HORIE MASAFUMI 堀江真史

… Alternative Names

Horie Masafumi 堀江真史

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Researcher Number	60732659
Other IDs	https://orcid.org/0000-0003-1432-8763
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 神戸大学, 医学研究科, 教授 2022 – 2024: 金沢大学, 医学系, 准教授 2022 – 2023: 大阪大学, 大学院医学系研究科, 准教授 2020 – 2021: 大阪大学, 医学系研究科, 准教授 2016: 東京大学, 東京大学保健・健康推進本部, 助教 2015: 東京大学, 保健・健康推進本部, 助教 2014: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnostics / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 56050:Otorhinolaryngology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator CUT&Tag / ATAC-seq / エピジェネティクス / 肺小細胞癌 / ASCL1 / トランスクリプトーム / 病理解剖 / シングルセルRNAseq / microRNA / エピゲノム不均一性 … More / 肺癌 / エピゲノム / 個別化医療 / マスター転写因子 / スーパーエンハンサー / ELF3 / TTF-1 / 薬剤感受性 / AJUBA / NeuroD1 / YAP / クラスタリング解析 / 小細胞肺がん / 予後 / siRNA / マイクロアレイ / バイオマーカー / バイオインフォマティクス / microarray / DNAメチル化 / 非小細胞肺癌 / MYEOV / FANTOM5 / CAGE … More Except Principal Investigator DNAメチル化 / RAS / 甲状腺濾胞癌 / 基底細胞 / 低酸素 / 神経内分泌細胞 / 肥満喘息 / Visium / RAGE / S100A8 / 肥満喘息マウス / innate immunity / allergic inflammation / asthma / necroptosis / 細胞外小胞 / 細胞膜ナノチューブ / 移送開始シグナル / 網羅的遺伝子解析 / 細胞間水平移動 / ミトコンドリア / トランスクリプトーム / 肺線維症 / RNAシーケンス / 初代培養 / 肺胞上皮細胞 / 気管支上皮細胞 / マクロファージ / 線維芽細胞 Less

肺神経内分泌細胞の機能解析および呼吸器疾患病態における役割の解明
- Principal Investigator
  
  齋藤朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Metropolitan Institute for Geriatrics and Gerontology
甲状腺濾胞癌の遠隔転移に関連する分子異常の解明と転移予測マーカーの探索
- Principal Investigator
  
  江口博孝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Osaka
自然免疫系-ネクロトーシスのクロストークと気管支喘息病態の解明
- Principal Investigator
  
  石井崇史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明
- Principal Investigator
  
  松崎博崇
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
剖検検体を活用した肺癌におけるエピゲノム不均一性の解明と新規治療法の探索Principal Investigator
- Principal Investigator
  
  堀江真史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kanazawa University
線維芽細胞・マクロファージの相互作用に着目した肺線維化の病態解明
- Principal Investigator
  
  齋藤朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Understanding of initiation signals of intercellular mitochondria transfer
- Principal Investigator
  
  三木敏生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Nihon University
An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinomaPrincipal Investigator
- Principal Investigator
  
  Horie Masafumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kanazawa University
  Osaka University
トランスクリプトーム・シストローム統合解析による肺小細胞癌転写ネットワークの解明Principal Investigator
- Principal Investigator
  
  堀江真史
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  The University of Tokyo
CAGE identified Myeloma Overexpressed as a novel biomarker for non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Horie Masafumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2016

