Horie Masanobu 堀江正信

Researcher Number	60727014
Other IDs
Affiliation (Current)	2025: 京都大学, 環境安全保健機構, 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 京都大学, 環境安全保健機構, 助教
Review Section/Research Field	Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related Except Principal Investigator Basic Section 27040:Biofunction and bioprocess engineering-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 63020:Radiation influence-related / Biofunction/Bioprocess
Keywords	Principal Investigator 物理刺激 / メカノプロセス / バイオリアクター / 軟培養面 / 細胞製造 / 大量培養 / 生物化学工学 / ヒトiPS細胞 / メカノバイオロジー / 幹細胞 … More / メカニカルメモリ / ヒト多能性幹細胞 / 分化誘導 / 細胞治療 / 磁性ナノ粒子 / 局所物理刺激 / メカノカルチャー / バイオプロセス / デバイス / メカノトランスダクション / 電場 / ヒト幹細胞 / ヒト多能性幹細胞細胞 / 培養プロセス / 骨格筋 / 自己組織化 / ティッシュエンジニアリング … More Except Principal Investigator 磁性ナノ粒子 / MRI / MPCポリマー / ドラッグデリバリーシステム / がん診断 / がん治療 / 温熱療法 / 人工多能性細胞 / 細胞融合 / 機能強化 / 人工多能性幹細胞 / ES細胞 / アルファ線 / 放射線影響 / PHITS / CR-39 / アポトーシス / シングルセル / ライブイメージング / バイスタンダー効果 / DNA損傷修復 / DNA二本鎖切断 / 高LET放射線 / α線 / 細胞照射 / 薬剤スクリーニング / iPS細胞 / 骨格筋 / ティッシュエンジニアリング Less

メカニカルメモリ由来細胞挙動時間遅延性の理解とメカノプロセス創成に向けた基盤研究Principal Investigator
- Principal Investigator
  
  堀江正信
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kyoto University
Development of functional magnetic nanoparticle for cancer theranostics
- Principal Investigator
  
  井藤彰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Nagoya University
メカノセンサー標的型磁性ナノ粒子の創製とヒトiPS細胞精密挙動制御技術の開発Principal Investigator
- Principal Investigator
  
  堀江正信
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kyoto University
Preparation of induced pluripotent stem cells through functional enhancement of ES cells
- Principal Investigator
  
  Kawamoto Takuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University
Evaluation of the internal exposure effect in by the single cell - alpha particle Irradiation live imaging system.
- Principal Investigator
  
  Tsunoyama Yuichi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyoto University
Basic research on the creation of innovative human iPS cell culture processes using complex physical stimulation.Principal Investigator
- Principal Investigator
  
  Horie Masanobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Kyoto University
Skeletal muscle tissue engineering using human iPS cells
- Principal Investigator
  
  Ito Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Nagoya University
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 骨格筋社会を核とした筋スマート社会2019
- Author(s)
  堀江正信、櫻井英俊
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-18K14063
[Journal Article] Bone morphogenetic protein signaling inhibitor improves differentiation and function of 3D muscle construct fabricated using C2C122024
- Author(s)
  Ding Ran、Xi Yuan、Ito Akira、Shimizu Kazunori、Nagamori Eiji、Fujita Hideaki、Kawamoto Takuo、Horie Masanobu
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: - Issue: 6 Pages: 480-486
- DOI
  10.1016/j.jbiosc.2024.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K04787, KAKENHI-PROJECT-21K19905
[Journal Article] Progress of Endogenous and Exogenous Nanoparticles for Cancer Therapy and Diagnostics2023
- Author(s)
  Fujita Hideaki、Ohta Seiichi、Nakamura Noriko、Somiya Masaharu、Horie Masanobu
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 2 Pages: 259-259
- DOI
  10.3390/genes14020259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04787, KAKENHI-PROJECT-21H01722, KAKENHI-PLANNED-21H05092
[Journal Article] Effective magnetic hyperthermia induced by mitochondria-targeted nanoparticles modified with triphenylphosphonium-containing phospholipid polymers2023
- Author(s)
  Kaneko, Masahiro; Yamazaki, Hiroto; Horie, Masanobu; Ito, Akira; Ono, Takahiro
- Journal Title
  
