  Royal Society of Chemistry (RSC) Tokyo International Conference
- Place of Presentation
  Chiba (Japan)
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] Novel Solid-Phase Extraction Cartridge Utilizing Temperature-Responsive Polymer Modified Stationary Phase2013
- Author(s)
  Yuki Hiruta, Kazuki Sakata, Kohei Okubo, Chuhei Yamamoto, Teruo Okano, Hideko Kanazawa
- Organizer
  40th International Symposium on High Performance Liquid Phase Separations and Related Techniques
- Place of Presentation
  Tasmania (Australia)
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 生体可視化蛍光プローブへの適用を目指した環境応答型高分子の特性評価2013
- Author(s)
  鈴木優一、舟津孝明、松浦みなみ、蛭田勇樹、金澤秀子
- Organizer
  日本分析化学第６２年会
- Place of Presentation
  近畿大学
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] アミノ酸誘導体を用いた細胞膜親和性環境応答性蛍光高分子の開発2013
- Author(s)
  前川祐太郎、松浦みなみ、舟津孝明、鈴木優一、蛭田勇樹、金澤秀子
- Organizer
  第57回　日本薬学会関東支部大会
- Place of Presentation
  帝京大学
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 環境応答型高分子の特性を用いた生体可視化蛍光プローブの設計2013
- Author(s)
  鈴木優一、舟津孝明、松浦みなみ、蛭田勇樹、金澤秀子
- Organizer
  第57回　日本薬学会関東支部大会
- Place of Presentation
  帝京大学
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 病態細胞の可視化を目指した温度応答性蛍光ポリマープローブの開発2013
- Author(s)
  蛭田勇樹, 松浦みなみ, 前川祐太朗, 鈴木優一, 舟津孝明, 岡野光夫, 金澤秀子
- Organizer
  日本分析化学第６２年会
- Place of Presentation
  近畿大学
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] がんイメージングを目指したpH・温度応答性蛍光ポリマーの開発2013
- Author(s)
  舟津孝明、前川祐太朗、松浦みなみ、蛭田勇樹、金澤秀子
- Organizer
  第57回　日本薬学会関東支部大会
- Place of Presentation
  帝京大学
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting
- Author(s)
  Yuki Hiruta, Takaaki Funatsu, Minami Matsuura, Teruo Okano, and Hideko Kanazawa
- Organizer
  RSC Tokyo International Conference 2014
- Place of Presentation
  Makuhari (Japan)
- Year and Date
  2014-09-03 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting
- Author(s)
  Yuki Hiruta, Takaaki Funatsu, Yutaro Maekawa, Minami Matsuura, Teruo Okano, and Hideko Kanazawa
- Organizer
  41st annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Chicago (USA)
- Year and Date
  2014-07-13 – 2014-07-16
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] がん細胞の可視化を目指したpH応答性蛍光ポリマープローブの開発
- Author(s)
  蛭田勇樹、舟津孝明、松浦みなみ、王堅、石川裕貴、岡野光夫、金澤秀子
- Organizer
  日本分析化学会第６３年会
- Place of Presentation
  広島大学
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] The Development of pH-Responsive Fluorescence Polymer Probes for Selective Imaging of Acidic Tumor Microenvironment
- Author(s)
  Yuki Hiruta, Takaaki Funatsu, Minami Matsuura, Teruo Okano, and Hideko Kanazawa
- Organizer
  EUROPT(R)ODE Ⅻ
- Place of Presentation
  Athens (Greece)
- Year and Date
  2014-04-13 – 2014-04-16
- Data Source
  KAKENHI-PROJECT-25893232
[Presentation] 固形がん選択的ターゲティングを目指したpH/温度応答性ポリマーの創製とpH応答性細胞取り込みの評価
- Author(s)
  蛭田勇樹、舟津孝明、松浦みなみ、王堅、石川裕貴、岡野光夫、金澤秀子
- Organizer
  第３０回日本DDS学会
- Place of Presentation
  慶應義塾大学
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25893232

1. CITTERIO Daniel (00458952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. Iwano Satoshi (10734832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KANAZAWA Hideko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. YOSHIMURA Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. KURUTOS ATANAS

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 野本貴大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 金誠培

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hiruta Yuki 蛭田 勇樹

HIRUTA YUKI 蛭田 勇樹

Research Projects

Research Products

Co-Researchers

ペプチドミメティクス分子設計を基盤とした抗体及び抗体薬物複合体分離精製技術の構築Principal Investigator

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がんバイオマーカー応答性高分子を基盤とした光セラノスティクスプラットフォーム構築Principal Investigator

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がんバイオマーカー応答性高分子設計を戦略とした光セラノスティクス薬剤の開発Principal Investigator

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時空間トランススケールイメージングを可能にする超分子ケージドルシフェリンの開発Principal Investigator

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Development of novel bioluminescent technology

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Development of polymer caged luciferin enabling spatiotemporal trans-scale imagingPrincipal Investigator

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Development of tumor self-accumulating functionalized theranostics nanoplatformPrincipal Investigator

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Microfluidic thread-based sensor for the detection of therapeutic antibodies in blood at point-of-care

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Development of dual pH-responsive drug delivery career by the logical design of polymerPrincipal Investigator

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The development of environmentally responsive fluorescence polymer probes for visualizing pathological cellsPrincipal Investigator

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[Journal Article] A Series of Furimazine Derivatives for Sustained Live-Cell Bioluminescence Imaging and Application to the Monitoring of Myogenesis at the Single-Cell Level2022

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[Journal Article] Microfluidic thread-based analytical devices for point-of-care detection of therapeutic antibody in blood2022

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[Journal Article] Small Molecule-Based Alkaline-Earth Metal Ion Fluorescent Probes for Imaging Intracellular and Intercellular Multiple Signals2021

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NAID

Hiruta Yuki 蛭田勇樹

HIRUTA YUKI 蛭田勇樹