All Journal Article Presentation

[Journal Article] Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma2023
- Author(s)
  Enokido Takayoshi、Horie Masafumi、Yoshino Seiko、Suzuki Hiroshi I.、Matsuki Rei、Brunnstrom Hans、Micke Patrick、Nagase Takahide、Saito Akira、Miyashita Naoya
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 22 Issue: 1 Pages: 29-40
- DOI
  10.1158/1541-7786.mcr-23-0229
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07210, KAKENHI-PROJECT-22K08277
[Journal Article] An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma2023
- Author(s)
  Horie M, Tanaka H, Suzuki M, Sato Y, Takata S, Takai E, Miyashita N, Saito A, Nakatani Y, Yachida S
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2596-2608
- DOI
  10.1111/cas.15764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06800, KAKENHI-PROJECT-22K08277, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20K16440
[Journal Article] Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells2022
- Author(s)
  Takano Chika、Horie Masafumi、Taiko Isamu、Trinh Quang Duy、Kanemaru Kazunori、Komine-Aizawa Shihoko、Hayakawa Satoshi、Miki Toshio
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 18 Issue: 8 Pages: 3083-3091
- DOI
  10.1007/s12015-022-10420-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19574, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-20K17522, KAKENHI-PROJECT-23K24398
[Journal Article] <scp>ASCL1</scp> regulates super‐enhancer‐associated <scp>miRNAs</scp> to define molecular subtypes of small cell lung cancer2022
- Author(s)
  Miyakawa Kazuko、Miyashita Naoya、Horie Masafumi、Terasaki Yasuhiro、Tanaka Hidenori、Urushiyama Hirokazu、Fukuda Kensuke、Okabe Yugo、Ishii Takashi、Kuwahara Naomi、Suzuki Hiroshi I.、Nagase Takahide、Saito Akira
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 11 Pages: 3932-3946
- DOI
  10.1111/cas.15481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08553, KAKENHI-PROJECT-22K08277
[Journal Article] YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.2016
- Author(s)
  Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 12 Pages: 1755-1766
- DOI
  10.1111/cas.13078
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-26461185, KAKENHI-PROJECT-16K18437
[Presentation] 多面的な単一細胞解析による肺小細胞癌の本態解明の試み～FFPE検体の活用へ～2024
- Author(s)
  堀江真史
- Organizer
  日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07649
[Presentation] ASCL1型肺小細胞癌におけるエピゲノムの全貌解明2023
- Author(s)
  堀江真史, 田中秀憲, 伊藤行信, 宮下直也, 齋藤朗, 前田大地
- Organizer
  日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K07649
[Presentation] シングルセル解析を用いたヒト羊膜上皮細胞の系統学的多様性の解明2023
- Author(s)
  高野智圭, 堀江真史, エルディーブダリア, 早川智, 三木敏生
- Organizer
  第31回日本胎盤学会学術集会/第41回日本絨毛性疾患研究会
- Data Source
  KAKENHI-PROJECT-22K19574
[Presentation] Transcriptome Analysis of Small Cell Lung Cancer2016
- Author(s)
  Masafumi Horie
- Organizer
  2016 American Thoracic Society International Conference
- Place of Presentation
  San Francisco, California
- Year and Date
  2016-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18437
[Presentation] 肺小細胞癌のトランスクリプトーム解析2016
- Author(s)
  堀江真史
- Organizer
  第56回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-04-10
- Data Source
  KAKENHI-PROJECT-16K18437
[Presentation] 肺小細胞癌のトランスクリプトーム解析2016
- Author(s)
  堀江真史
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K18437

1. 齋藤朗 (90591412)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. 鹿毛秀宣 (80513390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 石井崇史 (30803118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 福田健介 (50910759)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 漆山博和 (20725303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 三木敏生 (80845305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 太向勇 (20836556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 鈴川真穂 (20453699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松崎博崇 (00782187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田中秀憲 (00804379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 三上優 (50732806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 江口博孝 (90844936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鈴木雅美 (80434182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TERASAKI Mika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 長瀬隆英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 芳野聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 寺崎泰弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HORIE MASAFUMI 堀江 真史

Horie Masafumi 堀江 真史

Research Projects

Research Products

Co-Researchers

肺神経内分泌細胞の機能解析および呼吸器疾患病態における役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

甲状腺濾胞癌の遠隔転移に関連する分子異常の解明と転移予測マーカーの探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自然免疫系-ネクロトーシスのクロストークと気管支喘息病態の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

S100A8―RAGEシグナルに着目した肥満関連喘息の病態の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

剖検検体を活用した肺癌におけるエピゲノム不均一性の解明と新規治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

線維芽細胞・マクロファージの相互作用に着目した肺線維化の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of initiation signals of intercellular mitochondria transfer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

トランスクリプトーム・シストローム統合解析による肺小細胞癌転写ネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CAGE identified Myeloma Overexpressed as a novel biomarker for non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells2022

Author(s)

Journal Title

DOI

Data Source

HORIE MASAFUMI 堀江真史

Horie Masafumi 堀江真史