  Cancer Science
  
  Volume: 9 Issue: 9 Pages: 3750-3758
- DOI
  10.1111/cas.15895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04787, KAKENHI-PROJECT-21K14469
[Journal Article] Recent advances in animal cell technologies for industrial and medical applications2022
- Author(s)
  Horie Masanobu、Yamano-Adachi Noriko、Kawabe Yoshinori、Kaneoka Hidenori、Fujita Hideaki、Nagamori Eiji、Iwai Ryosuke、Sato Yasushi、Kanie Kei、Ohta Seiichi、Somiya Masaharu、Ino Kosuke
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: - Issue: 6 Pages: 509-514
- DOI
  10.1016/j.jbiosc.2022.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H01722, KAKENHI-PROJECT-20K22489, KAKENHI-PROJECT-21K04787, KAKENHI-PROJECT-21K04788, KAKENHI-PROJECT-20K05226, KAKENHI-PLANNED-21H05092
[Journal Article] Nanowarming of vitrified pancreatic islets as a cryopreservation technology for transplantation2022
- Author(s)
  Wakabayashi Taisei、Kaneko Masahiro、Nakai Tomoki、Horie Masanobu、Fujimoto Hiroyuki、Takahashi Masazumi、Tanoue Shota、Ito Akira
- Journal Title
  
  Bioengineering & Translational Medicine
  
  Volume: e10416 Issue: 4 Pages: 1-12
- DOI
  10.1002/btm2.10416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04787
[Journal Article] Pressure-induced changes on the morphology and gene expression in mammalian cells2021
- Author(s)
  Okamoto K, Watanabe TM, Horie M, Nishiyama M, Harada Y, Fujita H
- Journal Title
  
  Biology Open
  
  Volume: 10 Issue: 7
- DOI
  10.1242/bio.058544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02566, KAKENHI-PLANNED-20H05785, KAKENHI-PROJECT-21K04787
[Journal Article] A Novel Method for Polyacrylamide Gel Preparation Using N-hydroxysuccinimide-acrylamide Ester to Study Cell-Extracellular Matrix Mechanical Interactions2021
- Author(s)
  Kumai Jun、Sasagawa Satoru、Horie Masanobu、Yui Yoshihiro
- Journal Title
  
  Frontiers in Materials
  
  Volume: 8 Pages: 637278-637278
- DOI
  10.3389/fmats.2021.637278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-18K14063
[Journal Article] Effect of hydrogen peroxide concentration on the maintenance and differentiation of cultured skeletal muscle cells.2021
- Author(s)
  Hideaki Fujita, Keisuke Mae, Kouki Nagatani, Masanobu Horie, Eiji Nagamori
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 131 Issue: 5 Pages: 572-578
- DOI
  10.1016/j.jbiosc.2020.12.010
- NAID
  40022568974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K04856, KAKENHI-PROJECT-18K14063, KAKENHI-PROJECT-21K04800
[Journal Article] The effect of cell-extracellular matrix interaction on myogenic characteristics and artificial skeletal muscle tissue.2020
- Author(s)
  Masanobu Horie, Ran Ding, Sumire Nagasaka, Saki Ohsumi, Kazunori Shimizu, Hiroyuki Honda, Eiji NAGAMORI, Hideaki Fujita, Takuo Kawamoto
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: in press Issue: 1 Pages: 98-105
- DOI
  10.1016/j.jbiosc.2020.02.008
- NAID
  40022293633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K04856, KAKENHI-PROJECT-18K14063
[Journal Article] The effect of cell-extracellular matrix interaction on myogenic characteristics and artificial skeletal muscle tissue2020
- Author(s)
  Ran Ding, Masanobu Horie, Sumire Nagasaka, Saki Ohsumi, Kazunori Shimizu, Hiroyuki Honda, Eiji Nagamori, Hideaki Fujita, Takuo Kawamoto
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: In press
- NAID
  40022293633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14063
[Journal Article] Neural differentiation of mouse induced pluripotent stem cells using cadherin gene-engineered PA6 feeder cells.2019
- Author(s)
  Paerhati P, Ito A, Yoshioka K, Iwamoto K, Fujiwara S, Horie M, Kawabe Y, Kamihira M.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 印刷中 Issue: 5 Pages: 633-640
- DOI
  10.1016/j.jbiosc.2018.10.009
- NAID
  40021891674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03469
[Journal Article] Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide2019
- Author(s)
  Madhu Malinee, Alok Kumar, Takuya Hidaka, Masanobu Horie, Kouichi Hasegawa, Ganesh N Pandian, Hiroshi Sugiyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 28 Issue: 3 Pages: 115248-115248
- DOI
  10.1016/j.bmc.2019.115248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14063, KAKENHI-PROJECT-18H03530, KAKENHI-PROJECT-19H03349, KAKENHI-PROJECT-18J21755, KAKENHI-PROJECT-16H06356
[Journal Article] Inkjet micropatterning through horseradish peroxidase-mediated hydrogelation for controlled cell immobilization and microtissue fabrication2019
- Author(s)
  Gantumur, Enkhtuul, Kimura, Miyu, Taya, Masahito, Horie, Masanobu, Nakamura, Makoto, Sakai, Shinji
- Journal Title
  
