Tanoue Takeshi 田之上大

… Alternative Names

TANOUE Takeshi 田之上大

Less

Researcher Number	60732972
Affiliation (Current)	2026: 慶應義塾大学, 医学部(信濃町), 准教授 2026: 国立研究開発法人理化学研究所, 生命医科学研究センター, 客員研究員
Affiliation (based on the past Project Information) *help	2024 – 2025: 慶應義塾大学, 医学部(信濃町), 准教授 2021 – 2022: 慶應義塾大学, 医学部(信濃町), 講師 2017 – 2019: 慶應義塾大学, 医学部(信濃町), 講師 2015 – 2016: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 基礎科学特別研究員 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 49050:Bacteriology-related / Basic Section 49070:Immunology-related
Keywords	Principal Investigator 腸内細菌 / 宿主代謝系 / 代謝 / 脂肪酸 / 細胞障害性T細胞 / CD8 T細胞 / IFNgamma / CD8 / CD8T / Microbiota / IL-22 / 腸内常在菌 / IL22

Study of gut microbiota contributing to host metabolic homeostasisPrincipal Investigator
- Principal Investigator
  
  田之上大
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Keio University
Analysis of intestinal bacteria contributing to fatty acid metabolism and their effects on host physiological functionsPrincipal Investigator
- Principal Investigator
  
  Tanoue Takeshi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Keio University
Study for mechanisms underlying microbiota-mediated modulation of cytotoxic T cellsPrincipal Investigator
- Principal Investigator
  
  TANOUE Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Keio University
Understanding of the mechanism for inducing IFNgamma-producing CD8T cells in the gutPrincipal Investigator
- Principal Investigator
  
  Tanoue Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Keio University
  Institute of Physical and Chemical Research
Understanding for the induction mechanisms of intestinal IL22-producing cellsPrincipal Investigator
- Principal Investigator
  
  Tanoue Takeshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Institute of Physical and Chemical Research

All 2019 2018 2017 2015 2014

All Journal Article Presentation Patent

[Journal Article] A defined commensal consortium elicits CD8 T cells and anti-cancer immunity2019
- Author(s)
  T.Tanoue, S.Morita, D.R.Plichta, A.N.Skelly, W.Suda, Y.Sugiura, S.Narushima, H.Vlamakis, I.Motoo, K.Sugita, A.Shiota, K.Takeshita, K.Yasuma, D.Riethmacher, T.Kaisho, J.M.Norman, D.Mucida, M.Suematsu, T.Yaguchi, V.Bucci, T.Inoue, Y.Kawakami, B.Olle, B.Roberts, M.Hattori, R.J.Xavier, K.Atarashi, K.Honda
- Journal Title
  
  Nature
  
  Volume: 565 Issue: 7741 Pages: 600-605
- DOI
  10.1038/s41586-019-0878-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05799, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-17H04088, KAKENHI-PROJECT-17J01289, KAKENHI-PROJECT-17K19568, KAKENHI-PUBLICLY-19H04813, KAKENHI-PROJECT-16K08091, KAKENHI-PROJECT-16K19165
[Journal Article] 腸内細菌叢によるがん免疫応答調節2019
- Author(s)
  田之上大、本田賢也
- Journal Title
  
  実験医学増刊
  
  Volume: 37 Pages: 97-101
- Data Source
  KAKENHI-PROJECT-19K16698
[Journal Article] T細胞を誘導する腸内常在菌とがん免疫への関与2019
- Author(s)
  田之上大、新　幸二、本田賢也
- Journal Title
  
  実験医学増刊
  
  Volume: 37 Pages: 67-72
- Data Source
  KAKENHI-PROJECT-16K19165
[Journal Article] T細胞を誘導する腸内常在菌とがん免疫への関与2019
- Author(s)
  田之上大、新　幸二、本田賢也
- Journal Title
  
  実験医学増刊
  
  Volume: 37 Pages: 67-72
- Data Source
  KAKENHI-PROJECT-19K16698
[Journal Article] Computer-guided design of optimal microbial consortia for immune system modulation2018
- Author(s)
  Stein Richard R、Tanoue Takeshi、Szabady Rose L、Bhattarai Shakti K、Olle Bernat、Norman Jason M、Suda Wataru、Oshima Kenshiro、Hattori Masahira、Gerber Georg K、Sander Chris、Honda Kenya、Bucci Vanni
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.30916
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19165
[Journal Article] 腸内フローラとTH17細胞2017
- Author(s)
  田之上大、新　幸二、本田賢也
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35 Pages: 1290-1292
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19165
[Journal Article] Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation" Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammationx2017
- Author(s)
  Atarashi K, Suda W, Luo C, Kawaguchi T, Motoo I, Narushima S, Kiguchi Y, Yasuma K, Watanabe E, Tanoue T, Thaiss CA, Sato M, Toyooka K, Said HS, Yamagami H, Rice SA, Gevers D, Johnson RC, Segre JA, Chen K, Kolls JK, Elinav E, Morita H, Xavier RJ, Hattori M, Honda K.
- Journal Title
  