  Biofacrication
  
  Volume: 12 Issue: 1 Pages: 011001-011001
- DOI
  10.1088/1758-5090/ab3b3c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14063, KAKENHI-PROJECT-17H03472, KAKENHI-PROJECT-18H01797
[Journal Article] Linking substrate and nucleus via actin cytoskeleton in pluripotency maintenance of mouse embryonic stem cells2019
- Author(s)
  David Brit Gracy、Fujita Hideaki、Yasuda Kyota、Okamoto Kazuko、Panina Yulia、Ichinose Junya、Sato Osamu、Horie Masanobu、Ichimura Taro、Okada Yasushi、Watanabe Tomonobu M
- Journal Title
  
  Stem Cell Research
  
  Volume: 41 Pages: 101614-101614
- DOI
  10.1016/j.scr.2019.101614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16259, KAKENHI-PROJECT-19H03168, KAKENHI-PUBLICLY-18H04749, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795, KAKENHI-PROJECT-18K14063
[Presentation] 細胞-基質間接着制御による高効率ヒトiPS細胞由来骨格筋誘導法の開発2024
- Author(s)
  袁茜、川本卓男、堀江正信
- Organizer
  第23 回日本再生医療学会大会
- Data Source
  KAKENHI-PROJECT-21K19905
[Presentation] ヒトiPS細胞の未分化維持培養における物理環境制御によるサイトカイン低減化への試み2023
- Author(s)
  堀江　正信, 藤田　英明
- Organizer
  第22回再生医療学会大会
- Data Source
  KAKENHI-PROJECT-21K04787
[Presentation] 軟培養面はヒト iPS 細胞培養における未分化維持を促進する2022
- Author(s)
  堀江　正信, 藤田　英明
- Organizer
  生物工学若手研究者の集い夏のオンラインセミナー2022
- Data Source
  KAKENHI-PROJECT-21K04787
[Presentation] 物理環境制御によるヒトiPS細胞の低コスト培養への試み2022
- Author(s)
  堀江　正信, 藤田　英明
- Organizer
  JAACT2022
- Data Source
  KAKENHI-PROJECT-21K04787
[Presentation] Po-210微小線源を用いた一細胞を標的とした三次元照射方法の検討2021
- Author(s)
  角山雄一，堀江正信，五十棲泰人，戸崎充男
- Organizer
  第3回日本放射線安全管理学会・日本保健物理学会合同大会
- Data Source
  KAKENHI-PROJECT-18K11641
[Presentation] SOFT SUBSTRATES PROMOTE SELF-RENEWAL OF HUMAN INDUCED PLURIPOTENT STEM CELLS IN BFGF REDUCED CONDITION2020
- Author(s)
  Masanobu Horie
- Organizer
  International Society for Stem Cell Research Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] Po-210微小線源を用いた局所照射系の評価2019
- Author(s)
  角山雄一，堀江正信，五十棲泰，戸崎充男
- Organizer
  第２回日本放射線安全管理学会・日本保健物理学会合同大会
- Data Source
  KAKENHI-PROJECT-18K11641
[Presentation] Substrate stiffness dependent growth properties of human iPS cells2019
- Author(s)
  Masanobu Horie
- Organizer
  Termi-AP 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] 高効率ヒトiPS細胞由来骨格筋細胞誘導および組織構築プロセスの開発2019
- Author(s)
  Masanobu Horie
- Organizer
  JAACT2019
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] 磁力を用いた三次元筋組織構築とin vitro評価系の開発2019
- Author(s)
  井藤　彰、堀江正信、堀田秋津、櫻井英俊
- Organizer
  骨格筋スマート社会実現コンソーシアム講演会
- Data Source
  KAKENHI-PROJECT-17H03469
[Presentation] ヒトiPS細胞の筋分化誘導条件の検討2019
- Author(s)
  吉開太一、井藤彰、池田一史、吉岡貫太郎、堀江正信、櫻井英俊、堀田秋津、河邉佳典、上平正道
- Organizer
  化学工学会第84年会
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] ヒトiPS細胞由来筋芽細胞の高機能分化誘導法の開発2018
- Author(s)
  吉開太一、井藤彰、池田一史、吉岡貫太郎、堀江正信、河邉佳典、上平正道
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] Substrate stiffness dependent growth properties of human induced pluripotent stem cells2018
- Author(s)
  Masanobu Horie
- Organizer
  Biotechnology Towards Next generation single Cell Analysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] ヒトiPS細胞の筋分化誘導条件の検討2018