  Science
  
  Volume: 358 Issue: 6361 Pages: 359-365
- DOI
  10.1126/science.aan4526
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07477, KAKENHI-PROJECT-16K15293, KAKENHI-PROJECT-15H05657, KAKENHI-PROJECT-16K19165
[Journal Article] Helicobacterspecies are potent drivers of colonic T cell responses in homeostasis and inflammation2017
- Author(s)
  Chai Jiani N.、Peng Yangqing、Rengarajan Sunaina、Solomon Benjamin D.、Ai Teresa L.、Shen Zeli、Perry Justin S. A.、Knoop Kathryn A.、Tanoue Takeshi、Narushima Seiko、Honda Kenya、Elson Charles O.、Newberry Rodney D.、Stappenbeck Thaddeus S.、Kau Andrew L.、Peterson Daniel A.、Fox James G.、Hsieh Chyi-Song
- Journal Title
  
  Science Immunology
  
  Volume: 2 Issue: 13
- DOI
  10.1126/sciimmunol.aal5068
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19165
[Journal Article] Th17 Cell induction by adhesion of microbes to intestinal epithelial cells2015
- Author(s)
  Atarashi, K., Tanoue, T., Ando. M., Kamada, N., Nagano, Y., Narushima, S., Suda, W., Imaoka, A., Setoyama, H., Nagamori, T., Ishikawa, E., Shima, T., Hara, T., Kado, S., Jinnohara, T., Ohno, H., Kondo, T. et al.
- Journal Title
  
  Cell
  
  Volume: 163 Issue: 2 Pages: 367-380
- DOI
  10.1016/j.cell.2015.08.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15076, KAKENHI-PROJECT-15H05657, KAKENHI-PROJECT-26893326, KAKENHI-PROJECT-24687007
[Patent] 腸管IFNg産生CD8T細胞を誘導するヒト常在細菌種の同定2017
- Inventor(s)
  本田賢也、田之上大、服部正平
- Industrial Property Rights Holder
  本田賢也、田之上大、服部正平
- Industrial Property Rights Type
  特許
- Filing Date
  2017-02-10
- Overseas
- Data Source
  KAKENHI-PROJECT-16K19165
[Presentation] 宿主免疫系に作用する腸内細菌種の同定とそのがん免疫応答に及ぼす影響2019
- Author(s)
  田之上　大
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16698
[Presentation] A human-derived commensal bacteria that can induce IFNγ-producing CD8 T cells and cancer immunity.2019
- Author(s)
  Takeshi TANOUE, Kenya HONDA
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16698
[Presentation] Commensal bacteria that can induce CD8 T cells and cancer immunity.2018
- Author(s)
  Takeshi TANOUE, Koji ATARASHI, Kenya HONDA
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19165
[Presentation] Induction of IFNγ-producing CD8 T cells by human derivedcommensal bacteria2018
- Author(s)
  1.Takeshi TANOUE, Ashwin SKELLY, Satoru MORITA, Seiko NARUSHIMA, Koji ATARASHI, Kenya HONDA
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19165
[Presentation] Microbiota-dependent induction of IL-22-producing ILC3 in the gut2014
- Author(s)
  Takeshi TANOUE, Koji ATARASHI, Yuji NAGANO, Seiko NARUSHIMA, Yoshinori UMESAKI, Kenya HONDA
- Organizer
  The 43rd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26893326

1. SUDA Wataru

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 改正恒康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 豊岡公徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 近藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanoue Takeshi 田之上 大

TANOUE Takeshi 田之上 大

Research Projects

Research Products

Co-Researchers

Study of gut microbiota contributing to host metabolic homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of intestinal bacteria contributing to fatty acid metabolism and their effects on host physiological functionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for mechanisms underlying microbiota-mediated modulation of cytotoxic T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding of the mechanism for inducing IFNgamma-producing CD8T cells in the gutPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding for the induction mechanisms of intestinal IL22-producing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A defined commensal consortium elicits CD8 T cells and anti-cancer immunity2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 腸内細菌叢によるがん免疫応答調節2019

Author(s)

Journal Title

Data Source

[Journal Article] T細胞を誘導する腸内常在菌とがん免疫への関与2019

Author(s)

Journal Title

Data Source

[Journal Article] T細胞を誘導する腸内常在菌とがん免疫への関与2019

Author(s)

Journal Title

Data Source

[Journal Article] Computer-guided design of optimal microbial consortia for immune system modulation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 腸内フローラとTH17細胞2017

Author(s)

Journal Title

Data Source

[Journal Article] Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation" Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammationx2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Helicobacterspecies are potent drivers of colonic T cell responses in homeostasis and inflammation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Th17 Cell induction by adhesion of microbes to intestinal epithelial cells2015

Author(s)

Journal Title

DOI

Data Source

[Patent] 腸管IFNg産生CD8T細胞を誘導するヒト常在細菌種の同定2017

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Tanoue Takeshi 田之上大

TANOUE Takeshi 田之上大