- Author(s)
  吉開太一,井藤彰, 池田一史,吉岡貫太郎,堀江正信,櫻井英俊,堀田秋津,河邉佳典,上平正道
- Organizer
  化学工学会
- Data Source
  KAKENHI-PROJECT-17H03469
[Presentation] 複数素材が適用可能なインクジェット式バイオプリンターを利用した細胞パターニングの構築2018
- Author(s)
  Gantumur Enkhtuul、木村美夢、堀江正信、境慎司、中畑雅樹、田谷正仁
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-18K14063
[Presentation] 自己組織化現象を用いた人工骨格筋組織の構築2018
- Author(s)
  丁然、堀江正信、川本卓男
- Organizer
  化学工学会第50回秋季大会
- Data Source
  KAKENHI-PROJECT-18K14063

1. Ito Akira (60345915)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. Tsunoyama Yuichi (90314260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. Kawamoto Takuo (10231276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 戸崎充男 (70207570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 長森英二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 西山雅祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 笹川覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 太田誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 安田恭大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horie Masanobu 堀江 正信

Research Projects

Research Products

Co-Researchers

メカニカルメモリ由来細胞挙動時間遅延性の理解とメカノプロセス創成に向けた基盤研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of functional magnetic nanoparticle for cancer theranostics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メカノセンサー標的型磁性ナノ粒子の創製とヒトiPS細胞精密挙動制御技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preparation of induced pluripotent stem cells through functional enhancement of ES cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of the internal exposure effect in by the single cell - alpha particle Irradiation live imaging system.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research on the creation of innovative human iPS cell culture processes using complex physical stimulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Skeletal muscle tissue engineering using human iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 骨格筋社会を核とした筋スマート社会2019

Author(s)

Publisher

Data Source

[Journal Article] Bone morphogenetic protein signaling inhibitor improves differentiation and function of 3D muscle construct fabricated using C2C122024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Progress of Endogenous and Exogenous Nanoparticles for Cancer Therapy and Diagnostics2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective magnetic hyperthermia induced by mitochondria-targeted nanoparticles modified with triphenylphosphonium-containing phospholipid polymers2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent advances in animal cell technologies for industrial and medical applications2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanowarming of vitrified pancreatic islets as a cryopreservation technology for transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pressure-induced changes on the morphology and gene expression in mammalian cells2021

Author(s)

Journal Title

DOI

Data Source

Horie Masanobu 堀江正信

[Presentation] ヒトiPS細胞の未分化維持培養における物理環境制御によるサイトカイン低減化への試み2023